5K4KA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-4
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
228
structure length
228
Chain Sequence
DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
source organism Klebsiella pneumoniae
molecule tags Hydrolase
molecule keywords Metallo-beta-lactamase type 2
total genus 70
structure length 228
sequence length 228
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-05-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4kA00
2FU7A 3SD9A 3ADRA 4EXYA 2P97A 2NZFA 4YSLA 4U4LA 2NXAA 4PVTA 4C09A 4RAMA 4D1WA 2CBNA 5AYAA 4UWRB 1YCFA 3X2XA 3T9MA 2FHXA 3PY6A 4C1HA 4EYFA 5LSCA 1M2XA 5ACXA 5ACQA 2M5CA 4Z60A 3PG4A 4NQ5A 4EYBA 2YZ3A 4Z5YA 4J5HA 3ZQ4A 4AX1B 4ZO2A 1KO2A 3IE0A 4UWOB 1WUOA 4NQ4A 2Y87A 2GMNA 5FQCA 4C1FA 3SBLA 1KO3A 4D1UA 1WW1A 3I13A 4Z5ZA 4XUKA 4XWTA 2UYXA 3Q6VA 2DOOA 3QH8A 2WYMC 2YNTA 1E5DA 5ACUA 1SMLA 4RM5A 5AXRA 4RBSA 1XM8A 5A87A 2NYPA 3I15A 2Y8BA 4F6ZA 3IE1A 4UWSB 5LCHA 3ZWFA 2M5DA 3KL7A 4TZBA 4YSKA 5HIQA 2YCBA 4ZNBA 2FU8A 1DDKA 2ZZIA 4EYLA 2VW8A 3SFPA 5B3RA 4C1EA 2GFKA 4YSBA 5K4NA 3SRXA 2BFLA 4ZEJA 3LVZA 1L9YA 1JJTA 3I11A 1JJEA 3IDZA 1ZKPA 4Z7RA 3IE2A 4DIKA 4HL1A 1ZTCA 4H0DA 2FU9A 5FQBA 3R2UA 5EHTA 4UBQA 2AIOA 5HH6A 4CHLA 1WUPA 2YNWA 5FQAA 4FR7A 2XR1A 1A7TA 4V0HA 1YCGA 2GKLA 5LCAA 3WXCA 5EVDA 1QH5A 4NQ6A 3AF6A 5EVKA 3P2UA 2I7VA 2BFZA 3TP9A 4GYQA 4P62A 4KEQA 1VJNA 3S0ZA 4O98A 1ZNBA 5ACPA 2GFJA 4UA4A 2FHXB 2P18A 2P1EA 3T3OA 3BC2A 5LCFA 5A0TA 4UWPB 4FSBA 2BMIA 2BG8B 1MQOA 2H6AA 3T3NA 5LS3A 3DHAA 4TZFA 3MD7A 2Q42A 2A7MA 1YCHA 2YNVA 5A0VA 3JXPA 3ZR9A 2BG8A 4Z6XA 2BC2A 5EV8A 4TYTA 3F9OA 4NQ2A 3PY5A 3X30A 5AEBA 5KIKA 5B15A 4D1TA 4AWYB 4J5FA 3BV6A 4EFZA 3RKKA 1Y44A 5HIOA 4PVOA 4EY2A 2BR6A 2BTNA 2BG6A 1QH3A 1JT1A 3FCZA 4C1CA 4D02A 2R2DA 4C1DA 5LE1A 3X2ZA 3IOGA 5LLDA 1VMEA 3G1PA 4AX0B 2QDSA 2ZNBA 4BZ3A 1X8IA 1A8TA 5K0WA 4B87A 2QINA 4AD9A 4UAMA 5ACVA 1BC2A 5K4MA 3AF5A 2YNUA 1WRAA 4RL0A 2BG7A 1BMCA 2FK6A 3IELA 4DILA 1HLKA 3FAIA 3KNSA 1DXKA 3X2YA 2Q0IA 3BK2A 5ACSA 2YNTB 4BP0A 3VPEA 5ACTA 2BGAA 4TYFA 2YNVB 4WD6A 2BIBA 2OHHA 4JO0A 5ACRA 5LMCA 2AZ4A 2FU6A 3IEKA 3RPCA 4RAWA 2Q9UA 2BFKA 5HISA 3L6NA 4RL2A 1BVTA 2E7YA 5EWAA 2FM6A 1KR3A 5EW0A 