5INHA

Crystal structure of autotaxin/enpp2 with a covalent fragment
Total Genus 257
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
257
sequence length
807
structure length
780
Chain Sequence
NTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMGCTCDGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes.
pubmed doi rcsb
source organism Mus musculus
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 257
structure length 780
sequence length 807
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2016-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 5inhA04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5inhA03
1KHKA 3S5BA 1Y7AA 2W5QA 3NKPA 2QZUA 1FSUA 3E2DA 4QAXA 1KH4A 1KH7A 4A1NA 5LRNA 1SHNA 5IJSA 1ALIA 4GTXA 2IUCB 3ED4A 1QL0A 5AJ9A 4MHXA 1Y6VA 2W5WA 1ED8A 2O3BA 5EGHA 4YR1A 4UORA 1P49A 2W5SA 2ZKTA 5K4PA 1EQJA 3MK2A 4GTWA 4CYSA 1ALHA 3TWZA 1G8TA 1ELZA 4LRDA 2D1GA 4KJGA 4UPHA 3DYCA 3NVLA 3WBHA 2GSNA 4MY4A 2G9YA 3LXQA 3OWVA 2VQRA 2W5TA 1ZEFA 3IGYB 5GRRA 4CXUA 1ZM8A 2W8DA 2RH6A 4KJDA 3T01A 4CXKA 1QAEA 1N2LA 1B8JA 1K7HA 1URAA 3T02A 2GSUA 3B5QA 3CMRA 1KHJA 4QN0A 1AJAA 4LR2A 5LRMA 1HDHA 1KH9A 2GSOA 5DLTA 4MIVA 1E3CP 4QGOA 1SHQA 3UN2A 3WAWA 3M8ZA 1EI6A 4NWJA 4LR7A 3UN5A 2X98A 2W5XA 4UOPA 1ELXA 4KAVA 4KM4A 4GTZA 5L0KA 3UNYA 3WAVA 3MK1A 5LIAA 4LREA 4ZG6A 1E33P 3BDFA 3A52A 5TJ3A 3NKRA 4LRFA 3IDDA 1E2SP 1AJDA 5LQQA 1EW2A 1O98A 3KD8A 4LR8A 4NWXA 1ANIA 5GOVA 2ANHA 3BDGB 4ZG9A 1KH5A 4KAYA 2XH3A 2XGRA 2GLQA 5INHA 3UN3A 1HJKA 3M7VA 4CYRA 1KHNA 3T00A 3M8WA 4LR9A 5EGEA 1EW8A 3TG0A 1ZEDA 3NKMA 2XRGA 5IJQA 1O99A 4CXSA 1SMNA 4LRCA 5HRTA 1HQAA 4UOOA 5KXAA 3ISMA 5L0EA 1EJJA 3SZZA 4ZGAA 1KHLA 2GA3A 2XR9A 3Q3QA 4UPIA 3SZYA 1AJBA 3NKNA 5DLWA 4UPKA 4B56A 1URBA 3BDGA 4LQYA 4LRAA 1N2KA 4LRBA 3UO0A 5L0BA 3WAXA 3IGZB 1ALJA 3M8YA 4UPLA 3NKQA 4E3YA 2W5VA 2W8SA 4ZG7A 1ALKA 1E1ZP 3NKOA 5DLVA 2W5RA 1AUKA 3MK0A 4N7TA 1ELYA 3BDHA 1AJCA 4QH0A 5GKCA 3WAYA 4TN0A 3TX0A 2IUCA 5C66A 3OT9A 1ZEBA 1ED9A 5GKPA 3DPCA 4FDIA 1EW9A 4GTYA 2IFYA 1ANJA 4FDJA
chains in the Genus database with same CATH superfamily
