5KA0A

Protein tyrosine phosphatase 1b delta helix 7, open state
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
281
structure length
281
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 102
structure length 281
sequence length 281
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka0A00
3QCLA 4JMJA 1PYNA 1KAVA 3QCDA 4OHEA 2SHPA 3U96A 2HVLA 1LYVA 5K9VA 2I5XA 2CM8A 5KA1A 3F9BA 4D3QA 1ZCKA 2I4GA 4R0TA 5K25A 1RXDA 1U26A 3H2XA 3O5XA 3ZM0A 4H34A 2P4DA 4PYHA 1XBOA 2Q47A 3EAXA 2CMCA 1QZ0A 5KA0A 3BM8A 1NWEA 2BGDA 1JF7A 1I9SA 2QBRA 2OZ5A 2QDPA 3BLUA 2VEYA 2I42A 1G4WR 4KYRA 1ECVA 1OHCA 5HDEA 2J17A 3V0JA 4RI5A 3BRHA 2CMAA 4JBCA 2I75A 3BLTA 5BX1A 2CMBA 2VEWA 1YWFA 5KACA 4R0SA 1I57A 1OEMX 2IMGA 5KA4A 1WCHA 2Y96A 3S3KA 2B4SA 5IBSA 2J16B 3QCHA 2VEVA 3AWFA 2CFVA 2C46A 1YTSA 2I4HA 5EHPA 1WAXA 5I6VA 1X24A 1JLNA 1P15A 2G59A 2NLKA 3O4TA 1OETA 1LARA 4D3PA 3B7OA 3CWEA 2GP0A 4PVGA 3O4UA 3MMJA 4GE6A 2HCMA 2H03A 4WU3A 2AZRA 3V0GA 3QKQA 5EHRA 1SUGA 1PTTA 1NO6A 4RH9A 1C86A 2PI7A 1FPRA 3SMEA 4GRYA 2I6PA 1G1FA 2BZLA 2F6FA 3QCMA 4ZI4A 1YGRA 1YPTA 1EEOA 1G1GA 5KAAA 2QCJA 2PSZA 3S4EA 1BZJA 2F6TA 3NMEA 2F71A 2H04A 1YZ4A 4DGPA 3I7ZA 4MBBA 4GE5A 1YTWA 4WOHA 5GTJA 1T48A 3QCCA 2ZN7A 4WU2A 2I6OA 2QDMA 4ERCA 4H1OA 4ZRTA 1LQFA 2HC2A 2QBSA 5KABA 5KA9A 2FJNA 4QBEA 1Q6PA 1M3GA 3I80A 1G7FA 1XXVA 3S3EA 2I3UA 2HNQA 2ZMMA 4OHLA 2NV5A 2F6ZA 1PTYA 5K9WA 1PTVA 5M43A 1YTNA 1ZZWA 3D1OA 4RHGA 2CNHA 3S3HA 3N0AA 2I6JA 1NNYA 2F70A 2F6VA 2H4VA 4R30A 1YFOA 4GFUA 3V0DA 1U24A 4YAAA 3QKPA 3D9CA 2F6YA 3D1HA 3RGQA 2A3KA 1VHRA 2ESBA 2B49A 1Q6SA 4NWFA 5KA2A 4QAPA 1V3AA 2Q05A 2PT0A 4HJQA 3F99A 2HB1A 3EU0A 3ZMQA 3V0IA 3AWEA 5BZZA 3O3LA 4AZ1A 3D42A 3I36A 1OEVA 2E0TA 2HNPA 2NTAA 4J51A 2HY3A 4D3RA 2HXPA 3V0HA 3ZM1A 2OC3A 1PA9A 1ZCLA 1BZCA 3F9AA 5K22A 2FH7A 2G6ZA 3OMHA 1G4US 3QCIA 4S0GA 4Z6BA 1NWLA 2I1YA 5IBMA 1L8KA 5KA3A 3EZZA 1C87A 2BIJA 3PS5A 2NT2A 2VEUA 1GFYA 1XXPA 1PA1A 4TVVA 1Q6JA 1A5YA 3OLRA 3A5JA 2P6XA 1RPMA 3QCNA 4ICZA 2QEPA 4B04A 3GXGA 1T49A 1T4JA 4GRZA 3ZM3A 4NWGA 3D44A 1Q6NA 1L8GA 1Q6MA 3ZMPA 2QBPA 4I8NA 2GWOA 2H02A 1C83A 4BJOA 1AAXA 2YDUA 4NYHA 2F6WA 3S3FA 1J4XA 1G1HA 5KA7A 2PQ5A 4OHDA 4WTYA 5MMZB 2GJTA 4QAHA 3F81A 1YN9A 3GXHA 2RF6A 1ONYA 3MOWA 1KAKA 3ZV2A 2CNEA 2I6MA 3CM3A 2I6IA 4HRFA 1G7GA 2B3OA 4RDDA 2I3RA 4IKCA 4JNBA 2PA5A 1YGUA 2H4KA 4GE2A 4JMKA 5J8RA 4QUMA 3QCEA 1XM2A 2B07A 4RI4A 2H4GA 2WGPA 3LJ8A 3EMUA 4QBWA 5BZXA 4RKKA 2QBQA 3RGOA 2BV5A 2MBCA 1BZHA 1OHDA 2R0BA 3QCBA 2NZ6A 2C7SA 3RO1A 2Y2FA 1Q6TA 1R6HA 2OOQA 4GWFA 1OESA 3QCKA 1OEUA 1ONZA 4DGXA 2QCTA 1FQ1A 4HJPA 5KA8A 3A5KA 3SR9A 2CJZA 2DXPA 1C84A 3QCFA 5BUGA 2VEXA 1C88A 4BPCA 2F46A 4OHIA 2FJMA 2CM2A 5KADA 1C85A 2CM3A 1PH0A 3MOZA 4YR8B 4OHHA 2PBNA 3QCJA 1OHEA 3QCGA 5K24A 1NZ7A 5LXQB 1GWZA 1ZC0A 1FPZA 4KYQA 4RH5A 4NNDA 4Y14A 2CNGA 2HC1A 2AHSA 4QUNA 1MKPA 3AWGA 2B4OA 1EENA 1QXKA 1NL9A 3V0EA 3D1QA 1WRMA 3RZ2A 1PTUA 2B4UA 2OUDA 1Q1MA 2J16A 1U25A 2B4PA 2CNFA 3M4UA 1XRIA 1OEOX 4ZN5A 1PXHA 4GFVA 3F41A 3V0FA 4KI9A 2M3VA 3EB1A 4NX8A 2NT7A 2A8BA 5K23A 3ZM2A 2BGEA 5AWXA 2QDCA 4GS0A 3S4OA 4Y2EA 3O4SA 2JJDA 1I9TA 2CM7A 1D5RA 2I4EA 2CNIA
