5JDPA

E73v mutant of the human voltage-dependent anion channel
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
285
structure length
285
Chain Sequence
SAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTVKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQARS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Membrane protein
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 56
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2016-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 5jdpA00
2K4TA 1MPFA 2QTKA 2FGQX 3T0SA 2Y0HA 2J1NA 6PRNA 5DL8A 1E54A 4LSEA 4KR8A 4D65A 2Y0KA 4D64A 1HXTA 1OPFA 4AUIA 7PRNA 2PRNA 3SZDA 2XE3A 4FRXA 4GCSA 4LSIA 2O4VA 4BUMX 4KRAA 4KR4A 3VY8X 3WI5A 3VZWX 1GFMA 1PRNA 2FGRA 2J4UP 8PRNA 5JDPA 3VY9X 2XE2A 1GFOA 3HW9A 2XG6A 1PHOA 3VZTX 3EMNX 5DL6A 1BH3A 4FSPA 3SY9A 3T24A 2Y2XA 2PORA 4FT6A 3HWBA 3NSGA 3SY7A 3K19A 1HXUA 1GFQA 3WI4A 4FMSA 2OMFA 4FRTA 4LSFA 5FVNA 3SYBA 1HXXA 3POXA 5DL7A 4JFBA 3PORA 1GFPA 3O0EA 3UU2A 4LSHA 4FOZA 3SYSA 1H6S1 2ZFGA 3POQA 5PRNA 3A2SX 3UPGA 2Y0LA 3PRNA 2ODJA 4GCPA 3SZVA 2XE1A 5DL5A 3VZUX 4C69X 1GFNA 1BT9A 3JTYA 3T20A 3FYXA 4GCQA 4RJXA 2ZLDA 4D5UA 3POUA 4FSOA 2XE5A 1OSMA 4RJWA
chains in the Genus database with same CATH superfamily
1T1LA 3UAQA 2K4TA 3G7GA 2YPVA 1MPFA 4O3YA 4RLCA 2QTKA 3AA7A 3PQSA 4E1TA 2FGQX 1S5LO 4O4UA 3T0SA 2Y0HA 2J1NA 1P4TA 6PRNA 5DL8A 3TZGA 3A0HO 2N2LA 4PUXA 5H2FO 1E54A 4LSEA 4KR8A 4D65A 2LFUA 2Y0KA 4D64A 5ADXL 1HXTA 1OPFA 4AUIA 2XMXA 5B66O 1YS5A 3DWOX 4AYDC 4Z3TA 7PRNA 2PRNA 5KAFO 1THQA 3SZDA 2XE3A 4FRXA 4GCSA 4AYID 4GF4A 2O4VA 3PGUA 4LSIA 5EE2A 4AYNA 4BUMX 3DA3A 3DWNA 3PGRA 4U9CA 4UB6O 4KRAA 3V8UA 3JCUO 4N75A 4KR4A 3VY8X 3WI5A 4QQ1A 4N59A 3NJTA 3VZWX 1IZNA 1GFMA 2R8AA 2GE4A 4FZMA 4O3WA 3DZMA 1PRNA 4FQEA 2FGRA 4O4XA 4K3CA 2R4OA 3PQUA 4N58A 4E1SA 2J4UP 4K3BA 4RLBA 4O49A 1QJ9A 3C5OA 8PRNA 3AAAB 2W81C 5JDPA 3VY9X 2XE2A 1GFOA 3HW9A 3KZIO 2XG6A 4AYMC 4AYEC 1PHOA 3KVDD 5G3AA 4GHBA 3VZTX 1QJPA 1Q9FA 4F4BA 4C00A 3EMNX 5DL6A 1BH3A 4FESA 2KXPA 4FSPA 3AA7B 1ZHYA 2R88A 2K0LA 1G90A 3RBHA 3SY9A 4AKRA 4O3ZA 3T24A 2KXPB 2Y2XA 2IWWA 5D5DA 5ADXK 3LK2B 4JCHA 5TISO 2PORA 4FT6A 5GTHO 3HWBA 3LK2A 3NSGA 1QJ8A 5G26A 1BXWA 1MM5A 3SY7A 1ZHWA 3LK42 