5IYBC

Human core-pic in the open state
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
275
structure length
275
Chain Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase II subunit RPB1
publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transcription, transferase/dna
total genus 58
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 5iybC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 5iybC01
4Y52C 1I6HC 4NOIA 2JA8C 4KN7A 5M5YK 4A3MK 2A68A 4AYBL 4A3GK 1Y1WK 2R93K 3GTQK 5IP7C 4A3CC 5IYCC 3HOYC 4BY1K 3H3VL 3S2HK 1K83C 1IW7A 4A3EK 4QJVB 2NVXC 3HOZC 1I3QC 3DXJA 4A3LK 3K7AC 4QJVA 5C4XK 4A3MC 3GTJK 3HOZK 1I50K 4A3BK 4YFKA 5C4JC 4AYBD 1Y1WC 4OINA 4BY1C 3H3VD 2JA8K 3S2HC 4A3DC 2E2IC 3PO2K 2NVTC 3CQZC 4Y7NC 3RZOK 2R7ZK 2YU9K 4A3LC 3S2DC 2Y0SL 3HOYK 3S14K 4A3CK 4A3IK 2PA8D 5C4XC 3I4NK 2B63K 3GTJC 1I50C 2NVXK 1I3QK 3K7AK 2BE5A 4YFXA 3FKIC 2WB1L 3PO2C 3HOXC 2E2HC 5C4JK 3RZOC 2R7ZC 4LLGA 2YU9C 2Y0SD 4G7HA 3I4MC 3S14C 1WCMK 4A3IC 4A3DK 3I4NC 2E2IK 2B63C 2NVTK 5TMFA 3CQZK 4Y7NK 5M3FK 3PO3K 4OIQA 3S2DK 1YNNA 5IYBK 2PA8L 2JA7C 2E2JK 3M3YK 2R92C 2WB1D 4Q4ZA 3S17C 4LK0A 2JA6C 1HQMA 4XSXA 5TMCA 2JA5C 4BXXK 4MEXA 1WCMC 3FKIK 2A6HA 3S16C 4C2MC 3HOXK 3S1RK 2E2HK 3PO3C 4XSZA 3I4MK 2CW0A 3WODA 4MQ9A 5IYBC 2E2JC 3M3YC 3S1NC 4X6AK 4OIOA 1Y1VK 2O5JA 3GTMK 2JA7K 4A93K 1TWAK 2R92K 2PPBA 3HOVK 3S17K 2JA6K 3RZDK 3S1RC 2JA5K 4Q5SA 3GTGC 3S16K 4C2MK 4X6AC 1XPPA 4G7ZA 2NVQK 1Y1VC 2PMZL 1ZYRA 3GTMC 4A3JC 1TWFK 3H0GK 4A93C 1TWAC 3S1NK 3HOVC 1YNJA 1R9TK 4XLNA 3M4OK 3RZDC 5C44K 5C3EC 4C3IK 4YFNA 4A3FK 1TWHK 1TWGC 1I6VA 2NVQC 4A3KK 5IYDC 3GTPK 2PMZD 3GTGK 4C3HK 4KMUA 1TWFC 3H0GC 5FLMK 3HOUK 3HKZL 4QIWL 4KN4A 1SFOC 1R9TC 3M4OC 5C44C 2WAQL 4BBSK 4C3IC 4A3FC 4A3JK 4BY7C 4ZH4A 5M5WK 2VUMC 1TWHC 4OIPA 1TWCK 1BDFA 3S1QC 5IP9C 5M5XK 4A3KC 3GTPC 4G7OA 5C3EK 3GTOK 3HOWK 3S1MK 3GTKK 2A69A 3GTLK 4MEYA 4C3HC 2O5IA 5FLMC 3HOUC 5D4DA 3HKZD 3EQLA 4LJZA 4QIWD 4OIRA 4GZYA 1TWGK 2NVYK 4BBRK 4C3JK 2WAQD 4BBSC 4YG2A 3GTQC 4A3GC 2R93C 3S15K 4Y52K 1I6HK 4A3EC 4BXXC 1TWCC 1SFOK 3GTOC 3S1MC 3HOWC 4XLPA 5IP7K 2A6EA 4JK1A 3GTKC 4LK1A 3GTLC 1K83K 5IYCK 4BY7K 5FJ8K 2VUMK 1SMYA 3S1QK 5IYDK 4BBRC 5IP9K 2NVYC 3S15C 4C3JC 4A3BC 5M3MK
chains in the Genus database with same CATH superfamily
