5KA9A

Protein tyrosine phosphatase 1b l192a mutant in complex with tcs401, open state
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
299
structure length
299
Chain Sequence
GHMASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFANFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 106
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka9A00
5HDEA 3QCHA 2H4GA 3O4UA 5KA0A 4NNDA 1YTWA 3H2XA 4S0GA 2PI7A 4H1OA 4GE2A 3OLRA 1L8GA 3OMHA 1C85A 5BZXA 4RHGA 1VHRA 3F9AA 1QXKA 2HCMA 4QBWA 4BJOA 1PTVA 2GWOA 5IBMA 5J8RA 3BRHA 2CM8A 2Y96A 4PVGA 1D5RA 1OEMX 1PA9A 2VEUA 4IKCA 2B4OA 2OZ5A 1YWFA 2CMAA 1ECVA 3I7ZA 2F6YA 3MMJA 2QBRA 1NZ7A 1ZCLA 3SMEA 1C88A 5BUGA 2PBNA 2VEXA 2QBPA 2MBCA 3QCMA 1YPTA 2BGDA 2JJDA 2A8BA 2F6ZA 4NWGA 4RH9A 1T48A 5MMZB 2PSZA 2BGEA 5K25A 5EHRA 2CMBA 2E0TA 2NZ6A 3QKQA 3RGQA 2HXPA 3I80A 2FJNA 3CM3A 3U96A 5K9WA 1PH0A 4Z6BA 2VEWA 4QUNA 1Q1MA 4TVVA 1A5YA 3LJ8A 4ZI4A 2J17A 3V0FA 4ZRTA 3D42A 2SHPA 1NWLA 2CMCA 5K9VA 2BV5A 1Q6MA 2J16B 1BZCA 2HY3A 1G7GA 2I6JA 2B4UA 5KACA 1OHCA 1AAXA 3EB1A 2AHSA 1OHEA 3F81A 3QCGA 2B3OA 3V0DA 3AWEA 2I6IA 1GFYA 3F41A 2CNEA 4ZN5A 3EZZA 2NLKA 2CFVA 1U24A 3ZMPA 3QKPA 3I36A 3S3HA 3RZ2A 1LYVA 4Y14A 1PTTA 4R0TA 2ESBA 5KA4A 4PYHA 4OHIA 2M3VA 2CM7A 2I42A 1G4WR 4GE6A 2NT2A 2PA5A 4HJQA 3QCEA 2B4PA 3EMUA 2I75A 2CM2A 4KYQA 4R0SA 2F6TA 3QCNA 5KA1A 1X24A 2F6FA 3ZM0A 3ZM2A 1Q6SA 4RI4A 3D44A 2I4GA 5GTJA 3ZM1A 3S3KA 1WCHA 1I9SA 3BM8A 3S3EA 1G4US 1R6HA 1FQ1A 5EHPA 4OHDA 1ZCKA 2I5XA 3S3FA 3O3LA 5KABA 3MOWA 4GE5A 5KA8A 2HVLA 2OC3A 4NX8A 5KA2A 3V0HA 1XBOA 2B07A 4R30A 1RXDA 3QCKA 1L8KA 1U25A 3QCBA 2ZN7A 3V0IA 1BZHA 1PYNA 1JF7A 3PS5A 4ERCA 2H03A 2IMGA 1I9TA 2NT7A 3RGOA 3ZM3A 2CJZA 2I4EA 1PXHA 2H4KA 2R0BA 2I3UA 3AWFA 1GWZA 1KAVA 3QCFA 4WOHA 3N0AA 2I6OA 1C84A 2CNGA 1FPZA 2VEYA 2I3RA 4RI5A 2CNHA 4OHHA 1RPMA 4KI9A 1NNYA 5LXQB 2NTAA 4BPCA 1XM2A 2QBSA 4RKKA 2I6PA 1T4JA 1ONZA 5KA7A 2F46A 3M4UA 2C46A 1QZ0A 2WGPA 2B4SA 1XRIA 2NV5A 1JLNA 3NMEA 1FPRA 4DGXA 3B7OA 1NWEA 1Q6PA 2DXPA 1C86A 3A5JA 1NL9A 2BIJA 1YGRA 3RO1A 3QCLA 4QBEA 1ZC0A 4DGPA 3O4TA 1OESA 2VEVA 5K22A 2F6WA 2I6MA 4MBBA 2ZMMA 3QCCA 2Y2FA 3S4OA 3MOZA 1WAXA 3A5KA 2A3KA 2FJMA 2CNIA 1YTSA 2QDPA 3EU0A 3V0JA 5BZZA 4JNBA 3EAXA 2G6ZA 1T49A 3D1HA 3BLUA 2CNFA 4NYHA 4JMJA 1KAKA 4GFUA 5I6VA 2QCTA 1Q6JA 5IBSA 4GWFA 2I1YA 1U26A 5KA9A 1YGUA 3D1OA 1XXPA 3F99A 4OHEA 3GXGA 4GS0A 3AWGA 1G1HA 4I8NA 3ZV2A 4GRZA 4QAPA 4GRYA 2Q47A 4WU3A 1SUGA 2H4VA 5M43A 1V3AA 1NO6A 4J51A 1Q6NA 2QBQA 2F70A 2B49A 1YFOA 2HB1A 1ZZWA 2H04A 2P6XA 4WU2A 2Q05A 1WRMA 1P15A 4D3RA 3V0EA 2YDUA 5K23A 3ZMQA 4YR8B 1YTNA 3QCJA 2OOQA 4B04A 5BX1A 1OEUA 4HRFA 3BLTA 2G59A 1BZJA 3S4EA 1OEOX 3QCIA 1C83A 2CM3A 2RF6A 1LQFA 2QDMA 1ONYA 1LARA 1PA1A 1PTUA 1YN9A 4D3PA 1I57A 3QCDA 2C7SA 4AZ1A 5K24A 4QUMA 5KA3A 1PTYA 1C87A 1EEOA 4JBCA 1Q6TA 2FH7A 3V0GA 2QCJA 1EENA 2GJTA 2PQ5A 1G1FA 3GXHA 1G1GA 1XXVA 4H34A 4Y2EA 1G7FA 3O4SA 2AZRA 3CWEA 4NWFA 3O5XA 5AWXA 3D1QA 2HNPA 5KADA 2PT0A 2J16A 4OHLA 2F6VA 2P4DA 4RDDA 2HC2A 1OETA 3D9CA 2HNQA 4GFVA 4KYRA 2BZLA 4HJPA 2QDCA 3SR9A 2GP0A 1YZ4A 2F71A 4YAAA 4ICZA 1OEVA 2QEPA 4D3QA 4JMKA 1OHDA 1MKPA 2H02A 2I4HA 1J4XA 3F9BA 4QAHA 5KAAA 4RH5A 2HC1A 2OUDA 4WTYA 1M3GA