4F6HA 4D1VA 5DPXA 2HB9A 5AXOA 5HH4A 3KNRA 2WHGA 2XF4A 5B1UA 2BFZB 2WYMA 3H3EA 3SPUA 4AWZA 2ZO4A 3ZNBA 2P4ZA 4LE6A 2Y8AA 2I7XA 2I7TA 5AHOA 5EH9A 2QDTA 4Z67A 5ACWA 5AHRA 5EV6A 4EXSA 2GCUA 1DD6A 5HH5A 3I0VA 2Q0JA 5LM6A 2OHJA 5K4KA 2WYLA 2WRSA 4C1GA 3DHCA 3RKJA 1VGNA 5KILA 4XWWA 4TZEA 4TZ9A 1X8HA 2QEDA 2NZEA 3VQZA 3IOFA 3A4YA 2DKFA 3DH8A 4KEPA 4GCWA 5A5ZA 3BK1A 2ZWRA 4HL2A 3ESHA 3AJ3A 2OHIA 5HIPA 4HKYA 2QJSA 3I14A 3SW3A 1K07A 3DHBA 1P9EA 4ZO3A 1XTOA 4FEKA 1X8GA 5EVBA 5IQKA 3IEMA 4GYUA 2BG2A
chains in the Genus database with same CATH superfamily
2FU7A 3SD9A 2CG2A 3ADRA 4EXYA 5A23A 2P97A 2NZFA 4YSLA 4U4LA 2NXAA 4PVTA 4C09A 4RAMA 4D1WA 2CBNA 4PDXA 5AYAA 4UWRB 1YCFA 3X2XA 3T9MA 2FHXA 3PY6A 4C1HA 4EYFA 5LSCA 1M2XA 5ACXA 5ACQA 2M5CA 4Z60A 3PG4A 4NQ5A 4EYBA 2YZ3A 4Z5YA 4J5HA 3ZQ4A 4AX1B 4ZO2A 1KO2A 3IE0A 4UWOB 1WUOA 4NQ4A 2Y87A 2GMNA 5FQCA 4C1FA 3SBLA 1KO3A 4D1UA 1WW1A 3I13A 4Z5ZA 4AV7A 4XUKA 4XWTA 2UYXA 3Q6VA 2DOOA 3QH8A 2WYMC 2YNTA 1E5DA 5ACUA 1SMLA 4RM5A 5AXRA 4RBSA 1XM8A 5A87A 2NYPA 3I15A 2Y8BA 4F6ZA 3IE1A 4UWSB 5LCHA 3ZWFA 2M5DA 3KL7A 4TZBA 4YSKA 5HIQA 2YCBA 4ZNBA 2FU8A 1DDKA 2ZZIA 4EYLA 2VW8A 3SFPA 5B3RA 4C1EA 2GFKA 4YSBA 5K4NA 3SRXA 2BFLA 4ZEJA 3LVZA 1L9YA 1JJTA 3I11A 1JJEA 3IDZA 1ZKPA 4Z7RA 3IE2A 4DIKA 4HL1A 1ZTCA 4H0DA 2FU9A 5FQBA 3R2UA 5EHTA 4UBQA 5AIJA 2AIOA 5HH6A 4CHLA 1WUPA 2YNWA 5FQAA 4FR7A 2XR1A 1A7TA 4V0HA 2GKLA 1YCGA 5LCAA 3WXCA 5EVDA 1QH5A 4NQ6A 3AF6A 5EVKA 3P2UA 2I7VA 2BFZA 3TP9A 4GYQA 4P62A 4KEQA 1VJNA 3S0ZA 4O98A 1ZNBA 5ACPA 2GFJA 4UA4A 2FHXB 2P18A 2P1EA 3T3OA 3BC2A 5LCFA 5A0TA 4UWPB 4FSBA 2BMIA 2BG8B 1MQOA 2H6AA 3T3NA 5LS3A 3DHAA 4TZFA 3MD7A 2Q42A 2A7MA 1YCHA 2YNVA 5A0VA 3JXPA 3ZR9A 2BG8A 4Z6XA 2BC2A 5EV8A 4TYTA 3F9OA 4NQ2A 3PY5A 3X30A 5AEBA 5KIKA 5B15A 4D1TA 4AWYB 4J5FA 3BV6A 4EFZA 3RKKA 1Y44A 5HIOA 4PVOA 4EY2A 2BR6A 2BTNA 2BG6A 1QH3A 1JT1A 3FCZA 4C1CA 2BG2A 4D02A 2R2DA 4C1DA 5LE1A 3X2ZA 3IOGA 5LLDA 1VMEA 3G1PA 4AX0B 2CFUA 2QDSA 2ZNBA 4BZ3A 1X8IA 1A8TA 5K0WA 4B87A 2QINA 4AD9A 4UAMA 5ACVA 1BC2A 5K4MA 2CFZA 3AF5A 2YNUA 1WRAA 4RL0A 2BG7A 1BMCA 2FK6A 3IELA 4DILA 1HLKA 3FAIA 3KNSA 1DXKA 3X2YA 2Q0IA 3BK2A 5ACSA 2YNTB 4BP0A 3VPEA 5ACTA 2BGAA 4TYFA 2YNVB 4WD6A 2BIBA 2OHHA 4JO0A 