chains in the Genus database with same CATH superfamily
3QCLA 4JMJA 1PYNA 1KAVA 3QCDA 4OHEA 2SHPA 3U96A 2HVLA 1LYVA 5K9VA 2I5XA 2CM8A 5KA1A 3F9BA 4D3QA 1ZCKA 2I4GA 4R0TA 5K25A 1RXDA 1U26A 3H2XA 3O5XA 3ZM0A 1FGSA 4H34A 2P4DA 4PYHA 1XBOA 2JFGA 2Q47A 3EAXA 2CMCA 1QZ0A 2XJAA 5KA0A 3BM8A 1NWEA 2BGDA 1JF7A 1I9SA 2QBRA 2OZ5A 2QDPA 3BLUA 2VEYA 2I42A 1G4WR 4KYRA 1ECVA 1OHCA 5HDEA 2J17A 3V0JA 4RI5A 3BRHA 2CMAA 4JBCA 2I75A 3BLTA 4CVLA 2CMBA 5BX1A 2VEWA 3LK7A 1YWFA 5KACA 4R0SA 2F00A 1I57A 1OEMX 2IMGA 5KA4A 1WCHA 2Y96A 3S3KA 1GQQA 2B4SA 5IBSA 1EEHA 2J16B 3QCHA 2VEVA 3AWFA 2CFVA 2C46A 1YTSA 2I4HA 2VORA 5EHPA 1WAXA 5I6VA 1X24A 1JLNA 1P15A 2G59A 2NLKA 2VOSA 3O4TA 1OETA 1LARA 4HV4A 4D3PA 3B7OA 3CWEA 2GP0A 3ZM6A 4PVGA 3O4UA 2X5OA 3MMJA 2HCMA 4GE6A 2H03A 4WU3A 2AZRA 3V0GA 3QKQA 5EHRA 1SUGA 1PTTA 4CVKA 1NO6A 1W7KA 4RH9A 1C86A 2PI7A 1FPRA 5A5EA 3SMEA 4GRYA 2I6PA 1G1FA 2BZLA 2F6FA 3QCMA 4ZI4A 1YGRA 1YPTA 1EEOA 2VTDA 1G1GA 5KAAA 2QCJA 2PSZA 3S4EA 1BZJA 2JFHA 2F6TA 3NMEA 2F71A 2H04A 1YZ4A 4DGPA 3I7ZA 4MBBA 4GE5A 1YTWA 4WOHA 5GTJA 1T48A 3MVNA 3QCCA 1J6UA 2ZN7A 4WU2A 2I6OA 5A5FA 2QDMA 4ERCA 4H1OA 4ZRTA 1LQFA 2HC2A 2QBSA 5KABA 5KA9A 2FJNA 4QBEA 1Q6PA 1M3GA 3I80A 1G7FA 1XXVA 1JBVA 3S3EA 2I3UA 2HNQA 2ZMMA 4OHLA 2NV5A 2F6ZA 1PTYA 5K9WA 1PTVA 5M43A 1YTNA 1ZZWA 3D1OA 4RHGA 2CNHA 4BUBA 2VTEA 3S3HA 3ZL8A 3N0AA 2I6JA 2GC5A 1NNYA 2F70A 2F6VA 2H4VA 4R30A 1JBWA 1YFOA 4GFUA 3V0DA 2WJPA 1U24A 4YAAA 3QKPA 3D9CA 2F6YA 3D1HA 3RGQA 2A3KA 1VHRA 2ESBA 2B49A 1Q6SA 4NWFA 5KA2A 4QAPA 1V3AA 4QF5A 2Q05A 2PT0A 4HJQA 3F99A 2HB1A 2WTZA 3EU0A 3ZMQA 3V0IA 3AWEA 5BZZA 1UAGA 3O3LA 4AZ1A 3D42A 3I36A 1OEVA 2E0TA 2HNPA 2NTAA 4J51A 1P3DA 2HY3A 4D3RA 2HXPA 3V0HA 3ZM1A 2OC3A 1PA9A 1ZCLA 1BZCA 3F9AA 5K22A 2FH7A 2G6ZA 3OMHA 1G4US 3QCIA 4CVMA 4S0GA 4Z6BA 1NWLA 2Y67A 2I1YA 5IBMA 1L8KA 5KA3A 3EZZA 3UAGA 1C87A 2BIJA 3PS5A 2NT2A 2VEUA 1GFYA 1XXPA 1PA1A 4TVVA 1Q6JA 1A5YA 3OLRA 3A5JA 2P6XA 1RPMA 2UUOA 3QCNA 4ICZA 2QEPA 4B04A 3GXGA 1T49A 4ZIYA 1T4JA 4GRZA 3ZM3A 4NWGA 3D44A 1Q6NA 1E8CA 1L8GA 1Q6MA 3ZMPA 2Y66A 2QBPA 4I8NA 2GWOA 2H02A 1C83A 4BJOA 1AAXA 4UAGA 2YDUA 2GCAA 4NYHA 2F6WA 3S3FA 1J4XA 1G1HA 3QCZA 5KA7A 2PQ5A 4OHDA 4WTYA 5MMZB 2GJTA 4QAHA 1YN9A 3F81A 3GXHA 2RF6A 1ONYA 3MOWA 1KAKA 3ZV2A 2CNEA 2I6MA 3CM3A 2I6IA 4HRFA 1P31A 1G7GA 3N2AA 2B3OA 4RDDA 1GG4A 2I3RA 4IKCA 2Y1OA 4JNBA 2JFFA 2PA5A 2UAGA 1YGUA 2H4KA 2Y68A 4GE2A 4JMKA 5J8RA 4QUMA 3QCEA 4BUCA 1XM2A 2B07A 4RI4A 2H4GA 2WGPA 3LJ8A 3EMUA 4QBWA 5BZXA 4RKKA 2QBQA 2AM2A 3RGOA 2BV5A 2MBCA 1BZHA 1OHDA 2R0BA 3QCBA 2NZ6A 3NRSA 2C7SA 3RO1A 1O5ZA 2Y2FA 