5K4KA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-4
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
228
structure length
228
Chain Sequence
DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Metallo-beta-lactamase type 2
publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
source organism Klebsiella pneumoniae
molecule tags Hydrolase
total genus 70
structure length 228
sequence length 228
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-05-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4kA00
3I15A 3G1PA 5EWAA 1L9YA 5LCHA 5AHOA 4NQ5A 1QH5A 4C1EA 2BG7A 5K0WA 5LLDA 3IE1A 1QH3A 2I7XA 1XTOA 5ACTA 5HH4A 3IOFA 3QH8A 1X8IA 5ACUA 3RKJA 1ZTCA 1BVTA 1A7TA 2BG6A 5HIPA 2DKFA 2YNTA 2I7VA 4HL1A 4D1WA 2FU8A 2P97A 1A8TA 3IEMA 2GCUA 3LVZA 3AF5A 3AJ3A 4UWOB 5AXRA 4TZEA 5K4NA 2FM6A 3BC2A 4Z6XA 4PVTA 2I7TA 3ZR9A 2BMIA 2QEDA 4Z7RA 5K4KA 1DD6A 3VPEA 2AZ4A 4EXYA 4ZNBA 3H3EA 4UA4A 1WRAA 3IE2A 4NQ6A 2BC2A 5LCAA 3Q6VA 5A5ZA 1X8GA 2M5CA 4D1UA 4Z5ZA 5LS3A 5A87A 3X2XA 2GMNA 3P2UA 5HH6A 2YNUA 4F6ZA 5HIQA 4C1FA 3KL7A 2QJSA 1KR3A 1Y44A 4RBSA 5HIOA 3RKKA 2Q42A 4U4LA 5ACVA 4C1GA 4AX1B 4TZFA 2ZZIA 3X30A 5ACWA 4Z67A 5AYAA 1JJEA 5A0VA 4D02A 1ZNBA 4EYBA 4XWWA 4EYLA 4F6HA 4Z5YA 2AIOA 5A0TA 2FU7A 4C1CA 2BR6A 2QDSA 2E7YA 4JO0A 2OHHA 1DXKA 2BIBA 4CHLA 4PVOA 3S0ZA 4Z60A 2ZNBA 4ZO3A 1DDKA 3A4YA 4TYTA 2ZWRA 1X8HA 2BFZA 3IOGA 2CBNA 4BP0A 2BGAA 3SPUA 4AWZA 2ZO4A 2BTNA 5B1UA 4AX0B 4DIKA 3JXPA 3WXCA 2FU9A 3T9MA 4GYQA 4J5HA 4EFZA 4GYUA 2Q0JA 3SFPA 1YCFA 4C1HA 3IDZA 2Q9UA 2OHJA 3DH8A 3KNSA 4H0DA 2XR1A 5EV8A 5KIKA 5ACPA 3AF6A 1SMLA 3X2YA 2FHXB 4UBQA 4XUKA 3KNRA 2P1EA 3PG4A 2GKLA 4YSLA 3ESHA 5B3RA 1WW1A 1WUPA 3PY5A 4UWPB 4D1VA 1BMCA 3DHBA 1ZKPA 2YCBA 4TZ9A 1P9EA 2NYPA 3BK2A 4RL0A 5FQBA 2GFJA 4B87A 4AD9A 3FAIA 3FCZA 5AXOA 3DHCA 4C1DA 3I14A 3ZWFA 2WHGA 4EY2A 1K07A 2GFKA 2VW8A 4HL2A 1YCHA 2FHXA 5EH9A 3X2ZA 4EXSA 2YZ3A 3MD7A 2H6AA 3VQZA 3ADRA 4V0HA 2M5DA 1M2XA 4UWSB 2Q0IA 1WUOA 2QINA 4LE6A 2UYXA 1VMEA 4FR7A 5DPXA 2QDTA 2WYLA 2R2DA 3T3OA 5LCFA 3IELA 3PY6A 1HLKA 3SW3A 1KO3A 4RM5A 5LSCA 4BZ3A 2BFLA 5FQAA 3I0VA 4UAMA 2Y87A 2BG2A 4RAWA 4XWTA 4NQ2A 4YSBA 5EVDA 5EVKA 2Y8AA 2YNVB 3I13A 5LE1A 2NXAA 4RL2A 5K4MA 3ZNBA 2WYMA 