5L0KA

Crystal structure of autotaxin and compound pf-8380
Total Genus 229
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
229
sequence length
807
structure length
777
Chain Sequence
ATSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSIANSKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDDTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCASSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 229
structure length 777
sequence length 807
chains with identical sequence B
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2016-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 5l0kA04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5l0kA03
2ANHA 1QL0A 2XH3A 1KH5A 1G8TA 3M8WA 2W5XA 4N7TA 2W5WA 4KJDA 2IUCB 5KXAA 1ANJA 1KH9A 1ALHA 4GTZA 3TX0A 4UOOA 1ZEDA 1AUKA 1KH4A 4B56A 4FDJA 5DLVA 3NKOA 5EGEA 3MK2A 5K4PA 4NWJA 5EGHA 3DYCA 4LR9A 1ZM8A 4ZG9A 1KHKA 1ZEBA 3BDFA 3IGYB 3Q3QA 1ALKA 3WAVA 3NVLA 3UN5A 2G9YA 1B8JA 1EI6A 2GA3A 5GKPA 1SHNA 1ANIA 2W5TA 1URAA 3IGZB 3A52A 1AJBA 2GLQA 2IFYA 3BDHA 3SZYA 1ED9A 1E2SP 3BDGB 4LRAA 4ZG7A 1N2LA 1O98A 4KJGA 4UORA 1E33P 3M7VA 1ELXA 1N2KA 2X98A 1AJAA 5LRMA 4LQYA 4LR8A 4ZG6A 4A1NA 4LRBA 4KAVA 5LIAA 1KHNA 3M8ZA 5IJSA 5LQQA 2QZUA 3KD8A 4KM4A 3UN3A 4CXKA 1KHJA 4QAXA 3TWZA 1EW9A 1Y7AA 2IUCA 3WBHA 4ZGAA 1ELZA 1EW8A 1AJDA 4QN0A 4MIVA 3WAYA 1ALIA 4UOPA 4MHXA 3OT9A 1KH7A 4GTWA 3NKMA 5DLWA 4LRFA 3MK1A 4UPLA 1EJJA 3NKRA 1QAEA 2W5VA 1EQJA 4FDIA 1HDHA 2XGRA 2ZKTA 1P49A 4LRDA 4MY4A 5AJ9A 5IJQA 5L0EA 2GSUA 2XR9A 2W8SA 1ZEFA 4CXUA 4CYSA 5TJ3A 2W5SA 4UPHA 5GOVA 2W5QA 3T00A 4QH0A 4LREA 3SZZA 3UN2A 3NKQA 3LXQA 3MK0A 1HJKA 1EW2A 3ISMA 4GTYA 2D1GA 4YR1A 3TG0A 4LR2A 1SMNA 3WAWA 2RH6A 3NKPA 3S5BA 4E3YA 1FSUA 4CXSA 1K7HA 4GTXA 1KHLA 1HQAA 1E3CP 2W5RA 5HRTA 3IDDA 5C66A 5DLTA 1SHQA 1Y6VA 3DPCA 4LR7A 4KAYA 2W8DA 4LRCA 3ED4A 3WAXA 2VQRA 3UNYA 5L0KA 4TN0A 3E2DA 3NKNA 1ED8A 3B5QA 3M8YA 4QGOA 2O3BA 1URBA 4UPIA 1O99A 3UO0A 2XRGA 3CMRA 3OWVA 1E1ZP 5L0BA 3BDGA 4CYRA 1ALJA 4NWXA 5INHA 2GSOA 1ELYA 2GSNA 4UPKA 3T02A 5GRRA 5GKCA 3T01A 5LRNA 1AJCA
chains in the Genus database with same CATH superfamily
