5KN8A

Muty n-terminal domain in complex with undamaged dna
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
222
structure length
222
Chain Sequence
FPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenine DNA glycosylase
publication title Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Hydrolase/dna
total genus 87
structure length 222
sequence length 222
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2016-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5kn8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 5kn8A01
4OFEA 4E9FA 2YG8A 1KO9A 1MUNA 1PU6A 3KTUA 3G0QA 2I5WA 4YOQA 1WEGA 1EBMA 3IHOA 1LWWA 2NOFA 3CVSA 1LMZA 5KN8A 3FSPA 2NOBA 4EJZA 4YPRA 4EA5A 1ORPA 3OH6A 3OH9A 1KG5A 2XHIA 1WEFA 1YQKA 1KG6A 5CHZA 4PIIA 4DK9A 1N3CA 3I0XA 2NOZA 1KEAA 4EW4A 1M3HA 4OFHA 1YQRA 1MUDA 1DIZA 2NOLA 1PVSA 4AI5A 3CW7A 1MPGA 1KG3A 3FHGA 4E9EA 1PU7A 4HSBA 1N3AA 2H56A 1PU8A 2JG6A 2NOEA 1N39A 1KG7A 4B24A 2JHNA 1ORNA 4EA4A 4B22A 3S6IA 4EW0A 2NOIA 5KN9A 1NGNA 1P59A 4B23A 3I0WA 1P7MA 3CWAA 3N0UA 3D4VA 1KG4A 3CVTA 1RRSA 1XQPA 1KQJA 2JHJA 1XG7A 3KNTA 3CWSA 3OGDA 4UNFA 3FHFA 1XQOA 4E9GA 2OFKA 5DPKA 2NOHA 4YPHA 4B21A 1HU0A 3CWTA 2YG9A 4UOBA 1YQMA 4E9HA 1VRLA 3N5NX 1LWYA 3IH7A 4AI4A 3F10A 1KG2A 4OFAA 3CWUA 4EJYA 1YQLA 4AIAA 4EVVA 1LWVA 1FN7A 5AN4A 1MUYA 1RRQA 1M3QA 2ABKA 1WEIA 3F0ZA 2OFIA 1NKUA
chains in the Genus database with same CATH superfamily
4OFEA 4E9FA 5FRMA 2YG8A 1KO9A 1MUNA 3OYIA 1PU6A 3OYGA 3KTUA 3G0QA 4BE0A 2I5WA 4NZGA 4YOQA 3OYFA 1WEGA 1EBMA 3IHOA 1LWWA 2NOFA 4BE1A 2JPSA 3CVSA 1LMZA 5KN8A 3FSPA 2NOBA 4EJZA 4YPRA 4EA5A 4BDZA 1ORPA 2OFIA 3OH6A 4ZTFA 3OH9A 2W04A 1KG5A 5FRNA 2XHIA 1WEFA 1YQKA 1KG6A 5CHZA 4PIIA 4DK9A 3OYMA 3I0XA 1N3CA 3OYHA 2NOZA 1KEAA 5FROA 4EW4A 1M3HA 4OFHA 3OS0A 1MUDA 1YQRA 2V75A 1DIZA 2NOLA 1PVSA 4AI5A 3CW7A 3L2QA 1MPGA 3S3NA 1KG3A 4E7IA 3FHGA 4E9EA 4BDYA 1PU7A 4HSBA 1N3AA 2H56A 1PU8A 2JG6A 4IKFA 2NOEA 1N39A 1KG7A 4B24A 4E7HA 1U84A 4E7JA 2JHNA 1ORNA 4EA4A 4B22A 3S6IA 4ZTJA 4EW0A 2NOIA 5KN9A 1NGNA 1P59A 4B23A 3I0WA 1P7MA 3OYAA 3CWAA 3N0UA 3D4VA 3NNQA 1KG4A 3OS2A 3OYNA 1XQPA 1KQJA 2JHJA 1RRSA 3CVTA 1XG7A 3OYKA 3KNTA 3CWSA 3OGDA 4UNFA 3FHFA 3OYJA 1XQOA 4E9GA 3S3OA 3OYBA 3R2XC 2OFKA 5DPKA 2NOHA 4YPHA 4B21A 4BE2A 1HU0A 3CWTA 2YG9A 3OY9A 4UOBA 1YQMA 4BACA 4E9HA 3N5NX 1VRLA 1LWYA 3IH7A 3L2WA 3L2UA 4E7KA 4AI4A 3F10A 1KG2A 4OFAA 3CWUA 4EJYA 3L2RA 1YQLA 4AIAA 4EVVA 3VW4A 1LWVA 1FN7A 5AN4A 2W03A 3OYEA 3OYCA 3OYDA 3L2VA 1MUYA 1RRQA 1M3QA 3LCNA 2ABKA 3OS1A 4E7LA 1WEIA 3F0ZA 3OYLA 1NKUA 3S3MA
chains in the Genus database with same CATH topology
