5IYCL

Human core-pic in the initial transcribing state
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
QPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5iycL00
2JA5L 4A3DL 3GTJL 3GTML 2NVTL 3GTKL 4BXXL 4C3IL 2WB1P 2YU9L 1Y1WL 2E2HL 1I50L 4QIWP 3RZOL 5FLML 2VUML 1SFOL 3HOUL 3RZDL 5IYCL 1I6HL 3GTPL 3S17L 3H3VM 1WCML 1TWHL 5M5YL 3GTQL 2E2JL 5C4JL 3HOXL 2B63L 4C2M1 3GTLL 3CQZL 3FKIL 3H0GL 2NVQL 5C3EL 4A3EL 5C4XL 2Y0SP 4C3JL 3S1QL 1TWCL 5M3ML 1TWFL 2R93L 2NVXL 5M5XL 2JA6L 3M3YL 3I4NL 2E2IL 2PMZP 1TWGL 4A3BL 1R9TL 4Y52L 3HOZL 3GTOL 3HOYL 2WAQP 3S1RL 3HKZP 4A3FL 4C3HL 4A3ML 5C44L 4BBSL 3S1ML 3I4ML 4A3IL 4A93L 4BY1L 3S14L 1Y1VL 3GTGL 3HOVL 5IYDL 3S2HL 4A3GL 5IYBL 4X6AL 4BBRL 5IP9L 2JA8L 1I3QL 4A3KL 2R7ZL 4Y7NL 3K7AL 3PO3L 1TWAL 1K83L 2NVYL 4A3CL 4AYBP 3S15L 3S1NL 3S16L 4BY7L 3S2DL 5IP7L 3M4OL 5M3FL 3PO2L 2R92L 4A3JL 2JA7L 5FJ8L 4A3LL 3HOWL 5M5WL
chains in the Genus database with same CATH superfamily
4E6YA 4AHYA 3GTJL 1BQ8A 2WB1P 2JI3A 1IU6A 2E2HL 3LWQB 2PYAA 1B13A 1H7VA 2M6OA 5FLML 1SFOL 2JI1A 1T9OA 3RZDL 4WFN1 4YWMA 1I6HL 3S17L 4LHLA 2E2JL 1LKMA 4JAGA 1ZRPA 2B63L 1RDVA 3GTLL 4POFA 3LWOB 5C3EL 5C4XL 1TWCL 5JVH1 3HAXC 2R93L 2NVXL 3KYXA 2A6ED 1SMUA 1B71A 5GAHc 2E2IL 2PMZP 1YK5A 1PFYA 2C6AA 4AI0A 2M4VA 3RYGA 4JADA 1BRFA 1RYTA 2MS3A 1S24A 2C6BA 3HKZP 2M4YA 1DVBA 4A3ML 3S1ML 3P8BA 1FHHA 3SS2A 4BY1L 1LTLA 2CKCA 3WWLA 4BBRL 5AI2A 2JA8L 2R7ZL 3PO3L 3P2AA 1R0FA 3PZAA 2Z3QB 1VZHA 3S15L 1PZXA 2B5ID 2ERSA 2ERJA 2M6PA 3MQKB 4A3JL 5FJ8L 3WWNB 1R0HA 5M5WL 2JA5L 3KYUA 2VL6A 3GTML 3J7Z1 4XGHA 2YU9L 1I50L 3H9CA 2VUML 5EINC 5DM61 5C4JL 1QYBA 4AHZA 3CQZL 3H0GL 5RXNA 1YK4A 2Y0SP 3S1QL 4RXNA 5M3ML 3LWPB 2PVXA 3M3YL 4XXBB 2PSMC 2RDVA 3GTOL 3HOYL 2WAQP 5K2ME 4B8CD 3S1RL 7RXNA 3LWVB 4TPUA 1RDGA 3I4ML 4A3IL 1CADA 1JYBA 4A93L 2LCQA 3VPBE 4AHWA 2APOB 2XJVA 5IYDL 4A3GL 1R0GA 4TVMA 2XJSA 1I3QL 2V3BB 1PFVA 3KYWA 3FDJA 4ME3A 5JVG1 4POGA 5IP7L 5M3FL 1T9QA 1VCXA 2AQCA 4YWLA 5DM71 4A3LL 2RFKB 