2ANHA 1QL0A 2XH3A 1KH5A 1G8TA 3M8WA 2W5XA 4N7TA 2W5WA 4KJDA 2IUCB 5KXAA 1ANJA 1KH9A 1ALHA 4GTZA 3TX0A 4UOOA 1ZEDA 1AUKA 1KH4A 4B56A 4FDJA 5DLVA 3NKOA 5EGEA 3MK2A 5K4PA 4NWJA 5EGHA 3DYCA 4LR9A 1ZM8A 4ZG9A 1KHKA 1ZEBA 3BDFA 3IGYB 3Q3QA 1ALKA 3WAVA 3NVLA 3UN5A 2G9YA 1B8JA 1EI6A 2GA3A 5GKPA 1SHNA 1ANIA 2W5TA 1URAA 3IGZB 3A52A 1AJBA 2GLQA 2IFYA 3BDHA 3SZYA 1ED9A 1E2SP 3BDGB 4LRAA 4ZG7A 1N2LA 1O98A 4KJGA 4UORA 1E33P 3M7VA 1ELXA 1N2KA 2X98A 1AJAA 5LRMA 4LQYA 4LR8A 4ZG6A 4A1NA 4LRBA 4KAVA 5LIAA 1KHNA 3M8ZA 5IJSA 5LQQA 2QZUA 3KD8A 4KM4A 3UN3A 4CXKA 1KHJA 4QAXA 3TWZA 1EW9A 1Y7AA 2IUCA 3WBHA 4ZGAA 1ELZA 1EW8A 1AJDA 4QN0A 4MIVA 3WAYA 1ALIA 4UOPA 4MHXA 3OT9A 1KH7A 4GTWA 3NKMA 5DLWA 4LRFA 3MK1A 4UPLA 1EJJA 3NKRA 1QAEA 2W5VA 1EQJA 4FDIA 1HDHA 2XGRA 2ZKTA 1P49A 4LRDA 4MY4A 5AJ9A 5IJQA 5L0EA 2GSUA 2XR9A 2W8SA 1ZEFA 4CXUA 4CYSA 5TJ3A 2W5SA 4UPHA 5GOVA 2W5QA 3T00A 4QH0A 4LREA 3SZZA 3UN2A 3NKQA 3LXQA 3MK0A 1HJKA 1EW2A 3ISMA 4GTYA 2D1GA 4YR1A 3TG0A 4LR2A 1SMNA 3WAWA 2RH6A 3NKPA 3S5BA 4E3YA 1FSUA 4CXSA 1K7HA 4GTXA 1KHLA 1HQAA 1E3CP 2W5RA 5HRTA 3IDDA 5C66A 5DLTA 1SHQA 1Y6VA 3DPCA 4LR7A 4KAYA 2W8DA 4LRCA 3ED4A 3WAXA 2VQRA 3UNYA 5L0KA 4TN0A 3E2DA 3NKNA 1ED8A 3B5QA 3M8YA 4QGOA 2O3BA 1URBA 4UPIA 1O99A 3UO0A 2XRGA 3CMRA 3OWVA 1E1ZP 5L0BA 3BDGA 4CYRA 1ALJA 4NWXA 5INHA 2GSOA 1ELYA 2GSNA 4UPKA 3T02A 5GRRA 5GKCA 3T01A 5LRNA 1AJCA
chains in the Genus database with same CATH topology
2ANHA 1QL0A 2XH3A 1KH5A 1G8TA 3M8WA 2W5XA 4N7TA 2W5WA 4KJDA 2IUCB 5KXAA 1ANJA 1KH9A 1ALHA 4GTZA 3TX0A 4UOOA 1ZEDA 1AUKA 1KH4A 4B56A 4FDJA 5DLVA 3NKOA 5EGEA 3MK2A 5K4PA 4NWJA 5EGHA 3DYCA 4LR9A 1ZM8A 4ZG9A 1KHKA 1ZEBA 3BDFA 3IGYB 3Q3QA 1ALKA 3WAVA 3NVLA 3UN5A 2G9YA 1B8JA 1EI6A 2GA3A 5GKPA 1SHNA 1ANIA 2W5TA 1URAA 3IGZB 3A52A 1AJBA 2GLQA 2IFYA 3BDHA 3SZYA 1ED9A 1E2SP 3BDGB 4LRAA 4ZG7A 1N2LA 1O98A 4KJGA 4UORA 1E33P 3M7VA 1ELXA 1N2KA 2X98A 1AJAA 5LRMA 4LQYA 4LR8A 4ZG6A 4A1NA 4LRBA 4KAVA 5LIAA 1KHNA 3M8ZA 5IJSA 5LQQA 2QZUA 3KD8A 4KM4A 3UN3A 4CXKA 1KHJA 4QAXA 3TWZA 1EW9A 1Y7AA 2IUCA 3WBHA 4ZGAA 1ELZA 1EW8A 1AJDA 4QN0A 4MIVA 3WAYA 1ALIA 4UOPA 4MHXA 3OT9A 1KH7A 4GTWA 3NKMA 5DLWA 4LRFA 3MK1A 4UPLA 1EJJA 3NKRA 1QAEA 2W5VA 1EQJA 4FDIA 1HDHA 2XGRA 2ZKTA 1P49A 4LRDA 4MY4A 5AJ9A 5IJQA 5L0EA 2GSUA 2XR9A 2W8SA 1ZEFA 4CXUA 4CYSA 5TJ3A 2W5SA 4UPHA 5GOVA 2W5QA 3T00A 4QH0A 4LREA 3SZZA 3UN2A 3NKQA 3LXQA 3MK0A 1HJKA 1EW2A 3ISMA 4GTYA 2D1GA 4YR1A 3TG0A 4LR2A 1SMNA 