5J19A

Phospho-pon binding-induced plk1 dimerization
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
223
structure length
221
Chain Sequence
DCHLSDMLQQLHSVNASKPSERVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
pubmed doi rcsb
molecule keywords Serine/threonine-protein kinase PLK1
molecule tags Cell cycle
source organism Homo sapiens
total genus 68
structure length 221
sequence length 223
chains with identical sequence B
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2016-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5j19A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5j19A01
1UMWA 4H71A 5DMSA 4O6WA 4LKMA 4O56A 3HIHA 5DMVC 4X9RA 1Q4OA 4WHLA 4J7BB 5LHZA 3FVHA 4WHKA 3HIKA 4HABA 3BZIA 4RS6A 4E67A 3P37A 4HY2A 4XB0A 3P36A 3C5LA 3Q1IA 2OGQA 4O9WA 4E9DA 4DFWA 4HCOA 4RCPA 5DNJA 3RQ7A 4WHHA 3P34A 4LKLA 3P2WA 3P35A 2OJXA 4X9WA 4H5XA 4X9VA 5J19A 1Q4KA 3P2ZA 2N19A 4E9CA 4YYPA
chains in the Genus database with same CATH superfamily
1UMWA 5DMSA 4LKMA 4O56A 1HDHA 5DMVC 1Q4OA 3LXQA 4WHKA 4HABA 4NK7A 4FDJA 3P36A 2E50A 1FSUA 3Q1IA 2UV8G 2OGQA 1N2LA 4DFWA 4NKBA 3P34A 4G7NA 4LKLA 3P2WA 4H5XA 4N7ZA 1P49A 4YYPA 4O6WA 4X9RA 1E3CP 3BZIA 4N9JA 4XB0A 4CYSA 2I9XA 1E2SP 4HCOA 4RCPA 1E33P 3LM3A 3ED4A 4WHHA 2OJXA 4X9WA 4CYRA 1Q4KA 2N19A 2IA9A 1N2KA 3FS3A 3HIHA 4WHLA 5LHZA 1E2TA 3HIKA 1E1ZP 4RS6A 1A87A 3P37A 3C5LA 2VKZG 4O9WA 4FDIA 5DNJA 5AJ9A 4CXUA 5J19A 4E9CA 4H71A 4N7VA 4J7BB 3FVHA 2QZUA 3GYVA 1F32A 3GYWA 1AUKA 4E67A 4HY2A 3HMJG 4CXSA 4E9DA 1F34B 3RQ7A 3KDRA 3P35A 4X9VA 4CXKA 5DAYA 3P2ZA 2I9ZA 3HFDA
chains in the Genus database with same CATH topology
1UMWA 4H71A 5DMSA 4O6WA 4LKMA 4O56A 3HIHA 5DMVC 4X9RA 1Q4OA 4WHLA 4J7BB 5LHZA 3FVHA 4WHKA 3HIKA 4HABA 3BZIA 4RS6A 4E67A 3P37A 4HY2A 4XB0A 3P36A 3C5LA 3Q1IA 2OGQA 4O9WA 4E9DA 4DFWA 4HCOA 4RCPA 5DNJA 3RQ7A 4WHHA 3P34A 4LKLA 3P2WA 3P35A 2OJXA 4X9WA 4H5XA 4X9VA 5J19A 1Q4KA 3P2ZA 2N19A 4E9CA 4YYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UMW A;  4H71 A;  5DMS A;  4O6W A;  4LKM A;  4O56 A;  3HIH A;  5DMV C;  4X9R A;  1Q4O A;  4WHL A;  4J7B B;  5LHZ A;  3FVH A;  4WHK A;  3HIK A;  4HAB A;  3BZI A;  4RS6 A;  4E67 A;  3P37 A;  4HY2 A;  4XB0 A;  3P36 A;  3C5L A;  3Q1I A;  2OGQ A;  4O9W A;  4E9D A;  4DFW A;  4HCO A;  4RCP A;  5DNJ A;  3RQ7 A;  4WHH A;  3P34 A;  4LKL A;  3P2W A;  3P35 A;  2OJX A;  4X9W A;  4H5X A;  4X9V A;  5J19 A;  1Q4K A;  3P2Z A;  2N19 A;  4E9C A;  4YYP A; 
#chains in the Genus database with same CATH topology
 1UMW A;  5DMS A;  4LKM A;  4O56 A;  1HDH A;  5DMV C;  1Q4O A;  3LXQ A;  4WHK A;  4HAB A;  4NK7 A;  4FDJ A;  3P36 A;  2E50 A;  1FSU A;  3Q1I A;  2UV8 G;  2OGQ A;  1N2L A;  4DFW A;  4NKB A;  3P34 A;  4G7N A;  4LKL A;  3P2W A;  4H5X A;  4N7Z A;  1P49 A;  4YYP A;  4O6W A;  4X9R A;  1E3C P;  3BZI A;  4N9J A;  4XB0 A;  4CYS A;  2I9X A;  1E2S P;  4HCO A;  4RCP A;  1E33 P;  3LM3 A;  3ED4 A;  4WHH A;  2OJX A;  4X9W A;  4CYR A;  1Q4K A;  2N19 A;  2IA9 A;  1N2K A;  3FS3 A;  3HIH A;  4WHL A;  5LHZ A;  1E2T A;  3HIK A;  1E1Z P;  4RS6 A;  1A87 A;  3P37 A;  3C5L A;  2VKZ G;  4O9W A;  4FDI A;  5DNJ A;  5AJ9 A;  4CXU A;  5J19 A;  4E9C A;  4H71 A;  4N7V A;  4J7B B;  3FVH A;  2QZU A;  3GYV A;  1F32 A;  3GYW A;  1AUK A;  4E67 A;  4HY2 A;  3HMJ G;  4CXS A;  4E9D A;  1F34 B;  3RQ7 A;  3KDR A;  3P35 A;  4X9V A;  4CXK A;  5DAY A;  3P2Z A;  2I9Z A;  3HFD A; 
#chains in the Genus database with same CATH homology
 1UMW A;  4H71 A;  5DMS A;  4O6W A;  4LKM A;  4O56 A;  3HIH A;  5DMV C;  4X9R A;  1Q4O A;  4WHL A;  4J7B B;  5LHZ A;  3FVH A;  4WHK A;  3HIK A;  4HAB A;  3BZI A;  4RS6 A;  4E67 A;  3P37 A;  4HY2 A;  4XB0 A;  3P36 A;  3C5L A;  3Q1I A;  2OGQ A;  4O9W A;  4E9D A;  4DFW A;  4HCO A;  4RCP A;  5DNJ A;  3RQ7 A;  4WHH A;  3P34 A;  4LKL A;  3P2W A;  3P35 A;  2OJX A;  4X9W A;  4H5X A;  4X9V A;  5J19 A;  1Q4K A;  3P2Z A;  2N19 A;  4E9C A;  4YYP A; 
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similar chains in the Genus database (?% sequence similarity)
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