5IYBC

Human core-pic in the open state
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
275
structure length
275
Chain Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase II subunit RPB1
publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transcription, transferase/dna
total genus 58
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 5iybC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 5iybC01
3RZDC 2JA7C 2R92K 3S16K 3HOVC 2R92C 3S1NC 5M5XK 2NVTK 3CQZC 1Y1VK 1TWHK 2CW0A 1I6HK 3S2DK 2VUMC 4OIQA 3DXJA 5M5YK 4BY7K 5IYBK 4Y52K 4BXXC 2JA5C 4QJVA 3GTPC 2BE5A 1BDFA 4C3HC 1TWFK 2JA6K 1TWFC 2JA6C 3GTLC 4YFKA 3I4MC 3FKIK 1TWAC 3GTQK 5C44C 1I50K 2NVYK 3HKZD 2E2IC 3S15C 2E2IK 4XLPA 4A3LC 2O5JA 4A3EC 2JA8K 5C3EC 5IP7C 2PPBA 3GTOK 4KN7A 3HKZL 4C3IK 3M3YK 3HOUC 4A93K 3S2HC 1Y1WC 4OIOA 5IYDK 4A3GK 3GTKC 4C2MK 5C4JK 4A3IK 3M4OK 4MEYA 3S17C 2R93C 2WAQD 2A6EA 3S16C 5FLMK 2E2JK 2NVTC 5FLMC 4Q4ZA 4X6AK 1Y1VC 1TWHC 1I6HC 5C4XK 3S2DC 2PMZL 2WAQL 3GTJK 4BY7C 1K83K 2E2HC 3S1RK 5IYBC 4Y52C 3RZOC 4A3JK 2E2HK 3RZOK 5D4DA 5TMFA 4MQ9A 1SFOK 3WODA 4BBRK 1TWCK 3S14K 3S14C 3HOWK 4GZYA 4XLNA 3HOXK 2NVXK 5IYCK 3FKIC 3HOXC 4BBSK 3GTQC 5IP9K 1I50C 2NVYC 4C3JK 3EQLA 4A3KK 4A3KC 3H3VD 2JA8C 5M3MK 5M3FK 1YNNA 4LK1A 3GTOC 2Y0SD 4C3IC 3M3YC 4A93C 5FJ8K 3H3VL 3S1QK 5IYDC 3GTMK 3K7AK 4XSZA 4A3GC 4A3FK 4C2MC 5C4JC 4A3IC 3M4OC 1R9TK 4BY1K 2Y0SL 2PMZD 4A3CK 4JK1A 4A3CC 4G7HA 1SMYA 4A3BK 3HOZK 2E2JC 4X6AC 2WB1D 4LJZA 5C4XC 1I6VA 3S1RC 3GTJC 1K83C 1WCMK 4A3JC 4NOIA 2PA8L 2NVQK 3S1MK 3HOYK 2WB1L 3HOYC 4LK0A 2A69A 4KN4A 4AYBD 1SFOC 3GTGK 2YU9K 3H0GK 4BBRC 1TWCC 3HOWC 2A6HA 2B63K 1TWGK 2NVXC 4BBSC 4OIPA 5IYCC 4MEXA 5IP9C 4AYBL 4C3JC 4LLGA 4YG2A 4Y7NK 4YFNA 2R7ZK 3PO2K 2R7ZC 5M5WK 3I4NK 4YFXA 3I4NC 3RZDK 2JA7K 3HOVK 3S1QC 3S1NK 4G7ZA 4QIWL 1ZYRA 3CQZK 3GTMC 1I3QK 1I3QC 3K7AC 2VUMK 4A3FC 1R9TC 4BY1C 4XSXA 3PO3K 4BXXK 2JA5K 3PO3C 5TMCA 4G7OA 3GTPK 2PA8D 4A3BC 3HOZC 4C3HK 3GTLK 3I4MK 1WCMC 4OINA 1TWAK 1HQMA 2NVQC 3S1MC 5C44K 4A3MK 4A3MC 3S15K 4ZH4A 4A3DK 4A3DC 4A3LK 4A3EK 3GTGC 5C3EK 2YU9C 3H0GC 4KMUA 4Q5SA 1XPPA 4QJVB 2B63C 5IP7K 1YNJA 1TWGC 1IW7A 2A68A 4OIRA 3HOUK 3S2HK 1Y1WK 2O5IA 4Y7NC 3GTKK 4QIWD 3S17K 3PO2C 2R93K
chains in the Genus database with same CATH superfamily
