5K59A

Crystal structure of lukgh from staphylococcus aureus in complex with a neutralising antibody
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
295
structure length
292
Chain Sequence
EKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Uncharacterized leukocidin-like protein 2
publication title Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
pubmed doi rcsb
source organism Staphylococcus aureus (strain usa300)
total genus 75
structure length 292
sequence length 295
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 5k59A00
1T5RA 2YGTA 4IYAA 4I0NA 4H56A 2QK7B 5K59A 3B07B 4P1XB 5K59C 1PVLA 4P1YA 7AHLA 4TW1A 3M2LA 3M4DA 4YHDA 4IZLA 4Q7GA 3ROHA 2QK7A 3B07A 2LKFA 4P24A 3M4EA 4IYTA 4P1XA 3O44A 4IDJA 4P1YB 4U6VA 4TW1B 4IYCA 3ANZA 4J0OA 3M3RA 1LKFA 3LKFA
chains in the Genus database with same CATH superfamily
1T5RA 1XEZA 2YGTA 4IYAA 4I0NA 4H56A 2QK7B 5K59A 3B07B 4P1XB 5K59C 1PVLA 4P1YA 7AHLA 4TW1A 3M2LA 3M4DA 4YHDA 4IZLA 4Q7GA 3ROHA 2QK7A 3B07A 2LKFA 4P24A 3M4EA 4IYTA 4P1XA 3O44A 4IDJA 4P1YB 4U6VA 4TW1B 4IYCA 3ANZA 4J0OA 3M3RA 1LKFA 3LKFA
chains in the Genus database with same CATH topology
1T5RA 2YGTA 4IYAA 4I0NA 4H56A 2QK7B 5K59A 3B07B 4P1XB 5K59C 1PVLA 4P1YA 7AHLA 4TW1A 3M2LA 3M4DA 4YHDA 4IZLA 4Q7GA 3ROHA 2QK7A 3B07A 2LKFA 4P24A 3M4EA 4IYTA 4P1XA 3O44A 4IDJA 4P1YB 4U6VA 4TW1B 4IYCA 3ANZA 4J0OA 3M3RA 1LKFA 3LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T5R A;  2YGT A;  4IYA A;  4I0N A;  4H56 A;  2QK7 B;  5K59 A;  3B07 B;  4P1X B;  5K59 C;  1PVL A;  4P1Y A;  7AHL A;  4TW1 A;  3M2L A;  3M4D A;  4YHD A;  4IZL A;  4Q7G A;  3ROH A;  2QK7 A;  3B07 A;  2LKF A;  4P24 A;  3M4E A;  4IYT A;  4P1X A;  3O44 A;  4IDJ A;  4P1Y B;  4U6V A;  4TW1 B;  4IYC A;  3ANZ A;  4J0O A;  3M3R A;  1LKF A;  3LKF A; 
#chains in the Genus database with same CATH topology
 1T5R A;  1XEZ A;  2YGT A;  4IYA A;  4I0N A;  4H56 A;  2QK7 B;  5K59 A;  3B07 B;  4P1X B;  5K59 C;  1PVL A;  4P1Y A;  7AHL A;  4TW1 A;  3M2L A;  3M4D A;  4YHD A;  4IZL A;  4Q7G A;  3ROH A;  2QK7 A;  3B07 A;  2LKF A;  4P24 A;  3M4E A;  4IYT A;  4P1X A;  3O44 A;  4IDJ A;  4P1Y B;  4U6V A;  4TW1 B;  4IYC A;  3ANZ A;  4J0O A;  3M3R A;  1LKF A;  3LKF A; 
#chains in the Genus database with same CATH homology
 1T5R A;  2YGT A;  4IYA A;  4I0N A;  4H56 A;  2QK7 B;  5K59 A;  3B07 B;  4P1X B;  5K59 C;  1PVL A;  4P1Y A;  7AHL A;  4TW1 A;  3M2L A;  3M4D A;  4YHD A;  4IZL A;  4Q7G A;  3ROH A;  2QK7 A;  3B07 A;  2LKF A;  4P24 A;  3M4E A;  4IYT A;  4P1X A;  3O44 A;  4IDJ A;  4P1Y B;  4U6V A;  4TW1 B;  4IYC A;  3ANZ A;  4J0O A;  3M3R A;  1LKF A;  3LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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