5KA8A

Protein tyrosine phosphatase 1b l192a mutant, open state
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
289
structure length
289
Chain Sequence
GHMASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFANFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 105
structure length 289
sequence length 289
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka8A00
2B49A 1ZC0A 4GE5A 3MMJA 4WOHA 4QAHA 2CM2A 2QCJA 1PTTA 2NZ6A 2I6MA 2B4OA 2BV5A 1C87A 2F6WA 2HC2A 1D5RA 5LXQB 1YN9A 4WTYA 5KA4A 1R6HA 4ZI4A 3ZM2A 2I42A 2AZRA 3D42A 1Q6NA 2CNGA 3QCCA 4RH5A 2HC1A 1G1HA 5MMZB 2Y2FA 2QCTA 5KADA 2QBPA 1U24A 2P4DA 1G7GA 3D9CA 4DGPA 1YFOA 1YTNA 4MBBA 3O5XA 3NMEA 2GP0A 1NWLA 5I6VA 1OEOX 4PYHA 1LYVA 5BZXA 3S3FA 4QAPA 3RGQA 3QKPA 4ZRTA 2HB1A 4H1OA 4D3PA 1T49A 1A5YA 1OEMX 1YTSA 1KAVA 3I80A 5GTJA 2HCMA 2H4VA 2CNEA 4GRZA 4OHIA 2I4EA 1G1GA 1VHRA 1OHCA 1ZZWA 1G4US 4QBEA 4GS0A 4NNDA 4NX8A 2I6IA 2F6ZA 3CWEA 5EHRA 3QCFA 1XXPA 5EHPA 4JMKA 4OHHA 2CM8A 2CMAA 1JF7A 1PA1A 1C84A 1SUGA 1YWFA 4PVGA 2H03A 1OEVA 2AHSA 2PBNA 4GWFA 1NO6A 1G4WR 2H02A 2A3KA 2I3RA 1BZJA 2G6ZA 1OHDA 2QDCA 1WAXA 2G59A 2PSZA 1YGRA 2F6TA 3D1OA 1T4JA 2ZN7A 3I7ZA 1YTWA 4QUMA 1PH0A 4GFUA 5K9VA 1C86A 1PXHA 2PI7A 1OETA 4BJOA 5BX1A 2I5XA 1Q6TA 1T48A 4BPCA 2I6JA 3ZM1A 1FPZA 1Q6PA 1PTUA 1RXDA 1ECVA 4Y2EA 2I6OA 5KA8A 4JBCA 3O4UA 4GRYA 2QEPA 5KA9A 2VEWA 1FQ1A 2OUDA 1ONZA 1V3AA 3H2XA 2NLKA 3ZMQA 3ZM0A 3EMUA 2C46A 1YPTA 2PA5A 1Q6SA 2CM7A 2M3VA 3B7OA 5K25A 2FJMA 3V0FA 1JLNA 2FJNA 4D3QA 3QCDA 3S3EA 5KABA 5KACA 1NL9A 3EU0A 4HJPA 4R0SA 1M3GA 3EZZA 1C88A 2CJZA 1QXKA 1XM2A 2F46A 1XRIA 2PT0A 2DXPA 2HVLA 4B04A 2VEYA 1LARA 5HDEA 5K23A 5M43A 4DGXA 3O4TA 2BIJA 2F70A 1FPRA 3N0AA 1G1FA 5KA0A 2R0BA 2QBQA 1WCHA 1YZ4A 3I36A 2Q47A 3BLUA 3F41A 2NT2A 2H4GA 2NTAA 2QDPA 4JMJA 4OHLA 4KI9A 3QCHA 3EB1A 3A5KA 4NYHA 4WU3A 1I9SA 1Q1MA 3S4OA 2ESBA 4GFVA 5K22A 3QCJA 2CFVA 1L8GA 4HJQA 4HRFA 4RDDA 3QCIA 1U26A 1J4XA 5J8RA 5KA1A 5K9WA 4ICZA 2VEUA 2I75A 4RKKA 1GFYA 4OHEA 4J51A 5KA7A 2F71A 3V0HA 4H34A 1OEUA 1GWZA 2HNPA 4JNBA 3GXHA 4TVVA 3SMEA 2F6VA 3A5JA 1C83A 3OMHA 2JJDA 4R0TA 3QCEA 1Q6JA 2QBRA 3BLTA 3O4SA 4YAAA 4AZ1A 3M4UA 3QCNA 1XXVA 3F9AA 1BZCA 2MBCA 3ZV2A 3D1HA 1P15A 3S3HA 2FH7A 3RGOA 2PQ5A 2HXPA 2B07A 1BZHA 2J16A 4OHDA 4RI5A 3PS5A 4WU2A 1PTYA 3RO1A 3V0JA 4S0GA 3ZM3A 5IBSA 2I4HA 2QBSA 1WRMA 2BGEA 2B4UA 3D44A 5K24A 4ZN5A 3U96A 1NNYA 4KYRA 2GJTA 2I4GA 3GXGA 2B3OA 1C85A 1X24A 3BM8A 4KYQA 2CMBA 3OLRA 3QCLA 4Y14A 1YGUA 3QCMA 3AWEA 3S4EA 2F6YA 3QCKA 2OC3A 2SHPA 4I8NA 2Q05A 4YR8B 4IKCA 2VEXA 3MOZA 1U25A 2P6XA 1ZCKA 1OHEA 2IMGA 2F6FA 1KAKA 1OESA 2J17A 3O3LA 1EEOA 1PYNA 4RI4A 5BZZA 2J16B 2QDMA 1AAXA 4GE2A 2H04A 1L8KA 3MOWA 2OOQA 4GE6A 5KAAA 1QZ0A 4NWFA 1I9TA 4R30A 2CMCA 3V0GA 3ZMPA 2WGPA 1XBOA 2HNQA 3EAXA 5KA3A 4Z6BA 3AWFA 1MKPA 2I1YA 2C7SA 1I57A 2OZ5A 2B4PA 3F99A 3BRHA 5BUGA 2B4SA 2NV5A 4RH9A 3F9BA 3SR9A 1EENA 1LQFA 1NZ7A 3CM3A 1NWEA 1ONYA 2A8BA 2BZLA 2Y96A 3QCBA 5AWXA 4D3RA 3AWGA 3V0IA 1G7FA 2YDUA 3RZ2A 1Q6MA 5IBMA 2BGDA 2HY3A 4QBWA 4ERCA 2CNHA 2H4KA 2GWOA 3QKQA 2RF6A 2CNFA 3S3KA 4RHGA 1ZCLA 3V0DA 2I3UA 2I6PA 3D1QA 5KA2A 1PTVA 2CM3A 2VEVA 2ZMMA 3F81A 3V0EA 1PA9A 4NWGA 2CNIA 4QUNA 2NT7A 1RPMA 2E0TA 3LJ8A 3QCGA