1Q6TA 3PYZA 1R6HA 2OOQA 4GWFA 1OESA 3QCKA 1OEUA 1ONZA 4DGXA 2QCTA 1FQ1A 4HJPA 5KA8A 4C12A 3A5KA 3SR9A 2CJZA 2XPCA 2DXPA 1C84A 3QCFA 5BUGA 2VEXA 3ZM5A 1C88A 4BPCA 2F46A 4OHIA 2FJMA 2CM2A 5KADA 1C85A 2CM3A 1PH0A 3MOZA 4YR8B 4QDIA 4OHHA 2PBNA 3QCJA 2UUPA 1OHEA 3QCGA 5K24A 1NZ7A 5LXQB 1GWZA 1ZC0A 1FPZA 4KYQA 4RH5A 4NNDA 4Y14A 2CNGA 2HC1A 2AHSA 4QUNA 1MKPA 3AWGA 2B4OA 1EENA 1QXKA 1NL9A 3V0EA 1W78A 3D1QA 1WRMA 3RZ2A 1PTUA 2B4UA 2OUDA 1Q1MA 2J16A 2GC6A 2AM1A 2GCBA 1U25A 2B4PA 2CNFA 3HN7A 3M4UA 1XRIA 1OEOX 4ZN5A 1PXHA 4GFVA 1E0DA 3F41A 3V0FA 4KI9A 2M3VA 3EB1A 4NX8A 2NT7A 1GQYA 2A8BA 4C13A 5K23A 3ZM2A 2BGEA 5AWXA 2QDCA 4GS0A 3S4OA 4Y2EA 3O4SA 2JJDA 1I9TA 2CM7A 1D5RA 2I4EA 2CNIA
chains in the Genus database with same CATH topology
3QCLA 4JMJA 1PYNA 1KAVA 3QCDA 4OHEA 2SHPA 3U96A 2HVLA 1LYVA 5K9VA 2I5XA 2CM8A 5KA1A 3F9BA 4D3QA 1ZCKA 2I4GA 4R0TA 5K25A 1RXDA 1U26A 3H2XA 3O5XA 3ZM0A 4H34A 2P4DA 4PYHA 1XBOA 2Q47A 3EAXA 2CMCA 1QZ0A 5KA0A 3BM8A 1NWEA 2BGDA 1JF7A 1I9SA 2QBRA 2OZ5A 2QDPA 3BLUA 2VEYA 2I42A 1G4WR 4KYRA 1ECVA 1OHCA 5HDEA 2J17A 3V0JA 4RI5A 3BRHA 2CMAA 4JBCA 2I75A 3BLTA 5BX1A 2CMBA 2VEWA 1YWFA 5KACA 4R0SA 1I57A 1OEMX 2IMGA 5KA4A 1WCHA 2Y96A 3S3KA 2B4SA 5IBSA 2J16B 3QCHA 2VEVA 3AWFA 2CFVA 2C46A 1YTSA 2I4HA 5EHPA 1WAXA 5I6VA 1X24A 1JLNA 1P15A 2G59A 2NLKA 3O4TA 1OETA 1LARA 4D3PA 3B7OA 3CWEA 2GP0A 4PVGA 3O4UA 3MMJA 4GE6A 2HCMA 2H03A 4WU3A 2AZRA 3V0GA 3QKQA 5EHRA 1SUGA 1PTTA 1NO6A 4RH9A 1C86A 2PI7A 1FPRA 3SMEA 4GRYA 2I6PA 1G1FA 2BZLA 2F6FA 3QCMA 4ZI4A 1YGRA 1YPTA 1EEOA 1G1GA 5KAAA 2QCJA 2PSZA 3S4EA 1BZJA 2F6TA 3NMEA 2F71A 2H04A 1YZ4A 4DGPA 3I7ZA 4MBBA 4GE5A 1YTWA 4WOHA 5GTJA 1T48A 3QCCA 2ZN7A 4WU2A 2I6OA 2QDMA 4ERCA 4H1OA 4ZRTA 1LQFA 2HC2A 2QBSA 5KABA 5KA9A 2FJNA 4QBEA 1Q6PA 1M3GA 3I80A 1G7FA 1XXVA 3S3EA 2I3UA 2HNQA 2ZMMA 4OHLA 2NV5A 2F6ZA 1PTYA 5K9WA 1PTVA 5M43A 1YTNA 1ZZWA 3D1OA 4RHGA 2CNHA 3S3HA 3N0AA 2I6JA 1NNYA 2F70A 2F6VA 2H4VA 4R30A 1YFOA 4GFUA 3V0DA 1U24A 4YAAA 3QKPA 3D9CA 2F6YA 3D1HA 3RGQA 2A3KA 1VHRA 2ESBA 2B49A 1Q6SA 4NWFA 5KA2A 4QAPA 1V3AA 2Q05A 2PT0A 4HJQA 3F99A 2HB1A 3EU0A 3ZMQA 3V0IA 3AWEA 5BZZA 3O3LA 4AZ1A 3D42A 3I36A 1OEVA 2E0TA 2HNPA 2NTAA 4J51A 2HY3A 4D3RA 2HXPA 3V0HA 3ZM1A 2OC3A 1PA9A 1ZCLA 1BZCA 3F9AA 5K22A 2FH7A 2G6ZA 3OMHA 1G4US 3QCIA 4S0GA 4Z6BA 1NWLA 2I1YA 5IBMA 1L8KA 5KA3A 3EZZA 1C87A 2BIJA 3PS5A 2NT2A 2VEUA 1GFYA 1XXPA 1PA1A 4TVVA 1Q6JA 1A5YA 3OLRA 3A5JA 2P6XA 1RPMA 3QCNA 4ICZA 2QEPA 4B04A 3GXGA 1T49A 1T4JA 4GRZA 3ZM3A 4NWGA 3D44A 1Q6NA 1L8GA 1Q6MA 3ZMPA 2QBPA 4I8NA 2GWOA 2H02A 1C83A 4BJOA 1AAXA 2YDUA 4NYHA 2F6WA 3S3FA 1J4XA 1G1HA 5KA7A 2PQ5A 4OHDA 4WTYA 5MMZB 2GJTA 4QAHA 3F81A 1YN9A 3GXHA 2RF6A 1ONYA 3MOWA 1KAKA 3ZV2A 2CNEA 2I6MA 3CM3A 2I6IA 4HRFA 1G7GA 2B3OA 4RDDA 2I3RA 4IKCA 4JNBA 2PA5A 1YGUA 2H4KA 4GE2A 4JMKA 5J8RA 4QUMA 3QCEA 1XM2A 2B07A 4RI4A 2H4GA 2WGPA 3LJ8A 