5IJEA

Crystal structure of equine serum albumin in the presence of 30 mm zinc at ph 7.4
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
581
structure length
581
Chain Sequence
HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Serum albumin
publication title Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
pubmed doi rcsb
molecule tags Transport protein
total genus 224
structure length 581
sequence length 581
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA05
2BX8A 1TF0A 2VDBA 4OT2A 4N0FD 4LB2A 2BXDA 2VUEA 2BXOA 1E7EA 4G04A 4E99A 5IIHA 4N0UD 2BXQA 3TDLA 4L9QA 5FUOA 2BXGA 1KXPD 2BXCA 2BXNA 5HOZA 4HGMB 2XW0A 1GNIA 3JRYA 2YDFA 5IJ5A 5ID7A 1J7EA 2XSIA 4LUFA 1E7HA 4ZBRA 4F5VA 1J78A 1H9ZA 2BXMA 4F5SA 1E7FA 3A73A 5IIXA 1HA2A 3B9LA 2BXFA 3B9MA 3V08A 1UORA 2I2ZA 2BXLA 2BXKA 2BXHA 1BJ5A 1N5UA 1GNJA 4K71A 5IFOA 4L8UA 5GHKA 5ID9A 2XVVA 1E7IA 4Z69A 2BXAA 4HGKA 1E7CA 1HK3A 3CX9A 2XVWA 3JQZA 1HK2A 3V09A 4BKEA 1AO6A 2XVUA 4LUHA 2VUFA 4LA0A 4OR0A 1E7BA 5DBYA 1O9XA 5IJEA 1MA9A 4PO0A 1HK1A 5IJFA 1HK4A 1HK5A 2BXIA 2I30A 1BM0A 1E78A 2BXBA 2BXEA 3UIVA 1LOTA 5IIUA 4IW2A 3SQJA 4G03A 4J2VA 1KW2A 4IW1A 4F5UA 4F5TA 1BKEA 2BXPA 4K2CA 4L9KA 4EMXA 4JK4A 4LB9A 4S1YA 3V03A 5DQFA 2XVQA 2XW1A 4ZBQA 1E7AA 3LU8A 3LU7A 3LU6A 1E7GA
chains in the Genus database with same CATH superfamily
2LQIA 2BX8A 1TF0A 2DBWA 2VDBA 1H5WA 4OT2A 2EFCA 4TQ1A 4N0FD 4LB2A 3NVMA 2QM6A 4NAWB 4Z9OA 2BXDA 2VUEA 2BXOA 1E7EA 5GIOA 4G04A 4E99A 5IIHA 4N0UD 2BXQA 2OT3A 1MM8A 3TDLA 4L9QA 3MHHB 4ZCGA 5FUOA 5GIPA 4G01A 1SB0A 4N3ZA 2BXGA 4ZC6A 1KXPD 2BXCA 3KJLA 2BXNA 5HOZA 4HGMB 2EFEA 1GNIA 2XW0A 2YDFA 3JRYA 4DM0A 5IJ5A 5ID7A 1J7EA 4GG2A 4OTTA 4C31B 2LQHA 2LXTA 2XSIA 2NNWA 4LUFA 1FOUA 2LXSA 3GA9L 1E7HA 4ZBRA 4F5VA 3NVIA 1J78A 1H9ZA 2BXMA 4GDXA 2E0XA 4F5SA 2K0NA 2LOQA 2AGHB 5GINA 3SIVB 1E7FA 3A73A 3FWCC 5IIXA 1HA2A 3B9LA 3GQXA 4OTUA 2BXFA 3B9MA 1TXUA 3V08A 2E0YA 1UORA 1MIYA 2I2ZA 4FIPB 2BXLA 2BXKA 2BXHA 2GUTA 1BJ5A 1N5UA 1GNJA 1VZSA 2KBZA 4K71A 4L8UA 5IFOA 5GHKA 5ID9A 2XVVA 2DBXA 