chains in the Genus database with same CATH superfamily
5HDEA 3QCHA 2H4GA 3O4UA 5KA0A 1JBVA 4NNDA 1YTWA 2VOSA 3H2XA 4S0GA 2GCAA 2PI7A 4H1OA 4GE2A 2UAGA 3OLRA 1L8GA 3OMHA 3NRSA 1C85A 5BZXA 4RHGA 1VHRA 3F9AA 1QXKA 2HCMA 2UUPA 4QBWA 4BJOA 1PTVA 2GWOA 5IBMA 5J8RA 3BRHA 2CM8A 2Y96A 1EEHA 4PVGA 1D5RA 1OEMX 1PA9A 2VEUA 4IKCA 2OZ5A 1FGSA 2B4OA 1YWFA 2CMAA 1ECVA 3I7ZA 2F6YA 3MMJA 2QBRA 1NZ7A 1ZCLA 3SMEA 2AM2A 1C88A 5BUGA 2PBNA 2VEXA 2QBPA 2MBCA 3QCMA 1YPTA 4ZIYA 2BGDA 2JJDA 2A8BA 2F6ZA 3QCZA 4NWGA 4RH9A 1T48A 3N2AA 2X5OA 5MMZB 2PSZA 2BGEA 5K25A 3ZL8A 5EHRA 2CMBA 2E0TA 2NZ6A 3QKQA 3RGQA 2HXPA 4QF5A 3I80A 2FJNA 3CM3A 3U96A 1GG4A 5K9WA 1PH0A 4Z6BA 2VEWA 4QUNA 1Q1MA 4TVVA 1A5YA 3LJ8A 4ZI4A 2J17A 3V0FA 4ZRTA 3D42A 2SHPA 1NWLA 2CMCA 5K9VA 2BV5A 1Q6MA 2J16B 1BZCA 2HY3A 1G7GA 4CVMA 2I6JA 1W7KA 2B4UA 2Y1OA 5KACA 1OHCA 2AM1A 1AAXA 3EB1A 2AHSA 1OHEA 3F81A 3QCGA 2B3OA 3V0DA 3AWEA 2I6IA 1GFYA 3F41A 2CNEA 4ZN5A 3EZZA 2NLKA 2CFVA 1U24A 3ZMPA 3QKPA 2F00A 3I36A 3S3HA 3RZ2A 1LYVA 4Y14A 1PTTA 4R0TA 2ESBA 5KA4A 4PYHA 4OHIA 3ZM5A 2M3VA 2CM7A 2I42A 1G4WR 4GE6A 2NT2A 2PA5A 4HJQA 3QCEA 2B4PA 3EMUA 2I75A 2CM2A 4KYQA 4R0SA 2F6TA 3QCNA 5KA1A 1X24A 2F6FA 3ZM0A 3ZM2A 1Q6SA 4RI4A 3D44A 2I4GA 5GTJA 3ZM1A 3HN7A 4C12A 3S3KA 1WCHA 5A5FA 1I9SA 3BM8A 3S3EA 1G4US 1R6HA 1FQ1A 5EHPA 4OHDA 1ZCKA 2I5XA 3S3FA 3O3LA 5KABA 3MOWA 4GE5A 5KA8A 2HVLA 2OC3A 4NX8A 5KA2A 3V0HA 1XBOA 2B07A 4R30A 1RXDA 2WTZA 4BUBA 3QCKA 4BUCA 1L8KA 4CVKA 1U25A 3QCBA 2ZN7A 2Y66A 3V0IA 1BZHA 1PYNA 1JF7A 3PYZA 3PS5A 4ERCA 2WJPA 2H03A 2IMGA 2VORA 1I9TA 2NT7A 3RGOA 3ZM3A 2CJZA 2I4EA 1PXHA 2H4KA 2R0BA 2I3UA 1E8CA 3AWFA 1GWZA 1KAVA 3QCFA 4WOHA 3N0AA 2I6OA 3UAGA 1C84A 2CNGA 1FPZA 2VEYA 2I3RA 2Y68A 2CNHA 4OHHA 4RI5A 1RPMA 4KI9A 1NNYA 5LXQB 2NTAA 4BPCA 1XM2A 2QBSA 4RKKA 2I6PA 4UAGA 1T4JA 1ONZA 5KA7A 1UAGA 2F46A 4C13A 3M4UA 2C46A 1E0DA 1QZ0A 2WGPA 2B4SA 1XRIA 2NV5A 1JLNA 3NMEA 1FPRA 4DGXA 3B7OA 1NWEA 1W78A 1Q6PA 2DXPA 1C86A 3A5JA 1NL9A 2BIJA 1YGRA 3RO1A 3QCLA 2JFHA 4QBEA 1ZC0A 4DGPA 3O4TA 1OESA 2VEVA 5K22A 2F6WA 2I6MA 4MBBA 1JBWA 2ZMMA 3QCCA 1GQYA 2Y2FA 2JFGA 3S4OA 2JFFA 3MOZA 1WAXA 3A5KA 2A3KA 2FJMA 2CNIA 1YTSA 2QDPA 3EU0A 3V0JA 5BZZA 4JNBA 2Y67A 3EAXA 2G6ZA 1T49A 3D1HA 3BLUA 2CNFA 4NYHA 4JMJA 3ZM6A 1KAKA 4GFUA 5I6VA 2QCTA 1Q6JA 5IBSA 1GQQA 4GWFA 2GCBA 2I1YA 1U26A 5KA9A 4CVLA 1YGUA 3D1OA 1XXPA 3F99A 4OHEA 2VTDA 3GXGA 4GS0A 3AWGA 1G1HA 4I8NA 3ZV2A 4GRZA 4QAPA 4GRYA 2Q47A 4WU3A 1SUGA 2H4VA 5M43A 1V3AA 1NO6A 4J51A 1Q6NA 2QBQA 1J6UA 2F70A 2B49A 1YFOA 2HB1A 1ZZWA 2H04A 2P6XA 