5J19A

Phospho-pon binding-induced plk1 dimerization
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
223
structure length
221
Chain Sequence
DCHLSDMLQQLHSVNASKPSERVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
pubmed doi rcsb
source organism Homo sapiens
molecule tags Cell cycle
molecule keywords Serine/threonine-protein kinase PLK1
total genus 68
structure length 221
sequence length 223
chains with identical sequence B
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2016-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5j19A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5j19A01
4WHKA 3BZIA 5LHZA 2OJXA 5DMSA 1Q4KA 3P35A 3FVHA 5DMVC 4LKMA 4HY2A 4H71A 4XB0A 4H5XA 4X9RA 3P2ZA 4E9DA 3HIKA 3P36A 4O6WA 4O56A 4YYPA 3Q1IA 4HCOA 3P37A 3RQ7A 4HABA 4RCPA 4RS6A 4O9WA 4X9WA 4E67A 4WHLA 3P2WA 2OGQA 4E9CA 5J19A 3P34A 1UMWA 4WHHA 4DFWA 4J7BB 4LKLA 5DNJA 4X9VA 2N19A 3HIHA 3C5LA 1Q4OA
chains in the Genus database with same CATH superfamily
5LHZA 5DAYA 2QZUA 3P35A 5DMVC 4LKMA 2E50A 4N7ZA 4XB0A 2UV8G 2IA9A 3P2ZA 4E9DA 4CXKA 1A87A 1E33P 3KDRA 3RQ7A 4HABA 4X9WA 4NK7A 4O9WA 2I9XA 4E67A 3P34A 4CYSA 4WHHA 2VKZG 4DFWA 1N2KA 5DNJA 4X9VA 3C5LA 1Q4OA 4WHKA 3GYWA 4NKBA 4CYRA 4FDJA 3ED4A 2I9ZA 4X9RA 1P49A 3GYVA 3HIKA 4FDIA 4O56A 4HCOA 3P37A 5AJ9A 3P2WA 4E9CA 3HIHA 2OJXA 1Q4KA 3FVHA 4H71A 4H5XA 1N2LA 3LM3A 4CXSA 4CXUA 4RS6A 1HDHA 2OGQA 1E1ZP 4J7BB 3HMJG 2N19A 4G7NA 4N7VA 3BZIA 5DMSA 3HFDA 3LXQA 4HY2A 3FS3A 1F34B 3P36A 4O6WA 4N9JA 4YYPA 3Q1IA 4RCPA 1AUKA 4WHLA 1E3CP 5J19A 1E2SP 1UMWA 1FSUA 4LKLA 1F32A 1E2TA
chains in the Genus database with same CATH topology
4WHKA 3BZIA 5LHZA 2OJXA 5DMSA 1Q4KA 3P35A 3FVHA 5DMVC 4LKMA 4HY2A 4H71A 4XB0A 4H5XA 4X9RA 3P2ZA 4E9DA 3HIKA 3P36A 4O6WA 4O56A 4YYPA 3Q1IA 4HCOA 3P37A 3RQ7A 4HABA 4RCPA 4RS6A 4O9WA 4X9WA 4E67A 4WHLA 3P2WA 2OGQA 4E9CA 5J19A 3P34A 1UMWA 4WHHA 4DFWA 4J7BB 4LKLA 5DNJA 4X9VA 2N19A 3HIHA 3C5LA 1Q4OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WHK A;  3BZI A;  5LHZ A;  2OJX A;  5DMS A;  1Q4K A;  3P35 A;  3FVH A;  5DMV C;  4LKM A;  4HY2 A;  4H71 A;  4XB0 A;  4H5X A;  4X9R A;  3P2Z A;  4E9D A;  3HIK A;  3P36 A;  4O6W A;  4O56 A;  4YYP A;  3Q1I A;  4HCO A;  3P37 A;  3RQ7 A;  4HAB A;  4RCP A;  4RS6 A;  4O9W A;  4X9W A;  4E67 A;  4WHL A;  3P2W A;  2OGQ A;  4E9C A;  5J19 A;  3P34 A;  1UMW A;  4WHH A;  4DFW A;  4J7B B;  4LKL A;  5DNJ A;  4X9V A;  2N19 A;  3HIH A;  3C5L A;  1Q4O A; 
#chains in the Genus database with same CATH topology
 5LHZ A;  5DAY A;  2QZU A;  3P35 A;  5DMV C;  4LKM A;  2E50 A;  4N7Z A;  4XB0 A;  2UV8 G;  2IA9 A;  3P2Z A;  4E9D A;  4CXK A;  1A87 A;  1E33 P;  3KDR A;  3RQ7 A;  4HAB A;  4X9W A;  4NK7 A;  4O9W A;  2I9X A;  4E67 A;  3P34 A;  4CYS A;  4WHH A;  2VKZ G;  4DFW A;  1N2K A;  5DNJ A;  4X9V A;  3C5L A;  1Q4O A;  4WHK A;  3GYW A;  4NKB A;  4CYR A;  4FDJ A;  3ED4 A;  2I9Z A;  4X9R A;  1P49 A;  3GYV A;  3HIK A;  4FDI A;  4O56 A;  4HCO A;  3P37 A;  5AJ9 A;  3P2W A;  4E9C A;  3HIH A;  2OJX A;  1Q4K A;  3FVH A;  4H71 A;  4H5X A;  1N2L A;  3LM3 A;  4CXS A;  4CXU A;  4RS6 A;  1HDH A;  2OGQ A;  1E1Z P;  4J7B B;  3HMJ G;  2N19 A;  4G7N A;  4N7V A;  3BZI A;  5DMS A;  3HFD A;  3LXQ A;  4HY2 A;  3FS3 A;  1F34 B;  3P36 A;  4O6W A;  4N9J A;  4YYP A;  3Q1I A;  4RCP A;  1AUK A;  4WHL A;  1E3C P;  5J19 A;  1E2S P;  1UMW A;  1FSU A;  4LKL A;  1F32 A;  1E2T A; 
#chains in the Genus database with same CATH homology
 4WHK A;  3BZI A;  5LHZ A;  2OJX A;  5DMS A;  1Q4K A;  3P35 A;  3FVH A;  5DMV C;  4LKM A;  4HY2 A;  4H71 A;  4XB0 A;  4H5X A;  4X9R A;  3P2Z A;  4E9D A;  3HIK A;  3P36 A;  4O6W A;  4O56 A;  4YYP A;  3Q1I A;  4HCO A;  3P37 A;  3RQ7 A;  4HAB A;  4RCP A;  4RS6 A;  4O9W A;  4X9W A;  4E67 A;  4WHL A;  3P2W A;  2OGQ A;  4E9C A;  5J19 A;  3P34 A;  1UMW A;  4WHH A;  4DFW A;  4J7B B;  4LKL A;  5DNJ A;  4X9V A;  2N19 A;  3HIH A;  3C5L A;  1Q4O A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...