1E7IA 4Z69A 2BXAA 2V36A 2DYOA 4HGKA 1E7CA 1VFIA 5D7GA 1HK3A 3CX9A 2XVWA 3JQZA 1HK2A 3V09A 4BKEA 1JNBA 1AO6A 2QHBA 4W4UB 3VQIA 3WHRA 2XVUA 4LUHA 3ICXA 3W1SA 2VUFA 4LA0A 4MBEC 1E7BA 4OR0A 1O9XA 5DBYA 3NMUA 2AJEA 5IJEA 4ZUXV 4GDLB 1MUHA 1MA9A 4I9OA 1MIVA 4PO0A 4TQ0A 1HK1A 4D7XA 5IJFA 3H37A 1HK4A 1HK5A 2EFHA 3PLAA 2BXIA 2I30A 1KDXA 1BM0A 1E78A 2BXEA 1NT2B 2BXBA 2NQOA 3UIVA 2OZBB 3H3AA 1LOTA 3M99C 3FNMA 5IIUA 4IW2A 1LNSA 2JUHA 3SQJA 2Z8KA 4G03A 4M70B 4FJCB 1IJGA 3A75A 3KIKA 3MHSB 2QMCA 1KW2A 4J2VA 4FK5B 4IW1A 3WHSA 3SIUB 4F5UA 3BPJA 4GDKB 2KWFA 4F5TA 1BKEA 2BXPA 4K2CA 4L9KA 4EMXA 5B5TA 3ECPA 4WA6B 3G9KD 3FWBC 4JK4A 2Z8IA 4LB9A 2DYMA 4S1YA 4ZBKA 3GQUA 3V03A 5DQFA 2DBUA 2XVQA 2XW1A 2DG5A 4ZBQA 4BY9C 1E7AA 3LU8A 2XMOA 2Z8JA 3WHQA 2CKXA 5BPKA 1MIWA 3NVKA 2EFDA 3LU7A 2ROHA 3LU6A 4DHXB 1E7GA 1MUSA
chains in the Genus database with same CATH topology
2BX8A 1TF0A 2DBWA 2VDBA 1H5WA 4OT2A 2EFCA 4TQ1A 4N0FD 4LB2A 3NVMA 2QM6A 4NAWB 4Z9OA 2BXDA 2VUEA 2BXOA 1E7EA 5GIOA 4G04A 4E99A 5IIHA 4N0UD 2BXQA 2OT3A 3TDLA 4L9QA 3MHHB 4ZCGA 5FUOA 5GIPA 4G01A 4N3ZA 2BXGA 4ZC6A 1KXPD 2BXCA 3KJLA 2BXNA 5HOZA 4HGMB 2EFEA 1GNIA 2XW0A 2YDFA 3JRYA 5IJ5A 5ID7A 1J7EA 4GG2A 4OTTA 4C31B 2XSIA 2NNWA 4LUFA 1FOUA 3GA9L 1E7HA 4ZBRA 4F5VA 3NVIA 1J78A 1H9ZA 2BXMA 4GDXA 2E0XA 4F5SA 2LOQA 5GINA 3SIVB 1E7FA 3A73A 3FWCC 5IIXA 1HA2A 3B9LA 3GQXA 4OTUA 2BXFA 3B9MA 1TXUA 3V08A 2E0YA 1UORA 1MIYA 2I2ZA 4FIPB 2BXLA 2BXKA 2BXHA 1BJ5A 1N5UA 1GNJA 1VZSA 2KBZA 4K71A 4L8UA 5IFOA 5GHKA 5ID9A 2XVVA 2DBXA 1E7IA 4Z69A 2BXAA 2V36A 2DYOA 4HGKA 1E7CA 1VFIA 5D7GA 1HK3A 3CX9A 2XVWA 3JQZA 1HK2A 3V09A 4BKEA 1JNBA 1AO6A 2QHBA 4W4UB 3VQIA 3WHRA 2XVUA 4LUHA 3ICXA 3W1SA 2VUFA 4LA0A 4MBEC 1E7BA 4OR0A 1O9XA 5DBYA 3NMUA 2AJEA 5IJEA 4ZUXV 4GDLB 1MA9A 4PO0A 1MIVA 4TQ0A 1HK1A 5IJFA 3H37A 1HK4A 1HK5A 2EFHA 3PLAA 2I30A 2BXIA 1BM0A 1E78A 1NT2B 2BXBA 2BXEA 2NQOA 3UIVA 2OZBB 3H3AA 1LOTA 3M99C 3FNMA 5IIUA 4IW2A 1LNSA 2JUHA 3SQJA 2Z8KA 4G03A 4M70B 4FJCB 1IJGA 3A75A 3KIKA 3MHSB 2QMCA 1KW2A 4J2VA 4FK5B 4IW1A 3WHSA 3SIUB 