4GTCA 3GTQK 4A3CC 3HOYC 4A3EK 1O27A 1I3QC 2XCOA 4QJVA 1YCLA 3GTPA 4GTBA 4A3MC 3GTGA 1PJ5A 3V4GA 4A3BK 5HL8A 3H3VD 2JA8K 3S2HC 4KM9A 3PO2K 1O2FB 1TWAA 2YU9K 3S2DC 1AB4A 3I4NK 1I50C 3K7AK 2BE5A 1TWFA 3SZZA 5C4JK 3RZOC 2R7ZC 4LLGA 2Y0SD 3OPFA 1R9TA 1O24A 4IOAS 4OIQA 4WFNS 2PA8L 3JSTA 5IYBK 3ERED 2WB1D 3S17C 3AH5A 5CJ9A 1L0WA 4XSXA 4MEXA 1WCMC 4O2DA 3S16C 4C45A 3G4CA 3PO3C 3I4MK 2E2JC 4MQ9A 3M3YC 3TFHA 4KMDA 2NVYA 3AD9C 1I50A 1VH2A 2JA6K 1XXAA 2JA5K 2GAHC 4X6AC 2GSUA 2R7ZA 1Y1VC 1K83A 5DM6S 1GE9A 3GDZA 3GTMC 1EQRA 4A93C 1YNJA 4XLNA 3RZDC 5C3EC 4C3IK 2GSNA 4PAAA 1WQGA 1TWHK 3GTPK 4DDQA 3GTGK 2E2IA 4C3HK 4RMFA 3A8KA 1J6WA 5IOTA 2WAQL 4A3FC 4IOCS 4BXXK 2VUMC 5IP9C 3FKIA 3GEEA 1FEUA 3GTKK 2CFAA 3TFIA 3HOUC 2E2HA 3EQLA 4LJZA 3S15K 4BBSC 4YG2A 1XZQB 1Y1VA 3G4AA 2KWAA 2Y3PA 3S1MC 3T00A 4XLPA 2R92A 3AQPA 5M3MK 4C3JC 2EBBA 4NOIA 4KN7A 1V5VA 5M5YK 2KPUA 4A3MK 4AYBL 1IS1A 4A3GK 3S2HK 1DCHA 4QJVB 1EI6A 1WOPA 4LR2A 2NVXC 3DXJA 4KB2A 3N3YA 4PABA 1O28A 3FOEA 1I50K 1XXBA 1Y1WC 4OINA 4BY1C 2KQ1A 3GIRA 1J6XA 2NVTC 4U67S 3CQZC 5CHPA 2R7ZK 3RZOK 2PA8D 5JFEA 1XZPA 4IO9S 1IE0A 4J3NA 2FQOA 1F9NA 1WCMK 4GTEA 1SFOA 1PJ7A 4M1XA 4A3DK 2E2IK 2B63C 1ISEA 1PJ6A 4Y7NK 3PO3K 1TWHA 2E2JK 2JA7C 3M3YK 4WJ3M 4Q4ZA 1HI9A 3FKIK 3OEPA 2R93A 4G0UA 1Y1WA 1DCPA 3HOXK 2E2HK 1ZBSA 4XSZA 3LAPA 2CW0A 4KMAA 4X6AK 3S1NC 3GTKA 4OIOA 1Y1VK 4KAWX 3GTMK 1DD5A 4A93K 2R92K 1VLOA 3RZDK 3S1RC 4Q5SA 4C2MK 1XPPA 4G7ZA 1J6VA 2PMZL 4A3JC 3HOVC 1I3QA 5L46A 2ZUFA 4A3FK 3Q3QA 1TWGC 2NVQC 5IYDC 3A8IA 1KQ4A 3HOUK 3HKZL 3SZYA 2ZJQS 3M4OC 1WOSA 5C44C 4BBSK 2FQTA 4ZH4A 5M5WK 3AD8C 1BDFA 3S1QC 3S1MK 4A3KC 3CAGA 2A69A 2O5IA 4QIWD 4OIRA 3GEIA 2XCRB 4C3JK 3GTQC 1VGXA 1WOOA 4A3EC 1SFOK 3GTOC 3HOWC 4JK1A 3GTLC 4BY7K 2RH6A 4BLAA 1SMYA 1EK8A 1WCMA 4A3BC 2L5NA 4GTAA 3QX3A 4Y52C 1I6HC 2JA8C 3ADAC 1BS2A 1C0AA 1Y1WK 2R93K 3FHZA 5IP7C 4BY1K 2ZJPS 3H3VL 1WQHA 5IOQA 5TJ3A 1WSVA 1G51A 3HOZC 3IPJA 3K7AC 3VA7A 4WILA 4YFKA 5C4JC 1B4AA 2ZJRS 3GTMA 1XXCA 4A3CK 4A3LC 2Y0SL 3HOYK 1XZPB 3N0CA 5C4XC 2B63K 4P5AA 3GTJC 3GTLA 1I3QK 4GFQA 2WB1L 1IBAA 1JOEA 1X31C 1UV7A 2XCQA 3S14C 3I4MC 4A3IC 5TMFA 2ZUEA 5M3FK 2V6UA 3OREA 2VUMA 3S2DK 1YNNA 5HQHA 4WJ4A 2JA6C 1HQMA 5JVHS 2JA5C 2L3UA 2A6HA 5HL7S 3DLLS 3S1RK 1B4BA 3WODA 3CF5S 4XCHA 5E68A 1JVIA 3BP8C 3N0BA 1WIHA 3GTJA 3HOVK 3S17K 2PHCB 4P5BA 3GTGC 3S16K 2NVQK 1ZYRA 4G0WA 3MMLB 2NVXA 1TWAC 3M4OK 5C44K 4FZBA 5IOSA 2W7VA 1I6VA 1ZXOA 1USMA 4A3KK 1BGWA 4ILDA 