chains in the Genus database with same CATH superfamily
2B49A 1ZC0A 4GE5A 3MMJA 4WOHA 4QAHA 3MVNA 2CM2A 2QCJA 1PTTA 2NZ6A 4QDIA 2I6MA 2B4OA 4BUCA 2BV5A 1C87A 2F6WA 2HC2A 2GC6A 4QF5A 1D5RA 5LXQB 1YN9A 4WTYA 5KA4A 1R6HA 4ZI4A 3ZM2A 1FGSA 2I42A 2AZRA 3D42A 1Q6NA 2CNGA 3QCCA 4RH5A 2HC1A 1G1HA 5MMZB 2Y2FA 2QCTA 5KADA 1E0DA 2QBPA 1U24A 2P4DA 1G7GA 3D9CA 4DGPA 2GCBA 1YFOA 1YTNA 3ZM6A 4MBBA 3O5XA 3NMEA 2GP0A 1NWLA 3ZL8A 5I6VA 1OEOX 4PYHA 1LYVA 5BZXA 3S3FA 4QAPA 3RGQA 3QKPA 2VTEA 4ZRTA 2HB1A 4H1OA 4D3PA 1T49A 1A5YA 1OEMX 1YTSA 1KAVA 3I80A 5GTJA 2HCMA 1P3DA 2H4VA 2CNEA 4GRZA 4OHIA 2I4EA 1G1GA 1VHRA 1OHCA 1ZZWA 1G4US 4QBEA 4GS0A 1J6UA 4NNDA 4NX8A 1E8CA 2I6IA 2F6ZA 5A5EA 3CWEA 2UUPA 5EHRA 3QCFA 1XXPA 2XPCA 5EHPA 4JMKA 4OHHA 1W7KA 2CM8A 2CMAA 1JF7A 1PA1A 1C84A 1SUGA 1YWFA 4PVGA 2H03A 1OEVA 2AHSA 2PBNA 4GWFA 1NO6A 1G4WR 2H02A 2A3KA 2I3RA 1BZJA 2G6ZA 1OHDA 2QDCA 1WAXA 2WTZA 2G59A 2PSZA 1YGRA 2F6TA 1O5ZA 3D1OA 3N2AA 5A5FA 1T4JA 2ZN7A 3I7ZA 1YTWA 4QUMA 1PH0A 4GFUA 5K9VA 1C86A 1PXHA 2PI7A 1OETA 2Y67A 4BJOA 5BX1A 1JBWA 2I5XA 1Q6TA 2AM2A 1T48A 2Y1OA 4BPCA 2I6JA 3ZM1A 1FPZA 1Q6PA 1PTUA 1RXDA 1ECVA 2GC5A 4Y2EA 2I6OA 5KA8A 4JBCA 3O4UA 4GRYA 2QEPA 5KA9A 2VEWA 1FQ1A 2OUDA 2VORA 1ONZA 1V3AA 3H2XA 2NLKA 3ZMQA 3ZM0A 1UAGA 3EMUA 2C46A 1YPTA 2PA5A 1Q6SA 2CM7A 3QCZA 2M3VA 3B7OA 5K25A 2FJMA 3V0FA 1JLNA 3HN7A 2FJNA 4D3QA 3QCDA 3S3EA 1GG4A 5KABA 5KACA 1NL9A 3EU0A 4HJPA 4R0SA 1M3GA 3EZZA 1GQYA 1C88A 2CJZA 1QXKA 1XM2A 2F46A 1XRIA 2PT0A 2DXPA 2HVLA 4B04A 2VEYA 1LARA 5HDEA 5K23A 5M43A 4DGXA 3O4TA 2BIJA 2F70A 2AM1A 1FPRA 3N0AA 1G1FA 5KA0A 2R0BA 2QBQA 1WCHA 1YZ4A 3I36A 3BLUA 2Q47A 3F41A 2NT2A 2H4GA 2NTAA 2QDPA 4JMJA 4OHLA 4KI9A 3QCHA 3EB1A 3A5KA 4NYHA 4WU3A 1I9SA 1Q1MA 2XJAA 3S4OA 2ESBA 4GFVA 5K22A 3QCJA 2CFVA 1L8GA 4HJQA 4HRFA 4RDDA 3QCIA 1U26A 1J4XA 5J8RA 5KA1A 5K9WA 4ICZA 2VEUA 2I75A 4RKKA 1GFYA 4OHEA 4J51A 5KA7A 2F71A 3V0HA 4H34A 1OEUA 1GWZA 2HNPA 4JNBA 3GXHA 4TVVA 3SMEA 2F6VA 4ZIYA 3A5JA 1C83A 3OMHA 2JJDA 4R0TA 4UAGA 3QCEA 1Q6JA 3PYZA 2QBRA 3BLTA 3O4SA 1GQQA 4YAAA 4AZ1A 3M4UA 3QCNA 1XXVA 3F9AA 1BZCA 2MBCA 3ZV2A 3D1HA 1P15A 3S3HA 2FH7A 3RGOA 2PQ5A 2JFGA 2HXPA 2B07A 1BZHA 2J16A 4OHDA 4RI5A 3PS5A 4WU2A 2Y66A 1PTYA 3RO1A 3V0JA 1W78A 4S0GA 3ZM3A 5IBSA 2WJPA 2I4HA 2QBSA 1WRMA 2BGEA 2B4UA 3D44A 5K24A 4ZN5A 3U96A 1NNYA 4KYRA 2GJTA 2I4GA 3GXGA 2B3OA 1C85A 1X24A 3BM8A 4KYQA 2CMBA 3OLRA 3QCLA 4Y14A 1YGUA 3QCMA 3AWEA 3S4EA 2F6YA 2OC3A 3QCKA 2SHPA 4I8NA 2Q05A 4YR8B 4IKCA 2VEXA 3ZM5A 3MOZA 1U25A 2P6XA 1ZCKA 1OHEA 