5K4PA

Catalytic domain of mcr-1 phosphoethanolamine transferase
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
Knots found
sequence length
324
structure length
323
Chain Sequence
DTIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the catalytic domain of the colistin resistance enzyme MCR-1.
pubmed doi rcsb
molecule tags Transferase
molecule keywords Probable phosphatidylethanolamine transferase Mcr-1
total genus 125
structure length 323
sequence length 324
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5k4pA00
1ELZA 2D1GA 2W5RA 4LQYA 1KH7A 1Y7AA 3MK1A 2QZUA 2W5SA 1ELYA 4CYSA 2ANHA 2W5QA 2X98A 4MIVA 3Q3QA 1ED9A 4N7TA 1KHNA 4ZG7A 4QAXA 1KHLA 1ALHA 2GA3A 1URAA 3BDFA 3IDDA 3NKQA 4KJDA 4MY4A 4TN0A 4ZG6A 3IGZB 5LIAA 1HQAA 4LR7A 5L0KA 1AJDA 1ZEBA 2XRGA 5EGHA 5DLTA 5AJ9A 4CYRA 5DLWA 1N2LA 3WBHA 3MK2A 4LRFA 4B56A 5L0BA 2W8SA 4KAYA 3UO0A 1EW8A 3DYCA 4LRDA 3M8YA 2RH6A 4CXUA 3NVLA 2G9YA 3M8WA 2IUCB 1E1ZP 1SHNA 3BDGA 4KJGA 3WAWA 1ALIA 2W5XA 3CMRA 1ZEDA 3T01A 4UPKA 1O99A 1KHJA 5C66A 4UPLA 1KH4A 3BDGB 1E3CP 4GTYA 4ZG9A 5LQQA 4UOOA 4GTZA 1AJBA 1ZEFA 1ELXA 1AJAA 1E33P 1EW2A 1K7HA 2IUCA 3B5QA 1HJKA 1ALKA 1KH5A 3WAVA 5IJSA 1KHKA 3UNYA 4NWJA 3NKRA 1FSUA 2IFYA 3WAYA 3M8ZA 1N2KA 1AJCA 3LXQA 1AUKA 5TJ3A 3IGYB 1EW9A 4KAVA 5LRNA 1B8JA 5GOVA 4LR8A 3OT9A 3MK0A 1SHQA 3TX0A 5GRRA 3T02A 2W5WA 3DPCA 1ANIA 1E2SP 4GTXA 4KM4A 3NKPA 3E2DA 1EJJA 2GLQA 3NKOA 3NKNA 3A52A 1ALJA 2GSOA 1Y6VA 4FDJA 3SZYA 1O98A 5L0EA 1ANJA 2W5TA 4FDIA 4LRBA 2XR9A 3WAXA 4NWXA 1KH9A 2GSNA 4UORA 1HDHA 3SZZA 4CXKA 4GTWA 5LRMA 4LRAA 3NKMA 4UPHA 3T00A 2GSUA 2W5VA 2VQRA 4ZGAA 2ZKTA 3M7VA 1EQJA 3UN3A 1P49A 4CXSA 3BDHA 2W8DA 4LREA 3UN2A 3ED4A 4LR2A 5DLVA 3TG0A 3KD8A 3TWZA 4MHXA 5HRTA 4YR1A 4UPIA 5EGEA 5INHA 1EI6A 4LRCA 5IJQA 1ED8A 3UN5A 5KXAA 1URBA 4LR9A 4UOPA 5K4PA
chains in the Genus database with same CATH superfamily