4J5FA 3SRXA 2BG8B 5EW0A 4EYFA 3R2UA 1BC2A 1VGNA 1XM8A 3IEKA 4ZO2A 4D1TA 3IE0A 2WRSA 4YSKA 4O98A 4KEPA 4WD6A 3SBLA 5HISA 4UWRB 2P18A 1YCGA 5ACRA 4FEKA 5B15A 5IQKA 2XF4A 3DHAA 3SD9A 2OHIA 4C09A 4AWYB 2A7MA 5EHTA 2Y8BA 5LM6A 3L6NA 2DOOA 5ACXA 2YNWA 2YNVA 4KEQA 2NZFA 1E5DA 1KO2A 5ACSA 5EV6A 4RAMA 4HKYA 4TYFA 2BG8A 4NQ4A 4ZEJA 3I11A 5AEBA 3BK1A 5ACQA 2P4ZA 5KILA 3RPCA 1MQOA 5AHRA 5FQCA 2BFZB 2NZEA 3F9OA 5LMCA 4FSBA 1JT1A 5HH5A 2FK6A 2WYMC 2HB9A 3T3NA 2YNTB 3BV6A 4P62A 1JJTA 4TZBA 2BFKA 2FU6A 4GCWA 3TP9A 1VJNA 3ZQ4A 5EVBA 4DILA
chains in the Genus database with same CATH superfamily
3I15A 3G1PA 5EWAA 1L9YA 5LCHA 5AHOA 4NQ5A 1QH5A 4C1EA 2BG7A 5K0WA 5LLDA 3IE1A 1QH3A 2I7XA 1XTOA 5ACTA 5HH4A 3IOFA 3QH8A 1X8IA 5ACUA 3RKJA 1ZTCA 2CFUA 1BVTA 1A7TA 2BG6A 5HIPA 2DKFA 2YNTA 2I7VA 4HL1A 4D1WA 2FU8A 2P97A 1A8TA 3IEMA 2GCUA 3LVZA 3AF5A 3AJ3A 4UWOB 5AXRA 4TZEA 5K4NA 4PDXA 2FM6A 3BC2A 4Z6XA 4PVTA 2I7TA 3ZR9A 2BMIA 2QEDA 4Z7RA 5K4KA 1DD6A 3VPEA 2AZ4A 4EXYA 4ZNBA 3H3EA 4UA4A 1WRAA 2YHEA 3IE2A 4AXHA 4NQ6A 2BC2A 5LCAA 3Q6VA 5A5ZA 1X8GA 2M5CA 4D1UA 4Z5ZA 5LS3A 5A87A 3X2XA 2GMNA 3P2UA 5HH6A 2YNUA 4F6ZA 5HIQA 4C1FA 3KL7A 2QJSA 1KR3A 1Y44A 4RBSA 5HIOA 3RKKA 2Q42A 4U4LA 5ACVA 4C1GA 4AX1B 4TZFA 2ZZIA 3X30A 5ACWA 4Z67A 5AYAA 1JJEA 5A0VA 4D02A 1ZNBA 4EYBA 4XWWA 4EYLA 4F6HA 4Z5YA 2AIOA 5A0TA 2FU7A 4C1CA 2BR6A 2QDSA 2E7YA 4JO0A 2OHHA 1DXKA 2BIBA 4CHLA 4PVOA 3S0ZA 4Z60A 2ZNBA 4ZO3A 1DDKA 3A4YA 4TYTA 2ZWRA 1X8HA 2BFZA 3IOGA 2CBNA 4BP0A 2BGAA 3SPUA 4AWZA 2ZO4A 2BTNA 5B1UA 4AX0B 4DIKA 3JXPA 3WXCA 2FU9A 3T9MA 4GYQA 4J5HA 4EFZA 4GYUA 2Q0JA 3SFPA 1YCFA 4C1HA 3IDZA 2Q9UA 2OHJA 3DH8A 3KNSA 4H0DA 2XR1A 5EV8A 5KIKA 5ACPA 3AF6A 2CG2A 1SMLA 3X2YA 2FHXB 4UBQA 4XUKA 3KNRA 5AJLA 2P1EA 3PG4A 2GKLA 4YSLA 3ESHA 5B3RA 1WW1A 1WUPA 4NURA 3PY5A 4UWPB 4D1VA 1BMCA 4AV7A 3DHBA 1ZKPA 2YCBA 4TZ9A 1P9EA 2NYPA 3BK2A 4RL0A 5FQBA 2GFJA 4B87A 4AD9A 3FAIA 3FCZA 5AXOA 3DHCA 4C1DA 3I14A 3ZWFA 2WHGA 4EY2A 1K07A 2GFKA 2VW8A 4HL2A 1YCHA 2FHXA 5EH9A 3X2ZA 4EXSA 2YZ3A 3MD7A 2H6AA 3VQZA 3ADRA 4V0HA 2M5DA 1M2XA 4UWSB 5A23A 2Q0IA 1WUOA 2QINA 4LE6A 2UYXA 1VMEA 4FR7A 5DPXA 2QDTA 2WYLA 2R2DA 3T3OA 5LCFA 3IELA 3PY6A 1HLKA 3SW3A 1KO3A 4RM5A 5LSCA 4BZ3A 2BFLA 5FQAA 3I0VA 