5KP7B

Crystal structure of the curacin biosynthetic pathway hmg synthase in complex with holo donor-acp
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
79
structure length
79
Chain Sequence
MSKEQVLKIIKKYTREIAPELEDSPLEPTDSLKKLGIDSVNRAEIIMMVMEDLSLNIPRIELAGAKNIGELADLFAAKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Anatomy of the beta-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
pubmed doi rcsb
molecule keywords CurD
molecule tags Transferase
source organism Moorea producens 3l
total genus 25
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2016-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 5kp7B00
3GZMA 2DNWA 2L4BA 4BPFA 2GDWA 1T8KA 2MD9A 2LOLA 2GDYA 2KG6A 2AVAA 1NQ4A 1VKUA 5KP6B 2KWLA 5KP8B 4CA3A 3CE7A 2N6YA 5EJDA 2KG8A 2KGAA 3LMOA 2GDXA 2LL8A 2KG9A 2KOPA 4R0MA 2M5RA 2AFEA 2FVAA 3NY7B 2VSQA 4H2XC 2L22A 2PNGA 2AF8A 5HV8A 2FADA 1HQBA 2K93A 1L0HA 2KOSA 1L0IA 1DNYA 2FAEA 2AFDA 2KGDA 2LKIA 2MF4A 4H2WC 2EHSA 5HVCA 2JGPA 2L9FA 2X2BA 1F80D 2N50A 2FQ1A 2N6ZA 4NEOA 3RG2A 3EJBA 2L0QA 2JU2A 4MRTC 2N98A 2MVVA 2FACA 2KR5A 4DG9A 3GZLA 2XZ1C 2FQ0A 2LIUA 2MR8A 1HY8A 2K2QA 2CGQA 1OR5A 2KOOA 2LMLA 2LTEA 2FVFA 2QNWA 2K0YA 2N5IA 2EHTA 2KGCA 2K0XA 2KORA 5CZDB 2LIWA 2CNRA 2CQ8A 2MY5A 4H2YC 2JQ4A 5KP7B 2ROQA 2N5HA 4IZ6A 2FVEA 2KW2A 2FHSC 2K94A 2FQ2A 4BPGA 2MR7A 4PXHB 1X3OA 1KLPA 4HKGA 2KGEA 2CG5B 2K92A 1AF8A 2MVUA 3EJDA 1DV5A 2LPKA 4PWVB 4BPHA 2JU1A 1ACPA 3EJEA 2XZ0D 2KOQA
chains in the Genus database with same CATH superfamily
3I56P 2L4BA 2EIAA 1VQOP 1T8KA 2AVAA 1KQSO 3G6EP 2NO8A 1M74A 2KWLA 4XFYA 2N6YA 2Z46A 3H4EA 2LL8A 2DGYA 3MGEA 2FVAA 2OTLP 2M8NA 2VSQA 2L22A 2AF8A 1RO0A 2K93A 1AUMA 5HGOA 2VLQA 2KOSA 2FAEA 2BHVA 1M6NA 2PY8A 1VQ5P 1YJ9P 2GYKA 2Z45A 3HZQA 4COCA 1VQKP 2EHSA 3GKLC 2JGPA 2L9FA 1ZMBA 2X2BA 2N50A 2FQ1A 1D1DA 1W2BO 1Q81Q 3Q20A 3NTEA 3CC4P 3CMAP 1YHQP 1EOQA 1AYIA 2GZIA 4DG9A 3GZLA 2XZ1C 2VLNA 2LIUA 2PEIA 1YI2P 1VQ8P 1HY8A 2K2QA 5F2NA 4GR6A 5DCKA 2QEXP 5JPAA 2K0XA 5CZDB 2LF4A 2CQ8A 5KP7B 2KW2A 2FHSC 2K94A 3G71P 2FQ2A 4BPGA 4HKGA 1FR2A 2MVUA 1K73Q 4BPHA 1ACPA 4COPA 2DNWA 