5JV0F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-038
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
343
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 131
structure length 341
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv0F00
4KK2A 5DIQF 3KRPB 4QPFA 2E4OA 3P5PA 3AQCB 2E8TA 3LEEA 3LGKA 5EASA 3KRAB 5IKHA 3M00A 3NPRA 5IK0A 2Q80A 2F8ZF 1VG3A 3MZVA 4LLTA 2OA6A 3RYWA 3VJDA 2OGDA 2RAHA 3LLWA 2PS8A 4H5DF 3WEFA 1DI1A 3BNXA 3N1VF 3IBAA 5DGNF 4RNQA 5IL3A 2E90A 3TC1A 3RYEA 2I19A 3AQBB 3SDUA 4DXJA 4DI5A 3VJEA 4OMHA 4JVJF 4XQSF 1KIYA 3N5HF 3WCMA 2H8OA 1VG6A 3PH7A 3QQVA 5IMPA 5ILKA 3SDTA 1WL1A 3LOMA 2F7MF 4XQRF 1WMWA 1UBWA 3ZCDA 4PVXF 4LZ3A 1UBYA 4MC3A 4LZCA 4RXCA 3S4JA 3NF2A 3N3DA 4F6VA 3N0FA 3WC9A 3NPKA 3M0GA 3M01A 4KKMA 4OMGA 2ZCRA 4MC8A 5JUZF 3TS7A 5JV1F 3WCBA 1YYSA 1WKZA 2Z50A 1YYTA 1DGPA 2Z4YA 3WCIA 3N6KF 4NFJF 5DHKA 2Z4XA 3OACA 4LTZA 3ZOUA 3LJIA 3WEHA 4KVWA 3TFPA 3SDQA 2AEKA 2ZCOA 5C05A 3LMDA 5ILJA 5EAUA 3Q1OA 2ZEUA 4JYXA 1VG7A 3WCJA 4LIXA 4LOBA 1YJ4A 1V4IA 5H9DA 3QKCA 4KQ5A 5B01A 1JFGA 4LA5A 5A0IA 5ILDA 5AFXA 4LZ0A 5B0LA 1HM4A 3WCGA 3KRCB 4MC0A 3ACWA 2DH4A 3ICZA 4KUXA 4RXAA 3LDWA 1WL3A 3EFQA 3P41A 4GP1A 5IMIA 3KBKA 1N24A 2F8CF 5B0JA 3ZL6A 2E8UA 4F6XA 2AZKA 4NFKF 3G4DA 3WJOA 5B0IA 4E9UA 3ACXA 2Z78A 5DZ2A 5EROA 1HXGA 4GP2A 3LK5A 2P1CA 4N9UA 4LFVF 3UCAA 4LFGA 1WL2A 4DZWA 5AYPA 5IMNA 3PDEA 4OKMA 2O1OA 3IPIA 1YHMA 3N49F 5I1UA 1YYUA 3N1WF 4H5EF 3VJ8A 4LLSA 5HN8A 3KRCA 2FORA 1KIZA 3ACYA 5IN8A 4NKFA 5ILZA 1WY0A 3P8RA 1HM7A 5DJPF 2J1PA 5ILIA 5AHUB 4KQUA 2E93A 2PS6A 3OACB 5HN7A 5JV2F 4XQTF 3KROA 3M02A 2PS4A 1N23A 4K10A 2FTZA 4QXSF 4PVYF 2J1OA 3WSBA 4NUAA 3N0GA 4LA6A 3APZA 5DW7A 1YHLA 2EWGA 5ILHA 4L2XF 3Q30A 3V1XA 2E94A 3WCLA 4EA1A 5B00A 1HXAA 3AQ0A 1RQIA 3BNYA 3CP6A 4JXYA 3VJCA 4DHDA 5DHIA 4P0VA 4RXDA 2OPNA 1UBVA 1VG2A 4P0WA 1YV5A 4KPJA 3G4FA 2E8WA 4RXEA 4H5CF 5EATA 4DWBA 1YYQA 4KPDA 1RQJA 4NFIF 4NKEA 2ONHA 5CG6A 4FJQA 1RTRA 3EZ3A 1EZFA 1N21A 1N22A 2Z4ZA 3WCAA 1ZW5A 2Z4VA 5DJVF 2Q58A 2VF6A 2E95A 3WCEA 3VJ9A 5DGMF 1WL0A 3LZ9A 4KWDA 3TFNA 5CG5A 4NG6A 3LVSA 3WCDA 2J5CA 3WCCA 4DEMF 5E8KA 3RMGA 2ONGA 3P8LA 4WK5A 3AE0A 4JZXA 2PS5A 3DYGA 3DYFA 5B0MA 3KRFA 3ADZA 3B7LA 2Z4WA 3VJBA 3KROB 3N46F 2AETA 3Q2ZA 2PS7A 2F9KF 4EA0A 4HD1A 5A0KA 3SDVA 5E8LA 3WJNA 4LFEA 3WJKA 3ID0A 3SAEA 4KFAA 4KVYA 2Z7HA 5E8HA 5IL8A 3ZMCA 3P5RA 4DWGA 2Q9YA 4N1ZF 3SDRA 2OPMA 3ICMA 2Z52A 2ZCQA 4LXWA 3NRIA 3PYAA 4KQSA 3WCFA 3WEIA 1JFAA 2E91A 4KVIA 3Q2QA 4KVDA 3KB9A 4FP4A 5ERMA 4Q23A 4OKZA 3CC9A 5B0KA 5IM1A 4RYPA 3KRPA 3VJAA 4GAXA 5IVGA 3CKEA 3EGTA 2Q9ZA 4E1EA 5DJRF 3KRAA 3RBMA 3ICNA 4LUUA 5JV0F 4LTVA 4ZQ8A 4EA2A 5HNAA 2F89F 3OABB 3WEJA 2AZLA 3ICKA 5HN9A 2AELA 2AZJA 3WEGA 1YYRA 1V4EA 1N1ZA 5A0JA 1V4HA 2F92F 2QISA 3WSAA 4JZBA 3WCHA 3KRFB 3S9VA 1UBXA 5B02A 3MAVA 4UMJA 4LPGF 1HXCA 4LPHF 2ZEVA 5IK6A 4JXNA 3ASXA 5B03A 2E8XA 3LGZB 5ILYA 1VG4A 2ZY1A 1HX9A 3OYRA 5IKAA 2E8VA 5IK9A 3DYHA 2Z7IA 5JA0F 3W7FA 5ERNA 2ZCSA 3OABA 3WE9A 1N20A 1N1BA 2E92A 4E9ZA 4OGUA 1V4KA 3V1VA 4GA3A 4P0XA 3M9UA 3N5JF 5KSXF 5AELA 3LG5A 1PS1A 3N3LF 1YHKA 3WEKA 5DGSF 1YQ7A 3V66A 3ZMBA 2F94F 1FPSA 3PKOA 4F62A 1V4JA 5ER8A 3PYBA 3N45F 3TFVA 3LSNA
