5IRSA

Crystal structure of the proteasomal rpn13 pru-domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
110
structure length
110
Chain Sequence
KYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
pubmed doi rcsb
molecule keywords Proteasomal ubiquitin receptor ADRM1
molecule tags Protein binding
source organism Homo sapiens
total genus 29
structure length 110
sequence length 110
ec nomenclature
pdb deposition date 2016-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04683 Proteasom_Rpn13 Proteasome complex subunit Rpn13 ubiquitin receptor
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.70 Mainly Beta Roll PH-domain like PH-domain like 5irsA00
2Z4DA 5IRSA 2NBVA 2R2YA 2KR0A 2Z59A
chains in the Genus database with same CATH superfamily
2N23A 3SNHA 1X11A 3DXDA 5IRSA 1WGUA 1MK7B 2PZ1A 5EFXA 1OMWA 3U12A 1MKEA 2H7EA 4IAPA 3WYFB 4EKUA 5I2MA 4B6HA 2UZSA 3TCAA 4HAVB 3PVWA 1TQZA 2Z4DA 1PLSA 4L6EA 2DHJA 1XR0B 2RNRB 2UZRA 3ZDTA 2DKQA 3QWMA 1DDVA 3NSUA 3NWAA 1XD4A 4TYZA 2JP2A 2YF0A 5CLLB 2EC1A 1V5MA 2X18A 1WJ1A 2LOXA 1B55A 1W1DA 4ZRKA 1PMSA 2YT0A 1MAIA 1E5WA 2KCJA 2NBVA 2MWNB 1EVHA 1BTKA 2NZ8B 2W2XC 2H7DA 3V5WA 1DDWA 2DKPA 3TO1A 2ELBA 5LG4B 4K2PA 3ULBA 5JHGA 1XCGA 1TJ6A 2Z59A 3LJUX 3QBVB 4K17A 1UNQA 4GMVA 1FB8A 3BINA 4PQ0A 2BCJA 5HE3A 5JLJB 4WVFB 2MDXA 1WJMA 3N7CA 4NY0A 4ZRIA 3KRWA 1FOEA 2GUMA 5C16A 4OT1A 2LOZA 5C79A 2QKMA 4YONA 1AQCA 2D9XA 2OTXA 3PZDA 1UPRA 2LKOA 2RGNB 2VSZA 4L1RA 2KUPA 3HIEA 1H4RA 3FEHA 2RVBB 1UPQA 2I1KA 1OY2A 2D4QA 1SHCA 2D10A 2EMTA 3KY9A 4DX8A 4F7GA 3KSYA 4HB3B 1ZYIA 1M7RA 1ZC3B 5JP4A 5JHHA 2K2JA 2Y8GA 1EF1A 2R0DA 2J0MA 1NU2A 4HDQA 1SGHA 1Y5OA 2J0KA 1M7EA 4QXAB 1EGXA 1K5GB 2RLOA 2DYQA 1WI1A 3OHMB 4KAXB 4GZUA 1QQGA 4IOYX 2V76A 2ZKMX 1NI2A 4NSWA 5LOPB 5CLQB 3G9WA 3PSCA 1KZGA 1MK9B 1Q67A 3X23A 1I2HA 2L1CA 4K81A 1J0WA 2IFSA 1PFJA 5KCVA 4DX90 2K49A 2LYDA 4HAXB 3CXBB 1ZC4B 2E2XA 3PG7A 4XWXA 4A6FA 2P0HA 2RRFA 3DXCA 4KVGB 2UVMA 2KIGA 2FJUB 2CODA 2YVCA 3MDBC 1NTYA 2D9ZA 4Y94A 4A6FB 2J0JA 