3EMUA 4QBWA 5BZXA 4RKKA 2QBQA 3RGOA 2BV5A 2MBCA 1BZHA 1OHDA 2R0BA 3QCBA 2NZ6A 2C7SA 3RO1A 2Y2FA 1Q6TA 1R6HA 2OOQA 4GWFA 1OESA 3QCKA 1OEUA 1ONZA 4DGXA 2QCTA 1FQ1A 4HJPA 5KA8A 3A5KA 3SR9A 2CJZA 2DXPA 1C84A 3QCFA 5BUGA 2VEXA 1C88A 4BPCA 2F46A 4OHIA 2FJMA 2CM2A 5KADA 1C85A 2CM3A 1PH0A 3MOZA 4YR8B 4OHHA 2PBNA 3QCJA 1OHEA 3QCGA 5K24A 1NZ7A 5LXQB 1GWZA 1ZC0A 1FPZA 4KYQA 4RH5A 4NNDA 4Y14A 2CNGA 2HC1A 2AHSA 4QUNA 1MKPA 3AWGA 2B4OA 1EENA 1QXKA 1NL9A 3V0EA 3D1QA 1WRMA 3RZ2A 1PTUA 2B4UA 2OUDA 1Q1MA 2J16A 1U25A 2B4PA 2CNFA 3M4UA 1XRIA 1OEOX 4ZN5A 1PXHA 4GFVA 3F41A 3V0FA 4KI9A 2M3VA 3EB1A 4NX8A 2NT7A 2A8BA 5K23A 3ZM2A 2BGEA 5AWXA 2QDCA 4GS0A 3S4OA 4Y2EA 3O4SA 2JJDA 1I9TA 2CM7A 1D5RA 2I4EA 2CNIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCL A;  4JMJ A;  1PYN A;  1KAV A;  3QCD A;  4OHE A;  2SHP A;  3U96 A;  2HVL A;  1LYV A;  5K9V A;  2I5X A;  2CM8 A;  5KA1 A;  3F9B A;  4D3Q A;  1ZCK A;  2I4G A;  4R0T A;  5K25 A;  1RXD A;  1U26 A;  3H2X A;  3O5X A;  3ZM0 A;  4H34 A;  2P4D A;  4PYH A;  1XBO A;  2Q47 A;  3EAX A;  2CMC A;  1QZ0 A;  5KA0 A;  3BM8 A;  1NWE A;  2BGD A;  1JF7 A;  1I9S A;  2QBR A;  2OZ5 A;  2QDP A;  3BLU A;  2VEY A;  2I42 A;  1G4W R;  4KYR A;  1ECV A;  1OHC A;  5HDE A;  2J17 A;  3V0J A;  4RI5 A;  3BRH A;  2CMA A;  4JBC A;  2I75 A;  3BLT A;  5BX1 A;  2CMB A;  2VEW A;  1YWF A;  5KAC A;  4R0S A;  1I57 A;  1OEM X;  2IMG A;  5KA4 A;  1WCH A;  2Y96 A;  3S3K A;  2B4S A;  5IBS A;  2J16 B;  3QCH A;  2VEV A;  3AWF A;  2CFV A;  2C46 A;  1YTS A;  2I4H A;  5EHP A;  1WAX A;  5I6V A;  1X24 A;  1JLN A;  1P15 A;  2G59 A;  2NLK A;  3O4T A;  1OET A;  1LAR A;  4D3P A;  3B7O A;  3CWE A;  2GP0 A;  4PVG A;  3O4U A;  3MMJ A;  4GE6 A;  2HCM A;  2H03 A;  4WU3 A;  2AZR A;  3V0G A;  3QKQ A;  5EHR A;  1SUG A;  1PTT A;  1NO6 A;  4RH9 A;  1C86 A;  2PI7 A;  1FPR A;  3SME A;  4GRY A;  2I6P A;  1G1F A;  2BZL A;  2F6F A;  3QCM A;  4ZI4 A;  1YGR A;  1YPT A;  1EEO A;  1G1G A;  5KAA A;  2QCJ A;  2PSZ A;  3S4E A;  1BZJ A;  2F6T A;  3NME A;  2F71 A;  2H04 A;  1YZ4 A;  4DGP A;  3I7Z A;  4MBB A;  4GE5 A;  1YTW A;  4WOH A;  5GTJ A;  1T48 A;  3QCC A;  2ZN7 A;  4WU2 A;  2I6O A;  2QDM A;  4ERC A;  4H1O A;  4ZRT A;  1LQF A;  2HC2 A;  2QBS A;  5KAB A;  5KA9 A;  2FJN A;  4QBE A;  1Q6P A;  1M3G A;  3I80 A;  1G7F A;  1XXV A;  3S3E A;  2I3U A;  2HNQ A;  2ZMM A;  4OHL A;  2NV5 A;  2F6Z A;  1PTY A;  5K9W A;  1PTV A;  5M43 A;  1YTN A;  1ZZW A;  3D1O A;  4RHG A;  2CNH A;  3S3H A;  3N0A A;  2I6J A;  1NNY A;  2F70 A;  2F6V A;  2H4V A;  4R30 A;  1YFO A;  4GFU A;  3V0D A;  1U24 A;  4YAA A;  3QKP A;  3D9C A;  2F6Y A;  3D1H A;  3RGQ A;  2A3K A;  1VHR A;  2ESB A;  2B49 A;  1Q6S A;  4NWF A;  5KA2 A;  4QAP A;  1V3A A;  2Q05 A;  2PT0 A;  4HJQ A;  3F99 A;  2HB1 A;  3EU0 A;  3ZMQ A;  3V0I A;  3AWE A;  5BZZ A;  3O3L A;  4AZ1 A;  3D42 A;  3I36 A;  