chains in the Genus database with same CATH superfamily
4KK2A 5DIQF 3KRPB 4QPFA 2E4OA 3P5PA 3AQCB 2E8TA 3LEEA 3LGKA 5EASA 3KRAB 5IKHA 3M00A 3NPRA 5IK0A 2Q80A 2F8ZF 1VG3A 3MZVA 4LLTA 2OA6A 3RYWA 3VJDA 2OGDA 2RAHA 3LLWA 2PS8A 4H5DF 3WEFA 1DI1A 3BNXA 3N1VF 3IBAA 5DGNF 4RNQA 5IL3A 2E90A 3TC1A 3RYEA 2I19A 3AQBB 3SDUA 4DXJA 4DI5A 3VJEA 4OMHA 4JVJF 4XQSF 1KIYA 3N5HF 3WCMA 2H8OA 1VG6A 3PH7A 3QQVA 5IMPA 5ILKA 3SDTA 1WL1A 3LOMA 2F7MF 4XQRF 1WMWA 1UBWA 3ZCDA 4PVXF 4LZ3A 1UBYA 4MC3A 4LZCA 4RXCA 3S4JA 3NF2A 3N3DA 4F6VA 3N0FA 3WC9A 3NPKA 3M0GA 3M01A 4KKMA 4OMGA 2ZCRA 4MC8A 5JUZF 3TS7A 5JV1F 3WCBA 1YYSA 1WKZA 2Z50A 1YYTA 1DGPA 2Z4YA 3WCIA 3N6KF 4NFJF 5DHKA 2Z4XA 3OACA 4LTZA 3ZOUA 3LJIA 3WEHA 4KVWA 3TFPA 3SDQA 2AEKA 2ZCOA 5C05A 3LMDA 5ILJA 5EAUA 3Q1OA 2ZEUA 4JYXA 1VG7A 3WCJA 4LIXA 4LOBA 1YJ4A 1V4IA 5H9DA 3QKCA 4KQ5A 5B01A 1JFGA 4LA5A 5A0IA 5ILDA 5AFXA 4LZ0A 5B0LA 1HM4A 3WCGA 3KRCB 4MC0A 3ACWA 2DH4A 3ICZA 4KUXA 4RXAA 3LDWA 1WL3A 3EFQA 3P41A 4GP1A 5IMIA 3KBKA 1N24A 2F8CF 5B0JA 3ZL6A 2E8UA 4F6XA 2AZKA 4NFKF 3G4DA 3WJOA 5B0IA 4E9UA 3ACXA 2Z78A 5DZ2A 5EROA 1HXGA 4GP2A 3LK5A 2P1CA 4N9UA 4LFVF 3UCAA 4LFGA 1WL2A 4DZWA 5AYPA 5IMNA 3PDEA 4OKMA 2O1OA 3IPIA 1YHMA 3N49F 5I1UA 1YYUA 3N1WF 4H5EF 3VJ8A 4LLSA 5HN8A 3KRCA 2FORA 1KIZA 3ACYA 5IN8A 4NKFA 5ILZA 1WY0A 3P8RA 1HM7A 5DJPF 2J1PA 5ILIA 5AHUB 4KQUA 2E93A 2PS6A 3OACB 5HN7A 5JV2F 4XQTF 3KROA 3M02A 2PS4A 1N23A 4K10A 2FTZA 4QXSF 4PVYF 2J1OA 3WSBA 4NUAA 3N0GA 4LA6A 3APZA 5DW7A 1YHLA 2EWGA 5ILHA 4L2XF 3Q30A 3V1XA 2E94A 3WCLA 4EA1A 5B00A 1HXAA 3AQ0A 1RQIA 3BNYA 3CP6A 4JXYA 3VJCA 4DHDA 5DHIA 4P0VA 4RXDA 2OPNA 1UBVA 1VG2A 4P0WA 1YV5A 4KPJA 3G4FA 2E8WA 4RXEA 4H5CF 5EATA 4DWBA 1YYQA 4KPDA 1RQJA 4NFIF 4NKEA 2ONHA 5CG6A 4FJQA 1RTRA 3EZ3A 1EZFA 1N21A 1N22A 2Z4ZA 3WCAA 1ZW5A 2Z4VA 5DJVF 2Q58A 2VF6A 2E95A 3WCEA 3VJ9A 5DGMF 1WL0A 3LZ9A 4KWDA 3TFNA 5CG5A 4NG6A 3LVSA 3WCDA 2J5CA 3WCCA 4DEMF 5E8KA 3RMGA 2ONGA 3P8LA 4WK5A 3AE0A 4JZXA 2PS5A 3DYGA 3DYFA 5B0MA 3KRFA 3ADZA 3B7LA 2Z4WA 3VJBA 3KROB 3N46F 2AETA 3Q2ZA 2PS7A 2F9KF 4EA0A 4HD1A 5A0KA 3SDVA 5E8LA 3WJNA 4LFEA 3WJKA 3ID0A 3SAEA 4KFAA 4KVYA 2Z7HA 5E8HA 5IL8A 3ZMCA 3P5RA 4DWGA 2Q9YA 4N1ZF 3SDRA 2OPMA 3ICMA 2Z52A 2ZCQA 4LXWA 3NRIA 3PYAA 4KQSA 3WCFA 3WEIA 1JFAA 2E91A 4KVIA 3Q2QA 4KVDA 3KB9A 4FP4A 5ERMA 4Q23A 4OKZA 3CC9A 5B0KA 5IM1A 4RYPA 3KRPA 3VJAA 4GAXA 5IVGA 3CKEA 3EGTA 2Q9ZA 4E1EA 5DJRF 3KRAA 3RBMA 3ICNA 4LUUA 5JV0F 4LTVA 4ZQ8A 4EA2A 