5KA3A

Protein tyrosine phosphatase 1b yaya (y152a, y153a) mutant in complex with tcs401, closed state
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
295
structure length
295
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSAATVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 106
structure length 295
sequence length 295
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka3A00
1OEMX 2M3VA 2OC3A 3MMJA 5KA2A 3PS5A 3BLUA 3V0JA 2NT7A 1NO6A 3S3EA 1Q6NA 4PVGA 3O5XA 2CNIA 2HB1A 4J51A 2C46A 2VEVA 1NWLA 2I6JA 3ZM1A 4GE2A 2HXPA 4TVVA 2HC2A 1XXPA 1JF7A 1PTVA 1QXKA 1P15A 1WRMA 5KA4A 4OHIA 3F81A 3I36A 3B7OA 1G7FA 5KADA 3V0DA 1PA1A 2I6PA 2H02A 1FPRA 1D5RA 3NMEA 3ZMPA 1X24A 3QCDA 2OOQA 2QBPA 4WU2A 5BZXA 1ZCKA 1NNYA 1EEOA 3MOZA 1OESA 5K9WA 2FJMA 5KA1A 1YTWA 2QDCA 2F6WA 3S3HA 4Z6BA 4RH9A 4D3RA 3S4OA 1OHCA 2I4HA 2CNFA 2CM3A 1LQFA 2G6ZA 2FJNA 3LJ8A 2BZLA 1I57A 2J16A 2MBCA 2A8BA 4I8NA 4D3PA 1YN9A 2BGEA 3QCFA 3V0HA 3A5JA 5K23A 5HDEA 2QBRA 4ICZA 3AWGA 4DGXA 5J8RA 4QUMA 2VEXA 4RKKA 1RXDA 5BUGA 1ONZA 4MBBA 1RPMA 1G4US 5KA8A 1Q6SA 2B07A 4OHLA 2Q47A 2BV5A 1G1FA 4YR8B 1C88A 2I4EA 5M43A 3AWEA 4ZN5A 3QCGA 1KAKA 1VHRA 3O4UA 4BJOA 5KA3A 2CMAA 1ZC0A 3SMEA 2F6YA 1FQ1A 2I6OA 4GWFA 3D44A 1Q1MA 2FH7A 1T49A 1YZ4A 3A5KA 3SR9A 1U24A 2SHPA 3V0IA 4QBWA 3QCKA 3EU0A 4RH5A 2IMGA 4JNBA 5AWXA 3CWEA 1LYVA 2NLKA 1Q6TA 1YFOA 4WU3A 1YPTA 2F6FA 2P6XA 3EAXA 2ZN7A 4WOHA 1ZZWA 1OHDA 4JMKA 3QKQA 2BGDA 5K25A 1BZHA 2H03A 2QBSA 3F41A 1JLNA 1OEOX 3QCCA 3QCMA 3S3KA 2CM2A 3GXGA 4HJPA 3OMHA 4S0GA 4QUNA 5KABA 3F9BA 3O3LA 3O4TA 1PYNA 4Y14A 4GRYA 1L8KA 2I75A 4OHDA 1PH0A 2PQ5A 5I6VA 4HJQA 1BZJA 4ERCA 3BLTA 1QZ0A 2VEYA 1EENA 1BZCA 1YGUA 2F71A 3QCHA 2RF6A 2VEUA 2HY3A 1C84A 2B49A 3ZM0A 1C83A 2P4DA 4GE5A 1PA9A 4RI5A 4B04A 4NNDA 4R0TA 4H34A 4GE6A 2I42A 1PTUA 1OHEA 5KAAA 1R6HA 1XM2A 1NWEA 2I6IA 4PYHA 1Q6JA 1C87A 2I5XA 2B4OA 1ZCLA 4NWFA 2ZMMA 1AAXA 3N0AA 1YWFA 4RDDA 1I9SA 1MKPA 1XRIA 3AWFA 1G1HA 3QCNA 3O4SA 4R0SA 2B4UA 3CM3A 2PT0A 2PI7A 1L8GA 2QBQA 3QKPA 2J17A 3D42A 3F99A 1KAVA 1GFYA 2H4VA 1WCHA 1XXVA 1G7GA 1NZ7A 2J16B 3OLRA 1PTTA 2PA5A 2QEPA 1ECVA 4YAAA 1WAXA 1I9TA 2QCTA 2F46A 2H04A 4NYHA 2OZ5A 2BIJA 2CNEA 4JBCA 2NT2A 3RO1A 3S4EA 5IBMA 1ONYA 1SUGA 1V3AA 2CM7A 1M3GA 1NL9A 3QCLA 2WGPA 2CM8A 3H2XA 2H4KA 1A5YA 1C85A 4Y2EA 3D1HA 3RGOA 3U96A 2F6VA 3BM8A 2YDUA 3EMUA 3RZ2A 3ZM3A 1G4WR 3QCIA 1PTYA 2F6ZA 2QDPA 4GRZA 1J4XA 2HVLA 5IBSA 2HNQA 2CNHA 5BZZA 1Q6PA 5GTJA 5KA9A 4D3QA 2A3KA 2CMCA 4QAHA 2PSZA 3I80A 1U26A 1OETA 2ESBA 5EHPA 1Q6MA 4KYQA 2I4GA 3QCBA 3V0EA 2JJDA 2NZ6A 3D1QA 1GWZA 5KA0A 1U25A 2CJZA 2F70A 2DXPA 3I7ZA 1YTNA 3M4UA 3ZM2A 3MOWA 2QCJA 4GS0A 4AZ1A 1T48A 2Y96A 3V0GA 3GXHA 2R0BA 2OUDA 2E0TA 3F9AA 4OHHA 4KI9A 5K22A 2GJTA 2NTAA 4NWGA 3EB1A 4GFVA 2F6TA 2H4GA 4HRFA 2AZRA 1FPZA 1XBOA 3D9CA 4NX8A 4WTYA 5KA7A 4JMJA 2NV5A 3ZV2A 1LARA 4KYRA 2HNPA 3EZZA 2AHSA 2GWOA 1PXHA 2VEWA 5LXQB 2I3RA 4BPCA 4RHGA 1OEVA 2B4SA 1OEUA 1G1GA 2CNGA 4DGPA 2CMBA 2CFVA 2C7SA 2I6MA 4R30A 4RI4A 5K9VA 4H1OA 4OHEA 4GFUA 2GP0A 3QCEA 3BRHA 2QDMA 5KACA 2HC1A 4QAPA 4IKCA 2G59A 1YGRA 2B4PA 2I3UA 1T4JA 2HCMA 2Q05A 5MMZB 3QCJA 2B3OA 1C86A 3RGQA 5EHRA 3V0FA 5BX1A 4ZI4A 3S3FA 3ZMQA 3D1OA 2Y2FA 4ZRTA 5K24A 2I1YA 1YTSA 4QBEA 2PBNA