2IMGA 3LK7A 2F6FA 1KAKA 1OESA 2J17A 3O3LA 4C13A 1EEOA 1PYNA 4RI4A 4C12A 5BZZA 2J16B 4CVLA 2JFFA 2QDMA 1AAXA 4GE2A 2H04A 1L8KA 3MOWA 2OOQA 4GE6A 5KAAA 1QZ0A 4NWFA 1I9TA 4R30A 2CMCA 3V0GA 3ZMPA 2WGPA 1XBOA 2HNQA 3EAXA 5KA3A 4Z6BA 1JBVA 2Y68A 3AWFA 4CVKA 1MKPA 2I1YA 2C7SA 1I57A 2OZ5A 3UAGA 4BUBA 2B4PA 3F99A 3BRHA 5BUGA 2B4SA 2NV5A 4RH9A 3F9BA 3SR9A 1EENA 1LQFA 1NZ7A 3CM3A 2VTDA 1NWEA 1ONYA 2A8BA 2BZLA 2Y96A 3QCBA 5AWXA 4D3RA 3AWGA 4CVMA 3V0IA 1G7FA 2YDUA 4HV4A 3RZ2A 1Q6MA 1EEHA 2X5OA 5IBMA 2BGDA 2HY3A 4QBWA 4ERCA 2UAGA 2VOSA 2JFHA 2CNHA 2GCAA 2H4KA 2GWOA 3QKQA 2RF6A 2CNFA 3S3KA 4RHGA 1ZCLA 3V0DA 2I3UA 2I6PA 3D1QA 2F00A 5KA2A 1PTVA 2CM3A 2VEVA 2ZMMA 3F81A 3V0EA 1PA9A 3NRSA 1P31A 4NWGA 2CNIA 4QUNA 2NT7A 1RPMA 2E0TA 2UUOA 3LJ8A 3QCGA
chains in the Genus database with same CATH topology
2B49A 1ZC0A 4GE5A 3MMJA 4WOHA 4QAHA 2CM2A 2QCJA 1PTTA 2NZ6A 2I6MA 2B4OA 2BV5A 1C87A 2F6WA 2HC2A 1D5RA 5LXQB 1YN9A 4WTYA 5KA4A 1R6HA 4ZI4A 3ZM2A 2I42A 2AZRA 3D42A 1Q6NA 2CNGA 3QCCA 4RH5A 2HC1A 1G1HA 5MMZB 2Y2FA 2QCTA 5KADA 2QBPA 1U24A 2P4DA 1G7GA 3D9CA 4DGPA 1YFOA 1YTNA 4MBBA 3O5XA 3NMEA 2GP0A 1NWLA 5I6VA 1OEOX 4PYHA 1LYVA 5BZXA 3S3FA 4QAPA 3RGQA 3QKPA 4ZRTA 2HB1A 4H1OA 4D3PA 1T49A 1A5YA 1OEMX 1YTSA 1KAVA 3I80A 5GTJA 2HCMA 2H4VA 2CNEA 4GRZA 4OHIA 2I4EA 1G1GA 1VHRA 1OHCA 1ZZWA 1G4US 4QBEA 4GS0A 4NNDA 4NX8A 2I6IA 2F6ZA 3CWEA 5EHRA 3QCFA 1XXPA 5EHPA 4JMKA 4OHHA 2CM8A 2CMAA 1JF7A 1PA1A 1C84A 1SUGA 1YWFA 4PVGA 2H03A 1OEVA 2AHSA 2PBNA 4GWFA 1NO6A 1G4WR 2H02A 2A3KA 2I3RA 1BZJA 2G6ZA 1OHDA 2QDCA 1WAXA 2G59A 2PSZA 1YGRA 2F6TA 3D1OA 1T4JA 2ZN7A 3I7ZA 1YTWA 4QUMA 1PH0A 4GFUA 5K9VA 1C86A 1PXHA 2PI7A 1OETA 4BJOA 5BX1A 2I5XA 1Q6TA 1T48A 4BPCA 2I6JA 3ZM1A 1FPZA 1Q6PA 1PTUA 1RXDA 1ECVA 4Y2EA 2I6OA 5KA8A 4JBCA 3O4UA 4GRYA 2QEPA 5KA9A 2VEWA 1FQ1A 2OUDA 1ONZA 1V3AA 3H2XA 2NLKA 3ZMQA 3ZM0A 3EMUA 2C46A 1YPTA 2PA5A 1Q6SA 2CM7A 2M3VA 3B7OA 5K25A 2FJMA 3V0FA 1JLNA 2FJNA 4D3QA 3QCDA 3S3EA 5KABA 5KACA 1NL9A 3EU0A 4HJPA 4R0SA 1M3GA 3EZZA 1C88A 2CJZA 1QXKA 1XM2A 2F46A 1XRIA 2PT0A 2DXPA 2HVLA 4B04A 2VEYA 1LARA 5HDEA 5K23A 5M43A 4DGXA 3O4TA 2BIJA 2F70A 1FPRA 3N0AA 1G1FA 5KA0A 2R0BA 2QBQA 1WCHA 1YZ4A 3I36A 2Q47A 3BLUA 3F41A 2NT2A 2H4GA 2NTAA 2QDPA 4JMJA 4OHLA 4KI9A 3QCHA 3EB1A 3A5KA 4NYHA 4WU3A 1I9SA 1Q1MA 3S4OA 2ESBA 4GFVA 5K22A 3QCJA 2CFVA 1L8GA 4HJQA 4HRFA 4RDDA 3QCIA 1U26A 1J4XA 5J8RA 5KA1A 5K9WA 4ICZA 2VEUA 2I75A 4RKKA 1GFYA 4OHEA 4J51A 5KA7A 2F71A 3V0HA 4H34A 1OEUA 1GWZA 2HNPA 4JNBA 3GXHA 4TVVA 3SMEA 2F6VA 3A5JA 1C83A 3OMHA 2JJDA 4R0TA 3QCEA 1Q6JA 2QBRA 3BLTA 3O4SA 4YAAA 4AZ1A 3M4UA 3QCNA 1XXVA 3F9AA 1BZCA 2MBCA 3ZV2A 3D1HA 1P15A 3S3HA 2FH7A 3RGOA 2PQ5A 2HXPA 2B07A 1BZHA 2J16A 4OHDA 4RI5A 3PS5A 4WU2A 1PTYA 3RO1A 3V0JA 4S0GA 3ZM3A 5IBSA 2I4HA 2QBSA 1WRMA 2BGEA 2B4UA 3D44A 5K24A 4ZN5A 3U96A 1NNYA 4KYRA 2GJTA 2I4GA 3GXGA 2B3OA 1C85A 1X24A 3BM8A 