5J31A

Crystal structure of 14-3-3zeta in complex with an alkyne cross-linked cyclic peptide derived from exos
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
230
structure length
229
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 100
structure length 229
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5j31A00
3P1QA 1O9EA 3SMKA 3U9XA 4DHRA 3O8IA 5LVZA 1YWTA 3P1PA 2C1NA 2BR9A 4DHPA 4FL5A 3SPRA 3P1RA 2C63A 3M50A 4QLIA 4N84A 2C1JA 4DHQA 5LU1A 4DHNA 2B05A 3SMNA 4J6SA 2WH0A 5BY9A 1O9CA 3UBWA 4N7YA 5D3EA 4DATA 1A38A 5EWZA 3SMLA 4JC3A 3UZDA 4JDDA 5LX2A 4DHMA 1A37A 3T0MA 2O8PA 4Y32A 5IQPA 3UALA 3EFZA 1O9FA 4N7GA 4DNKA 4FR3A 3P1SA 2BQ0A 1A4OA 5D2DA 3P1NA 5EXAA 1QJAA 4DHOA 4DHUA 4ZQ0A 3UX0A 1YZ5A 2BTPA 3LW1A 3MHRA 3E6YA 3SP5A 2O02A 3SMMA 4ZDRA 4GNTA 3IQVA 4DX0A 2O98A 4DHSA 1QJBA 3M51A 5LU2A 4F7RA 4WRQA 1IB1A 5F74A 3P1OA 4IHLA 5LHOA 3RDHA 1O9DA 3SMOA 5BTVA 4HKCA 5HF3A 3NKXA 3IQJA 3T0LA 4DAUA 2V7DA 3AXYC 4O46A 4BG6A 4IEAA 4DHTA 3IQUA 4Y5IA 5J31A 5D3FA 4Y3BA 2C74A 2C23A 3CU8A 4FJ3A 4E2EA 2NPMA
chains in the Genus database with same CATH superfamily
3P1QA 1O9EA 3SMKA 1URJA 3U9XA 4DHRA 3O8IA 5LVZA 1YWTA 3P1PA 2C1NA 2BR9A 4DHPA 4FL5A 3SPRA 3P1RA 2C63A 3M50A 4QLIA 4N84A 2C1JA 4DHQA 5LU1A 4DHNA 2B05A 3SMNA 4J6SA 2WH0A 5BY9A 1O9CA 3UBWA 4N7YA 5D3EA 4DATA 1A38A 3EB7A 5EWZA 3SMLA 4QX3A 4JC3A 4ARXA 3UZDA 4JDDA 5LX2A 4DHMA 1A37A 3T0MA 4QX1A 2O8PA 4Y32A 5IQPA 3UALA 4W8JA 3EFZA 1O9FA 4N7GA 4DNKA 3ZHEB 4FR3A 3P1SA 2BQ0A 1A4OA 5D2DA 3P1NA 5EXAA 1JI6A 1QJAA 1DLCA 4DHOA 4DHUA 4ZQ0A 3UX0A 1YZ5A 2BTPA 3LW1A 3MHRA 3E6YA 4QX0A 1W99A 3CQGA 3SP5A 2O02A 3SMMA 3I4RA 4ZDRA 4GNTA 3IQVA 4DX0A 2O98A 4QX2A 4DHSA 1QJBA 3X0UA 4MOAA 3M51A 1I5PA 5LU2A 4F7RA 1S2XA 1CIYA 4WRQA 1IB1A 5F74A 3P1OA 4IHLA 5LHOA 3RDHA 1O9DA 3SMOA 5BTVA 4HKCA 5HF3A 2C9KA 3NKXA 3IQJA 3T0LA 4DAUA 4D8MA 2V7DA 3AXYC 3CQCA 4O46A 4BG6A 4IEAA 4ARYA 4DHTA 3IQUA 4Y5IA 5J31A 5D3FA 4Y3BA 2C74A 2C23A 3CU8A 4FJ3A 4E2EA 2NPMA
chains in the Genus database with same CATH topology