5ACRA 5LMCA 2AZ4A 2FU6A 3IEKA 3RPCA 4RAWA 2Q9UA 2BFKA 5HISA 3L6NA 4RL2A 1BVTA 2E7YA 5EWAA 2FM6A 1KR3A 5EW0A 4F6HA 4D1VA 5DPXA 2HB9A 4NURA 5AXOA 5HH4A 2CG3A 3KNRA 2WHGA 2XF4A 5B1UA 2BFZB 2WYMA 3H3EA 3SPUA 4AWZA 2ZO4A 3ZNBA 2P4ZA 4LE6A 2Y8AA 2I7XA 2I7TA 5AHOA 5EH9A 2QDTA 4Z67A 5ACWA 5AHRA 5EV6A 4EXSA 2GCUA 1DD6A 5HH5A 3I0VA 2Q0JA 5LM6A 2OHJA 5K4KA 2WYLA 2WRSA 4C1GA 3DHCA 3RKJA 1VGNA 5KILA 4XWWA 4TZEA 4TZ9A 1X8HA 2QEDA 2NZEA 3VQZA 3IOFA 3A4YA 2DKFA 3DH8A 4KEPA 4GCWA 5A5ZA 3BK1A 2ZWRA 4HL2A 3ESHA 3AJ3A 2OHIA 5HIPA 4HKYA 2QJSA 3I14A 3SW3A 1K07A 5AJLA 3DHBA 1P9EA 4ZO3A 4AXHA 1XTOA 4FEKA 1X8GA 5EVBA 5IQKA 3IEMA 4GYUA 2YHEA
chains in the Genus database with same CATH topology
2FU7A 3SD9A 3ADRA 4EXYA 2P97A 2NZFA 4YSLA 4U4LA 2NXAA 4PVTA 4C09A 4RAMA 4D1WA 2CBNA 5AYAA 4UWRB 1YCFA 3X2XA 3T9MA 2FHXA 3PY6A 4C1HA 4EYFA 5LSCA 1M2XA 5ACXA 5ACQA 2M5CA 4Z60A 3PG4A 4NQ5A 4EYBA 2YZ3A 4Z5YA 4J5HA 3ZQ4A 4AX1B 4ZO2A 1KO2A 3IE0A 4UWOB 1WUOA 4NQ4A 2Y87A 2GMNA 5FQCA 4C1FA 3SBLA 1KO3A 4D1UA 1WW1A 3I13A 4Z5ZA 4XUKA 4XWTA 2UYXA 3Q6VA 2DOOA 3QH8A 2WYMC 2YNTA 1E5DA 5ACUA 1SMLA 4RM5A 5AXRA 4RBSA 1XM8A 5A87A 2NYPA 3I15A 2Y8BA 4F6ZA 3IE1A 4UWSB 5LCHA 3ZWFA 2M5DA 3KL7A 4TZBA 4YSKA 5HIQA 2YCBA 4ZNBA 2FU8A 1DDKA 2ZZIA 4EYLA 2VW8A 3SFPA 5B3RA 4C1EA 2GFKA 4YSBA 5K4NA 3SRXA 2BFLA 4ZEJA 3LVZA 1L9YA 1JJTA 3I11A 1JJEA 3IDZA 1ZKPA 4Z7RA 3IE2A 4DIKA 4HL1A 1ZTCA 4H0DA 2FU9A 5FQBA 3R2UA 5EHTA 4UBQA 2AIOA 5HH6A 4CHLA 1WUPA 2YNWA 5FQAA 4FR7A 2XR1A 1A7TA 4V0HA 1YCGA 2GKLA 5LCAA 3WXCA 5EVDA 1QH5A 4NQ6A 3AF6A 5EVKA 3P2UA 2I7VA 2BFZA 3TP9A 4GYQA 4P62A 4KEQA 1VJNA 3S0ZA 4O98A 1ZNBA 5ACPA 2GFJA 4UA4A 2FHXB 2P18A 2P1EA 3T3OA 3BC2A 5LCFA 5A0TA 4UWPB 4FSBA 2BMIA 2BG8B 1MQOA 2H6AA 3T3NA 5LS3A 3DHAA 4TZFA 3MD7A 2Q42A 2A7MA 1YCHA 2YNVA 5A0VA 3JXPA 3ZR9A 2BG8A 4Z6XA 2BC2A 5EV8A 4TYTA 3F9OA 4NQ2A 3PY5A 3X30A 5AEBA 5KIKA 5B15A 4D1TA 4AWYB 4J5FA 3BV6A 4EFZA 3RKKA 1Y44A 5HIOA 4PVOA 4EY2A 2BR6A 2BTNA 2BG6A 1QH3A 1JT1A 3FCZA 4C1CA 4D02A 2R2DA 4C1DA 5LE1A 3X2ZA 3IOGA 5LLDA 1VMEA 3G1PA 4AX0B 2QDSA 2ZNBA 4BZ3A 1X8IA 1A8TA 5K0WA 4B87A 2QINA 4AD9A 4UAMA 5ACVA 1BC2A 5K4MA 3AF5A 2YNUA 1WRAA 4RL0A 2BG7A 1BMCA 2FK6A 3IELA 4DILA 1HLKA 3FAIA 3KNSA 1DXKA 3X2YA 2Q0IA 