4OFEA 4E9FA 2YG8A 1KO9A 1MUNA 1PU6A 3KTUA 3G0QA 2I5WA 4YOQA 1WEGA 1EBMA 3IHOA 1LWWA 2NOFA 3CVSA 1LMZA 5KN8A 3FSPA 2NOBA 4EJZA 4YPRA 4EA5A 1ORPA 3OH6A 3OH9A 1KG5A 2XHIA 1WEFA 1YQKA 1KG6A 5CHZA 4PIIA 4DK9A 1N3CA 3I0XA 2NOZA 1KEAA 4EW4A 1M3HA 4OFHA 1YQRA 1MUDA 1DIZA 2NOLA 1PVSA 4AI5A 3CW7A 1MPGA 1KG3A 3FHGA 4E9EA 1PU7A 4HSBA 1N3AA 2H56A 1PU8A 2JG6A 2NOEA 1N39A 1KG7A 4B24A 2JHNA 1ORNA 4EA4A 4B22A 3S6IA 4EW0A 2NOIA 5KN9A 1NGNA 1P59A 4B23A 3I0WA 1P7MA 3CWAA 3N0UA 3D4VA 1KG4A 3CVTA 1RRSA 1XQPA 1KQJA 2JHJA 1XG7A 3KNTA 3CWSA 3OGDA 4UNFA 3FHFA 1XQOA 4E9GA 2OFKA 5DPKA 2NOHA 4YPHA 4B21A 1HU0A 3CWTA 2YG9A 4UOBA 1YQMA 4E9HA 1VRLA 3N5NX 1LWYA 3IH7A 4AI4A 3F10A 1KG2A 4OFAA 3CWUA 4EJYA 1YQLA 4AIAA 4EVVA 1LWVA 1FN7A 5AN4A 1MUYA 1RRQA 1M3QA 2ABKA 1WEIA 3F0ZA 2OFIA 1NKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OFE A;  4E9F A;  2YG8 A;  1KO9 A;  1MUN A;  1PU6 A;  3KTU A;  3G0Q A;  2I5W A;  4YOQ A;  1WEG A;  1EBM A;  3IHO A;  1LWW A;  2NOF A;  3CVS A;  1LMZ A;  5KN8 A;  3FSP A;  2NOB A;  4EJZ A;  4YPR A;  4EA5 A;  1ORP A;  3OH6 A;  3OH9 A;  1KG5 A;  2XHI A;  1WEF A;  1YQK A;  1KG6 A;  5CHZ A;  4PII A;  4DK9 A;  1N3C A;  3I0X A;  2NOZ A;  1KEA A;  4EW4 A;  1M3H A;  4OFH A;  1YQR A;  1MUD A;  1DIZ A;  2NOL A;  1PVS A;  4AI5 A;  3CW7 A;  1MPG A;  1KG3 A;  3FHG A;  4E9E A;  1PU7 A;  4HSB A;  1N3A A;  2H56 A;  1PU8 A;  2JG6 A;  2NOE A;  1N39 A;  1KG7 A;  4B24 A;  2JHN A;  1ORN A;  4EA4 A;  4B22 A;  3S6I A;  4EW0 A;  2NOI A;  5KN9 A;  1NGN A;  1P59 A;  4B23 A;  3I0W A;  1P7M A;  3CWA A;  3N0U A;  3D4V A;  1KG4 A;  3CVT A;  1RRS A;  1XQP A;  1KQJ A;  2JHJ A;  1XG7 A;  3KNT A;  3CWS A;  3OGD A;  4UNF A;  3FHF A;  1XQO A;  4E9G A;  2OFK A;  5DPK A;  2NOH A;  4YPH A;  4B21 A;  1HU0 A;  3CWT A;  2YG9 A;  4UOB A;  1YQM A;  4E9H A;  1VRL A;  3N5N X;  1LWY A;  3IH7 A;  4AI4 A;  3F10 A;  1KG2 A;  4OFA A;  3CWU A;  4EJY A;  1YQL A;  4AIA A;  4EVV A;  1LWV A;  1FN7 A;  5AN4 A;  1MUY A;  1RRQ A;  1M3Q A;  2ABK A;  1WEI A;  3F0Z A;  2OFI A;  1NKU A; 
#chains in the Genus database with same CATH topology
 4OFE A;  4E9F A;  5FRM A;  2YG8 A;  1KO9 A;  1MUN A;  3OYI A;  1PU6 A;  3OYG A;  3KTU A;  3G0Q A;  4BE0 A;  2I5W A;  4NZG A;  4YOQ A;  3OYF A;  1WEG A;  1EBM A;  3IHO A;  1LWW A;  2NOF A;  4BE1 A;  2JPS A;  3CVS A;  1LMZ A;  5KN8 A;  3FSP A;  2NOB A;  4EJZ A;  4YPR A;  4EA5 A;  4BDZ A;  1ORP A;  2OFI A;  3OH6 A;  4ZTF A;  3OH9 A;  2W04 A;  1KG5 A;  5FRN A;  2XHI A;  1WEF A;  1YQK A;  1KG6 A;  5CHZ A;  4PII A;  4DK9 A;  3OYM A;  3I0X A;  