5HNAA 2F89F 3OABB 3WEJA 2AZLA 3ICKA 5HN9A 2AELA 2AZJA 3WEGA 1YYRA 1V4EA 1N1ZA 5A0JA 1V4HA 2F92F 2QISA 3WSAA 4JZBA 3WCHA 3KRFB 3S9VA 1UBXA 5B02A 3MAVA 4UMJA 4LPGF 1HXCA 4LPHF 2ZEVA 5IK6A 4JXNA 3ASXA 5B03A 2E8XA 3LGZB 5ILYA 1VG4A 2ZY1A 1HX9A 3OYRA 5IKAA 2E8VA 5IK9A 3DYHA 2Z7IA 5JA0F 3W7FA 5ERNA 2ZCSA 3OABA 3WE9A 1N20A 1N1BA 2E92A 4E9ZA 4OGUA 1V4KA 3V1VA 4GA3A 4P0XA 3M9UA 3N5JF 5KSXF 5AELA 3LG5A 1PS1A 3N3LF 1YHKA 3WEKA 5DGSF 1YQ7A 3V66A 3ZMBA 2F94F 1FPSA 3PKOA 4F62A 1V4JA 5ER8A 3PYBA 3N45F 3TFVA 3LSNA
chains in the Genus database with same CATH topology
4KK2A 5DIQF 3KRPB 4QPFA 2E4OA 3P5PA 3AQCB 2E8TA 3LEEA 3LGKA 5EASA 3KRAB 5IKHA 3M00A 3NPRA 5IK0A 2Q80A 2F8ZF 1VG3A 3MZVA 4LLTA 2OA6A 3RYWA 3VJDA 2OGDA 2RAHA 3LLWA 2PS8A 4H5DF 3WEFA 1DI1A 3BNXA 3N1VF 3IBAA 5DGNF 4RNQA 5IL3A 2E90A 3TC1A 3RYEA 2I19A 3AQBB 3SDUA 4DXJA 4DI5A 3VJEA 4OMHA 4JVJF 4XQSF 1KIYA 3N5HF 3WCMA 2H8OA 1VG6A 3PH7A 3QQVA 5IMPA 5ILKA 3SDTA 1WL1A 3LOMA 2F7MF 4XQRF 1WMWA 1UBWA 3ZCDA 4PVXF 4LZ3A 1UBYA 4MC3A 4LZCA 4RXCA 3S4JA 3NF2A 3N3DA 4F6VA 3N0FA 3WC9A 3NPKA 3M0GA 3M01A 4KKMA 4OMGA 2ZCRA 4MC8A 5JUZF 3TS7A 5JV1F 3WCBA 1YYSA 1WKZA 2Z50A 1YYTA 1DGPA 2Z4YA 3WCIA 3N6KF 4NFJF 5DHKA 2Z4XA 3OACA 4LTZA 3ZOUA 3LJIA 3WEHA 4KVWA 3TFPA 3SDQA 2AEKA 2ZCOA 5C05A 3LMDA 5ILJA 5EAUA 3Q1OA 2ZEUA 4JYXA 1VG7A 3WCJA 4LIXA 4LOBA 1YJ4A 1V4IA 5H9DA 3QKCA 4KQ5A 5B01A 1JFGA 4LA5A 5A0IA 5ILDA 5AFXA 4LZ0A 5B0LA 1HM4A 3WCGA 3KRCB 4MC0A 3ACWA 2DH4A 3ICZA 4KUXA 4RXAA 3LDWA 1WL3A 3EFQA 3P41A 4GP1A 5IMIA 3KBKA 1N24A 2F8CF 5B0JA 3ZL6A 2E8UA 4F6XA 2AZKA 4NFKF 3G4DA 3WJOA 5B0IA 4E9UA 3ACXA 2Z78A 5DZ2A 5EROA 1HXGA 4GP2A 3LK5A 2P1CA 4N9UA 4LFVF 3UCAA 4LFGA 1WL2A 4DZWA 5AYPA 5IMNA 3PDEA 4OKMA 2O1OA 3IPIA 1YHMA 3N49F 5I1UA 1YYUA 3N1WF 4H5EF 3VJ8A 4LLSA 5HN8A 3KRCA 2FORA 1KIZA 3ACYA 5IN8A 4NKFA 5ILZA 1WY0A 3P8RA 1HM7A 5DJPF 2J1PA 5ILIA 5AHUB 4KQUA 2E93A 2PS6A 3OACB 5HN7A 5JV2F 4XQTF 3KROA 3M02A 2PS4A 1N23A 4K10A 2FTZA 4QXSF 4PVYF 2J1OA 3WSBA 4NUAA 3N0GA 4LA6A 3APZA 5DW7A 1YHLA 2EWGA 5ILHA 4L2XF 3Q30A 3V1XA 2E94A 3WCLA 4EA1A 5B00A 1HXAA 3AQ0A 1RQIA 3BNYA 3CP6A 4JXYA 3VJCA 4DHDA 5DHIA 4P0VA 4RXDA 2OPNA 1UBVA 1VG2A 4P0WA 1YV5A 4KPJA 3G4FA 2E8WA 4RXEA 4H5CF 5EATA 4DWBA 1YYQA 4KPDA 1RQJA 4NFIF 4NKEA 2ONHA 5CG6A 4FJQA 1RTRA 3EZ3A 1EZFA 1N21A 1N22A 2Z4ZA 3WCAA 1ZW5A 2Z4VA 5DJVF 2Q58A 2VF6A 2E95A 3WCEA 3VJ9A 5DGMF 1WL0A 3LZ9A 4KWDA 3TFNA 5CG5A 4NG6A 3LVSA 3WCDA 2J5CA 3WCCA 4DEMF 5E8KA 3RMGA 2ONGA 3P8LA 4WK5A 3AE0A 4JZXA 2PS5A 3DYGA 3DYFA 5B0MA 3KRFA 3ADZA 3B7LA 2Z4WA 3VJBA 3KROB 3N46F 2AETA 3Q2ZA 2PS7A 2F9KF 4EA0A 4HD1A 5A0KA 3SDVA 5E8LA 3WJNA 4LFEA 3WJKA 3ID0A 3SAEA 4KFAA 4KVYA 2Z7HA 5E8HA 5IL8A 3ZMCA 3P5RA 4DWGA 2Q9YA 4N1ZF 3SDRA 2OPMA 3ICMA 2Z52A 2ZCQA 4LXWA 3NRIA 3PYAA 4KQSA 3WCFA 3WEIA 1JFAA 2E91A 4KVIA 3Q2QA 4KVDA 3KB9A 