4KYQA 2CMBA 3OLRA 3QCLA 4Y14A 1YGUA 3QCMA 3AWEA 3S4EA 2F6YA 3QCKA 2OC3A 2SHPA 4I8NA 2Q05A 4YR8B 4IKCA 2VEXA 3MOZA 1U25A 2P6XA 1ZCKA 1OHEA 2IMGA 2F6FA 1KAKA 1OESA 2J17A 3O3LA 1EEOA 1PYNA 4RI4A 5BZZA 2J16B 2QDMA 1AAXA 4GE2A 2H04A 1L8KA 3MOWA 2OOQA 4GE6A 5KAAA 1QZ0A 4NWFA 1I9TA 4R30A 2CMCA 3V0GA 3ZMPA 2WGPA 1XBOA 2HNQA 3EAXA 5KA3A 4Z6BA 3AWFA 1MKPA 2I1YA 2C7SA 1I57A 2OZ5A 2B4PA 3F99A 3BRHA 5BUGA 2B4SA 2NV5A 4RH9A 3F9BA 3SR9A 1EENA 1LQFA 1NZ7A 3CM3A 1NWEA 1ONYA 2A8BA 2BZLA 2Y96A 3QCBA 5AWXA 4D3RA 3AWGA 3V0IA 1G7FA 2YDUA 3RZ2A 1Q6MA 5IBMA 2BGDA 2HY3A 4QBWA 4ERCA 2CNHA 2H4KA 2GWOA 3QKQA 2RF6A 2CNFA 3S3KA 4RHGA 1ZCLA 3V0DA 2I3UA 2I6PA 3D1QA 5KA2A 1PTVA 2CM3A 2VEVA 2ZMMA 3F81A 3V0EA 1PA9A 4NWGA 2CNIA 4QUNA 2NT7A 1RPMA 2E0TA 3LJ8A 3QCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B49 A;  1ZC0 A;  4GE5 A;  3MMJ A;  4WOH A;  4QAH A;  2CM2 A;  2QCJ A;  1PTT A;  2NZ6 A;  2I6M A;  2B4O A;  2BV5 A;  1C87 A;  2F6W A;  2HC2 A;  1D5R A;  5LXQ B;  1YN9 A;  4WTY A;  5KA4 A;  1R6H A;  4ZI4 A;  3ZM2 A;  2I42 A;  2AZR A;  3D42 A;  1Q6N A;  2CNG A;  3QCC A;  4RH5 A;  2HC1 A;  1G1H A;  5MMZ B;  2Y2F A;  2QCT A;  5KAD A;  2QBP A;  1U24 A;  2P4D A;  1G7G A;  3D9C A;  4DGP A;  1YFO A;  1YTN A;  4MBB A;  3O5X A;  3NME A;  2GP0 A;  1NWL A;  5I6V A;  1OEO X;  4PYH A;  1LYV A;  5BZX A;  3S3F A;  4QAP A;  3RGQ A;  3QKP A;  4ZRT A;  2HB1 A;  4H1O A;  4D3P A;  1T49 A;  1A5Y A;  1OEM X;  1YTS A;  1KAV A;  3I80 A;  5GTJ A;  2HCM A;  2H4V A;  2CNE A;  4GRZ A;  4OHI A;  2I4E A;  1G1G A;  1VHR A;  1OHC A;  1ZZW A;  1G4U S;  4QBE A;  4GS0 A;  4NND A;  4NX8 A;  2I6I A;  2F6Z A;  3CWE A;  5EHR A;  3QCF A;  1XXP A;  5EHP A;  4JMK A;  4OHH A;  2CM8 A;  2CMA A;  1JF7 A;  1PA1 A;  1C84 A;  1SUG A;  1YWF A;  4PVG A;  2H03 A;  1OEV A;  2AHS A;  2PBN A;  4GWF A;  1NO6 A;  1G4W R;  2H02 A;  2A3K A;  2I3R A;  1BZJ A;  2G6Z A;  1OHD A;  2QDC A;  1WAX A;  2G59 A;  2PSZ A;  1YGR A;  2F6T A;  3D1O A;  1T4J A;  2ZN7 A;  3I7Z A;  1YTW A;  4QUM A;  1PH0 A;  4GFU A;  5K9V A;  1C86 A;  1PXH A;  2PI7 A;  1OET A;  4BJO A;  5BX1 A;  2I5X A;  1Q6T A;  1T48 A;  4BPC A;  2I6J A;  3ZM1 A;  1FPZ A;  1Q6P A;  1PTU A;  1RXD A;  1ECV A;  4Y2E A;  2I6O A;  5KA8 A;  4JBC A;  3O4U A;  4GRY A;  2QEP A;  5KA9 A;  2VEW A;  1FQ1 A;  2OUD A;  1ONZ A;  1V3A A;  3H2X A;  2NLK A;  3ZMQ A;  3ZM0 A;  3EMU A;  2C46 A;  1YPT A;  2PA5 A;  1Q6S A;  2CM7 A;  2M3V A;  3B7O A;  5K25 A;  2FJM A;  3V0F A;  1JLN A;  2FJN A;  4D3Q A;  3QCD A;  3S3E A;  5KAB A;  5KAC A;  1NL9 A;  3EU0 A;  4HJP A;  4R0S A;  1M3G A;  3EZZ A;  1C88 A;  2CJZ A;  1QXK A;  1XM2 A;  2F46 A;  1XRI A;  2PT0 A;  2DXP A;  2HVL A;  4B04 A;  2VEY A;  1LAR A;  5HDE A;  5K23 A;  5M43 A;  4DGX A;  3O4T A;  2BIJ A;  2F70 A;  1FPR A;  3N0A A;  1G1F A;  5KA0 A;  2R0B A;  2QBQ A;  1WCH A;  1YZ4 A;  3I36 A;  2Q47 A;  