4WU2A 2Q05A 1WRMA 1P15A 4D3RA 3V0EA 2YDUA 5K23A 3ZMQA 4YR8B 1YTNA 3QCJA 2OOQA 4B04A 5BX1A 1OEUA 3MVNA 4HRFA 3BLTA 1P3DA 2G59A 2VTEA 2GC5A 1BZJA 3S4EA 1OEOX 3QCIA 1C83A 2CM3A 2RF6A 1LQFA 2QDMA 1ONYA 1LARA 1PA1A 1PTUA 1YN9A 1O5ZA 4D3PA 1I57A 3QCDA 2UUOA 2C7SA 4AZ1A 5K24A 4QUMA 5KA3A 3LK7A 1PTYA 1C87A 2GC6A 1EEOA 4JBCA 1Q6TA 2FH7A 3V0GA 2QCJA 1EENA 2GJTA 2PQ5A 1G1FA 3GXHA 1G1GA 1XXVA 4H34A 4Y2EA 1G7FA 3O4SA 2AZRA 3CWEA 4NWFA 3O5XA 5AWXA 3D1QA 2HNPA 5KADA 2PT0A 2J16A 4OHLA 2F6VA 2P4DA 4RDDA 2HC2A 1OETA 3D9CA 5A5EA 2XPCA 2HNQA 4GFVA 4KYRA 2XJAA 2BZLA 4QDIA 4HJPA 1P31A 2QDCA 3SR9A 2GP0A 1YZ4A 4HV4A 2F71A 4YAAA 4ICZA 1OEVA 2QEPA 4D3QA 4JMKA 1OHDA 1MKPA 2H02A 2I4HA 1J4XA 3F9BA 4QAHA 5KAAA 4RH5A 2HC1A 2OUDA 4WTYA 1M3GA
chains in the Genus database with same CATH topology
5HDEA 3QCHA 2H4GA 3O4UA 5KA0A 4NNDA 1YTWA 3H2XA 4S0GA 2PI7A 4H1OA 4GE2A 3OLRA 1L8GA 3OMHA 1C85A 5BZXA 4RHGA 1VHRA 3F9AA 1QXKA 2HCMA 4QBWA 4BJOA 1PTVA 2GWOA 5IBMA 5J8RA 3BRHA 2CM8A 2Y96A 4PVGA 1D5RA 1OEMX 1PA9A 2VEUA 4IKCA 2B4OA 2OZ5A 1YWFA 2CMAA 1ECVA 3I7ZA 2F6YA 3MMJA 2QBRA 1NZ7A 1ZCLA 3SMEA 1C88A 5BUGA 2PBNA 2VEXA 2QBPA 2MBCA 3QCMA 1YPTA 2BGDA 2JJDA 2A8BA 2F6ZA 4NWGA 4RH9A 1T48A 5MMZB 2PSZA 2BGEA 5K25A 5EHRA 2CMBA 2E0TA 2NZ6A 3QKQA 3RGQA 2HXPA 3I80A 2FJNA 3CM3A 3U96A 5K9WA 1PH0A 4Z6BA 2VEWA 4QUNA 1Q1MA 4TVVA 1A5YA 3LJ8A 4ZI4A 2J17A 3V0FA 4ZRTA 3D42A 2SHPA 1NWLA 2CMCA 5K9VA 2BV5A 1Q6MA 2J16B 1BZCA 2HY3A 1G7GA 2I6JA 2B4UA 5KACA 1OHCA 1AAXA 3EB1A 2AHSA 1OHEA 3F81A 3QCGA 2B3OA 3V0DA 3AWEA 2I6IA 1GFYA 3F41A 2CNEA 4ZN5A 3EZZA 2NLKA 2CFVA 1U24A 3ZMPA 3QKPA 3I36A 3S3HA 3RZ2A 1LYVA 4Y14A 1PTTA 4R0TA 2ESBA 5KA4A 4PYHA 4OHIA 2M3VA 2CM7A 2I42A 1G4WR 4GE6A 2NT2A 2PA5A 4HJQA 3QCEA 2B4PA 3EMUA 2I75A 2CM2A 4KYQA 4R0SA 2F6TA 3QCNA 5KA1A 1X24A 2F6FA 3ZM0A 3ZM2A 1Q6SA 4RI4A 3D44A 2I4GA 5GTJA 3ZM1A 3S3KA 1WCHA 1I9SA 3BM8A 3S3EA 1G4US 1R6HA 1FQ1A 5EHPA 4OHDA 1ZCKA 2I5XA 3S3FA 3O3LA 5KABA 3MOWA 4GE5A 5KA8A 2HVLA 2OC3A 4NX8A 5KA2A 3V0HA 1XBOA 2B07A 4R30A 1RXDA 3QCKA 1L8KA 1U25A 3QCBA 2ZN7A 3V0IA 1BZHA 1PYNA 1JF7A 3PS5A 4ERCA 2H03A 2IMGA 1I9TA 2NT7A 3RGOA 3ZM3A 2CJZA 2I4EA 1PXHA 2H4KA 2R0BA 2I3UA 3AWFA 1GWZA 1KAVA 3QCFA 4WOHA 3N0AA 2I6OA 1C84A 2CNGA 1FPZA 2VEYA 2I3RA 4RI5A 2CNHA 4OHHA 1RPMA 4KI9A 1NNYA 5LXQB 2NTAA 4BPCA 1XM2A 2QBSA 4RKKA 2I6PA 1T4JA 1ONZA 5KA7A 2F46A 3M4UA 2C46A 1QZ0A 2WGPA 2B4SA 1XRIA 2NV5A 1JLNA 3NMEA 1FPRA 4DGXA 3B7OA 1NWEA 1Q6PA 2DXPA 1C86A 3A5JA 1NL9A 2BIJA 1YGRA 3RO1A 3QCLA 4QBEA 1ZC0A 4DGPA 3O4TA 1OESA 2VEVA 5K22A 2F6WA 2I6MA 4MBBA 2ZMMA 3QCCA 2Y2FA 3S4OA 3MOZA 1WAXA 3A5KA 2A3KA 2FJMA 2CNIA 1YTSA 2QDPA 3EU0A 3V0JA 5BZZA 4JNBA 3EAXA 2G6ZA 1T49A 3D1HA 3BLUA 2CNFA 4NYHA 4JMJA 1KAKA 4GFUA 5I6VA 2QCTA 1Q6JA 5IBSA 4GWFA 2I1YA 1U26A 5KA9A 1YGUA 3D1OA 1XXPA 3F99A 4OHEA 3GXGA 4GS0A 3AWGA 1G1HA 4I8NA 3ZV2A 4GRZA 4QAPA 4GRYA 2Q47A 4WU3A 