4F5UA 4GDKB 4F5TA 1BKEA 2BXPA 4K2CA 4L9KA 4EMXA 5B5TA 4WA6B 3G9KD 3FWBC 4JK4A 2Z8IA 4LB9A 2DYMA 4S1YA 4ZBKA 3GQUA 3V03A 5DQFA 2DBUA 2XVQA 2XW1A 2DG5A 4ZBQA 4BY9C 1E7AA 3LU8A 2XMOA 2Z8JA 3WHQA 2CKXA 5BPKA 1MIWA 3NVKA 2EFDA 3LU7A 2ROHA 3LU6A 4DHXB 1E7GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BX8 A;  1TF0 A;  2VDB A;  4OT2 A;  4N0F D;  4LB2 A;  2BXD A;  2VUE A;  2BXO A;  1E7E A;  4G04 A;  4E99 A;  5IIH A;  4N0U D;  2BXQ A;  3TDL A;  4L9Q A;  5FUO A;  2BXG A;  1KXP D;  2BXC A;  2BXN A;  5HOZ A;  4HGM B;  2XW0 A;  1GNI A;  3JRY A;  2YDF A;  5IJ5 A;  5ID7 A;  1J7E A;  2XSI A;  4LUF A;  1E7H A;  4ZBR A;  4F5V A;  1J78 A;  1H9Z A;  2BXM A;  4F5S A;  1E7F A;  3A73 A;  5IIX A;  1HA2 A;  3B9L A;  2BXF A;  3B9M A;  3V08 A;  1UOR A;  2I2Z A;  2BXL A;  2BXK A;  2BXH A;  1BJ5 A;  1N5U A;  1GNJ A;  4K71 A;  5IFO A;  4L8U A;  5GHK A;  5ID9 A;  2XVV A;  1E7I A;  4Z69 A;  2BXA A;  4HGK A;  1E7C A;  1HK3 A;  3CX9 A;  2XVW A;  3JQZ A;  1HK2 A;  3V09 A;  4BKE A;  1AO6 A;  2XVU A;  4LUH A;  2VUF A;  4LA0 A;  4OR0 A;  1E7B A;  5DBY A;  1O9X A;  5IJE A;  1MA9 A;  4PO0 A;  1HK1 A;  5IJF A;  1HK4 A;  1HK5 A;  2BXI A;  2I30 A;  1BM0 A;  1E78 A;  2BXB A;  2BXE A;  3UIV A;  1LOT A;  5IIU A;  4IW2 A;  3SQJ A;  4G03 A;  4J2V A;  1KW2 A;  4IW1 A;  4F5U A;  4F5T A;  1BKE A;  2BXP A;  4K2C A;  4L9K A;  4EMX A;  4JK4 A;  4LB9 A;  4S1Y A;  3V03 A;  5DQF A;  2XVQ A;  2XW1 A;  4ZBQ A;  1E7A A;  3LU8 A;  3LU7 A;  3LU6 A;  1E7G A; 
#chains in the Genus database with same CATH topology
 2LQI A;  2BX8 A;  1TF0 A;  2DBW A;  2VDB A;  1H5W A;  4OT2 A;  2EFC A;  4TQ1 A;  4N0F D;  4LB2 A;  3NVM A;  2QM6 A;  4NAW B;  4Z9O A;  2BXD A;  2VUE A;  2BXO A;  1E7E A;  5GIO A;  4G04 A;  4E99 A;  5IIH A;  4N0U D;  2BXQ A;  2OT3 A;  1MM8 A;  3TDL A;  4L9Q A;  3MHH B;  4ZCG A;  5FUO A;  5GIP A;  4G01 A;  1SB0 A;  4N3Z A;  2BXG A;  4ZC6 A;  1KXP D;  2BXC A;  3KJL A;  2BXN A;  5HOZ A;  4HGM B;  2EFE A;  1GNI A;  2XW0 A;  2YDF A;  3JRY A;  4DM0 A;  5IJ5 A;  5ID7 A;  1J7E A;  4GG2 