3CC7P 2GDYA 2KG6A 2K5XA 2XT1A 4CA3A 4QKOA 1YJNP 2M8PA 4XROA 2KG8A 1E6JP 2KG9A 2KOPA 5F2OA 2ONTA 1VQNP 3NY7B 1YIJP 4H2XC 3B5IA 2PNGA 4U0FA 2JAZA 5HV8A 5EW5E 1HQBA 2GZGA 1L0IA 1DNYA 2Z44A 1VQPP 2AFDA 2XXMA 2KGDA 3CCJP 2MF4A 3CCQP 4H2WC 1M6EX 3WBHA 1ZNVA 3G29A 1GXGA 3DS2A 5HVCA 1Q7YQ 3G4SP 1F80D 2JYLA 4NEOA 3EJBA 3CXCO 4U0BA 3CD6P 3CCLP 3CCRP 2N98A 2MVVA 2KR5A 2CWOA 3G1GA 1VQMP 1EMVA 3U43A 2P9XA 2JYGA 2KOOA 2LMLA 2LTEA 1NJIQ 1UJZA 2QNWA 2K0YA 3CCVP 3G26A 2EHTA 2KORA 2LIWA 2CNRA 4QNBA 3H0DA 4IPYA 1QVGO 2MR7A 3GJNA 3VRLC 1AF8A 3HYBA 4U0EA 4PH1A 1EIAA 1S72P 2XZ0D 3GZMA 5HGLA 4BPFA 2PEKA 3P05A 2GDWA 2MD9A 1VQ9P 2OARA 4GR2A 2PEMA 2JB0A 2KGAA 1IMPA 3DPHA 4R0MA 1N8RQ 5HGNA 2AFEA 1VQLP 4U0AA 2WPTA 2XV6A 2FADA 4M0IA 1CEIA 1BXIA 2KODA 3G1IA 2K0DX 4XRQA 4U0DA 4XFXA 3M1MA 2LKIA 2VLPA 3CCSP 2GZFA 3RG2A 2N6ZA 2L0QA 1QVFO 1K9MQ 7CEIA 4MRTC 2FQ0A 2OTJP 5BS2A 1QRJA 3B4QA 2CGQA 2GZEA 3DS5A 2FVFA 1RNIA 2PEOA 3CPWO 2KGCA 3I55P 2M8LA 1RO2A 1UNKA 3CMEP 4F37A 1M90Q 3G28A 1YITP 2ERHA 4H2YC 2N5HA 1Z6MA 2FVEA 3DS1A 2PENA 1X3OA 2QA4P 2KGEA 3RG6C 4WYMA 3G21A 1DV5A 2LPKA 1VQ6P 2GZJA 2KOQA 1E0HA 3DS4A 3OW2O 1Q86Q 2LOLA 1NQ4A 1VKUA 1IMQA 4U0CA 5KP6B 1GXHA 5KP8B 5HGMA 3CE7A 3DTJA 5EJDA 3LMOA 4XFZA 2GDXA 2PEQA 4PH0A 3CCMP 1KC8Q 1VHNA 2M5RA 1BAJA 3CC2P 1VQ7P 5BS1A 1L0HA 1K30A 2VLOA 2PEJA 2EFJA 1YJWP 2L6EA 2E1MA 4UHPB 1Q82Q 3E2DA 1MZ8A 2JU2A 5I4TG 3CCUP 5F2KA 1M1KQ 1K8AQ 2FACA 1KD1Q 2MR8A 3H47A 1GPJA 1IUQA 3DS3A 1OR5A 1A8OA 2N5IA 2EG5A 1JJ2O 2JO0A 3CCEP 2MY5A 2JQ4A 2ROQA 4IZ6A 4PXHB 1KLPA 3LRYA 2BUOA 2CG5B 2K92A 3DS0A 1A43A 2JBGA 3G0VA 1VQ4P 3EJDA 4PWVB 2JU1A 3EJEA
chains in the Genus database with same CATH topology
3GZMA 2DNWA 2L4BA 4BPFA 2GDWA 1T8KA 2MD9A 2LOLA 2GDYA 2KG6A 2AVAA 1NQ4A 1VKUA 5KP6B 2KWLA 5KP8B 4CA3A 3CE7A 2N6YA 5EJDA 2KG8A 2KGAA 3LMOA 2GDXA 2LL8A 2KG9A 2KOPA 4R0MA 2M5RA 2AFEA 2FVAA 3NY7B 2VSQA 4H2XC 2L22A 2PNGA 2AF8A 5HV8A 2FADA 1HQBA 2K93A 1L0HA 2KOSA 1L0IA 1DNYA 2FAEA 2AFDA 2KGDA 2LKIA 2MF4A 4H2WC 2EHSA 5HVCA 2JGPA 2L9FA 2X2BA 1F80D 2N50A 2FQ1A 2N6ZA 4NEOA 3RG2A 3EJBA 2L0QA 2JU2A 4MRTC 2N98A 2MVVA 2FACA 2KR5A 4DG9A 