5JDPA

E73v mutant of the human voltage-dependent anion channel
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
285
structure length
285
Chain Sequence
SAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTVKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQARS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Membrane protein
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 56
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2016-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 5jdpA00
2ZFGA 3VZUX 3FYXA 2Y0LA 4D64A 3VZTX 1BH3A 2QTKA 2Y2XA 6PRNA 2Y0HA 5JDPA 3SYSA 1GFQA 3T20A 1H6S1 2J1NA 5FVNA 3WI4A 1HXTA 4FOZA 5DL8A 2XE2A 2PORA 3SYBA 1E54A 2XE3A 4AUIA 3SZDA 4FRTA 4GCPA 1GFOA 2PRNA 1BT9A 3WI5A 4KR4A 2ODJA 3HW9A 4KR8A 3T0SA 2XE5A 1PHOA 4D65A 4LSIA 8PRNA 3UPGA 4FMSA 1OPFA 5PRNA 3SZVA 1OSMA 4JFBA 2O4VA 4LSFA 4D5UA 4GCQA 3POQA 1GFPA 2OMFA 1HXUA 4LSEA 4FSOA 3VY9X 2XG6A 3HWBA 3NSGA 3A2SX 1MPFA 2Y0KA 5DL6A 3POUA 3POXA 4FT6A 3EMNX 4FRXA 5DL7A 5DL5A 3O0EA 3SY9A 3PORA 3K19A 4KRAA 4FSPA 3VY8X 3PRNA 3SY7A 3T24A 4RJWA 2ZLDA 7PRNA 2FGQX 3JTYA 3VZWX 2FGRA 3UU2A 4BUMX 4C69X 4GCSA 2J4UP 1GFNA 2XE1A 1HXXA 1PRNA 2K4TA 4LSHA 4RJXA 1GFMA
chains in the Genus database with same CATH superfamily
2W80C 2ZFGA 1ZHWA 3GP6A 4GHBA 4PUXA 3VZUX 3FYXA 4FUVA 5GV0A 2Y0LA 2KZ7A 2LHFA 3UAQA 1QJPA 5KAFO 2XMXA 3AAAB 2R8AA 3AA0B 4RL9A 4G76A 4D64A 3VZTX 1BH3A 2QTKA 2WJRA 2Y2XA 4C4VA 6PRNA 2Y0HA 2M07A 1Q9GA 4B61A 3BS0A 2N2LA 1MM5A 2KDYA 5G39A 5GTHO 5JDPA 2XTQA 2AXTO 1GFQA 2YPVA 3SYSA 5B66O 3T20A 1H6S1 5AFUL 1ZHYA 1IZNA 2LFUA 2J1NA 2F1VA 2R4LA 3HOEA 5FVNA 1HXTA 3WI4A 1QJ8A 3KVDD 3PF1A 1ZHXA 4FOZA 2XE2A 3AA1A 5DL8A 4O4XA 5G3AA 3LK3A 2PORA 3SYBA 1E54A 2XE3A 4AUIA 3SZDA 3AA6B 4QQ1A 4U9CA 3AA7B 4FRTA 4RJXA 3T0SA 4F4BA 4GCPA 1GFOA 4Z3TA 4O3YA 2PRNA 3DWNA 4FQEA 1G90A 2JMMA 1BT9A 1P4TA 4E1TA 5GTIO 4N75A 3WI5A 4KR4A 2ODJA 1Q9FA 2F1CX 3AA0A 3PGUA 3HW9A 3PGRA 4G75A 4KR8A 1MM4A 2JQYA 2F1TA 2XE5A 1PHOA 2R4PA 3AA6A 1BXWA 4K3BA 4LSIA 4UB6O 4D65A 4O49A 2KXPA 3LK2B 3A0HO 8PRNA 2R88A 5ADXL 4AKMA 3UPGA 1IZNB 1QJ9A 2YNKA 3PQSA 4FMSA 1OPFA 2GE4A 2K0LA 3LK41 5PRNA 3LK42 3SZVA 2KC0A 2WJQA 1OSMA 3BRYA 3KZIO 4GF4A 4JFBA 4O3ZA 5G38A 5AFUK 5IYUA 1ZHZA 