4FP4A 5ERMA 4Q23A 4OKZA 3CC9A 5B0KA 5IM1A 4RYPA 3KRPA 3VJAA 4GAXA 5IVGA 3CKEA 3EGTA 2Q9ZA 4E1EA 5DJRF 3KRAA 3RBMA 3ICNA 4LUUA 5JV0F 4LTVA 4ZQ8A 4EA2A 5HNAA 2F89F 3OABB 3WEJA 2AZLA 3ICKA 5HN9A 2AELA 2AZJA 3WEGA 1YYRA 1V4EA 1N1ZA 5A0JA 1V4HA 2F92F 2QISA 3WSAA 4JZBA 3WCHA 3KRFB 3S9VA 1UBXA 5B02A 3MAVA 4UMJA 4LPGF 1HXCA 4LPHF 2ZEVA 5IK6A 4JXNA 3ASXA 5B03A 2E8XA 3LGZB 5ILYA 1VG4A 2ZY1A 1HX9A 3OYRA 5IKAA 2E8VA 5IK9A 3DYHA 2Z7IA 5JA0F 3W7FA 5ERNA 2ZCSA 3OABA 3WE9A 1N20A 1N1BA 2E92A 4E9ZA 4OGUA 1V4KA 3V1VA 4GA3A 4P0XA 3M9UA 3N5JF 5KSXF 5AELA 3LG5A 1PS1A 3N3LF 1YHKA 3WEKA 5DGSF 1YQ7A 3V66A 3ZMBA 2F94F 1FPSA 3PKOA 4F62A 1V4JA 5ER8A 3PYBA 3N45F 3TFVA 3LSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KK2 A;  5DIQ F;  3KRP B;  4QPF A;  2E4O A;  3P5P A;  3AQC B;  2E8T A;  3LEE A;  3LGK A;  5EAS A;  3KRA B;  5IKH A;  3M00 A;  3NPR A;  5IK0 A;  2Q80 A;  2F8Z F;  1VG3 A;  3MZV A;  4LLT A;  2OA6 A;  3RYW A;  3VJD A;  2OGD A;  2RAH A;  3LLW A;  2PS8 A;  4H5D F;  3WEF A;  1DI1 A;  3BNX A;  3N1V F;  3IBA A;  5DGN F;  4RNQ A;  5IL3 A;  2E90 A;  3TC1 A;  3RYE A;  2I19 A;  3AQB B;  3SDU A;  4DXJ A;  4DI5 A;  3VJE A;  4OMH A;  4JVJ F;  4XQS F;  1KIY A;  3N5H F;  3WCM A;  2H8O A;  1VG6 A;  3PH7 A;  3QQV A;  5IMP A;  5ILK A;  3SDT A;  1WL1 A;  3LOM A;  2F7M F;  4XQR F;  1WMW A;  1UBW A;  3ZCD A;  4PVX F;  4LZ3 A;  1UBY A;  4MC3 A;  4LZC A;  4RXC A;  3S4J A;  3NF2 A;  3N3D A;  4F6V A;  3N0F A;  3WC9 A;  3NPK A;  3M0G A;  3M01 A;  4KKM A;  4OMG A;  2ZCR A;  4MC8 A;  5JUZ F;  3TS7 A;  5JV1 F;  3WCB A;  1YYS A;  1WKZ A;  2Z50 A;  1YYT A;  1DGP A;  2Z4Y A;  3WCI A;  3N6K F;  4NFJ F;  5DHK A;  2Z4X A;  3OAC A;  4LTZ A;  3ZOU A;  3LJI A;  3WEH A;  4KVW A;  3TFP A;  3SDQ A;  2AEK A;  2ZCO A;  5C05 A;  3LMD A;  5ILJ A;  5EAU A;  3Q1O A;  2ZEU A;  4JYX A;  1VG7 A;  3WCJ A;  4LIX A;  4LOB A;  1YJ4 A;  1V4I A;  5H9D A;  3QKC A;  4KQ5 A;  5B01 A;  1JFG A;  4LA5 A;  5A0I A;  5ILD A;  5AFX A;  4LZ0 A;  5B0L A;  1HM4 A;  3WCG A;  3KRC B;  4MC0 A;  3ACW A;  2DH4 A;  3ICZ A;  4KUX A;  4RXA A;  3LDW A;  1WL3 A;  3EFQ A;  3P41 A;  4GP1 A;  5IMI A;  3KBK A;  1N24 A;  2F8C F;  5B0J A;  3ZL6 A;  2E8U A;  4F6X A;  2AZK A;  4NFK F;  3G4D A;  3WJO A;  5B0I A;  4E9U A;  3ACX A;  2Z78 A;  5DZ2 A;  5ERO A;  1HXG A;  4GP2 A;  3LK5 A;  2P1C A;  4N9U A;  4LFV F;  3UCA A;  4LFG A;  1WL2 A;  4DZW A;  5AYP A;  5IMN A;  3PDE A;  4OKM A;  2O1O A;  3IPI A;  1YHM A;  3N49 F;  5I1U A;  1YYU A;  3N1W F;  4H5E F;  3VJ8 A;  4LLS A;  5HN8 A;  3KRC A;  2FOR A;  1KIZ A;  3ACY A;  5IN8 A;  4NKF A;  5ILZ A;  1WY0 A;  3P8R A;  1HM7 A;  5DJP F;  2J1P A;  5ILI A;  5AHU B;  4KQU A;  2E93 A;  2PS6 A;  3OAC B;  5HN7 A;  5JV2 F;  4XQT F;  3KRO A;  3M02 A;  2PS4 A;  1N23 A;  4K10 A;  2FTZ A;  4QXS F;  4PVY F;  