3P1QA 1O9EA 3SMKA 3U9XA 4DHRA 3O8IA 5LVZA 1YWTA 3P1PA 2C1NA 2BR9A 4DHPA 4FL5A 3SPRA 3P1RA 2C63A 3M50A 4QLIA 4N84A 2C1JA 4DHQA 5LU1A 4DHNA 2B05A 3SMNA 4J6SA 2WH0A 5BY9A 1O9CA 3UBWA 4N7YA 5D3EA 4DATA 1A38A 5EWZA 3SMLA 4JC3A 3UZDA 4JDDA 5LX2A 4DHMA 1A37A 3T0MA 2O8PA 4Y32A 5IQPA 3UALA 3EFZA 1O9FA 4N7GA 4DNKA 4FR3A 3P1SA 2BQ0A 1A4OA 5D2DA 3P1NA 5EXAA 1QJAA 4DHOA 4DHUA 4ZQ0A 3UX0A 1YZ5A 2BTPA 3LW1A 3MHRA 3E6YA 3SP5A 2O02A 3SMMA 4ZDRA 4GNTA 3IQVA 4DX0A 2O98A 4DHSA 1QJBA 3M51A 5LU2A 4F7RA 4WRQA 1IB1A 5F74A 3P1OA 4IHLA 5LHOA 3RDHA 1O9DA 3SMOA 5BTVA 4HKCA 5HF3A 3NKXA 3IQJA 3T0LA 4DAUA 2V7DA 3AXYC 4O46A 4BG6A 4IEAA 4DHTA 3IQUA 4Y5IA 5J31A 5D3FA 4Y3BA 2C74A 2C23A 3CU8A 4FJ3A 4E2EA 2NPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P1Q A;  1O9E A;  3SMK A;  3U9X A;  4DHR A;  3O8I A;  5LVZ A;  1YWT A;  3P1P A;  2C1N A;  2BR9 A;  4DHP A;  4FL5 A;  3SPR A;  3P1R A;  2C63 A;  3M50 A;  4QLI A;  4N84 A;  2C1J A;  4DHQ A;  5LU1 A;  4DHN A;  2B05 A;  3SMN A;  4J6S A;  2WH0 A;  5BY9 A;  1O9C A;  3UBW A;  4N7Y A;  5D3E A;  4DAT A;  1A38 A;  5EWZ A;  3SML A;  4JC3 A;  3UZD A;  4JDD A;  5LX2 A;  4DHM A;  1A37 A;  3T0M A;  2O8P A;  4Y32 A;  5IQP A;  3UAL A;  3EFZ A;  1O9F A;  4N7G A;  4DNK A;  4FR3 A;  3P1S A;  2BQ0 A;  1A4O A;  5D2D A;  3P1N A;  5EXA A;  1QJA A;  4DHO A;  4DHU A;  4ZQ0 A;  3UX0 A;  1YZ5 A;  2BTP A;  3LW1 A;  3MHR A;  3E6Y A;  3SP5 A;  2O02 A;  3SMM A;  4ZDR A;  4GNT A;  3IQV A;  4DX0 A;  2O98 A;  4DHS A;  1QJB A;  3M51 A;  5LU2 A;  4F7R A;  4WRQ A;  1IB1 A;  5F74 A;  3P1O A;  4IHL A;  5LHO A;  3RDH A;  1O9D A;  3SMO A;  5BTV A;  4HKC A;  5HF3 A;  3NKX A;  3IQJ A;  3T0L A;  4DAU A;  2V7D A;  3AXY C;  4O46 A;  4BG6 A;  4IEA A;  4DHT A;  3IQU A;  4Y5I A;  5J31 A;  5D3F A;  4Y3B A;  2C74 A;  2C23 A;  3CU8 A;  4FJ3 A;  4E2E A;  2NPM A; 
#chains in the Genus database with same CATH topology
 3P1Q A;  1O9E A;  3SMK A;  1URJ A;  3U9X A;  4DHR A;  3O8I A;  5LVZ A;  1YWT A;  3P1P A;  2C1N A;  2BR9 A;  4DHP A;  4FL5 A;  3SPR A;  3P1R A;  2C63 A;  3M50 A;  4QLI A;  4N84 A;  2C1J A;  4DHQ A;  5LU1 A;  4DHN A;  2B05 A;  3SMN A;  4J6S A;  2WH0 A;  5BY9 A;  1O9C A;  3UBW A;  4N7Y A;  5D3E A;  4DAT A;  1A38 A;  3EB7 A;  5EWZ A;  3SML A;  4QX3 A;  4JC3 