3SYXA 2KR0A 1TXDA 4F7UP 2G35A 1DBHA 3UZTA 2DX1A 3ML4A 3VOQA 4CHJA 4IFSA 1AWEA 2L2IA 3A8QA 2D9WA 3GYPA 3HW2B 2DHIA 3AU5A 1MIXA 3AJ4A 3TVVA 2ROVA 2ROZB 2VRWB 4HATB 4HB0B 4GOUA 2NMBA 2OQBA 2DHKA 3MPXA 1XX0A 2CRFA 2ADZA 4CYEA 1WVHA 2GCJA 5J3TA 1GC7A 1H10A 1FGYA 2YS3A 2W2XD 5I2SA 4HAWB 3P6AA 3TFMA 2D2QA 1X1FA 5KQ4A 2K2UA 3M1IB 4HAZB 2YS1A 4KHBB 1IRSA 2QKLA 2ELAA 5D3WA 2COFA 4EMOA 4HAUB 1UNRA 4HB4B 2EMSA 1W1HA 2R09A 3NW8A 2IYBA 4QJ3B 2DFKA 4WJ7A 2VKIA 1DROA 1EAZA 5D27A 3P7ZA 2YT1A 3IVFA 2P8VA 4WSFA 4PNKA 5C5BA 3BJIA 2P0FA 3KZ1A 5DI9B 3O96A 1BAKA 2MFQA 5C5BB 1ISNA 2R2YA 3SO6A 3D8DA 3KRXA 4CHMA 2KGXB 1UEFA 1U5DA 3ULCA 4A5KA 5C6RA 3B77A 2CY4A 2W2WA 5J3QA 3QIJA 2J59M 2GS0A 2YSZA 3NWDA 2DTCA 5J3YA 2HTHB 2Y7BA 2N0YA 3CIKA 1RRPB 1FGZA 2D9YA 1V88A 3PEGA 2I1JA 1FHWA 1FAOA 4GXBA 4YL8A 2YT2A 1DYNA 1DDMA 2COCA 5DHAB 4K2OA 4HAYB 3F5RA 3PVLA 4MY6A 1U5GA 3DCXA 5D3YA 5DIFB 1ZM0A 2EJ8A 1KZ7A 1U27A 2Z0QA 4A6HA 4DIXA 4OSNA 1WG7A 3ODXA 3TW1A 1P3RA 2CAYA 1J19A 2AL6A 2MKRA 2FJLA 1N3HA 3A8PA 5L81A 4Z2MB 2GCLA 2YS5A 4GMXB 3FVCA 2D11A 3F0WA 1GG3A 5FI0A 2KIEA 1RJ2A 4P7IA 3GYOA 4TKNA 1V5PA 4GPTB 3HK0A 1LW3A 4Z2NA 1U2BA 2Q13A 4MK0A 3SV1A 4GNKB 1KI1B 1X86A 1QC6A 2K00A 3T06A 4KHBA 4ZRJA 5LONB 1K5DB 2Z14A 3ODWA 1X1GA 2I5FA 2KUQA 2RSGA 5FI1A 2RUKB 1WGQA 1GC6A 3PVUA 4D6WA 1X05A 1BTNA 2DYNA 4KHAA 1U29A 3D8EA 2YRYA 1V61A 2COAA 3HSAA 2I5CA 2DLWA 3SUZA 3D8FA 3OANA 4DBBA 3AU4A 1UNPA 2HE7A 3PP2A 1FHOA 1BWNA 4DXAB 3A98B 3U8ZA 2DA0A 4HDOA 1XODA 5HE0A 4KHOA 4EJNA 4GN1A 1P6SA 5DHFB 2Z0PA 5HE1A 5D3VA 4C0AA 3FM8C 2CY5A 2AEHA 2ZPYA 2DX5A 1Z87A 1Y19B 1T77A 3HQCA 2K8EA 1NTVA 1U5EA 5D3XA 2GJYA 4H8SA 4A6KA 3ZVRA 2XQNM 1ZSQA 4HSIA 3NWFA 4BBKA 4QJ5B 3WA0A 1MIZB 1OQNA 2M14A 4MT7A 5GOWB 2M38A 2Z0OA 2DN6A 2P0DA 1MI1A 2Y8FA 2D9VA 1W1GA 2LULA 3VIAA 1U5FA 4D0NB 3DXEA 3FSSA 1MPHA 2Z13A 1XKEA 4CSQA 4F7HA 1LB1A 1ZVRA 5DH9B 1V5UA 3A58A 5HE2A 1I7AA 3U7DA 5M4YB 1P5TA 4HB2B 1V89A 3ODOA 4QJ4B 1FHXA 2LG1A 4HHVA 5KQ1A 3RCPA
chains in the Genus database with same CATH topology