3PF1A 3AAAA 2M07A 2WVPA 4PR7A 4AKRB 2KDYA 5AFUK 2R4NA 3K19A 1HXUA 1GFQA 4PJ0O 3AA0A 4CTDA 2X27X 1ZHZA 2WJQA 4FMSA 3WI4A 2OMFA 4FRTA 2JQYA 4RL9A 5G38A 4LSFA 4XNKA 4AFKA 2AXTO 5FVNA 2KZ7B 3QRCA 2JMMA 2N2MA 3SYBA 1HXXA 3POXA 3QRAA 2IWVA 2F1VA 4XNLA 5DL7A 2MNHA 4JFBA 3VE2A 2MHLA 3PORA 2F1TA 1GFPA 1IZNB 2KC0A 4FZLA 5IYUA 3GP6A 3AA1A 1Q9GA 2M06A 1ORMA 4B61A 3O0EA 2YNKA 3UU2A 2R4PA 4G76A 4LSHA 4FOZA 3HOEA 3SYSA 4FZNA 1H6S1 2ZFGA 3A0BO 3HOLA 3POQA 1MM4A 5PRNA 3A2SX 3UPGA 3BS0A 3DA4A 5B5EO 2Y7SA 2Y0LA 4N74A 4IL6O 4O3XB 3PRNA 5GTIO 5AFUL 4G75A 2X9KA 3VE1A 4C4VB 2ODJA 4GCPA 5KAIO 3AAEB 3LK3A 3SZVA 5GV0A 3BRZA 2XE1A 5DL5A 5G39A 3VZUX 3AA1B 4AKMA 3PGSA 4C69X 2R4LA 3BRYA 2XTQA 1GFNA 1BT9A 4AZLA 2W80C 3JTYA 2ERVA 2R89A 1T16A 3T20A 2KZ7A 5E79O 4UB8O 3FYXA 4RJWA 3AA6B 4GCQA 4RJXA 1ZHTA 2WJRA 2XTRA 2ZLDA 4D5UA 3POUA 2LHFA 5T5FA 3AA6A 3WU2O 4C4VA 3AAEA 3LK41 2XE5A 1OSMA 3AA0B 3LK3B 1ZHXA 4FSOA 2F1CX 4FUVA
chains in the Genus database with same CATH topology
3UAQA 2K4TA 3G7GA 2YPVA 1MPFA 4O3YA 4RLCA 2QTKA 3AA7A 3PQSA 4E1TA 2FGQX 4O4UA 3T0SA 2Y0HA 2J1NA 1P4TA 6PRNA 5DL8A 3TZGA 2N2LA 4PUXA 1E54A 4LSEA 4KR8A 4D65A 2LFUA 2Y0KA 4D64A 5ADXL 1HXTA 1OPFA 4AUIA 2XMXA 1YS5A 4AYDC 4Z3TA 7PRNA 2PRNA 1THQA 3SZDA 2XE3A 4FRXA 4GCSA 4AYID 4GF4A 2O4VA 4LSIA 5EE2A 4AYNA 4BUMX 3DA3A 4U9CA 3V8UA 4KRAA 4KR4A 3VY8X 3WI5A 4QQ1A 4N59A 3VZWX 1IZNA 1GFMA 2GE4A 4FZMA 4O3WA 4O4XA 1PRNA 4E1SA 2FGRA 3PQUA 2J4UP 4N58A 4RLBA 4O49A 1QJ9A 3C5OA 8PRNA 3AAAB 2W81C 5JDPA 3VY9X 2XE2A 1GFOA 3HW9A 2XG6A 4AYMC 4AYEC 1PHOA 3KVDD 3VZTX 4GHBA 1QJPA 1Q9FA 4F4BA 3EMNX 5DL6A 1BH3A 4FESA 2KXPA 4FSPA 3AA7B 1ZHYA 1G90A 2K0LA 3RBHA 3SY9A 4AKRA 4O3ZA 3T24A 2KXPB 2Y2XA 5D5DA 5ADXK 3LK2B 4JCHA 2PORA 4FT6A 3HWBA 3LK2A 3NSGA 1QJ8A 5G26A 1BXWA 1MM5A 3SY7A 1ZHWA 3LK42 4AKRB 3AAAA 2M07A 5AFUK 2KDYA 3K19A 1HXUA 1GFQA 3AA0A 2X27X 1ZHZA 4FMSA 3WI4A 2OMFA 4FRTA 4RL9A 4LSFA 4XNKA 4AFKA 5FVNA 2KZ7B 3QRCA 2JMMA 2N2MA 3SYBA 1HXXA 3POXA 3QRAA 5DL7A 2F1VA 4XNLA 2MNHA 4JFBA 3VE2A 2MHLA 3PORA 2F1TA 1GFPA 1IZNB 2KC0A 4FZLA 5IYUA 3GP6A 3AA1A 1Q9GA 2M06A 1ORMA 4B61A 3O0EA 2YNKA 3UU2A 4LSHA 4G76A 4FOZA 3HOEA 3SYSA 4FZNA 1H6S1 2ZFGA 3HOLA 3POQA 1MM4A 5PRNA 3A2SX 3UPGA 3DA4A 2Y7SA 2Y0LA 4O3XB 3PRNA 