chains in the Genus database with same CATH superfamily
1OEMX 2M3VA 2OC3A 3MMJA 5KA2A 3PS5A 3BLUA 3V0JA 2NT7A 1NO6A 3S3EA 1Q6NA 1J6UA 4PVGA 3O5XA 2CNIA 2HB1A 4J51A 2C46A 1W7KA 2VEVA 1NWLA 2I6JA 3ZM1A 4GE2A 2UAGA 2HXPA 4TVVA 2HC2A 1XXPA 1JF7A 2VTDA 1PTVA 1QXKA 1P15A 1WRMA 5KA4A 4OHIA 3F81A 5A5FA 4CVMA 3I36A 3B7OA 1G7FA 5KADA 3V0DA 1P3DA 1PA1A 2I6PA 2H02A 1FPRA 1D5RA 3NMEA 3ZMPA 1X24A 3QCDA 2OOQA 2QBPA 4WU2A 5BZXA 1ZCKA 1E0DA 1NNYA 1EEOA 3MOZA 1OESA 2Y66A 5K9WA 2FJMA 5KA1A 1YTWA 2QDCA 2F6WA 3S3HA 4Z6BA 4RH9A 4D3RA 3S4OA 1OHCA 2I4HA 2CNFA 2CM3A 1LQFA 2G6ZA 2FJNA 1GQQA 3LJ8A 2BZLA 2VOSA 1I57A 2J16A 2MBCA 2A8BA 4I8NA 4D3PA 1YN9A 2BGEA 3QCFA 1GG4A 3V0HA 3UAGA 3A5JA 5K23A 5HDEA 4BUCA 2QBRA 4ICZA 3AWGA 1E8CA 2XPCA 4DGXA 5J8RA 4QUMA 2VEXA 4RKKA 1RXDA 5BUGA 2GCBA 1ONZA 4MBBA 1RPMA 1G4US 5KA8A 1Q6SA 2B07A 3ZL8A 4OHLA 2Q47A 1O5ZA 2BV5A 1G1FA 3QCZA 4YR8B 1C88A 2I4EA 5M43A 3AWEA 4ZN5A 1GQYA 3QCGA 1KAKA 1VHRA 3O4UA 4BJOA 5KA3A 2CMAA 1ZC0A 2GCAA 3SMEA 2F6YA 1FQ1A 2I6OA 4GWFA 3D44A 1Q1MA 2FH7A 1T49A 1YZ4A 3A5KA 3SR9A 4HV4A 1U24A 2SHPA 3V0IA 4QBWA 3HN7A 3PYZA 3QCKA 3EU0A 4RH5A 2IMGA 4JNBA 2VORA 1W78A 5AWXA 3CWEA 1LYVA 2NLKA 4QDIA 1Q6TA 2VTEA 1YFOA 4WU3A 1YPTA 2F6FA 2P6XA 3EAXA 2ZN7A 4WOHA 1ZZWA 1OHDA 4JMKA 4C12A 3QKQA 2BGDA 5K25A 4BUBA 1BZHA 2H03A 2QBSA 3F41A 1JLNA 2Y1OA 1OEOX 3QCCA 3QCMA 3S3KA 2CM2A 3GXGA 4HJPA 3OMHA 4S0GA 4QUNA 5KABA 3F9BA 3O3LA 3O4TA 1PYNA 4Y14A 4GRYA 1L8KA 2I75A 3N2AA 4OHDA 1PH0A 2PQ5A 5I6VA 4HJQA 1BZJA 4ERCA 3BLTA 1QZ0A 2VEYA 1BZCA 1EENA 1YGUA 2F71A 3QCHA 2RF6A 2VEUA 2HY3A 1C84A 2B49A 3LK7A 3ZM0A 1C83A 2P4DA 4GE5A 4CVLA 1PA9A 4RI5A 4B04A 2JFGA 4NNDA 4R0TA 4H34A 4GE6A 2I42A 1PTUA 1OHEA 5KAAA 1R6HA 1XM2A 1NWEA 2I6IA 2WJPA 4UAGA 4PYHA 1Q6JA 1C87A 2I5XA 2B4OA 1ZCLA 4NWFA 2ZMMA 1AAXA 3N0AA 5A5EA 1YWFA 4RDDA 1I9SA 1MKPA 1XRIA 3AWFA 1G1HA 3QCNA 3O4SA 4R0SA 2B4UA 3CM3A 2PT0A 2PI7A 1L8GA 2QBQA 3QKPA 2J17A 3D42A 3F99A 1KAVA 1GFYA 2H4VA 1WCHA 1XXVA 1G7GA 1NZ7A 2J16B 3OLRA 1PTTA 2PA5A 2QEPA 1ECVA 4YAAA 4CVKA 1WAXA 2XJAA 1I9TA 2QCTA 2F46A 2H04A 4NYHA 2OZ5A 2BIJA 2JFHA 2CNEA 2WTZA 4JBCA 2NT2A 3RO1A 3S4EA 5IBMA 2GC6A 1ONYA 3MVNA 1SUGA 1V3AA 2CM7A 2Y68A 4ZIYA 1M3GA 1NL9A 3QCLA 2WGPA 2CM8A 2UUOA 3H2XA 2H4KA 1A5YA 1C85A 3NRSA 3D1HA 4Y2EA 3RGOA 3U96A 2AM1A 2F6VA 3BM8A 1EEHA 2Y67A 2YDUA 3EMUA 3RZ2A 3ZM3A 1G4WR 3QCIA 1PTYA 2F6ZA 2QDPA 4GRZA 1J4XA 2HVLA 5IBSA 2HNQA 2JFFA 2CNHA 5BZZA 1Q6PA 2X5OA 5GTJA 5KA9A 4D3QA 2A3KA 2CMCA 2AM2A 4QAHA 4QF5A 2PSZA 3I80A 1U26A 1OETA 2ESBA 