5KN8A

Muty n-terminal domain in complex with undamaged dna
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
222
structure length
222
Chain Sequence
FPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
pubmed doi rcsb
molecule keywords Adenine DNA glycosylase
molecule tags Hydrolase/dna
source organism Geobacillus stearothermophilus
total genus 87
structure length 222
sequence length 222
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2016-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5kn8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 5kn8A01
5CHZA 1PU8A 1PU6A 1ORPA 1PVSA 1PU7A 4OFEA 1KG4A 4DK9A 2NOZA 4YPHA 1ORNA 4UNFA 3KNTA 1WEFA 5KN8A 4B22A 5DPKA 3N0UA 4EVVA 4AI5A 2ABKA 1WEGA 1DIZA 3KTUA 1FN7A 2XHIA 3S6IA 1RRSA 3CW7A 1XQPA 4EJYA 2NOFA 2YG9A 3OGDA 1WEIA 4YOQA 1NGNA 1MUDA 4B24A 1P59A 1YQRA 4E9GA 2H56A 4EW4A 1LWWA 4YPRA 1KG7A 3CWSA 2JG6A 4E9FA 3N5NX 1KG2A 1MPGA 3F10A 2I5WA 2NOEA 3FHGA 2JHNA 1KG6A 2YG8A 4AIAA 1M3QA 1MUNA 3OH6A 1HU0A 1NKUA 2NOIA 3FSPA 4EA5A 2OFIA 1KQJA 1N3AA 1YQKA 1M3HA 1KEAA 2JHJA 3FHFA 3F0ZA 1YQMA 1KG5A 4EA4A 1EBMA 4E9HA 1LWVA 4UOBA 3D4VA 1N3CA 4OFHA 2NOBA 2NOHA 1KO9A 5AN4A 1XQOA 4PIIA 1LMZA 1N39A 3G0QA 3IHOA 3CWTA 4AI4A 4EJZA 5KN9A 3CWUA 3CWAA 3IH7A 3I0XA 4EW0A 4HSBA 1MUYA 1LWYA 4E9EA 3I0WA 3OH9A 1VRLA 2NOLA 3CVTA 2OFKA 3CVSA 1KG3A 4B21A 4B23A 4OFAA 1YQLA 1XG7A 1P7MA 1RRQA
chains in the Genus database with same CATH superfamily
5CHZA 1PU8A 1PU6A 1ORPA 4E7HA 3OYHA 1PVSA 1PU7A 4OFEA 1KG4A 4E7LA 4DK9A 2NOZA 4YPHA 1RRQA 1ORNA 4UNFA 3KNTA 4ZTFA 1WEFA 5KN8A 4B22A 5DPKA 3N0UA 4EVVA 3L2UA 3OYMA 3OS2A 4AI5A 2ABKA 3OYFA 1WEGA 3OYIA 1DIZA 3KTUA 4E7KA 1FN7A 2XHIA 3S6IA 1RRSA 4BDZA 3CW7A 1XQPA 3OYDA 4EJYA 2NOFA 2YG9A 3OGDA 4E7IA 3OS1A 1WEIA 4YOQA 1NGNA 3S3MA 3LCNA 1MUDA 4B24A 3S3OA 3OYGA 1YQRA 1P59A 4E9GA 2H56A 4EW4A 1LWWA 4YPRA 1KG7A 3OYNA 3OS0A 4BE0A 3CWSA 2JG6A 4E7JA 4E9FA 3N5NX 4BE1A 1KG2A 1MPGA 3F10A 2I5WA 2NOEA 3FHGA 2W04A 2JHNA 1KG6A 2YG8A 4AIAA 3OYCA 1M3QA 1MUNA 3OH6A 1HU0A 4IKFA 1NKUA 2NOIA 3OYLA 5FRNA 3FSPA 4EA5A 3OYAA 1KQJA 2OFIA 1N3AA 2V75A 1YQKA 1M3HA 3OYEA 1KEAA 2JHJA 3FHFA 3F0ZA 3L2WA 1YQMA 1KG5A 4EA4A 1EBMA 4E9HA 3L2QA 3OYJA 1LWVA 4UOBA 3D4VA 4BDYA 2W03A 1N3CA 5FRMA 4OFHA 3NNQA 3R2XC 2NOBA 2NOHA 1KO9A 5AN4A 1XQOA 4PIIA 1LMZA 1N39A 3G0QA 3VW4A 3IHOA 3CWTA 4AI4A 3OY9A 4ZTJA 4EJZA 5KN9A 3CWUA 3S3NA 4NZGA 3CWAA 4BE2A 3OYKA 3IH7A 3I0XA 4EW0A 4HSBA 1MUYA 2JPSA 1LWYA 4E9EA 3I0WA 3OH9A 5FROA 1VRLA 3OYBA 3L2RA 2NOLA 3CVTA 4BACA 2OFKA 3CVSA 1KG3A 4B21A 4B23A 4OFAA 1YQLA 1XG7A 1U84A 1P7MA 3L2VA