3BLU A;  3F41 A;  2NT2 A;  2H4G A;  2NTA A;  2QDP A;  4JMJ A;  4OHL A;  4KI9 A;  3QCH A;  3EB1 A;  3A5K A;  4NYH A;  4WU3 A;  1I9S A;  1Q1M A;  3S4O A;  2ESB A;  4GFV A;  5K22 A;  3QCJ A;  2CFV A;  1L8G A;  4HJQ A;  4HRF A;  4RDD A;  3QCI A;  1U26 A;  1J4X A;  5J8R A;  5KA1 A;  5K9W A;  4ICZ A;  2VEU A;  2I75 A;  4RKK A;  1GFY A;  4OHE A;  4J51 A;  5KA7 A;  2F71 A;  3V0H A;  4H34 A;  1OEU A;  1GWZ A;  2HNP A;  4JNB A;  3GXH A;  4TVV A;  3SME A;  2F6V A;  3A5J A;  1C83 A;  3OMH A;  2JJD A;  4R0T A;  3QCE A;  1Q6J A;  2QBR A;  3BLT A;  3O4S A;  4YAA A;  4AZ1 A;  3M4U A;  3QCN A;  1XXV A;  3F9A A;  1BZC A;  2MBC A;  3ZV2 A;  3D1H A;  1P15 A;  3S3H A;  2FH7 A;  3RGO A;  2PQ5 A;  2HXP A;  2B07 A;  1BZH A;  2J16 A;  4OHD A;  4RI5 A;  3PS5 A;  4WU2 A;  1PTY A;  3RO1 A;  3V0J A;  4S0G A;  3ZM3 A;  5IBS A;  2I4H A;  2QBS A;  1WRM A;  2BGE A;  2B4U A;  3D44 A;  5K24 A;  4ZN5 A;  3U96 A;  1NNY A;  4KYR A;  2GJT A;  2I4G A;  3GXG A;  2B3O A;  1C85 A;  1X24 A;  3BM8 A;  4KYQ A;  2CMB A;  3OLR A;  3QCL A;  4Y14 A;  1YGU A;  3QCM A;  3AWE A;  3S4E A;  2F6Y A;  3QCK A;  2OC3 A;  2SHP A;  4I8N A;  2Q05 A;  4YR8 B;  4IKC A;  2VEX A;  3MOZ A;  1U25 A;  2P6X A;  1ZCK A;  1OHE A;  2IMG A;  2F6F A;  1KAK A;  1OES A;  2J17 A;  3O3L A;  1EEO A;  1PYN A;  4RI4 A;  5BZZ A;  2J16 B;  2QDM A;  1AAX A;  4GE2 A;  2H04 A;  1L8K A;  3MOW A;  2OOQ A;  4GE6 A;  5KAA A;  1QZ0 A;  4NWF A;  1I9T A;  4R30 A;  2CMC A;  3V0G A;  3ZMP A;  2WGP A;  1XBO A;  2HNQ A;  3EAX A;  5KA3 A;  4Z6B A;  3AWF A;  1MKP A;  2I1Y A;  2C7S A;  1I57 A;  2OZ5 A;  2B4P A;  3F99 A;  3BRH A;  5BUG A;  2B4S A;  2NV5 A;  4RH9 A;  3F9B A;  3SR9 A;  1EEN A;  1LQF A;  1NZ7 A;  3CM3 A;  1NWE A;  1ONY A;  2A8B A;  2BZL A;  2Y96 A;  3QCB A;  5AWX A;  4D3R A;  3AWG A;  3V0I A;  1G7F A;  2YDU A;  3RZ2 A;  1Q6M A;  5IBM A;  2BGD A;  2HY3 A;  4QBW A;  4ERC A;  2CNH A;  2H4K A;  2GWO A;  3QKQ A;  2RF6 A;  2CNF A;  3S3K A;  4RHG A;  1ZCL A;  3V0D A;  2I3U A;  2I6P A;  3D1Q A;  5KA2 A;  1PTV A;  2CM3 A;  2VEV A;  2ZMM A;  3F81 A;  3V0E A;  1PA9 A;  4NWG A;  2CNI A;  4QUN A;  2NT7 A;  1RPM A;  2E0T A;  3LJ8 A;  3QCG A; 
#chains in the Genus database with same CATH topology
 2B49 A;  1ZC0 A;  4GE5 A;  3MMJ A;  4WOH A;  4QAH A;  3MVN A;  2CM2 A;  2QCJ A;  1PTT A;  2NZ6 A;  4QDI A;  2I6M A;  2B4O A;  4BUC A;  2BV5 A;  1C87 A;  2F6W A;  2HC2 A;  2GC6 A;  4QF5 A;  1D5R A;  5LXQ B;  1YN9 A;  4WTY A;  5KA4 A;  1R6H A;  4ZI4 A;  3ZM2 A;  1FGS A;  2I42 A;  2AZR A;  3D42 A;  1Q6N A;  2CNG A;  3QCC A;  4RH5 A;  2HC1 A;  1G1H A;  5MMZ B;  2Y2F A;  2QCT A;  5KAD A;  1E0D A;  2QBP A;  1U24 A;  2P4D A;  1G7G A;  3D9C A;  4DGP A;  2GCB A;  1YFO A;  1YTN A;  3ZM6 A;  4MBB A;  3O5X A;  3NME A;  2GP0 A;  1NWL A;  3ZL8 A;  5I6V A;  1OEO X;  4PYH A;  1LYV A;  5BZX A;  3S3F A;  4QAP A;  