5IQPA

14-3-3 protein tau isoform
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
230
structure length
230
Chain Sequence
MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein theta
total genus 94
structure length 230
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5iqpA00
4DHMA 3EFZA 3IQJA 5F74A 2BTPA 5D2DA 4N7YA 5D3FA 4DHPA 5J31A 1QJAA 3P1SA 3UX0A 5BTVA 1A37A 2O8PA 3LW1A 4DHSA 1IB1A 3U9XA 4DAUA 3CU8A 1QJBA 3O8IA 4E2EA 5BY9A 3P1RA 3SMOA 4DHQA 3M50A 1YWTA 2O02A 1O9DA 2C1NA 2C23A 3P1QA 5EWZA 3T0MA 2B05A 1A4OA 4BG6A 5HF3A 2V7DA 4N7GA 4DHRA 3UBWA 4Y5IA 4WRQA 5LU2A 2C74A 1O9CA 3T0LA 3SPRA 3SMLA 3AXYC 4FJ3A 3M51A 3UZDA 4O46A 4IHLA 3P1OA 2O98A 4ZQ0A 3P1PA 4GNTA 4JDDA 4IEAA 3MHRA 3NKXA 4F7RA 2C1JA 2BR9A 4DATA 5D3EA 3SMMA 3E6YA 4DHTA 2C63A 1O9EA 4FR3A 4J6SA 4ZDRA 4DHOA 4QLIA 1YZ5A 5LU1A 3SP5A 3RDHA 4DHNA 5LHOA 3SMNA 4N84A 4HKCA 4Y32A 4Y3BA 2BQ0A 4FL5A 1A38A 5IQPA 3IQVA 4DHUA 2WH0A 2NPMA 3UALA 4DNKA 1O9FA 5EXAA 3IQUA 5LX2A 4DX0A 3SMKA 3P1NA 5LVZA 4JC3A
chains in the Genus database with same CATH superfamily
4DHMA 3EFZA 2C9KA 3IQJA 5F74A 2BTPA 5D2DA 4N7YA 5D3FA 4DHPA 5J31A 1QJAA 3P1SA 3UX0A 4QX0A 5BTVA 1A37A 2O8PA 3LW1A 4DHSA 1IB1A 3CQGA 3U9XA 4DAUA 3CU8A 4D8MA 1CIYA 1QJBA 3O8IA 4E2EA 5BY9A 3P1RA 3SMOA 4DHQA 1JI6A 1W99A 3M50A 1YWTA 2O02A 1O9DA 2C1NA 2C23A 3P1QA 4ARXA 4QX2A 5EWZA 3T0MA 2B05A 1A4OA 1I5PA 4BG6A 5HF3A 2V7DA 1S2XA 4N7GA 4DHRA 3UBWA 4Y5IA 4WRQA 5LU2A 2C74A 4MOAA 1O9CA 3T0LA 4W8JA 3SPRA 3SMLA 3AXYC 3EB7A 4FJ3A 4QX3A 3M51A 3UZDA 4O46A 3I4RA 4IHLA 3P1OA 2O98A 4ZQ0A 3P1PA 4GNTA 1DLCA 4JDDA 4ARYA 4IEAA 3MHRA 3NKXA 4F7RA 2C1JA 2BR9A 4DATA 5D3EA 3SMMA 3E6YA 4DHTA 2C63A 1URJA 4QX1A 1O9EA 4FR3A 4J6SA 4ZDRA 4DHOA 4QLIA 1YZ5A 5LU1A 3SP5A 3RDHA 4DHNA 5LHOA 5LVZA 3SMNA 3CQCA 4N84A 4HKCA 4Y32A 4Y3BA 2BQ0A 4FL5A 1A38A 5IQPA 3IQVA 4DHUA 2WH0A 2NPMA 3UALA 3X0UA 4DNKA 1O9FA 5EXAA 3IQUA 5LX2A 4DX0A 3SMKA 3P1NA 3ZHEB 4JC3A
chains in the Genus database with same CATH topology