chains in the Genus database with same CATH topology
5CHZA 1PU8A 1PU6A 1ORPA 1PVSA 1PU7A 4OFEA 1KG4A 4DK9A 2NOZA 4YPHA 1ORNA 4UNFA 3KNTA 1WEFA 5KN8A 4B22A 5DPKA 3N0UA 4EVVA 4AI5A 2ABKA 1WEGA 1DIZA 3KTUA 1FN7A 2XHIA 3S6IA 1RRSA 3CW7A 1XQPA 4EJYA 2NOFA 2YG9A 3OGDA 1WEIA 4YOQA 1NGNA 1MUDA 4B24A 1P59A 1YQRA 4E9GA 2H56A 4EW4A 1LWWA 4YPRA 1KG7A 3CWSA 2JG6A 4E9FA 3N5NX 1KG2A 1MPGA 3F10A 2I5WA 2NOEA 3FHGA 2JHNA 1KG6A 2YG8A 4AIAA 1M3QA 1MUNA 3OH6A 1HU0A 1NKUA 2NOIA 3FSPA 4EA5A 2OFIA 1KQJA 1N3AA 1YQKA 1M3HA 1KEAA 2JHJA 3FHFA 3F0ZA 1YQMA 1KG5A 4EA4A 1EBMA 4E9HA 1LWVA 4UOBA 3D4VA 1N3CA 4OFHA 2NOBA 2NOHA 1KO9A 5AN4A 1XQOA 4PIIA 1LMZA 1N39A 3G0QA 3IHOA 3CWTA 4AI4A 4EJZA 5KN9A 3CWUA 3CWAA 3IH7A 3I0XA 4EW0A 4HSBA 1MUYA 1LWYA 4E9EA 3I0WA 3OH9A 1VRLA 2NOLA 3CVTA 2OFKA 3CVSA 1KG3A 4B21A 4B23A 4OFAA 1YQLA 1XG7A 1P7MA 1RRQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CHZ A;  1PU8 A;  1PU6 A;  1ORP A;  1PVS A;  1PU7 A;  4OFE A;  1KG4 A;  4DK9 A;  2NOZ A;  4YPH A;  1ORN A;  4UNF A;  3KNT A;  1WEF A;  5KN8 A;  4B22 A;  5DPK A;  3N0U A;  4EVV A;  4AI5 A;  2ABK A;  1WEG A;  1DIZ A;  3KTU A;  1FN7 A;  2XHI A;  3S6I A;  1RRS A;  3CW7 A;  1XQP A;  4EJY A;  2NOF A;  2YG9 A;  3OGD A;  1WEI A;  4YOQ A;  1NGN A;  1MUD A;  4B24 A;  1P59 A;  1YQR A;  4E9G A;  2H56 A;  4EW4 A;  1LWW A;  4YPR A;  1KG7 A;  3CWS A;  2JG6 A;  4E9F A;  3N5N X;  1KG2 A;  1MPG A;  3F10 A;  2I5W A;  2NOE A;  3FHG A;  2JHN A;  1KG6 A;  2YG8 A;  4AIA A;  1M3Q A;  1MUN A;  3OH6 A;  1HU0 A;  1NKU A;  2NOI A;  3FSP A;  4EA5 A;  2OFI A;  1KQJ A;  1N3A A;  1YQK A;  1M3H A;  1KEA A;  2JHJ A;  3FHF A;  3F0Z A;  1YQM A;  1KG5 A;  4EA4 A;  1EBM A;  4E9H A;  1LWV A;  4UOB A;  3D4V A;  1N3C A;  4OFH A;  2NOB A;  2NOH A;  1KO9 A;  5AN4 A;  1XQO A;  4PII A;  1LMZ A;  1N39 A;  3G0Q A;  3IHO A;  3CWT A;  4AI4 A;  4EJZ A;  5KN9 A;  3CWU A;  3CWA A;  3IH7 A;  3I0X A;  4EW0 A;  4HSB A;  1MUY A;  1LWY A;  4E9E A;  3I0W A;  3OH9 A;  1VRL A;  2NOL A;  3CVT A;  2OFK A;  3CVS A;  1KG3 A;  4B21 A;  4B23 A;  4OFA A;  1YQL A;  1XG7 A;  1P7M A;  1RRQ A; 
#chains in the Genus database with same CATH topology
 5CHZ A;  1PU8 A;  1PU6 A;  1ORP A;  4E7H A;  3OYH A;  1PVS A;  1PU7 A;  4OFE A;  1KG4 A;  4E7L A;  4DK9 A;  2NOZ A;  4YPH A;  1RRQ A;  1ORN A;  4UNF A;  3KNT A;  4ZTF A;  1WEF A;  5KN8 A;  4B22 A;  5DPK A;  3N0U A;  4EVV A;  3L2U A;  3OYM A;  3OS2 A;  4AI5 A;  2ABK A;  3OYF A;  1WEG A;  3OYI A;  1DIZ A;  3KTU A;  4E7K A;  1FN7 A;  2XHI A;  3S6I A;  1RRS A;  4BDZ A;  3CW7 A;  1XQP A;  3OYD A;  4EJY A;  2NOF A;  2YG9 A;  3OGD A;  