4UAMA 2Y87A 2BG2A 4RAWA 4XWTA 4NQ2A 4YSBA 5EVDA 5EVKA 2Y8AA 2YNVB 3I13A 5LE1A 2NXAA 4RL2A 5K4MA 3ZNBA 2WYMA 4J5FA 3SRXA 2BG8B 5EW0A 4EYFA 3R2UA 1BC2A 1VGNA 1XM8A 3IEKA 4ZO2A 2CFZA 4D1TA 3IE0A 5AIJA 2WRSA 4YSKA 4O98A 4KEPA 4WD6A 3SBLA 5HISA 4UWRB 2P18A 1YCGA 5ACRA 4FEKA 2CG3A 5B15A 5IQKA 2XF4A 3DHAA 3SD9A 2OHIA 4C09A 4AWYB 2A7MA 5EHTA 2Y8BA 5LM6A 3L6NA 2DOOA 5ACXA 2YNWA 2YNVA 4KEQA 2NZFA 1E5DA 1KO2A 5ACSA 5EV6A 4RAMA 4HKYA 4TYFA 2BG8A 4NQ4A 4ZEJA 3I11A 5AEBA 3BK1A 5ACQA 2P4ZA 5KILA 3RPCA 1MQOA 5AHRA 5FQCA 2BFZB 2NZEA 3F9OA 5LMCA 4FSBA 1JT1A 5HH5A 2FK6A 2WYMC 2HB9A 3T3NA 2YNTB 3BV6A 4P62A 1JJTA 4TZBA 2BFKA 2FU6A 4GCWA 3TP9A 1VJNA 3ZQ4A 5EVBA 4DILA
chains in the Genus database with same CATH topology
3I15A 3G1PA 5EWAA 1L9YA 5LCHA 5AHOA 4NQ5A 1QH5A 4C1EA 2BG7A 5K0WA 5LLDA 3IE1A 1QH3A 2I7XA 1XTOA 5ACTA 5HH4A 3IOFA 3QH8A 1X8IA 5ACUA 3RKJA 1ZTCA 1BVTA 1A7TA 2BG6A 5HIPA 2DKFA 2YNTA 2I7VA 4HL1A 4D1WA 2FU8A 2P97A 1A8TA 3IEMA 2GCUA 3LVZA 3AF5A 3AJ3A 4UWOB 5AXRA 4TZEA 5K4NA 2FM6A 3BC2A 4Z6XA 4PVTA 2I7TA 3ZR9A 2BMIA 2QEDA 4Z7RA 5K4KA 1DD6A 3VPEA 2AZ4A 4EXYA 4ZNBA 3H3EA 4UA4A 1WRAA 3IE2A 4NQ6A 2BC2A 5LCAA 3Q6VA 5A5ZA 1X8GA 2M5CA 4D1UA 4Z5ZA 5LS3A 5A87A 3X2XA 2GMNA 3P2UA 5HH6A 2YNUA 4F6ZA 5HIQA 4C1FA 3KL7A 2QJSA 1KR3A 1Y44A 4RBSA 5HIOA 3RKKA 2Q42A 4U4LA 5ACVA 4C1GA 4AX1B 4TZFA 2ZZIA 3X30A 5ACWA 4Z67A 5AYAA 1JJEA 5A0VA 4D02A 1ZNBA 4EYBA 4XWWA 4EYLA 4F6HA 4Z5YA 2AIOA 5A0TA 2FU7A 4C1CA 2BR6A 2QDSA 2E7YA 4JO0A 2OHHA 1DXKA 2BIBA 4CHLA 4PVOA 3S0ZA 4Z60A 2ZNBA 4ZO3A 1DDKA 3A4YA 4TYTA 2ZWRA 1X8HA 2BFZA 3IOGA 2CBNA 4BP0A 2BGAA 3SPUA 4AWZA 2ZO4A 2BTNA 5B1UA 4AX0B 4DIKA 3JXPA 3WXCA 2FU9A 3T9MA 4GYQA 4J5HA 4EFZA 4GYUA 2Q0JA 3SFPA 1YCFA 4C1HA 3IDZA 2Q9UA 2OHJA 3DH8A 3KNSA 4H0DA 2XR1A 5EV8A 5KIKA 5ACPA 3AF6A 1SMLA 3X2YA 2FHXB 4UBQA 4XUKA 3KNRA 2P1EA 3PG4A 2GKLA 4YSLA 3ESHA 5B3RA 1WW1A 1WUPA 3PY5A 4UWPB 4D1VA 1BMCA 3DHBA 1ZKPA 2YCBA 4TZ9A 1P9EA 2NYPA 3BK2A 4RL0A 5FQBA 2GFJA 4B87A 4AD9A 3FAIA 3FCZA 5AXOA 3DHCA 4C1DA 3I14A 3ZWFA 2WHGA 4EY2A 1K07A 2GFKA 2VW8A 4HL2A 1YCHA 2FHXA 5EH9A 3X2ZA 4EXSA 2YZ3A 3MD7A 2H6AA 3VQZA 3ADRA 4V0HA 2M5DA 1M2XA 4UWSB 2Q0IA 1WUOA 2QINA 4LE6A 2UYXA 1VMEA 4FR7A 5DPXA 2QDTA 2WYLA 2R2DA 3T3OA 5LCFA 