5JDPA

E73v mutant of the human voltage-dependent anion channel
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
285
structure length
285
Chain Sequence
SAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTVKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQARS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 56
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2016-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 5jdpA00
6PRNA 3O0EA 1GFOA 5DL5A 4AUIA 4D5UA 3SY9A 3POXA 3HWBA 7PRNA 2QTKA 2ZLDA 2XE5A 3VZUX 1GFNA 4GCQA 4KR4A 4FRTA 4FT6A 3A2SX 2OMFA 3POQA 1BH3A 2PRNA 8PRNA 3UPGA 3HW9A 3SY7A 1HXTA 3PRNA 1GFPA 3UU2A 1H6S1 2J1NA 2ZFGA 2XG6A 3VZWX 1HXUA 3K19A 3T0SA 2ODJA 4KRAA 2XE2A 2Y0LA 4D64A 3WI5A 1GFMA 2Y0KA 2PORA 4RJXA 4FSOA 4BUMX 1PHOA 2FGRA 4GCPA 5DL6A 4FSPA 5DL8A 4C69X 1OSMA 5FVNA 3NSGA 4FMSA 4LSHA 5DL7A 4LSIA 3POUA 4FOZA 3SYBA 3VY9X 4LSFA 4RJWA 3VY8X 3WI4A 3JTYA 2J4UP 4KR8A 3PORA 4GCSA 4LSEA 1OPFA 4JFBA 5JDPA 1E54A 2FGQX 2XE1A 3SZDA 3SYSA 4FRXA 1MPFA 1PRNA 4D65A 5PRNA 2O4VA 3FYXA 3VZTX 1GFQA 3EMNX 2Y0HA 3SZVA 1HXXA 1BT9A 2K4TA 3T24A 2Y2XA 3T20A 2XE3A
chains in the Genus database with same CATH superfamily
5KAFO 6PRNA 2IWWA 4B61A 4N59A 3O0EA 1GFOA 2R4PA 3AA0B 4JCHA 5DL5A 4FZNA 4AUIA 2XMXA 4UB8O 3AA7B 5E79O 4D5UA 2R8AA 3AAAA 3POXA 3SY9A 3BS0A 3DWOX 3HWBA 7PRNA 4O3ZA 4C4VB 2QTKA 3AA1A 2ZLDA 4G76A 4K3CA 2F1CX 3UAQA 4O3WA 2XE5A 3VZUX 5IYUA 1GFNA 2ERVA 3BRYA 4FRTA 4GCQA 2Y7SA 4FT6A 4KR4A 4AKRA 3A2SX 3AAEA 2KDYA 2JQYA 2OMFA 5GTHO 3POQA 3DWNA 3LK41 4GHBA 1BH3A 3V8UA 2PRNA 2XTRA 4O3XB 2R88A 4AZLA 5G26A 5AFUK 4AFKA 2R4LA 8PRNA 3UPGA 1G90A 1IZNA 2LHFA 3HW9A 3SY7A 1HXTA 2W80C 1MM4A 3C5OA 4IL6O 2YPVA 1T16A 2X9KA 5G38A 4O4UA 3PRNA 1GFPA 4E1TA 4AYMC 3UU2A 4PJ0O 1H6S1 4AYEC 2XTQA 2F1VA 2WJRA 3PF1A 5TISO 2J1NA 2N2MA 3AA6A 2ZFGA 2XG6A 3VZWX 5KAIO 4K3BA 3PGSA 4AKMA 5GV0A 2K0LA 1HXUA 3K19A 2MNHA 2WVPA 3T0SA 3LK2B 5GTIO 4G75A 3JCUO 3VE2A 2ODJA 3LK3B 4KRAA 2XE2A 2Y0LA 5B66O 3PGRA 4D64A 4QQ1A 4XNKA 3WI5A 1GFMA 2Y0KA 2PORA 4RJXA 4FESA 4FSOA 1ZHWA 4BUMX 2M07A 3GP6A 4PUXA 1ZHZA 3A0HO 1PHOA 2FGRA 4GCPA 3HOLA 2KZ7A 3PQSA 4CTDA 4O3YA 5B5EO 3PGUA 2R4NA 3KZIO 4GF4A 5DL6A 5EE2A 4FSPA 1ZHTA 3DA3A 1ZHXA 