5AFUL 4G75A 3VE1A 2ODJA 4GCPA 3SZVA 3AAEB 3LK3A 5GV0A 2XE1A 5DL5A 3VZUX 4AKMA 3AA1B 4C69X 2XTQA 1GFNA 1BT9A 4AZLA 2W80C 3JTYA 2ERVA 3T20A 2KZ7A 3FYXA 4RJWA 3AA6B 4GCQA 4RJXA 1ZHTA 2XTRA 2ZLDA 4D5UA 3POUA 2LHFA 5T5FA 3AA6A 3AAEA 3LK41 2XE5A 1OSMA 3AA0B 3LK3B 1ZHXA 4FSOA 4FUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K4T A;  1MPF A;  2QTK A;  2FGQ X;  3T0S A;  2Y0H A;  2J1N A;  6PRN A;  5DL8 A;  1E54 A;  4LSE A;  4KR8 A;  4D65 A;  2Y0K A;  4D64 A;  1HXT A;  1OPF A;  4AUI A;  7PRN A;  2PRN A;  3SZD A;  2XE3 A;  4FRX A;  4GCS A;  4LSI A;  2O4V A;  4BUM X;  4KRA A;  4KR4 A;  3VY8 X;  3WI5 A;  3VZW X;  1GFM A;  1PRN A;  2FGR A;  2J4U P;  8PRN A;  5JDP A;  3VY9 X;  2XE2 A;  1GFO A;  3HW9 A;  2XG6 A;  1PHO A;  3VZT X;  3EMN X;  5DL6 A;  1BH3 A;  4FSP A;  3SY9 A;  3T24 A;  2Y2X A;  2POR A;  4FT6 A;  3HWB A;  3NSG A;  3SY7 A;  3K19 A;  1HXU A;  1GFQ A;  3WI4 A;  4FMS A;  2OMF A;  4FRT A;  4LSF A;  5FVN A;  3SYB A;  1HXX A;  3POX A;  5DL7 A;  4JFB A;  3POR A;  1GFP A;  3O0E A;  3UU2 A;  4LSH A;  4FOZ A;  3SYS A;  1H6S 1;  2ZFG A;  3POQ A;  5PRN A;  3A2S X;  3UPG A;  2Y0L A;  3PRN A;  2ODJ A;  4GCP A;  3SZV A;  2XE1 A;  5DL5 A;  3VZU X;  4C69 X;  1GFN A;  1BT9 A;  3JTY A;  3T20 A;  3FYX A;  4GCQ A;  4RJX A;  2ZLD A;  4D5U A;  3POU A;  4FSO A;  2XE5 A;  1OSM A;  4RJW A; 
#chains in the Genus database with same CATH topology
 1T1L A;  3UAQ A;  2K4T A;  3G7G A;  2YPV A;  1MPF A;  4O3Y A;  4RLC A;  2QTK A;  3AA7 A;  3PQS A;  4E1T A;  2FGQ X;  1S5L O;  4O4U A;  3T0S A;  2Y0H A;  2J1N A;  1P4T A;  6PRN A;  5DL8 A;  3TZG A;  3A0H O;  2N2L A;  4PUX A;  5H2F O;  1E54 A;  4LSE A;  4KR8 A;  4D65 A;  2LFU A;  2Y0K A;  4D64 A;  5ADX L;  1HXT A;  1OPF A;  4AUI A;  2XMX A;  5B66 O;  1YS5 A;  3DWO X;  4AYD C;  4Z3T A;  7PRN A;  2PRN A;  5KAF O;  1THQ A;  3SZD A;  2XE3 A;  4FRX A;  4GCS A;  4AYI D;  4GF4 A;  2O4V A;  3PGU A;  4LSI A;  5EE2 A;  4AYN A;  4BUM X;  3DA3 A;  3DWN A;  3PGR A;  4U9C A;  4UB6 O;  4KRA A;  3V8U A;  3JCU O;  4N75 A;  4KR4 A;  3VY8 X;  3WI5 A;  4QQ1 A;  4N59 A;  3NJT A;  3VZW X;  1IZN A;  1GFM A;  2R8A A;  2GE4 A;  4FZM A;  4O3W A;  3DZM A;  1PRN A;  4FQE A;  2FGR A;  4O4X A;  4K3C A;  2R4O A;  3PQU A;  4N58 