3IELA 3PY6A 1HLKA 3SW3A 1KO3A 4RM5A 5LSCA 4BZ3A 2BFLA 5FQAA 3I0VA 4UAMA 2Y87A 2BG2A 4RAWA 4XWTA 4NQ2A 4YSBA 5EVDA 5EVKA 2Y8AA 2YNVB 3I13A 5LE1A 2NXAA 4RL2A 5K4MA 3ZNBA 2WYMA 4J5FA 3SRXA 2BG8B 5EW0A 4EYFA 3R2UA 1BC2A 1VGNA 1XM8A 3IEKA 4ZO2A 4D1TA 3IE0A 2WRSA 4YSKA 4O98A 4KEPA 4WD6A 3SBLA 5HISA 4UWRB 2P18A 1YCGA 5ACRA 4FEKA 5B15A 5IQKA 2XF4A 3DHAA 3SD9A 2OHIA 4C09A 4AWYB 2A7MA 5EHTA 2Y8BA 5LM6A 3L6NA 2DOOA 5ACXA 2YNWA 2YNVA 4KEQA 2NZFA 1E5DA 1KO2A 5ACSA 5EV6A 4RAMA 4HKYA 4TYFA 2BG8A 4NQ4A 4ZEJA 3I11A 5AEBA 3BK1A 5ACQA 2P4ZA 5KILA 3RPCA 1MQOA 5AHRA 5FQCA 2BFZB 2NZEA 3F9OA 5LMCA 4FSBA 1JT1A 5HH5A 2FK6A 2WYMC 2HB9A 3T3NA 2YNTB 3BV6A 4P62A 1JJTA 4TZBA 2BFKA 2FU6A 4GCWA 3TP9A 1VJNA 3ZQ4A 5EVBA 4DILA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I15 A;  3G1P A;  5EWA A;  1L9Y A;  5LCH A;  5AHO A;  4NQ5 A;  1QH5 A;  4C1E A;  2BG7 A;  5K0W A;  5LLD A;  3IE1 A;  1QH3 A;  2I7X A;  1XTO A;  5ACT A;  5HH4 A;  3IOF A;  3QH8 A;  1X8I A;  5ACU A;  3RKJ A;  1ZTC A;  1BVT A;  1A7T A;  2BG6 A;  5HIP A;  2DKF A;  2YNT A;  2I7V A;  4HL1 A;  4D1W A;  2FU8 A;  2P97 A;  1A8T A;  3IEM A;  2GCU A;  3LVZ A;  3AF5 A;  3AJ3 A;  4UWO B;  5AXR A;  4TZE A;  5K4N A;  2FM6 A;  3BC2 A;  4Z6X A;  4PVT A;  2I7T A;  3ZR9 A;  2BMI A;  2QED A;  4Z7R A;  5K4K A;  1DD6 A;  3VPE A;  2AZ4 A;  4EXY A;  4ZNB A;  3H3E A;  4UA4 A;  1WRA A;  3IE2 A;  4NQ6 A;  2BC2 A;  5LCA A;  3Q6V A;  5A5Z A;  1X8G A;  2M5C A;  4D1U A;  4Z5Z A;  5LS3 A;  5A87 A;  3X2X A;  2GMN A;  3P2U A;  5HH6 A;  2YNU A;  4F6Z A;  5HIQ A;  4C1F A;  3KL7 A;  2QJS A;  1KR3 A;  1Y44 A;  4RBS A;  5HIO A;  3RKK A;  2Q42 A;  4U4L A;  5ACV A;  4C1G A;  4AX1 B;  4TZF A;  2ZZI A;  3X30 A;  5ACW A;  4Z67 A;  5AYA A;  1JJE A;  5A0V A;  4D02 A;  1ZNB A;  4EYB A;  4XWW A;  4EYL A;  4F6H A;  4Z5Y A;  2AIO A;  5A0T A;  2FU7 A;  4C1C A;  2BR6 A;  2QDS A;  2E7Y A;  4JO0 A;  2OHH A;  1DXK A;  2BIB A;  4CHL A;  4PVO A;  3S0Z A;  4Z60 A;  2ZNB A;  4ZO3 A;  1DDK A;  3A4Y A;  4TYT A;  2ZWR A;  1X8H A;  2BFZ A;  3IOG A;  2CBN A;  4BP0 A;  2BGA A;  3SPU A;  4AWZ A;  2ZO4 A;  2BTN A;  5B1U A;  4AX0 B;  4DIK A;  3JXP A;  3WXC A;  2FU9 A;  3T9M A;  4GYQ A;  4J5H A;  4EFZ A;  4GYU A;  2Q0J