2J1O A;  3WSB A;  4NUA A;  3N0G A;  4LA6 A;  3APZ A;  5DW7 A;  1YHL A;  2EWG A;  5ILH A;  4L2X F;  3Q30 A;  3V1X A;  2E94 A;  3WCL A;  4EA1 A;  5B00 A;  1HXA A;  3AQ0 A;  1RQI A;  3BNY A;  3CP6 A;  4JXY A;  3VJC A;  4DHD A;  5DHI A;  4P0V A;  4RXD A;  2OPN A;  1UBV A;  1VG2 A;  4P0W A;  1YV5 A;  4KPJ A;  3G4F A;  2E8W A;  4RXE A;  4H5C F;  5EAT A;  4DWB A;  1YYQ A;  4KPD A;  1RQJ A;  4NFI F;  4NKE A;  2ONH A;  5CG6 A;  4FJQ A;  1RTR A;  3EZ3 A;  1EZF A;  1N21 A;  1N22 A;  2Z4Z A;  3WCA A;  1ZW5 A;  2Z4V A;  5DJV F;  2Q58 A;  2VF6 A;  2E95 A;  3WCE A;  3VJ9 A;  5DGM F;  1WL0 A;  3LZ9 A;  4KWD A;  3TFN A;  5CG5 A;  4NG6 A;  3LVS A;  3WCD A;  2J5C A;  3WCC A;  4DEM F;  5E8K A;  3RMG A;  2ONG A;  3P8L A;  4WK5 A;  3AE0 A;  4JZX A;  2PS5 A;  3DYG A;  3DYF A;  5B0M A;  3KRF A;  3ADZ A;  3B7L A;  2Z4W A;  3VJB A;  3KRO B;  3N46 F;  2AET A;  3Q2Z A;  2PS7 A;  2F9K F;  4EA0 A;  4HD1 A;  5A0K A;  3SDV A;  5E8L A;  3WJN A;  4LFE A;  3WJK A;  3ID0 A;  3SAE A;  4KFA A;  4KVY A;  2Z7H A;  5E8H A;  5IL8 A;  3ZMC A;  3P5R A;  4DWG A;  2Q9Y A;  4N1Z F;  3SDR A;  2OPM A;  3ICM A;  2Z52 A;  2ZCQ A;  4LXW A;  3NRI A;  3PYA A;  4KQS A;  3WCF A;  3WEI A;  1JFA A;  2E91 A;  4KVI A;  3Q2Q A;  4KVD A;  3KB9 A;  4FP4 A;  5ERM A;  4Q23 A;  4OKZ A;  3CC9 A;  5B0K A;  5IM1 A;  4RYP A;  3KRP A;  3VJA A;  4GAX A;  5IVG A;  3CKE A;  3EGT A;  2Q9Z A;  4E1E A;  5DJR F;  3KRA A;  3RBM A;  3ICN A;  4LUU A;  5JV0 F;  4LTV A;  4ZQ8 A;  4EA2 A;  5HNA A;  2F89 F;  3OAB B;  3WEJ A;  2AZL A;  3ICK A;  5HN9 A;  2AEL A;  2AZJ A;  3WEG A;  1YYR A;  1V4E A;  1N1Z A;  5A0J A;  1V4H A;  2F92 F;  2QIS A;  3WSA A;  4JZB A;  3WCH A;  3KRF B;  3S9V A;  1UBX A;  5B02 A;  3MAV A;  4UMJ A;  4LPG F;  1HXC A;  4LPH F;  2ZEV A;  5IK6 A;  4JXN A;  3ASX A;  5B03 A;  2E8X A;  3LGZ B;  5ILY A;  1VG4 A;  2ZY1 A;  1HX9 A;  3OYR A;  5IKA A;  2E8V A;  5IK9 A;  3DYH A;  2Z7I A;  5JA0 F;  3W7F A;  5ERN A;  2ZCS A;  3OAB A;  3WE9 A;  1N20 A;  1N1B A;  2E92 A;  4E9Z A;  4OGU A;  1V4K A;  3V1V A;  4GA3 A;  4P0X A;  3M9U A;  3N5J F;  5KSX F;  5AEL A;  3LG5 A;  1PS1 A;  3N3L F;  1YHK A;  3WEK A;  5DGS F;  1YQ7 A;  3V66 A;  3ZMB A;  2F94 F;  1FPS A;  3PKO A;  4F62 A;  1V4J A;  5ER8 A;  3PYB A;  3N45 F;  3TFV A;  3LSN A; 
#chains in the Genus database with same CATH topology
 4KK2 A;  5DIQ F;  3KRP B;  4QPF A;  2E4O A;  3P5P A;  3AQC B;  2E8T A;  3LEE A;  3LGK A;  5EAS A;  3KRA B;  5IKH A;  3M00 A;  3NPR A;  5IK0 A;  2Q80 A;  2F8Z F;  1VG3 A;  3MZV A;  4LLT A;  2OA6 A;  3RYW A;  3VJD A;  2OGD A;  2RAH A;  3LLW A;  2PS8 A;  4H5D F;  3WEF A;  1DI1 A;  3BNX A;  3N1V F;  3IBA A;  5DGN F;  4RNQ A;  5IL3 A;  2E90 A;  3TC1 A;  3RYE A;  2I19 A;  3AQB B;  3SDU A;  4DXJ A;  4DI5 A;  3VJE A;  4OMH A;  4JVJ F;  4XQS F;  