4KMUA 1TWFC 3H0GC 3PIPS 1EH1A 3CQZA 4KN4A 1O2AA 1R9TC 3BP3A 3L4JA 5M5XK 2D6FC 3GTOK 5C3EK 3HOWK 3GTLK 4MEYA 4KATA 5FLMC 5JVOA 5D4DA 4GZYA 2WAQD 4A3GC 2B63A 1I6HK 4Y52K 2GSOA 5EGEA 2V6TA 1TWCC 5JVGS 3S0XA 2V6SA 4KC6A 2JA7A 5IP7K 3FOFA 2A6EA 4GTFA 4LK1A 1YX2A 2ZFZA 2VUMK 4BBRC 5IP9K 2NVYC 3GSIA 3HOZK 2P8TA 4KARA 2A68A 3H0GA 5DM7S 5IYCC 1K83C 1IW7A 1JQWA 1DCOA 2CFAB 1IL2A 1O2BA 4WFBS 4A3LK 3LPXA 5C4XK 1ZVUA 3GTJK 1O25A 4AYBD 4A3DC 2P5MA 2E2IC 4Y7NC 3S14K 1TWCA 4A3IK 1O26A 3AQOA 3HXAA 1INNA 2NVXK 4YFXA 1TWGA 3FKIC 4KDDA 3PO2C 3HOXC 2E2HC 2YU9C 4G7HA 4AH6A 4WF9S 3BUEA 3I4NC 2NVTK 3CQZK 1O29A 3A8JA 1WORA 2R92C 4LK0A 2GAGC 5TMCA 2KXYA 4C2MC 3GTQA 1BJTA 3TTGA 3GTOA 5IYBC 1USOA 4KB4A 2O5JA 4KM8A 1WSRA 1RU0A 2JA7K 1TWAK 3T01A 2PPBA 3L4KA 4G0VA 1ZQ1C 4BLBA 2YU9A 1VJEA 1TWFK 3H0GK 3S1NK 4BKWA 3LAJA 1R9TK 3TFJA 4YFNA 1F7UA 4KASA 2JH3A 1F93A 1IQ0A 3PIOS 2PMZD 1EFWA 5FLMK 1F7VA 4QIWL 1SFOC 4C3IC 1J98A 3GEHA 4BY7C 4A3JK 4GT9A 1TWCK 1TWHC 4OIPA 3NUHA 2RGRA 3GTPC 4G7OA 3AD7C 4P9SA 4LOWA 4C3HC 3HKZD 1TWGK 4BBRK 5FJ8K 5IYDK 2NVYK 4GTLA 2R93C 3LYWA 4GTDA 4BXXC 4WCES 1XZQA 4LQYA 5IYCK 3GTKC 2JA6A 1K83K 5IORA 5EGHA 1WQFA 2JA5A 4WFAS 3T02A 3S1QK 4KMHA 4FM9A 3S15C 1VRQC
chains in the Genus database with same CATH topology
4Y52C 1I6HC 4NOIA 2JA8C 4KN7A 5M5YK 4A3MK 2A68A 4AYBL 4A3GK 1Y1WK 2R93K 3GTQK 5IP7C 4A3CC 5IYCC 3HOYC 4BY1K 3H3VL 3S2HK 1K83C 1IW7A 4A3EK 4QJVB 2NVXC 3HOZC 1I3QC 3DXJA 4A3LK 3K7AC 4QJVA 5C4XK 4A3MC 3GTJK 3HOZK 1I50K 4A3BK 4YFKA 5C4JC 4AYBD 1Y1WC 4OINA 4BY1C 3H3VD 2JA8K 3S2HC 4A3DC 2E2IC 3PO2K 2NVTC 3CQZC 4Y7NC 3RZOK 2R7ZK 2YU9K 4A3LC 3S2DC 2Y0SL 3HOYK 3S14K 4A3CK 4A3IK 2PA8D 5C4XC 3I4NK 2B63K 3GTJC 1I50C 2NVXK 1I3QK 3K7AK 2BE5A 4YFXA 3FKIC 2WB1L 3PO2C 3HOXC 2E2HC 5C4JK 3RZOC 2R7ZC 4LLGA 2YU9C 2Y0SD 4G7HA 3I4MC 3S14C 1WCMK 4A3IC 4A3DK 3I4NC 2E2IK 2B63C 2NVTK 5TMFA 3CQZK 4Y7NK 5M3FK 3PO3K 4OIQA 3S2DK 1YNNA 5IYBK 2PA8L 2JA7C 2E2JK 3M3YK 2R92C 2WB1D 4Q4ZA 3S17C 4LK0A 2JA6C 1HQMA 4XSXA 5TMCA 2JA5C 4BXXK 4MEXA 1WCMC 3FKIK 2A6HA 3S16C 4C2MC 3HOXK 3S1RK 2E2HK 3PO3C 4XSZA 3I4MK 2CW0A 3WODA 4MQ9A 5IYBC 2E2JC 3M3YC 3S1NC 4X6AK 4OIOA 1Y1VK 2O5JA 3GTMK 2JA7K 4A93K 1TWAK 2R92K 2PPBA 3HOVK 3S17K 2JA6K 3RZDK 3S1RC 2JA5K 4Q5SA 3GTGC 3S16K 4C2MK 4X6AC 1XPPA 4G7ZA 2NVQK 1Y1VC 2PMZL 1ZYRA 3GTMC 4A3JC 1TWFK 3H0GK 4A93C 1TWAC 3S1NK 3HOVC 1YNJA 