5IOQA 1L0WA 2R92K 4WF9S 1Y1VK 1TWHK 3L4JA 3QX3A 1IS1A 3DXJA 4Y52K 4KAWX 4BXXC 2JA5C 4QJVA 1BDFA 1XZPB 4G0UA 2JA6K 1TWFC 1V5VA 1TWAC 2CFAA 2E2IK 3HKZD 4XLPA 4ILDA 4A3LC 3CAGA 4KN7A 3FOEA 4C3IK 3M3YK 4PABA 4A93K 4OIOA 4BKWA 2JA5A 5C4JK 2RH6A 3S17C 2A6EA 4KARA 2E2JK 1TWFA 5FLMC 1Y1VC 1TWHC 4GTEA 5C4XK 5DM7S 1TWAA 2WAQL 3GTJK 3RZOK 2E2HC 4A3JK 4Y52C 5IOSA 3S14K 1TWCK 4KASA 3HOWK 3N0CA 4XLNA 4BBSK 4KMAA 1JQWA 4A3KK 3H3VD 3G4CA 1J6WA 2W7VA 1IQ0A 4G0VA 3TFIA 1Y1VA 4C3IC 3M3YC 1TWHA 4A93C 1EFWA 3GTMK 2E2HA 5CHPA 1K83A 4XSZA 5C4JC 2PMZD 4LR2A 4A3CK 2E2JC 2Y3PA 5C4XC 3GTJC 1WCMK 3BP3A 4A3JC 1DCPA 4NOIA 2KWAA 2A69A 4AYBD 2YU9K 3PIPS 1TWCC 3HOWC 2A6HA 2B63K 1TWGK 4BBSC 1O28A 4KC6A 1B4BA 1VLOA 5M5WK 4YFXA 1EK8A 3HOVK 3LAPA 1WOSA 3GTJA 3CQZK 3GTMC 2VUMK 3A8IA 3PO3C 4WILA 4WFAS 3VA7A 1TWCA 5TJ3A 3T00A 1WCMC 1HQMA 5EGEA 2V6TA 1IE0A 3S15K 3FOFA 5C3EK 2YU9C 4QJVB 1PJ7A 2B63C 1YNJA 1TWGC 3HOUK 3S2HK 4WCES 3GTKK 4QIWD 1HI9A 1BS2A 4AH6A 3S16K 3HOVC 1O2FB 3CQZC 1WCMA 3S2DK 2VUMC 5IYBK 1AB4A 2BE5A 2B63A 1TWGA 1J6XA 1TWFK 1WSRA 3FKIK 3GIRA 4RMFA 1WQFA 5HQHA 3FHZA 3S15C 2JA8K 4KDDA 5C3EC 2FQTA 3G4AA 3CQZA 3A8KA 3HOUC 3S2HC 2VUMA 4GFQA 5IYDK 4A3GK 3GTKC 2WAQD 3GEHA 3S16C 5FLMK 3S2DC 1ZBSA 2ZFZA 2E2HK 1K83K 5IYBC 3SZYA 5D4DA 4IOCS 1SFOK 5JVGS 1PJ6A 3T01A 1O2BA 2NVXK 5IYCK 3FKIC 3HOXC 3GTKA 3EQLA 3T02A 3A8JA 2JA8C 5M3FK 1YNNA 3TFHA 3S1QK 5IYDC 4A3GC 1R9TK 4PAAA 2KXYA 4JK1A 4A3BK 3V4GA 3LAJA 2V6SA 3FKIA 4G0WA 1K83C 4KM9A 2PA8L 2PHCB 3HOYC 2WB1L 1SFOC 4KMDA 2NVXC 5IYCC 3NUHA 4Y7NK 4YFNA 1KQ4A 2R7ZC 3RZDK 3S1QC 1F93A 4G7ZA 4XCHA 1I3QC 5IORA 1O27A 1ZVUA 1R9TC 4XSXA 3PO3K 1SFOA 4A3BC 2XCQA 2NVXA 2ZJRS 3GTLK 1EH1A 4C45A 1XXAA 4A3MC 4ZH4A 4A3DC 2R7ZA 1XPPA 3DLLS 4OIRA 1I3QA 3OREA 5HL8A 1YX2A 4Y7NC 1R9TA 3MMLB 1XZPA 2R93K 3AQPA 3RZDC 2D6FC 2ZJPS 1X31C 2ZUEA 4WFBS 2CW0A 4M1XA 1I6HK 2P5MA 4OIQA 5M5YK 2V6UA 1EQRA 4KATA 4GTDA 1J98A 4GTFA 4IO9S 3GTLC 4YFKA 4KB4A 1Y1WA 3GTQK 1C0AA 3GEIA 2NVYK 2O5JA 3GEEA 1IL2A 2EBBA 3AD9C 1XZQA 3GDZA 1PJ5A 4C2MK 2CFAB 4MEYA 1O24A 4P9SA 2R93C 4J3NA 1RU0A 4KMHA 4Q4ZA 3GTLA 3AD7C 1I6HC 2PMZL 4WJ4A 5TMFA 3WODA 1UV7A 4BBRK 3GTOA 3HOXK 3GTQC 5IP9K 2NVYC 4C3JK 1DCHA 3OPFA 5M3MK 2R93A 4LQYA 2GAHC 2KQ1A 2KPUA 1VH2A 3HXAA 4C2MC 1ISEA 3AQOA 3CF5S 4GTCA 2Y0SL 4GT9A 1WIHA 4G7HA 4LOWA 3GSIA 1IBAA 2ZUFA 2WB1D 4LJZA 5CJ9A 1I6VA 3GTQA 2NVYA 2L3UA 3S1MK 3HOYK 4KN4A 3S0XA 3GTGK 1VRQC 4BBRC 3H0GK 1DCOA 1WQGA 3PIOS 5IP9C 4C3JC 