1OEV A;  2E0T A;  2HNP A;  2NTA A;  4J51 A;  2HY3 A;  4D3R A;  2HXP A;  3V0H A;  3ZM1 A;  2OC3 A;  1PA9 A;  1ZCL A;  1BZC A;  3F9A A;  5K22 A;  2FH7 A;  2G6Z A;  3OMH A;  1G4U S;  3QCI A;  4S0G A;  4Z6B A;  1NWL A;  2I1Y A;  5IBM A;  1L8K A;  5KA3 A;  3EZZ A;  1C87 A;  2BIJ A;  3PS5 A;  2NT2 A;  2VEU A;  1GFY A;  1XXP A;  1PA1 A;  4TVV A;  1Q6J A;  1A5Y A;  3OLR A;  3A5J A;  2P6X A;  1RPM A;  3QCN A;  4ICZ A;  2QEP A;  4B04 A;  3GXG A;  1T49 A;  1T4J A;  4GRZ A;  3ZM3 A;  4NWG A;  3D44 A;  1Q6N A;  1L8G A;  1Q6M A;  3ZMP A;  2QBP A;  4I8N A;  2GWO A;  2H02 A;  1C83 A;  4BJO A;  1AAX A;  2YDU A;  4NYH A;  2F6W A;  3S3F A;  1J4X A;  1G1H A;  5KA7 A;  2PQ5 A;  4OHD A;  4WTY A;  5MMZ B;  2GJT A;  4QAH A;  3F81 A;  1YN9 A;  3GXH A;  2RF6 A;  1ONY A;  3MOW A;  1KAK A;  3ZV2 A;  2CNE A;  2I6M A;  3CM3 A;  2I6I A;  4HRF A;  1G7G A;  2B3O A;  4RDD A;  2I3R A;  4IKC A;  4JNB A;  2PA5 A;  1YGU A;  2H4K A;  4GE2 A;  4JMK A;  5J8R A;  4QUM A;  3QCE A;  1XM2 A;  2B07 A;  4RI4 A;  2H4G A;  2WGP A;  3LJ8 A;  3EMU A;  4QBW A;  5BZX A;  4RKK A;  2QBQ A;  3RGO A;  2BV5 A;  2MBC A;  1BZH A;  1OHD A;  2R0B A;  3QCB A;  2NZ6 A;  2C7S A;  3RO1 A;  2Y2F A;  1Q6T A;  1R6H A;  2OOQ A;  4GWF A;  1OES A;  3QCK A;  1OEU A;  1ONZ A;  4DGX A;  2QCT A;  1FQ1 A;  4HJP A;  5KA8 A;  3A5K A;  3SR9 A;  2CJZ A;  2DXP A;  1C84 A;  3QCF A;  5BUG A;  2VEX A;  1C88 A;  4BPC A;  2F46 A;  4OHI A;  2FJM A;  2CM2 A;  5KAD A;  1C85 A;  2CM3 A;  1PH0 A;  3MOZ A;  4YR8 B;  4OHH A;  2PBN A;  3QCJ A;  1OHE A;  3QCG A;  5K24 A;  1NZ7 A;  5LXQ B;  1GWZ A;  1ZC0 A;  1FPZ A;  4KYQ A;  4RH5 A;  4NND A;  4Y14 A;  2CNG A;  2HC1 A;  2AHS A;  4QUN A;  1MKP A;  3AWG A;  2B4O A;  1EEN A;  1QXK A;  1NL9 A;  3V0E A;  3D1Q A;  1WRM A;  3RZ2 A;  1PTU A;  2B4U A;  2OUD A;  1Q1M A;  2J16 A;  1U25 A;  2B4P A;  2CNF A;  3M4U A;  1XRI A;  1OEO X;  4ZN5 A;  1PXH A;  4GFV A;  3F41 A;  3V0F A;  4KI9 A;  2M3V A;  3EB1 A;  4NX8 A;  2NT7 A;  2A8B A;  5K23 A;  3ZM2 A;  2BGE A;  5AWX A;  2QDC A;  4GS0 A;  3S4O A;  4Y2E A;  3O4S A;  2JJD A;  1I9T A;  2CM7 A;  1D5R A;  2I4E A;  2CNI A; 
#chains in the Genus database with same CATH topology
 3QCL A;  4JMJ A;  1PYN A;  1KAV A;  3QCD A;  4OHE A;  2SHP A;  3U96 A;  2HVL A;  1LYV A;  5K9V A;  2I5X A;  2CM8 A;  5KA1 A;  3F9B A;  4D3Q A;  1ZCK A;  2I4G A;  4R0T A;  5K25 A;  1RXD A;  1U26 A;  3H2X A;  3O5X A;  3ZM0 A;  1FGS A;  4H34 A;  2P4D A;  4PYH A;  1XBO A;  2JFG A;  2Q47 A;  3EAX A;  2CMC A;  1QZ0 A;  2XJA A;  5KA0 A;  3BM8 A;  1NWE A;  2BGD A;  1JF7 A;  1I9S A;  2QBR A;  2OZ5 A;  2QDP A;  3BLU A;  2VEY A;  2I42 A;  1G4W R;  4KYR A;  1ECV A;  1OHC A;  5HDE A;  2J17 A;  3V0J A;  4RI5 A;  3BRH A;  2CMA A;  4JBC A;  2I75 A;  3BLT A;  4CVL A;  2CMB A;  5BX1 A;  2VEW A;  3LK7 A;  1YWF A;  5KAC A;  4R0S A;  2F00 A;  1I57 