3QRCA 2O4VA 4E1SA 4LSFA 4D5UA 4GCQA 3POQA 4O3XB 1GFPA 4PJ0O 2ERVA 2OMFA 1HXUA 4LSEA 1ORMA 3BRZA 2X9KA 3QRAA 4FSOA 4AFKA 3JCUO 5TISO 3VY9X 4FESA 2XG6A 4AZLA 1YS5A 3HWBA 3NSGA 4AYNA 2MNHA 3DWOX 1THQA 2W81C 3AA1B 1T16A 4FZLA 3A2SX 1MPFA 5D5DA 3AAEA 2Y0KA 5DL6A 5ADXK 2KXPB 3LK2A 2N2MA 3DZMA 3POXA 3POUA 4FT6A 4IL6O 3EMNX 4FRXA 4O3WA 4UB8O 5DL7A 3RBHA 4AYEC 1ZHTA 4XNKA 3VE2A 5B5EO 2IWWA 2WVPA 5DL5A 4AYDC 2R89A 3NJTA 3A0BO 3O0EA 4FZNA 4RLCA 4K3CA 3PORA 3SY9A 2XTRA 4RLBA 3K19A 4PR7A 3VE1A 3G7GA 4KRAA 4C00A 2X27X 4FSPA 4C4VB 4N59A 4N58A 4AKRB 4O4UA 3VY8X 3PRNA 2KZ7B 5H2FO 3SY7A 3T24A 4RJWA 2ZLDA 4FZMA 5KAIO 7PRNA 2FGQX 3DA3A 3PQUA 3TZGA 3JTYA 2M06A 4AYMC 4CTDA 4AYID 2Y7SA 2MHLA 3PGSA 3VZWX 5E79O 2FGRA 5EE2A 5G26A 3V8UA 2R4OA 3AAAA 3UU2A 4BUMX 4AKRA 3C5OA 3WU2O 4GCSA 3AA7A 4C69X 4N74A 5T5FA 3AAEB 1T1LA 3DA4A 1GFNA 2IWVA 3LK3B 3HOLA 4JCHA 2J4UP 4XNLA 2XE1A 1S5LO 1HXXA 1PRNA 2K4TA 4LSHA 2R4NA 1GFMA
chains in the Genus database with same CATH topology
2W80C 2ZFGA 1ZHWA 3GP6A 4GHBA 4PUXA 3VZUX 3FYXA 4FUVA 5GV0A 2Y0LA 2KZ7A 2LHFA 3UAQA 1QJPA 2XMXA 3AAAB 3AA0B 4RL9A 4G76A 4D64A 3VZTX 1BH3A 2QTKA 2Y2XA 6PRNA 2Y0HA 2M07A 1Q9GA 4B61A 2N2LA 1MM5A 2KDYA 5JDPA 2XTQA 2YPVA 1GFQA 3SYSA 3T20A 1H6S1 5AFUL 1ZHYA 1IZNA 2LFUA 2J1NA 2F1VA 5FVNA 3HOEA 3WI4A 1HXTA 1QJ8A 3KVDD 1ZHXA 4FOZA 2XE2A 3AA1A 5DL8A 4O4XA 3LK3A 2PORA 3SYBA 1E54A 2XE3A 4AUIA 3SZDA 3AA6B 4QQ1A 4U9CA 3AA7B 4FRTA 4GCPA 1GFOA 4Z3TA 4O3YA 2PRNA 1G90A 2JMMA 1BT9A 1P4TA 4E1TA 3WI5A 4KR4A 2ODJA 1Q9FA 3AA0A 3HW9A 4G75A 4KR8A 1MM4A 2XE5A 2F1TA 3AA6A 1PHOA 3T0SA 4D65A 1BXWA 4LSIA 4O49A 2KXPA 3LK2B 8PRNA 5ADXL 3UPGA 4AKMA 1IZNB 1QJ9A 2YNKA 3PQSA 4FMSA 1OPFA 2GE4A 2K0LA 3LK41 5PRNA 3LK42 3SZVA 2KC0A 4GF4A 1OSMA 4O3ZA 4JFBA 5AFUK 5IYUA 1ZHZA 3QRCA 2O4VA 4E1SA 4LSFA 4D5UA 4GCQA 3POQA 4O3XB 1GFPA 2ERVA 2OMFA 1HXUA 4LSEA 1ORMA 3QRAA 4FSOA 4AFKA 3VY9X 4FESA 2XG6A 4AZLA 1YS5A 3HWBA 3NSGA 4AYNA 2MNHA 1THQA 2W81C 3AA1B 4FZLA 3A2SX 1MPFA 5D5DA 3AAEA 2Y0KA 5DL6A 5ADXK 2KXPB 3LK2A 2N2MA 3POXA 3POUA 4O3WA 4FT6A 3V8UA 3EMNX 4FRXA 3RBHA 4F4BA 5DL7A 4AYEC 1ZHTA 4XNKA 3VE2A 4AYDC 5DL5A 3O0EA 4RLCA 4FZNA 3SY9A 3PORA 2XTRA 4RLBA 3K19A 3VE1A 3G7GA 4KRAA 2X27X 4FSPA 4N59A 4N58A 4AKRB 4O4UA 3VY8X 