1BFYA 1LKPA 2A6HD 2NVTL 1RWDA 3NFPI 1FHMA 3IU3I 5AI3A 1C09A 4QIWP 3RZOL 4U671 1IRNA 3KYVA 3PWFA 2V0FA 3PKJA 2XJTA 3GTPL 2NYDA 1B2JA 2XJUA 3H3VM 1WCML 1TWHL 5M5YL 3GTQL 1P7PA 4LHNA 1IU5A 3HOXL 4C2M1 3ZG6A 5MGNA 5IY0A 2CKAA 4UY81 5GADc 1T9PA 3K35A 1TWFL 5GAEc 1YUXA 2JA6L 1B2OA 2BE5D 2A69D 1TWGL 1DX8A 3H9BA 3H97A 1R9TL 1NXGA 3HOZL 2O5JD 1R0JA 1SMMA 3A44A 1R0IA 5GAGc 4A3FL 1ODHA 4BBSL 4GS7D 2GMGA 1E8JA 3S14L 2CR8A 1S2ZA 3RZ6A 1Y1VL 1QCVA 3MPSA 3GTGL 3HOVL 4AHXA 4V196 4X6AL 3HJWB 2KN9A 2A68D 1OWBA 2Z3RB 2NVYL 4A3CL 4AYBP 4ZN1B 1YUZA 2HR5A 4AR6A 5MF6A 3LPEB 2AYJA 6RXNA 3MSUA 1BE7A 4AI3A 2R92L 3JR7A 3HOWL 2DSXA 3QQCE 1VZIA 1PFWA 2H12A 4A3DL 4G6BA 3GTKL 4BXXL 4C3IL 1Y1WL 2HVYC 2QL0A 2J9UB 3HOUL 5IYCL 2PPTA 3LWRB 1NXEA 1SMWA 3FKIL 2NVQL 4A3EL 3J7Y1 3RZTA 4C3JL 1VZGA 2XJPA 5MFPA 4AI2A 1F4LA 1OWCA 4JAEA 2XJQA 3PIP1 5M5XL 3I4NL 2AUSB 2PVEA 2V0EA 8RXNA 3B0AB 5AN9H 3QVDA 2L0ZA 1Z92B 4A3BL 4Y52L 1LKOA 1YV1A 1NNQA 3H99A 1WJVA 2XJRA 1IROA 4C3HL 1QQTA 5C44L 5EIOC 2JI2A 2ZIXA 1RB9A 1BQ9A 3KYYA 1S30A 4AR3A 3S2HL 3PIO1 5IYBL 5IP9L 1PFUA 4A3KL 4JAFA 3K7AL 4Y7NL 3B08B 1TWAL 2KKDA 1K83L 4AR4A 3S1NL 1CAAA 3S16L 5H1Sc 3PL5A 4BY7L 3S2DL 4ZN3B 3LNLA 5MFZA 3M4OL 5MLC3 1IW7D 3PO2L 4AR5A 4AI1A 3HJYB 2EY4E 4K9FA 2JA7L 3PKIA 1RYQA 2K2DA
chains in the Genus database with same CATH topology
2JA5L 4A3DL 3GTJL 3GTML 2NVTL 3GTKL 4BXXL 4C3IL 2WB1P 2YU9L 1Y1WL 2E2HL 1I50L 4QIWP 3RZOL 5FLML 2VUML 1SFOL 3HOUL 3RZDL 5IYCL 1I6HL 3GTPL 3S17L 3H3VM 1WCML 1TWHL 5M5YL 3GTQL 2E2JL 5C4JL 3HOXL 2B63L 4C2M1 3GTLL 3CQZL 3FKIL 3H0GL 2NVQL 5C3EL 4A3EL 5C4XL 2Y0SP 4C3JL 3S1QL 1TWCL 5M3ML 1TWFL 2R93L 2NVXL 5M5XL 2JA6L 3M3YL 3I4NL 2E2IL 2PMZP 1TWGL 4A3BL 1R9TL 4Y52L 3HOZL 3GTOL 3HOYL 2WAQP 3S1RL 3HKZP 4A3FL 4C3HL 4A3ML 5C44L 4BBSL 3S1ML 3I4ML 4A3IL 4A93L 4BY1L 3S14L 1Y1VL 3GTGL 3HOVL 5IYDL 3S2HL 4A3GL 5IYBL 4X6AL 4BBRL 5IP9L 2JA8L 1I3QL 4A3KL 2R7ZL 4Y7NL 3K7AL 3PO3L 1TWAL 1K83L 2NVYL 4A3CL 4AYBP 3S15L 3S1NL 3S16L 4BY7L 3S2DL 