A;  1OEM X;  2IMG A;  5KA4 A;  1WCH A;  2Y96 A;  3S3K A;  1GQQ A;  2B4S A;  5IBS A;  1EEH A;  2J16 B;  3QCH A;  2VEV A;  3AWF A;  2CFV A;  2C46 A;  1YTS A;  2I4H A;  2VOR A;  5EHP A;  1WAX A;  5I6V A;  1X24 A;  1JLN A;  1P15 A;  2G59 A;  2NLK A;  2VOS A;  3O4T A;  1OET A;  1LAR A;  4HV4 A;  4D3P A;  3B7O A;  3CWE A;  2GP0 A;  3ZM6 A;  4PVG A;  3O4U A;  2X5O A;  3MMJ A;  2HCM A;  4GE6 A;  2H03 A;  4WU3 A;  2AZR A;  3V0G A;  3QKQ A;  5EHR A;  1SUG A;  1PTT A;  4CVK A;  1NO6 A;  1W7K A;  4RH9 A;  1C86 A;  2PI7 A;  1FPR A;  5A5E A;  3SME A;  4GRY A;  2I6P A;  1G1F A;  2BZL A;  2F6F A;  3QCM A;  4ZI4 A;  1YGR A;  1YPT A;  1EEO A;  2VTD A;  1G1G A;  5KAA A;  2QCJ A;  2PSZ A;  3S4E A;  1BZJ A;  2JFH A;  2F6T A;  3NME A;  2F71 A;  2H04 A;  1YZ4 A;  4DGP A;  3I7Z A;  4MBB A;  4GE5 A;  1YTW A;  4WOH A;  5GTJ A;  1T48 A;  3MVN A;  3QCC A;  1J6U A;  2ZN7 A;  4WU2 A;  2I6O A;  5A5F A;  2QDM A;  4ERC A;  4H1O A;  4ZRT A;  1LQF A;  2HC2 A;  2QBS A;  5KAB A;  5KA9 A;  2FJN A;  4QBE A;  1Q6P A;  1M3G A;  3I80 A;  1G7F A;  1XXV A;  1JBV A;  3S3E A;  2I3U A;  2HNQ A;  2ZMM A;  4OHL A;  2NV5 A;  2F6Z A;  1PTY A;  5K9W A;  1PTV A;  5M43 A;  1YTN A;  1ZZW A;  3D1O A;  4RHG A;  2CNH A;  4BUB A;  2VTE A;  3S3H A;  3ZL8 A;  3N0A A;  2I6J A;  2GC5 A;  1NNY A;  2F70 A;  2F6V A;  2H4V A;  4R30 A;  1JBW A;  1YFO A;  4GFU A;  3V0D A;  2WJP A;  1U24 A;  4YAA A;  3QKP A;  3D9C A;  2F6Y A;  3D1H A;  3RGQ A;  2A3K A;  1VHR A;  2ESB A;  2B49 A;  1Q6S A;  4NWF A;  5KA2 A;  4QAP A;  1V3A A;  4QF5 A;  2Q05 A;  2PT0 A;  4HJQ A;  3F99 A;  2HB1 A;  2WTZ A;  3EU0 A;  3ZMQ A;  3V0I A;  3AWE A;  5BZZ A;  1UAG A;  3O3L A;  4AZ1 A;  3D42 A;  3I36 A;  1OEV A;  2E0T A;  2HNP A;  2NTA A;  4J51 A;  1P3D A;  2HY3 A;  4D3R A;  2HXP A;  3V0H A;  3ZM1 A;  2OC3 A;  1PA9 A;  1ZCL A;  1BZC A;  3F9A A;  5K22 A;  2FH7 A;  2G6Z A;  3OMH A;  1G4U S;  3QCI A;  4CVM A;  4S0G A;  4Z6B A;  1NWL A;  2Y67 A;  2I1Y A;  5IBM A;  1L8K A;  5KA3 A;  3EZZ A;  3UAG A;  1C87 A;  2BIJ A;  3PS5 A;  2NT2 A;  2VEU A;  1GFY A;  1XXP A;  1PA1 A;  4TVV A;  1Q6J A;  1A5Y A;  3OLR A;  3A5J A;  2P6X A;  1RPM A;  2UUO A;  3QCN A;  4ICZ A;  2QEP A;  4B04 A;  3GXG A;  1T49 A;  4ZIY A;  1T4J A;  4GRZ A;  3ZM3 A;  4NWG A;  3D44 A;  1Q6N A;  1E8C A;  1L8G A;  1Q6M A;  3ZMP A;  2Y66 A;  2QBP A;  4I8N A;  2GWO A;  2H02 A;  1C83 A;  4BJO A;  1AAX A;  4UAG A;  2YDU A;  2GCA A;  4NYH A;  2F6W A;  3S3F A;  1J4X A;  1G1H A;  3QCZ A;  5KA7 A;  2PQ5 A;  4OHD A;  4WTY A;  5MMZ B;  2GJT A;  4QAH A;  1YN9 A;  3F81 A;  3GXH A;  2RF6 A;  1ONY A;  3MOW A;  1KAK A;  3ZV2 A;  2CNE A;  2I6M A;  3CM3 A;  2I6I A;  4HRF A;  1P31 A;  1G7G A;  3N2A A;  2B3O A;  4RDD A;  1GG4 A;  2I3R A;  4IKC A;  2Y1O A;  4JNB A;  2JFF A;  2PA5 A;  2UAG A;  1YGU A;  2H4K A;  2Y68 A;  4GE2 A;  4JMK A;  5J8R