5JMYA

Neprilysin complexed with lbq657
Total Genus 275
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
696
structure length
696
Chain Sequence
GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Neprilysin
publication title Structure of neprilysin in complex with the active metabolite of sacubitril.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 275
structure length 696
sequence length 696
chains with identical sequence B
ec nomenclature ec 3.4.24.11: Neprilysin.
pdb deposition date 2016-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01431 Peptidase_M13 Peptidase family M13
A PF05649 Peptidase_M13_N Peptidase family M13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1380.10 Mainly Alpha Orthogonal Bundle Neutral endopeptidase; domain 2 Neutral endopeptidase , domain2 5jmyA02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5jmyA01
1WNIA 1BKCA 2DW0A 2OZRA 2JNPA 1EAKA 1QUAA 1JIZA 3K7LA 2DW1A 1Q3AA 4FVLA 1BQQM 3Q2HA 4DF9A 3LJZA 2OW9A 4J4MA 1XFUA 3B92A 5CUHA 1GE7A 3ZVSA 1IADA 1D8FA 830CA 2FV5A 1XUDA 3KMCA 1UTTA 3N2VA 3P1VA 1EB6A 4ILWD 4GR0A 3DL1A 2N8RA 5I12A 3DPEA 4I03A 1DTHA 2W15A 4PKSA 1GO7P 3B2ZA 2SRTA 3LEAA 1Y8JA 3UVCA 4H30A 1JAQA 4FXYP 1ZTQA 5JMYA 4PKTA 5BOYA 2OI0A 1JJ9A 1G9KA 1KBCA 3KHIA 1BM6A 3ZUKA 4Q1LA 2W12A 1CK7A 4L19A 3TVCA 1SU3A 4PKVA 3HY7A 2RJPA 3Q2GA 1K7GA 2X3AA 5I0LA 4A3WA 4DV8A 4I35A 2L0RA 1O0QA 3B8ZA 3LIKA 1Y0VA 3EHXA 2DDYA 2K9CA 1IACA 1R55A 4JPAA 4HMAA 2DDFA 4JQGA 4ZR5A 3O2XA 4AXQA 4GWNA 3LUNA 2ERPA 4GUYA 1D8MA 1B3DA 3LK8A 5D1SA 4GWMA 1QIBA 1SRPA 1ZXCA 2WOAA 1G49A 3KEJA 1YP1A 1CGFA 1JH1A 1Y93A 3VTGA 1UTZA 1K7IA 1HFCA 4WKIA 3L0TA 1MMQA 3OHOA 3F17A 1IABA 4ON1A 3TSKA 3DPFA 4IJOA 1BIWA 1OO9A 1XFZA 2X3BA 1GO8P 3G42A 5B5PA 1QJJA 1KUKA 3AYKA 4H49A 2OY2A 1OM6A 3V96B 1G05A 2RJQA 4GF1A 2W14A 1KUIA 1RM8A 4H76A 1G12A 1BUVM 5D1UA 2YIGA 3WV2A 5I43A 1I1IP 1ASTA 1JAOA 1OM8A 4L63A 3F16A 3NX7A 3LJTA 1H71P 2WO8A 4FU4A 2EROA 1R54A 3RTSA 1Z3JA 1XFXA 1GKCA 3EHYA 3LGPA 5D2BA 1AYKA 1MMRA 4AYKA 3HDAP 2MZEA 3LQ0A 3DSLA 2WO9A 1BSWA 3ZXHA 1EUBA 3GBOA 1A86A 1PWQA 3EDZA 2K2GA 1SLNA 3DWBA 3E8RA 4A7BA 3LMCA 3EWJA 1YQYA 1OMJA 1R1IA 1C7KA 3F19A 4CTHA 1UEAA 2OVZA 4IN9A 5BOTA 1XFWA 5I2ZA 1G4KA 2Y6CA 2J0TA 4G9LA 2YB9A 4R3VA 1FLSA 1FBLA 1PWUA 2W13A 1I73A 2HU6A 2USNA 2FV9A 1CIZA 3I7GA 3KMEA 4XM6A 1MMBA 1C8TA 3WV3A 3AIGA 1MNCA 4XM7A 4WZVA 3ELMA 1ND1A 1K7QA 4XBHA 2QPJA 1GE6A 1AKLA 5BPAA 3U1RA 4AIGA 4GQLA 1GE5A 4H3XA 2OXZA 5I3MA 4H2EA 4JP4A 1XURA 2V4BA 4PKUA 3G5CA 1ZP5A 3HBVP 5I4OA 1C3IA 4WKEA 1HTDA 1CAQA 2Y6DA 2O36A 1AF0A 4DD8A 4G0DA 4GR3A 2O3EA 1XUCA 3LE9A 1IAAA 3KRYA 1KUFA 2DW2A 1YOUA 2MLRA 3O64A 4PKWA 4H84A 1JIWP 3HYGA 2OW1A 3LJGA 3LIRA 1L6JA 1PWVA 3TS4A 5B5OA 5L79A 3WV1A 1GXDA 5LABA 2OVXA 4QKZA 4HX3A 966CA 3F18A 3HDBA 2W0DA 2JT6A 2J83A 5CXAA 3OHLA 2ERQA 