1KIY A;  3N5H F;  3WCM A;  2H8O A;  1VG6 A;  3PH7 A;  3QQV A;  5IMP A;  5ILK A;  3SDT A;  1WL1 A;  3LOM A;  2F7M F;  4XQR F;  1WMW A;  1UBW A;  3ZCD A;  4PVX F;  4LZ3 A;  1UBY A;  4MC3 A;  4LZC A;  4RXC A;  3S4J A;  3NF2 A;  3N3D A;  4F6V A;  3N0F A;  3WC9 A;  3NPK A;  3M0G A;  3M01 A;  4KKM A;  4OMG A;  2ZCR A;  4MC8 A;  5JUZ F;  3TS7 A;  5JV1 F;  3WCB A;  1YYS A;  1WKZ A;  2Z50 A;  1YYT A;  1DGP A;  2Z4Y A;  3WCI A;  3N6K F;  4NFJ F;  5DHK A;  2Z4X A;  3OAC A;  4LTZ A;  3ZOU A;  3LJI A;  3WEH A;  4KVW A;  3TFP A;  3SDQ A;  2AEK A;  2ZCO A;  5C05 A;  3LMD A;  5ILJ A;  5EAU A;  3Q1O A;  2ZEU A;  4JYX A;  1VG7 A;  3WCJ A;  4LIX A;  4LOB A;  1YJ4 A;  1V4I A;  5H9D A;  3QKC A;  4KQ5 A;  5B01 A;  1JFG A;  4LA5 A;  5A0I A;  5ILD A;  5AFX A;  4LZ0 A;  5B0L A;  1HM4 A;  3WCG A;  3KRC B;  4MC0 A;  3ACW A;  2DH4 A;  3ICZ A;  4KUX A;  4RXA A;  3LDW A;  1WL3 A;  3EFQ A;  3P41 A;  4GP1 A;  5IMI A;  3KBK A;  1N24 A;  2F8C F;  5B0J A;  3ZL6 A;  2E8U A;  4F6X A;  2AZK A;  4NFK F;  3G4D A;  3WJO A;  5B0I A;  4E9U A;  3ACX A;  2Z78 A;  5DZ2 A;  5ERO A;  1HXG A;  4GP2 A;  3LK5 A;  2P1C A;  4N9U A;  4LFV F;  3UCA A;  4LFG A;  1WL2 A;  4DZW A;  5AYP A;  5IMN A;  3PDE A;  4OKM A;  2O1O A;  3IPI A;  1YHM A;  3N49 F;  5I1U A;  1YYU A;  3N1W F;  4H5E F;  3VJ8 A;  4LLS A;  5HN8 A;  3KRC A;  2FOR A;  1KIZ A;  3ACY A;  5IN8 A;  4NKF A;  5ILZ A;  1WY0 A;  3P8R A;  1HM7 A;  5DJP F;  2J1P A;  5ILI A;  5AHU B;  4KQU A;  2E93 A;  2PS6 A;  3OAC B;  5HN7 A;  5JV2 F;  4XQT F;  3KRO A;  3M02 A;  2PS4 A;  1N23 A;  4K10 A;  2FTZ A;  4QXS F;  4PVY F;  2J1O A;  3WSB A;  4NUA A;  3N0G A;  4LA6 A;  3APZ A;  5DW7 A;  1YHL A;  2EWG A;  5ILH A;  4L2X F;  3Q30 A;  3V1X A;  2E94 A;  3WCL A;  4EA1 A;  5B00 A;  1HXA A;  3AQ0 A;  1RQI A;  3BNY A;  3CP6 A;  4JXY A;  3VJC A;  4DHD A;  5DHI A;  4P0V A;  4RXD A;  2OPN A;  1UBV A;  1VG2 A;  4P0W A;  1YV5 A;  4KPJ A;  3G4F A;  2E8W A;  4RXE A;  4H5C F;  5EAT A;  4DWB A;  1YYQ A;  4KPD A;  1RQJ A;  4NFI F;  4NKE A;  2ONH A;  5CG6 A;  4FJQ A;  1RTR A;  3EZ3 A;  1EZF A;  1N21 A;  1N22 A;  2Z4Z A;  3WCA A;  1ZW5 A;  2Z4V A;  5DJV F;  2Q58 A;  2VF6 A;  2E95 A;  3WCE A;  3VJ9 A;  5DGM F;  1WL0 A;  3LZ9 A;  4KWD A;  3TFN A;  5CG5 A;  4NG6 A;  3LVS A;  3WCD A;  2J5C A;  3WCC A;  4DEM F;  5E8K A;  3RMG A;  2ONG A;  3P8L A;  4WK5 A;  3AE0 A;  4JZX A;  2PS5 A;  3DYG A;  3DYF A;  5B0M A;  3KRF A;  3ADZ A;  3B7L A;  2Z4W A;  3VJB A;  3KRO B;  3N46 F;  2AET A;  3Q2Z A;  2PS7 A;  2F9K F;  4EA0 A;  4HD1 A;  5A0K A;  3SDV A;  5E8L A;  3WJN A;  4LFE A;  3WJK A;  3ID0 A;  3SAE A;  4KFA A;  4KVY A;  2Z7H A;  5E8H A;  5IL8 A;  3ZMC A;  3P5R A;  4DWG A;  2Q9Y A;  4N1Z F;  3SDR A;  2OPM A;  3ICM A;  2Z52 A;  2ZCQ A;  4LXW A;  3NRI A;  3PYA A;  4KQS A;  3WCF A;  