A;  4QUM A;  3QCE A;  4BUC A;  1XM2 A;  2B07 A;  4RI4 A;  2H4G A;  2WGP A;  3LJ8 A;  3EMU A;  4QBW A;  5BZX A;  4RKK A;  2QBQ A;  2AM2 A;  3RGO A;  2BV5 A;  2MBC A;  1BZH A;  1OHD A;  2R0B A;  3QCB A;  2NZ6 A;  3NRS A;  2C7S A;  3RO1 A;  1O5Z A;  2Y2F A;  1Q6T A;  3PYZ A;  1R6H A;  2OOQ A;  4GWF A;  1OES A;  3QCK A;  1OEU A;  1ONZ A;  4DGX A;  2QCT A;  1FQ1 A;  4HJP A;  5KA8 A;  4C12 A;  3A5K A;  3SR9 A;  2CJZ A;  2XPC A;  2DXP A;  1C84 A;  3QCF A;  5BUG A;  2VEX A;  3ZM5 A;  1C88 A;  4BPC A;  2F46 A;  4OHI A;  2FJM A;  2CM2 A;  5KAD A;  1C85 A;  2CM3 A;  1PH0 A;  3MOZ A;  4YR8 B;  4QDI A;  4OHH A;  2PBN A;  3QCJ A;  2UUP A;  1OHE A;  3QCG A;  5K24 A;  1NZ7 A;  5LXQ B;  1GWZ A;  1ZC0 A;  1FPZ A;  4KYQ A;  4RH5 A;  4NND A;  4Y14 A;  2CNG A;  2HC1 A;  2AHS A;  4QUN A;  1MKP A;  3AWG A;  2B4O A;  1EEN A;  1QXK A;  1NL9 A;  3V0E A;  1W78 A;  3D1Q A;  1WRM A;  3RZ2 A;  1PTU A;  2B4U A;  2OUD A;  1Q1M A;  2J16 A;  2GC6 A;  2AM1 A;  2GCB A;  1U25 A;  2B4P A;  2CNF A;  3HN7 A;  3M4U A;  1XRI A;  1OEO X;  4ZN5 A;  1PXH A;  4GFV A;  1E0D A;  3F41 A;  3V0F A;  4KI9 A;  2M3V A;  3EB1 A;  4NX8 A;  2NT7 A;  1GQY A;  2A8B A;  4C13 A;  5K23 A;  3ZM2 A;  2BGE A;  5AWX A;  2QDC A;  4GS0 A;  3S4O A;  4Y2E A;  3O4S A;  2JJD A;  1I9T A;  2CM7 A;  1D5R A;  2I4E A;  2CNI A; 
#chains in the Genus database with same CATH homology
 3QCL A;  4JMJ A;  1PYN A;  1KAV A;  3QCD A;  4OHE A;  2SHP A;  3U96 A;  2HVL A;  1LYV A;  5K9V A;  2I5X A;  2CM8 A;  5KA1 A;  3F9B A;  4D3Q A;  1ZCK A;  2I4G A;  4R0T A;  5K25 A;  1RXD A;  1U26 A;  3H2X A;  3O5X A;  3ZM0 A;  4H34 A;  2P4D A;  4PYH A;  1XBO A;  2Q47 A;  3EAX A;  2CMC A;  1QZ0 A;  5KA0 A;  3BM8 A;  1NWE A;  2BGD A;  1JF7 A;  1I9S A;  2QBR A;  2OZ5 A;  2QDP A;  3BLU A;  2VEY A;  2I42 A;  1G4W R;  4KYR A;  1ECV A;  1OHC A;  5HDE A;  2J17 A;  3V0J A;  4RI5 A;  3BRH A;  2CMA A;  4JBC A;  2I75 A;  3BLT A;  5BX1 A;  2CMB A;  2VEW A;  1YWF A;  5KAC A;  4R0S A;  1I57 A;  1OEM X;  2IMG A;  5KA4 A;  1WCH A;  2Y96 A;  3S3K A;  2B4S A;  5IBS A;  2J16 B;  3QCH A;  2VEV A;  3AWF A;  2CFV A;  2C46 A;  1YTS A;  2I4H A;  5EHP A;  1WAX A;  5I6V A;  1X24 A;  1JLN A;  1P15 A;  2G59 A;  2NLK A;  3O4T A;  1OET A;  1LAR A;  4D3P A;  3B7O A;  3CWE A;  2GP0 A;  4PVG A;  3O4U A;  3MMJ A;  4GE6 A;  2HCM A;  2H03 A;  4WU3 A;  2AZR A;  3V0G A;  3QKQ A;  5EHR A;  1SUG A;  1PTT A;  1NO6 A;  4RH9 A;  1C86 A;  2PI7 A;  1FPR A;  3SME A;  4GRY A;  2I6P A;  1G1F A;  2BZL A;  2F6F A;  3QCM A;  4ZI4 A;  1YGR A;  1YPT A;  1EEO A;  1G1G A;  5KAA A;  2QCJ A;  2PSZ A;  3S4E A;  1BZJ A;  2F6T A;  3NME A;  2F71 A;  2H04 A;  1YZ4 A;  4DGP A;  3I7Z A;  4MBB A;  4GE5 A;  1YTW A;  4WOH A;  5GTJ A;  1T48 A;  3QCC A;  2ZN7 A;  4WU2 A;  2I6O A;  2QDM A;  4ERC A;  4H1O A;  4ZRT A;  1LQF A;  2HC2 A;  2QBS A;  5KAB A;  