1IAGA 1QJIA 4PKQA 2D1NA 1BKCI 1JK3A 3LUMA 3F15A 1CGEA 2MLSA 3KEKA 2A8HA 1B8YA 4XM8A 4IUWA 1O0TA 1USNA 1JAPA 3EDIA 1BKCE 456CA 2CLTA 4XCTA 3HBUP 2XS3A 4GR8A 2AYKA 1BZSA 1DMTA 4WF6A 4DPEA 2E2DA 3USNA 1HV5A 3AYUA 2OXWA 2AIGP 3DNGA 2CKIA 3P24A 3K7NA 2OW2A 1BQOA 3HB2P 2JT5A 1JANA 3BA0A 1IAEA 3KECA 5D7WA 1YCMA 1HOVA 3RTTA 2OY4A 3TT4A 2JIHA 2PJTA 3MA2A 3LQBA 1HFSA 2X7MA 1ZXVA 3N2UA 1PWPA 2XS4A 1R1JA 1ROSA 3HY9A 1ZVXA 1J7NA 1KUGA 1UMTA 4EFSA 3CKIA 4AUOA 1CGLA 1CQRA 1SLMA 1OS2A 3LILA 2TCLA 1UMSA 4PKRA 1JKYA 4H82A 1PWWA 4JIJA 1S4BP 2OW0A 3I7IA 1CXVA 3F1AA 1OM7A 1QIAA 2I47A 3EDHA 2KRJA 1MMPA 1SMPA 3EDGA 3SHIA 2JSDA 1QICA 2X3CA 2Z2DA 3VI1A 2E3XA 1RMZA 2OXUA 1KAPP 1SATA 2D1OA 1I76A 3KWVC 1ATLA 4L6TA 4H1QA 1KUHA 1OS9A 1GKDA 5D3CA 4WK7A 5D1TA 5H8XA 1R1HA 1XFYA 5CZMA 2MZIA 1FM1A 1D7XA 1BUDA 1ZS0A 3L0VA 1A85A 1XFVA 1HY7A 1D5JA 3LKAA 5L7FA 4FXQA 4JA1A 2POJA 2MZHA
chains in the Genus database with same CATH superfamily
1WNIA 1BKCA 2DW0A 2OZRA 2JNPA 1EAKA 1QUAA 1JIZA 3K7LA 2DW1A 1Q3AA 4FVLA 3DTEA 1BQQM 3Q2HA 4DF9A 3LJZA 2OW9A 4J4MA 1XFUA 3B92A 5CUHA 1GE7A 3ZVSA 1IADA 1D8FA 830CA 2FV5A 1XUDA 3KMCA 1UTTA 3N2VA 3P1VA 1EB6A 4ILWD 4GR0A 3DL1A 1XAXA 2N8RA 5I12A 3DPEA 4I03A 1DTHA 2W15A 4PKSA 1GO7P 3B2ZA 2SRTA 3LEAA 1Y8JA 3UVCA 4H30A 1JAQA 4FXYP 1ZTQA 5JMYA 4PKTA 5BOYA 3DTIA 2OI0A 1JJ9A 1G9KA 1KBCA 3KHIA 1BM6A 3ZUKA 4Q1LA 2W12A 1CK7A 4L19A 3TVCA 1SU3A 4PKVA 3HY7A 2RJPA 3Q2GA 1K7GA 2X3AA 5I0LA 2YUFA 4A3WA 4DV8A 4I35A 2L0RA 1O0QA 3B8ZA 3LIKA 1Y0VA 3EHXA 2DDYA 2K9CA 1IACA 1R55A 4JPAA 4HMAA 2DDFA 4JQGA 4ZR5A 3O2XA 4AXQA 4GWNA 3LUNA 2ERPA 4GUYA 1D8MA 1B3DA 3LK8A 5D1SA 4GWMA 1QIBA 1SRPA 1ZXCA 2WOAA 1G49A 3KEJA 1YP1A 1CGFA 1JH1A 1Y93A 3VTGA 1UTZA 1K7IA 1HFCA 4WKIA 3L0TA 1MMQA 3OHOA 3F17A 1IABA 4ON1A 3TSKA 3DPFA 4IJOA 1BIWA 1OO9A 1XFZA 2X3BA 1GO8P 3G42A 5B5PA 1QJJA 1KUKA 3AYKA 4H49A 2OY2A 3DTKA 1OM6A 3V96B 1G05A 2RJQA 4GF1A 2W14A 1KUIA 1RM8A 4H76A 1G12A 1BUVM 5D1UA 2YIGA 3WV2A 5I43A 1I1IP 1ASTA 1JAOA 1OM8A 4L63A 3F16A 3NX7A 3LJTA 1H71P 2WO8A 4FU4A 2EROA 1R54A 3RTSA 1Z3JA 1XFXA 1GKCA 3EHYA 3LGPA 5D2BA 1AYKA 1MMRA 4AYKA 3HDAP 2MZEA 3LQ0A 3DSLA 2WO9A 1BSWA 3ZXHA 1EUBA 3GBOA 1A86A 1PWQA 3EDZA 2K2GA 1SLNA 3DWBA 3E8RA 4A7BA 3LMCA 3EWJA 1YQYA 1OMJA 1R1IA 1C7KA 3F19A 4CTHA 1UEAA 2OVZA 4IN9A 5BOTA 1XFWA 5I2ZA 1G4KA 2Y6CA 2J0TA 4G9LA 2YB9A 4R3VA 1FLSA 1FBLA 1PWUA 2W13A 1I73A 2HU6A 2USNA 2FV9A 1CIZA 3I7GA 3KMEA 4XM6A 1MMBA 1C8TA 3WV3A 3AIGA 1MNCA 4XM7A 4WZVA 3ELMA 1ND1A 1K7QA 4XBHA 2QPJA 1GE6A 1AKLA 5BPAA 3U1RA 4AIGA 4GQLA 1GE5A 4H3XA 2OXZA 5I3MA 4H2EA 4JP4A 1XURA 2V4BA 4PKUA 3G5CA 1ZP5A 3HBVP 5I4OA 1C3IA 4WKEA 1HTDA 1CAQA 2Y6DA 2O36A 1AF0A 4DD8A 4G0DA 4GR3A 2O3EA 1XUCA 3LE9A 1IAAA 3KRYA 1KUFA 2DW2A 1YOUA 1XM5A 2MLRA 3O64A 4PKWA 4H84A 1JIWP 3HYGA 2OW1A 3LJGA 3LIRA 1L6JA 1PWVA 3TS4A 5B5OA 5L79A 3WV1A 1GXDA 