2UUPA 5EHPA 1Q6MA 4KYQA 2I4GA 3QCBA 3V0EA 2JJDA 2NZ6A 3D1QA 1GWZA 4C13A 5KA0A 1JBWA 1U25A 2CJZA 2F70A 2DXPA 3I7ZA 1YTNA 3M4UA 3ZM2A 3MOWA 2QCJA 4GS0A 4AZ1A 1T48A 2Y96A 1P31A 3V0GA 3GXHA 2R0BA 2OUDA 2E0TA 3F9AA 4OHHA 4KI9A 5K22A 2GC5A 2GJTA 2NTAA 4NWGA 3EB1A 4GFVA 2F00A 2F6TA 2H4GA 4HRFA 2AZRA 1FPZA 1XBOA 3D9CA 4NX8A 4WTYA 5KA7A 4JMJA 2NV5A 3ZV2A 1LARA 4KYRA 2HNPA 3EZZA 2AHSA 2GWOA 1PXHA 2VEWA 5LXQB 2I3RA 4BPCA 4RHGA 1UAGA 1OEVA 2B4SA 1OEUA 1G1GA 2CNGA 4DGPA 3ZM5A 2CMBA 2CFVA 2C7SA 2I6MA 4R30A 4RI4A 5K9VA 4H1OA 4OHEA 4GFUA 2GP0A 3QCEA 3BRHA 2QDMA 3ZM6A 5KACA 2HC1A 4QAPA 4IKCA 2G59A 1YGRA 2B4PA 2I3UA 1T4JA 2HCMA 2Q05A 5MMZB 3QCJA 2B3OA 1C86A 3RGQA 5EHRA 3V0FA 5BX1A 1JBVA 4ZI4A 1FGSA 3S3FA 3ZMQA 3D1OA 2Y2FA 4ZRTA 5K24A 2I1YA 1YTSA 4QBEA 2PBNA
chains in the Genus database with same CATH topology
1OEMX 2M3VA 2OC3A 3MMJA 5KA2A 3PS5A 3BLUA 3V0JA 2NT7A 1NO6A 3S3EA 1Q6NA 4PVGA 3O5XA 2CNIA 2HB1A 4J51A 2C46A 2VEVA 1NWLA 2I6JA 3ZM1A 4GE2A 2HXPA 4TVVA 2HC2A 1XXPA 1JF7A 1PTVA 1QXKA 1P15A 1WRMA 5KA4A 4OHIA 3F81A 3I36A 3B7OA 1G7FA 5KADA 3V0DA 1PA1A 2I6PA 2H02A 1FPRA 1D5RA 3NMEA 3ZMPA 1X24A 3QCDA 2OOQA 2QBPA 4WU2A 5BZXA 1ZCKA 1NNYA 1EEOA 3MOZA 1OESA 5K9WA 2FJMA 5KA1A 1YTWA 2QDCA 2F6WA 3S3HA 4Z6BA 4RH9A 4D3RA 3S4OA 1OHCA 2I4HA 2CNFA 2CM3A 1LQFA 2G6ZA 2FJNA 3LJ8A 2BZLA 1I57A 2J16A 2MBCA 2A8BA 4I8NA 4D3PA 1YN9A 2BGEA 3QCFA 3V0HA 3A5JA 5K23A 5HDEA 2QBRA 4ICZA 3AWGA 4DGXA 5J8RA 4QUMA 2VEXA 4RKKA 1RXDA 5BUGA 1ONZA 4MBBA 1RPMA 1G4US 5KA8A 1Q6SA 2B07A 4OHLA 2Q47A 2BV5A 1G1FA 4YR8B 1C88A 2I4EA 5M43A 3AWEA 4ZN5A 3QCGA 1KAKA 1VHRA 3O4UA 4BJOA 5KA3A 2CMAA 1ZC0A 3SMEA 2F6YA 1FQ1A 2I6OA 4GWFA 3D44A 1Q1MA 2FH7A 1T49A 1YZ4A 3A5KA 3SR9A 1U24A 2SHPA 3V0IA 4QBWA 3QCKA 3EU0A 4RH5A 2IMGA 4JNBA 5AWXA 3CWEA 1LYVA 2NLKA 1Q6TA 1YFOA 4WU3A 1YPTA 2F6FA 2P6XA 3EAXA 2ZN7A 4WOHA 1ZZWA 1OHDA 4JMKA 3QKQA 2BGDA 5K25A 1BZHA 2H03A 2QBSA 3F41A 1JLNA 1OEOX 3QCCA 3QCMA 3S3KA 2CM2A 3GXGA 4HJPA 3OMHA 4S0GA 4QUNA 5KABA 3F9BA 3O3LA 3O4TA 1PYNA 4Y14A 4GRYA 1L8KA 2I75A 4OHDA 1PH0A 2PQ5A 5I6VA 4HJQA 1BZJA 4ERCA 3BLTA 1QZ0A 2VEYA 1EENA 1BZCA 1YGUA 2F71A 3QCHA 2RF6A 2VEUA 2HY3A 1C84A 2B49A 3ZM0A 1C83A 2P4DA 4GE5A 1PA9A 4RI5A 4B04A 4NNDA 4R0TA 4H34A 4GE6A 2I42A 1PTUA 1OHEA 5KAAA 1R6HA 1XM2A 1NWEA 2I6IA 4PYHA 1Q6JA 1C87A 2I5XA 2B4OA 1ZCLA 4NWFA 2ZMMA 1AAXA 3N0AA 1YWFA 4RDDA 1I9SA 1MKPA 1XRIA 3AWFA 1G1HA 3QCNA 3O4SA 4R0SA 2B4UA 3CM3A 2PT0A 2PI7A 1L8GA 2QBQA 3QKPA 2J17A 3D42A 3F99A 1KAVA 1GFYA 2H4VA 1WCHA 1XXVA 1G7GA 1NZ7A 2J16B 3OLRA 1PTTA 2PA5A 2QEPA 1ECVA 4YAAA 1WAXA 1I9TA 2QCTA 2F46A 2H04A 4NYHA 2OZ5A 2BIJA 2CNEA 4JBCA 2NT2A 3RO1A 3S4EA 5IBMA 1ONYA 1SUGA 1V3AA 2CM7A 1M3GA 1NL9A 3QCLA 2WGPA 2CM8A 3H2XA 2H4KA 1A5YA 1C85A 4Y2EA 3D1HA 3RGOA 3U96A 2F6VA 3BM8A 2YDUA 3EMUA 3RZ2A 3ZM3A 1G4WR 3QCIA 1PTYA 2F6ZA 2QDPA 4GRZA 1J4XA 2HVLA 5IBSA 2HNQA 2CNHA 5BZZA 1Q6PA 