A;  4E1S A;  2J4U P;  4K3B A;  4RLB A;  4O49 A;  1QJ9 A;  3C5O A;  8PRN A;  3AAA B;  2W81 C;  5JDP A;  3VY9 X;  2XE2 A;  1GFO A;  3HW9 A;  3KZI O;  2XG6 A;  4AYM C;  4AYE C;  1PHO A;  3KVD D;  5G3A A;  4GHB A;  3VZT X;  1QJP A;  1Q9F A;  4F4B A;  4C00 A;  3EMN X;  5DL6 A;  1BH3 A;  4FES A;  2KXP A;  4FSP A;  3AA7 B;  1ZHY A;  2R88 A;  2K0L A;  1G90 A;  3RBH A;  3SY9 A;  4AKR A;  4O3Z A;  3T24 A;  2KXP B;  2Y2X A;  2IWW A;  5D5D A;  5ADX K;  3LK2 B;  4JCH A;  5TIS O;  2POR A;  4FT6 A;  5GTH O;  3HWB A;  3LK2 A;  3NSG A;  1QJ8 A;  5G26 A;  1BXW A;  1MM5 A;  3SY7 A;  1ZHW A;  3LK4 2;  3PF1 A;  3AAA A;  2M07 A;  2WVP A;  4PR7 A;  4AKR B;  2KDY A;  5AFU K;  2R4N A;  3K19 A;  1HXU A;  1GFQ A;  4PJ0 O;  3AA0 A;  4CTD A;  2X27 X;  1ZHZ A;  2WJQ A;  4FMS A;  3WI4 A;  2OMF A;  4FRT A;  2JQY A;  4RL9 A;  5G38 A;  4LSF A;  4XNK A;  4AFK A;  2AXT O;  5FVN A;  2KZ7 B;  3QRC A;  2JMM A;  2N2M A;  3SYB A;  1HXX A;  3POX A;  3QRA A;  2IWV A;  2F1V A;  4XNL A;  5DL7 A;  2MNH A;  4JFB A;  3VE2 A;  2MHL A;  3POR A;  2F1T A;  1GFP A;  1IZN B;  2KC0 A;  4FZL A;  5IYU A;  3GP6 A;  3AA1 A;  1Q9G A;  2M06 A;  1ORM A;  4B61 A;  3O0E A;  2YNK A;  3UU2 A;  2R4P A;  4G76 A;  4LSH A;  4FOZ A;  3HOE A;  3SYS A;  4FZN A;  1H6S 1;  2ZFG A;  3A0B O;  3HOL A;  3POQ A;  1MM4 A;  5PRN A;  3A2S X;  3UPG A;  3BS0 A;  3DA4 A;  5B5E O;  2Y7S A;  2Y0L A;  4N74 A;  4IL6 O;  4O3X B;  3PRN A;  5GTI O;  5AFU L;  4G75 A;  2X9K A;  3VE1 A;  4C4V B;  2ODJ A;  4GCP A;  5KAI O;  3AAE B;  3LK3 A;  3SZV A;  5GV0 A;  3BRZ A;  2XE1 A;  5DL5 A;  5G39 A;  3VZU X;  3AA1 B;  4AKM A;  3PGS A;  4C69 X;  2R4L A;  3BRY A;  2XTQ A;  1GFN A;  1BT9 A;  4AZL A;  2W80 C;  3JTY A;  2ERV A;  2R89 A;  1T16 A;  3T20 A;  2KZ7 A;  5E79 O;  4UB8 O;  3FYX A;  4RJW A;  3AA6 B;  4GCQ A;  4RJX A;  1ZHT A;  2WJR A;  2XTR A;  2ZLD A;  4D5U A;  3POU A;  2LHF A;  5T5F A;  3AA6 A;  3WU2 O;  4C4V A;  3AAE A;  3LK4 1;  2XE5 A;  1OSM A;  3AA0 B;  3LK3 B;  1ZHX A;  4FSO A;  2F1C X;  4FUV A; 
#chains in the Genus database with same CATH homology