1KHKA 3S5BA 1Y7AA 2W5QA 3NKPA 2QZUA 1FSUA 3E2DA 4QAXA 1KH4A 1KH7A 4A1NA 5LRNA 1SHNA 5IJSA 1ALIA 4GTXA 2IUCB 3ED4A 1QL0A 5AJ9A 4MHXA 1Y6VA 2W5WA 1ED8A 2O3BA 5EGHA 4YR1A 4UORA 1P49A 2W5SA 2ZKTA 5K4PA 1EQJA 3MK2A 4GTWA 4CYSA 1ALHA 3TWZA 1G8TA 1ELZA 4LRDA 2D1GA 4KJGA 4UPHA 3DYCA 3NVLA 3WBHA 2GSNA 4MY4A 2G9YA 3LXQA 3OWVA 2VQRA 2W5TA 1ZEFA 3IGYB 5GRRA 4CXUA 1ZM8A 2W8DA 2RH6A 4KJDA 3T01A 4CXKA 1QAEA 1N2LA 1B8JA 1K7HA 1URAA 3T02A 2GSUA 3B5QA 3CMRA 1KHJA 4QN0A 1AJAA 4LR2A 5LRMA 1HDHA 1KH9A 2GSOA 5DLTA 4MIVA 1E3CP 4QGOA 1SHQA 3UN2A 3WAWA 3M8ZA 1EI6A 4NWJA 4LR7A 3UN5A 2X98A 2W5XA 4UOPA 1ELXA 4KAVA 4KM4A 4GTZA 5L0KA 3UNYA 3WAVA 3MK1A 5LIAA 4LREA 4ZG6A 1E33P 3BDFA 3A52A 5TJ3A 3NKRA 4LRFA 3IDDA 1E2SP 1AJDA 5LQQA 1EW2A 1O98A 3KD8A 4LR8A 4NWXA 1ANIA 5GOVA 2ANHA 3BDGB 4ZG9A 1KH5A 4KAYA 2XH3A 2XGRA 2GLQA 5INHA 3UN3A 1HJKA 3M7VA 4CYRA 1KHNA 3T00A 3M8WA 4LR9A 5EGEA 1EW8A 3TG0A 1ZEDA 3NKMA 2XRGA 5IJQA 1O99A 4CXSA 1SMNA 4LRCA 5HRTA 1HQAA 4UOOA 5KXAA 3ISMA 5L0EA 1EJJA 3SZZA 4ZGAA 1KHLA 2GA3A 2XR9A 3Q3QA 4UPIA 3SZYA 1AJBA 3NKNA 5DLWA 4UPKA 4B56A 1URBA 3BDGA 4LQYA 4LRAA 1N2KA 4LRBA 3UO0A 5L0BA 3WAXA 3IGZB 1ALJA 3M8YA 4UPLA 3NKQA 4E3YA 2W5VA 2W8SA 4ZG7A 1ALKA 1E1ZP 3NKOA 5DLVA 2W5RA 1AUKA 3MK0A 4N7TA 1ELYA 3BDHA 1AJCA 4QH0A 5GKCA 3WAYA 4TN0A 3TX0A 2IUCA 5C66A 3OT9A 1ZEBA 1ED9A 5GKPA 3DPCA 4FDIA 1EW9A 4GTYA 2IFYA 1ANJA 4FDJA
chains in the Genus database with same CATH topology
1KHKA 3S5BA 1Y7AA 2W5QA 3NKPA 2QZUA 1FSUA 3E2DA 4QAXA 1KH4A 1KH7A 4A1NA 5LRNA 1SHNA 5IJSA 1ALIA 4GTXA 2IUCB 3ED4A 1QL0A 5AJ9A 4MHXA 1Y6VA 2W5WA 1ED8A 2O3BA 5EGHA 4YR1A 4UORA 1P49A 2W5SA 2ZKTA 5K4PA 1EQJA 3MK2A 4GTWA 4CYSA 1ALHA 3TWZA 1G8TA 1ELZA 4LRDA 2D1GA 4KJGA 4UPHA 3DYCA 3NVLA 3WBHA 2GSNA 4MY4A 2G9YA 3LXQA 3OWVA 2VQRA 2W5TA 1ZEFA 3IGYB 5GRRA 4CXUA 1ZM8A 2W8DA 2RH6A 4KJDA 3T01A 4CXKA 1QAEA 1N2LA 1B8JA 1K7HA 1URAA 3T02A 2GSUA 3B5QA 3CMRA 1KHJA 4QN0A 1AJAA 4LR2A 5LRMA 1HDHA 1KH9A 2GSOA 5DLTA 4MIVA 1E3CP 4QGOA 1SHQA 3UN2A 3WAWA 3M8ZA 1EI6A 4NWJA 4LR7A 3UN5A 2X98A 2W5XA 4UOPA 1ELXA 4KAVA 4KM4A 4GTZA 5L0KA 3UNYA 3WAVA 3MK1A 5LIAA 4LREA 4ZG6A 1E33P 3BDFA 3A52A 5TJ3A 3NKRA 4LRFA 3IDDA 1E2SP 1AJDA 5LQQA 1EW2A 1O98A 3KD8A 4LR8A 4NWXA 1ANIA 5GOVA 2ANHA 3BDGB 4ZG9A 1KH5A 4KAYA 2XH3A 2XGRA 2GLQA 5INHA 3UN3A 1HJKA 3M7VA 4CYRA 1KHNA 3T00A 3M8WA 4LR9A 5EGEA 1EW8A 3TG0A 1ZEDA 3NKMA 2XRGA 5IJQA 1O99A 4CXSA 1SMNA 4LRCA 5HRTA 1HQAA 4UOOA 5KXAA 3ISMA 5L0EA 1EJJA 3SZZA 4ZGAA 