3GZLA 2XZ1C 2FQ0A 2LIUA 2MR8A 1HY8A 2K2QA 2CGQA 1OR5A 2KOOA 2LMLA 2LTEA 2FVFA 2QNWA 2K0YA 2N5IA 2EHTA 2KGCA 2K0XA 2KORA 5CZDB 2LIWA 2CNRA 2CQ8A 2MY5A 4H2YC 2JQ4A 5KP7B 2ROQA 2N5HA 4IZ6A 2FVEA 2KW2A 2FHSC 2K94A 2FQ2A 4BPGA 2MR7A 4PXHB 1X3OA 1KLPA 4HKGA 2KGEA 2CG5B 2K92A 1AF8A 2MVUA 3EJDA 1DV5A 2LPKA 4PWVB 4BPHA 2JU1A 1ACPA 3EJEA 2XZ0D 2KOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GZM A;  2DNW A;  2L4B A;  4BPF A;  2GDW A;  1T8K A;  2MD9 A;  2LOL A;  2GDY A;  2KG6 A;  2AVA A;  1NQ4 A;  1VKU A;  5KP6 B;  2KWL A;  5KP8 B;  4CA3 A;  3CE7 A;  2N6Y A;  5EJD A;  2KG8 A;  2KGA A;  3LMO A;  2GDX A;  2LL8 A;  2KG9 A;  2KOP A;  4R0M A;  2M5R A;  2AFE A;  2FVA A;  3NY7 B;  2VSQ A;  4H2X C;  2L22 A;  2PNG A;  2AF8 A;  5HV8 A;  2FAD A;  1HQB A;  2K93 A;  1L0H A;  2KOS A;  1L0I A;  1DNY A;  2FAE A;  2AFD A;  2KGD A;  2LKI A;  2MF4 A;  4H2W C;  2EHS A;  5HVC A;  2JGP A;  2L9F A;  2X2B A;  1F80 D;  2N50 A;  2FQ1 A;  2N6Z A;  4NEO A;  3RG2 A;  3EJB A;  2L0Q A;  2JU2 A;  4MRT C;  2N98 A;  2MVV A;  2FAC A;  2KR5 A;  4DG9 A;  3GZL A;  2XZ1 C;  2FQ0 A;  2LIU A;  2MR8 A;  1HY8 A;  2K2Q A;  2CGQ A;  1OR5 A;  2KOO A;  2LML A;  2LTE A;  2FVF A;  2QNW A;  2K0Y A;  2N5I A;  2EHT A;  2KGC A;  2K0X A;  2KOR A;  5CZD B;  2LIW A;  2CNR A;  2CQ8 A;  2MY5 A;  4H2Y C;  2JQ4 A;  5KP7 B;  2ROQ A;  2N5H A;  4IZ6 A;  2FVE A;  2KW2 A;  2FHS C;  2K94 A;  2FQ2 A;  4BPG A;  2MR7 A;  4PXH B;  1X3O A;  1KLP A;  4HKG A;  2KGE A;  2CG5 B;  2K92 A;  1AF8 A;  2MVU A;  3EJD A;  1DV5 A;  2LPK A;  4PWV B;  4BPH A;  2JU1 A;  1ACP A;  3EJE A;  2XZ0 D;  2KOQ A; 
#chains in the Genus database with same CATH topology
 3I56 P;  2L4B A;  2EIA A;  1VQO P;  1T8K A;  2AVA A;  1KQS O;  3G6E P;  2NO8 A;  1M74 A;  2KWL A;  4XFY A;  2N6Y A;  2Z46 A;  3H4E A;  2LL8 A;  2DGY A;  3MGE A;  2FVA A;  2OTL P;  2M8N A;  2VSQ A;  2L22 A;  2AF8 A;  1RO0 A;  2K93 A;  1AUM A;  5HGO A;  2VLQ A;  2KOS A;  2FAE A;  2BHV A;  1M6N A;  2PY8 A;  1VQ5 P;  1YJ9 P;  2GYK A;  2Z45 A;  3HZQ A;  4COC A;  1VQK P;  2EHS A;  3GKL C;  2JGP A;  2L9F A;  1ZMB A;  2X2B A;  2N50 