A;  4ARX A;  3UZD A;  4JDD A;  5LX2 A;  4DHM A;  1A37 A;  3T0M A;  4QX1 A;  2O8P A;  4Y32 A;  5IQP A;  3UAL A;  4W8J A;  3EFZ A;  1O9F A;  4N7G A;  4DNK A;  3ZHE B;  4FR3 A;  3P1S A;  2BQ0 A;  1A4O A;  5D2D A;  3P1N A;  5EXA A;  1JI6 A;  1QJA A;  1DLC A;  4DHO A;  4DHU A;  4ZQ0 A;  3UX0 A;  1YZ5 A;  2BTP A;  3LW1 A;  3MHR A;  3E6Y A;  4QX0 A;  1W99 A;  3CQG A;  3SP5 A;  2O02 A;  3SMM A;  3I4R A;  4ZDR A;  4GNT A;  3IQV A;  4DX0 A;  2O98 A;  4QX2 A;  4DHS A;  1QJB A;  3X0U A;  4MOA A;  3M51 A;  1I5P A;  5LU2 A;  4F7R A;  1S2X A;  1CIY A;  4WRQ A;  1IB1 A;  5F74 A;  3P1O A;  4IHL A;  5LHO A;  3RDH A;  1O9D A;  3SMO A;  5BTV A;  4HKC A;  5HF3 A;  2C9K A;  3NKX A;  3IQJ A;  3T0L A;  4DAU A;  4D8M A;  2V7D A;  3AXY C;  3CQC A;  4O46 A;  4BG6 A;  4IEA A;  4ARY A;  4DHT A;  3IQU A;  4Y5I A;  5J31 A;  5D3F A;  4Y3B A;  2C74 A;  2C23 A;  3CU8 A;  4FJ3 A;  4E2E A;  2NPM A; 
#chains in the Genus database with same CATH homology
 3P1Q A;  1O9E A;  3SMK A;  3U9X A;  4DHR A;  3O8I A;  5LVZ A;  1YWT A;  3P1P A;  2C1N A;  2BR9 A;  4DHP A;  4FL5 A;  3SPR A;  3P1R A;  2C63 A;  3M50 A;  4QLI A;  4N84 A;  2C1J A;  4DHQ A;  5LU1 A;  4DHN A;  2B05 A;  3SMN A;  4J6S A;  2WH0 A;  5BY9 A;  1O9C A;  3UBW A;  4N7Y A;  5D3E A;  4DAT A;  1A38 A;  5EWZ A;  3SML A;  4JC3 A;  3UZD A;  4JDD A;  5LX2 A;  4DHM A;  1A37 A;  3T0M A;  2O8P A;  4Y32 A;  5IQP A;  3UAL A;  3EFZ A;  1O9F A;  4N7G A;  4DNK A;  4FR3 A;  3P1S A;  2BQ0 A;  1A4O A;  5D2D A;  3P1N A;  5EXA A;  1QJA A;  4DHO A;  4DHU A;  4ZQ0 A;  3UX0 A;  1YZ5 A;  2BTP A;  3LW1 A;  3MHR A;  3E6Y A;  3SP5 A;  2O02 A;  3SMM A;  4ZDR A;  4GNT A;  3IQV A;  4DX0 A;  2O98 A;  4DHS A;  1QJB A;  3M51 A;  5LU2 A;  4F7R A;  4WRQ A;  1IB1 A;  5F74 A;  3P1O A;  4IHL A;  5LHO A;  3RDH A;  1O9D A;  3SMO A;  5BTV A;  4HKC A;  5HF3 A;  3NKX A;  3IQJ A;  3T0L A;  4DAU A;  2V7D A;  3AXY C;  4O46 A;  4BG6 A;  4IEA A;  4DHT A;  3IQU A;  4Y5I A;  5J31 A;  5D3F A;  4Y3B A;  2C74 A;  2C23 A;  3CU8 A;  4FJ3 A;  4E2E A;  2NPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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