4YG2A 5JVOA 2R7ZK 3PO2K 1WQHA 3I4NC 2JA7K 2GSUA 3S1NK 2GAGC 4QIWL 1I3QK 4O2DA 3TFJA 1EI6A 3ERED 4G7OA 1JVIA 3GTPK 4KM8A 1BGWA 1VGXA 4C3HK 1O29A 1O26A 3N3YA 2JH3A 4DDQA 3I4MK 4OINA 3S1MC 5C44K 4A3MK 4A3DK 4A3EK 3GTGC 5IP7K 3H0GC 3N0BA 1IW7A 2ZJQS 2A68A 1USOA 3LYWA 1Y1WK 3PO2C 2L5NA 2JA7C 1ZQ1C 2R92C 3S1NC 5M5XK 2NVTK 1JOEA 3SZZA 4BY7K 1XZQB 3GTGA 3GTPC 3H0GA 4C3HC 3IPJA 2JA6C 1WOOA 3I4MC 3AD8C 5C44C 1I50K 2E2IC 4P5AA 4U67S 4A3EC 5IP7C 3BUEA 2JA7A 2PPBA 4BLBA 3GTOK 5DM6S 3HKZL 3AH5A 2R92A 2P8TA 1F7VA 1Y1WC 2GSNA 4A3IK 3M4OK 3GTPA 2NVTC 4P5BA 2JA6A 4X6AK 2XCRB 3Q3QA 3S1RK 3BP8C 4BY7C 3LPXA 3RZOC 2E2IA 2XCOA 4WJ3M 4MQ9A 4GTBA 2GSOA 4WFNS 3S14C 1O25A 2RGRA 4GZYA 1BJTA 4GTAA 1I50C 1WOPA 5EGHA 1F7UA 4A3KC 4LK1A 3JSTA 3GTOC 3L4KA 2Y0SD 1WORA 5FJ8K 3H3VL 3K7AK 5HL7S 4A3FK 4A3IC 3M4OC 4BY1K 1XXCA 4KB2A 4A3CC 4GTLA 1SMYA 3HOZK 4X6AC 3S1RC 5L46A 1I50A 2NVQK 3ADAC 1F9NA 1ZXOA 1VJEA 4LK0A 1DD5A 5E68A 4OIPA 4MEXA 3GTMA 1WSVA 4AYBL 1FEUA 4LLGA 1J6VA 3I4NK 1B4AA 1GE9A 1ZYRA 1INNA 3K7AC 1YCLA 4A3FC 4BY1C 4BXXK 2JA5K 5TMCA 2PA8D 1USMA 3HOZC 5JVHS 2YU9A 4FZBA 4IOAS 4FM9A 1G51A 1TWAK 2NVQC 5JFEA 1O2AA 3TTGA 4A3LK 3OEPA 4KMUA 4Q5SA 5IOTA 2FQOA 2O5IA 4BLAA 1XXBA 3S17K
chains in the Genus database with same CATH topology
3RZDC 2JA7C 2R92K 3S16K 3HOVC 2R92C 3S1NC 5M5XK 2NVTK 3CQZC 1Y1VK 1TWHK 2CW0A 1I6HK 3S2DK 2VUMC 4OIQA 3DXJA 5M5YK 4BY7K 5IYBK 4Y52K 4BXXC 2JA5C 4QJVA 3GTPC 2BE5A 1BDFA 4C3HC 1TWFK 2JA6K 1TWFC 2JA6C 3GTLC 4YFKA 3I4MC 3FKIK 1TWAC 3GTQK 5C44C 1I50K 2NVYK 3HKZD 2E2IC 3S15C 2E2IK 4XLPA 4A3LC 2O5JA 4A3EC 2JA8K 5C3EC 5IP7C 2PPBA 3GTOK 4KN7A 3HKZL 4C3IK 3M3YK 3HOUC 4A93K 3S2HC 1Y1WC 4OIOA 5IYDK 4A3GK 3GTKC 4C2MK 5C4JK 4A3IK 3M4OK 4MEYA 3S17C 2R93C 2WAQD 2A6EA 3S16C 5FLMK 2E2JK 2NVTC 5FLMC 4Q4ZA 4X6AK 1Y1VC 1TWHC 1I6HC 5C4XK 3S2DC 2PMZL 2WAQL 3GTJK 4BY7C 1K83K 2E2HC 3S1RK 5IYBC 4Y52C 3RZOC 4A3JK 2E2HK 3RZOK 5D4DA 5TMFA 4MQ9A 1SFOK 3WODA 4BBRK 1TWCK 3S14K 3S14C 3HOWK 4GZYA 4XLNA 3HOXK 2NVXK 5IYCK 3FKIC 3HOXC 4BBSK 3GTQC 5IP9K 1I50C 2NVYC 4C3JK 3EQLA 4A3KK 4A3KC 3H3VD 2JA8C 5M3MK 5M3FK 1YNNA 4LK1A 3GTOC 2Y0SD 4C3IC 3M3YC 4A93C 5FJ8K 3H3VL 3S1QK 5IYDC 3GTMK 3K7AK 4XSZA 4A3GC 4A3FK 4C2MC 5C4JC 4A3IC 3M4OC 1R9TK 4BY1K 2Y0SL 2PMZD 4A3CK 4JK1A 4A3CC 4G7HA 1SMYA 4A3BK 3HOZK 2E2JC 4X6AC 2WB1D 4LJZA 5C4XC 1I6VA 3S1RC 3GTJC 1K83C 1WCMK 4A3JC 