5GTJA 5KA9A 4D3QA 2A3KA 2CMCA 4QAHA 2PSZA 3I80A 1U26A 1OETA 2ESBA 5EHPA 1Q6MA 4KYQA 2I4GA 3QCBA 3V0EA 2JJDA 2NZ6A 3D1QA 1GWZA 5KA0A 1U25A 2CJZA 2F70A 2DXPA 3I7ZA 1YTNA 3M4UA 3ZM2A 3MOWA 2QCJA 4GS0A 4AZ1A 1T48A 2Y96A 3V0GA 3GXHA 2R0BA 2OUDA 2E0TA 3F9AA 4OHHA 4KI9A 5K22A 2GJTA 2NTAA 4NWGA 3EB1A 4GFVA 2F6TA 2H4GA 4HRFA 2AZRA 1FPZA 1XBOA 3D9CA 4NX8A 4WTYA 5KA7A 4JMJA 2NV5A 3ZV2A 1LARA 4KYRA 2HNPA 3EZZA 2AHSA 2GWOA 1PXHA 2VEWA 5LXQB 2I3RA 4BPCA 4RHGA 1OEVA 2B4SA 1OEUA 1G1GA 2CNGA 4DGPA 2CMBA 2CFVA 2C7SA 2I6MA 4R30A 4RI4A 5K9VA 4H1OA 4OHEA 4GFUA 2GP0A 3QCEA 3BRHA 2QDMA 5KACA 2HC1A 4QAPA 4IKCA 2G59A 1YGRA 2B4PA 2I3UA 1T4JA 2HCMA 2Q05A 5MMZB 3QCJA 2B3OA 1C86A 3RGQA 5EHRA 3V0FA 5BX1A 4ZI4A 3S3FA 3ZMQA 3D1OA 2Y2FA 4ZRTA 5K24A 2I1YA 1YTSA 4QBEA 2PBNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OEM X;  2M3V A;  2OC3 A;  3MMJ A;  5KA2 A;  3PS5 A;  3BLU A;  3V0J A;  2NT7 A;  1NO6 A;  3S3E A;  1Q6N A;  4PVG A;  3O5X A;  2CNI A;  2HB1 A;  4J51 A;  2C46 A;  2VEV A;  1NWL A;  2I6J A;  3ZM1 A;  4GE2 A;  2HXP A;  4TVV A;  2HC2 A;  1XXP A;  1JF7 A;  1PTV A;  1QXK A;  1P15 A;  1WRM A;  5KA4 A;  4OHI A;  3F81 A;  3I36 A;  3B7O A;  1G7F A;  5KAD A;  3V0D A;  1PA1 A;  2I6P A;  2H02 A;  1FPR A;  1D5R A;  3NME A;  3ZMP A;  1X24 A;  3QCD A;  2OOQ A;  2QBP A;  4WU2 A;  5BZX A;  1ZCK A;  1NNY A;  1EEO A;  3MOZ A;  1OES A;  5K9W A;  2FJM A;  5KA1 A;  1YTW A;  2QDC A;  2F6W A;  3S3H A;  4Z6B A;  4RH9 A;  4D3R A;  3S4O A;  1OHC A;  2I4H A;  2CNF A;  2CM3 A;  1LQF A;  2G6Z A;  2FJN A;  3LJ8 A;  2BZL A;  1I57 A;  2J16 A;  2MBC A;  2A8B A;  4I8N A;  4D3P A;  1YN9 A;  2BGE A;  3QCF A;  3V0H A;  3A5J A;  5K23 A;  5HDE A;  2QBR A;  4ICZ A;  3AWG A;  4DGX A;  5J8R A;  4QUM A;  2VEX A;  4RKK A;  1RXD A;  5BUG A;  1ONZ A;  4MBB A;  1RPM A;  1G4U S;  5KA8 A;  1Q6S A;  2B07 A;  4OHL A;  2Q47 A;  2BV5 A;  1G1F A;  4YR8 B;  1C88 A;  2I4E A;  5M43 A;  3AWE A;  4ZN5 A;  3QCG A;  1KAK A;  1VHR A;  3O4U A;  4BJO A;  5KA3 A;  2CMA A;  1ZC0 A;  3SME A;  2F6Y A;  1FQ1 A;  2I6O A;  4GWF A;  3D44 A;  1Q1M A;  2FH7 A;  1T49 A;  1YZ4 A;  3A5K A;  3SR9 A;  1U24 A;  2SHP A;  3V0I A;  4QBW A;  3QCK A;  3EU0 A;  4RH5 A;  2IMG A;  4JNB A;  5AWX A;  3CWE A;  1LYV A;  2NLK A;  1Q6T A;  1YFO A;  4WU3 A;  1YPT A;  2F6F A;  2P6X A;  3EAX A;  2ZN7 A;  4WOH A;  1ZZW A;  1OHD A;  4JMK A;  3QKQ A;  2BGD A;  5K25 A;  1BZH A;  2H03 A;  2QBS A;  3F41 A;  1JLN A;  1OEO X;  3QCC A;  3QCM A;  3S3K A;  2CM2 A;  3GXG A;  4HJP A;  3OMH A;  4S0G A;  4QUN A;  5KAB A;  3F9B A;  3O3L A;  3O4T A;  1PYN A;  4Y14 A;  4GRY A;  1L8K A;  2I75 A;  4OHD A;  1PH0 A;  2PQ5 A;  5I6V A;  4HJQ A;  1BZJ A;  4ERC A;  3BLT A;  1QZ0 A;  2VEY A;  1EEN A;  1BZC A;  1YGU A;  2F71 A;  3QCH A;  2RF6 A;  2VEU A;  2HY3 A;  1C84 A;  2B49 A;  3ZM0 A;  1C83 A;  2P4D A;  4GE5 A;  1PA9 A;  4RI5 A;  