4Z2NA 2KIGA 1ZYIA 3TW1A 2FJUB 4GOUA 2GUMA 2K8EA 3FSSA 3NWAA 3NW8A 4OT1A 5IRSA 2R2YA 2KR0A 2Z13A 4QJ3B 2GCJA 4GNKB 3TO1A 2YT2A 4CSQA 4KHBA 4Z2MB 3U12A 5LG4B 2GCLA 4HSIA 5I2SA 4QXAB 4IFSA 3FVCA 3NWFA 2Z14A 2Z59A 4QJ5B 3A58A 2K49A 2KUQA 4KHOA 4L1RA 3OHMB 3HIEA 5M4YB 5I2MA 3NWDA 3GYPA 4IOYX 4D6WA 2KIEA 2RRFA 2ZKMX 2Z4DA 3GYOA 4KHBB 4KHAA 3TVVA 4QJ4B 4PQ0A 2NBVA 4DIXA 4OSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z4D A;  5IRS A;  2NBV A;  2R2Y A;  2KR0 A;  2Z59 A; 
#chains in the Genus database with same CATH topology
 2N23 A;  3SNH A;  1X11 A;  3DXD A;  5IRS A;  1WGU A;  1MK7 B;  2PZ1 A;  5EFX A;  1OMW A;  3U12 A;  1MKE A;  2H7E A;  4IAP A;  3WYF B;  4EKU A;  5I2M A;  4B6H A;  2UZS A;  3TCA A;  4HAV B;  3PVW A;  1TQZ A;  2Z4D A;  1PLS A;  4L6E A;  2DHJ A;  1XR0 B;  2RNR B;  2UZR A;  3ZDT A;  2DKQ A;  3QWM A;  1DDV A;  3NSU A;  3NWA A;  1XD4 A;  4TYZ A;  2JP2 A;  2YF0 A;  5CLL B;  2EC1 A;  1V5M A;  2X18 A;  1WJ1 A;  2LOX A;  1B55 A;  1W1D A;  4ZRK A;  1PMS A;  2YT0 A;  1MAI A;  1E5W A;  2KCJ A;  2NBV A;  2MWN B;  1EVH A;  1BTK A;  2NZ8 B;  2W2X C;  2H7D A;  3V5W A;  1DDW A;  2DKP A;  3TO1 A;  2ELB A;  5LG4 B;  4K2P A;  3ULB A;  5JHG A;  1XCG A;  1TJ6 A;  2Z59 A;  3LJU X;  3QBV B;  4K17 A;  1UNQ A;  4GMV A;  1FB8 A;  3BIN A;  4PQ0 A;  2BCJ A;  5HE3 A;  5JLJ B;  4WVF B;  2MDX A;  1WJM A;  3N7C A;  4NY0 A;  4ZRI A;  3KRW A;  1FOE A;  2GUM A;  5C16 A;  4OT1 A;  2LOZ A;  5C79 A;  2QKM A;  4YON A;  1AQC A;  2D9X A;  2OTX A;  3PZD A;  1UPR A;  2LKO A;  2RGN B;  2VSZ A;  4L1R A;  2KUP A;  3HIE A;  1H4R A;  3FEH A;  2RVB B;  1UPQ A;  2I1K A;  1OY2 A;  2D4Q A;  1SHC A;  2D10 A;  2EMT A;  3KY9 A;  4DX8 A;  4F7G A;  3KSY A;  4HB3 B;  1ZYI A;  1M7R A;  1ZC3 B;  5JP4 A;  5JHH A;  2K2J A;  2Y8G A;  1EF1 A;  2R0D A;  2J0M A;  1NU2 A;  4HDQ A;  1SGH A;  1Y5O A;  2J0K A;  1M7E A;  4QXA B;  1EGX A;  1K5G B;  2RLO A;  2DYQ A;  1WI1 A;  3OHM B;  4KAX B;  4GZU A;  1QQG A;  4IOY X;  2V76 A;  2ZKM X;  1NI2 A;  4NSW A;  5LOP B;  5CLQ B;  3G9W A;  3PSC A;  1KZG A;  1MK9 B;  1Q67 A;  3X23 A;  1I2H A;  2L1C A;  4K81 A;  1J0W A;  2IFS A;  1PFJ A;  5KCV A;  4DX9 0;  2K49 A;  2LYD A;  4HAX B;  3CXB B;  1ZC4 B;  2E2X A;  3PG7 A;  4XWX A;  4A6F A;  2P0H A;  2RRF A;  3DXC A;  4KVG B;  2UVM A;  2KIG A;  2FJU B;  2COD A;  2YVC A;  3MDB C;  1NTY A;  2D9Z A;  4Y94 A;  4A6F B;  2J0J A;  3SYX A;  2KR0 A;  1TXD A;  4F7U P;  2G35 A;  1DBH A;  3UZT A;  2DX1 A;  3ML4 A;  3VOQ A;  4CHJ A;  4IFS A;  1AWE A;  2L2I A;  3A8Q A;  2D9W A;  3GYP A;  3HW2 B;  2DHI A;  3AU5 A;  1MIX A;  3AJ4 A;  3TVV A;  2ROV A;  2ROZ B;  2VRW B;  4HAT B;  4HB0 B;  4GOU A;  2NMB A;  2OQB A;  2DHK A;  3MPX A;  1XX0 A;  2CRF A;  2ADZ A;  4CYE A;  1WVH A;  2GCJ A;  5J3T A;  1GC7 A;  1H10 A;  1FGY A;  2YS3 A;  2W2X D;  5I2S A;  4HAW B;  3P6A A;  3TFM A;  2D2Q A;  1X1F A;  5KQ4 A;  2K2U A;  3M1I B;  4HAZ B;  2YS1 A;  4KHB B;  1IRS A;  2QKL A;  2ELA A;  5D3W A;  2COF A;  4EMO A;  4HAU B;  1UNR A;  4HB4 B;  2EMS A;  1W1H A;  2R09 A;  3NW8 A;  2IYB A;  4QJ3 B;  2DFK A;  4WJ7 A;  2VKI A;  1DRO A;  1EAZ A;  5D27 A;  3P7Z A;  2YT1 A;  3IVF A;  2P8V A;  4WSF A;  4PNK A;  5C5B A;  3BJI A;  2P0F A;  3KZ1 A;  5DI9 B;  3O96 A;  1BAK A;  2MFQ A;  5C5B B;  1ISN A;  2R2Y A;  3SO6 A;  3D8D A;  3KRX A;  4CHM A;  2KGX B;  1UEF A;  1U5D A;  3ULC A;  4A5K A;  5C6R A;  3B77 A;  2CY4 A;  2W2W A;  5J3Q A;  3QIJ A;  2J59 M;  2GS0 A;  2YSZ A;  3NWD A;  2DTC A;  5J3Y A;  2HTH B;  2Y7B A;  2N0Y A;  3CIK A;  1RRP B;  1FGZ A;  2D9Y A;  1V88 A;  3PEG A;  2I1J A;  1FHW A;  1FAO A;  4GXB A;  4YL8 A;  2YT2 A;  1DYN A;  1DDM A;  2COC A;  5DHA B;  4K2O A;  4HAY B;  3F5R A;  3PVL A;  4MY6 A;  1U5G A;  3DCX A;  5D3Y A;  5DIF B;  1ZM0 A;  2EJ8 A;  1KZ7 A;  1U27 A;  2Z0Q A;  4A6H A;  4DIX A;  4OSN A;  1WG7 A;  3ODX A;  3TW1 A;  1P3R A;  2CAY A;  1J19 A;  2AL6 A;  2MKR A;  2FJL A;  1N3H A;  3A8P A;  5L81 A;  4Z2M B;  2GCL A;  2YS5 A;  4GMX B;  3FVC A;  2D11 A;  3F0W A;  1GG3 A;  5FI0 A;  2KIE A;  1RJ2 A;  4P7I A;  3GYO A;  4TKN