3PRNA 2KZ7B 3SY7A 3T24A 4RJWA 2ZLDA 4FZMA 7PRNA 2FGQX 3DA3A 3PQUA 3TZGA 3JTYA 2M06A 4AYMC 4AYID 2Y7SA 2MHLA 3VZWX 2FGRA 5EE2A 5G26A 3AAAA 3UU2A 4BUMX 4AKRA 3C5OA 4C69X 4GCSA 3AA7A 5T5FA 3AAEB 3DA4A 1GFNA 3LK3B 4JCHA 3HOLA 2J4UP 4XNLA 2XE1A 1HXXA 1PRNA 2K4TA 4LSHA 4RJXA 1GFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZFG A;  3VZU X;  3FYX A;  2Y0L A;  4D64 A;  3VZT X;  1BH3 A;  2QTK A;  2Y2X A;  6PRN A;  2Y0H A;  5JDP A;  3SYS A;  1GFQ A;  3T20 A;  1H6S 1;  2J1N A;  5FVN A;  3WI4 A;  1HXT A;  4FOZ A;  5DL8 A;  2XE2 A;  2POR A;  3SYB A;  1E54 A;  2XE3 A;  4AUI A;  3SZD A;  4FRT A;  4GCP A;  1GFO A;  2PRN A;  1BT9 A;  3WI5 A;  4KR4 A;  2ODJ A;  3HW9 A;  4KR8 A;  3T0S A;  2XE5 A;  1PHO A;  4D65 A;  4LSI A;  8PRN A;  3UPG A;  4FMS A;  1OPF A;  5PRN A;  3SZV A;  1OSM A;  4JFB A;  2O4V A;  4LSF A;  4D5U A;  4GCQ A;  3POQ A;  1GFP A;  2OMF A;  1HXU A;  4LSE A;  4FSO A;  3VY9 X;  2XG6 A;  3HWB A;  3NSG A;  3A2S X;  1MPF A;  2Y0K A;  5DL6 A;  3POU A;  3POX A;  4FT6 A;  3EMN X;  4FRX A;  5DL7 A;  5DL5 A;  3O0E A;  3SY9 A;  3POR A;  3K19 A;  4KRA A;  4FSP A;  3VY8 X;  3PRN A;  3SY7 A;  3T24 A;  4RJW A;  2ZLD A;  7PRN A;  2FGQ X;  3JTY A;  3VZW X;  2FGR A;  3UU2 A;  4BUM X;  4C69 X;  4GCS A;  2J4U P;  1GFN A;  2XE1 A;  1HXX A;  1PRN A;  2K4T A;  4LSH A;  4RJX A;  1GFM A; 
#chains in the Genus database with same CATH topology
 2W80 C;  2ZFG A;  1ZHW A;  3GP6 A;  4GHB A;  4PUX A;  3VZU X;  3FYX A;  4FUV A;  5GV0 A;  2Y0L A;  2KZ7 A;  2LHF A;  3UAQ A;  1QJP A;  5KAF O;  2XMX A;  3AAA B;  2R8A A;  3AA0 B;  4RL9 A;  4G76 A;  4D64 A;  3VZT X;  1BH3 A;  2QTK A;  2WJR A;  2Y2X A;  4C4V A;  6PRN A;  2Y0H A;  2M07 A;  1Q9G A;  4B61 A;  3BS0 A;  2N2L A;  1MM5 A;  2KDY A;  5G39 A;  5GTH O;  5JDP A;  2XTQ A;  2AXT O;  1GFQ A;  2YPV A;  3SYS A;  5B66 O;  3T20 A;  1H6S 1;  5AFU L;  1ZHY A;  1IZN A;  2LFU A;  2J1N A;  2F1V A;  2R4L A;  3HOE A;  5FVN A;  1HXT A;  3WI4 A;  1QJ8 A;  3KVD D;  3PF1 A;  1ZHX A;  4FOZ A;  2XE2 A;  3AA1 A;  5DL8 A;  4O4X A;  5G3A A;  3LK3 A;  2POR A;  3SYB A;  1E54 A;  2XE3 A;  4AUI A;  3SZD A;  3AA6 B;  4QQ1 A;  4U9C A;  3AA7 B;  4FRT A;  4RJX A;  3T0S A;  4F4B A;  4GCP A;  1GFO A;  4Z3T A;  4O3Y A;  2PRN