5DL8A 1MM5A 4C69X 1OSMA 5FVNA 3NSGA 4FMSA 3QRAA 4LSHA 4AYNA 3A0BO 1Q9FA 3AA1B 2M06A 1Q9GA 5DL7A 4LSIA 5T5FA 3POUA 2MHLA 4FOZA 3AA0A 3PQUA 3DA4A 3AAEB 3SYBA 4N74A 3VY9X 4RLCA 5D5DA 3AA7A 4LSFA 4RJWA 4FZLA 3VY8X 3WI4A 3JTYA 2KC0A 3HOEA 4KR8A 2J4UP 4Z3TA 3LK2A 2KXPB 3PORA 1ZHYA 2JMMA 2N2LA 4C4VA 4GCSA 4LSEA 1P4TA 3LK3A 1IZNB 3QRCA 3RBHA 1OPFA 2AXTO 3BRZA 1THQA 2R4OA 4XNLA 4O49A 4JFBA 5JDPA 3G7GA 1E54A 3TZGA 5ADXL 2FGQX 2XE1A 3AA6B 3KVDD 3SZDA 4PR7A 4C00A 4F4BA 2F1TA 3SYSA 3AAAB 4FRXA 1QJ9A 3DZMA 2LFUA 2IWVA 3WU2O 1MPFA 1T1LA 1PRNA 2X27X 4N75A 4RLBA 3VE1A 4E1SA 4N58A 4UB6O 5PRNA 4U9CA 4D65A 5G3AA 5H2FO 4AKRB 2W81C 5G39A 2O4VA 3FYXA 1S5LO 3VZTX 1GFQA 3EMNX 1QJ8A 2Y0HA 3LK42 2GE4A 3SZVA 4RL9A 1HXXA 1ORMA 2KZ7B 2R89A 3NJTA 1BT9A 4AYDC 2KXPA 2WJQA 2K4TA 3T24A 2Y2XA 3T20A 4FQEA 1QJPA 4AYID 1YS5A 4O4XA 5ADXK 2YNKA 4FUVA 5AFUL 4FZMA 2XE3A 1BXWA
chains in the Genus database with same CATH topology
6PRNA 4B61A 4N59A 3O0EA 1GFOA 4JCHA 3AA0B 5DL5A 4FZNA 4AUIA 2XMXA 3AA7B 4D5UA 3SY9A 3AAAA 3POXA 3HWBA 7PRNA 4O3ZA 2QTKA 3AA1A 2ZLDA 4G76A 3UAQA 4O3WA 2XE5A 3VZUX 5IYUA 1GFNA 2ERVA 4GCQA 4FRTA 4KR4A 2Y7SA 4FT6A 4AKRA 3A2SX 3AAEA 2KDYA 2OMFA 3POQA 3LK41 4GHBA 1BH3A 3V8UA 2PRNA 2XTRA 4O3XB 5G26A 5AFUK 4AFKA 8PRNA 3UPGA 1G90A 1IZNA 2LHFA 3HW9A 3SY7A 1HXTA 2W80C 1MM4A 3C5OA 4AZLA 2YPVA 4O4UA 3PRNA 1GFPA 4E1TA 4AYMC 3UU2A 1H6S1 4AYEC 2XTQA 2F1VA 2J1NA 2N2MA 3AA6A 2ZFGA 2XG6A 3VZWX 4AKMA 5GV0A 2K0LA 1HXUA 3K19A 2MNHA 3T0SA 3LK2B 4G75A 3VE2A 2ODJA 3LK3B 4KRAA 2XE2A 2Y0LA 4D64A 4QQ1A 4XNKA 3WI5A 1GFMA 2Y0KA 2PORA 4RJXA 4FESA 4FSOA 1ZHWA 4BUMX 2M07A 3GP6A 4PUXA 1ZHZA 1PHOA 2FGRA 4GCPA 3HOLA 2KZ7A 3PQSA 4O3YA 4GF4A 5DL6A 5EE2A 4FSPA 1ZHTA 3DA3A 1ZHXA 5DL8A 1MM5A 4C69X 1OSMA 5FVNA 3NSGA 4FMSA 3QRAA 4LSHA 4AYNA 1Q9FA 3AA1B 2M06A 1Q9GA 5DL7A 4LSIA 5T5FA 3POUA 2MHLA 4FOZA 3AA0A 3PQUA 3DA4A 3AAEB 3SYBA 3VY9X 4RLCA 5D5DA 3AA7A 4LSFA 4RJWA 4FZLA 3VY8X 3WI4A 3JTYA 2KC0A 3HOEA 4KR8A 2J4UP 4Z3TA 3LK2A 2KXPB 3PORA 1ZHYA 2JMMA 2N2LA 4GCSA 4LSEA 1P4TA 3LK3A 1IZNB 3QRCA 3RBHA 1OPFA 1THQA 4XNLA 4O49A 4JFBA 5JDPA 3G7GA 1E54A 3TZGA 5ADXL 2FGQX 2XE1A 3AA6B 3KVDD 3SZDA 4F4BA 2F1TA 3SYSA 3AAAB 4FRXA 1QJ9A 2LFUA 1MPFA 2X27X 1PRNA 4RLBA 3VE1A 4E1SA 4N58A 5PRNA 4D65A 4U9CA 4AKRB 2W81C 2O4VA 3FYXA 3VZTX 1GFQA 3EMNX 1QJ8A 2Y0HA 3LK42 2GE4A 3SZVA 4RL9A 1HXXA 1ORMA 2KZ7B 1BT9A 4AYDC 2KXPA 2K4TA 3T24A 2Y2XA 3T20A 4AYID 1QJPA 5ADXK 1YS5A 4O4XA 2YNKA 4FUVA 5AFUL 4FZMA 2XE3A 1BXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6PRN A;  3O0E A;  1GFO A;  5DL5 A;  4AUI A;  4D5U A;  3SY9 A;  3POX A;  3HWB A;  7PRN A;  2QTK A;  2ZLD A;  2XE5 A;  3VZU X;  1GFN A;  4GCQ A;  4KR4 A;  4FRT A;  4FT6 A;  3A2S X;  2OMF A;  3POQ A;  1BH3 A;  2PRN A;  8PRN A;  3UPG A;  3HW9 A;  3SY7 A;  1HXT A;  3PRN A;  1GFP A;  3UU2 A;  1H6S 1;  2J1N A;  2ZFG A;  2XG6 A;  3VZW X;  1HXU A;  3K19 A;  3T0S A;  2ODJ A;  4KRA A;  2XE2 A;  2Y0L A;  4D64 A;  3WI5 A;  1GFM A;  2Y0K A;  2POR A;  4RJX A;  4FSO A;  4BUM X;  1PHO A;  2FGR A;  4GCP A;  5DL6 A;  4FSP A;  5DL8 A;  4C69 X;  1OSM A;  5FVN A;  3NSG A;  4FMS A;  4LSH A;  5DL7 A;  4LSI A;  3POU A;  4FOZ A;  3SYB A;  3VY9 X;  4LSF A;  4RJW A;  3VY8 X;  3WI4 A;  3JTY A;  2J4U P;  4KR8 A;  3POR A;  4GCS A;  4LSE A;  1OPF A;  4JFB A;  5JDP A;  1E54 A;  2FGQ X;  2XE1 A;  3SZD A;  3SYS A;  4FRX A;  1MPF A;  1PRN A;  4D65 A;  5PRN A;  2O4V A;  3FYX A;  3VZT X;  1GFQ A;  3EMN X;  2Y0H A;  3SZV A;  1HXX A;  1BT9 A;  2K4T A;  3T24 A;  2Y2X A;  3T20 A;  2XE3 A; 
#chains in the Genus database with same CATH topology
 5KAF O;  6PRN A;  2IWW A;  4B61 A;  4N59 A;  3O0E A;  1GFO A;  2R4P A;  3AA0 B;  4JCH A;  5DL5 A;  4FZN A;  4AUI A;  2XMX A;  4UB8 O;  3AA7 B;  5E79 O;  4D5U A;  2R8A A;  3AAA A;  3POX A;  3SY9 A;  3BS0 A;  3DWO X;  3HWB A;  7PRN A;  4O3Z A;  4C4V B;  2QTK A;  3AA1 A;  2ZLD A;  4G76 A;  4K3C A;  2F1C X;  3UAQ A;  4O3W A;  2XE5 A;  3VZU X;  5IYU A;  1GFN A;  2ERV A;  3BRY A;  4FRT A;  4GCQ A;  2Y7S A;  4FT6 A;  4KR4 A;  4AKR A;  3A2S X;  3AAE A;  2KDY A;  2JQY A;  2OMF A;  5GTH O;  3POQ A;  3DWN A;  3LK4 1;  4GHB A;  1BH3 A;  3V8U A;  2PRN A;  2XTR A;  4O3X B;  2R88 A;  4AZL A;  5G26 A;  5AFU K;  4AFK A;  2R4L A;  8PRN A;  3UPG A;  1G90 A;  1IZN A;  2LHF A;  3HW9 A;  3SY7 A;  1HXT A;  2W80 C;  1MM4 A;  3C5O A;  4IL6 O;  2YPV A;  1T16 A;  2X9K A;  5G38 A;  4O4U A;  3PRN A;  1GFP A;  4E1T A;  4AYM C;  3UU2 A;  4PJ0 O;  1H6S 