5IP7L 3M4OL 5M3FL 3PO2L 2R92L 4A3JL 2JA7L 5FJ8L 4A3LL 3HOWL 5M5WL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA5 L;  4A3D L;  3GTJ L;  3GTM L;  2NVT L;  3GTK L;  4BXX L;  4C3I L;  2WB1 P;  2YU9 L;  1Y1W L;  2E2H L;  1I50 L;  4QIW P;  3RZO L;  5FLM L;  2VUM L;  1SFO L;  3HOU L;  3RZD L;  5IYC L;  1I6H L;  3GTP L;  3S17 L;  3H3V M;  1WCM L;  1TWH L;  5M5Y L;  3GTQ L;  2E2J L;  5C4J L;  3HOX L;  2B63 L;  4C2M 1;  3GTL L;  3CQZ L;  3FKI L;  3H0G L;  2NVQ L;  5C3E L;  4A3E L;  5C4X L;  2Y0S P;  4C3J L;  3S1Q L;  1TWC L;  5M3M L;  1TWF L;  2R93 L;  2NVX L;  5M5X L;  2JA6 L;  3M3Y L;  3I4N L;  2E2I L;  2PMZ P;  1TWG L;  4A3B L;  1R9T L;  4Y52 L;  3HOZ L;  3GTO L;  3HOY L;  2WAQ P;  3S1R L;  3HKZ P;  4A3F L;  4C3H L;  4A3M L;  5C44 L;  4BBS L;  3S1M L;  3I4M L;  4A3I L;  4A93 L;  4BY1 L;  3S14 L;  1Y1V L;  3GTG L;  3HOV L;  5IYD L;  3S2H L;  4A3G L;  5IYB L;  4X6A L;  4BBR L;  5IP9 L;  2JA8 L;  1I3Q L;  4A3K L;  2R7Z L;  4Y7N L;  3K7A L;  3PO3 L;  1TWA L;  1K83 L;  2NVY L;  4A3C L;  4AYB P;  3S15 L;  3S1N L;  3S16 L;  4BY7 L;  3S2D L;  5IP7 L;  3M4O L;  5M3F L;  3PO2 L;  2R92 L;  4A3J L;  2JA7 L;  5FJ8 L;  4A3L L;  3HOW L;  5M5W L; 
#chains in the Genus database with same CATH topology
 4E6Y A;  4AHY A;  3GTJ L;  1BQ8 A;  2WB1 P;  2JI3 A;  1IU6 A;  2E2H L;  3LWQ B;  2PYA A;  1B13 A;  1H7V A;  2M6O A;  5FLM L;  1SFO L;  2JI1 A;  1T9O A;  3RZD L;  4WFN 1;  4YWM A;  1I6H L;  3S17 L;  4LHL A;  2E2J L;  1LKM A;  4JAG A;  1ZRP A;  2B63 L;  1RDV A;  3GTL L;  4POF A;  3LWO B;  5C3E L;  5C4X L;  1TWC L;  5JVH 1;  3HAX C;  2R93 L;  2NVX L;  3KYX A;  2A6E D;  1SMU A;  1B71 A;  5GAH c;  2E2I L;  2PMZ P;  1YK5 A;  1PFY A;  2C6A A;  4AI0 A;  2M4V A;  3RYG A;  4JAD A;  1BRF A;  1RYT A;  2MS3 A;  1S24 A;  2C6B A;  3HKZ P;  2M4Y A;  1DVB A;  4A3M L;  3S1M L;  3P8B A;  1FHH A;  3SS2 A;  4BY1 L;  1LTL A;  2CKC A;  3WWL A;  4BBR L;  5AI2 A;  2JA8 L;  2R7Z L;  3PO3 L;  3P2A A;  1R0F A;  3PZA