1KHLA 2GA3A 2XR9A 3Q3QA 4UPIA 3SZYA 1AJBA 3NKNA 5DLWA 4UPKA 4B56A 1URBA 3BDGA 4LQYA 4LRAA 1N2KA 4LRBA 3UO0A 5L0BA 3WAXA 3IGZB 1ALJA 3M8YA 4UPLA 3NKQA 4E3YA 2W5VA 2W8SA 4ZG7A 1ALKA 1E1ZP 3NKOA 5DLVA 2W5RA 1AUKA 3MK0A 4N7TA 1ELYA 3BDHA 1AJCA 4QH0A 5GKCA 3WAYA 4TN0A 3TX0A 2IUCA 5C66A 3OT9A 1ZEBA 1ED9A 5GKPA 3DPCA 4FDIA 1EW9A 4GTYA 2IFYA 1ANJA 4FDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KHK A;  3S5B A;  1Y7A A;  2W5Q A;  3NKP A;  2QZU A;  1FSU A;  3E2D A;  4QAX A;  1KH4 A;  1KH7 A;  4A1N A;  5LRN A;  1SHN A;  5IJS A;  1ALI A;  4GTX A;  2IUC B;  3ED4 A;  1QL0 A;  5AJ9 A;  4MHX A;  1Y6V A;  2W5W A;  1ED8 A;  2O3B A;  5EGH A;  4YR1 A;  4UOR A;  1P49 A;  2W5S A;  2ZKT A;  5K4P A;  1EQJ A;  3MK2 A;  4GTW A;  4CYS A;  1ALH A;  3TWZ A;  1G8T A;  1ELZ A;  4LRD A;  2D1G A;  4KJG A;  4UPH A;  3DYC A;  3NVL A;  3WBH A;  2GSN A;  4MY4 A;  2G9Y A;  3LXQ A;  3OWV A;  2VQR A;  2W5T A;  1ZEF A;  3IGY B;  5GRR A;  4CXU A;  1ZM8 A;  2W8D A;  2RH6 A;  4KJD A;  3T01 A;  4CXK A;  1QAE A;  1N2L A;  1B8J A;  1K7H A;  1URA A;  3T02 A;  2GSU A;  3B5Q A;  3CMR A;  1KHJ A;  4QN0 A;  1AJA A;  4LR2 A;  5LRM A;  1HDH A;  1KH9 A;  2GSO A;  5DLT A;  4MIV A;  1E3C P;  4QGO A;  1SHQ A;  3UN2 A;  3WAW A;  3M8Z A;  1EI6 A;  4NWJ A;  4LR7 A;  3UN5 A;  2X98 A;  2W5X A;  4UOP A;  1ELX A;  4KAV A;  4KM4 A;  4GTZ A;  5L0K A;  3UNY A;  3WAV A;  3MK1 A;  5LIA A;  4LRE A;  4ZG6 A;  1E33 P;  3BDF A;  3A52 A;  5TJ3 A;  3NKR A;  4LRF A;  3IDD A;  1E2S P;  1AJD A;  5LQQ A;  1EW2 A;  1O98 A;  3KD8 A;  4LR8 A;  4NWX A;  1ANI A;  5GOV A;  2ANH A;  3BDG B;  4ZG9 A;  1KH5 A;  4KAY A;  2XH3 A;  2XGR A;  2GLQ A;  5INH A;  3UN3 A;  1HJK A;  3M7V A;  4CYR A;  1KHN A;  3T00 A;  3M8W A;  4LR9 A;  5EGE A;  1EW8 A;  3TG0 A;  1ZED A;  3NKM A;  2XRG A;  5IJQ A;  1O99 A;  4CXS A;  1SMN A;  4LRC A;  5HRT A;  1HQA A;  4UOO A;  5KXA A;  3ISM A;  5L0E A;  1EJJ A;  3SZZ A;  4ZGA A;  1KHL A;  2GA3 A;  2XR9 A;  3Q3Q A;  4UPI A;  3SZY A;  1AJB A;  3NKN A;  5DLW A;  4UPK A;  4B56 A;  1URB A;  3BDG A;  4LQY A;  4LRA A;  1N2K A;  4LRB A;  3UO0 A;  5L0B A;  3WAX A;  3IGZ B;  1ALJ A;  3M8Y A;  4UPL A;  3NKQ A;  4E3Y A;  2W5V A;  2W8S A;  4ZG7 A;  1ALK A;  1E1Z P;  3NKO A;  5DLV A;  2W5R A;  1AUK A;  3MK0 A;  4N7T A;  1ELY A;  3BDH A;  1AJC A;  4QH0 A;  5GKC A;  3WAY A;  4TN0 A;  3TX0 A;  2IUC A;  5C66 A;  3OT9 A;  1ZEB A;  1ED9 A;  5GKP A;  3DPC A;  4FDI A;  1EW9 A;  4GTY A;  2IFY A;  1ANJ A;  4FDJ A; 