1ELZA 2D1GA 2W5RA 4LQYA 1KH7A 1Y7AA 3MK1A 2QZUA 2W5SA 1ELYA 4CYSA 2ANHA 2W5QA 2X98A 4MIVA 3Q3QA 1ED9A 4N7TA 1KHNA 4ZG7A 4QAXA 1KHLA 1ALHA 2GA3A 1URAA 3BDFA 3IDDA 3NKQA 4KJDA 4MY4A 4TN0A 4ZG6A 3IGZB 5LIAA 1HQAA 4LR7A 5L0KA 1AJDA 1ZEBA 2XRGA 5EGHA 5DLTA 5AJ9A 4CYRA 5DLWA 1N2LA 3WBHA 3MK2A 4LRFA 4B56A 5L0BA 2W8SA 4KAYA 3UO0A 1EW8A 3DYCA 4LRDA 3M8YA 2RH6A 4CXUA 3NVLA 2G9YA 3M8WA 2IUCB 1E1ZP 1SHNA 3BDGA 4KJGA 3WAWA 1ALIA 2W5XA 3CMRA 1ZEDA 3T01A 4UPKA 1O99A 1KHJA 5C66A 4UPLA 1KH4A 3BDGB 1E3CP 4GTYA 4ZG9A 5LQQA 4UOOA 4GTZA 1AJBA 1ZEFA 1ELXA 1AJAA 1E33P 1EW2A 1K7HA 2IUCA 3B5QA 1HJKA 1ALKA 1KH5A 3WAVA 5IJSA 1KHKA 3UNYA 4NWJA 3NKRA 1FSUA 2IFYA 3WAYA 3M8ZA 1N2KA 1AJCA 3LXQA 1AUKA 5TJ3A 3IGYB 1EW9A 4KAVA 5LRNA 1B8JA 5GOVA 4LR8A 3OT9A 3MK0A 1SHQA 3TX0A 5GRRA 3T02A 2W5WA 3DPCA 1ANIA 1E2SP 4GTXA 4KM4A 3NKPA 3E2DA 1EJJA 2GLQA 3NKOA 3NKNA 3A52A 1ALJA 2GSOA 1Y6VA 4FDJA 3SZYA 1O98A 5L0EA 1ANJA 2W5TA 4FDIA 4LRBA 2XR9A 3WAXA 4NWXA 1KH9A 2GSNA 4UORA 1HDHA 3SZZA 4CXKA 4GTWA 5LRMA 4LRAA 3NKMA 4UPHA 3T00A 2GSUA 2W5VA 2VQRA 4ZGAA 2ZKTA 3M7VA 1EQJA 3UN3A 1P49A 4CXSA 3BDHA 2W8DA 4LREA 3UN2A 3ED4A 4LR2A 5DLVA 3TG0A 3KD8A 3TWZA 4MHXA 5HRTA 4YR1A 4UPIA 5EGEA 5INHA 1EI6A 4LRCA 5IJQA 1ED8A 3UN5A 5KXAA 1URBA 4LR9A 4UOPA 5K4PA
chains in the Genus database with same CATH topology
1ELZA 2D1GA 2W5RA 4LQYA 1KH7A 1Y7AA 3MK1A 2QZUA 2W5SA 1ELYA 4CYSA 2ANHA 2W5QA 2X98A 4MIVA 3Q3QA 1ED9A 4N7TA 1KHNA 4ZG7A 4QAXA 1KHLA 1ALHA 2GA3A 1URAA 3BDFA 3IDDA 3NKQA 4KJDA 4MY4A 4TN0A 4ZG6A 3IGZB 5LIAA 1HQAA 4LR7A 5L0KA 1AJDA 1ZEBA 2XRGA 5EGHA 5DLTA 5AJ9A 4CYRA 5DLWA 1N2LA 3WBHA 3MK2A 4LRFA 4B56A 5L0BA 2W8SA 4KAYA 3UO0A 1EW8A 3DYCA 4LRDA 3M8YA 2RH6A 4CXUA 3NVLA 2G9YA 3M8WA 2IUCB 1E1ZP 1SHNA 3BDGA 4KJGA 3WAWA 1ALIA 2W5XA 3CMRA 1ZEDA 3T01A 4UPKA 1O99A 1KHJA 5C66A 4UPLA 1KH4A 3BDGB 1E3CP 4GTYA 4ZG9A 5LQQA 4UOOA 4GTZA 1AJBA 1ZEFA 1ELXA 1AJAA 1E33P 1EW2A 1K7HA 2IUCA 3B5QA 1HJKA 1ALKA 1KH5A 3WAVA 5IJSA 1KHKA 3UNYA 4NWJA 3NKRA 1FSUA 2IFYA 3WAYA 3M8ZA 1N2KA 1AJCA 3LXQA 1AUKA 5TJ3A 3IGYB 1EW9A 4KAVA 5LRNA 1B8JA 5GOVA 4LR8A 3OT9A 3MK0A 1SHQA 3TX0A 5GRRA 3T02A 2W5WA 3DPCA 1ANIA 1E2SP 4GTXA 4KM4A 3NKPA 3E2DA 1EJJA 2GLQA 3NKOA 3NKNA 3A52A 1ALJA 2GSOA 1Y6VA 4FDJA 3SZYA 1O98A 5L0EA 1ANJA 2W5TA 4FDIA 4LRBA 2XR9A 3WAXA 4NWXA 1KH9A 