A;  3SFP A;  1YCF A;  4C1H A;  3IDZ A;  2Q9U A;  2OHJ A;  3DH8 A;  3KNS A;  4H0D A;  2XR1 A;  5EV8 A;  5KIK A;  5ACP A;  3AF6 A;  1SML A;  3X2Y A;  2FHX B;  4UBQ A;  4XUK A;  3KNR A;  2P1E A;  3PG4 A;  2GKL A;  4YSL A;  3ESH A;  5B3R A;  1WW1 A;  1WUP A;  3PY5 A;  4UWP B;  4D1V A;  1BMC A;  3DHB A;  1ZKP A;  2YCB A;  4TZ9 A;  1P9E A;  2NYP A;  3BK2 A;  4RL0 A;  5FQB A;  2GFJ A;  4B87 A;  4AD9 A;  3FAI A;  3FCZ A;  5AXO A;  3DHC A;  4C1D A;  3I14 A;  3ZWF A;  2WHG A;  4EY2 A;  1K07 A;  2GFK A;  2VW8 A;  4HL2 A;  1YCH A;  2FHX A;  5EH9 A;  3X2Z A;  4EXS A;  2YZ3 A;  3MD7 A;  2H6A A;  3VQZ A;  3ADR A;  4V0H A;  2M5D A;  1M2X A;  4UWS B;  2Q0I A;  1WUO A;  2QIN A;  4LE6 A;  2UYX A;  1VME A;  4FR7 A;  5DPX A;  2QDT A;  2WYL A;  2R2D A;  3T3O A;  5LCF A;  3IEL A;  3PY6 A;  1HLK A;  3SW3 A;  1KO3 A;  4RM5 A;  5LSC A;  4BZ3 A;  2BFL A;  5FQA A;  3I0V A;  4UAM A;  2Y87 A;  2BG2 A;  4RAW A;  4XWT A;  4NQ2 A;  4YSB A;  5EVD A;  5EVK A;  2Y8A A;  2YNV B;  3I13 A;  5LE1 A;  2NXA A;  4RL2 A;  5K4M A;  3ZNB A;  2WYM A;  4J5F A;  3SRX A;  2BG8 B;  5EW0 A;  4EYF A;  3R2U A;  1BC2 A;  1VGN A;  1XM8 A;  3IEK A;  4ZO2 A;  4D1T A;  3IE0 A;  2WRS A;  4YSK A;  4O98 A;  4KEP A;  4WD6 A;  3SBL A;  5HIS A;  4UWR B;  2P18 A;  1YCG A;  5ACR A;  4FEK A;  5B15 A;  5IQK A;  2XF4 A;  3DHA A;  3SD9 A;  2OHI A;  4C09 A;  4AWY B;  2A7M A;  5EHT A;  2Y8B A;  5LM6 A;  3L6N A;  2DOO A;  5ACX A;  2YNW A;  2YNV A;  4KEQ A;  2NZF A;  1E5D A;  1KO2 A;  5ACS A;  5EV6 A;  4RAM A;  4HKY A;  4TYF A;  2BG8 A;  4NQ4 A;  4ZEJ A;  3I11 A;  5AEB A;  3BK1 A;  5ACQ A;  2P4Z A;  5KIL A;  3RPC A;  1MQO A;  5AHR A;  5FQC A;  2BFZ B;  2NZE A;  3F9O A;  5LMC A;  4FSB A;  1JT1 A;  5HH5 A;  2FK6 A;  2WYM C;  2HB9 A;  3T3N A;  2YNT B;  3BV6 A;  4P62 A;  1JJT A;  4TZB A;  2BFK A;  2FU6 A;  4GCW A;  3TP9 A;  1VJN A;  3ZQ4 A;  5EVB A;  4DIL A; 
#chains in the Genus database with same CATH topology