A;  2FQ1 A;  1D1D A;  1W2B O;  1Q81 Q;  3Q20 A;  3NTE A;  3CC4 P;  3CMA P;  1YHQ P;  1EOQ A;  1AYI A;  2GZI A;  4DG9 A;  3GZL A;  2XZ1 C;  2VLN A;  2LIU A;  2PEI A;  1YI2 P;  1VQ8 P;  1HY8 A;  2K2Q A;  5F2N A;  4GR6 A;  5DCK A;  2QEX P;  5JPA A;  2K0X A;  5CZD B;  2LF4 A;  2CQ8 A;  5KP7 B;  2KW2 A;  2FHS C;  2K94 A;  3G71 P;  2FQ2 A;  4BPG A;  4HKG A;  1FR2 A;  2MVU A;  1K73 Q;  4BPH A;  1ACP A;  4COP A;  2DNW A;  3CC7 P;  2GDY A;  2KG6 A;  2K5X A;  2XT1 A;  4CA3 A;  4QKO A;  1YJN P;  2M8P A;  4XRO A;  2KG8 A;  1E6J P;  2KG9 A;  2KOP A;  5F2O A;  2ONT A;  1VQN P;  3NY7 B;  1YIJ P;  4H2X C;  3B5I A;  2PNG A;  4U0F A;  2JAZ A;  5HV8 A;  5EW5 E;  1HQB A;  2GZG A;  1L0I A;  1DNY A;  2Z44 A;  1VQP P;  2AFD A;  2XXM A;  2KGD A;  3CCJ P;  2MF4 A;  3CCQ P;  4H2W C;  1M6E X;  3WBH A;  1ZNV A;  3G29 A;  1GXG A;  3DS2 A;  5HVC A;  1Q7Y Q;  3G4S P;  1F80 D;  2JYL A;  4NEO A;  3EJB A;  3CXC O;  4U0B A;  3CD6 P;  3CCL P;  3CCR P;  2N98 A;  2MVV A;  2KR5 A;  2CWO A;  3G1G A;  1VQM P;  1EMV A;  3U43 A;  2P9X A;  2JYG A;  2KOO A;  2LML A;  2LTE A;  1NJI Q;  1UJZ A;  2QNW A;  2K0Y A;  3CCV P;  3G26 A;  2EHT A;  2KOR A;  2LIW A;  2CNR A;  4QNB A;  3H0D A;  4IPY A;  1QVG O;  2MR7 A;  3GJN A;  3VRL C;  1AF8 A;  3HYB A;  4U0E A;  4PH1 A;  1EIA A;  1S72 P;  2XZ0 D;  3GZM A;  5HGL A;  4BPF A;  2PEK A;  3P05 A;  2GDW A;  2MD9 A;  1VQ9 P;  2OAR A;  4GR2 A;  2PEM A;  2JB0 A;  2KGA A;  1IMP A;  3DPH A;  4R0M A;  1N8R Q;  5HGN A;  2AFE A;  1VQL P;  4U0A A;  2WPT A;  2XV6 A;  2FAD A;  4M0I A;  1CEI A;  1BXI A;  2KOD A;  3G1I A;  2K0D X;  4XRQ A;  4U0D A;  4XFX A;  3M1M A;  2LKI A;  2VLP A;  3CCS P;  2GZF A;  3RG2 A;  2N6Z A;  2L0Q A;  1QVF O;  1K9M Q;  7CEI A;  4MRT C;  2FQ0 A;  2OTJ P;  5BS2 A;  1QRJ A;  3B4Q A;  2CGQ A;  2GZE A;  3DS5 A;  2FVF A;  1RNI A;  2PEO A;  3CPW O;  2KGC A;  3I55 P;  2M8L A;  1RO2 A;  1UNK A;  3CME P;  4F37 A;  1M90 Q;  3G28 A;  1YIT P;  2ERH A;  4H2Y C;  2N5H A;  1Z6M A;  2FVE A;  3DS1 A;  2PEN A;  1X3O A;  2QA4 P;  2KGE A;  3RG6 C;  4WYM A;  3G21 A;  1DV5 A;  2LPK A;  1VQ6 P;  2GZJ A;  2KOQ A;  