A;  4OTT A;  4C31 B;  2LQH A;  2LXT A;  2XSI A;  2NNW A;  4LUF A;  1FOU A;  2LXS A;  3GA9 L;  1E7H A;  4ZBR A;  4F5V A;  3NVI A;  1J78 A;  1H9Z A;  2BXM A;  4GDX A;  2E0X A;  4F5S A;  2K0N A;  2LOQ A;  2AGH B;  5GIN A;  3SIV B;  1E7F A;  3A73 A;  3FWC C;  5IIX A;  1HA2 A;  3B9L A;  3GQX A;  4OTU A;  2BXF A;  3B9M A;  1TXU A;  3V08 A;  2E0Y A;  1UOR A;  1MIY A;  2I2Z A;  4FIP B;  2BXL A;  2BXK A;  2BXH A;  2GUT A;  1BJ5 A;  1N5U A;  1GNJ A;  1VZS A;  2KBZ A;  4K71 A;  4L8U A;  5IFO A;  5GHK A;  5ID9 A;  2XVV A;  2DBX A;  1E7I A;  4Z69 A;  2BXA A;  2V36 A;  2DYO A;  4HGK A;  1E7C A;  1VFI A;  5D7G A;  1HK3 A;  3CX9 A;  2XVW A;  3JQZ A;  1HK2 A;  3V09 A;  4BKE A;  1JNB A;  1AO6 A;  2QHB A;  4W4U B;  3VQI A;  3WHR A;  2XVU A;  4LUH A;  3ICX A;  3W1S A;  2VUF A;  4LA0 A;  4MBE C;  1E7B A;  4OR0 A;  1O9X A;  5DBY A;  3NMU A;  2AJE A;  5IJE A;  4ZUX V;  4GDL B;  1MUH A;  1MA9 A;  4I9O A;  1MIV A;  4PO0 A;  4TQ0 A;  1HK1 A;  4D7X A;  5IJF A;  3H37 A;  1HK4 A;  1HK5 A;  2EFH A;  3PLA A;  2BXI A;  2I30 A;  1KDX A;  1BM0 A;  1E78 A;  2BXE A;  1NT2 B;  2BXB A;  2NQO A;  3UIV A;  2OZB B;  3H3A A;  1LOT A;  3M99 C;  3FNM A;  5IIU A;  4IW2 A;  1LNS A;  2JUH A;  3SQJ A;  2Z8K A;  4G03 A;  4M70 B;  4FJC B;  1IJG A;  3A75 A;  3KIK A;  3MHS B;  2QMC A;  1KW2 A;  4J2V A;  4FK5 B;  4IW1 A;  3WHS A;  3SIU B;  4F5U A;  3BPJ A;  4GDK B;  2KWF A;  4F5T A;  1BKE A;  2BXP A;  4K2C A;  4L9K A;  4EMX A;  5B5T A;  3ECP A;  4WA6 B;  3G9K D;  3FWB C;  4JK4 A;  2Z8I A;  4LB9 A;  2DYM A;  4S1Y A;  4ZBK A;  3GQU A;  3V03 A;  5DQF A;  2DBU A;  2XVQ A;  2XW1 A;  2DG5 A;  4ZBQ A;  4BY9 C;  1E7A A;  3LU8 A;  2XMO A;  2Z8J A;  3WHQ A;  2CKX A;  5BPK A;  1MIW A;  3NVK A;  2EFD A;  3LU7 A;  2ROH A;  3LU6 A;  4DHX B;  1E7G A;  1MUS A; 
#chains in the Genus database with same CATH homology