3BK2A 5ACSA 2YNTB 4BP0A 3VPEA 5ACTA 2BGAA 4TYFA 2YNVB 4WD6A 2BIBA 2OHHA 4JO0A 5ACRA 5LMCA 2AZ4A 2FU6A 3IEKA 3RPCA 4RAWA 2Q9UA 2BFKA 5HISA 3L6NA 4RL2A 1BVTA 2E7YA 5EWAA 2FM6A 1KR3A 5EW0A 4F6HA 4D1VA 5DPXA 2HB9A 5AXOA 5HH4A 3KNRA 2WHGA 2XF4A 5B1UA 2BFZB 2WYMA 3H3EA 3SPUA 4AWZA 2ZO4A 3ZNBA 2P4ZA 4LE6A 2Y8AA 2I7XA 2I7TA 5AHOA 5EH9A 2QDTA 4Z67A 5ACWA 5AHRA 5EV6A 4EXSA 2GCUA 1DD6A 5HH5A 3I0VA 2Q0JA 5LM6A 2OHJA 5K4KA 2WYLA 2WRSA 4C1GA 3DHCA 3RKJA 1VGNA 5KILA 4XWWA 4TZEA 4TZ9A 1X8HA 2QEDA 2NZEA 3VQZA 3IOFA 3A4YA 2DKFA 3DH8A 4KEPA 4GCWA 5A5ZA 3BK1A 2ZWRA 4HL2A 3ESHA 3AJ3A 2OHIA 5HIPA 4HKYA 2QJSA 3I14A 3SW3A 1K07A 3DHBA 1P9EA 4ZO3A 1XTOA 4FEKA 1X8GA 5EVBA 5IQKA 3IEMA 4GYUA 2BG2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FU7 A;  3SD9 A;  3ADR A;  4EXY A;  2P97 A;  2NZF A;  4YSL A;  4U4L A;  2NXA A;  4PVT A;  4C09 A;  4RAM A;  4D1W A;  2CBN A;  5AYA A;  4UWR B;  1YCF A;  3X2X A;  3T9M A;  2FHX A;  3PY6 A;  4C1H A;  4EYF A;  5LSC A;  1M2X A;  5ACX A;  5ACQ A;  2M5C A;  4Z60 A;  3PG4 A;  4NQ5 A;  4EYB A;  2YZ3 A;  4Z5Y A;  4J5H A;  3ZQ4 A;  4AX1 B;  4ZO2 A;  1KO2 A;  3IE0 A;  4UWO B;  1WUO A;  4NQ4 A;  2Y87 A;  2GMN A;  5FQC A;  4C1F A;  3SBL A;  1KO3 A;  4D1U A;  1WW1 A;  3I13 A;  4Z5Z A;  4XUK A;  4XWT A;  2UYX A;  3Q6V A;  2DOO A;  3QH8 A;  2WYM C;  2YNT A;  1E5D A;  5ACU A;  1SML A;  4RM5 A;  5AXR A;  4RBS A;  1XM8 A;  5A87 A;  2NYP A;  3I15 A;  2Y8B A;  4F6Z A;  3IE1 A;  4UWS B;  5LCH A;  3ZWF A;  2M5D A;  3KL7 A;  4TZB A;  4YSK A;  5HIQ A;  2YCB A;  4ZNB A;  2FU8 A;  1DDK A;  2ZZI A;  4EYL A;  2VW8 A;  3SFP A;  5B3R A;  4C1E A;  2GFK A;  4YSB A;  5K4N A;  3SRX A;  2BFL A;  4ZEJ A;  3LVZ A;  1L9Y A;  1JJT A;  3I11 A;  1JJE A;  3IDZ A;  1ZKP A;  4Z7R A;  3IE2 A;  4DIK A;  4HL1 A;  1ZTC A;  4H0D A;  2FU9 A;  5FQB A;  3R2U A;  5EHT A;  4UBQ A;  2AIO A;  5HH6 A;  4CHL A;  1WUP A;  2YNW A;  5FQA A;  4FR7 A;  2XR1 A;  1A7T A;  4V0H A;  1YCG A;  2GKL A;  5LCA A;  3WXC A;  5EVD A;  1QH5 A;  4NQ6 A;  3AF6 A;  5EVK A;  3P2U A;  2I7V A;  2BFZ A;  3TP9 A;  4GYQ A;  4P62 A;  4KEQ A;  1VJN A;  3S0Z A;  4O98 A;  1ZNB A;  5ACP A;  2GFJ A;  4UA4 A;  2FHX B;  2P18 A;  2P1E A;  3T3O A;  3BC2 A;  5LCF