3WAWA 2RH6A 3NKPA 3S5BA 4E3YA 1FSUA 4CXSA 1K7HA 4GTXA 1KHLA 1HQAA 1E3CP 2W5RA 5HRTA 3IDDA 5C66A 5DLTA 1SHQA 1Y6VA 3DPCA 4LR7A 4KAYA 2W8DA 4LRCA 3ED4A 3WAXA 2VQRA 3UNYA 5L0KA 4TN0A 3E2DA 3NKNA 1ED8A 3B5QA 3M8YA 4QGOA 2O3BA 1URBA 4UPIA 1O99A 3UO0A 2XRGA 3CMRA 3OWVA 1E1ZP 5L0BA 3BDGA 4CYRA 1ALJA 4NWXA 5INHA 2GSOA 1ELYA 2GSNA 4UPKA 3T02A 5GRRA 5GKCA 3T01A 5LRNA 1AJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ANH A;  1QL0 A;  2XH3 A;  1KH5 A;  1G8T A;  3M8W A;  2W5X A;  4N7T A;  2W5W A;  4KJD A;  2IUC B;  5KXA A;  1ANJ A;  1KH9 A;  1ALH A;  4GTZ A;  3TX0 A;  4UOO A;  1ZED A;  1AUK A;  1KH4 A;  4B56 A;  4FDJ A;  5DLV A;  3NKO A;  5EGE A;  3MK2 A;  5K4P A;  4NWJ A;  5EGH A;  3DYC A;  4LR9 A;  1ZM8 A;  4ZG9 A;  1KHK A;  1ZEB A;  3BDF A;  3IGY B;  3Q3Q A;  1ALK A;  3WAV A;  3NVL A;  3UN5 A;  2G9Y A;  1B8J A;  1EI6 A;  2GA3 A;  5GKP A;  1SHN A;  1ANI A;  2W5T A;  1URA A;  3IGZ B;  3A52 A;  1AJB A;  2GLQ A;  2IFY A;  3BDH A;  3SZY A;  1ED9 A;  1E2S P;  3BDG B;  4LRA A;  4ZG7 A;  1N2L A;  1O98 A;  4KJG A;  4UOR A;  1E33 P;  3M7V A;  1ELX A;  1N2K A;  2X98 A;  1AJA A;  5LRM A;  4LQY A;  4LR8 A;  4ZG6 A;  4A1N A;  4LRB A;  4KAV A;  5LIA A;  1KHN A;  3M8Z A;  5IJS A;  5LQQ A;  2QZU A;  3KD8 A;  4KM4 A;  3UN3 A;  4CXK A;  1KHJ A;  4QAX A;  3TWZ A;  1EW9 A;  1Y7A A;  2IUC A;  3WBH A;  4ZGA A;  1ELZ A;  1EW8 A;  1AJD A;  4QN0 A;  4MIV A;  3WAY A;  1ALI A;  4UOP A;  4MHX A;  3OT9 A;  1KH7 A;  4GTW A;  3NKM A;  5DLW A;  4LRF A;  3MK1 A;  4UPL A;  1EJJ A;  3NKR A;  1QAE A;  2W5V A;  1EQJ A;  4FDI A;  1HDH A;  2XGR A;  2ZKT A;  1P49 A;  4LRD A;  4MY4 A;  5AJ9 A;  5IJQ A;  5L0E A;  2GSU A;  2XR9 A;  2W8S A;  1ZEF A;  4CXU A;  4CYS A;  5TJ3 A;  2W5S A;  4UPH A;  5GOV A;  2W5Q A;  3T00 A;  4QH0 A;  4LRE A;  3SZZ A;  3UN2 A;  3NKQ A;  3LXQ A;  3MK0 A;  1HJK A;  1EW2 A;  3ISM A;  4GTY A;  2D1G A;  4YR1 A;  3TG0 A;  4LR2 A;  1SMN A;  3WAW A;  2RH6 A;  3NKP A;  3S5B A;  4E3Y A;  1FSU A;  4CXS A;  1K7H A;  4GTX A;  1KHL A;  1HQA A;  1E3C P;  2W5R A;  5HRT A;  3IDD A;  5C66 A;  5DLT A;  1SHQ A;  1Y6V A;  3DPC A;  4LR7 A;  4KAY A;  2W8D A;  4LRC A;  3ED4 A;  3WAX A;  2VQR A;  3UNY A;  5L0K A;  4TN0 A;  3E2D A;  3NKN A;  1ED8 A;  3B5Q A;  3M8Y A;  4QGO A;  2O3B A;  1URB A;  4UPI A;  1O99 A;  3UO0 A;  2XRG A;  3CMR A;  3OWV A;  1E1Z P;  5L0B A;  3BDG A;  4CYR A;  1ALJ A;  4NWX A;  5INH A;  2GSO A;  1ELY A;  2GSN A;  4UPK A;  3T02 A;  5GRR A;  5GKC A;  3T01 A;  5LRN A;  1AJC A; 