 3I15 A;  3G1P A;  5EWA A;  1L9Y A;  5LCH A;  5AHO A;  4NQ5 A;  1QH5 A;  4C1E A;  2BG7 A;  5K0W A;  5LLD A;  3IE1 A;  1QH3 A;  2I7X A;  1XTO A;  5ACT A;  5HH4 A;  3IOF A;  3QH8 A;  1X8I A;  5ACU A;  3RKJ A;  1ZTC A;  2CFU A;  1BVT A;  1A7T A;  2BG6 A;  5HIP A;  2DKF A;  2YNT A;  2I7V A;  4HL1 A;  4D1W A;  2FU8 A;  2P97 A;  1A8T A;  3IEM A;  2GCU A;  3LVZ A;  3AF5 A;  3AJ3 A;  4UWO B;  5AXR A;  4TZE A;  5K4N A;  4PDX A;  2FM6 A;  3BC2 A;  4Z6X A;  4PVT A;  2I7T A;  3ZR9 A;  2BMI A;  2QED A;  4Z7R A;  5K4K A;  1DD6 A;  3VPE A;  2AZ4 A;  4EXY A;  4ZNB A;  3H3E A;  4UA4 A;  1WRA A;  2YHE A;  3IE2 A;  4AXH A;  4NQ6 A;  2BC2 A;  5LCA A;  3Q6V A;  5A5Z A;  1X8G A;  2M5C A;  4D1U A;  4Z5Z A;  5LS3 A;  5A87 A;  3X2X A;  2GMN A;  3P2U A;  5HH6 A;  2YNU A;  4F6Z A;  5HIQ A;  4C1F A;  3KL7 A;  2QJS A;  1KR3 A;  1Y44 A;  4RBS A;  5HIO A;  3RKK A;  2Q42 A;  4U4L A;  5ACV A;  4C1G A;  4AX1 B;  4TZF A;  2ZZI A;  3X30 A;  5ACW A;  4Z67 A;  5AYA A;  1JJE A;  5A0V A;  4D02 A;  1ZNB A;  4EYB A;  4XWW A;  4EYL A;  4F6H A;  4Z5Y A;  2AIO A;  5A0T A;  2FU7 A;  4C1C A;  2BR6 A;  2QDS A;  2E7Y A;  4JO0 A;  2OHH A;  1DXK A;  2BIB A;  4CHL A;  4PVO A;  3S0Z A;  4Z60 A;  2ZNB A;  4ZO3 A;  1DDK A;  3A4Y A;  4TYT A;  2ZWR A;  1X8H A;  2BFZ A;  3IOG A;  2CBN A;  4BP0 A;  2BGA A;  3SPU A;  4AWZ A;  2ZO4 A;  2BTN A;  5B1U A;  4AX0 B;  4DIK A;  3JXP A;  3WXC A;  2FU9 A;  3T9M A;  4GYQ A;  4J5H A;  4EFZ A;  4GYU A;  2Q0J A;  3SFP A;  1YCF A;  4C1H A;  3IDZ A;  2Q9U A;  2OHJ A;  3DH8 A;  3KNS A;  4H0D A;  2XR1 A;  5EV8 A;  5KIK A;  5ACP A;  3AF6 A;  2CG2 A;  1SML A;  3X2Y A;  2FHX B;  4UBQ A;  4XUK A;  3KNR A;  5AJL A;  2P1E A;  3PG4 A;  2GKL A;  4YSL A;  3ESH A;  5B3R A;  1WW1 A;  1WUP A;  4NUR A;  3PY5 A;  4UWP B;  4D1V A;  1BMC A;  4AV7 A;  3DHB A;  1ZKP A;  2YCB A;  4TZ9 A;  1P9E A;  2NYP A;  3BK2 A;  4RL0 A;  5FQB A;  2GFJ A;  4B87 A;  4AD9 A;  3FAI A;  3FCZ A;  5AXO A;  3DHC A;  4C1D A;  3I14 A;  3ZWF A;  2WHG A;  4EY2 A;  1K07 A;  2GFK A;  2VW8 A;  4HL2 A;  1YCH A;  2FHX A;  5EH9 A;  3X2Z A;  4EXS A;  2YZ3 A;  3MD7 A;  2H6A A;  3VQZ A;  3ADR A;  4V0H A;  2M5D A;  1M2X A;  4UWS B;  5A23 A;  2Q0I A;  1WUO A;  2QIN A;  4LE6 A;  2UYX A;  1VME A;  4FR7 A;  5DPX A;  2QDT A;  2WYL A;  2R2D A;  3T3O A;  5LCF A;  3IEL A;  3PY6 A;  1HLK A;  3SW3 A;  1KO3 A;  4RM5 A;  5LSC A;  4BZ3 A;  2BFL A;  5FQA A;  3I0V A;  4UAM A;  2Y87 A;  2BG2 A;  4RAW A;  4XWT A;  4NQ2 A;  4YSB A;  5EVD