4NOIA 2PA8L 2NVQK 3S1MK 3HOYK 2WB1L 3HOYC 4LK0A 2A69A 4KN4A 4AYBD 1SFOC 3GTGK 2YU9K 3H0GK 4BBRC 1TWCC 3HOWC 2A6HA 2B63K 1TWGK 2NVXC 4BBSC 4OIPA 5IYCC 4MEXA 5IP9C 4AYBL 4C3JC 4LLGA 4YG2A 4Y7NK 4YFNA 2R7ZK 3PO2K 2R7ZC 5M5WK 3I4NK 4YFXA 3I4NC 3RZDK 2JA7K 3HOVK 3S1QC 3S1NK 4G7ZA 4QIWL 1ZYRA 3CQZK 3GTMC 1I3QK 1I3QC 3K7AC 2VUMK 4A3FC 1R9TC 4BY1C 4XSXA 3PO3K 4BXXK 2JA5K 3PO3C 5TMCA 4G7OA 3GTPK 2PA8D 4A3BC 3HOZC 4C3HK 3GTLK 3I4MK 1WCMC 4OINA 1TWAK 1HQMA 2NVQC 3S1MC 5C44K 4A3MK 4A3MC 3S15K 4ZH4A 4A3DK 4A3DC 4A3LK 4A3EK 3GTGC 5C3EK 2YU9C 3H0GC 4KMUA 4Q5SA 1XPPA 4QJVB 2B63C 5IP7K 1YNJA 1TWGC 1IW7A 2A68A 4OIRA 3HOUK 3S2HK 1Y1WK 2O5IA 4Y7NC 3GTKK 4QIWD 3S17K 3PO2C 2R93K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RZD C;  2JA7 C;  2R92 K;  3S16 K;  3HOV C;  2R92 C;  3S1N C;  5M5X K;  2NVT K;  3CQZ C;  1Y1V K;  1TWH K;  2CW0 A;  1I6H K;  3S2D K;  2VUM C;  4OIQ A;  3DXJ A;  5M5Y K;  4BY7 K;  5IYB K;  4Y52 K;  4BXX C;  2JA5 C;  4QJV A;  3GTP C;  2BE5 A;  1BDF A;  4C3H C;  1TWF K;  2JA6 K;  1TWF C;  2JA6 C;  3GTL C;  4YFK A;  3I4M C;  3FKI K;  1TWA C;  3GTQ K;  5C44 C;  1I50 K;  2NVY K;  3HKZ D;  2E2I C;  3S15 C;  2E2I K;  4XLP A;  4A3L C;  2O5J A;  4A3E C;  2JA8 K;  5C3E C;  5IP7 C;  2PPB A;  3GTO K;  4KN7 A;  3HKZ L;  4C3I K;  3M3Y K;  3HOU C;  4A93 K;  3S2H C;  1Y1W C;  4OIO A;  5IYD K;  4A3G K;  3GTK C;  4C2M K;  5C4J K;  4A3I K;  3M4O K;  4MEY A;  3S17 C;  2R93 C;  2WAQ D;  2A6E A;  3S16 C;  5FLM K;  2E2J K;  2NVT C;  5FLM C;  4Q4Z A;  4X6A K;  1Y1V C;  1TWH C;  1I6H C;  5C4X K;  3S2D C;  2PMZ L;  2WAQ L;  3GTJ K;  4BY7 C;  1K83 K;  2E2H C;  3S1R K;  5IYB C;  4Y52 C;  3RZO C;  4A3J K;  2E2H K;  3RZO K;  5D4D A;  5TMF A;  4MQ9 A;  1SFO K;  3WOD A;  4BBR K;  1TWC K;  3S14 K;  3S14 C;  3HOW K;  4GZY A;  4XLN A;  3HOX K;  2NVX K;  5IYC K;  3FKI C;  3HOX C;  4BBS K;  3GTQ C;  5IP9 K;  1I50 C;  2NVY C;  4C3J K;  3EQL A;  4A3K K;  4A3K C;  3H3V D;  2JA8 C;  5M3M K;  5M3F K;  1YNN A;  4LK1 A;  3GTO C;  2Y0S D;  4C3I C;  3M3Y C;  4A93 C;  5FJ8 K;  3H3V L;  3S1Q K;  5IYD C;  3GTM K;  3K7A K;  4XSZ A;  4A3G C;  4A3F K;  4C2M C;  5C4J C;  4A3I C;  3M4O C;  1R9T K;  4BY1 K;  2Y0S L;  2PMZ D;  4A3C K;  4JK1 A;  4A3C C;  4G7H A;  1SMY A;  4A3B K;  3HOZ K;  2E2J C;  4X6A C;  2WB1 D;  4LJZ A;  5C4X C;  1I6V A;  3S1R C;  3GTJ C;  1K83 C;  1WCM