A;  3DWN A;  4FQE A;  1G90 A;  2JMM A;  1BT9 A;  1P4T A;  4E1T A;  5GTI O;  4N75 A;  3WI5 A;  4KR4 A;  2ODJ A;  1Q9F A;  2F1C X;  3AA0 A;  3PGU A;  3HW9 A;  3PGR A;  4G75 A;  4KR8 A;  1MM4 A;  2JQY A;  2F1T A;  2XE5 A;  1PHO A;  2R4P A;  3AA6 A;  1BXW A;  4K3B A;  4LSI A;  4UB6 O;  4D65 A;  4O49 A;  2KXP A;  3LK2 B;  3A0H O;  8PRN A;  2R88 A;  5ADX L;  4AKM A;  3UPG A;  1IZN B;  1QJ9 A;  2YNK A;  3PQS A;  4FMS A;  1OPF A;  2GE4 A;  2K0L A;  3LK4 1;  5PRN A;  3LK4 2;  3SZV A;  2KC0 A;  2WJQ A;  1OSM A;  3BRY A;  3KZI O;  4GF4 A;  4JFB A;  4O3Z A;  5G38 A;  5AFU K;  5IYU A;  1ZHZ A;  3QRC A;  2O4V A;  4E1S A;  4LSF A;  4D5U A;  4GCQ A;  3POQ A;  4O3X B;  1GFP A;  4PJ0 O;  2ERV A;  2OMF A;  1HXU A;  4LSE A;  1ORM A;  3BRZ A;  2X9K A;  3QRA A;  4FSO A;  4AFK A;  3JCU O;  5TIS O;  3VY9 X;  4FES A;  2XG6 A;  4AZL A;  1YS5 A;  3HWB A;  3NSG A;  4AYN A;  2MNH A;  3DWO X;  1THQ A;  2W81 C;  3AA1 B;  1T16 A;  4FZL A;  3A2S X;  1MPF A;  5D5D A;  3AAE A;  2Y0K A;  5DL6 A;  5ADX K;  2KXP B;  3LK2 A;  2N2M A;  3DZM A;  3POX A;  3POU A;  4FT6 A;  4IL6 O;  3EMN X;  4FRX A;  4O3W A;  4UB8 O;  5DL7 A;  3RBH A;  4AYE C;  1ZHT A;  4XNK A;  3VE2 A;  5B5E O;  2IWW A;  2WVP A;  5DL5 A;  4AYD C;  2R89 A;  3NJT A;  3A0B O;  3O0E A;  4FZN A;  4RLC A;  4K3C A;  3POR A;  3SY9 A;  2XTR A;  4RLB A;  3K19 A;  4PR7 A;  3VE1 A;  3G7G A;  4KRA A;  4C00 A;  2X27 X;  4FSP A;  4C4V B;  4N59 A;  4N58 A;  4AKR B;  4O4U A;  3VY8 X;  3PRN A;  2KZ7 B;  5H2F O;  3SY7 A;  3T24 A;  4RJW A;  2ZLD A;  4FZM A;  5KAI O;  7PRN A;  2FGQ X;  3DA3 A;  3PQU A;  3TZG A;  3JTY A;  2M06 A;  4AYM C;  4CTD A;  4AYI D;  2Y7S A;  2MHL A;  3PGS A;  3VZW X;  5E79 O;  2FGR A;  5EE2 A;  5G26 A;  3V8U A;  2R4O A;  3AAA A;  3UU2 A;  4BUM X;  4AKR A;  3C5O A;  3WU2 O;  4GCS A;  3AA7 A;  4C69 X;  4N74 A;  5T5F A;  3AAE B;  1T1L A;  3DA4 A;  1GFN A;  2IWV A;  3LK3 B;  3HOL A;  4JCH A;  2J4U P;  4XNL A;  2XE1 A;  1S5L O;  1HXX A;  1PRN A;  2K4T A;  4LSH A;  2R4N A;  1GFM A; 
#chains in the Genus database with same CATH homology