1SUGA 2H4VA 5M43A 1V3AA 1NO6A 4J51A 1Q6NA 2QBQA 2F70A 2B49A 1YFOA 2HB1A 1ZZWA 2H04A 2P6XA 4WU2A 2Q05A 1WRMA 1P15A 4D3RA 3V0EA 2YDUA 5K23A 3ZMQA 4YR8B 1YTNA 3QCJA 2OOQA 4B04A 5BX1A 1OEUA 4HRFA 3BLTA 2G59A 1BZJA 3S4EA 1OEOX 3QCIA 1C83A 2CM3A 2RF6A 1LQFA 2QDMA 1ONYA 1LARA 1PA1A 1PTUA 1YN9A 4D3PA 1I57A 3QCDA 2C7SA 4AZ1A 5K24A 4QUMA 5KA3A 1PTYA 1C87A 1EEOA 4JBCA 1Q6TA 2FH7A 3V0GA 2QCJA 1EENA 2GJTA 2PQ5A 1G1FA 3GXHA 1G1GA 1XXVA 4H34A 4Y2EA 1G7FA 3O4SA 2AZRA 3CWEA 4NWFA 3O5XA 5AWXA 3D1QA 2HNPA 5KADA 2PT0A 2J16A 4OHLA 2F6VA 2P4DA 4RDDA 2HC2A 1OETA 3D9CA 2HNQA 4GFVA 4KYRA 2BZLA 4HJPA 2QDCA 3SR9A 2GP0A 1YZ4A 2F71A 4YAAA 4ICZA 1OEVA 2QEPA 4D3QA 4JMKA 1OHDA 1MKPA 2H02A 2I4HA 1J4XA 3F9BA 4QAHA 5KAAA 4RH5A 2HC1A 2OUDA 4WTYA 1M3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HDE A;  3QCH A;  2H4G A;  3O4U A;  5KA0 A;  4NND A;  1YTW A;  3H2X A;  4S0G A;  2PI7 A;  4H1O A;  4GE2 A;  3OLR A;  1L8G A;  3OMH A;  1C85 A;  5BZX A;  4RHG A;  1VHR A;  3F9A A;  1QXK A;  2HCM A;  4QBW A;  4BJO A;  1PTV A;  2GWO A;  5IBM A;  5J8R A;  3BRH A;  2CM8 A;  2Y96 A;  4PVG A;  1D5R A;  1OEM X;  1PA9 A;  2VEU A;  4IKC A;  2B4O A;  2OZ5 A;  1YWF A;  2CMA A;  1ECV A;  3I7Z A;  2F6Y A;  3MMJ A;  2QBR A;  1NZ7 A;  1ZCL A;  3SME A;  1C88 A;  5BUG A;  2PBN A;  2VEX A;  2QBP A;  2MBC A;  3QCM A;  1YPT A;  2BGD A;  2JJD A;  2A8B A;  2F6Z A;  4NWG A;  4RH9 A;  1T48 A;  5MMZ B;  2PSZ A;  2BGE A;  5K25 A;  5EHR A;  2CMB A;  2E0T A;  2NZ6 A;  3QKQ A;  3RGQ A;  2HXP A;  3I80 A;  2FJN A;  3CM3 A;  3U96 A;  5K9W A;  1PH0 A;  4Z6B A;  2VEW A;  4QUN A;  1Q1M A;  4TVV A;  1A5Y A;  3LJ8 A;  4ZI4 A;  2J17 A;  3V0F A;  4ZRT A;  3D42 A;  2SHP A;  1NWL A;  2CMC A;  5K9V A;  2BV5 A;  1Q6M A;  2J16 B;  1BZC A;  2HY3 A;  1G7G A;  2I6J A;  2B4U A;  5KAC A;  1OHC A;  1AAX A;  3EB1 A;  2AHS A;  1OHE A;  3F81 A;  3QCG A;  2B3O A;  3V0D A;  3AWE A;  2I6I A;  1GFY A;  3F41 A;  2CNE A;  4ZN5 A;  3EZZ A;  2NLK A;  2CFV A;  1U24 A;  3ZMP A;  3QKP A;  3I36 A;  3S3H A;  3RZ2 A;  1LYV A;  4Y14 A;  1PTT A;  4R0T A;  2ESB A;  5KA4 A;  4PYH A;  4OHI A;  2M3V A;  2CM7 A;  2I42 A;  1G4W R;  4GE6 A;  2NT2 A;  2PA5 A;  4HJQ A;  3QCE A;  2B4P A;  3EMU A;  2I75 A;  2CM2 A;  4KYQ A;  4R0S A;  2F6T A;  3QCN A;  5KA1 A;  1X24 A;  2F6F A;  3ZM0 A;  3ZM2 A;  1Q6S A;  4RI4 A;  3D44 A;  2I4G A;  5GTJ A;  3ZM1 A;  3S3K A;  1WCH A;  1I9S A;  3BM8 A;  3S3E A;  1G4U S;  1R6H A;  1FQ1 A;  5EHP A;  4OHD A;  1ZCK A;  2I5X A;  3S3F A;  3O3L A;  5KAB A;  3MOW A;  4GE5 A;  5KA8 A;  2HVL A;  2OC3 A;  4NX8 A;  5KA2 A;  3V0H A;  1XBO A;  2B07 A;  4R30 A;  1RXD A;  3QCK A;  1L8K A;  1U25 A;  3QCB A;  2ZN7 A;  3V0I A;  1BZH A;  1PYN A;  1JF7 A;  3PS5 A;  4ERC A;  2H03 A;  2IMG A;  1I9T A;  2NT7 A;  3RGO A;  3ZM3 A;  2CJZ A;  2I4E A;  1PXH A;  2H4K A;  2R0B A;  2I3U A;  3AWF A;  1GWZ A;  