1N3C A;  3OYH A;  2NOZ A;  1KEA A;  5FRO A;  4EW4 A;  1M3H A;  4OFH A;  3OS0 A;  1MUD A;  1YQR A;  2V75 A;  1DIZ A;  2NOL A;  1PVS A;  4AI5 A;  3CW7 A;  3L2Q A;  1MPG A;  3S3N A;  1KG3 A;  4E7I A;  3FHG A;  4E9E A;  4BDY A;  1PU7 A;  4HSB A;  1N3A A;  2H56 A;  1PU8 A;  2JG6 A;  4IKF A;  2NOE A;  1N39 A;  1KG7 A;  4B24 A;  4E7H A;  1U84 A;  4E7J A;  2JHN A;  1ORN A;  4EA4 A;  4B22 A;  3S6I A;  4ZTJ A;  4EW0 A;  2NOI A;  5KN9 A;  1NGN A;  1P59 A;  4B23 A;  3I0W A;  1P7M A;  3OYA A;  3CWA A;  3N0U A;  3D4V A;  3NNQ A;  1KG4 A;  3OS2 A;  3OYN A;  1XQP A;  1KQJ A;  2JHJ A;  1RRS A;  3CVT A;  1XG7 A;  3OYK A;  3KNT A;  3CWS A;  3OGD A;  4UNF A;  3FHF A;  3OYJ A;  1XQO A;  4E9G A;  3S3O A;  3OYB A;  3R2X C;  2OFK A;  5DPK A;  2NOH A;  4YPH A;  4B21 A;  4BE2 A;  1HU0 A;  3CWT A;  2YG9 A;  3OY9 A;  4UOB A;  1YQM A;  4BAC A;  4E9H A;  3N5N X;  1VRL A;  1LWY A;  3IH7 A;  3L2W A;  3L2U A;  4E7K A;  4AI4 A;  3F10 A;  1KG2 A;  4OFA A;  3CWU A;  4EJY A;  3L2R A;  1YQL A;  4AIA A;  4EVV A;  3VW4 A;  1LWV A;  1FN7 A;  5AN4 A;  2W03 A;  3OYE A;  3OYC A;  3OYD A;  3L2V A;  1MUY A;  1RRQ A;  1M3Q A;  3LCN A;  2ABK A;  3OS1 A;  4E7L A;  1WEI A;  3F0Z A;  3OYL A;  1NKU A;  3S3M A; 
#chains in the Genus database with same CATH homology
 4OFE A;  4E9F A;  2YG8 A;  1KO9 A;  1MUN A;  1PU6 A;  3KTU A;  3G0Q A;  2I5W A;  4YOQ A;  1WEG A;  1EBM A;  3IHO A;  1LWW A;  2NOF A;  3CVS A;  1LMZ A;  5KN8 A;  3FSP A;  2NOB A;  4EJZ A;  4YPR A;  4EA5 A;  1ORP A;  3OH6 A;  3OH9 A;  1KG5 A;  2XHI A;  1WEF A;  1YQK A;  1KG6 A;  5CHZ A;  4PII A;  4DK9 A;  1N3C A;  3I0X A;  2NOZ A;  1KEA A;  4EW4 A;  1M3H A;  4OFH A;  1YQR A;  1MUD A;  1DIZ A;  2NOL A;  1PVS A;  4AI5 A;  3CW7 A;  1MPG A;  1KG3 A;  3FHG A;  4E9E A;  1PU7 A;  4HSB A;  1N3A A;  2H56 A;  1PU8 A;  2JG6 A;  2NOE A;  1N39 A;  1KG7 A;  4B24 A;  2JHN A;  1ORN A;  4EA4 A;  4B22 A;  3S6I A;  4EW0 A;  2NOI A;  5KN9 A;  1NGN A;  1P59 A;  4B23 A;  3I0W A;  1P7M A;  3CWA A;  3N0U A;  3D4V A;  1KG4 A;  3CVT A;  1RRS A;  1XQP A;  1KQJ A;  2JHJ A;  1XG7 A;  3KNT A;  3CWS A;  3OGD A;  4UNF A;  3FHF A;  1XQO A;  4E9G A;  2OFK A;  5DPK A;  2NOH A;  4YPH A;  4B21 A;  1HU0 A;  3CWT A;  2YG9 A;  4UOB A;  1YQM A;  4E9H A;  1VRL A;  3N5N X;  1LWY A;  3IH7 A;  4AI4 A;  3F10 A;  1KG2 A;  4OFA A;  3CWU A;  4EJY A;  1YQL A;  4AIA A;  4EVV A;  1LWV A;  1FN7 A;  5AN4 A;  1MUY A;  1RRQ A;  1M3Q A;  2ABK A;  1WEI A;  3F0Z A;  2OFI A;  1NKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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