A;  2Z3Q B;  1VZH A;  3S15 L;  1PZX A;  2B5I D;  2ERS A;  2ERJ A;  2M6P A;  3MQK B;  4A3J L;  5FJ8 L;  3WWN B;  1R0H A;  5M5W L;  2JA5 L;  3KYU A;  2VL6 A;  3GTM L;  3J7Z 1;  4XGH A;  2YU9 L;  1I50 L;  3H9C A;  2VUM L;  5EIN C;  5DM6 1;  5C4J L;  1QYB A;  4AHZ A;  3CQZ L;  3H0G L;  5RXN A;  1YK4 A;  2Y0S P;  3S1Q L;  4RXN A;  5M3M L;  3LWP B;  2PVX A;  3M3Y L;  4XXB B;  2PSM C;  2RDV A;  3GTO L;  3HOY L;  2WAQ P;  5K2M E;  4B8C D;  3S1R L;  7RXN A;  3LWV B;  4TPU A;  1RDG A;  3I4M L;  4A3I L;  1CAD A;  1JYB A;  4A93 L;  2LCQ A;  3VPB E;  4AHW A;  2APO B;  2XJV A;  5IYD L;  4A3G L;  1R0G A;  4TVM A;  2XJS A;  1I3Q L;  2V3B B;  1PFV A;  3KYW A;  3FDJ A;  4ME3 A;  5JVG 1;  4POG A;  5IP7 L;  5M3F L;  1T9Q A;  1VCX A;  2AQC A;  4YWL A;  5DM7 1;  4A3L L;  2RFK B;  1BFY A;  1LKP A;  2A6H D;  2NVT L;  1RWD A;  3NFP I;  1FHM A;  3IU3 I;  5AI3 A;  1C09 A;  4QIW P;  3RZO L;  4U67 1;  1IRN A;  3KYV A;  3PWF A;  2V0F A;  3PKJ A;  2XJT A;  3GTP L;  2NYD A;  1B2J A;  2XJU A;  3H3V M;  1WCM L;  1TWH L;  5M5Y L;  3GTQ L;  1P7P A;  4LHN A;  1IU5 A;  3HOX L;  4C2M 1;  3ZG6 A;  5MGN A;  5IY0 A;  2CKA A;  4UY8 1;  5GAD c;  1T9P A;  3K35 A;  1TWF L;  5GAE c;  1YUX A;  2JA6 L;  1B2O A;  2BE5 D;  2A69 D;  1TWG L;  1DX8 A;  3H9B A;  3H97 A;  1R9T L;  1NXG A;  3HOZ L;  2O5J D;  1R0J A;  1SMM A;  3A44 A;  1R0I A;  5GAG c;  4A3F L;  1ODH A;  4BBS L;  4GS7 D;  2GMG A;  1E8J A;  3S14 L;  2CR8 A;  1S2Z A;  3RZ6 A;  1Y1V L;  1QCV A;  3MPS A;  3GTG L;  3HOV L;  4AHX A;  4V19 6;  4X6A L;  3HJW B;  2KN9 A;  2A68 D;  1OWB A;  2Z3R B;  2NVY L;  4A3C L;  4AYB P;  4ZN1 B;  1YUZ A;  2HR5 A;  4AR6 A;  5MF6 A;  3LPE B;  2AYJ A;  6RXN A;  3MSU A;  1BE7 A;  4AI3 A;  2R92 L;  3JR7 A;  3HOW L;  2DSX A;  3QQC E;  1VZI A;  1PFW A;  2H12 A;  4A3D L;  4G6B A;  3GTK L;  4BXX L;  4C3I L;  1Y1W L;  2HVY C;  2QL0 A;  2J9U B;  3HOU L;  5IYC L;  2PPT A;  3LWR B;  1NXE A;  1SMW A;  3FKI L;  2NVQ L;  4A3E L;  3J7Y 1;  3RZT