3RGQ A;  3QKP A;  2VTE A;  4ZRT A;  2HB1 A;  4H1O A;  4D3P A;  1T49 A;  1A5Y A;  1OEM X;  1YTS A;  1KAV A;  3I80 A;  5GTJ A;  2HCM A;  1P3D A;  2H4V A;  2CNE A;  4GRZ A;  4OHI A;  2I4E A;  1G1G A;  1VHR A;  1OHC A;  1ZZW A;  1G4U S;  4QBE A;  4GS0 A;  1J6U A;  4NND A;  4NX8 A;  1E8C A;  2I6I A;  2F6Z A;  5A5E A;  3CWE A;  2UUP A;  5EHR A;  3QCF A;  1XXP A;  2XPC A;  5EHP A;  4JMK A;  4OHH A;  1W7K A;  2CM8 A;  2CMA A;  1JF7 A;  1PA1 A;  1C84 A;  1SUG A;  1YWF A;  4PVG A;  2H03 A;  1OEV A;  2AHS A;  2PBN A;  4GWF A;  1NO6 A;  1G4W R;  2H02 A;  2A3K A;  2I3R A;  1BZJ A;  2G6Z A;  1OHD A;  2QDC A;  1WAX A;  2WTZ A;  2G59 A;  2PSZ A;  1YGR A;  2F6T A;  1O5Z A;  3D1O A;  3N2A A;  5A5F A;  1T4J A;  2ZN7 A;  3I7Z A;  1YTW A;  4QUM A;  1PH0 A;  4GFU A;  5K9V A;  1C86 A;  1PXH A;  2PI7 A;  1OET A;  2Y67 A;  4BJO A;  5BX1 A;  1JBW A;  2I5X A;  1Q6T A;  2AM2 A;  1T48 A;  2Y1O A;  4BPC A;  2I6J A;  3ZM1 A;  1FPZ A;  1Q6P A;  1PTU A;  1RXD A;  1ECV A;  2GC5 A;  4Y2E A;  2I6O A;  5KA8 A;  4JBC A;  3O4U A;  4GRY A;  2QEP A;  5KA9 A;  2VEW A;  1FQ1 A;  2OUD A;  2VOR A;  1ONZ A;  1V3A A;  3H2X A;  2NLK A;  3ZMQ A;  3ZM0 A;  1UAG A;  3EMU A;  2C46 A;  1YPT A;  2PA5 A;  1Q6S A;  2CM7 A;  3QCZ A;  2M3V A;  3B7O A;  5K25 A;  2FJM A;  3V0F A;  1JLN A;  3HN7 A;  2FJN A;  4D3Q A;  3QCD A;  3S3E A;  1GG4 A;  5KAB A;  5KAC A;  1NL9 A;  3EU0 A;  4HJP A;  4R0S A;  1M3G A;  3EZZ A;  1GQY A;  1C88 A;  2CJZ A;  1QXK A;  1XM2 A;  2F46 A;  1XRI A;  2PT0 A;  2DXP A;  2HVL A;  4B04 A;  2VEY A;  1LAR A;  5HDE A;  5K23 A;  5M43 A;  4DGX A;  3O4T A;  2BIJ A;  2F70 A;  2AM1 A;  1FPR A;  3N0A A;  1G1F A;  5KA0 A;  2R0B A;  2QBQ A;  1WCH A;  1YZ4 A;  3I36 A;  3BLU A;  2Q47 A;  3F41 A;  2NT2 A;  2H4G A;  2NTA A;  2QDP A;  4JMJ A;  4OHL A;  4KI9 A;  3QCH A;  3EB1 A;  3A5K A;  4NYH A;  4WU3 A;  1I9S A;  1Q1M A;  2XJA A;  3S4O A;  2ESB A;  4GFV A;  5K22 A;  3QCJ A;  2CFV A;  1L8G A;  4HJQ A;  4HRF A;  4RDD A;  3QCI A;  1U26 A;  1J4X A;  5J8R A;  5KA1 A;  5K9W A;  4ICZ A;  2VEU A;  2I75 A;  4RKK A;  1GFY A;  4OHE A;  4J51 A;  5KA7 A;  2F71 A;  3V0H A;  4H34 A;  1OEU A;  1GWZ A;  2HNP A;  4JNB A;  3GXH A;  4TVV A;  3SME A;  2F6V A;  4ZIY A;  3A5J A;  1C83 A;  3OMH A;  2JJD A;  4R0T A;  4UAG A;  3QCE A;  1Q6J A;  3PYZ A;  2QBR A;  3BLT A;  3O4S A;  1GQQ A;  4YAA A;  4AZ1 A;  3M4U A;  3QCN A;  1XXV A;  3F9A A;  1BZC A;  2MBC A;  3ZV2 A;  3D1H A;  1P15 A;  3S3H A;  2FH7 A;  3RGO A;  2PQ5 A;  2JFG A;  2HXP A;  2B07 A;  1BZH A;  2J16 A;  4OHD A;  4RI5 A;  3PS5 A;  4WU2 A;  2Y66 A;  1PTY A;  3RO1 A;  3V0J A;  1W78 A;  4S0G A;  3ZM3 A;  5IBS A;  2WJP A;  2I4H A;  2QBS A;  1WRM A;  2BGE A;  2B4U A;  3D44 A;  5K24 A;  4ZN5 A;  3U96 A;  1NNY A;  4KYR A;  2GJT A;  2I4G A;  3GXG A;  2B3O A;  1C85 A;  1X24 A;  3BM8 A;  4KYQ A;  2CMB A;  3OLR A;  3QCL