#chains in the Genus database with same CATH topology
 1KHK A;  3S5B A;  1Y7A A;  2W5Q A;  3NKP A;  2QZU A;  1FSU A;  3E2D A;  4QAX A;  1KH4 A;  1KH7 A;  4A1N A;  5LRN A;  1SHN A;  5IJS A;  1ALI A;  4GTX A;  2IUC B;  3ED4 A;  1QL0 A;  5AJ9 A;  4MHX A;  1Y6V A;  2W5W A;  1ED8 A;  2O3B A;  5EGH A;  4YR1 A;  4UOR A;  1P49 A;  2W5S A;  2ZKT A;  5K4P A;  1EQJ A;  3MK2 A;  4GTW A;  4CYS A;  1ALH A;  3TWZ A;  1G8T A;  1ELZ A;  4LRD A;  2D1G A;  4KJG A;  4UPH A;  3DYC A;  3NVL A;  3WBH A;  2GSN A;  4MY4 A;  2G9Y A;  3LXQ A;  3OWV A;  2VQR A;  2W5T A;  1ZEF A;  3IGY B;  5GRR A;  4CXU A;  1ZM8 A;  2W8D A;  2RH6 A;  4KJD A;  3T01 A;  4CXK A;  1QAE A;  1N2L A;  1B8J A;  1K7H A;  1URA A;  3T02 A;  2GSU A;  3B5Q A;  3CMR A;  1KHJ A;  4QN0 A;  1AJA A;  4LR2 A;  5LRM A;  1HDH A;  1KH9 A;  2GSO A;  5DLT A;  4MIV A;  1E3C P;  4QGO A;  1SHQ A;  3UN2 A;  3WAW A;  3M8Z A;  1EI6 A;  4NWJ A;  4LR7 A;  3UN5 A;  2X98 A;  2W5X A;  4UOP A;  1ELX A;  4KAV A;  4KM4 A;  4GTZ A;  5L0K A;  3UNY A;  3WAV A;  3MK1 A;  5LIA A;  4LRE A;  4ZG6 A;  1E33 P;  3BDF A;  3A52 A;  5TJ3 A;  3NKR A;  4LRF A;  3IDD A;  1E2S P;  1AJD A;  5LQQ A;  1EW2 A;  1O98 A;  3KD8 A;  4LR8 A;  4NWX A;  1ANI A;  5GOV A;  2ANH A;  3BDG B;  4ZG9 A;  1KH5 A;  4KAY A;  2XH3 A;  2XGR A;  2GLQ A;  5INH A;  3UN3 A;  1HJK A;  3M7V A;  4CYR A;  1KHN A;  3T00 A;  3M8W A;  4LR9 A;  5EGE A;  1EW8 A;  3TG0 A;  1ZED A;  3NKM A;  2XRG A;  5IJQ A;  1O99 A;  4CXS A;  1SMN A;  4LRC A;  5HRT A;  1HQA A;  4UOO A;  5KXA A;  3ISM A;  5L0E A;  1EJJ A;  3SZZ A;  4ZGA A;  1KHL A;  2GA3 A;  2XR9 A;  3Q3Q A;  4UPI A;  3SZY A;  1AJB A;  3NKN A;  5DLW A;  4UPK A;  4B56 A;  1URB A;  3BDG A;  4LQY A;  4LRA A;  1N2K A;  4LRB A;  3UO0 A;  5L0B A;  3WAX A;  3IGZ B;  1ALJ A;  3M8Y A;  4UPL A;  3NKQ A;  4E3Y A;  2W5V A;  2W8S A;  4ZG7 A;  1ALK A;  1E1Z P;  3NKO A;  5DLV A;  2W5R A;  1AUK A;  3MK0 A;  4N7T A;  1ELY A;  3BDH A;  1AJC A;  4QH0 A;  5GKC A;  3WAY A;  4TN0 A;  3TX0 A;  2IUC A;  5C66 A;  3OT9 A;  1ZEB A;  1ED9 A;  5GKP A;  3DPC A;  4FDI A;  1EW9 A;  4GTY A;  2IFY A;  1ANJ A;  4FDJ A; 