4DHMA 3EFZA 3IQJA 5F74A 2BTPA 5D2DA 4N7YA 5D3FA 4DHPA 5J31A 1QJAA 3P1SA 3UX0A 5BTVA 1A37A 2O8PA 3LW1A 4DHSA 1IB1A 3U9XA 4DAUA 3CU8A 1QJBA 3O8IA 4E2EA 5BY9A 3P1RA 3SMOA 4DHQA 3M50A 1YWTA 2O02A 1O9DA 2C1NA 2C23A 3P1QA 5EWZA 3T0MA 2B05A 1A4OA 4BG6A 5HF3A 2V7DA 4N7GA 4DHRA 3UBWA 4Y5IA 4WRQA 5LU2A 2C74A 1O9CA 3T0LA 3SPRA 3SMLA 3AXYC 4FJ3A 3M51A 3UZDA 4O46A 4IHLA 3P1OA 2O98A 4ZQ0A 3P1PA 4GNTA 4JDDA 4IEAA 3MHRA 3NKXA 4F7RA 2C1JA 2BR9A 4DATA 5D3EA 3SMMA 3E6YA 4DHTA 2C63A 1O9EA 4FR3A 4J6SA 4ZDRA 4DHOA 4QLIA 1YZ5A 5LU1A 3SP5A 3RDHA 4DHNA 5LHOA 3SMNA 4N84A 4HKCA 4Y32A 4Y3BA 2BQ0A 4FL5A 1A38A 5IQPA 3IQVA 4DHUA 2WH0A 2NPMA 3UALA 4DNKA 1O9FA 5EXAA 3IQUA 5LX2A 4DX0A 3SMKA 3P1NA 5LVZA 4JC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DHM A;  3EFZ A;  3IQJ A;  5F74 A;  2BTP A;  5D2D A;  4N7Y A;  5D3F A;  4DHP A;  5J31 A;  1QJA A;  3P1S A;  3UX0 A;  5BTV A;  1A37 A;  2O8P A;  3LW1 A;  4DHS A;  1IB1 A;  3U9X A;  4DAU A;  3CU8 A;  1QJB A;  3O8I A;  4E2E A;  5BY9 A;  3P1R A;  3SMO A;  4DHQ A;  3M50 A;  1YWT A;  2O02 A;  1O9D A;  2C1N A;  2C23 A;  3P1Q A;  5EWZ A;  3T0M A;  2B05 A;  1A4O A;  4BG6 A;  5HF3 A;  2V7D A;  4N7G A;  4DHR A;  3UBW A;  4Y5I A;  4WRQ A;  5LU2 A;  2C74 A;  1O9C A;  3T0L A;  3SPR A;  3SML A;  3AXY C;  4FJ3 A;  3M51 A;  3UZD A;  4O46 A;  4IHL A;  3P1O A;  2O98 A;  4ZQ0 A;  3P1P A;  4GNT A;  4JDD A;  4IEA A;  3MHR A;  3NKX A;  4F7R A;  2C1J A;  2BR9 A;  4DAT A;  5D3E A;  3SMM A;  3E6Y A;  4DHT A;  2C63 A;  1O9E A;  4FR3 A;  4J6S A;  4ZDR A;  4DHO A;  4QLI A;  1YZ5 A;  5LU1 A;  3SP5 A;  3RDH A;  4DHN A;  5LHO A;  3SMN A;  4N84 A;  4HKC A;  4Y32 A;  4Y3B A;  2BQ0 A;  4FL5 A;  1A38 A;  5IQP A;  3IQV A;  4DHU A;  2WH0 A;  2NPM A;  3UAL A;  4DNK A;  1O9F A;  5EXA A;  3IQU A;  5LX2 A;  4DX0 A;  3SMK A;  3P1N A;  5LVZ A;  4JC3 A; 
#chains in the Genus database with same CATH topology
 4DHM A;  3EFZ A;  2C9K A;  3IQJ A;  5F74 A;  2BTP A;  5D2D A;  4N7Y A;  5D3F A;  4DHP A;  5J31 A;  1QJA A;  3P1S A;  3UX0 A;  4QX0 A;  5BTV A;  1A37 A;  2O8P A;  3LW1 A;  4DHS A;  1IB1 A;  3CQG A;  3U9X A;  4DAU A;  3CU8 A;  4D8M A;  1CIY A;  1QJB A;  3O8I A;  4E2E A;  5BY9 A;  3P1R A;  3SMO A;  4DHQ A;  1JI6 A;  1W99 A;  3M50 A;  1YWT A;  2O02 A;  1O9D A;  2C1N A;  