1KAV A;  3QCF A;  4WOH A;  3N0A A;  2I6O A;  1C84 A;  2CNG A;  1FPZ A;  2VEY A;  2I3R A;  4RI5 A;  2CNH A;  4OHH A;  1RPM A;  4KI9 A;  1NNY A;  5LXQ B;  2NTA A;  4BPC A;  1XM2 A;  2QBS A;  4RKK A;  2I6P A;  1T4J A;  1ONZ A;  5KA7 A;  2F46 A;  3M4U A;  2C46 A;  1QZ0 A;  2WGP A;  2B4S A;  1XRI A;  2NV5 A;  1JLN A;  3NME A;  1FPR A;  4DGX A;  3B7O A;  1NWE A;  1Q6P A;  2DXP A;  1C86 A;  3A5J A;  1NL9 A;  2BIJ A;  1YGR A;  3RO1 A;  3QCL A;  4QBE A;  1ZC0 A;  4DGP A;  3O4T A;  1OES A;  2VEV A;  5K22 A;  2F6W A;  2I6M A;  4MBB A;  2ZMM A;  3QCC A;  2Y2F A;  3S4O A;  3MOZ A;  1WAX A;  3A5K A;  2A3K A;  2FJM A;  2CNI A;  1YTS A;  2QDP A;  3EU0 A;  3V0J A;  5BZZ A;  4JNB A;  3EAX A;  2G6Z A;  1T49 A;  3D1H A;  3BLU A;  2CNF A;  4NYH A;  4JMJ A;  1KAK A;  4GFU A;  5I6V A;  2QCT A;  1Q6J A;  5IBS A;  4GWF A;  2I1Y A;  1U26 A;  5KA9 A;  1YGU A;  3D1O A;  1XXP A;  3F99 A;  4OHE A;  3GXG A;  4GS0 A;  3AWG A;  1G1H A;  4I8N A;  3ZV2 A;  4GRZ A;  4QAP A;  4GRY A;  2Q47 A;  4WU3 A;  1SUG A;  2H4V A;  5M43 A;  1V3A A;  1NO6 A;  4J51 A;  1Q6N A;  2QBQ A;  2F70 A;  2B49 A;  1YFO A;  2HB1 A;  1ZZW A;  2H04 A;  2P6X A;  4WU2 A;  2Q05 A;  1WRM A;  1P15 A;  4D3R A;  3V0E A;  2YDU A;  5K23 A;  3ZMQ A;  4YR8 B;  1YTN A;  3QCJ A;  2OOQ A;  4B04 A;  5BX1 A;  1OEU A;  4HRF A;  3BLT A;  2G59 A;  1BZJ A;  3S4E A;  1OEO X;  3QCI A;  1C83 A;  2CM3 A;  2RF6 A;  1LQF A;  2QDM A;  1ONY A;  1LAR A;  1PA1 A;  1PTU A;  1YN9 A;  4D3P A;  1I57 A;  3QCD A;  2C7S A;  4AZ1 A;  5K24 A;  4QUM A;  5KA3 A;  1PTY A;  1C87 A;  1EEO A;  4JBC A;  1Q6T A;  2FH7 A;  3V0G A;  2QCJ A;  1EEN A;  2GJT A;  2PQ5 A;  1G1F A;  3GXH A;  1G1G A;  1XXV A;  4H34 A;  4Y2E A;  1G7F A;  3O4S A;  2AZR A;  3CWE A;  4NWF A;  3O5X A;  5AWX A;  3D1Q A;  2HNP A;  5KAD A;  2PT0 A;  2J16 A;  4OHL A;  2F6V A;  2P4D A;  4RDD A;  2HC2 A;  1OET A;  3D9C A;  2HNQ A;  4GFV A;  4KYR A;  2BZL A;  4HJP A;  2QDC A;  3SR9 A;  2GP0 A;  1YZ4 A;  2F71 A;  4YAA A;  4ICZ A;  1OEV A;  2QEP A;  4D3Q A;  4JMK A;  1OHD A;  1MKP A;  2H02 A;  2I4H A;  1J4X A;  3F9B A;  4QAH A;  5KAA A;  4RH5 A;  2HC1 A;  2OUD A;  4WTY A;  1M3G A; 
#chains in the Genus database with same CATH topology
 5HDE A;  3QCH A;  2H4G A;  3O4U A;  5KA0 A;  1JBV A;  4NND A;  1YTW A;  2VOS A;  3H2X A;  4S0G A;  2GCA A;  2PI7 A;  4H1O A;  4GE2 A;  2UAG A;  3OLR A;  1L8G A;  3OMH A;  3NRS A;  1C85 A;  5BZX A;  4RHG A;  1VHR A;  3F9A A;  1QXK A;  2HCM A;  2UUP A;  4QBW A;  4BJO A;  1PTV A;  2GWO A;  5IBM A;  5J8R A;  3BRH A;  2CM8 A;  2Y96 A;  1EEH A;  4PVG A;  1D5R A;  1OEM X;  1PA9 A;  2VEU A;  4IKC A;  2OZ5 A;  1FGS A;  2B4O A;  1YWF A;  2CMA A;  1ECV A;  3I7Z A;  2F6Y A;  3MMJ A;  2QBR A;  1NZ7 A;  1ZCL A;  3SME A;  2AM2 A;  1C88 A;  5BUG A;  2PBN A;  2VEX A;  2QBP A;  2MBC A;  3QCM A;  1YPT A;  4ZIY A;  2BGD A;  