 2W80 C;  2ZFG A;  1ZHW A;  3GP6 A;  4GHB A;  4PUX A;  3VZU X;  3FYX A;  4FUV A;  5GV0 A;  2Y0L A;  2KZ7 A;  2LHF A;  3UAQ A;  1QJP A;  2XMX A;  3AAA B;  3AA0 B;  4RL9 A;  4G76 A;  4D64 A;  3VZT X;  1BH3 A;  2QTK A;  2Y2X A;  6PRN A;  2Y0H A;  2M07 A;  1Q9G A;  4B61 A;  2N2L A;  1MM5 A;  2KDY A;  5JDP A;  2XTQ A;  2YPV A;  1GFQ A;  3SYS A;  3T20 A;  1H6S 1;  5AFU L;  1ZHY A;  1IZN A;  2LFU A;  2J1N A;  2F1V A;  5FVN A;  3HOE A;  3WI4 A;  1HXT A;  1QJ8 A;  3KVD D;  1ZHX A;  4FOZ A;  2XE2 A;  3AA1 A;  5DL8 A;  4O4X A;  3LK3 A;  2POR A;  3SYB A;  1E54 A;  2XE3 A;  4AUI A;  3SZD A;  3AA6 B;  4QQ1 A;  4U9C A;  3AA7 B;  4FRT A;  4GCP A;  1GFO A;  4Z3T A;  4O3Y A;  2PRN A;  1G90 A;  2JMM A;  1BT9 A;  1P4T A;  4E1T A;  3WI5 A;  4KR4 A;  2ODJ A;  1Q9F A;  3AA0 A;  3HW9 A;  4G75 A;  4KR8 A;  1MM4 A;  2XE5 A;  2F1T A;  3AA6 A;  1PHO A;  3T0S A;  4D65 A;  1BXW A;  4LSI A;  4O49 A;  2KXP A;  3LK2 B;  8PRN A;  5ADX L;  3UPG A;  4AKM A;  1IZN B;  1QJ9 A;  2YNK A;  3PQS A;  4FMS A;  1OPF A;  2GE4 A;  2K0L A;  3LK4 1;  5PRN A;  3LK4 2;  3SZV A;  2KC0 A;  4GF4 A;  1OSM A;  4O3Z A;  4JFB A;  5AFU K;  5IYU A;  1ZHZ A;  3QRC A;  2O4V A;  4E1S A;  4LSF A;  4D5U A;  4GCQ A;  3POQ A;  4O3X B;  1GFP A;  2ERV A;  2OMF A;  1HXU A;  4LSE A;  1ORM A;  3QRA A;  4FSO A;  4AFK A;  3VY9 X;  4FES A;  2XG6 A;  4AZL A;  1YS5 A;  3HWB A;  3NSG A;  4AYN A;  2MNH A;  1THQ A;  2W81 C;  3AA1 B;  4FZL A;  3A2S X;  1MPF A;  5D5D A;  3AAE A;  2Y0K A;  5DL6 A;  5ADX K;  2KXP B;  3LK2 A;  2N2M A;  3POX A;  3POU A;  4O3W A;  4FT6 A;  3V8U A;  3EMN X;  4FRX A;  3RBH A;  4F4B A;  5DL7 A;  4AYE C;  1ZHT A;  4XNK A;  3VE2 A;  4AYD C;  5DL5 A;  3O0E A;  4RLC A;  4FZN A;  3SY9 A;  3POR A;  2XTR A;  4RLB A;  3K19 A;  3VE1 A;  3G7G A;  4KRA A;  2X27 X;  4FSP A;  4N59 A;  4N58 A;  4AKR B;  4O4U A;  3VY8 X;  3PRN A;  2KZ7 B;  3SY7 A;  3T24 A;  4RJW A;  2ZLD A;  4FZM A;  7PRN A;  2FGQ X;  3DA3 A;  3PQU A;  3TZG A;  3JTY A;  2M06 A;  4AYM C;  4AYI D;  2Y7S A;  2MHL A;  3VZW X;  2FGR A;  5EE2 A;  5G26 A;  3AAA A;  3UU2 A;  4BUM X;  4AKR A;  3C5O A;  4C69 X;  4GCS A;  3AA7 A;  5T5F A;  3AAE B;  3DA4 A;  1GFN A;  3LK3 B;  4JCH A;  3HOL A;  2J4U P;  4XNL A;  2XE1 A;  1HXX A;  1PRN A;  2K4T A;  4LSH A;  4RJX A;  1GFM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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