1R9TK 4XLNA 3M4OK 3RZDC 5C44K 5C3EC 4C3IK 4YFNA 4A3FK 1TWHK 1TWGC 1I6VA 2NVQC 4A3KK 5IYDC 3GTPK 2PMZD 3GTGK 4C3HK 4KMUA 1TWFC 3H0GC 5FLMK 3HOUK 3HKZL 4QIWL 4KN4A 1SFOC 1R9TC 3M4OC 5C44C 2WAQL 4BBSK 4C3IC 4A3FC 4A3JK 4BY7C 4ZH4A 5M5WK 2VUMC 1TWHC 4OIPA 1TWCK 1BDFA 3S1QC 5IP9C 5M5XK 4A3KC 3GTPC 4G7OA 5C3EK 3GTOK 3HOWK 3S1MK 3GTKK 2A69A 3GTLK 4MEYA 4C3HC 2O5IA 5FLMC 3HOUC 5D4DA 3HKZD 3EQLA 4LJZA 4QIWD 4OIRA 4GZYA 1TWGK 2NVYK 4BBRK 4C3JK 2WAQD 4BBSC 4YG2A 3GTQC 4A3GC 2R93C 3S15K 4Y52K 1I6HK 4A3EC 4BXXC 1TWCC 1SFOK 3GTOC 3S1MC 3HOWC 4XLPA 5IP7K 2A6EA 4JK1A 3GTKC 4LK1A 3GTLC 1K83K 5IYCK 4BY7K 5FJ8K 2VUMK 1SMYA 3S1QK 5IYDK 4BBRC 5IP9K 2NVYC 3S15C 4C3JC 4A3BC 5M3MK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y52 C;  1I6H C;  4NOI A;  2JA8 C;  4KN7 A;  5M5Y K;  4A3M K;  2A68 A;  4AYB L;  4A3G K;  1Y1W K;  2R93 K;  3GTQ K;  5IP7 C;  4A3C C;  5IYC C;  3HOY C;  4BY1 K;  3H3V L;  3S2H K;  1K83 C;  1IW7 A;  4A3E K;  4QJV B;  2NVX C;  3HOZ C;  1I3Q C;  3DXJ A;  4A3L K;  3K7A C;  4QJV A;  5C4X K;  4A3M C;  3GTJ K;  3HOZ K;  1I50 K;  4A3B K;  4YFK A;  5C4J C;  4AYB D;  1Y1W C;  4OIN A;  4BY1 C;  3H3V D;  2JA8 K;  3S2H C;  4A3D C;  2E2I C;  3PO2 K;  2NVT C;  3CQZ C;  4Y7N C;  3RZO K;  2R7Z K;  2YU9 K;  4A3L C;  3S2D C;  2Y0S L;  3HOY K;  3S14 K;  4A3C K;  4A3I K;  2PA8 D;  5C4X C;  3I4N K;  2B63 K;  3GTJ C;  1I50 C;  2NVX K;  1I3Q K;  3K7A K;  2BE5 A;  4YFX A;  3FKI C;  2WB1 L;  3PO2 C;  3HOX C;  2E2H C;  5C4J K;  3RZO C;  2R7Z C;  4LLG A;  2YU9 C;  2Y0S D;  4G7H A;  3I4M C;  3S14 C;  1WCM K;  4A3I C;  4A3D K;  3I4N C;  2E2I K;  2B63 C;  2NVT K;  5TMF A;  3CQZ K;  4Y7N K;  5M3F K;  3PO3 K;  4OIQ A;  3S2D K;  1YNN A;  5IYB K;  2PA8 L;  2JA7 C;  2E2J K;  3M3Y K;  2R92 C;  2WB1 D;  4Q4Z A;  3S17 C;  4LK0 A;  2JA6 C;  1HQM A;  4XSX A;  5TMC A;  2JA5 C;  4BXX K;  4MEX A;  1WCM C;  3FKI K;  2A6H A;  3S16 C;  4C2M C;  3HOX K;  3S1R K;  2E2H K;  3PO3 C;  4XSZ A;  3I4M K;  2CW0 A;  3WOD A;  4MQ9 A;  5IYB C;  2E2J C;  3M3Y C;  3S1N C;  4X6A K;  4OIO A;  1Y1V K;  2O5J A;  3GTM K;  2JA7 K;  4A93 K;  1TWA K;  2R92 K;  2PPB A;  3HOV K;  3S17 K;  2JA6 K;  3RZD K;  3S1R C;  2JA5 K;  4Q5S A;  3GTG C;  3S16 K;  4C2M K;  4X6A C;  1XPP A;  4G7Z A;  2NVQ K;  1Y1V C;  2PMZ L;  1ZYR A;  3GTM C;  4A3J C;  1TWF K;  3H0G K;  4A93 C;  1TWA C;  3S1N K;  3HOV