3WEI A;  1JFA A;  2E91 A;  4KVI A;  3Q2Q A;  4KVD A;  3KB9 A;  4FP4 A;  5ERM A;  4Q23 A;  4OKZ A;  3CC9 A;  5B0K A;  5IM1 A;  4RYP A;  3KRP A;  3VJA A;  4GAX A;  5IVG A;  3CKE A;  3EGT A;  2Q9Z A;  4E1E A;  5DJR F;  3KRA A;  3RBM A;  3ICN A;  4LUU A;  5JV0 F;  4LTV A;  4ZQ8 A;  4EA2 A;  5HNA A;  2F89 F;  3OAB B;  3WEJ A;  2AZL A;  3ICK A;  5HN9 A;  2AEL A;  2AZJ A;  3WEG A;  1YYR A;  1V4E A;  1N1Z A;  5A0J A;  1V4H A;  2F92 F;  2QIS A;  3WSA A;  4JZB A;  3WCH A;  3KRF B;  3S9V A;  1UBX A;  5B02 A;  3MAV A;  4UMJ A;  4LPG F;  1HXC A;  4LPH F;  2ZEV A;  5IK6 A;  4JXN A;  3ASX A;  5B03 A;  2E8X A;  3LGZ B;  5ILY A;  1VG4 A;  2ZY1 A;  1HX9 A;  3OYR A;  5IKA A;  2E8V A;  5IK9 A;  3DYH A;  2Z7I A;  5JA0 F;  3W7F A;  5ERN A;  2ZCS A;  3OAB A;  3WE9 A;  1N20 A;  1N1B A;  2E92 A;  4E9Z A;  4OGU A;  1V4K A;  3V1V A;  4GA3 A;  4P0X A;  3M9U A;  3N5J F;  5KSX F;  5AEL A;  3LG5 A;  1PS1 A;  3N3L F;  1YHK A;  3WEK A;  5DGS F;  1YQ7 A;  3V66 A;  3ZMB A;  2F94 F;  1FPS A;  3PKO A;  4F62 A;  1V4J A;  5ER8 A;  3PYB A;  3N45 F;  3TFV A;  3LSN A; 
#chains in the Genus database with same CATH homology
 4KK2 A;  5DIQ F;  3KRP B;  4QPF A;  2E4O A;  3P5P A;  3AQC B;  2E8T A;  3LEE A;  3LGK A;  5EAS A;  3KRA B;  5IKH A;  3M00 A;  3NPR A;  5IK0 A;  2Q80 A;  2F8Z F;  1VG3 A;  3MZV A;  4LLT A;  2OA6 A;  3RYW A;  3VJD A;  2OGD A;  2RAH A;  3LLW A;  2PS8 A;  4H5D F;  3WEF A;  1DI1 A;  3BNX A;  3N1V F;  3IBA A;  5DGN F;  4RNQ A;  5IL3 A;  2E90 A;  3TC1 A;  3RYE A;  2I19 A;  3AQB B;  3SDU A;  4DXJ A;  4DI5 A;  3VJE A;  4OMH A;  4JVJ F;  4XQS F;  1KIY A;  3N5H F;  3WCM A;  2H8O A;  1VG6 A;  3PH7 A;  3QQV A;  5IMP A;  5ILK A;  3SDT A;  1WL1 A;  3LOM A;  2F7M F;  4XQR F;  1WMW A;  1UBW A;  3ZCD A;  4PVX F;  4LZ3 A;  1UBY A;  4MC3 A;  4LZC A;  4RXC A;  3S4J A;  3NF2 A;  3N3D A;  4F6V A;  3N0F A;  3WC9 A;  3NPK A;  3M0G A;  3M01 A;  4KKM A;  4OMG A;  2ZCR A;  4MC8 A;  5JUZ F;  3TS7 A;  5JV1 F;  3WCB A;  1YYS A;  1WKZ A;  2Z50 A;  1YYT A;  1DGP A;  2Z4Y A;  3WCI A;  3N6K F;  4NFJ F;  5DHK A;  2Z4X A;  3OAC A;  4LTZ A;  3ZOU A;  3LJI A;  3WEH A;  4KVW A;  3TFP A;  3SDQ A;  2AEK A;  2ZCO A;  5C05 A;  3LMD A;  5ILJ A;  5EAU A;  3Q1O A;  2ZEU A;  4JYX A;  1VG7 A;  3WCJ A;  4LIX A;  4LOB A;  1YJ4 A;  1V4I A;  5H9D A;  3QKC A;  4KQ5 A;  5B01 A;  1JFG A;  4LA5 A;  5A0I A;  5ILD A;  5AFX A;  4LZ0 A;  5B0L A;  1HM4 A;  3WCG A;  3KRC B;  4MC0 A;  3ACW A;  2DH4 A;  3ICZ A;  4KUX A;  4RXA A;  3LDW A;  1WL3 A;  3EFQ A;  3P41 A;  4GP1 A;  5IMI A;  3KBK A;  1N24 A;  2F8C F;  5B0J A;  3ZL6 A;  2E8U A;  4F6X A;  2AZK A;  4NFK F;  3G4D A;  3WJO A;  5B0I A;  4E9U A;  3ACX A;  2Z78 A;  5DZ2 A;  5ERO A;  1HXG A;  4GP2 A;  3LK5 A;  2P1C A;  4N9U A;  4LFV F;  3UCA A;  4LFG A;  1WL2 A;  4DZW A;  