4E7I A;  3OS1 A;  1WEI A;  4YOQ A;  1NGN A;  3S3M A;  3LCN A;  1MUD A;  4B24 A;  3S3O A;  3OYG A;  1YQR A;  1P59 A;  4E9G A;  2H56 A;  4EW4 A;  1LWW A;  4YPR A;  1KG7 A;  3OYN A;  3OS0 A;  4BE0 A;  3CWS A;  2JG6 A;  4E7J A;  4E9F A;  3N5N X;  4BE1 A;  1KG2 A;  1MPG A;  3F10 A;  2I5W A;  2NOE A;  3FHG A;  2W04 A;  2JHN A;  1KG6 A;  2YG8 A;  4AIA A;  3OYC A;  1M3Q A;  1MUN A;  3OH6 A;  1HU0 A;  4IKF A;  1NKU A;  2NOI A;  3OYL A;  5FRN A;  3FSP A;  4EA5 A;  3OYA A;  1KQJ A;  2OFI A;  1N3A A;  2V75 A;  1YQK A;  1M3H A;  3OYE A;  1KEA A;  2JHJ A;  3FHF A;  3F0Z A;  3L2W A;  1YQM A;  1KG5 A;  4EA4 A;  1EBM A;  4E9H A;  3L2Q A;  3OYJ A;  1LWV A;  4UOB A;  3D4V A;  4BDY A;  2W03 A;  1N3C A;  5FRM A;  4OFH A;  3NNQ A;  3R2X C;  2NOB A;  2NOH A;  1KO9 A;  5AN4 A;  1XQO A;  4PII A;  1LMZ A;  1N39 A;  3G0Q A;  3VW4 A;  3IHO A;  3CWT A;  4AI4 A;  3OY9 A;  4ZTJ A;  4EJZ A;  5KN9 A;  3CWU A;  3S3N A;  4NZG A;  3CWA A;  4BE2 A;  3OYK A;  3IH7 A;  3I0X A;  4EW0 A;  4HSB A;  1MUY A;  2JPS A;  1LWY A;  4E9E A;  3I0W A;  3OH9 A;  5FRO A;  1VRL A;  3OYB A;  3L2R A;  2NOL A;  3CVT A;  4BAC A;  2OFK A;  3CVS A;  1KG3 A;  4B21 A;  4B23 A;  4OFA A;  1YQL A;  1XG7 A;  1U84 A;  1P7M A;  3L2V A; 
#chains in the Genus database with same CATH homology
 5CHZ A;  1PU8 A;  1PU6 A;  1ORP A;  1PVS A;  1PU7 A;  4OFE A;  1KG4 A;  4DK9 A;  2NOZ A;  4YPH A;  1ORN A;  4UNF A;  3KNT A;  1WEF A;  5KN8 A;  4B22 A;  5DPK A;  3N0U A;  4EVV A;  4AI5 A;  2ABK A;  1WEG A;  1DIZ A;  3KTU A;  1FN7 A;  2XHI A;  3S6I A;  1RRS A;  3CW7 A;  1XQP A;  4EJY A;  2NOF A;  2YG9 A;  3OGD A;  1WEI A;  4YOQ A;  1NGN A;  1MUD A;  4B24 A;  1P59 A;  1YQR A;  4E9G A;  2H56 A;  4EW4 A;  1LWW A;  4YPR A;  1KG7 A;  3CWS A;  2JG6 A;  4E9F A;  3N5N X;  1KG2 A;  1MPG A;  3F10 A;  2I5W A;  2NOE A;  3FHG A;  2JHN A;  1KG6 A;  2YG8 A;  4AIA A;  1M3Q A;  1MUN A;  3OH6 A;  1HU0 A;  1NKU A;  2NOI A;  3FSP A;  4EA5 A;  2OFI A;  1KQJ A;  1N3A A;  1YQK A;  1M3H A;  1KEA A;  2JHJ A;  3FHF A;  3F0Z A;  1YQM A;  1KG5 A;  4EA4 A;  1EBM A;  4E9H A;  1LWV A;  4UOB A;  3D4V A;  1N3C A;  4OFH A;  2NOB A;  2NOH A;  1KO9 A;  5AN4 A;  1XQO A;  4PII A;  1LMZ A;  1N39 A;  3G0Q A;  3IHO A;  3CWT A;  4AI4 A;  4EJZ A;  5KN9 A;  3CWU A;  3CWA A;  3IH7 A;  3I0X A;  4EW0 A;  4HSB A;  1MUY A;  1LWY A;  4E9E A;  3I0W A;  3OH9 A;  1VRL A;  2NOL A;  3CVT A;  2OFK A;  3CVS A;  1KG3 A;  4B21 A;  4B23 A;  4OFA A;  1YQL A;  1XG7 A;  1P7M A;  1RRQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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