A;  4Y14 A;  1YGU A;  3QCM A;  3AWE A;  3S4E A;  2F6Y A;  2OC3 A;  3QCK A;  2SHP A;  4I8N A;  2Q05 A;  4YR8 B;  4IKC A;  2VEX A;  3ZM5 A;  3MOZ A;  1U25 A;  2P6X A;  1ZCK A;  1OHE A;  2IMG A;  3LK7 A;  2F6F A;  1KAK A;  1OES A;  2J17 A;  3O3L A;  4C13 A;  1EEO A;  1PYN A;  4RI4 A;  4C12 A;  5BZZ A;  2J16 B;  4CVL A;  2JFF A;  2QDM A;  1AAX A;  4GE2 A;  2H04 A;  1L8K A;  3MOW A;  2OOQ A;  4GE6 A;  5KAA A;  1QZ0 A;  4NWF A;  1I9T A;  4R30 A;  2CMC A;  3V0G A;  3ZMP A;  2WGP A;  1XBO A;  2HNQ A;  3EAX A;  5KA3 A;  4Z6B A;  1JBV A;  2Y68 A;  3AWF A;  4CVK A;  1MKP A;  2I1Y A;  2C7S A;  1I57 A;  2OZ5 A;  3UAG A;  4BUB A;  2B4P A;  3F99 A;  3BRH A;  5BUG A;  2B4S A;  2NV5 A;  4RH9 A;  3F9B A;  3SR9 A;  1EEN A;  1LQF A;  1NZ7 A;  3CM3 A;  2VTD A;  1NWE A;  1ONY A;  2A8B A;  2BZL A;  2Y96 A;  3QCB A;  5AWX A;  4D3R A;  3AWG A;  4CVM A;  3V0I A;  1G7F A;  2YDU A;  4HV4 A;  3RZ2 A;  1Q6M A;  1EEH A;  2X5O A;  5IBM A;  2BGD A;  2HY3 A;  4QBW A;  4ERC A;  2UAG A;  2VOS A;  2JFH A;  2CNH A;  2GCA A;  2H4K A;  2GWO A;  3QKQ A;  2RF6 A;  2CNF A;  3S3K A;  4RHG A;  1ZCL A;  3V0D A;  2I3U A;  2I6P A;  3D1Q A;  2F00 A;  5KA2 A;  1PTV A;  2CM3 A;  2VEV A;  2ZMM A;  3F81 A;  3V0E A;  1PA9 A;  3NRS A;  1P31 A;  4NWG A;  2CNI A;  4QUN A;  2NT7 A;  1RPM A;  2E0T A;  2UUO A;  3LJ8 A;  3QCG A; 
#chains in the Genus database with same CATH homology
 2B49 A;  1ZC0 A;  4GE5 A;  3MMJ A;  4WOH A;  4QAH A;  2CM2 A;  2QCJ A;  1PTT A;  2NZ6 A;  2I6M A;  2B4O A;  2BV5 A;  1C87 A;  2F6W A;  2HC2 A;  1D5R A;  5LXQ B;  1YN9 A;  4WTY A;  5KA4 A;  1R6H A;  4ZI4 A;  3ZM2 A;  2I42 A;  2AZR A;  3D42 A;  1Q6N A;  2CNG A;  3QCC A;  4RH5 A;  2HC1 A;  1G1H A;  5MMZ B;  2Y2F A;  2QCT A;  5KAD A;  2QBP A;  1U24 A;  2P4D A;  1G7G A;  3D9C A;  4DGP A;  1YFO A;  1YTN A;  4MBB A;  3O5X A;  3NME A;  2GP0 A;  1NWL A;  5I6V A;  1OEO X;  4PYH A;  1LYV A;  5BZX A;  3S3F A;  4QAP A;  3RGQ A;  3QKP A;  4ZRT A;  2HB1 A;  4H1O A;  4D3P A;  1T49 A;  1A5Y A;  1OEM X;  1YTS A;  1KAV A;  3I80 A;  5GTJ A;  2HCM A;  2H4V A;  2CNE A;  4GRZ A;  4OHI A;  2I4E A;  1G1G A;  1VHR A;  1OHC A;  1ZZW A;  1G4U S;  4QBE A;  4GS0 A;  4NND A;  4NX8 A;  2I6I A;  2F6Z A;  3CWE A;  5EHR A;  3QCF A;  1XXP A;  5EHP A;  4JMK A;  4OHH A;  2CM8 A;  2CMA A;  1JF7 A;  1PA1 A;  1C84 A;  1SUG A;  1YWF A;  4PVG A;  2H03 A;  1OEV A;  2AHS A;  2PBN A;  4GWF A;  1NO6 A;  1G4W R;  2H02 A;  2A3K A;  2I3R A;  1BZJ A;  2G6Z A;  1OHD A;  2QDC A;  1WAX A;  2G59 A;  2PSZ A;  1YGR A;  2F6T A;  3D1O A;  1T4J A;  2ZN7 A;  3I7Z A;  1YTW A;  4QUM A;  1PH0 A;  4GFU A;  5K9V A;  1C86 A;  1PXH A;  2PI7 A;  1OET A;  4BJO A;  5BX1 A;  2I5X A;  1Q6T A;  1T48 A;  4BPC A;  2I6J A;  3ZM1 A;  1FPZ A;  1Q6P A;  1PTU A;  1RXD A;  1ECV A;  4Y2E A;  2I6O A;  5KA8 A;  4JBC A;  3O4U A;  4GRY A;  2QEP A;  5KA9 