2JJD A;  2A8B A;  2F6Z A;  3QCZ A;  4NWG A;  4RH9 A;  1T48 A;  3N2A A;  2X5O A;  5MMZ B;  2PSZ A;  2BGE A;  5K25 A;  3ZL8 A;  5EHR A;  2CMB A;  2E0T A;  2NZ6 A;  3QKQ A;  3RGQ A;  2HXP A;  4QF5 A;  3I80 A;  2FJN A;  3CM3 A;  3U96 A;  1GG4 A;  5K9W A;  1PH0 A;  4Z6B A;  2VEW A;  4QUN A;  1Q1M A;  4TVV A;  1A5Y A;  3LJ8 A;  4ZI4 A;  2J17 A;  3V0F A;  4ZRT A;  3D42 A;  2SHP A;  1NWL A;  2CMC A;  5K9V A;  2BV5 A;  1Q6M A;  2J16 B;  1BZC A;  2HY3 A;  1G7G A;  4CVM A;  2I6J A;  1W7K A;  2B4U A;  2Y1O A;  5KAC A;  1OHC A;  2AM1 A;  1AAX A;  3EB1 A;  2AHS A;  1OHE A;  3F81 A;  3QCG A;  2B3O A;  3V0D A;  3AWE A;  2I6I A;  1GFY A;  3F41 A;  2CNE A;  4ZN5 A;  3EZZ A;  2NLK A;  2CFV A;  1U24 A;  3ZMP A;  3QKP A;  2F00 A;  3I36 A;  3S3H A;  3RZ2 A;  1LYV A;  4Y14 A;  1PTT A;  4R0T A;  2ESB A;  5KA4 A;  4PYH A;  4OHI A;  3ZM5 A;  2M3V A;  2CM7 A;  2I42 A;  1G4W R;  4GE6 A;  2NT2 A;  2PA5 A;  4HJQ A;  3QCE A;  2B4P A;  3EMU A;  2I75 A;  2CM2 A;  4KYQ A;  4R0S A;  2F6T A;  3QCN A;  5KA1 A;  1X24 A;  2F6F A;  3ZM0 A;  3ZM2 A;  1Q6S A;  4RI4 A;  3D44 A;  2I4G A;  5GTJ A;  3ZM1 A;  3HN7 A;  4C12 A;  3S3K A;  1WCH A;  5A5F A;  1I9S A;  3BM8 A;  3S3E A;  1G4U S;  1R6H A;  1FQ1 A;  5EHP A;  4OHD A;  1ZCK A;  2I5X A;  3S3F A;  3O3L A;  5KAB A;  3MOW A;  4GE5 A;  5KA8 A;  2HVL A;  2OC3 A;  4NX8 A;  5KA2 A;  3V0H A;  1XBO A;  2B07 A;  4R30 A;  1RXD A;  2WTZ A;  4BUB A;  3QCK A;  4BUC A;  1L8K A;  4CVK A;  1U25 A;  3QCB A;  2ZN7 A;  2Y66 A;  3V0I A;  1BZH A;  1PYN A;  1JF7 A;  3PYZ A;  3PS5 A;  4ERC A;  2WJP A;  2H03 A;  2IMG A;  2VOR A;  1I9T A;  2NT7 A;  3RGO A;  3ZM3 A;  2CJZ A;  2I4E A;  1PXH A;  2H4K A;  2R0B A;  2I3U A;  1E8C A;  3AWF A;  1GWZ A;  1KAV A;  3QCF A;  4WOH A;  3N0A A;  2I6O A;  3UAG A;  1C84 A;  2CNG A;  1FPZ A;  2VEY A;  2I3R A;  2Y68 A;  2CNH A;  4OHH A;  4RI5 A;  1RPM A;  4KI9 A;  1NNY A;  5LXQ B;  2NTA A;  4BPC A;  1XM2 A;  2QBS A;  4RKK A;  2I6P A;  4UAG A;  1T4J A;  1ONZ A;  5KA7 A;  1UAG A;  2F46 A;  4C13 A;  3M4U A;  2C46 A;  1E0D A;  1QZ0 A;  2WGP A;  2B4S A;  1XRI A;  2NV5 A;  1JLN A;  3NME A;  1FPR A;  4DGX A;  3B7O A;  1NWE A;  1W78 A;  1Q6P A;  2DXP A;  1C86 A;  3A5J A;  1NL9 A;  2BIJ A;  1YGR A;  3RO1 A;  3QCL A;  2JFH A;  4QBE A;  1ZC0 A;  4DGP A;  3O4T A;  1OES A;  2VEV A;  5K22 A;  2F6W A;  2I6M A;  4MBB A;  1JBW A;  2ZMM A;  3QCC A;  1GQY A;  2Y2F A;  2JFG A;  3S4O A;  2JFF A;  3MOZ A;  1WAX A;  3A5K A;  2A3K A;  2FJM A;  2CNI A;  1YTS A;  2QDP A;  3EU0 A;  3V0J A;  5BZZ A;  4JNB A;  2Y67 A;  3EAX A;  2G6Z A;  1T49 A;  3D1H A;  3BLU A;  2CNF A;  4NYH A;  4JMJ A;  3ZM6 A;  1KAK A;  4GFU A;  5I6V A;  2QCT A;  1Q6J A;  5IBS A;  1GQQ A;  4GWF A;  2GCB A;  2I1Y A;  1U26 A;  5KA9 A;  4CVL A;  1YGU A;  3D1O A;  1XXP A;  3F99 A;  4OHE A;  2VTD A;  3GXG A;  4GS0 A;  3AWG A;  1G1H A;  