K;  4A3J C;  4NOI A;  2PA8 L;  2NVQ K;  3S1M K;  3HOY K;  2WB1 L;  3HOY C;  4LK0 A;  2A69 A;  4KN4 A;  4AYB D;  1SFO C;  3GTG K;  2YU9 K;  3H0G K;  4BBR C;  1TWC C;  3HOW C;  2A6H A;  2B63 K;  1TWG K;  2NVX C;  4BBS C;  4OIP A;  5IYC C;  4MEX A;  5IP9 C;  4AYB L;  4C3J C;  4LLG A;  4YG2 A;  4Y7N K;  4YFN A;  2R7Z K;  3PO2 K;  2R7Z C;  5M5W K;  3I4N K;  4YFX A;  3I4N C;  3RZD K;  2JA7 K;  3HOV K;  3S1Q C;  3S1N K;  4G7Z A;  4QIW L;  1ZYR A;  3CQZ K;  3GTM C;  1I3Q K;  1I3Q C;  3K7A C;  2VUM K;  4A3F C;  1R9T C;  4BY1 C;  4XSX A;  3PO3 K;  4BXX K;  2JA5 K;  3PO3 C;  5TMC A;  4G7O A;  3GTP K;  2PA8 D;  4A3B C;  3HOZ C;  4C3H K;  3GTL K;  3I4M K;  1WCM C;  4OIN A;  1TWA K;  1HQM A;  2NVQ C;  3S1M C;  5C44 K;  4A3M K;  4A3M C;  3S15 K;  4ZH4 A;  4A3D K;  4A3D C;  4A3L K;  4A3E K;  3GTG C;  5C3E K;  2YU9 C;  3H0G C;  4KMU A;  4Q5S A;  1XPP A;  4QJV B;  2B63 C;  5IP7 K;  1YNJ A;  1TWG C;  1IW7 A;  2A68 A;  4OIR A;  3HOU K;  3S2H K;  1Y1W K;  2O5I A;  4Y7N C;  3GTK K;  4QIW D;  3S17 K;  3PO2 C;  2R93 K; 
#chains in the Genus database with same CATH topology
 5IOQ A;  1L0W A;  2R92 K;  4WF9 S;  1Y1V K;  1TWH K;  3L4J A;  3QX3 A;  1IS1 A;  3DXJ A;  4Y52 K;  4KAW X;  4BXX C;  2JA5 C;  4QJV A;  1BDF A;  1XZP B;  4G0U A;  2JA6 K;  1TWF C;  1V5V A;  1TWA C;  2CFA A;  2E2I K;  3HKZ D;  4XLP A;  4ILD A;  4A3L C;  3CAG A;  4KN7 A;  3FOE A;  4C3I K;  3M3Y K;  4PAB A;  4A93 K;  4OIO A;  4BKW A;  2JA5 A;  5C4J K;  2RH6 A;  3S17 C;  2A6E A;  4KAR A;  2E2J K;  1TWF A;  5FLM C;  1Y1V C;  1TWH C;  4GTE A;  5C4X K;  5DM7 S;  1TWA A;  2WAQ L;  3GTJ K;  3RZO K;  2E2H C;  4A3J K;  4Y52 C;  5IOS A;  3S14 K;  1TWC K;  4KAS A;  3HOW K;  3N0C A;  4XLN A;  4BBS K;  4KMA A;  1JQW A;  4A3K K;  3H3V D;  3G4C A;  1J6W A;  2W7V A;  1IQ0 A;  4G0V A;  3TFI A;  1Y1V A;  4C3I C;  3M3Y C;  1TWH A;  4A93 C;  1EFW A;  3GTM K;  2E2H A;  5CHP A;  1K83 A;  4XSZ A;  5C4J C;  2PMZ D;  4LR2 A;  4A3C K;  2E2J C;  2Y3P A;  5C4X C;  3GTJ C;  1WCM K;  3BP3 A;  4A3J C;  1DCP A;  4NOI A;  2KWA A;  2A69 A;  4AYB D;  2YU9 K;  3PIP S;  1TWC C;  3HOW C;  2A6H A;  2B63 K;  1TWG K;  4BBS C;  1O28 A;  4KC6 A;  1B4B A;  1VLO A;  5M5W K;  4YFX A;  1EK8 A;  3HOV K;  3LAP A;  1WOS A;  3GTJ A;  3CQZ K;  3GTM C;  2VUM K;  3A8I A;  3PO3 C;  4WIL A;  4WFA S;  3VA7 A;  1TWC A;  5TJ3 A;  3T00 