C;  1YNJ A;  1R9T K;  4XLN A;  3M4O K;  3RZD C;  5C44 K;  5C3E C;  4C3I K;  4YFN A;  4A3F K;  1TWH K;  1TWG C;  1I6V A;  2NVQ C;  4A3K K;  5IYD C;  3GTP K;  2PMZ D;  3GTG K;  4C3H K;  4KMU A;  1TWF C;  3H0G C;  5FLM K;  3HOU K;  3HKZ L;  4QIW L;  4KN4 A;  1SFO C;  1R9T C;  3M4O C;  5C44 C;  2WAQ L;  4BBS K;  4C3I C;  4A3F C;  4A3J K;  4BY7 C;  4ZH4 A;  5M5W K;  2VUM C;  1TWH C;  4OIP A;  1TWC K;  1BDF A;  3S1Q C;  5IP9 C;  5M5X K;  4A3K C;  3GTP C;  4G7O A;  5C3E K;  3GTO K;  3HOW K;  3S1M K;  3GTK K;  2A69 A;  3GTL K;  4MEY A;  4C3H C;  2O5I A;  5FLM C;  3HOU C;  5D4D A;  3HKZ D;  3EQL A;  4LJZ A;  4QIW D;  4OIR A;  4GZY A;  1TWG K;  2NVY K;  4BBR K;  4C3J K;  2WAQ D;  4BBS C;  4YG2 A;  3GTQ C;  4A3G C;  2R93 C;  3S15 K;  4Y52 K;  1I6H K;  4A3E C;  4BXX C;  1TWC C;  1SFO K;  3GTO C;  3S1M C;  3HOW C;  4XLP A;  5IP7 K;  2A6E A;  4JK1 A;  3GTK C;  4LK1 A;  3GTL C;  1K83 K;  5IYC K;  4BY7 K;  5FJ8 K;  2VUM K;  1SMY A;  3S1Q K;  5IYD K;  4BBR C;  5IP9 K;  2NVY C;  3S15 C;  4C3J C;  4A3B C;  5M3M K; 
#chains in the Genus database with same CATH topology
 4GTC A;  3GTQ K;  4A3C C;  3HOY C;  4A3E K;  1O27 A;  1I3Q C;  2XCO A;  4QJV A;  1YCL A;  3GTP A;  4GTB A;  4A3M C;  3GTG A;  1PJ5 A;  3V4G A;  4A3B K;  5HL8 A;  3H3V D;  2JA8 K;  3S2H C;  4KM9 A;  3PO2 K;  1O2F B;  1TWA A;  2YU9 K;  3S2D C;  1AB4 A;  3I4N K;  1I50 C;  3K7A K;  2BE5 A;  1TWF A;  3SZZ A;  5C4J K;  3RZO C;  2R7Z C;  4LLG A;  2Y0S D;  3OPF A;  1R9T A;  1O24 A;  4IOA S;  4OIQ A;  4WFN S;  2PA8 L;  3JST A;  5IYB K;  3ERE D;  2WB1 D;  3S17 C;  3AH5 A;  5CJ9 A;  1L0W A;  4XSX A;  4MEX A;  1WCM C;  4O2D A;  3S16 C;  4C45 A;  3G4C A;  3PO3 C;  3I4M K;  2E2J C;  4MQ9 A;  3M3Y C;  3TFH A;  4KMD A;  2NVY A;  3AD9 C;  1I50 A;  1VH2 A;  2JA6 K;  1XXA A;  2JA5 K;  2GAH C;  4X6A C;  2GSU A;  2R7Z A;  1Y1V C;  1K83 A;  5DM6 S;  1GE9 A;  3GDZ A;  3GTM C;  1EQR A;  4A93 C;  1YNJ A;  4XLN A;  3RZD C;  5C3E C;  4C3I K;  2GSN A;  4PAA A;  1WQG A;  1TWH K;  3GTP K;  4DDQ A;  3GTG K;  2E2I A;  4C3H K;  4RMF A;  3A8K A;  1J6W A;  5IOT A;  2WAQ L;  4A3F C;  4IOC S;  4BXX K;  2VUM C;  5IP9 C;  3FKI A;  3GEE A;  1FEU A;  3GTK K;  2CFA A;  3TFI A;  3HOU C;  2E2H A;  3EQL A;  4LJZ A;  3S15 K;  4BBS C;  4YG2 A;  1XZQ B;  1Y1V A;  3G4A A;  2KWA A;  2Y3P A;  3S1M C;  3T00 A;  4XLP A;  2R92 