A;  5A0T A;  4UWP B;  4FSB A;  2BMI A;  2BG8 B;  1MQO A;  2H6A A;  3T3N A;  5LS3 A;  3DHA A;  4TZF A;  3MD7 A;  2Q42 A;  2A7M A;  1YCH A;  2YNV A;  5A0V A;  3JXP A;  3ZR9 A;  2BG8 A;  4Z6X A;  2BC2 A;  5EV8 A;  4TYT A;  3F9O A;  4NQ2 A;  3PY5 A;  3X30 A;  5AEB A;  5KIK A;  5B15 A;  4D1T A;  4AWY B;  4J5F A;  3BV6 A;  4EFZ A;  3RKK A;  1Y44 A;  5HIO A;  4PVO A;  4EY2 A;  2BR6 A;  2BTN A;  2BG6 A;  1QH3 A;  1JT1 A;  3FCZ A;  4C1C A;  4D02 A;  2R2D A;  4C1D A;  5LE1 A;  3X2Z A;  3IOG A;  5LLD A;  1VME A;  3G1P A;  4AX0 B;  2QDS A;  2ZNB A;  4BZ3 A;  1X8I A;  1A8T A;  5K0W A;  4B87 A;  2QIN A;  4AD9 A;  4UAM A;  5ACV A;  1BC2 A;  5K4M A;  3AF5 A;  2YNU A;  1WRA A;  4RL0 A;  2BG7 A;  1BMC A;  2FK6 A;  3IEL A;  4DIL A;  1HLK A;  3FAI A;  3KNS A;  1DXK A;  3X2Y A;  2Q0I A;  3BK2 A;  5ACS A;  2YNT B;  4BP0 A;  3VPE A;  5ACT A;  2BGA A;  4TYF A;  2YNV B;  4WD6 A;  2BIB A;  2OHH A;  4JO0 A;  5ACR A;  5LMC A;  2AZ4 A;  2FU6 A;  3IEK A;  3RPC A;  4RAW A;  2Q9U A;  2BFK A;  5HIS A;  3L6N A;  4RL2 A;  1BVT A;  2E7Y A;  5EWA A;  2FM6 A;  1KR3 A;  5EW0 A;  4F6H A;  4D1V A;  5DPX A;  2HB9 A;  5AXO A;  5HH4 A;  3KNR A;  2WHG A;  2XF4 A;  5B1U A;  2BFZ B;  2WYM A;  3H3E A;  3SPU A;  4AWZ A;  2ZO4 A;  3ZNB A;  2P4Z A;  4LE6 A;  2Y8A A;  2I7X A;  2I7T A;  5AHO A;  5EH9 A;  2QDT A;  4Z67 A;  5ACW A;  5AHR A;  5EV6 A;  4EXS A;  2GCU A;  1DD6 A;  5HH5 A;  3I0V A;  2Q0J A;  5LM6 A;  2OHJ A;  5K4K A;  2WYL A;  2WRS A;  4C1G A;  3DHC A;  3RKJ A;  1VGN A;  5KIL A;  4XWW A;  4TZE A;  4TZ9 A;  1X8H A;  2QED A;  2NZE A;  3VQZ A;  3IOF A;  3A4Y A;  2DKF A;  3DH8 A;  4KEP A;  4GCW A;  5A5Z A;  3BK1 A;  2ZWR A;  4HL2 A;  3ESH A;  3AJ3 A;  2OHI A;  5HIP A;  4HKY A;  2QJS A;  3I14 A;  3SW3 A;  1K07 A;  3DHB A;  1P9E A;  4ZO3 A;  1XTO A;  4FEK A;  1X8G A;  5EVB A;  5IQK A;  3IEM A;  4GYU A;  2BG2 A; 
#chains in the Genus database with same CATH topology