5LABA 2OVXA 4QKZA 4HX3A 966CA 3F18A 3HDBA 2W0DA 2JT6A 2J83A 5CXAA 3OHLA 2ERQA 1IAGA 1QJIA 4L7AA 4PKQA 2D1NA 1BKCI 1JK3A 3LUMA 3F15A 1CGEA 2MLSA 3KEKA 2A8HA 1B8YA 4XM8A 4IUWA 1O0TA 1USNA 1JAPA 3EDIA 1BKCE 456CA 2CLTA 4XCTA 3HBUP 2XS3A 4GR8A 2AYKA 1BZSA 1DMTA 4WF6A 4DPEA 2E2DA 3USNA 1HV5A 3AYUA 1TVIA 2OXWA 2AIGP 3DNGA 2CKIA 3P24A 3K7NA 2OW2A 1BQOA 3HB2P 2JT5A 1JANA 3BA0A 1IAEA 3KECA 5D7WA 1YCMA 1HOVA 3RTTA 2OY4A 3TT4A 2JIHA 2PJTA 3MA2A 3LQBA 1HFSA 2X7MA 1ZXVA 3N2UA 1PWPA 2XS4A 1R1JA 1ROSA 3HY9A 1ZVXA 1J7NA 1KUGA 1UMTA 4EFSA 3CKIA 4AUOA 1CGLA 1CQRA 1SLMA 1OS2A 3LILA 2TCLA 1UMSA 4PKRA 1JKYA 4H82A 1PWWA 4JIJA 1S4BP 2OW0A 3I7IA 1CXVA 3F1AA 1OM7A 1QIAA 2I47A 3EDHA 2KRJA 1MMPA 1SMPA 3EDGA 3SHIA 2JSDA 1QICA 2X3CA 2Z2DA 3VI1A 2E3XA 1RMZA 2OXUA 1KAPP 1SATA 2D1OA 1I76A 3KWVC 1ATLA 4L6TA 1OZ9A 4H1QA 1KUHA 1OS9A 1GKDA 5D3CA 4WK7A 5D1TA 5H8XA 1R1HA 1XFYA 5CZMA 2MZIA 1FM1A 1D7XA 1BUDA 1ZS0A 3L0VA 1A85A 1XFVA 1HY7A 1D5JA 3LKAA 5L7FA 4FXQA 4JA1A 2POJA 2MZHA
chains in the Genus database with same CATH topology
1WNIA 1BKCA 2DW0A 2OZRA 2JNPA 1EAKA 1QUAA 1JIZA 3K7LA 2DW1A 1Q3AA 4FVLA 3DTEA 1BQQM 3Q2HA 4DF9A 3LJZA 2OW9A 4J4MA 1XFUA 3B92A 5CUHA 1GE7A 3ZVSA 1IADA 1D8FA 830CA 2FV5A 1XUDA 3KMCA 1UTTA 3N2VA 3P1VA 1EB6A 4ILWD 4GR0A 3DL1A 2N8RA 5I12A 3DPEA 4I03A 1DTHA 2W15A 4PKSA 1GO7P 3B2ZA 2SRTA 3LEAA 1Y8JA 3UVCA 4H30A 1JAQA 4FXYP 1ZTQA 5JMYA 4PKTA 5BOYA 3DTIA 2OI0A 1JJ9A 1G9KA 1KBCA 3KHIA 1BM6A 3ZUKA 4Q1LA 2W12A 1CK7A 4L19A 3TVCA 1SU3A 4PKVA 3HY7A 2RJPA 3Q2GA 1K7GA 2X3AA 5I0LA 2YUFA 4A3WA 4DV8A 4I35A 2L0RA 1O0QA 3B8ZA 3LIKA 1Y0VA 3EHXA 2DDYA 2K9CA 1IACA 1R55A 4JPAA 4HMAA 2DDFA 4JQGA 4ZR5A 3O2XA 4AXQA 4GWNA 3LUNA 2ERPA 4GUYA 1D8MA 1B3DA 3LK8A 5D1SA 4GWMA 1QIBA 1SRPA 1ZXCA 2WOAA 1G49A 3KEJA 1YP1A 1CGFA 1JH1A 1Y93A 3VTGA 1UTZA 1K7IA 1HFCA 4WKIA 3L0TA 1MMQA 3OHOA 3F17A 1IABA 4ON1A 3TSKA 3DPFA 4IJOA 1BIWA 1OO9A 1XFZA 2X3BA 1GO8P 3G42A 5B5PA 1QJJA 1KUKA 3AYKA 4H49A 2OY2A 3DTKA 1OM6A 3V96B 1G05A 2RJQA 4GF1A 2W14A 1KUIA 1RM8A 4H76A 1G12A 1BUVM 5D1UA 2YIGA 3WV2A 5I43A 1I1IP 1ASTA 1JAOA 1OM8A 4L63A 3F16A 3NX7A 3LJTA 1H71P 2WO8A 4FU4A 2EROA 1R54A 3RTSA 1Z3JA 1XFXA 1GKCA 3EHYA 3LGPA 5D2BA 1AYKA 1MMRA 4AYKA 3HDAP 2MZEA 3LQ0A 3DSLA 2WO9A 1BSWA 3ZXHA 1EUBA 3GBOA 1A86A 1PWQA 3EDZA 2K2GA 1SLNA 3DWBA 3E8RA 4A7BA 3LMCA 3EWJA 1YQYA 1OMJA 1R1IA 1C7KA 3F19A 4CTHA 1UEAA 2OVZA 4IN9A 5BOTA 1XFWA 5I2ZA 1G4KA 2Y6CA 2J0TA 4G9LA 2YB9A 4R3VA 1FLSA 1FBLA 1PWUA 2W13A 1I73A 2HU6A 2USNA 2FV9A 1CIZA 3I7GA 3KMEA 4XM6A 1MMBA 1C8TA 3WV3A 3AIGA 1MNCA 4XM7A 4WZVA 3ELMA 1ND1A 1K7QA 4XBHA 2QPJA 1GE6A 1AKLA 5BPAA 3U1RA 4AIGA 4GQLA 1GE5A 4H3XA 2OXZA 5I3MA 4H2EA 4JP4A 1XURA 2V4BA 4PKUA 3G5CA 1ZP5A 3HBVP 5I4OA 1C3IA 4WKEA 1HTDA 1CAQA 2Y6DA 2O36A 1AF0A 4DD8A 4G0DA 4GR3A 2O3EA 1XUCA 3LE9A 1IAAA 3KRYA 1KUFA 2DW2A 1YOUA 2MLRA 3O64A 