A;  3AQP A;  5M3M K;  4C3J C;  2EBB A;  4NOI A;  4KN7 A;  1V5V A;  5M5Y K;  2KPU A;  4A3M K;  4AYB L;  1IS1 A;  4A3G K;  3S2H K;  1DCH A;  4QJV B;  1EI6 A;  1WOP A;  4LR2 A;  2NVX C;  3DXJ A;  4KB2 A;  3N3Y A;  4PAB A;  1O28 A;  3FOE A;  1I50 K;  1XXB A;  1Y1W C;  4OIN A;  4BY1 C;  2KQ1 A;  3GIR A;  1J6X A;  2NVT C;  4U67 S;  3CQZ C;  5CHP A;  2R7Z K;  3RZO K;  2PA8 D;  5JFE A;  1XZP A;  4IO9 S;  1IE0 A;  4J3N A;  2FQO A;  1F9N A;  1WCM K;  4GTE A;  1SFO A;  1PJ7 A;  4M1X A;  4A3D K;  2E2I K;  2B63 C;  1ISE A;  1PJ6 A;  4Y7N K;  3PO3 K;  1TWH A;  2E2J K;  2JA7 C;  3M3Y K;  4WJ3 M;  4Q4Z A;  1HI9 A;  3FKI K;  3OEP A;  2R93 A;  4G0U A;  1Y1W A;  1DCP A;  3HOX K;  2E2H K;  1ZBS A;  4XSZ A;  3LAP A;  2CW0 A;  4KMA A;  4X6A K;  3S1N C;  3GTK A;  4OIO A;  1Y1V K;  4KAW X;  3GTM K;  1DD5 A;  4A93 K;  2R92 K;  1VLO A;  3RZD K;  3S1R C;  4Q5S A;  4C2M K;  1XPP A;  4G7Z A;  1J6V A;  2PMZ L;  4A3J C;  3HOV C;  1I3Q A;  5L46 A;  2ZUF A;  4A3F K;  3Q3Q A;  1TWG C;  2NVQ C;  5IYD C;  3A8I A;  1KQ4 A;  3HOU K;  3HKZ L;  3SZY A;  2ZJQ S;  3M4O C;  1WOS A;  5C44 C;  4BBS K;  2FQT A;  4ZH4 A;  5M5W K;  3AD8 C;  1BDF A;  3S1Q C;  3S1M K;  4A3K C;  3CAG A;  2A69 A;  2O5I A;  4QIW D;  4OIR A;  3GEI A;  2XCR B;  4C3J K;  3GTQ C;  1VGX A;  1WOO A;  4A3E C;  1SFO K;  3GTO C;  3HOW C;  4JK1 A;  3GTL C;  4BY7 K;  2RH6 A;  4BLA A;  1SMY A;  1EK8 A;  1WCM A;  4A3B C;  2L5N A;  4GTA A;  3QX3 A;  4Y52 C;  1I6H C;  2JA8 C;  3ADA C;  1BS2 A;  1C0A A;  1Y1W K;  2R93 K;  3FHZ A;  5IP7 C;  4BY1 K;  2ZJP S;  3H3V L;  1WQH A;  5IOQ A;  5TJ3 A;  1WSV A;  1G51 A;  3HOZ C;  3IPJ A;  3K7A C;  3VA7 A;  4WIL A;  4YFK A;  5C4J C;  1B4A A;  2ZJR S;  3GTM A;  1XXC A;  4A3C K;  4A3L C;  2Y0S L;  3HOY K;  1XZP B;  3N0C A;  5C4X C;  2B63 K;  4P5A A;  3GTJ C;  3GTL A;  1I3Q K;  4GFQ A;  2WB1 L;  1IBA A;  1JOE A;  1X31 C;  1UV7 A;  2XCQ A;  3S14 C;  3I4M C;  4A3I C;  5TMF A;  2ZUE A;  5M3F K;  2V6U A;  3ORE A;  2VUM A;  3S2D K;  1YNN A;  5HQH A;  4WJ4 A;  2JA6 C;  1HQM A;  5JVH S;  2JA5 C;  2L3U A;  2A6H A;  5HL7 S;  3DLL S;  3S1R K;  1B4B A;  3WOD A;  3CF5 S;  4XCH A;  5E68 A;  1JVI A;  3BP8 C;  3N0B A;  1WIH A;  3GTJ A;  3HOV K;  3S17 K;  2PHC B;  4P5B A;  3GTG C;  3S16 K;  2NVQ K;  1ZYR A;  4G0W A;  3MML B;  2NVX A;  1TWA C;  3M4O K;  5C44 K;  4FZB A;  5IOS A;  2W7V