A;  1WCM C;  1HQM A;  5EGE A;  2V6T A;  1IE0 A;  3S15 K;  3FOF A;  5C3E K;  2YU9 C;  4QJV B;  1PJ7 A;  2B63 C;  1YNJ A;  1TWG C;  3HOU K;  3S2H K;  4WCE S;  3GTK K;  4QIW D;  1HI9 A;  1BS2 A;  4AH6 A;  3S16 K;  3HOV C;  1O2F B;  3CQZ C;  1WCM A;  3S2D K;  2VUM C;  5IYB K;  1AB4 A;  2BE5 A;  2B63 A;  1TWG A;  1J6X A;  1TWF K;  1WSR A;  3FKI K;  3GIR A;  4RMF A;  1WQF A;  5HQH A;  3FHZ A;  3S15 C;  2JA8 K;  4KDD A;  5C3E C;  2FQT A;  3G4A A;  3CQZ A;  3A8K A;  3HOU C;  3S2H C;  2VUM A;  4GFQ A;  5IYD K;  4A3G K;  3GTK C;  2WAQ D;  3GEH A;  3S16 C;  5FLM K;  3S2D C;  1ZBS A;  2ZFZ A;  2E2H K;  1K83 K;  5IYB C;  3SZY A;  5D4D A;  4IOC S;  1SFO K;  5JVG S;  1PJ6 A;  3T01 A;  1O2B A;  2NVX K;  5IYC K;  3FKI C;  3HOX C;  3GTK A;  3EQL A;  3T02 A;  3A8J A;  2JA8 C;  5M3F K;  1YNN A;  3TFH A;  3S1Q K;  5IYD C;  4A3G C;  1R9T K;  4PAA A;  2KXY A;  4JK1 A;  4A3B K;  3V4G A;  3LAJ A;  2V6S A;  3FKI A;  4G0W A;  1K83 C;  4KM9 A;  2PA8 L;  2PHC B;  3HOY C;  2WB1 L;  1SFO C;  4KMD A;  2NVX C;  5IYC C;  3NUH A;  4Y7N K;  4YFN A;  1KQ4 A;  2R7Z C;  3RZD K;  3S1Q C;  1F93 A;  4G7Z A;  4XCH A;  1I3Q C;  5IOR A;  1O27 A;  1ZVU A;  1R9T C;  4XSX A;  3PO3 K;  1SFO A;  4A3B C;  2XCQ A;  2NVX A;  2ZJR S;  3GTL K;  1EH1 A;  4C45 A;  1XXA A;  4A3M C;  4ZH4 A;  4A3D C;  2R7Z A;  1XPP A;  3DLL S;  4OIR A;  1I3Q A;  3ORE A;  5HL8 A;  1YX2 A;  4Y7N C;  1R9T A;  3MML B;  1XZP A;  2R93 K;  3AQP A;  3RZD C;  2D6F C;  2ZJP S;  1X31 C;  2ZUE A;  4WFB S;  2CW0 A;  4M1X A;  1I6H K;  2P5M A;  4OIQ A;  5M5Y K;  2V6U A;  1EQR A;  4KAT A;  4GTD A;  1J98 A;  4GTF A;  4IO9 S;  3GTL C;  4YFK A;  4KB4 A;  1Y1W A;  3GTQ K;  1C0A A;  3GEI A;  2NVY K;  2O5J A;  3GEE A;  1IL2 A;  2EBB A;  3AD9 C;  1XZQ A;  3GDZ A;  1PJ5 A;  4C2M K;  2CFA B;  4MEY A;  1O24 A;  4P9S A;  2R93 C;  4J3N A;  1RU0 A;  4KMH A;  4Q4Z A;  3GTL A;  3AD7 C;  1I6H C;  2PMZ L;  4WJ4 A;  5TMF A;  3WOD A;  1UV7 A;  4BBR K;  3GTO A;  3HOX K;  3GTQ C;  5IP9 K;  2NVY C;  4C3J K;  1DCH A;  3OPF A;  5M3M K;  2R93 A;  4LQY A;  2GAH C;  2KQ1 A;  2KPU A;  1VH2 A;  3HXA A;  4C2M C;  1ISE A;  3AQO A;  3CF5 S;  4GTC A;  2Y0S L;  4GT9 A;  1WIH A;  4G7H A;  4LOW A;  3GSI A;  1IBA A;  2ZUF A;  2WB1 D;  4LJZ A;  5CJ9 A;  1I6V A;  3GTQ A;  2NVY A;  2L3U A;  3S1M K;  3HOY K;  4KN4 A;  3S0X A;  3GTG K;  1VRQ C;  4BBR