4PKWA 4H84A 1JIWP 3HYGA 2OW1A 3LJGA 3LIRA 1L6JA 1PWVA 3TS4A 5B5OA 5L79A 3WV1A 1GXDA 5LABA 2OVXA 4QKZA 4HX3A 966CA 3F18A 3HDBA 2W0DA 2JT6A 2J83A 5CXAA 3OHLA 2ERQA 1IAGA 1QJIA 4L7AA 4PKQA 2D1NA 1BKCI 1JK3A 3LUMA 3F15A 1CGEA 2MLSA 3KEKA 2A8HA 1B8YA 4XM8A 4IUWA 1O0TA 1USNA 1JAPA 3EDIA 1BKCE 456CA 2CLTA 4XCTA 3HBUP 2XS3A 4GR8A 2AYKA 1BZSA 1DMTA 4WF6A 4DPEA 2E2DA 3USNA 1HV5A 3AYUA 2OXWA 2AIGP 3DNGA 2CKIA 3P24A 3K7NA 2OW2A 1BQOA 3HB2P 2JT5A 1JANA 3BA0A 1IAEA 3KECA 5D7WA 1YCMA 1HOVA 3RTTA 2OY4A 3TT4A 2JIHA 2PJTA 3MA2A 3LQBA 1HFSA 2X7MA 1ZXVA 3N2UA 1PWPA 2XS4A 1R1JA 1ROSA 3HY9A 1ZVXA 1J7NA 1KUGA 1UMTA 4EFSA 3CKIA 4AUOA 1CGLA 1CQRA 1SLMA 1OS2A 3LILA 2TCLA 1UMSA 4PKRA 1JKYA 4H82A 1PWWA 4JIJA 1S4BP 2OW0A 3I7IA 1CXVA 3F1AA 1OM7A 1QIAA 2I47A 3EDHA 2KRJA 1MMPA 1SMPA 3EDGA 3SHIA 2JSDA 1QICA 2X3CA 2Z2DA 3VI1A 2E3XA 1RMZA 2OXUA 1KAPP 1SATA 2D1OA 1I76A 3KWVC 1ATLA 4L6TA 4H1QA 1KUHA 1OS9A 1GKDA 5D3CA 4WK7A 5D1TA 5H8XA 1R1HA 1XFYA 5CZMA 2MZIA 1FM1A 1D7XA 1BUDA 1ZS0A 3L0VA 1A85A 1XFVA 1HY7A 1D5JA 3LKAA 5L7FA 4FXQA 4JA1A 2POJA 2MZHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WNI A;  1BKC A;  2DW0 A;  2OZR A;  2JNP A;  1EAK A;  1QUA A;  1JIZ A;  3K7L A;  2DW1 A;  1Q3A A;  4FVL A;  1BQQ M;  3Q2H A;  4DF9 A;  3LJZ A;  2OW9 A;  4J4M A;  1XFU A;  3B92 A;  5CUH A;  1GE7 A;  3ZVS A;  1IAD A;  1D8F A;  830C A;  2FV5 A;  1XUD A;  3KMC A;  1UTT A;  3N2V A;  3P1V A;  1EB6 A;  4ILW D;  4GR0 A;  3DL1 A;  2N8R A;  5I12 A;  3DPE A;  4I03 A;  1DTH A;  2W15 A;  4PKS A;  1GO7 P;  3B2Z A;  2SRT A;  3LEA A;  1Y8J A;  3UVC A;  4H30 A;  1JAQ A;  4FXY P;  1ZTQ A;  5JMY A;  4PKT A;  5BOY A;  2OI0 A;  1JJ9 A;  1G9K A;  1KBC A;  3KHI A;  1BM6 A;  3ZUK A;  4Q1L A;  2W12 A;  1CK7 A;  4L19 A;  3TVC A;  1SU3 A;  4PKV A;  3HY7 A;  2RJP A;  3Q2G A;  1K7G A;  2X3A A;  5I0L A;  4A3W A;  4DV8 A;  4I35 A;  2L0R A;  1O0Q A;  3B8Z A;  3LIK A;  1Y0V A;  3EHX A;  2DDY A;  2K9C A;  1IAC A;  1R55 A;  4JPA A;  4HMA A;  2DDF A;  4JQG A;  4ZR5 A;  3O2X A;  4AXQ A;  4GWN A;  3LUN A;  2ERP A;  4GUY A;  1D8M A;  1B3D A;  3LK8 A;  5D1S A;  4GWM A;  1QIB A;  1SRP A;  1ZXC A;  2WOA A;  1G49 A;  3KEJ A;  1YP1 A;  1CGF A;  1JH1 A;  1Y93 A;  3VTG A;  1UTZ A;  1K7I A;  1HFC A;  4WKI A;  3L0T A;  1MMQ A;  3OHO A;  3F17 A;  1IAB A;  4ON1 A;  3TSK A;  3DPF A;  4IJO A;  1BIW A;  1OO9 A;  1XFZ A;  2X3B A;  1GO8 P;  3G42 A;  5B5P A;  1QJJ A;  1KUK A;  3AYK A;  4H49 A;  2OY2 A;  1OM6 A;  3V96 B;  1G05 A;  2RJQ A;  4GF1 A;  2W14 A;  1KUI A;  1RM8 A;  4H76 A;  1G12 A;  1BUV M;  5D1U A;  2YIG A;  3WV2 A;  5I43 A;  1I1I P;  1AST A;  1JAO A;  1OM8 A;  4L63 A;  3F16 A;  3NX7 A;  3LJT A;  1H71 P;  2WO8 A;  4FU4 A;  2ERO A;  1R54 A;  3RTS A;  1Z3J A;  1XFX A;  1GKC A;  3EHY A;  3LGP A;  5D2B A;  1AYK A;  1MMR A;  4AYK A;  3HDA P;  2MZE A;  