A;  4C3J L;  1VZG A;  2XJP A;  5MFP A;  4AI2 A;  1F4L A;  1OWC A;  4JAE A;  2XJQ A;  3PIP 1;  5M5X L;  3I4N L;  2AUS B;  2PVE A;  2V0E A;  8RXN A;  3B0A B;  5AN9 H;  3QVD A;  2L0Z A;  1Z92 B;  4A3B L;  4Y52 L;  1LKO A;  1YV1 A;  1NNQ A;  3H99 A;  1WJV A;  2XJR A;  1IRO A;  4C3H L;  1QQT A;  5C44 L;  5EIO C;  2JI2 A;  2ZIX A;  1RB9 A;  1BQ9 A;  3KYY A;  1S30 A;  4AR3 A;  3S2H L;  3PIO 1;  5IYB L;  5IP9 L;  1PFU A;  4A3K L;  4JAF A;  3K7A L;  4Y7N L;  3B08 B;  1TWA L;  2KKD A;  1K83 L;  4AR4 A;  3S1N L;  1CAA A;  3S16 L;  5H1S c;  3PL5 A;  4BY7 L;  3S2D L;  4ZN3 B;  3LNL A;  5MFZ A;  3M4O L;  5MLC 3;  1IW7 D;  3PO2 L;  4AR5 A;  4AI1 A;  3HJY B;  2EY4 E;  4K9F A;  2JA7 L;  3PKI A;  1RYQ A;  2K2D A; 
#chains in the Genus database with same CATH homology
 2JA5 L;  4A3D L;  3GTJ L;  3GTM L;  2NVT L;  3GTK L;  4BXX L;  4C3I L;  2WB1 P;  2YU9 L;  1Y1W L;  2E2H L;  1I50 L;  4QIW P;  3RZO L;  5FLM L;  2VUM L;  1SFO L;  3HOU L;  3RZD L;  5IYC L;  1I6H L;  3GTP L;  3S17 L;  3H3V M;  1WCM L;  1TWH L;  5M5Y L;  3GTQ L;  2E2J L;  5C4J L;  3HOX L;  2B63 L;  4C2M 1;  3GTL L;  3CQZ L;  3FKI L;  3H0G L;  2NVQ L;  5C3E L;  4A3E L;  5C4X L;  2Y0S P;  4C3J L;  3S1Q L;  1TWC L;  5M3M L;  1TWF L;  2R93 L;  2NVX L;  5M5X L;  2JA6 L;  3M3Y L;  3I4N L;  2E2I L;  2PMZ P;  1TWG L;  4A3B L;  1R9T L;  4Y52 L;  3HOZ L;  3GTO L;  3HOY L;  2WAQ P;  3S1R L;  3HKZ P;  4A3F L;  4C3H L;  4A3M L;  5C44 L;  4BBS L;  3S1M L;  3I4M L;  4A3I L;  4A93 L;  4BY1 L;  3S14 L;  1Y1V L;  3GTG L;  3HOV L;  5IYD L;  3S2H L;  4A3G L;  5IYB L;  4X6A L;  4BBR L;  5IP9 L;  2JA8 L;  1I3Q L;  4A3K L;  2R7Z L;  4Y7N L;  3K7A L;  3PO3 L;  1TWA L;  1K83 L;  2NVY L;  4A3C L;  4AYB P;  3S15 L;  3S1N L;  3S16 L;  4BY7 L;  3S2D L;  5IP7 L;  3M4O L;  5M3F L;  3PO2 L;  2R92 L;  4A3J L;  2JA7 L;  5FJ8 L;  4A3L L;  3HOW L;  5M5W L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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