C;  3H0G K;  1DCO A;  1WQG A;  3PIO S;  5IP9 C;  4C3J C;  4YG2 A;  5JVO A;  2R7Z K;  3PO2 K;  1WQH A;  3I4N C;  2JA7 K;  2GSU A;  3S1N K;  2GAG C;  4QIW L;  1I3Q K;  4O2D A;  3TFJ A;  1EI6 A;  3ERE D;  4G7O A;  1JVI A;  3GTP K;  4KM8 A;  1BGW A;  1VGX A;  4C3H K;  1O29 A;  1O26 A;  3N3Y A;  2JH3 A;  4DDQ A;  3I4M K;  4OIN A;  3S1M C;  5C44 K;  4A3M K;  4A3D K;  4A3E K;  3GTG C;  5IP7 K;  3H0G C;  3N0B A;  1IW7 A;  2ZJQ S;  2A68 A;  1USO A;  3LYW A;  1Y1W K;  3PO2 C;  2L5N A;  2JA7 C;  1ZQ1 C;  2R92 C;  3S1N C;  5M5X K;  2NVT K;  1JOE A;  3SZZ A;  4BY7 K;  1XZQ B;  3GTG A;  3GTP C;  3H0G A;  4C3H C;  3IPJ A;  2JA6 C;  1WOO A;  3I4M C;  3AD8 C;  5C44 C;  1I50 K;  2E2I C;  4P5A A;  4U67 S;  4A3E C;  5IP7 C;  3BUE A;  2JA7 A;  2PPB A;  4BLB A;  3GTO K;  5DM6 S;  3HKZ L;  3AH5 A;  2R92 A;  2P8T A;  1F7V A;  1Y1W C;  2GSN A;  4A3I K;  3M4O K;  3GTP A;  2NVT C;  4P5B A;  2JA6 A;  4X6A K;  2XCR B;  3Q3Q A;  3S1R K;  3BP8 C;  4BY7 C;  3LPX A;  3RZO C;  2E2I A;  2XCO A;  4WJ3 M;  4MQ9 A;  4GTB A;  2GSO A;  4WFN S;  3S14 C;  1O25 A;  2RGR A;  4GZY A;  1BJT A;  4GTA A;  1I50 C;  1WOP A;  5EGH A;  1F7U A;  4A3K C;  4LK1 A;  3JST A;  3GTO C;  3L4K A;  2Y0S D;  1WOR A;  5FJ8 K;  3H3V L;  3K7A K;  5HL7 S;  4A3F K;  4A3I C;  3M4O C;  4BY1 K;  1XXC A;  4KB2 A;  4A3C C;  4GTL A;  1SMY A;  3HOZ K;  4X6A C;  3S1R C;  5L46 A;  1I50 A;  2NVQ K;  3ADA C;  1F9N A;  1ZXO A;  1VJE A;  4LK0 A;  1DD5 A;  5E68 A;  4OIP A;  4MEX A;  3GTM A;  1WSV A;  4AYB L;  1FEU A;  4LLG A;  1J6V A;  3I4N K;  1B4A A;  1GE9 A;  1ZYR A;  1INN A;  3K7A C;  1YCL A;  4A3F C;  4BY1 C;  4BXX K;  2JA5 K;  5TMC A;  2PA8 D;  1USM A;  3HOZ C;  5JVH S;  2YU9 A;  4FZB A;  4IOA S;  4FM9 A;  1G51 A;  1TWA K;  2NVQ C;  5JFE A;  1O2A A;  3TTG A;  4A3L K;  3OEP A;  4KMU A;  4Q5S A;  5IOT A;  2FQO A;  2O5I A;  4BLA A;  1XXB A;  3S17 K; 
#chains in the Genus database with same CATH homology
 3RZD C;  2JA7 C;  2R92 K;  3S16 K;  3HOV C;  2R92 C;  3S1N C;  5M5X K;  2NVT K;  3CQZ C;  1Y1V K;  1TWH K;  2CW0 A;  1I6H K;  3S2D K;  2VUM C;  4OIQ A;  3DXJ A;  5M5Y K;  4BY7 K;  5IYB K;  4Y52 K;  4BXX C;  2JA5 C;  4QJV A;  3GTP C;  2BE5 A;  1BDF A;  4C3H C;  1TWF K;  2JA6 K;  1TWF C;  2JA6 C;  3GTL C;  4YFK A;  3I4M C;  3FKI K;  1TWA C;  3GTQ K;  5C44 C;  1I50 K;  2NVY K;  3HKZ D;  2E2I C;  3S15 