A;  5EVK A;  2Y8A A;  2YNV B;  3I13 A;  5LE1 A;  2NXA A;  4RL2 A;  5K4M A;  3ZNB A;  2WYM A;  4J5F A;  3SRX A;  2BG8 B;  5EW0 A;  4EYF A;  3R2U A;  1BC2 A;  1VGN A;  1XM8 A;  3IEK A;  4ZO2 A;  2CFZ A;  4D1T A;  3IE0 A;  5AIJ A;  2WRS A;  4YSK A;  4O98 A;  4KEP A;  4WD6 A;  3SBL A;  5HIS A;  4UWR B;  2P18 A;  1YCG A;  5ACR A;  4FEK A;  2CG3 A;  5B15 A;  5IQK A;  2XF4 A;  3DHA A;  3SD9 A;  2OHI A;  4C09 A;  4AWY B;  2A7M A;  5EHT A;  2Y8B A;  5LM6 A;  3L6N A;  2DOO A;  5ACX A;  2YNW A;  2YNV A;  4KEQ A;  2NZF A;  1E5D A;  1KO2 A;  5ACS A;  5EV6 A;  4RAM A;  4HKY A;  4TYF A;  2BG8 A;  4NQ4 A;  4ZEJ A;  3I11 A;  5AEB A;  3BK1 A;  5ACQ A;  2P4Z A;  5KIL A;  3RPC A;  1MQO A;  5AHR A;  5FQC A;  2BFZ B;  2NZE A;  3F9O A;  5LMC A;  4FSB A;  1JT1 A;  5HH5 A;  2FK6 A;  2WYM C;  2HB9 A;  3T3N A;  2YNT B;  3BV6 A;  4P62 A;  1JJT A;  4TZB A;  2BFK A;  2FU6 A;  4GCW A;  3TP9 A;  1VJN A;  3ZQ4 A;  5EVB A;  4DIL A; 
#chains in the Genus database with same CATH homology
 3I15 A;  3G1P A;  5EWA A;  1L9Y A;  5LCH A;  5AHO A;  4NQ5 A;  1QH5 A;  4C1E A;  2BG7 A;  5K0W A;  5LLD A;  3IE1 A;  1QH3 A;  2I7X A;  1XTO A;  5ACT A;  5HH4 A;  3IOF A;  3QH8 A;  1X8I A;  5ACU A;  3RKJ A;  1ZTC A;  1BVT A;  1A7T A;  2BG6 A;  5HIP A;  2DKF A;  2YNT A;  2I7V A;  4HL1 A;  4D1W A;  2FU8 A;  2P97 A;  1A8T A;  3IEM A;  2GCU A;  3LVZ A;  3AF5 A;  3AJ3 A;  4UWO B;  5AXR A;  4TZE A;  5K4N A;  2FM6 A;  3BC2 A;  4Z6X A;  4PVT A;  2I7T A;  3ZR9 A;  2BMI A;  2QED A;  4Z7R A;  5K4K A;  1DD6 A;  3VPE A;  2AZ4 A;  4EXY A;  4ZNB A;  3H3E A;  4UA4 A;  1WRA A;  3IE2 A;  4NQ6 A;  2BC2 A;  5LCA A;  3Q6V A;  5A5Z A;  1X8G A;  2M5C A;  4D1U A;  4Z5Z A;  5LS3 A;  5A87 A;  3X2X A;  2GMN A;  3P2U A;  5HH6 A;  2YNU A;  4F6Z A;  5HIQ A;  4C1F A;  3KL7 A;  2QJS A;  1KR3 A;  1Y44 A;  4RBS A;  5HIO A;  3RKK A;  2Q42 A;  4U4L A;  5ACV A;  4C1G A;  4AX1 B;  4TZF A;  2ZZI A;  3X30 A;  5ACW A;  4Z67 A;  5AYA A;  1JJE A;  5A0V A;  4D02 A;  1ZNB A;  4EYB A;  4XWW A;  4EYL A;  4F6H A;  4Z5Y A;  2AIO A;  5A0T A;  2FU7 A;  4C1C A;  2BR6 A;  2QDS A;  2E7Y A;  4JO0 A;  2OHH A;  1DXK A;  2BIB A;  4CHL A;  4PVO A;  3S0Z A;  4Z60 A;  2ZNB A;  4ZO3 A;  1DDK A;  3A4Y A;  