2GSNA 4UORA 1HDHA 3SZZA 4CXKA 4GTWA 5LRMA 4LRAA 3NKMA 4UPHA 3T00A 2GSUA 2W5VA 2VQRA 4ZGAA 2ZKTA 3M7VA 1EQJA 3UN3A 1P49A 4CXSA 3BDHA 2W8DA 4LREA 3UN2A 3ED4A 4LR2A 5DLVA 3TG0A 3KD8A 3TWZA 4MHXA 5HRTA 4YR1A 4UPIA 5EGEA 5INHA 1EI6A 4LRCA 5IJQA 1ED8A 3UN5A 5KXAA 1URBA 4LR9A 4UOPA 5K4PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ELZ A;  2D1G A;  2W5R A;  4LQY A;  1KH7 A;  1Y7A A;  3MK1 A;  2QZU A;  2W5S A;  1ELY A;  4CYS A;  2ANH A;  2W5Q A;  2X98 A;  4MIV A;  3Q3Q A;  1ED9 A;  4N7T A;  1KHN A;  4ZG7 A;  4QAX A;  1KHL A;  1ALH A;  2GA3 A;  1URA A;  3BDF A;  3IDD A;  3NKQ A;  4KJD A;  4MY4 A;  4TN0 A;  4ZG6 A;  3IGZ B;  5LIA A;  1HQA A;  4LR7 A;  5L0K A;  1AJD A;  1ZEB A;  2XRG A;  5EGH A;  5DLT A;  5AJ9 A;  4CYR A;  5DLW A;  1N2L A;  3WBH A;  3MK2 A;  4LRF A;  4B56 A;  5L0B A;  2W8S A;  4KAY A;  3UO0 A;  1EW8 A;  3DYC A;  4LRD A;  3M8Y A;  2RH6 A;  4CXU A;  3NVL A;  2G9Y A;  3M8W A;  2IUC B;  1E1Z P;  1SHN A;  3BDG A;  4KJG A;  3WAW A;  1ALI A;  2W5X A;  3CMR A;  1ZED A;  3T01 A;  4UPK A;  1O99 A;  1KHJ A;  5C66 A;  4UPL A;  1KH4 A;  3BDG B;  1E3C P;  4GTY A;  4ZG9 A;  5LQQ A;  4UOO A;  4GTZ A;  1AJB A;  1ZEF A;  1ELX A;  1AJA A;  1E33 P;  1EW2 A;  1K7H A;  2IUC A;  3B5Q A;  1HJK A;  1ALK A;  1KH5 A;  3WAV A;  5IJS A;  1KHK A;  3UNY A;  4NWJ A;  3NKR A;  1FSU A;  2IFY A;  3WAY A;  3M8Z A;  1N2K A;  1AJC A;  3LXQ A;  1AUK A;  5TJ3 A;  3IGY B;  1EW9 A;  4KAV A;  5LRN A;  1B8J A;  5GOV A;  4LR8 A;  3OT9 A;  3MK0 A;  1SHQ A;  3TX0 A;  5GRR A;  3T02 A;  2W5W A;  3DPC A;  1ANI A;  1E2S P;  4GTX A;  4KM4 A;  3NKP A;  3E2D A;  1EJJ A;  2GLQ A;  3NKO A;  3NKN A;  3A52 A;  1ALJ A;  2GSO A;  1Y6V A;  4FDJ A;  3SZY A;  1O98 A;  5L0E A;  1ANJ A;  2W5T A;  4FDI A;  4LRB A;  2XR9 A;  3WAX A;  4NWX A;  1KH9 A;  2GSN A;  4UOR A;  1HDH A;  3SZZ A;  4CXK A;  4GTW A;  5LRM A;  4LRA A;  3NKM A;  4UPH A;  3T00 A;  2GSU A;  2W5V A;  2VQR A;  4ZGA A;  2ZKT A;  3M7V A;  1EQJ A;  3UN3 A;  1P49 A;  4CXS A;  3BDH A;  2W8D A;  4LRE A;  3UN2 A;  3ED4 A;  4LR2 A;  5DLV A;  3TG0 A;  3KD8 A;  3TWZ A;  4MHX A;  5HRT A;  4YR1 A;  4UPI A;  5EGE A;  5INH A;  1EI6 A;  4LRC A;  5IJQ A;  1ED8 A;  3UN5 A;  5KXA A;  1URB A;  4LR9 A;  4UOP A;  5K4P A; 