A;  1I6V A;  1ZXO A;  1USM A;  4A3K K;  1BGW A;  4ILD A;  4KMU A;  1TWF C;  3H0G C;  3PIP S;  1EH1 A;  3CQZ A;  4KN4 A;  1O2A A;  1R9T C;  3BP3 A;  3L4J A;  5M5X K;  2D6F C;  3GTO K;  5C3E K;  3HOW K;  3GTL K;  4MEY A;  4KAT A;  5FLM C;  5JVO A;  5D4D A;  4GZY A;  2WAQ D;  4A3G C;  2B63 A;  1I6H K;  4Y52 K;  2GSO A;  5EGE A;  2V6T A;  1TWC C;  5JVG S;  3S0X A;  2V6S A;  4KC6 A;  2JA7 A;  5IP7 K;  3FOF A;  2A6E A;  4GTF A;  4LK1 A;  1YX2 A;  2ZFZ A;  2VUM K;  4BBR C;  5IP9 K;  2NVY C;  3GSI A;  3HOZ K;  2P8T A;  4KAR A;  2A68 A;  3H0G A;  5DM7 S;  5IYC C;  1K83 C;  1IW7 A;  1JQW A;  1DCO A;  2CFA B;  1IL2 A;  1O2B A;  4WFB S;  4A3L K;  3LPX A;  5C4X K;  1ZVU A;  3GTJ K;  1O25 A;  4AYB D;  4A3D C;  2P5M A;  2E2I C;  4Y7N C;  3S14 K;  1TWC A;  4A3I K;  1O26 A;  3AQO A;  3HXA A;  1INN A;  2NVX K;  4YFX A;  1TWG A;  3FKI C;  4KDD A;  3PO2 C;  3HOX C;  2E2H C;  2YU9 C;  4G7H A;  4AH6 A;  4WF9 S;  3BUE A;  3I4N C;  2NVT K;  3CQZ K;  1O29 A;  3A8J A;  1WOR A;  2R92 C;  4LK0 A;  2GAG C;  5TMC A;  2KXY A;  4C2M C;  3GTQ A;  1BJT A;  3TTG A;  3GTO A;  5IYB C;  1USO A;  4KB4 A;  2O5J A;  4KM8 A;  1WSR A;  1RU0 A;  2JA7 K;  1TWA K;  3T01 A;  2PPB A;  3L4K A;  4G0V A;  1ZQ1 C;  4BLB A;  2YU9 A;  1VJE A;  1TWF K;  3H0G K;  3S1N K;  4BKW A;  3LAJ A;  1R9T K;  3TFJ A;  4YFN A;  1F7U A;  4KAS A;  2JH3 A;  1F93 A;  1IQ0 A;  3PIO S;  2PMZ D;  1EFW A;  5FLM K;  1F7V A;  4QIW L;  1SFO C;  4C3I C;  1J98 A;  3GEH A;  4BY7 C;  4A3J K;  4GT9 A;  1TWC K;  1TWH C;  4OIP A;  3NUH A;  2RGR A;  3GTP C;  4G7O A;  3AD7 C;  4P9S A;  4LOW A;  4C3H C;  3HKZ D;  1TWG K;  4BBR K;  5FJ8 K;  5IYD K;  2NVY K;  4GTL A;  2R93 C;  3LYW A;  4GTD A;  4BXX C;  4WCE S;  1XZQ A;  4LQY A;  5IYC K;  3GTK C;  2JA6 A;  1K83 K;  5IOR A;  5EGH A;  1WQF A;  2JA5 A;  4WFA S;  3T02 A;  3S1Q K;  4KMH A;  4FM9 A;  3S15 C;  1VRQ C; 
#chains in the Genus database with same CATH homology
 4Y52 C;  1I6H C;  4NOI A;  2JA8 C;  4KN7 A;  5M5Y K;  4A3M K;  2A68 A;  4AYB L;  4A3G K;  1Y1W K;  2R93 K;  3GTQ K;  5IP7 C;  4A3C C;  5IYC C;  3HOY C;  4BY1 K;  3H3V L;  3S2H K;  1K83 C;  1IW7 A;  4A3E K;  4QJV B;  2NVX C;  3HOZ C;  1I3Q C;  3DXJ A;  4A3L K;  3K7A C;  4QJV A;  5C4X K;  4A3M C;  3GTJ K;  3HOZ K;  1I50 K;  4A3B K;  4YFK A;  5C4J C;  4AYB D;  1Y1W C;  4OIN A;  4BY1 C;  3H3V D;  2JA8 