4B04 A;  4NND A;  4R0T A;  4H34 A;  4GE6 A;  2I42 A;  1PTU A;  1OHE A;  5KAA A;  1R6H A;  1XM2 A;  1NWE A;  2I6I A;  4PYH A;  1Q6J A;  1C87 A;  2I5X A;  2B4O A;  1ZCL A;  4NWF A;  2ZMM A;  1AAX A;  3N0A A;  1YWF A;  4RDD A;  1I9S A;  1MKP A;  1XRI A;  3AWF A;  1G1H A;  3QCN A;  3O4S A;  4R0S A;  2B4U A;  3CM3 A;  2PT0 A;  2PI7 A;  1L8G A;  2QBQ A;  3QKP A;  2J17 A;  3D42 A;  3F99 A;  1KAV A;  1GFY A;  2H4V A;  1WCH A;  1XXV A;  1G7G A;  1NZ7 A;  2J16 B;  3OLR A;  1PTT A;  2PA5 A;  2QEP A;  1ECV A;  4YAA A;  1WAX A;  1I9T A;  2QCT A;  2F46 A;  2H04 A;  4NYH A;  2OZ5 A;  2BIJ A;  2CNE A;  4JBC A;  2NT2 A;  3RO1 A;  3S4E A;  5IBM A;  1ONY A;  1SUG A;  1V3A A;  2CM7 A;  1M3G A;  1NL9 A;  3QCL A;  2WGP A;  2CM8 A;  3H2X A;  2H4K A;  1A5Y A;  1C85 A;  4Y2E A;  3D1H A;  3RGO A;  3U96 A;  2F6V A;  3BM8 A;  2YDU A;  3EMU A;  3RZ2 A;  3ZM3 A;  1G4W R;  3QCI A;  1PTY A;  2F6Z A;  2QDP A;  4GRZ A;  1J4X A;  2HVL A;  5IBS A;  2HNQ A;  2CNH A;  5BZZ A;  1Q6P A;  5GTJ A;  5KA9 A;  4D3Q A;  2A3K A;  2CMC A;  4QAH A;  2PSZ A;  3I80 A;  1U26 A;  1OET A;  2ESB A;  5EHP A;  1Q6M A;  4KYQ A;  2I4G A;  3QCB A;  3V0E A;  2JJD A;  2NZ6 A;  3D1Q A;  1GWZ A;  5KA0 A;  1U25 A;  2CJZ A;  2F70 A;  2DXP A;  3I7Z A;  1YTN A;  3M4U A;  3ZM2 A;  3MOW A;  2QCJ A;  4GS0 A;  4AZ1 A;  1T48 A;  2Y96 A;  3V0G A;  3GXH A;  2R0B A;  2OUD A;  2E0T A;  3F9A A;  4OHH A;  4KI9 A;  5K22 A;  2GJT A;  2NTA A;  4NWG A;  3EB1 A;  4GFV A;  2F6T A;  2H4G A;  4HRF A;  2AZR A;  1FPZ A;  1XBO A;  3D9C A;  4NX8 A;  4WTY A;  5KA7 A;  4JMJ A;  2NV5 A;  3ZV2 A;  1LAR A;  4KYR A;  2HNP A;  3EZZ A;  2AHS A;  2GWO A;  1PXH A;  2VEW A;  5LXQ B;  2I3R A;  4BPC A;  4RHG A;  1OEV A;  2B4S A;  1OEU A;  1G1G A;  2CNG A;  4DGP A;  2CMB A;  2CFV A;  2C7S A;  2I6M A;  4R30 A;  4RI4 A;  5K9V A;  4H1O A;  4OHE A;  4GFU A;  2GP0 A;  3QCE A;  3BRH A;  2QDM A;  5KAC A;  2HC1 A;  4QAP A;  4IKC A;  2G59 A;  1YGR A;  2B4P A;  2I3U A;  1T4J A;  2HCM A;  2Q05 A;  5MMZ B;  3QCJ A;  2B3O A;  1C86 A;  3RGQ A;  5EHR A;  3V0F A;  5BX1 A;  4ZI4 A;  3S3F A;  3ZMQ A;  3D1O A;  2Y2F A;  4ZRT A;  5K24 A;  2I1Y A;  1YTS A;  4QBE A;  2PBN A; 
#chains in the Genus database with same CATH topology
 1OEM X;  2M3V A;  2OC3 A;  3MMJ A;  5KA2 A;  3PS5 A;  3BLU A;  3V0J A;  2NT7 A;  1NO6 A;  3S3E A;  1Q6N A;  1J6U A;  4PVG A;  3O5X A;  2CNI A;  2HB1 A;  4J51 A;  2C46 A;  1W7K A;  2VEV A;  1NWL A;  2I6J A;  3ZM1 A;  4GE2 A;  2UAG A;  2HXP A;  4TVV A;  2HC2 A;  1XXP A;  1JF7 A;  2VTD A;  1PTV A;  1QXK A;  1P15 A;  1WRM A;  5KA4 A;  4OHI A;  3F81 A;  5A5F A;  4CVM A;  3I36 A;  3B7O A;  1G7F A;  5KAD A;  3V0D A;  1P3D A;  1PA1 A;  2I6P A;  2H02 A;  1FPR A;  1D5R A;  3NME A;  3ZMP A;  1X24 A;  3QCD A;  2OOQ A;  2QBP A;  4WU2 A;  5BZX A;  1ZCK A;  1E0D A;  1NNY A;  1EEO A;  3MOZ A;  1OES A;  2Y66 