3LQ0 A;  3DSL A;  2WO9 A;  1BSW A;  3ZXH A;  1EUB A;  3GBO A;  1A86 A;  1PWQ A;  3EDZ A;  2K2G A;  1SLN A;  3DWB A;  3E8R A;  4A7B A;  3LMC A;  3EWJ A;  1YQY A;  1OMJ A;  1R1I A;  1C7K A;  3F19 A;  4CTH A;  1UEA A;  2OVZ A;  4IN9 A;  5BOT A;  1XFW A;  5I2Z A;  1G4K A;  2Y6C A;  2J0T A;  4G9L A;  2YB9 A;  4R3V A;  1FLS A;  1FBL A;  1PWU A;  2W13 A;  1I73 A;  2HU6 A;  2USN A;  2FV9 A;  1CIZ A;  3I7G A;  3KME A;  4XM6 A;  1MMB A;  1C8T A;  3WV3 A;  3AIG A;  1MNC A;  4XM7 A;  4WZV A;  3ELM A;  1ND1 A;  1K7Q A;  4XBH A;  2QPJ A;  1GE6 A;  1AKL A;  5BPA A;  3U1R A;  4AIG A;  4GQL A;  1GE5 A;  4H3X A;  2OXZ A;  5I3M A;  4H2E A;  4JP4 A;  1XUR A;  2V4B A;  4PKU A;  3G5C A;  1ZP5 A;  3HBV P;  5I4O A;  1C3I A;  4WKE A;  1HTD A;  1CAQ A;  2Y6D A;  2O36 A;  1AF0 A;  4DD8 A;  4G0D A;  4GR3 A;  2O3E A;  1XUC A;  3LE9 A;  1IAA A;  3KRY A;  1KUF A;  2DW2 A;  1YOU A;  2MLR A;  3O64 A;  4PKW A;  4H84 A;  1JIW P;  3HYG A;  2OW1 A;  3LJG A;  3LIR A;  1L6J A;  1PWV A;  3TS4 A;  5B5O A;  5L79 A;  3WV1 A;  1GXD A;  5LAB A;  2OVX A;  4QKZ A;  4HX3 A;  966C A;  3F18 A;  3HDB A;  2W0D A;  2JT6 A;  2J83 A;  5CXA A;  3OHL A;  2ERQ A;  1IAG A;  1QJI A;  4PKQ A;  2D1N A;  1BKC I;  1JK3 A;  3LUM A;  3F15 A;  1CGE A;  2MLS A;  3KEK A;  2A8H A;  1B8Y A;  4XM8 A;  4IUW A;  1O0T A;  1USN A;  1JAP A;  3EDI A;  1BKC E;  456C A;  2CLT A;  4XCT A;  3HBU P;  2XS3 A;  4GR8 A;  2AYK A;  1BZS A;  1DMT A;  4WF6 A;  4DPE A;  2E2D A;  3USN A;  1HV5 A;  3AYU A;  2OXW A;  2AIG P;  3DNG A;  2CKI A;  3P24 A;  3K7N A;  2OW2 A;  1BQO A;  3HB2 P;  2JT5 A;  1JAN A;  3BA0 A;  1IAE A;  3KEC A;  5D7W A;  1YCM A;  1HOV A;  3RTT A;  2OY4 A;  3TT4 A;  2JIH A;  2PJT A;  3MA2 A;  3LQB A;  1HFS A;  2X7M A;  1ZXV A;  3N2U A;  1PWP A;  2XS4 A;  1R1J A;  1ROS A;  3HY9 A;  1ZVX A;  1J7N A;  1KUG A;  1UMT A;  4EFS A;  3CKI A;  4AUO A;  1CGL A;  1CQR A;  1SLM A;  1OS2 A;  3LIL A;  2TCL A;  1UMS A;  4PKR A;  1JKY A;  4H82 A;  1PWW A;  4JIJ A;  1S4B P;  2OW0 A;  3I7I A;  1CXV A;  3F1A A;  1OM7 A;  1QIA A;  2I47 A;  3EDH A;  2KRJ A;  1MMP A;  1SMP A;  3EDG A;  3SHI A;  2JSD A;  1QIC A;  2X3C A;  2Z2D A;  3VI1 A;  2E3X A;  1RMZ A;  2OXU A;  1KAP P;  1SAT A;  2D1O A;  1I76 A;  3KWV C;  1ATL A;  4L6T A;  4H1Q A;  1KUH A;  1OS9 A;  1GKD A;  5D3C A;  4WK7 A;  5D1T A;  5H8X A;  1R1H A;  1XFY A;  5CZM A;  2MZI A;  1FM1 A;  1D7X A;  1BUD A;  1ZS0 A;  3L0V A;  1A85 A;  1XFV A;  1HY7 A;  1D5J A;  3LKA A;  5L7F A;  4FXQ A;  4JA1 A;  2POJ A;  2MZH A; 
#chains in the Genus database with same CATH topology