A;  2VEW A;  1FQ1 A;  2OUD A;  1ONZ A;  1V3A A;  3H2X A;  2NLK A;  3ZMQ A;  3ZM0 A;  3EMU A;  2C46 A;  1YPT A;  2PA5 A;  1Q6S A;  2CM7 A;  2M3V A;  3B7O A;  5K25 A;  2FJM A;  3V0F A;  1JLN A;  2FJN A;  4D3Q A;  3QCD A;  3S3E A;  5KAB A;  5KAC A;  1NL9 A;  3EU0 A;  4HJP A;  4R0S A;  1M3G A;  3EZZ A;  1C88 A;  2CJZ A;  1QXK A;  1XM2 A;  2F46 A;  1XRI A;  2PT0 A;  2DXP A;  2HVL A;  4B04 A;  2VEY A;  1LAR A;  5HDE A;  5K23 A;  5M43 A;  4DGX A;  3O4T A;  2BIJ A;  2F70 A;  1FPR A;  3N0A A;  1G1F A;  5KA0 A;  2R0B A;  2QBQ A;  1WCH A;  1YZ4 A;  3I36 A;  2Q47 A;  3BLU A;  3F41 A;  2NT2 A;  2H4G A;  2NTA A;  2QDP A;  4JMJ A;  4OHL A;  4KI9 A;  3QCH A;  3EB1 A;  3A5K A;  4NYH A;  4WU3 A;  1I9S A;  1Q1M A;  3S4O A;  2ESB A;  4GFV A;  5K22 A;  3QCJ A;  2CFV A;  1L8G A;  4HJQ A;  4HRF A;  4RDD A;  3QCI A;  1U26 A;  1J4X A;  5J8R A;  5KA1 A;  5K9W A;  4ICZ A;  2VEU A;  2I75 A;  4RKK A;  1GFY A;  4OHE A;  4J51 A;  5KA7 A;  2F71 A;  3V0H A;  4H34 A;  1OEU A;  1GWZ A;  2HNP A;  4JNB A;  3GXH A;  4TVV A;  3SME A;  2F6V A;  3A5J A;  1C83 A;  3OMH A;  2JJD A;  4R0T A;  3QCE A;  1Q6J A;  2QBR A;  3BLT A;  3O4S A;  4YAA A;  4AZ1 A;  3M4U A;  3QCN A;  1XXV A;  3F9A A;  1BZC A;  2MBC A;  3ZV2 A;  3D1H A;  1P15 A;  3S3H A;  2FH7 A;  3RGO A;  2PQ5 A;  2HXP A;  2B07 A;  1BZH A;  2J16 A;  4OHD A;  4RI5 A;  3PS5 A;  4WU2 A;  1PTY A;  3RO1 A;  3V0J A;  4S0G A;  3ZM3 A;  5IBS A;  2I4H A;  2QBS A;  1WRM A;  2BGE A;  2B4U A;  3D44 A;  5K24 A;  4ZN5 A;  3U96 A;  1NNY A;  4KYR A;  2GJT A;  2I4G A;  3GXG A;  2B3O A;  1C85 A;  1X24 A;  3BM8 A;  4KYQ A;  2CMB A;  3OLR A;  3QCL A;  4Y14 A;  1YGU A;  3QCM A;  3AWE A;  3S4E A;  2F6Y A;  3QCK A;  2OC3 A;  2SHP A;  4I8N A;  2Q05 A;  4YR8 B;  4IKC A;  2VEX A;  3MOZ A;  1U25 A;  2P6X A;  1ZCK A;  1OHE A;  2IMG A;  2F6F A;  1KAK A;  1OES A;  2J17 A;  3O3L A;  1EEO A;  1PYN A;  4RI4 A;  5BZZ A;  2J16 B;  2QDM A;  1AAX A;  4GE2 A;  2H04 A;  1L8K A;  3MOW A;  2OOQ A;  4GE6 A;  5KAA A;  1QZ0 A;  4NWF A;  1I9T A;  4R30 A;  2CMC A;  3V0G A;  3ZMP A;  2WGP A;  1XBO A;  2HNQ A;  3EAX A;  5KA3 A;  4Z6B A;  3AWF A;  1MKP A;  2I1Y A;  2C7S A;  1I57 A;  2OZ5 A;  2B4P A;  3F99 A;  3BRH A;  5BUG A;  2B4S A;  2NV5 A;  4RH9 A;  3F9B A;  3SR9 A;  1EEN A;  1LQF A;  1NZ7 A;  3CM3 A;  1NWE A;  1ONY A;  2A8B A;  2BZL A;  2Y96 A;  3QCB A;  5AWX A;  4D3R A;  3AWG A;  3V0I A;  1G7F A;  2YDU A;  3RZ2 A;  1Q6M A;  5IBM A;  2BGD A;  2HY3 A;  4QBW A;  4ERC A;  2CNH A;  2H4K A;  2GWO A;  3QKQ A;  2RF6 A;  2CNF A;  3S3K A;  4RHG A;  1ZCL A;  3V0D A;  2I3U A;  2I6P A;  3D1Q A;  5KA2 A;  1PTV A;  2CM3 A;  2VEV A;  2ZMM A;  3F81 A;  3V0E A;  1PA9 A;  4NWG A;  2CNI A;  4QUN A;  2NT7 A;  1RPM A;  2E0T A;  3LJ8 A;  3QCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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