1;  4AYE C;  2XTQ A;  2F1V A;  2WJR A;  3PF1 A;  5TIS O;  2J1N A;  2N2M A;  3AA6 A;  2ZFG A;  2XG6 A;  3VZW X;  5KAI O;  4K3B A;  3PGS A;  4AKM A;  5GV0 A;  2K0L A;  1HXU A;  3K19 A;  2MNH A;  2WVP A;  3T0S A;  3LK2 B;  5GTI O;  4G75 A;  3JCU O;  3VE2 A;  2ODJ A;  3LK3 B;  4KRA A;  2XE2 A;  2Y0L A;  5B66 O;  3PGR A;  4D64 A;  4QQ1 A;  4XNK A;  3WI5 A;  1GFM A;  2Y0K A;  2POR A;  4RJX A;  4FES A;  4FSO A;  1ZHW A;  4BUM X;  2M07 A;  3GP6 A;  4PUX A;  1ZHZ A;  3A0H O;  1PHO A;  2FGR A;  4GCP A;  3HOL A;  2KZ7 A;  3PQS A;  4CTD A;  4O3Y A;  5B5E O;  3PGU A;  2R4N A;  3KZI O;  4GF4 A;  5DL6 A;  5EE2 A;  4FSP A;  1ZHT A;  3DA3 A;  1ZHX A;  5DL8 A;  1MM5 A;  4C69 X;  1OSM A;  5FVN A;  3NSG A;  4FMS A;  3QRA A;  4LSH A;  4AYN A;  3A0B O;  1Q9F A;  3AA1 B;  2M06 A;  1Q9G A;  5DL7 A;  4LSI A;  5T5F A;  3POU A;  2MHL A;  4FOZ A;  3AA0 A;  3PQU A;  3DA4 A;  3AAE B;  3SYB A;  4N74 A;  3VY9 X;  4RLC A;  5D5D A;  3AA7 A;  4LSF A;  4RJW A;  4FZL A;  3VY8 X;  3WI4 A;  3JTY A;  2KC0 A;  3HOE A;  4KR8 A;  2J4U P;  4Z3T A;  3LK2 A;  2KXP B;  3POR A;  1ZHY A;  2JMM A;  2N2L A;  4C4V A;  4GCS A;  4LSE A;  1P4T A;  3LK3 A;  1IZN B;  3QRC A;  3RBH A;  1OPF A;  2AXT O;  3BRZ A;  1THQ A;  2R4O A;  4XNL A;  4O49 A;  4JFB A;  5JDP A;  3G7G A;  1E54 A;  3TZG A;  5ADX L;  2FGQ X;  2XE1 A;  3AA6 B;  3KVD D;  3SZD A;  4PR7 A;  4C00 A;  4F4B A;  2F1T A;  3SYS A;  3AAA B;  4FRX A;  1QJ9 A;  3DZM A;  2LFU A;  2IWV A;  3WU2 O;  1MPF A;  1T1L A;  1PRN A;  2X27 X;  4N75 A;  4RLB A;  3VE1 A;  4E1S A;  4N58 A;  4UB6 O;  5PRN A;  4U9C A;  4D65 A;  5G3A A;  5H2F O;  4AKR B;  2W81 C;  5G39 A;  2O4V A;  3FYX A;  1S5L O;  3VZT X;  1GFQ A;  3EMN X;  1QJ8 A;  2Y0H A;  3LK4 2;  2GE4 A;  3SZV A;  4RL9 A;  1HXX A;  1ORM A;  2KZ7 B;  2R89 A;  3NJT A;  1BT9 A;  4AYD C;  2KXP A;  2WJQ A;  2K4T A;  3T24 A;  2Y2X A;  3T20 A;  4FQE A;  1QJP A;  4AYI D;  1YS5 A;  4O4X A;  5ADX K;  2YNK A;  4FUV A;  5AFU L;  4FZM A;  2XE3 A;  1BXW A; 
#chains in the Genus database with same CATH homology