2C23 A;  3P1Q A;  4ARX A;  4QX2 A;  5EWZ A;  3T0M A;  2B05 A;  1A4O A;  1I5P A;  4BG6 A;  5HF3 A;  2V7D A;  1S2X A;  4N7G A;  4DHR A;  3UBW A;  4Y5I A;  4WRQ A;  5LU2 A;  2C74 A;  4MOA A;  1O9C A;  3T0L A;  4W8J A;  3SPR A;  3SML A;  3AXY C;  3EB7 A;  4FJ3 A;  4QX3 A;  3M51 A;  3UZD A;  4O46 A;  3I4R A;  4IHL A;  3P1O A;  2O98 A;  4ZQ0 A;  3P1P A;  4GNT A;  1DLC A;  4JDD A;  4ARY A;  4IEA A;  3MHR A;  3NKX A;  4F7R A;  2C1J A;  2BR9 A;  4DAT A;  5D3E A;  3SMM A;  3E6Y A;  4DHT A;  2C63 A;  1URJ A;  4QX1 A;  1O9E A;  4FR3 A;  4J6S A;  4ZDR A;  4DHO A;  4QLI A;  1YZ5 A;  5LU1 A;  3SP5 A;  3RDH A;  4DHN A;  5LHO A;  5LVZ A;  3SMN A;  3CQC A;  4N84 A;  4HKC A;  4Y32 A;  4Y3B A;  2BQ0 A;  4FL5 A;  1A38 A;  5IQP A;  3IQV A;  4DHU A;  2WH0 A;  2NPM A;  3UAL A;  3X0U A;  4DNK A;  1O9F A;  5EXA A;  3IQU A;  5LX2 A;  4DX0 A;  3SMK A;  3P1N A;  3ZHE B;  4JC3 A; 
#chains in the Genus database with same CATH homology
 4DHM A;  3EFZ A;  3IQJ A;  5F74 A;  2BTP A;  5D2D A;  4N7Y A;  5D3F A;  4DHP A;  5J31 A;  1QJA A;  3P1S A;  3UX0 A;  5BTV A;  1A37 A;  2O8P A;  3LW1 A;  4DHS A;  1IB1 A;  3U9X A;  4DAU A;  3CU8 A;  1QJB A;  3O8I A;  4E2E A;  5BY9 A;  3P1R A;  3SMO A;  4DHQ A;  3M50 A;  1YWT A;  2O02 A;  1O9D A;  2C1N A;  2C23 A;  3P1Q A;  5EWZ A;  3T0M A;  2B05 A;  1A4O A;  4BG6 A;  5HF3 A;  2V7D A;  4N7G A;  4DHR A;  3UBW A;  4Y5I A;  4WRQ A;  5LU2 A;  2C74 A;  1O9C A;  3T0L A;  3SPR A;  3SML A;  3AXY C;  4FJ3 A;  3M51 A;  3UZD A;  4O46 A;  4IHL A;  3P1O A;  2O98 A;  4ZQ0 A;  3P1P A;  4GNT A;  4JDD A;  4IEA A;  3MHR A;  3NKX A;  4F7R A;  2C1J A;  2BR9 A;  4DAT A;  5D3E A;  3SMM A;  3E6Y A;  4DHT A;  2C63 A;  1O9E A;  4FR3 A;  4J6S A;  4ZDR A;  4DHO A;  4QLI A;  1YZ5 A;  5LU1 A;  3SP5 A;  3RDH A;  4DHN A;  5LHO A;  3SMN A;  4N84 A;  4HKC A;  4Y32 A;  4Y3B A;  2BQ0 A;  4FL5 A;  1A38 A;  5IQP A;  3IQV A;  4DHU A;  2WH0 A;  2NPM A;  3UAL A;  4DNK A;  1O9F A;  5EXA A;  3IQU A;  5LX2 A;  4DX0 A;  3SMK A;  3P1N A;  5LVZ A;  4JC3 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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