#chains in the Genus database with same CATH topology
 1ELZ A;  2D1G A;  2W5R A;  4LQY A;  1KH7 A;  1Y7A A;  3MK1 A;  2QZU A;  2W5S A;  1ELY A;  4CYS A;  2ANH A;  2W5Q A;  2X98 A;  4MIV A;  3Q3Q A;  1ED9 A;  4N7T A;  1KHN A;  4ZG7 A;  4QAX A;  1KHL A;  1ALH A;  2GA3 A;  1URA A;  3BDF A;  3IDD A;  3NKQ A;  4KJD A;  4MY4 A;  4TN0 A;  4ZG6 A;  3IGZ B;  5LIA A;  1HQA A;  4LR7 A;  5L0K A;  1AJD A;  1ZEB A;  2XRG A;  5EGH A;  5DLT A;  5AJ9 A;  4CYR A;  5DLW A;  1N2L A;  3WBH A;  3MK2 A;  4LRF A;  4B56 A;  5L0B A;  2W8S A;  4KAY A;  3UO0 A;  1EW8 A;  3DYC A;  4LRD A;  3M8Y A;  2RH6 A;  4CXU A;  3NVL A;  2G9Y A;  3M8W A;  2IUC B;  1E1Z P;  1SHN A;  3BDG A;  4KJG A;  3WAW A;  1ALI A;  2W5X A;  3CMR A;  1ZED A;  3T01 A;  4UPK A;  1O99 A;  1KHJ A;  5C66 A;  4UPL A;  1KH4 A;  3BDG B;  1E3C P;  4GTY A;  4ZG9 A;  5LQQ A;  4UOO A;  4GTZ A;  1AJB A;  1ZEF A;  1ELX A;  1AJA A;  1E33 P;  1EW2 A;  1K7H A;  2IUC A;  3B5Q A;  1HJK A;  1ALK A;  1KH5 A;  3WAV A;  5IJS A;  1KHK A;  3UNY A;  4NWJ A;  3NKR A;  1FSU A;  2IFY A;  3WAY A;  3M8Z A;  1N2K A;  1AJC A;  3LXQ A;  1AUK A;  5TJ3 A;  3IGY B;  1EW9 A;  4KAV A;  5LRN A;  1B8J A;  5GOV A;  4LR8 A;  3OT9 A;  3MK0 A;  1SHQ A;  3TX0 A;  5GRR A;  3T02 A;  2W5W A;  3DPC A;  1ANI A;  1E2S P;  4GTX A;  4KM4 A;  3NKP A;  3E2D A;  1EJJ A;  2GLQ A;  3NKO A;  3NKN A;  3A52 A;  1ALJ A;  2GSO A;  1Y6V A;  4FDJ A;  3SZY A;  1O98 A;  5L0E A;  1ANJ A;  2W5T A;  4FDI A;  4LRB A;  2XR9 A;  3WAX A;  4NWX A;  1KH9 A;  2GSN A;  4UOR A;  1HDH A;  3SZZ A;  4CXK A;  4GTW A;  5LRM A;  4LRA A;  3NKM A;  4UPH A;  3T00 A;  2GSU A;  2W5V A;  2VQR A;  4ZGA A;  2ZKT A;  3M7V A;  1EQJ A;  3UN3 A;  1P49 A;  4CXS A;  3BDH A;  2W8D A;  4LRE A;  3UN2 A;  3ED4 A;  4LR2 A;  5DLV A;  3TG0 A;  3KD8 A;  3TWZ A;  4MHX A;  5HRT A;  4YR1 A;  4UPI A;  5EGE A;  5INH A;  1EI6 A;  4LRC A;  5IJQ A;  1ED8 A;  3UN5 A;  5KXA A;  1URB A;  4LR9 A;  4UOP A;  5K4P A; 