#chains in the Genus database with same CATH topology
 2ANH A;  1QL0 A;  2XH3 A;  1KH5 A;  1G8T A;  3M8W A;  2W5X A;  4N7T A;  2W5W A;  4KJD A;  2IUC B;  5KXA A;  1ANJ A;  1KH9 A;  1ALH A;  4GTZ A;  3TX0 A;  4UOO A;  1ZED A;  1AUK A;  1KH4 A;  4B56 A;  4FDJ A;  5DLV A;  3NKO A;  5EGE A;  3MK2 A;  5K4P A;  4NWJ A;  5EGH A;  3DYC A;  4LR9 A;  1ZM8 A;  4ZG9 A;  1KHK A;  1ZEB A;  3BDF A;  3IGY B;  3Q3Q A;  1ALK A;  3WAV A;  3NVL A;  3UN5 A;  2G9Y A;  1B8J A;  1EI6 A;  2GA3 A;  5GKP A;  1SHN A;  1ANI A;  2W5T A;  1URA A;  3IGZ B;  3A52 A;  1AJB A;  2GLQ A;  2IFY A;  3BDH A;  3SZY A;  1ED9 A;  1E2S P;  3BDG B;  4LRA A;  4ZG7 A;  1N2L A;  1O98 A;  4KJG A;  4UOR A;  1E33 P;  3M7V A;  1ELX A;  1N2K A;  2X98 A;  1AJA A;  5LRM A;  4LQY A;  4LR8 A;  4ZG6 A;  4A1N A;  4LRB A;  4KAV A;  5LIA A;  1KHN A;  3M8Z A;  5IJS A;  5LQQ A;  2QZU A;  3KD8 A;  4KM4 A;  3UN3 A;  4CXK A;  1KHJ A;  4QAX A;  3TWZ A;  1EW9 A;  1Y7A A;  2IUC A;  3WBH A;  4ZGA A;  1ELZ A;  1EW8 A;  1AJD A;  4QN0 A;  4MIV A;  3WAY A;  1ALI A;  4UOP A;  4MHX A;  3OT9 A;  1KH7 A;  4GTW A;  3NKM A;  5DLW A;  4LRF A;  3MK1 A;  4UPL A;  1EJJ A;  3NKR A;  1QAE A;  2W5V A;  1EQJ A;  4FDI A;  1HDH A;  2XGR A;  2ZKT A;  1P49 A;  4LRD A;  4MY4 A;  5AJ9 A;  5IJQ A;  5L0E A;  2GSU A;  2XR9 A;  2W8S A;  1ZEF A;  4CXU A;  4CYS A;  5TJ3 A;  2W5S A;  4UPH A;  5GOV A;  2W5Q A;  3T00 A;  4QH0 A;  4LRE A;  3SZZ A;  3UN2 A;  3NKQ A;  3LXQ A;  3MK0 A;  1HJK A;  1EW2 A;  3ISM A;  4GTY A;  2D1G A;  4YR1 A;  3TG0 A;  4LR2 A;  1SMN A;  3WAW A;  2RH6 A;  3NKP A;  3S5B A;  4E3Y A;  1FSU A;  4CXS A;  1K7H A;  4GTX A;  1KHL A;  1HQA A;  1E3C P;  2W5R A;  5HRT A;  3IDD A;  5C66 A;  5DLT A;  1SHQ A;  1Y6V A;  3DPC A;  4LR7 A;  4KAY A;  2W8D A;  4LRC A;  3ED4 A;  3WAX A;  2VQR A;  3UNY A;  5L0K A;  4TN0 A;  3E2D A;  3NKN A;  1ED8 A;  3B5Q A;  3M8Y A;  4QGO A;  2O3B A;  1URB A;  4UPI A;  1O99 A;  3UO0 A;  2XRG A;  3CMR A;  3OWV A;  1E1Z P;  5L0B A;  3BDG A;  4CYR A;  1ALJ A;  4NWX A;  5INH A;  2GSO A;  1ELY A;  2GSN A;  4UPK A;  3T02 A;  5GRR A;  5GKC A;  3T01 A;  5LRN A;  1AJC A; 