A;  1V5P A;  4GPT B;  3HK0 A;  1LW3 A;  4Z2N A;  1U2B A;  2Q13 A;  4MK0 A;  3SV1 A;  4GNK B;  1KI1 B;  1X86 A;  1QC6 A;  2K00 A;  3T06 A;  4KHB A;  4ZRJ A;  5LON B;  1K5D B;  2Z14 A;  3ODW A;  1X1G A;  2I5F A;  2KUQ A;  2RSG A;  5FI1 A;  2RUK B;  1WGQ A;  1GC6 A;  3PVU A;  4D6W A;  1X05 A;  1BTN A;  2DYN A;  4KHA A;  1U29 A;  3D8E A;  2YRY A;  1V61 A;  2COA A;  3HSA A;  2I5C A;  2DLW A;  3SUZ A;  3D8F A;  3OAN A;  4DBB A;  3AU4 A;  1UNP A;  2HE7 A;  3PP2 A;  1FHO A;  1BWN A;  4DXA B;  3A98 B;  3U8Z A;  2DA0 A;  4HDO A;  1XOD A;  5HE0 A;  4KHO A;  4EJN A;  4GN1 A;  1P6S A;  5DHF B;  2Z0P A;  5HE1 A;  5D3V A;  4C0A A;  3FM8 C;  2CY5 A;  2AEH A;  2ZPY A;  2DX5 A;  1Z87 A;  1Y19 B;  1T77 A;  3HQC A;  2K8E A;  1NTV A;  1U5E A;  5D3X A;  2GJY A;  4H8S A;  4A6K A;  3ZVR A;  2XQN M;  1ZSQ A;  4HSI A;  3NWF A;  4BBK A;  4QJ5 B;  3WA0 A;  1MIZ B;  1OQN A;  2M14 A;  4MT7 A;  5GOW B;  2M38 A;  2Z0O A;  2DN6 A;  2P0D A;  1MI1 A;  2Y8F A;  2D9V A;  1W1G A;  2LUL A;  3VIA A;  1U5F A;  4D0N B;  3DXE A;  3FSS A;  1MPH A;  2Z13 A;  1XKE A;  4CSQ A;  4F7H A;  1LB1 A;  1ZVR A;  5DH9 B;  1V5U A;  3A58 A;  5HE2 A;  1I7A A;  3U7D A;  5M4Y B;  1P5T A;  4HB2 B;  1V89 A;  3ODO A;  4QJ4 B;  1FHX A;  2LG1 A;  4HHV A;  5KQ1 A;  3RCP A; 
#chains in the Genus database with same CATH homology
 4Z2N A;  2KIG A;  1ZYI A;  3TW1 A;  2FJU B;  4GOU A;  2GUM A;  2K8E A;  3FSS A;  3NWA A;  3NW8 A;  4OT1 A;  5IRS A;  2R2Y A;  2KR0 A;  2Z13 A;  4QJ3 B;  2GCJ A;  4GNK B;  3TO1 A;  2YT2 A;  4CSQ A;  4KHB A;  4Z2M B;  3U12 A;  5LG4 B;  2GCL A;  4HSI A;  5I2S A;  4QXA B;  4IFS A;  3FVC A;  3NWF A;  2Z14 A;  2Z59 A;  4QJ5 B;  3A58 A;  2K49 A;  2KUQ A;  4KHO A;  4L1R A;  3OHM B;  3HIE A;  5M4Y B;  5I2M A;  3NWD A;  3GYP A;  4IOY X;  4D6W A;  2KIE A;  2RRF A;  2ZKM X;  2Z4D A;  3GYO A;  4KHB B;  4KHA A;  3TVV A;  4QJ4 B;  4PQ0 A;  2NBV A;  4DIX A;  4OSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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