 1WNI A;  1BKC A;  2DW0 A;  2OZR A;  2JNP A;  1EAK A;  1QUA A;  1JIZ A;  3K7L A;  2DW1 A;  1Q3A A;  4FVL A;  3DTE A;  1BQQ M;  3Q2H A;  4DF9 A;  3LJZ A;  2OW9 A;  4J4M A;  1XFU A;  3B92 A;  5CUH A;  1GE7 A;  3ZVS A;  1IAD A;  1D8F A;  830C A;  2FV5 A;  1XUD A;  3KMC A;  1UTT A;  3N2V A;  3P1V A;  1EB6 A;  4ILW D;  4GR0 A;  3DL1 A;  1XAX A;  2N8R A;  5I12 A;  3DPE A;  4I03 A;  1DTH A;  2W15 A;  4PKS A;  1GO7 P;  3B2Z A;  2SRT A;  3LEA A;  1Y8J A;  3UVC A;  4H30 A;  1JAQ A;  4FXY P;  1ZTQ A;  5JMY A;  4PKT A;  5BOY A;  3DTI A;  2OI0 A;  1JJ9 A;  1G9K A;  1KBC A;  3KHI A;  1BM6 A;  3ZUK A;  4Q1L A;  2W12 A;  1CK7 A;  4L19 A;  3TVC A;  1SU3 A;  4PKV A;  3HY7 A;  2RJP A;  3Q2G A;  1K7G A;  2X3A A;  5I0L A;  2YUF A;  4A3W A;  4DV8 A;  4I35 A;  2L0R A;  1O0Q A;  3B8Z A;  3LIK A;  1Y0V A;  3EHX A;  2DDY A;  2K9C A;  1IAC A;  1R55 A;  4JPA A;  4HMA A;  2DDF A;  4JQG A;  4ZR5 A;  3O2X A;  4AXQ A;  4GWN A;  3LUN A;  2ERP A;  4GUY A;  1D8M A;  1B3D A;  3LK8 A;  5D1S A;  4GWM A;  1QIB A;  1SRP A;  1ZXC A;  2WOA A;  1G49 A;  3KEJ A;  1YP1 A;  1CGF A;  1JH1 A;  1Y93 A;  3VTG A;  1UTZ A;  1K7I A;  1HFC A;  4WKI A;  3L0T A;  1MMQ A;  3OHO A;  3F17 A;  1IAB A;  4ON1 A;  3TSK A;  3DPF A;  4IJO A;  1BIW A;  1OO9 A;  1XFZ A;  2X3B A;  1GO8 P;  3G42 A;  5B5P A;  1QJJ A;  1KUK A;  3AYK A;  4H49 A;  2OY2 A;  3DTK A;  1OM6 A;  3V96 B;  1G05 A;  2RJQ A;  4GF1 A;  2W14 A;  1KUI A;  1RM8 A;  4H76 A;  1G12 A;  1BUV M;  5D1U A;  2YIG A;  3WV2 A;  5I43 A;  1I1I P;  1AST A;  1JAO A;  1OM8 A;  4L63 A;  3F16 A;  3NX7 A;  3LJT A;  1H71 P;  2WO8 A;  4FU4 A;  2ERO A;  1R54 A;  3RTS A;  1Z3J A;  1XFX A;  1GKC A;  3EHY A;  3LGP A;  5D2B A;  1AYK A;  1MMR A;  4AYK A;  3HDA P;  2MZE A;  3LQ0 A;  3DSL A;  2WO9 A;  1BSW A;  3ZXH A;  1EUB A;  3GBO A;  1A86 A;  1PWQ A;  3EDZ A;  2K2G A;  1SLN A;  3DWB A;  3E8R A;  4A7B A;  3LMC A;  3EWJ A;  1YQY A;  1OMJ A;  1R1I A;  1C7K A;  3F19 A;  4CTH A;  1UEA A;  2OVZ A;  4IN9 A;  5BOT A;  1XFW A;  5I2Z A;  1G4K A;  2Y6C A;  2J0T A;  4G9L A;  2YB9 A;  4R3V A;  1FLS A;  1FBL A;  1PWU A;  2W13 A;  1I73 A;  2HU6 A;  2USN A;  2FV9 A;  1CIZ A;  3I7G A;  3KME A;  4XM6 A;  1MMB A;  1C8T A;  3WV3 A;  3AIG A;  1MNC A;  4XM7 A;  4WZV A;  3ELM A;  1ND1 A;  1K7Q A;  4XBH A;  2QPJ A;  1GE6 A;  1AKL A;  5BPA A;  3U1R A;  4AIG A;  4GQL A;  1GE5 A;  4H3X A;  2OXZ A;  5I3M A;  4H2E A;  4JP4 A;  1XUR A;  2V4B A;  4PKU A;  3G5C A;  1ZP5 A;  3HBV P;  5I4O A;  1C3I A;  4WKE A;  1HTD A;  1CAQ A;  2Y6D A;  2O36 A;  1AF0 A;  4DD8 A;  4G0D A;  4GR3 A;  2O3E A;  1XUC A;  3LE9 A;  1IAA A;  3KRY A;  1KUF A;  2DW2 A;  1YOU A;  1XM5 A;  2MLR A;  3O64 A;  4PKW A;  4H84 A;  1JIW P;  3HYG A;  2OW1 A;  3LJG A;  3LIR A;  1L6J A;  1PWV A;  3TS4 A;  5B5O A;  5L79 A;  3WV1 A;  1GXD A;  5LAB A;  2OVX A;  4QKZ A;  4HX3 A;  966C A;  3F18 A;  3HDB A;  2W0D A;  2JT6 A;  2J83 A;  5CXA A;  3OHL A;  2ERQ A;  1IAG A;  1QJI A;  4L7A A;  4PKQ A;  2D1N A;  1BKC I;  1JK3 A;  3LUM A;  3F15 A;  1CGE A;  2MLS A;  3KEK A;  2A8H A;  1B8Y A;  4XM8 A;  4IUW