 2FU7 A;  3SD9 A;  2CG2 A;  3ADR A;  4EXY A;  5A23 A;  2P97 A;  2NZF A;  4YSL A;  4U4L A;  2NXA A;  4PVT A;  4C09 A;  4RAM A;  4D1W A;  2CBN A;  4PDX A;  5AYA A;  4UWR B;  1YCF A;  3X2X A;  3T9M A;  2FHX A;  3PY6 A;  4C1H A;  4EYF A;  5LSC A;  1M2X A;  5ACX A;  5ACQ A;  2M5C A;  4Z60 A;  3PG4 A;  4NQ5 A;  4EYB A;  2YZ3 A;  4Z5Y A;  4J5H A;  3ZQ4 A;  4AX1 B;  4ZO2 A;  1KO2 A;  3IE0 A;  4UWO B;  1WUO A;  4NQ4 A;  2Y87 A;  2GMN A;  5FQC A;  4C1F A;  3SBL A;  1KO3 A;  4D1U A;  1WW1 A;  3I13 A;  4Z5Z A;  4AV7 A;  4XUK A;  4XWT A;  2UYX A;  3Q6V A;  2DOO A;  3QH8 A;  2WYM C;  2YNT A;  1E5D A;  5ACU A;  1SML A;  4RM5 A;  5AXR A;  4RBS A;  1XM8 A;  5A87 A;  2NYP A;  3I15 A;  2Y8B A;  4F6Z A;  3IE1 A;  4UWS B;  5LCH A;  3ZWF A;  2M5D A;  3KL7 A;  4TZB A;  4YSK A;  5HIQ A;  2YCB A;  4ZNB A;  2FU8 A;  1DDK A;  2ZZI A;  4EYL A;  2VW8 A;  3SFP A;  5B3R A;  4C1E A;  2GFK A;  4YSB A;  5K4N A;  3SRX A;  2BFL A;  4ZEJ A;  3LVZ A;  1L9Y A;  1JJT A;  3I11 A;  1JJE A;  3IDZ A;  1ZKP A;  4Z7R A;  3IE2 A;  4DIK A;  4HL1 A;  1ZTC A;  4H0D A;  2FU9 A;  5FQB A;  3R2U A;  5EHT A;  4UBQ A;  5AIJ A;  2AIO A;  5HH6 A;  4CHL A;  1WUP A;  2YNW A;  5FQA A;  4FR7 A;  2XR1 A;  1A7T A;  4V0H A;  2GKL A;  1YCG A;  5LCA A;  3WXC A;  5EVD A;  1QH5 A;  4NQ6 A;  3AF6 A;  5EVK A;  3P2U A;  2I7V A;  2BFZ A;  3TP9 A;  4GYQ A;  4P62 A;  4KEQ A;  1VJN A;  3S0Z A;  4O98 A;  1ZNB A;  5ACP A;  2GFJ A;  4UA4 A;  2FHX B;  2P18 A;  2P1E A;  3T3O A;  3BC2 A;  5LCF A;  5A0T A;  4UWP B;  4FSB A;  2BMI A;  2BG8 B;  1MQO A;  2H6A A;  3T3N A;  5LS3 A;  3DHA A;  4TZF A;  3MD7 A;  2Q42 A;  2A7M A;  1YCH A;  2YNV A;  5A0V A;  3JXP A;  3ZR9 A;  2BG8 A;  4Z6X A;  2BC2 A;  5EV8 A;  4TYT A;  3F9O A;  4NQ2 A;  3PY5 A;  3X30 A;  5AEB A;  5KIK A;  5B15 A;  4D1T A;  4AWY B;  4J5F A;  3BV6 A;  4EFZ A;  3RKK A;  1Y44 A;  5HIO A;  4PVO A;  4EY2 A;  2BR6 A;  2BTN A;  2BG6 A;  1QH3 A;  1JT1 A;  3FCZ A;  4C1C A;  2BG2 A;  4D02 A;  2R2D A;  4C1D A;  5LE1 A;  3X2Z A;  3IOG A;  5LLD A;  1VME A;  3G1P A;  4AX0 B;  2CFU A;  2QDS A;  2ZNB A;  4BZ3 A;  1X8I A;  1A8T A;  5K0W A;  4B87 A;  2QIN A;  4AD9 A;  4UAM A;  5ACV A;  1BC2 A;  5K4M A;  2CFZ A;  3AF5 A;  2YNU A;  1WRA A;  4RL0 A;  2BG7 A;  1BMC A;  2FK6 A;  3IEL A;  4DIL A;  1HLK A;  3FAI A;  3KNS A;  1DXK A;  3X2Y A;  2Q0I A;  3BK2 A;  5ACS A;  2YNT B;  4BP0 A;  3VPE A;  5ACT A;  2BGA A;  4TYF A;  2YNV B;  4WD6 A;  2BIB A;  2OHH A;  4JO0 A;  5ACR A;  5LMC A;  2AZ4 A;  2FU6 A;  