C;  2E2I K;  4XLP A;  4A3L C;  2O5J A;  4A3E C;  2JA8 K;  5C3E C;  5IP7 C;  2PPB A;  3GTO K;  4KN7 A;  3HKZ L;  4C3I K;  3M3Y K;  3HOU C;  4A93 K;  3S2H C;  1Y1W C;  4OIO A;  5IYD K;  4A3G K;  3GTK C;  4C2M K;  5C4J K;  4A3I K;  3M4O K;  4MEY A;  3S17 C;  2R93 C;  2WAQ D;  2A6E A;  3S16 C;  5FLM K;  2E2J K;  2NVT C;  5FLM C;  4Q4Z A;  4X6A K;  1Y1V C;  1TWH C;  1I6H C;  5C4X K;  3S2D C;  2PMZ L;  2WAQ L;  3GTJ K;  4BY7 C;  1K83 K;  2E2H C;  3S1R K;  5IYB C;  4Y52 C;  3RZO C;  4A3J K;  2E2H K;  3RZO K;  5D4D A;  5TMF A;  4MQ9 A;  1SFO K;  3WOD A;  4BBR K;  1TWC K;  3S14 K;  3S14 C;  3HOW K;  4GZY A;  4XLN A;  3HOX K;  2NVX K;  5IYC K;  3FKI C;  3HOX C;  4BBS K;  3GTQ C;  5IP9 K;  1I50 C;  2NVY C;  4C3J K;  3EQL A;  4A3K K;  4A3K C;  3H3V D;  2JA8 C;  5M3M K;  5M3F K;  1YNN A;  4LK1 A;  3GTO C;  2Y0S D;  4C3I C;  3M3Y C;  4A93 C;  5FJ8 K;  3H3V L;  3S1Q K;  5IYD C;  3GTM K;  3K7A K;  4XSZ A;  4A3G C;  4A3F K;  4C2M C;  5C4J C;  4A3I C;  3M4O C;  1R9T K;  4BY1 K;  2Y0S L;  2PMZ D;  4A3C K;  4JK1 A;  4A3C C;  4G7H A;  1SMY A;  4A3B K;  3HOZ K;  2E2J C;  4X6A C;  2WB1 D;  4LJZ A;  5C4X C;  1I6V A;  3S1R C;  3GTJ C;  1K83 C;  1WCM K;  4A3J C;  4NOI A;  2PA8 L;  2NVQ K;  3S1M K;  3HOY K;  2WB1 L;  3HOY C;  4LK0 A;  2A69 A;  4KN4 A;  4AYB D;  1SFO C;  3GTG K;  2YU9 K;  3H0G K;  4BBR C;  1TWC C;  3HOW C;  2A6H A;  2B63 K;  1TWG K;  2NVX C;  4BBS C;  4OIP A;  5IYC C;  4MEX A;  5IP9 C;  4AYB L;  4C3J C;  4LLG A;  4YG2 A;  4Y7N K;  4YFN A;  2R7Z K;  3PO2 K;  2R7Z C;  5M5W K;  3I4N K;  4YFX A;  3I4N C;  3RZD K;  2JA7 K;  3HOV K;  3S1Q C;  3S1N K;  4G7Z A;  4QIW L;  1ZYR A;  3CQZ K;  3GTM C;  1I3Q K;  1I3Q C;  3K7A C;  2VUM K;  4A3F C;  1R9T C;  4BY1 C;  4XSX A;  3PO3 K;  4BXX K;  2JA5 K;  3PO3 C;  5TMC A;  4G7O A;  3GTP K;  2PA8 D;  4A3B C;  3HOZ C;  4C3H K;  3GTL K;  3I4M K;  1WCM C;  4OIN A;  1TWA K;  1HQM A;  2NVQ C;  3S1M C;  5C44 K;  4A3M K;  4A3M C;  3S15 K;  4ZH4 A;  4A3D K;  4A3D C;  4A3L K;  4A3E K;  3GTG C;  5C3E K;  2YU9 C;  3H0G C;  4KMU A;  4Q5S A;  1XPP A;  4QJV B;  2B63 C;  5IP7 K;  1YNJ A;  1TWG C;  1IW7 A;  2A68 A;  4OIR A;  3HOU K;  3S2H K;  1Y1W K;  2O5I A;  4Y7N C;  3GTK K;  4QIW D;  3S17 K;  3PO2 C;  2R93 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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