A;  1O0T A;  1USN A;  1JAP A;  3EDI A;  1BKC E;  456C A;  2CLT A;  4XCT A;  3HBU P;  2XS3 A;  4GR8 A;  2AYK A;  1BZS A;  1DMT A;  4WF6 A;  4DPE A;  2E2D A;  3USN A;  1HV5 A;  3AYU A;  1TVI A;  2OXW A;  2AIG P;  3DNG A;  2CKI A;  3P24 A;  3K7N A;  2OW2 A;  1BQO A;  3HB2 P;  2JT5 A;  1JAN A;  3BA0 A;  1IAE A;  3KEC A;  5D7W A;  1YCM A;  1HOV A;  3RTT A;  2OY4 A;  3TT4 A;  2JIH A;  2PJT A;  3MA2 A;  3LQB A;  1HFS A;  2X7M A;  1ZXV A;  3N2U A;  1PWP A;  2XS4 A;  1R1J A;  1ROS A;  3HY9 A;  1ZVX A;  1J7N A;  1KUG A;  1UMT A;  4EFS A;  3CKI A;  4AUO A;  1CGL A;  1CQR A;  1SLM A;  1OS2 A;  3LIL A;  2TCL A;  1UMS A;  4PKR A;  1JKY A;  4H82 A;  1PWW A;  4JIJ A;  1S4B P;  2OW0 A;  3I7I A;  1CXV A;  3F1A A;  1OM7 A;  1QIA A;  2I47 A;  3EDH A;  2KRJ A;  1MMP A;  1SMP A;  3EDG A;  3SHI A;  2JSD A;  1QIC A;  2X3C A;  2Z2D A;  3VI1 A;  2E3X A;  1RMZ A;  2OXU A;  1KAP P;  1SAT A;  2D1O A;  1I76 A;  3KWV C;  1ATL A;  4L6T A;  1OZ9 A;  4H1Q A;  1KUH A;  1OS9 A;  1GKD A;  5D3C A;  4WK7 A;  5D1T A;  5H8X A;  1R1H A;  1XFY A;  5CZM A;  2MZI A;  1FM1 A;  1D7X A;  1BUD A;  1ZS0 A;  3L0V A;  1A85 A;  1XFV A;  1HY7 A;  1D5J A;  3LKA A;  5L7F A;  4FXQ A;  4JA1 A;  2POJ A;  2MZH A; 
#chains in the Genus database with same CATH homology
 1WNI A;  1BKC A;  2DW0 A;  2OZR A;  2JNP A;  1EAK A;  1QUA A;  1JIZ A;  3K7L A;  2DW1 A;  1Q3A A;  4FVL A;  3DTE A;  1BQQ M;  3Q2H A;  4DF9 A;  3LJZ A;  2OW9 A;  4J4M A;  1XFU A;  3B92 A;  5CUH A;  1GE7 A;  3ZVS A;  1IAD A;  1D8F A;  830C A;  2FV5 A;  1XUD A;  3KMC A;  1UTT A;  3N2V A;  3P1V A;  1EB6 A;  4ILW D;  4GR0 A;  3DL1 A;  2N8R A;  5I12 A;  3DPE A;  4I03 A;  1DTH A;  2W15 A;  4PKS A;  1GO7 P;  3B2Z A;  2SRT A;  3LEA A;  1Y8J A;  3UVC A;  4H30 A;  1JAQ A;  4FXY P;  1ZTQ A;  5JMY A;  4PKT A;  5BOY A;  3DTI A;  2OI0 A;  1JJ9 A;  1G9K A;  1KBC A;  3KHI A;  1BM6 A;  3ZUK A;  4Q1L A;  2W12 A;  1CK7 A;  4L19 A;  3TVC A;  1SU3 A;  4PKV A;  3HY7 A;  2RJP A;  3Q2G A;  1K7G A;  2X3A A;  5I0L A;  2YUF A;  4A3W A;  4DV8 A;  4I35 A;  2L0R A;  1O0Q A;  3B8Z A;  3LIK A;  1Y0V A;  3EHX A;  2DDY A;  2K9C A;  1IAC A;  1R55 A;  4JPA A;  4HMA A;  2DDF A;  4JQG A;  4ZR5 A;  3O2X A;  4AXQ A;  4GWN A;  3LUN A;  2ERP A;  4GUY A;  1D8M A;  1B3D A;  3LK8 A;  5D1S A;  4GWM A;  1QIB A;  1SRP A;  1ZXC A;  2WOA A;  1G49 A;  3KEJ A;  1YP1 A;  1CGF A;  1JH1 A;  1Y93 A;  3VTG A;  1UTZ A;  1K7I A;  1HFC A;  4WKI A;  3L0T A;  1MMQ A;  3OHO A;  3F17 A;  1IAB A;  4ON1 A;  3TSK A;  3DPF A;  4IJO A;  1BIW A;  1OO9 A;  1XFZ A;  2X3B A;  1GO8 P;  3G42 A;  5B5P A;  1QJJ A;  1KUK A;  3AYK A;  4H49 A;  2OY2 A;  3DTK A;  1OM6 A;  3V96 B;  1G05 A;  2RJQ A;  4GF1 A;  2W14 A;  1KUI A;  1RM8 A;  4H76 A;  1G12 A;  1BUV M;  5D1U A;  2YIG A;  3WV2 A;  5I43 A;  1I1I P;  1AST A;  1JAO A;  1OM8 A;  4L63 