 6PRN A;  4B61 A;  4N59 A;  3O0E A;  1GFO A;  4JCH A;  3AA0 B;  5DL5 A;  4FZN A;  4AUI A;  2XMX A;  3AA7 B;  4D5U A;  3SY9 A;  3AAA A;  3POX A;  3HWB A;  7PRN A;  4O3Z A;  2QTK A;  3AA1 A;  2ZLD A;  4G76 A;  3UAQ A;  4O3W A;  2XE5 A;  3VZU X;  5IYU A;  1GFN A;  2ERV A;  4GCQ A;  4FRT A;  4KR4 A;  2Y7S A;  4FT6 A;  4AKR A;  3A2S X;  3AAE A;  2KDY A;  2OMF A;  3POQ A;  3LK4 1;  4GHB A;  1BH3 A;  3V8U A;  2PRN A;  2XTR A;  4O3X B;  5G26 A;  5AFU K;  4AFK A;  8PRN A;  3UPG A;  1G90 A;  1IZN A;  2LHF A;  3HW9 A;  3SY7 A;  1HXT A;  2W80 C;  1MM4 A;  3C5O A;  4AZL A;  2YPV A;  4O4U A;  3PRN A;  1GFP A;  4E1T A;  4AYM C;  3UU2 A;  1H6S 1;  4AYE C;  2XTQ A;  2F1V A;  2J1N A;  2N2M A;  3AA6 A;  2ZFG A;  2XG6 A;  3VZW X;  4AKM A;  5GV0 A;  2K0L A;  1HXU A;  3K19 A;  2MNH A;  3T0S A;  3LK2 B;  4G75 A;  3VE2 A;  2ODJ A;  3LK3 B;  4KRA A;  2XE2 A;  2Y0L A;  4D64 A;  4QQ1 A;  4XNK A;  3WI5 A;  1GFM A;  2Y0K A;  2POR A;  4RJX A;  4FES A;  4FSO A;  1ZHW A;  4BUM X;  2M07 A;  3GP6 A;  4PUX A;  1ZHZ A;  1PHO A;  2FGR A;  4GCP A;  3HOL A;  2KZ7 A;  3PQS A;  4O3Y A;  4GF4 A;  5DL6 A;  5EE2 A;  4FSP A;  1ZHT A;  3DA3 A;  1ZHX A;  5DL8 A;  1MM5 A;  4C69 X;  1OSM A;  5FVN A;  3NSG A;  4FMS A;  3QRA A;  4LSH A;  4AYN A;  1Q9F A;  3AA1 B;  2M06 A;  1Q9G A;  5DL7 A;  4LSI A;  5T5F A;  3POU A;  2MHL A;  4FOZ A;  3AA0 A;  3PQU A;  3DA4 A;  3AAE B;  3SYB A;  3VY9 X;  4RLC A;  5D5D A;  3AA7 A;  4LSF A;  4RJW A;  4FZL A;  3VY8 X;  3WI4 A;  3JTY A;  2KC0 A;  3HOE A;  4KR8 A;  2J4U P;  4Z3T A;  3LK2 A;  2KXP B;  3POR A;  1ZHY A;  2JMM A;  2N2L A;  4GCS A;  4LSE A;  1P4T A;  3LK3 A;  1IZN B;  3QRC A;  3RBH A;  1OPF A;  1THQ A;  4XNL A;  4O49 A;  4JFB A;  5JDP A;  3G7G A;  1E54 A;  3TZG A;  5ADX L;  2FGQ X;  2XE1 A;  3AA6 B;  3KVD D;  3SZD A;  4F4B A;  2F1T A;  3SYS A;  3AAA B;  4FRX A;  1QJ9 A;  2LFU A;  1MPF A;  2X27 X;  1PRN A;  4RLB A;  3VE1 A;  4E1S A;  4N58 A;  5PRN A;  4D65 A;  4U9C A;  4AKR B;  2W81 C;  2O4V A;  3FYX A;  3VZT X;  1GFQ A;  3EMN X;  1QJ8 A;  2Y0H A;  3LK4 2;  2GE4 A;  3SZV A;  4RL9 A;  1HXX A;  1ORM A;  2KZ7 B;  1BT9 A;  4AYD C;  2KXP A;  2K4T A;  3T24 A;  2Y2X A;  3T20 A;  4AYI D;  1QJP A;  5ADX K;  1YS5 A;  4O4X A;  2YNK A;  4FUV A;  5AFU L;  4FZM A;  2XE3 A;  1BXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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