5KA9 A;  2FJN A;  4QBE A;  1Q6P A;  1M3G A;  3I80 A;  1G7F A;  1XXV A;  3S3E A;  2I3U A;  2HNQ A;  2ZMM A;  4OHL A;  2NV5 A;  2F6Z A;  1PTY A;  5K9W A;  1PTV A;  5M43 A;  1YTN A;  1ZZW A;  3D1O A;  4RHG A;  2CNH A;  3S3H A;  3N0A A;  2I6J A;  1NNY A;  2F70 A;  2F6V A;  2H4V A;  4R30 A;  1YFO A;  4GFU A;  3V0D A;  1U24 A;  4YAA A;  3QKP A;  3D9C A;  2F6Y A;  3D1H A;  3RGQ A;  2A3K A;  1VHR A;  2ESB A;  2B49 A;  1Q6S A;  4NWF A;  5KA2 A;  4QAP A;  1V3A A;  2Q05 A;  2PT0 A;  4HJQ A;  3F99 A;  2HB1 A;  3EU0 A;  3ZMQ A;  3V0I A;  3AWE A;  5BZZ A;  3O3L A;  4AZ1 A;  3D42 A;  3I36 A;  1OEV A;  2E0T A;  2HNP A;  2NTA A;  4J51 A;  2HY3 A;  4D3R A;  2HXP A;  3V0H A;  3ZM1 A;  2OC3 A;  1PA9 A;  1ZCL A;  1BZC A;  3F9A A;  5K22 A;  2FH7 A;  2G6Z A;  3OMH A;  1G4U S;  3QCI A;  4S0G A;  4Z6B A;  1NWL A;  2I1Y A;  5IBM A;  1L8K A;  5KA3 A;  3EZZ A;  1C87 A;  2BIJ A;  3PS5 A;  2NT2 A;  2VEU A;  1GFY A;  1XXP A;  1PA1 A;  4TVV A;  1Q6J A;  1A5Y A;  3OLR A;  3A5J A;  2P6X A;  1RPM A;  3QCN A;  4ICZ A;  2QEP A;  4B04 A;  3GXG A;  1T49 A;  1T4J A;  4GRZ A;  3ZM3 A;  4NWG A;  3D44 A;  1Q6N A;  1L8G A;  1Q6M A;  3ZMP A;  2QBP A;  4I8N A;  2GWO A;  2H02 A;  1C83 A;  4BJO A;  1AAX A;  2YDU A;  4NYH A;  2F6W A;  3S3F A;  1J4X A;  1G1H A;  5KA7 A;  2PQ5 A;  4OHD A;  4WTY A;  5MMZ B;  2GJT A;  4QAH A;  3F81 A;  1YN9 A;  3GXH A;  2RF6 A;  1ONY A;  3MOW A;  1KAK A;  3ZV2 A;  2CNE A;  2I6M A;  3CM3 A;  2I6I A;  4HRF A;  1G7G A;  2B3O A;  4RDD A;  2I3R A;  4IKC A;  4JNB A;  2PA5 A;  1YGU A;  2H4K A;  4GE2 A;  4JMK A;  5J8R A;  4QUM A;  3QCE A;  1XM2 A;  2B07 A;  4RI4 A;  2H4G A;  2WGP A;  3LJ8 A;  3EMU A;  4QBW A;  5BZX A;  4RKK A;  2QBQ A;  3RGO A;  2BV5 A;  2MBC A;  1BZH A;  1OHD A;  2R0B A;  3QCB A;  2NZ6 A;  2C7S A;  3RO1 A;  2Y2F A;  1Q6T A;  1R6H A;  2OOQ A;  4GWF A;  1OES A;  3QCK A;  1OEU A;  1ONZ A;  4DGX A;  2QCT A;  1FQ1 A;  4HJP A;  5KA8 A;  3A5K A;  3SR9 A;  2CJZ A;  2DXP A;  1C84 A;  3QCF A;  5BUG A;  2VEX A;  1C88 A;  4BPC A;  2F46 A;  4OHI A;  2FJM A;  2CM2 A;  5KAD A;  1C85 A;  2CM3 A;  1PH0 A;  3MOZ A;  4YR8 B;  4OHH A;  2PBN A;  3QCJ A;  1OHE A;  3QCG A;  5K24 A;  1NZ7 A;  5LXQ B;  1GWZ A;  1ZC0 A;  1FPZ A;  4KYQ A;  4RH5 A;  4NND A;  4Y14 A;  2CNG A;  2HC1 A;  2AHS A;  4QUN A;  1MKP A;  3AWG A;  2B4O A;  1EEN A;  1QXK A;  1NL9 A;  3V0E A;  3D1Q A;  1WRM A;  3RZ2 A;  1PTU A;  2B4U A;  2OUD A;  1Q1M A;  2J16 A;  1U25 A;  2B4P A;  2CNF A;  3M4U A;  1XRI A;  1OEO X;  4ZN5 A;  1PXH A;  4GFV A;  3F41 A;  3V0F A;  4KI9 A;  2M3V A;  3EB1 A;  4NX8 A;  2NT7 A;  2A8B A;  5K23 A;  3ZM2 A;  2BGE A;  5AWX A;  2QDC A;  4GS0 A;  3S4O A;  4Y2E A;  3O4S A;  2JJD A;  1I9T A;  2CM7 A;  1D5R A;  2I4E A;  2CNI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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