A;  3F16 A;  3NX7 A;  3LJT A;  1H71 P;  2WO8 A;  4FU4 A;  2ERO A;  1R54 A;  3RTS A;  1Z3J A;  1XFX A;  1GKC A;  3EHY A;  3LGP A;  5D2B A;  1AYK A;  1MMR A;  4AYK A;  3HDA P;  2MZE A;  3LQ0 A;  3DSL A;  2WO9 A;  1BSW A;  3ZXH A;  1EUB A;  3GBO A;  1A86 A;  1PWQ A;  3EDZ A;  2K2G A;  1SLN A;  3DWB A;  3E8R A;  4A7B A;  3LMC A;  3EWJ A;  1YQY A;  1OMJ A;  1R1I A;  1C7K A;  3F19 A;  4CTH A;  1UEA A;  2OVZ A;  4IN9 A;  5BOT A;  1XFW A;  5I2Z A;  1G4K A;  2Y6C A;  2J0T A;  4G9L A;  2YB9 A;  4R3V A;  1FLS A;  1FBL A;  1PWU A;  2W13 A;  1I73 A;  2HU6 A;  2USN A;  2FV9 A;  1CIZ A;  3I7G A;  3KME A;  4XM6 A;  1MMB A;  1C8T A;  3WV3 A;  3AIG A;  1MNC A;  4XM7 A;  4WZV A;  3ELM A;  1ND1 A;  1K7Q A;  4XBH A;  2QPJ A;  1GE6 A;  1AKL A;  5BPA A;  3U1R A;  4AIG A;  4GQL A;  1GE5 A;  4H3X A;  2OXZ A;  5I3M A;  4H2E A;  4JP4 A;  1XUR A;  2V4B A;  4PKU A;  3G5C A;  1ZP5 A;  3HBV P;  5I4O A;  1C3I A;  4WKE A;  1HTD A;  1CAQ A;  2Y6D A;  2O36 A;  1AF0 A;  4DD8 A;  4G0D A;  4GR3 A;  2O3E A;  1XUC A;  3LE9 A;  1IAA A;  3KRY A;  1KUF A;  2DW2 A;  1YOU A;  2MLR A;  3O64 A;  4PKW A;  4H84 A;  1JIW P;  3HYG A;  2OW1 A;  3LJG A;  3LIR A;  1L6J A;  1PWV A;  3TS4 A;  5B5O A;  5L79 A;  3WV1 A;  1GXD A;  5LAB A;  2OVX A;  4QKZ A;  4HX3 A;  966C A;  3F18 A;  3HDB A;  2W0D A;  2JT6 A;  2J83 A;  5CXA A;  3OHL A;  2ERQ A;  1IAG A;  1QJI A;  4L7A A;  4PKQ A;  2D1N A;  1BKC I;  1JK3 A;  3LUM A;  3F15 A;  1CGE A;  2MLS A;  3KEK A;  2A8H A;  1B8Y A;  4XM8 A;  4IUW A;  1O0T A;  1USN A;  1JAP A;  3EDI A;  1BKC E;  456C A;  2CLT A;  4XCT A;  3HBU P;  2XS3 A;  4GR8 A;  2AYK A;  1BZS A;  1DMT A;  4WF6 A;  4DPE A;  2E2D A;  3USN A;  1HV5 A;  3AYU A;  2OXW A;  2AIG P;  3DNG A;  2CKI A;  3P24 A;  3K7N A;  2OW2 A;  1BQO A;  3HB2 P;  2JT5 A;  1JAN A;  3BA0 A;  1IAE A;  3KEC A;  5D7W A;  1YCM A;  1HOV A;  3RTT A;  2OY4 A;  3TT4 A;  2JIH A;  2PJT A;  3MA2 A;  3LQB A;  1HFS A;  2X7M A;  1ZXV A;  3N2U A;  1PWP A;  2XS4 A;  1R1J A;  1ROS A;  3HY9 A;  1ZVX A;  1J7N A;  1KUG A;  1UMT A;  4EFS A;  3CKI A;  4AUO A;  1CGL A;  1CQR A;  1SLM A;  1OS2 A;  3LIL A;  2TCL A;  1UMS A;  4PKR A;  1JKY A;  4H82 A;  1PWW A;  4JIJ A;  1S4B P;  2OW0 A;  3I7I A;  1CXV A;  3F1A A;  1OM7 A;  1QIA A;  2I47 A;  3EDH A;  2KRJ A;  1MMP A;  1SMP A;  3EDG A;  3SHI A;  2JSD A;  1QIC A;  2X3C A;  2Z2D A;  3VI1 A;  2E3X A;  1RMZ A;  2OXU A;  1KAP P;  1SAT A;  2D1O A;  1I76 A;  3KWV C;  1ATL A;  4L6T A;  4H1Q A;  1KUH A;  1OS9 A;  1GKD A;  5D3C A;  4WK7 A;  5D1T A;  5H8X A;  1R1H A;  1XFY A;  5CZM A;  2MZI A;  1FM1 A;  1D7X A;  1BUD A;  1ZS0 A;  3L0V A;  1A85 A;  1XFV A;  1HY7 A;  1D5J A;  3LKA A;  5L7F A;  4FXQ A;  4JA1 A;  2POJ A;  2MZH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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