#chains in the Genus database with same CATH homology
 1KHK A;  3S5B A;  1Y7A A;  2W5Q A;  3NKP A;  2QZU A;  1FSU A;  3E2D A;  4QAX A;  1KH4 A;  1KH7 A;  4A1N A;  5LRN A;  1SHN A;  5IJS A;  1ALI A;  4GTX A;  2IUC B;  3ED4 A;  1QL0 A;  5AJ9 A;  4MHX A;  1Y6V A;  2W5W A;  1ED8 A;  2O3B A;  5EGH A;  4YR1 A;  4UOR A;  1P49 A;  2W5S A;  2ZKT A;  5K4P A;  1EQJ A;  3MK2 A;  4GTW A;  4CYS A;  1ALH A;  3TWZ A;  1G8T A;  1ELZ A;  4LRD A;  2D1G A;  4KJG A;  4UPH A;  3DYC A;  3NVL A;  3WBH A;  2GSN A;  4MY4 A;  2G9Y A;  3LXQ A;  3OWV A;  2VQR A;  2W5T A;  1ZEF A;  3IGY B;  5GRR A;  4CXU A;  1ZM8 A;  2W8D A;  2RH6 A;  4KJD A;  3T01 A;  4CXK A;  1QAE A;  1N2L A;  1B8J A;  1K7H A;  1URA A;  3T02 A;  2GSU A;  3B5Q A;  3CMR A;  1KHJ A;  4QN0 A;  1AJA A;  4LR2 A;  5LRM A;  1HDH A;  1KH9 A;  2GSO A;  5DLT A;  4MIV A;  1E3C P;  4QGO A;  1SHQ A;  3UN2 A;  3WAW A;  3M8Z A;  1EI6 A;  4NWJ A;  4LR7 A;  3UN5 A;  2X98 A;  2W5X A;  4UOP A;  1ELX A;  4KAV A;  4KM4 A;  4GTZ A;  5L0K A;  3UNY A;  3WAV A;  3MK1 A;  5LIA A;  4LRE A;  4ZG6 A;  1E33 P;  3BDF A;  3A52 A;  5TJ3 A;  3NKR A;  4LRF A;  3IDD A;  1E2S P;  1AJD A;  5LQQ A;  1EW2 A;  1O98 A;  3KD8 A;  4LR8 A;  4NWX A;  1ANI A;  5GOV A;  2ANH A;  3BDG B;  4ZG9 A;  1KH5 A;  4KAY A;  2XH3 A;  2XGR A;  2GLQ A;  5INH A;  3UN3 A;  1HJK A;  3M7V A;  4CYR A;  1KHN A;  3T00 A;  3M8W A;  4LR9 A;  5EGE A;  1EW8 A;  3TG0 A;  1ZED A;  3NKM A;  2XRG A;  5IJQ A;  1O99 A;  4CXS A;  1SMN A;  4LRC A;  5HRT A;  1HQA A;  4UOO A;  5KXA A;  3ISM A;  5L0E A;  1EJJ A;  3SZZ A;  4ZGA A;  1KHL A;  2GA3 A;  2XR9 A;  3Q3Q A;  4UPI A;  3SZY A;  1AJB A;  3NKN A;  5DLW A;  4UPK A;  4B56 A;  1URB A;  3BDG A;  4LQY A;  4LRA A;  1N2K A;  4LRB A;  3UO0 A;  5L0B A;  3WAX A;  3IGZ B;  1ALJ A;  3M8Y A;  4UPL A;  3NKQ A;  4E3Y A;  2W5V A;  2W8S A;  4ZG7 A;  1ALK A;  1E1Z P;  3NKO A;  5DLV A;  2W5R A;  1AUK A;  3MK0 A;  4N7T A;  1ELY A;  3BDH A;  1AJC A;  4QH0 A;  5GKC A;  3WAY A;  4TN0 A;  3TX0 A;  2IUC A;  5C66 A;  3OT9 A;  1ZEB A;  1ED9 A;  5GKP A;  3DPC A;  4FDI A;  1EW9 A;  4GTY A;  2IFY A;  1ANJ A;  4FDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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