K;  3S2H C;  4A3D C;  2E2I C;  3PO2 K;  2NVT C;  3CQZ C;  4Y7N C;  3RZO K;  2R7Z K;  2YU9 K;  4A3L C;  3S2D C;  2Y0S L;  3HOY K;  3S14 K;  4A3C K;  4A3I K;  2PA8 D;  5C4X C;  3I4N K;  2B63 K;  3GTJ C;  1I50 C;  2NVX K;  1I3Q K;  3K7A K;  2BE5 A;  4YFX A;  3FKI C;  2WB1 L;  3PO2 C;  3HOX C;  2E2H C;  5C4J K;  3RZO C;  2R7Z C;  4LLG A;  2YU9 C;  2Y0S D;  4G7H A;  3I4M C;  3S14 C;  1WCM K;  4A3I C;  4A3D K;  3I4N C;  2E2I K;  2B63 C;  2NVT K;  5TMF A;  3CQZ K;  4Y7N K;  5M3F K;  3PO3 K;  4OIQ A;  3S2D K;  1YNN A;  5IYB K;  2PA8 L;  2JA7 C;  2E2J K;  3M3Y K;  2R92 C;  2WB1 D;  4Q4Z A;  3S17 C;  4LK0 A;  2JA6 C;  1HQM A;  4XSX A;  5TMC A;  2JA5 C;  4BXX K;  4MEX A;  1WCM C;  3FKI K;  2A6H A;  3S16 C;  4C2M C;  3HOX K;  3S1R K;  2E2H K;  3PO3 C;  4XSZ A;  3I4M K;  2CW0 A;  3WOD A;  4MQ9 A;  5IYB C;  2E2J C;  3M3Y C;  3S1N C;  4X6A K;  4OIO A;  1Y1V K;  2O5J A;  3GTM K;  2JA7 K;  4A93 K;  1TWA K;  2R92 K;  2PPB A;  3HOV K;  3S17 K;  2JA6 K;  3RZD K;  3S1R C;  2JA5 K;  4Q5S A;  3GTG C;  3S16 K;  4C2M K;  4X6A C;  1XPP A;  4G7Z A;  2NVQ K;  1Y1V C;  2PMZ L;  1ZYR A;  3GTM C;  4A3J C;  1TWF K;  3H0G K;  4A93 C;  1TWA C;  3S1N K;  3HOV C;  1YNJ A;  1R9T K;  4XLN A;  3M4O K;  3RZD C;  5C44 K;  5C3E C;  4C3I K;  4YFN A;  4A3F K;  1TWH K;  1TWG C;  1I6V A;  2NVQ C;  4A3K K;  5IYD C;  3GTP K;  2PMZ D;  3GTG K;  4C3H K;  4KMU A;  1TWF C;  3H0G C;  5FLM K;  3HOU K;  3HKZ L;  4QIW L;  4KN4 A;  1SFO C;  1R9T C;  3M4O C;  5C44 C;  2WAQ L;  4BBS K;  4C3I C;  4A3F C;  4A3J K;  4BY7 C;  4ZH4 A;  5M5W K;  2VUM C;  1TWH C;  4OIP A;  1TWC K;  1BDF A;  3S1Q C;  5IP9 C;  5M5X K;  4A3K C;  3GTP C;  4G7O A;  5C3E K;  3GTO K;  3HOW K;  3S1M K;  3GTK K;  2A69 A;  3GTL K;  4MEY A;  4C3H C;  2O5I A;  5FLM C;  3HOU C;  5D4D A;  3HKZ D;  3EQL A;  4LJZ A;  4QIW D;  4OIR A;  4GZY A;  1TWG K;  2NVY K;  4BBR K;  4C3J K;  2WAQ D;  4BBS C;  4YG2 A;  3GTQ C;  4A3G C;  2R93 C;  3S15 K;  4Y52 K;  1I6H K;  4A3E C;  4BXX C;  1TWC C;  1SFO K;  3GTO C;  3S1M C;  3HOW C;  4XLP A;  5IP7 K;  2A6E A;  4JK1 A;  3GTK C;  4LK1 A;  3GTL C;  1K83 K;  5IYC K;  4BY7 K;  5FJ8 K;  2VUM K;  1SMY A;  3S1Q K;  5IYD K;  4BBR C;  5IP9 K;  2NVY C;  3S15 C;  4C3J C;  4A3B C;  5M3M K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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