#chains in the Genus database with same CATH homology
 2ANH A;  1QL0 A;  2XH3 A;  1KH5 A;  1G8T A;  3M8W A;  2W5X A;  4N7T A;  2W5W A;  4KJD A;  2IUC B;  5KXA A;  1ANJ A;  1KH9 A;  1ALH A;  4GTZ A;  3TX0 A;  4UOO A;  1ZED A;  1AUK A;  1KH4 A;  4B56 A;  4FDJ A;  5DLV A;  3NKO A;  5EGE A;  3MK2 A;  5K4P A;  4NWJ A;  5EGH A;  3DYC A;  4LR9 A;  1ZM8 A;  4ZG9 A;  1KHK A;  1ZEB A;  3BDF A;  3IGY B;  3Q3Q A;  1ALK A;  3WAV A;  3NVL A;  3UN5 A;  2G9Y A;  1B8J A;  1EI6 A;  2GA3 A;  5GKP A;  1SHN A;  1ANI A;  2W5T A;  1URA A;  3IGZ B;  3A52 A;  1AJB A;  2GLQ A;  2IFY A;  3BDH A;  3SZY A;  1ED9 A;  1E2S P;  3BDG B;  4LRA A;  4ZG7 A;  1N2L A;  1O98 A;  4KJG A;  4UOR A;  1E33 P;  3M7V A;  1ELX A;  1N2K A;  2X98 A;  1AJA A;  5LRM A;  4LQY A;  4LR8 A;  4ZG6 A;  4A1N A;  4LRB A;  4KAV A;  5LIA A;  1KHN A;  3M8Z A;  5IJS A;  5LQQ A;  2QZU A;  3KD8 A;  4KM4 A;  3UN3 A;  4CXK A;  1KHJ A;  4QAX A;  3TWZ A;  1EW9 A;  1Y7A A;  2IUC A;  3WBH A;  4ZGA A;  1ELZ A;  1EW8 A;  1AJD A;  4QN0 A;  4MIV A;  3WAY A;  1ALI A;  4UOP A;  4MHX A;  3OT9 A;  1KH7 A;  4GTW A;  3NKM A;  5DLW A;  4LRF A;  3MK1 A;  4UPL A;  1EJJ A;  3NKR A;  1QAE A;  2W5V A;  1EQJ A;  4FDI A;  1HDH A;  2XGR A;  2ZKT A;  1P49 A;  4LRD A;  4MY4 A;  5AJ9 A;  5IJQ A;  5L0E A;  2GSU A;  2XR9 A;  2W8S A;  1ZEF A;  4CXU A;  4CYS A;  5TJ3 A;  2W5S A;  4UPH A;  5GOV A;  2W5Q A;  3T00 A;  4QH0 A;  4LRE A;  3SZZ A;  3UN2 A;  3NKQ A;  3LXQ A;  3MK0 A;  1HJK A;  1EW2 A;  3ISM A;  4GTY A;  2D1G A;  4YR1 A;  3TG0 A;  4LR2 A;  1SMN A;  3WAW A;  2RH6 A;  3NKP A;  3S5B A;  4E3Y A;  1FSU A;  4CXS A;  1K7H A;  4GTX A;  1KHL A;  1HQA A;  1E3C P;  2W5R A;  5HRT A;  3IDD A;  5C66 A;  5DLT A;  1SHQ A;  1Y6V A;  3DPC A;  4LR7 A;  4KAY A;  2W8D A;  4LRC A;  3ED4 A;  3WAX A;  2VQR A;  3UNY A;  5L0K A;  4TN0 A;  3E2D A;  3NKN A;  1ED8 A;  3B5Q A;  3M8Y A;  4QGO A;  2O3B A;  1URB A;  4UPI A;  1O99 A;  3UO0 A;  2XRG A;  3CMR A;  3OWV A;  1E1Z P;  5L0B A;  3BDG A;  4CYR A;  1ALJ A;  4NWX A;  5INH A;  2GSO A;  1ELY A;  2GSN A;  4UPK A;  3T02 A;  5GRR A;  5GKC A;  3T01 A;  5LRN A;  1AJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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