4TYT A;  2ZWR A;  1X8H A;  2BFZ A;  3IOG A;  2CBN A;  4BP0 A;  2BGA A;  3SPU A;  4AWZ A;  2ZO4 A;  2BTN A;  5B1U A;  4AX0 B;  4DIK A;  3JXP A;  3WXC A;  2FU9 A;  3T9M A;  4GYQ A;  4J5H A;  4EFZ A;  4GYU A;  2Q0J A;  3SFP A;  1YCF A;  4C1H A;  3IDZ A;  2Q9U A;  2OHJ A;  3DH8 A;  3KNS A;  4H0D A;  2XR1 A;  5EV8 A;  5KIK A;  5ACP A;  3AF6 A;  1SML A;  3X2Y A;  2FHX B;  4UBQ A;  4XUK A;  3KNR A;  2P1E A;  3PG4 A;  2GKL A;  4YSL A;  3ESH A;  5B3R A;  1WW1 A;  1WUP A;  3PY5 A;  4UWP B;  4D1V A;  1BMC A;  3DHB A;  1ZKP A;  2YCB A;  4TZ9 A;  1P9E A;  2NYP A;  3BK2 A;  4RL0 A;  5FQB A;  2GFJ A;  4B87 A;  4AD9 A;  3FAI A;  3FCZ A;  5AXO A;  3DHC A;  4C1D A;  3I14 A;  3ZWF A;  2WHG A;  4EY2 A;  1K07 A;  2GFK A;  2VW8 A;  4HL2 A;  1YCH A;  2FHX A;  5EH9 A;  3X2Z A;  4EXS A;  2YZ3 A;  3MD7 A;  2H6A A;  3VQZ A;  3ADR A;  4V0H A;  2M5D A;  1M2X A;  4UWS B;  2Q0I A;  1WUO A;  2QIN A;  4LE6 A;  2UYX A;  1VME A;  4FR7 A;  5DPX A;  2QDT A;  2WYL A;  2R2D A;  3T3O A;  5LCF A;  3IEL A;  3PY6 A;  1HLK A;  3SW3 A;  1KO3 A;  4RM5 A;  5LSC A;  4BZ3 A;  2BFL A;  5FQA A;  3I0V A;  4UAM A;  2Y87 A;  2BG2 A;  4RAW A;  4XWT A;  4NQ2 A;  4YSB A;  5EVD A;  5EVK A;  2Y8A A;  2YNV B;  3I13 A;  5LE1 A;  2NXA A;  4RL2 A;  5K4M A;  3ZNB A;  2WYM A;  4J5F A;  3SRX A;  2BG8 B;  5EW0 A;  4EYF A;  3R2U A;  1BC2 A;  1VGN A;  1XM8 A;  3IEK A;  4ZO2 A;  4D1T A;  3IE0 A;  2WRS A;  4YSK A;  4O98 A;  4KEP A;  4WD6 A;  3SBL A;  5HIS A;  4UWR B;  2P18 A;  1YCG A;  5ACR A;  4FEK A;  5B15 A;  5IQK A;  2XF4 A;  3DHA A;  3SD9 A;  2OHI A;  4C09 A;  4AWY B;  2A7M A;  5EHT A;  2Y8B A;  5LM6 A;  3L6N A;  2DOO A;  5ACX A;  2YNW A;  2YNV A;  4KEQ A;  2NZF A;  1E5D A;  1KO2 A;  5ACS A;  5EV6 A;  4RAM A;  4HKY A;  4TYF A;  2BG8 A;  4NQ4 A;  4ZEJ A;  3I11 A;  5AEB A;  3BK1 A;  5ACQ A;  2P4Z A;  5KIL A;  3RPC A;  1MQO A;  5AHR A;  5FQC A;  2BFZ B;  2NZE A;  3F9O A;  5LMC A;  4FSB A;  1JT1 A;  5HH5 A;  2FK6 A;  2WYM C;  2HB9 A;  3T3N A;  2YNT B;  3BV6 A;  4P62 A;  1JJT A;  4TZB A;  2BFK A;  2FU6 A;  4GCW A;  3TP9 A;  1VJN A;  3ZQ4 A;  5EVB A;  4DIL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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