3IEK A;  3RPC A;  4RAW A;  2Q9U A;  2BFK A;  5HIS A;  3L6N A;  4RL2 A;  1BVT A;  2E7Y A;  5EWA A;  2FM6 A;  1KR3 A;  5EW0 A;  4F6H A;  4D1V A;  5DPX A;  2HB9 A;  4NUR A;  5AXO A;  5HH4 A;  2CG3 A;  3KNR A;  2WHG A;  2XF4 A;  5B1U A;  2BFZ B;  2WYM A;  3H3E A;  3SPU A;  4AWZ A;  2ZO4 A;  3ZNB A;  2P4Z A;  4LE6 A;  2Y8A A;  2I7X A;  2I7T A;  5AHO A;  5EH9 A;  2QDT A;  4Z67 A;  5ACW A;  5AHR A;  5EV6 A;  4EXS A;  2GCU A;  1DD6 A;  5HH5 A;  3I0V A;  2Q0J A;  5LM6 A;  2OHJ A;  5K4K A;  2WYL A;  2WRS A;  4C1G A;  3DHC A;  3RKJ A;  1VGN A;  5KIL A;  4XWW A;  4TZE A;  4TZ9 A;  1X8H A;  2QED A;  2NZE A;  3VQZ A;  3IOF A;  3A4Y A;  2DKF A;  3DH8 A;  4KEP A;  4GCW A;  5A5Z A;  3BK1 A;  2ZWR A;  4HL2 A;  3ESH A;  3AJ3 A;  2OHI A;  5HIP A;  4HKY A;  2QJS A;  3I14 A;  3SW3 A;  1K07 A;  5AJL A;  3DHB A;  1P9E A;  4ZO3 A;  4AXH A;  1XTO A;  4FEK A;  1X8G A;  5EVB A;  5IQK A;  3IEM A;  4GYU A;  2YHE A; 
#chains in the Genus database with same CATH homology
 2FU7 A;  3SD9 A;  3ADR A;  4EXY A;  2P97 A;  2NZF A;  4YSL A;  4U4L A;  2NXA A;  4PVT A;  4C09 A;  4RAM A;  4D1W A;  2CBN A;  5AYA A;  4UWR B;  1YCF A;  3X2X A;  3T9M A;  2FHX A;  3PY6 A;  4C1H A;  4EYF A;  5LSC A;  1M2X A;  5ACX A;  5ACQ A;  2M5C A;  4Z60 A;  3PG4 A;  4NQ5 A;  4EYB A;  2YZ3 A;  4Z5Y A;  4J5H A;  3ZQ4 A;  4AX1 B;  4ZO2 A;  1KO2 A;  3IE0 A;  4UWO B;  1WUO A;  4NQ4 A;  2Y87 A;  2GMN A;  5FQC A;  4C1F A;  3SBL A;  1KO3 A;  4D1U A;  1WW1 A;  3I13 A;  4Z5Z A;  4XUK A;  4XWT A;  2UYX A;  3Q6V A;  2DOO A;  3QH8 A;  2WYM C;  2YNT A;  1E5D A;  5ACU A;  1SML A;  4RM5 A;  5AXR A;  4RBS A;  1XM8 A;  5A87 A;  2NYP A;  3I15 A;  2Y8B A;  4F6Z A;  3IE1 A;  4UWS B;  5LCH A;  3ZWF A;  2M5D A;  3KL7 A;  4TZB A;  4YSK A;  5HIQ A;  2YCB A;  4ZNB A;  2FU8 A;  1DDK A;  2ZZI A;  4EYL A;  2VW8 A;  3SFP A;  5B3R A;  4C1E A;  2GFK A;  4YSB A;  5K4N A;  3SRX A;  2BFL A;  4ZEJ A;  3LVZ A;  1L9Y A;  1JJT A;  3I11 A;  1JJE A;  3IDZ A;  1ZKP A;  4Z7R A;  3IE2 A;  4DIK A;  4HL1 A;  1ZTC A;  4H0D A;  2FU9 A;  5FQB A;  3R2U A;  5EHT A;  4UBQ A;  2AIO A;  5HH6 A;  4CHL A;  1WUP A;  2YNW A;  5FQA A;  4FR7 A;  2XR1 A;  1A7T A;  4V0H A;  1YCG A;  2GKL A;  5LCA A;  3WXC