1E0H A;  3DS4 A;  3OW2 O;  1Q86 Q;  2LOL A;  1NQ4 A;  1VKU A;  1IMQ A;  4U0C A;  5KP6 B;  1GXH A;  5KP8 B;  5HGM A;  3CE7 A;  3DTJ A;  5EJD A;  3LMO A;  4XFZ A;  2GDX A;  2PEQ A;  4PH0 A;  3CCM P;  1KC8 Q;  1VHN A;  2M5R A;  1BAJ A;  3CC2 P;  1VQ7 P;  5BS1 A;  1L0H A;  1K30 A;  2VLO A;  2PEJ A;  2EFJ A;  1YJW P;  2L6E A;  2E1M A;  4UHP B;  1Q82 Q;  3E2D A;  1MZ8 A;  2JU2 A;  5I4T G;  3CCU P;  5F2K A;  1M1K Q;  1K8A Q;  2FAC A;  1KD1 Q;  2MR8 A;  3H47 A;  1GPJ A;  1IUQ A;  3DS3 A;  1OR5 A;  1A8O A;  2N5I A;  2EG5 A;  1JJ2 O;  2JO0 A;  3CCE P;  2MY5 A;  2JQ4 A;  2ROQ A;  4IZ6 A;  4PXH B;  1KLP A;  3LRY A;  2BUO A;  2CG5 B;  2K92 A;  3DS0 A;  1A43 A;  2JBG A;  3G0V A;  1VQ4 P;  3EJD A;  4PWV B;  2JU1 A;  3EJE A; 
#chains in the Genus database with same CATH homology
 3GZM A;  2DNW A;  2L4B A;  4BPF A;  2GDW A;  1T8K A;  2MD9 A;  2LOL A;  2GDY A;  2KG6 A;  2AVA A;  1NQ4 A;  1VKU A;  5KP6 B;  2KWL A;  5KP8 B;  4CA3 A;  3CE7 A;  2N6Y A;  5EJD A;  2KG8 A;  2KGA A;  3LMO A;  2GDX A;  2LL8 A;  2KG9 A;  2KOP A;  4R0M A;  2M5R A;  2AFE A;  2FVA A;  3NY7 B;  2VSQ A;  4H2X C;  2L22 A;  2PNG A;  2AF8 A;  5HV8 A;  2FAD A;  1HQB A;  2K93 A;  1L0H A;  2KOS A;  1L0I A;  1DNY A;  2FAE A;  2AFD A;  2KGD A;  2LKI A;  2MF4 A;  4H2W C;  2EHS A;  5HVC A;  2JGP A;  2L9F A;  2X2B A;  1F80 D;  2N50 A;  2FQ1 A;  2N6Z A;  4NEO A;  3RG2 A;  3EJB A;  2L0Q A;  2JU2 A;  4MRT C;  2N98 A;  2MVV A;  2FAC A;  2KR5 A;  4DG9 A;  3GZL A;  2XZ1 C;  2FQ0 A;  2LIU A;  2MR8 A;  1HY8 A;  2K2Q A;  2CGQ A;  1OR5 A;  2KOO A;  2LML A;  2LTE A;  2FVF A;  2QNW A;  2K0Y A;  2N5I A;  2EHT A;  2KGC A;  2K0X A;  2KOR A;  5CZD B;  2LIW A;  2CNR A;  2CQ8 A;  2MY5 A;  4H2Y C;  2JQ4 A;  5KP7 B;  2ROQ A;  2N5H A;  4IZ6 A;  2FVE A;  2KW2 A;  2FHS C;  2K94 A;  2FQ2 A;  4BPG A;  2MR7 A;  4PXH B;  1X3O A;  1KLP A;  4HKG A;  2KGE A;  2CG5 B;  2K92 A;  1AF8 A;  2MVU A;  3EJD A;  1DV5 A;  2LPK A;  4PWV B;  4BPH A;  2JU1 A;  1ACP A;  3EJE A;  2XZ0 D;  2KOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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