4I8N A;  3ZV2 A;  4GRZ A;  4QAP A;  4GRY A;  2Q47 A;  4WU3 A;  1SUG A;  2H4V A;  5M43 A;  1V3A A;  1NO6 A;  4J51 A;  1Q6N A;  2QBQ A;  1J6U A;  2F70 A;  2B49 A;  1YFO A;  2HB1 A;  1ZZW A;  2H04 A;  2P6X A;  4WU2 A;  2Q05 A;  1WRM A;  1P15 A;  4D3R A;  3V0E A;  2YDU A;  5K23 A;  3ZMQ A;  4YR8 B;  1YTN A;  3QCJ A;  2OOQ A;  4B04 A;  5BX1 A;  1OEU A;  3MVN A;  4HRF A;  3BLT A;  1P3D A;  2G59 A;  2VTE A;  2GC5 A;  1BZJ A;  3S4E A;  1OEO X;  3QCI A;  1C83 A;  2CM3 A;  2RF6 A;  1LQF A;  2QDM A;  1ONY A;  1LAR A;  1PA1 A;  1PTU A;  1YN9 A;  1O5Z A;  4D3P A;  1I57 A;  3QCD A;  2UUO A;  2C7S A;  4AZ1 A;  5K24 A;  4QUM A;  5KA3 A;  3LK7 A;  1PTY A;  1C87 A;  2GC6 A;  1EEO A;  4JBC A;  1Q6T A;  2FH7 A;  3V0G A;  2QCJ A;  1EEN A;  2GJT A;  2PQ5 A;  1G1F A;  3GXH A;  1G1G A;  1XXV A;  4H34 A;  4Y2E A;  1G7F A;  3O4S A;  2AZR A;  3CWE A;  4NWF A;  3O5X A;  5AWX A;  3D1Q A;  2HNP A;  5KAD A;  2PT0 A;  2J16 A;  4OHL A;  2F6V A;  2P4D A;  4RDD A;  2HC2 A;  1OET A;  3D9C A;  5A5E A;  2XPC A;  2HNQ A;  4GFV A;  4KYR A;  2XJA A;  2BZL A;  4QDI A;  4HJP A;  1P31 A;  2QDC A;  3SR9 A;  2GP0 A;  1YZ4 A;  4HV4 A;  2F71 A;  4YAA A;  4ICZ A;  1OEV A;  2QEP A;  4D3Q A;  4JMK A;  1OHD A;  1MKP A;  2H02 A;  2I4H A;  1J4X A;  3F9B A;  4QAH A;  5KAA A;  4RH5 A;  2HC1 A;  2OUD A;  4WTY A;  1M3G A; 
#chains in the Genus database with same CATH homology
 5HDE A;  3QCH A;  2H4G A;  3O4U A;  5KA0 A;  4NND A;  1YTW A;  3H2X A;  4S0G A;  2PI7 A;  4H1O A;  4GE2 A;  3OLR A;  1L8G A;  3OMH A;  1C85 A;  5BZX A;  4RHG A;  1VHR A;  3F9A A;  1QXK A;  2HCM A;  4QBW A;  4BJO A;  1PTV A;  2GWO A;  5IBM A;  5J8R A;  3BRH A;  2CM8 A;  2Y96 A;  4PVG A;  1D5R A;  1OEM X;  1PA9 A;  2VEU A;  4IKC A;  2B4O A;  2OZ5 A;  1YWF A;  2CMA A;  1ECV A;  3I7Z A;  2F6Y A;  3MMJ A;  2QBR A;  1NZ7 A;  1ZCL A;  3SME A;  1C88 A;  5BUG A;  2PBN A;  2VEX A;  2QBP A;  2MBC A;  3QCM A;  1YPT A;  2BGD A;  2JJD A;  2A8B A;  2F6Z A;  4NWG A;  4RH9 A;  1T48 A;  5MMZ B;  2PSZ A;  2BGE A;  5K25 A;  5EHR A;  2CMB A;  2E0T A;  2NZ6 A;  3QKQ A;  3RGQ A;  2HXP A;  3I80 A;  2FJN A;  3CM3 A;  3U96 A;  5K9W A;  1PH0 A;  4Z6B A;  2VEW A;  4QUN A;  1Q1M A;  4TVV A;  1A5Y A;  3LJ8 A;  4ZI4 A;  2J17 A;  3V0F A;  4ZRT A;  3D42 A;  2SHP A;  1NWL A;  2CMC A;  5K9V A;  2BV5 A;  1Q6M A;  2J16 B;  1BZC A;  2HY3 A;  1G7G A;  2I6J A;  2B4U A;  5KAC A;  1OHC A;  1AAX A;  3EB1 A;  2AHS A;  1OHE A;  3F81 A;  3QCG A;  2B3O A;  3V0D A;  3AWE A;  2I6I A;  1GFY A;  3F41 A;  2CNE A;  4ZN5 A;  3EZZ A;  2NLK A;  2CFV A;  1U24 A;  3ZMP A;  3QKP A;  3I36 A;  3S3H A;  3RZ2 A;  1LYV A;  4Y14 A;  1PTT A;  4R0T A;  2ESB A;  5KA4 A;  4PYH A;  4OHI A;  2M3V A;  2CM7 A;  2I42 A;  1G4W R;  4GE6 A;  2NT2 A;  2PA5 A;  4HJQ A;  3QCE A;  2B4P A;  3EMU A;  2I75 A;  2CM2 A;  4KYQ A;  4R0S A;  2F6T A;  3QCN A;  