A;  5EVD A;  1QH5 A;  4NQ6 A;  3AF6 A;  5EVK A;  3P2U A;  2I7V A;  2BFZ A;  3TP9 A;  4GYQ A;  4P62 A;  4KEQ A;  1VJN A;  3S0Z A;  4O98 A;  1ZNB A;  5ACP A;  2GFJ A;  4UA4 A;  2FHX B;  2P18 A;  2P1E A;  3T3O A;  3BC2 A;  5LCF A;  5A0T A;  4UWP B;  4FSB A;  2BMI A;  2BG8 B;  1MQO A;  2H6A A;  3T3N A;  5LS3 A;  3DHA A;  4TZF A;  3MD7 A;  2Q42 A;  2A7M A;  1YCH A;  2YNV A;  5A0V A;  3JXP A;  3ZR9 A;  2BG8 A;  4Z6X A;  2BC2 A;  5EV8 A;  4TYT A;  3F9O A;  4NQ2 A;  3PY5 A;  3X30 A;  5AEB A;  5KIK A;  5B15 A;  4D1T A;  4AWY B;  4J5F A;  3BV6 A;  4EFZ A;  3RKK A;  1Y44 A;  5HIO A;  4PVO A;  4EY2 A;  2BR6 A;  2BTN A;  2BG6 A;  1QH3 A;  1JT1 A;  3FCZ A;  4C1C A;  4D02 A;  2R2D A;  4C1D A;  5LE1 A;  3X2Z A;  3IOG A;  5LLD A;  1VME A;  3G1P A;  4AX0 B;  2QDS A;  2ZNB A;  4BZ3 A;  1X8I A;  1A8T A;  5K0W A;  4B87 A;  2QIN A;  4AD9 A;  4UAM A;  5ACV A;  1BC2 A;  5K4M A;  3AF5 A;  2YNU A;  1WRA A;  4RL0 A;  2BG7 A;  1BMC A;  2FK6 A;  3IEL A;  4DIL A;  1HLK A;  3FAI A;  3KNS A;  1DXK A;  3X2Y A;  2Q0I A;  3BK2 A;  5ACS A;  2YNT B;  4BP0 A;  3VPE A;  5ACT A;  2BGA A;  4TYF A;  2YNV B;  4WD6 A;  2BIB A;  2OHH A;  4JO0 A;  5ACR A;  5LMC A;  2AZ4 A;  2FU6 A;  3IEK A;  3RPC A;  4RAW A;  2Q9U A;  2BFK A;  5HIS A;  3L6N A;  4RL2 A;  1BVT A;  2E7Y A;  5EWA A;  2FM6 A;  1KR3 A;  5EW0 A;  4F6H A;  4D1V A;  5DPX A;  2HB9 A;  5AXO A;  5HH4 A;  3KNR A;  2WHG A;  2XF4 A;  5B1U A;  2BFZ B;  2WYM A;  3H3E A;  3SPU A;  4AWZ A;  2ZO4 A;  3ZNB A;  2P4Z A;  4LE6 A;  2Y8A A;  2I7X A;  2I7T A;  5AHO A;  5EH9 A;  2QDT A;  4Z67 A;  5ACW A;  5AHR A;  5EV6 A;  4EXS A;  2GCU A;  1DD6 A;  5HH5 A;  3I0V A;  2Q0J A;  5LM6 A;  2OHJ A;  5K4K A;  2WYL A;  2WRS A;  4C1G A;  3DHC A;  3RKJ A;  1VGN A;  5KIL A;  4XWW A;  4TZE A;  4TZ9 A;  1X8H A;  2QED A;  2NZE A;  3VQZ A;  3IOF A;  3A4Y A;  2DKF A;  3DH8 A;  4KEP A;  4GCW A;  5A5Z A;  3BK1 A;  2ZWR A;  4HL2 A;  3ESH A;  3AJ3 A;  2OHI A;  5HIP A;  4HKY A;  2QJS A;  3I14 A;  3SW3 A;  1K07 A;  3DHB A;  1P9E A;  4ZO3 A;  1XTO A;  4FEK A;  1X8G A;  5EVB A;  5IQK A;  3IEM A;  4GYU A;  2BG2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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