5AYP A;  5IMN A;  3PDE A;  4OKM A;  2O1O A;  3IPI A;  1YHM A;  3N49 F;  5I1U A;  1YYU A;  3N1W F;  4H5E F;  3VJ8 A;  4LLS A;  5HN8 A;  3KRC A;  2FOR A;  1KIZ A;  3ACY A;  5IN8 A;  4NKF A;  5ILZ A;  1WY0 A;  3P8R A;  1HM7 A;  5DJP F;  2J1P A;  5ILI A;  5AHU B;  4KQU A;  2E93 A;  2PS6 A;  3OAC B;  5HN7 A;  5JV2 F;  4XQT F;  3KRO A;  3M02 A;  2PS4 A;  1N23 A;  4K10 A;  2FTZ A;  4QXS F;  4PVY F;  2J1O A;  3WSB A;  4NUA A;  3N0G A;  4LA6 A;  3APZ A;  5DW7 A;  1YHL A;  2EWG A;  5ILH A;  4L2X F;  3Q30 A;  3V1X A;  2E94 A;  3WCL A;  4EA1 A;  5B00 A;  1HXA A;  3AQ0 A;  1RQI A;  3BNY A;  3CP6 A;  4JXY A;  3VJC A;  4DHD A;  5DHI A;  4P0V A;  4RXD A;  2OPN A;  1UBV A;  1VG2 A;  4P0W A;  1YV5 A;  4KPJ A;  3G4F A;  2E8W A;  4RXE A;  4H5C F;  5EAT A;  4DWB A;  1YYQ A;  4KPD A;  1RQJ A;  4NFI F;  4NKE A;  2ONH A;  5CG6 A;  4FJQ A;  1RTR A;  3EZ3 A;  1EZF A;  1N21 A;  1N22 A;  2Z4Z A;  3WCA A;  1ZW5 A;  2Z4V A;  5DJV F;  2Q58 A;  2VF6 A;  2E95 A;  3WCE A;  3VJ9 A;  5DGM F;  1WL0 A;  3LZ9 A;  4KWD A;  3TFN A;  5CG5 A;  4NG6 A;  3LVS A;  3WCD A;  2J5C A;  3WCC A;  4DEM F;  5E8K A;  3RMG A;  2ONG A;  3P8L A;  4WK5 A;  3AE0 A;  4JZX A;  2PS5 A;  3DYG A;  3DYF A;  5B0M A;  3KRF A;  3ADZ A;  3B7L A;  2Z4W A;  3VJB A;  3KRO B;  3N46 F;  2AET A;  3Q2Z A;  2PS7 A;  2F9K F;  4EA0 A;  4HD1 A;  5A0K A;  3SDV A;  5E8L A;  3WJN A;  4LFE A;  3WJK A;  3ID0 A;  3SAE A;  4KFA A;  4KVY A;  2Z7H A;  5E8H A;  5IL8 A;  3ZMC A;  3P5R A;  4DWG A;  2Q9Y A;  4N1Z F;  3SDR A;  2OPM A;  3ICM A;  2Z52 A;  2ZCQ A;  4LXW A;  3NRI A;  3PYA A;  4KQS A;  3WCF A;  3WEI A;  1JFA A;  2E91 A;  4KVI A;  3Q2Q A;  4KVD A;  3KB9 A;  4FP4 A;  5ERM A;  4Q23 A;  4OKZ A;  3CC9 A;  5B0K A;  5IM1 A;  4RYP A;  3KRP A;  3VJA A;  4GAX A;  5IVG A;  3CKE A;  3EGT A;  2Q9Z A;  4E1E A;  5DJR F;  3KRA A;  3RBM A;  3ICN A;  4LUU A;  5JV0 F;  4LTV A;  4ZQ8 A;  4EA2 A;  5HNA A;  2F89 F;  3OAB B;  3WEJ A;  2AZL A;  3ICK A;  5HN9 A;  2AEL A;  2AZJ A;  3WEG A;  1YYR A;  1V4E A;  1N1Z A;  5A0J A;  1V4H A;  2F92 F;  2QIS A;  3WSA A;  4JZB A;  3WCH A;  3KRF B;  3S9V A;  1UBX A;  5B02 A;  3MAV A;  4UMJ A;  4LPG F;  1HXC A;  4LPH F;  2ZEV A;  5IK6 A;  4JXN A;  3ASX A;  5B03 A;  2E8X A;  3LGZ B;  5ILY A;  1VG4 A;  2ZY1 A;  1HX9 A;  3OYR A;  5IKA A;  2E8V A;  5IK9 A;  3DYH A;  2Z7I A;  5JA0 F;  3W7F A;  5ERN A;  2ZCS A;  3OAB A;  3WE9 A;  1N20 A;  1N1B A;  2E92 A;  4E9Z A;  4OGU A;  1V4K A;  3V1V A;  4GA3 A;  4P0X A;  3M9U A;  3N5J F;  5KSX F;  5AEL A;  3LG5 A;  1PS1 A;  3N3L F;  1YHK A;  3WEK A;  5DGS F;  1YQ7 A;  3V66 A;  3ZMB A;  2F94 F;  1FPS A;  3PKO A;  4F62 A;  1V4J A;  5ER8 A;  3PYB A;  3N45 F;  3TFV A;  3LSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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