 3UAQ A;  2K4T A;  3G7G A;  2YPV A;  1MPF A;  4O3Y A;  4RLC A;  2QTK A;  3AA7 A;  3PQS A;  4E1T A;  2FGQ X;  4O4U A;  3T0S A;  2Y0H A;  2J1N A;  1P4T A;  6PRN A;  5DL8 A;  3TZG A;  2N2L A;  4PUX A;  1E54 A;  4LSE A;  4KR8 A;  4D65 A;  2LFU A;  2Y0K A;  4D64 A;  5ADX L;  1HXT A;  1OPF A;  4AUI A;  2XMX A;  1YS5 A;  4AYD C;  4Z3T A;  7PRN A;  2PRN A;  1THQ A;  3SZD A;  2XE3 A;  4FRX A;  4GCS A;  4AYI D;  4GF4 A;  2O4V A;  4LSI A;  5EE2 A;  4AYN A;  4BUM X;  3DA3 A;  4U9C A;  3V8U A;  4KRA A;  4KR4 A;  3VY8 X;  3WI5 A;  4QQ1 A;  4N59 A;  3VZW X;  1IZN A;  1GFM A;  2GE4 A;  4FZM A;  4O3W A;  4O4X A;  1PRN A;  4E1S A;  2FGR A;  3PQU A;  2J4U P;  4N58 A;  4RLB A;  4O49 A;  1QJ9 A;  3C5O A;  8PRN A;  3AAA B;  2W81 C;  5JDP A;  3VY9 X;  2XE2 A;  1GFO A;  3HW9 A;  2XG6 A;  4AYM C;  4AYE C;  1PHO A;  3KVD D;  3VZT X;  4GHB A;  1QJP A;  1Q9F A;  4F4B A;  3EMN X;  5DL6 A;  1BH3 A;  4FES A;  2KXP A;  4FSP A;  3AA7 B;  1ZHY A;  1G90 A;  2K0L A;  3RBH A;  3SY9 A;  4AKR A;  4O3Z A;  3T24 A;  2KXP B;  2Y2X A;  5D5D A;  5ADX K;  3LK2 B;  4JCH A;  2POR A;  4FT6 A;  3HWB A;  3LK2 A;  3NSG A;  1QJ8 A;  5G26 A;  1BXW A;  1MM5 A;  3SY7 A;  1ZHW A;  3LK4 2;  4AKR B;  3AAA A;  2M07 A;  5AFU K;  2KDY A;  3K19 A;  1HXU A;  1GFQ A;  3AA0 A;  2X27 X;  1ZHZ A;  4FMS A;  3WI4 A;  2OMF A;  4FRT A;  4RL9 A;  4LSF A;  4XNK A;  4AFK A;  5FVN A;  2KZ7 B;  3QRC A;  2JMM A;  2N2M A;  3SYB A;  1HXX A;  3POX A;  3QRA A;  5DL7 A;  2F1V A;  4XNL A;  2MNH A;  4JFB A;  3VE2 A;  2MHL A;  3POR A;  2F1T A;  1GFP A;  1IZN B;  2KC0 A;  4FZL A;  5IYU A;  3GP6 A;  3AA1 A;  1Q9G A;  2M06 A;  1ORM A;  4B61 A;  3O0E A;  2YNK A;  3UU2 A;  4LSH A;  4G76 A;  4FOZ A;  3HOE A;  3SYS A;  4FZN A;  1H6S 1;  2ZFG A;  3HOL A;  3POQ A;  1MM4 A;  5PRN A;  3A2S X;  3UPG A;  3DA4 A;  2Y7S A;  2Y0L A;  4O3X B;  3PRN A;  5AFU L;  4G75 A;  3VE1 A;  2ODJ A;  4GCP A;  3SZV A;  3AAE B;  3LK3 A;  5GV0 A;  2XE1 A;  5DL5 A;  3VZU X;  4AKM A;  3AA1 B;  4C69 X;  2XTQ A;  1GFN A;  1BT9 A;  4AZL A;  2W80 C;  3JTY A;  2ERV A;  3T20 A;  2KZ7 A;  3FYX A;  4RJW A;  3AA6 B;  4GCQ A;  4RJX A;  1ZHT A;  2XTR A;  2ZLD A;  4D5U A;  3POU A;  2LHF A;  5T5F A;  3AA6 A;  3AAE A;  3LK4 1;  2XE5 A;  1OSM A;  3AA0 B;  3LK3 B;  1ZHX A;  4FSO A;  4FUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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