A;  5K9W A;  2FJM A;  5KA1 A;  1YTW A;  2QDC A;  2F6W A;  3S3H A;  4Z6B A;  4RH9 A;  4D3R A;  3S4O A;  1OHC A;  2I4H A;  2CNF A;  2CM3 A;  1LQF A;  2G6Z A;  2FJN A;  1GQQ A;  3LJ8 A;  2BZL A;  2VOS A;  1I57 A;  2J16 A;  2MBC A;  2A8B A;  4I8N A;  4D3P A;  1YN9 A;  2BGE A;  3QCF A;  1GG4 A;  3V0H A;  3UAG A;  3A5J A;  5K23 A;  5HDE A;  4BUC A;  2QBR A;  4ICZ A;  3AWG A;  1E8C A;  2XPC A;  4DGX A;  5J8R A;  4QUM A;  2VEX A;  4RKK A;  1RXD A;  5BUG A;  2GCB A;  1ONZ A;  4MBB A;  1RPM A;  1G4U S;  5KA8 A;  1Q6S A;  2B07 A;  3ZL8 A;  4OHL A;  2Q47 A;  1O5Z A;  2BV5 A;  1G1F A;  3QCZ A;  4YR8 B;  1C88 A;  2I4E A;  5M43 A;  3AWE A;  4ZN5 A;  1GQY A;  3QCG A;  1KAK A;  1VHR A;  3O4U A;  4BJO A;  5KA3 A;  2CMA A;  1ZC0 A;  2GCA A;  3SME A;  2F6Y A;  1FQ1 A;  2I6O A;  4GWF A;  3D44 A;  1Q1M A;  2FH7 A;  1T49 A;  1YZ4 A;  3A5K A;  3SR9 A;  4HV4 A;  1U24 A;  2SHP A;  3V0I A;  4QBW A;  3HN7 A;  3PYZ A;  3QCK A;  3EU0 A;  4RH5 A;  2IMG A;  4JNB A;  2VOR A;  1W78 A;  5AWX A;  3CWE A;  1LYV A;  2NLK A;  4QDI A;  1Q6T A;  2VTE A;  1YFO A;  4WU3 A;  1YPT A;  2F6F A;  2P6X A;  3EAX A;  2ZN7 A;  4WOH A;  1ZZW A;  1OHD A;  4JMK A;  4C12 A;  3QKQ A;  2BGD A;  5K25 A;  4BUB A;  1BZH A;  2H03 A;  2QBS A;  3F41 A;  1JLN A;  2Y1O A;  1OEO X;  3QCC A;  3QCM A;  3S3K A;  2CM2 A;  3GXG A;  4HJP A;  3OMH A;  4S0G A;  4QUN A;  5KAB A;  3F9B A;  3O3L A;  3O4T A;  1PYN A;  4Y14 A;  4GRY A;  1L8K A;  2I75 A;  3N2A A;  4OHD A;  1PH0 A;  2PQ5 A;  5I6V A;  4HJQ A;  1BZJ A;  4ERC A;  3BLT A;  1QZ0 A;  2VEY A;  1BZC A;  1EEN A;  1YGU A;  2F71 A;  3QCH A;  2RF6 A;  2VEU A;  2HY3 A;  1C84 A;  2B49 A;  3LK7 A;  3ZM0 A;  1C83 A;  2P4D A;  4GE5 A;  4CVL A;  1PA9 A;  4RI5 A;  4B04 A;  2JFG A;  4NND A;  4R0T A;  4H34 A;  4GE6 A;  2I42 A;  1PTU A;  1OHE A;  5KAA A;  1R6H A;  1XM2 A;  1NWE A;  2I6I A;  2WJP A;  4UAG A;  4PYH A;  1Q6J A;  1C87 A;  2I5X A;  2B4O A;  1ZCL A;  4NWF A;  2ZMM A;  1AAX A;  3N0A A;  5A5E A;  1YWF A;  4RDD A;  1I9S A;  1MKP A;  1XRI A;  3AWF A;  1G1H A;  3QCN A;  3O4S A;  4R0S A;  2B4U A;  3CM3 A;  2PT0 A;  2PI7 A;  1L8G A;  2QBQ A;  3QKP A;  2J17 A;  3D42 A;  3F99 A;  1KAV A;  1GFY A;  2H4V A;  1WCH A;  1XXV A;  1G7G A;  1NZ7 A;  2J16 B;  3OLR A;  1PTT A;  2PA5 A;  2QEP A;  1ECV A;  4YAA A;  4CVK A;  1WAX A;  2XJA A;  1I9T A;  2QCT A;  2F46 A;  2H04 A;  4NYH A;  2OZ5 A;  2BIJ A;  2JFH A;  2CNE A;  2WTZ A;  4JBC A;  2NT2 A;  3RO1 A;  3S4E A;  5IBM A;  2GC6 A;  1ONY A;  3MVN A;  1SUG A;  1V3A A;  2CM7 A;  2Y68 A;  4ZIY A;  1M3G A;  1NL9 A;  3QCL A;  2WGP A;  2CM8 A;  2UUO A;  3H2X A;  2H4K A;  1A5Y A;  1C85 A;  3NRS A;  3D1H A;  4Y2E A;  3RGO A;  3U96 A;  2AM1 A;  2F6V A;  3BM8 A;  1EEH A;  2Y67 A;  2YDU A;  3EMU A;  3RZ2 A;  3ZM3 A;  1G4W R;  3QCI A;  1PTY A;  2F6Z A;  2QDP A;  4GRZ A;  1J4X A;  2HVL A;  5IBS A;  