#chains in the Genus database with same CATH homology
 1ELZ A;  2D1G A;  2W5R A;  4LQY A;  1KH7 A;  1Y7A A;  3MK1 A;  2QZU A;  2W5S A;  1ELY A;  4CYS A;  2ANH A;  2W5Q A;  2X98 A;  4MIV A;  3Q3Q A;  1ED9 A;  4N7T A;  1KHN A;  4ZG7 A;  4QAX A;  1KHL A;  1ALH A;  2GA3 A;  1URA A;  3BDF A;  3IDD A;  3NKQ A;  4KJD A;  4MY4 A;  4TN0 A;  4ZG6 A;  3IGZ B;  5LIA A;  1HQA A;  4LR7 A;  5L0K A;  1AJD A;  1ZEB A;  2XRG A;  5EGH A;  5DLT A;  5AJ9 A;  4CYR A;  5DLW A;  1N2L A;  3WBH A;  3MK2 A;  4LRF A;  4B56 A;  5L0B A;  2W8S A;  4KAY A;  3UO0 A;  1EW8 A;  3DYC A;  4LRD A;  3M8Y A;  2RH6 A;  4CXU A;  3NVL A;  2G9Y A;  3M8W A;  2IUC B;  1E1Z P;  1SHN A;  3BDG A;  4KJG A;  3WAW A;  1ALI A;  2W5X A;  3CMR A;  1ZED A;  3T01 A;  4UPK A;  1O99 A;  1KHJ A;  5C66 A;  4UPL A;  1KH4 A;  3BDG B;  1E3C P;  4GTY A;  4ZG9 A;  5LQQ A;  4UOO A;  4GTZ A;  1AJB A;  1ZEF A;  1ELX A;  1AJA A;  1E33 P;  1EW2 A;  1K7H A;  2IUC A;  3B5Q A;  1HJK A;  1ALK A;  1KH5 A;  3WAV A;  5IJS A;  1KHK A;  3UNY A;  4NWJ A;  3NKR A;  1FSU A;  2IFY A;  3WAY A;  3M8Z A;  1N2K A;  1AJC A;  3LXQ A;  1AUK A;  5TJ3 A;  3IGY B;  1EW9 A;  4KAV A;  5LRN A;  1B8J A;  5GOV A;  4LR8 A;  3OT9 A;  3MK0 A;  1SHQ A;  3TX0 A;  5GRR A;  3T02 A;  2W5W A;  3DPC A;  1ANI A;  1E2S P;  4GTX A;  4KM4 A;  3NKP A;  3E2D A;  1EJJ A;  2GLQ A;  3NKO A;  3NKN A;  3A52 A;  1ALJ A;  2GSO A;  1Y6V A;  4FDJ A;  3SZY A;  1O98 A;  5L0E A;  1ANJ A;  2W5T A;  4FDI A;  4LRB A;  2XR9 A;  3WAX A;  4NWX A;  1KH9 A;  2GSN A;  4UOR A;  1HDH A;  3SZZ A;  4CXK A;  4GTW A;  5LRM A;  4LRA A;  3NKM A;  4UPH A;  3T00 A;  2GSU A;  2W5V A;  2VQR A;  4ZGA A;  2ZKT A;  3M7V A;  1EQJ A;  3UN3 A;  1P49 A;  4CXS A;  3BDH A;  2W8D A;  4LRE A;  3UN2 A;  3ED4 A;  4LR2 A;  5DLV A;  3TG0 A;  3KD8 A;  3TWZ A;  4MHX A;  5HRT A;  4YR1 A;  4UPI A;  5EGE A;  5INH A;  1EI6 A;  4LRC A;  5IJQ A;  1ED8 A;  3UN5 A;  5KXA A;  1URB A;  4LR9 A;  4UOP A;  5K4P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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