 2BX8 A;  1TF0 A;  2DBW A;  2VDB A;  1H5W A;  4OT2 A;  2EFC A;  4TQ1 A;  4N0F D;  4LB2 A;  3NVM A;  2QM6 A;  4NAW B;  4Z9O A;  2BXD A;  2VUE A;  2BXO A;  1E7E A;  5GIO A;  4G04 A;  4E99 A;  5IIH A;  4N0U D;  2BXQ A;  2OT3 A;  3TDL A;  4L9Q A;  3MHH B;  4ZCG A;  5FUO A;  5GIP A;  4G01 A;  4N3Z A;  2BXG A;  4ZC6 A;  1KXP D;  2BXC A;  3KJL A;  2BXN A;  5HOZ A;  4HGM B;  2EFE A;  1GNI A;  2XW0 A;  2YDF A;  3JRY A;  5IJ5 A;  5ID7 A;  1J7E A;  4GG2 A;  4OTT A;  4C31 B;  2XSI A;  2NNW A;  4LUF A;  1FOU A;  3GA9 L;  1E7H A;  4ZBR A;  4F5V A;  3NVI A;  1J78 A;  1H9Z A;  2BXM A;  4GDX A;  2E0X A;  4F5S A;  2LOQ A;  5GIN A;  3SIV B;  1E7F A;  3A73 A;  3FWC C;  5IIX A;  1HA2 A;  3B9L A;  3GQX A;  4OTU A;  2BXF A;  3B9M A;  1TXU A;  3V08 A;  2E0Y A;  1UOR A;  1MIY A;  2I2Z A;  4FIP B;  2BXL A;  2BXK A;  2BXH A;  1BJ5 A;  1N5U A;  1GNJ A;  1VZS A;  2KBZ A;  4K71 A;  4L8U A;  5IFO A;  5GHK A;  5ID9 A;  2XVV A;  2DBX A;  1E7I A;  4Z69 A;  2BXA A;  2V36 A;  2DYO A;  4HGK A;  1E7C A;  1VFI A;  5D7G A;  1HK3 A;  3CX9 A;  2XVW A;  3JQZ A;  1HK2 A;  3V09 A;  4BKE A;  1JNB A;  1AO6 A;  2QHB A;  4W4U B;  3VQI A;  3WHR A;  2XVU A;  4LUH A;  3ICX A;  3W1S A;  2VUF A;  4LA0 A;  4MBE C;  1E7B A;  4OR0 A;  1O9X A;  5DBY A;  3NMU A;  2AJE A;  5IJE A;  4ZUX V;  4GDL B;  1MA9 A;  4PO0 A;  1MIV A;  4TQ0 A;  1HK1 A;  5IJF A;  3H37 A;  1HK4 A;  1HK5 A;  2EFH A;  3PLA A;  2I30 A;  2BXI A;  1BM0 A;  1E78 A;  1NT2 B;  2BXB A;  2BXE A;  2NQO A;  3UIV A;  2OZB B;  3H3A A;  1LOT A;  3M99 C;  3FNM A;  5IIU A;  4IW2 A;  1LNS A;  2JUH A;  3SQJ A;  2Z8K A;  4G03 A;  4M70 B;  4FJC B;  1IJG A;  3A75 A;  3KIK A;  3MHS B;  2QMC A;  1KW2 A;  4J2V A;  4FK5 B;  4IW1 A;  3WHS A;  3SIU B;  4F5U A;  4GDK B;  4F5T A;  1BKE A;  2BXP A;  4K2C A;  4L9K A;  4EMX A;  5B5T A;  4WA6 B;  3G9K D;  3FWB C;  4JK4 A;  2Z8I A;  4LB9 A;  2DYM A;  4S1Y A;  4ZBK A;  3GQU A;  3V03 A;  5DQF A;  2DBU A;  2XVQ A;  2XW1 A;  2DG5 A;  4ZBQ A;  4BY9 C;  1E7A A;  3LU8 A;  2XMO A;  2Z8J A;  3WHQ A;  2CKX A;  5BPK A;  1MIW A;  3NVK A;  2EFD A;  3LU7 A;  2ROH A;  3LU6 A;  4DHX B;  1E7G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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