2HNQ A;  2JFF A;  2CNH A;  5BZZ A;  1Q6P A;  2X5O A;  5GTJ A;  5KA9 A;  4D3Q A;  2A3K A;  2CMC A;  2AM2 A;  4QAH A;  4QF5 A;  2PSZ A;  3I80 A;  1U26 A;  1OET A;  2ESB A;  2UUP A;  5EHP A;  1Q6M A;  4KYQ A;  2I4G A;  3QCB A;  3V0E A;  2JJD A;  2NZ6 A;  3D1Q A;  1GWZ A;  4C13 A;  5KA0 A;  1JBW A;  1U25 A;  2CJZ A;  2F70 A;  2DXP A;  3I7Z A;  1YTN A;  3M4U A;  3ZM2 A;  3MOW A;  2QCJ A;  4GS0 A;  4AZ1 A;  1T48 A;  2Y96 A;  1P31 A;  3V0G A;  3GXH A;  2R0B A;  2OUD A;  2E0T A;  3F9A A;  4OHH A;  4KI9 A;  5K22 A;  2GC5 A;  2GJT A;  2NTA A;  4NWG A;  3EB1 A;  4GFV A;  2F00 A;  2F6T A;  2H4G A;  4HRF A;  2AZR A;  1FPZ A;  1XBO A;  3D9C A;  4NX8 A;  4WTY A;  5KA7 A;  4JMJ A;  2NV5 A;  3ZV2 A;  1LAR A;  4KYR A;  2HNP A;  3EZZ A;  2AHS A;  2GWO A;  1PXH A;  2VEW A;  5LXQ B;  2I3R A;  4BPC A;  4RHG A;  1UAG A;  1OEV A;  2B4S A;  1OEU A;  1G1G A;  2CNG A;  4DGP A;  3ZM5 A;  2CMB A;  2CFV A;  2C7S A;  2I6M A;  4R30 A;  4RI4 A;  5K9V A;  4H1O A;  4OHE A;  4GFU A;  2GP0 A;  3QCE A;  3BRH A;  2QDM A;  3ZM6 A;  5KAC A;  2HC1 A;  4QAP A;  4IKC A;  2G59 A;  1YGR A;  2B4P A;  2I3U A;  1T4J A;  2HCM A;  2Q05 A;  5MMZ B;  3QCJ A;  2B3O A;  1C86 A;  3RGQ A;  5EHR A;  3V0F A;  5BX1 A;  1JBV A;  4ZI4 A;  1FGS A;  3S3F A;  3ZMQ A;  3D1O A;  2Y2F A;  4ZRT A;  5K24 A;  2I1Y A;  1YTS A;  4QBE A;  2PBN A; 
#chains in the Genus database with same CATH homology
 1OEM X;  2M3V A;  2OC3 A;  3MMJ A;  5KA2 A;  3PS5 A;  3BLU A;  3V0J A;  2NT7 A;  1NO6 A;  3S3E A;  1Q6N A;  4PVG A;  3O5X A;  2CNI A;  2HB1 A;  4J51 A;  2C46 A;  2VEV A;  1NWL A;  2I6J A;  3ZM1 A;  4GE2 A;  2HXP A;  4TVV A;  2HC2 A;  1XXP A;  1JF7 A;  1PTV A;  1QXK A;  1P15 A;  1WRM A;  5KA4 A;  4OHI A;  3F81 A;  3I36 A;  3B7O A;  1G7F A;  5KAD A;  3V0D A;  1PA1 A;  2I6P A;  2H02 A;  1FPR A;  1D5R A;  3NME A;  3ZMP A;  1X24 A;  3QCD A;  2OOQ A;  2QBP A;  4WU2 A;  5BZX A;  1ZCK A;  1NNY A;  1EEO A;  3MOZ A;  1OES A;  5K9W A;  2FJM A;  5KA1 A;  1YTW A;  2QDC A;  2F6W A;  3S3H A;  4Z6B A;  4RH9 A;  4D3R A;  3S4O A;  1OHC A;  2I4H A;  2CNF A;  2CM3 A;  1LQF A;  2G6Z A;  2FJN A;  3LJ8 A;  2BZL A;  1I57 A;  2J16 A;  2MBC A;  2A8B A;  4I8N A;  4D3P A;  1YN9 A;  2BGE A;  3QCF A;  3V0H A;  3A5J A;  5K23 A;  5HDE A;  2QBR A;  4ICZ A;  3AWG A;  4DGX A;  5J8R A;  4QUM A;  2VEX A;  4RKK A;  1RXD A;  5BUG A;  1ONZ A;  4MBB A;  1RPM A;  1G4U S;  5KA8 A;  1Q6S A;  2B07 A;  4OHL A;  2Q47 A;  2BV5 A;  1G1F A;  4YR8 B;  1C88 A;  2I4E A;  5M43 A;  3AWE A;  4ZN5 A;  3QCG A;  1KAK A;  1VHR A;  3O4U A;  4BJO A;  5KA3 A;  2CMA A;  1ZC0 A;  3SME A;  2F6Y A;  1FQ1 A;  2I6O A;  4GWF A;  3D44 A;  1Q1M A;  2FH7 A;  1T49 A;  1YZ4 A;  3A5K A;  3SR9 A;  1U24 A;  2SHP A;  3V0I A;  4QBW A;  3QCK A;  3EU0 A;  4RH5 A;  2IMG A;  4JNB A;  5AWX A;  3CWE A;  1LYV A;  2NLK A;  1Q6T A;  1YFO A;  4WU3 A;  1YPT