5KA1 A;  1X24 A;  2F6F A;  3ZM0 A;  3ZM2 A;  1Q6S A;  4RI4 A;  3D44 A;  2I4G A;  5GTJ A;  3ZM1 A;  3S3K A;  1WCH A;  1I9S A;  3BM8 A;  3S3E A;  1G4U S;  1R6H A;  1FQ1 A;  5EHP A;  4OHD A;  1ZCK A;  2I5X A;  3S3F A;  3O3L A;  5KAB A;  3MOW A;  4GE5 A;  5KA8 A;  2HVL A;  2OC3 A;  4NX8 A;  5KA2 A;  3V0H A;  1XBO A;  2B07 A;  4R30 A;  1RXD A;  3QCK A;  1L8K A;  1U25 A;  3QCB A;  2ZN7 A;  3V0I A;  1BZH A;  1PYN A;  1JF7 A;  3PS5 A;  4ERC A;  2H03 A;  2IMG A;  1I9T A;  2NT7 A;  3RGO A;  3ZM3 A;  2CJZ A;  2I4E A;  1PXH A;  2H4K A;  2R0B A;  2I3U A;  3AWF A;  1GWZ A;  1KAV A;  3QCF A;  4WOH A;  3N0A A;  2I6O A;  1C84 A;  2CNG A;  1FPZ A;  2VEY A;  2I3R A;  4RI5 A;  2CNH A;  4OHH A;  1RPM A;  4KI9 A;  1NNY A;  5LXQ B;  2NTA A;  4BPC A;  1XM2 A;  2QBS A;  4RKK A;  2I6P A;  1T4J A;  1ONZ A;  5KA7 A;  2F46 A;  3M4U A;  2C46 A;  1QZ0 A;  2WGP A;  2B4S A;  1XRI A;  2NV5 A;  1JLN A;  3NME A;  1FPR A;  4DGX A;  3B7O A;  1NWE A;  1Q6P A;  2DXP A;  1C86 A;  3A5J A;  1NL9 A;  2BIJ A;  1YGR A;  3RO1 A;  3QCL A;  4QBE A;  1ZC0 A;  4DGP A;  3O4T A;  1OES A;  2VEV A;  5K22 A;  2F6W A;  2I6M A;  4MBB A;  2ZMM A;  3QCC A;  2Y2F A;  3S4O A;  3MOZ A;  1WAX A;  3A5K A;  2A3K A;  2FJM A;  2CNI A;  1YTS A;  2QDP A;  3EU0 A;  3V0J A;  5BZZ A;  4JNB A;  3EAX A;  2G6Z A;  1T49 A;  3D1H A;  3BLU A;  2CNF A;  4NYH A;  4JMJ A;  1KAK A;  4GFU A;  5I6V A;  2QCT A;  1Q6J A;  5IBS A;  4GWF A;  2I1Y A;  1U26 A;  5KA9 A;  1YGU A;  3D1O A;  1XXP A;  3F99 A;  4OHE A;  3GXG A;  4GS0 A;  3AWG A;  1G1H A;  4I8N A;  3ZV2 A;  4GRZ A;  4QAP A;  4GRY A;  2Q47 A;  4WU3 A;  1SUG A;  2H4V A;  5M43 A;  1V3A A;  1NO6 A;  4J51 A;  1Q6N A;  2QBQ A;  2F70 A;  2B49 A;  1YFO A;  2HB1 A;  1ZZW A;  2H04 A;  2P6X A;  4WU2 A;  2Q05 A;  1WRM A;  1P15 A;  4D3R A;  3V0E A;  2YDU A;  5K23 A;  3ZMQ A;  4YR8 B;  1YTN A;  3QCJ A;  2OOQ A;  4B04 A;  5BX1 A;  1OEU A;  4HRF A;  3BLT A;  2G59 A;  1BZJ A;  3S4E A;  1OEO X;  3QCI A;  1C83 A;  2CM3 A;  2RF6 A;  1LQF A;  2QDM A;  1ONY A;  1LAR A;  1PA1 A;  1PTU A;  1YN9 A;  4D3P A;  1I57 A;  3QCD A;  2C7S A;  4AZ1 A;  5K24 A;  4QUM A;  5KA3 A;  1PTY A;  1C87 A;  1EEO A;  4JBC A;  1Q6T A;  2FH7 A;  3V0G A;  2QCJ A;  1EEN A;  2GJT A;  2PQ5 A;  1G1F A;  3GXH A;  1G1G A;  1XXV A;  4H34 A;  4Y2E A;  1G7F A;  3O4S A;  2AZR A;  3CWE A;  4NWF A;  3O5X A;  5AWX A;  3D1Q A;  2HNP A;  5KAD A;  2PT0 A;  2J16 A;  4OHL A;  2F6V A;  2P4D A;  4RDD A;  2HC2 A;  1OET A;  3D9C A;  2HNQ A;  4GFV A;  4KYR A;  2BZL A;  4HJP A;  2QDC A;  3SR9 A;  2GP0 A;  1YZ4 A;  2F71 A;  4YAA A;  4ICZ A;  1OEV A;  2QEP A;  4D3Q A;  4JMK A;  1OHD A;  1MKP A;  2H02 A;  2I4H A;  1J4X A;  3F9B A;  4QAH A;  5KAA A;  4RH5 A;  2HC1 A;  2OUD A;  4WTY A;  1M3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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