A;  2F6F A;  2P6X A;  3EAX A;  2ZN7 A;  4WOH A;  1ZZW A;  1OHD A;  4JMK A;  3QKQ A;  2BGD A;  5K25 A;  1BZH A;  2H03 A;  2QBS A;  3F41 A;  1JLN A;  1OEO X;  3QCC A;  3QCM A;  3S3K A;  2CM2 A;  3GXG A;  4HJP A;  3OMH A;  4S0G A;  4QUN A;  5KAB A;  3F9B A;  3O3L A;  3O4T A;  1PYN A;  4Y14 A;  4GRY A;  1L8K A;  2I75 A;  4OHD A;  1PH0 A;  2PQ5 A;  5I6V A;  4HJQ A;  1BZJ A;  4ERC A;  3BLT A;  1QZ0 A;  2VEY A;  1EEN A;  1BZC A;  1YGU A;  2F71 A;  3QCH A;  2RF6 A;  2VEU A;  2HY3 A;  1C84 A;  2B49 A;  3ZM0 A;  1C83 A;  2P4D A;  4GE5 A;  1PA9 A;  4RI5 A;  4B04 A;  4NND A;  4R0T A;  4H34 A;  4GE6 A;  2I42 A;  1PTU A;  1OHE A;  5KAA A;  1R6H A;  1XM2 A;  1NWE A;  2I6I A;  4PYH A;  1Q6J A;  1C87 A;  2I5X A;  2B4O A;  1ZCL A;  4NWF A;  2ZMM A;  1AAX A;  3N0A A;  1YWF A;  4RDD A;  1I9S A;  1MKP A;  1XRI A;  3AWF A;  1G1H A;  3QCN A;  3O4S A;  4R0S A;  2B4U A;  3CM3 A;  2PT0 A;  2PI7 A;  1L8G A;  2QBQ A;  3QKP A;  2J17 A;  3D42 A;  3F99 A;  1KAV A;  1GFY A;  2H4V A;  1WCH A;  1XXV A;  1G7G A;  1NZ7 A;  2J16 B;  3OLR A;  1PTT A;  2PA5 A;  2QEP A;  1ECV A;  4YAA A;  1WAX A;  1I9T A;  2QCT A;  2F46 A;  2H04 A;  4NYH A;  2OZ5 A;  2BIJ A;  2CNE A;  4JBC A;  2NT2 A;  3RO1 A;  3S4E A;  5IBM A;  1ONY A;  1SUG A;  1V3A A;  2CM7 A;  1M3G A;  1NL9 A;  3QCL A;  2WGP A;  2CM8 A;  3H2X A;  2H4K A;  1A5Y A;  1C85 A;  4Y2E A;  3D1H A;  3RGO A;  3U96 A;  2F6V A;  3BM8 A;  2YDU A;  3EMU A;  3RZ2 A;  3ZM3 A;  1G4W R;  3QCI A;  1PTY A;  2F6Z A;  2QDP A;  4GRZ A;  1J4X A;  2HVL A;  5IBS A;  2HNQ A;  2CNH A;  5BZZ A;  1Q6P A;  5GTJ A;  5KA9 A;  4D3Q A;  2A3K A;  2CMC A;  4QAH A;  2PSZ A;  3I80 A;  1U26 A;  1OET A;  2ESB A;  5EHP A;  1Q6M A;  4KYQ A;  2I4G A;  3QCB A;  3V0E A;  2JJD A;  2NZ6 A;  3D1Q A;  1GWZ A;  5KA0 A;  1U25 A;  2CJZ A;  2F70 A;  2DXP A;  3I7Z A;  1YTN A;  3M4U A;  3ZM2 A;  3MOW A;  2QCJ A;  4GS0 A;  4AZ1 A;  1T48 A;  2Y96 A;  3V0G A;  3GXH A;  2R0B A;  2OUD A;  2E0T A;  3F9A A;  4OHH A;  4KI9 A;  5K22 A;  2GJT A;  2NTA A;  4NWG A;  3EB1 A;  4GFV A;  2F6T A;  2H4G A;  4HRF A;  2AZR A;  1FPZ A;  1XBO A;  3D9C A;  4NX8 A;  4WTY A;  5KA7 A;  4JMJ A;  2NV5 A;  3ZV2 A;  1LAR A;  4KYR A;  2HNP A;  3EZZ A;  2AHS A;  2GWO A;  1PXH A;  2VEW A;  5LXQ B;  2I3R A;  4BPC A;  4RHG A;  1OEV A;  2B4S A;  1OEU A;  1G1G A;  2CNG A;  4DGP A;  2CMB A;  2CFV A;  2C7S A;  2I6M A;  4R30 A;  4RI4 A;  5K9V A;  4H1O A;  4OHE A;  4GFU A;  2GP0 A;  3QCE A;  3BRH A;  2QDM A;  5KAC A;  2HC1 A;  4QAP A;  4IKC A;  2G59 A;  1YGR A;  2B4P A;  2I3U A;  1T4J A;  2HCM A;  2Q05 A;  5MMZ B;  3QCJ A;  2B3O A;  1C86 A;  3RGQ A;  5EHR A;  3V0F A;  5BX1 A;  4ZI4 A;  3S3F A;  3ZMQ A;  3D1O A;  2Y2F A;  4ZRT A;  5K24 A;  2I1Y A;  1YTS A;  4QBE A;  2PBN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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