5L0OA

Iqgap1 calponin homology domain fragment (chdf) mutant k161c under oxidizing conditions
Total Genus 60
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
164
structure length
164
Chain Sequence
AEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFCLGLAPQIQDLYGKVDFTEEEINNMKTELEK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Ras GTPase-activating-like protein IQGAP1
total genus 60
structure length 164
sequence length 164
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2016-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 5l0oA00
2WA6A 4Q58A 1WYQA 4TXKA 3HOCA 1PXYA 1P5SA 1H67A 1P2XA 1AA2A 2R0OA 1TJTA 2K2RA 4Q57B 4EDNA 2D85A 2D88A 1RT8A 3REPB 2D89A 4EDMA 1WJOA 2WA7A 1WYNA 5L0OA 1QAGA 1WYRA 2JV9A 1SH6A 2QJZA 1WYMA 2RR8A 4Q59A 3F7PA 5A38A 2D87A 1VKAA 1UJOA 5A37A 2EE7A 3CO1A 1WIXA 5A4BA 1UEGA 1DXXA 1SH5A 2WA5A 2VZGB 1WYPA 2VZDA 2K3SA 1AOAA 1PA7A 2VZIB 3FERA 1V5KA 3JAKM 3HOPA 2WFNA 1BHDA 5J8EA 2VZCA 2EYNA 2YRNA 3HORA 4B7LA 3KMWB 2E9KA 3JALM 2L3GA 1WYLA 5BVRA 4TXIA 2DK9A 3KY9A 3JARM 1WKUA 5A36A 2EYIA 3I6XA 3KMUB 4EDLA 1BKRA 2R8UA 1WYOA 2D86A 1MB8A 2QJXA
chains in the Genus database with same CATH superfamily
2WA6A 4Q58A 1WYQA 5FMUA 4TXKA 5FMTA 3HOCA 1PXYA 1P5SA 1H67A 2WE6A 1P2XA 1AA2A 2R0OA 3VP7A 1TJTA 2K2RA 4Q57B 4EDNA 2D85A 2D88A 1RT8A 3REPB 2D89A 4EDMA 1WJOA 2WA7A 1WYNA 5L0OA 1QAGA 1WYRA 2JV9A 1SH6A 2QJZA 4LVRA 1WYMA 2RR8A 4DDPA 2HL9A 4LVPA 4Q59A 3F7PA 5A38A 2D87A 1VKAA 1UJOA 5A37A 2EE7A 2HL8A 3CO1A 1WIXA 5A4BA 1UEGA 1DXXA 1SH5A 2HKPA 2VE7A 2WA5A 2VZGB 1WYPA 2VZDA 1EUVA 1AOAA 2K3SA 1PA7A 2VZIB 3FERA 1V5KA 3JAKM 3EAYA 3HOPA 2WFNA 1BHDA 5J8EA 2VZCA 2EYNA 2YRNA 3HORA 4B7LA 3KMWB 2EQOA 2E9KA 3JALM 2L3GA 1WYLA 5BVRA 4TXIA 2DK9A 3KY9A 3JARM 1WKUA 5A36A 2EYIA 3I6XA 3KMUB 4EDLA 1BKRA 2WDTA 2R8UA 2IGPA 1WYOA 2D86A 1MB8A 2VE7C 2QJXA
chains in the Genus database with same CATH topology
2WA6A 4Q58A 1WYQA 4TXKA 3HOCA 1PXYA 1P5SA 1H67A 1P2XA 1AA2A 2R0OA 1TJTA 2K2RA 4Q57B 4EDNA 2D85A 2D88A 1RT8A 3REPB 2D89A 4EDMA 1WJOA 2WA7A 1WYNA 5L0OA 1QAGA 1WYRA 2JV9A 1SH6A 2QJZA 1WYMA 2RR8A 4Q59A 3F7PA 5A38A 2D87A 1VKAA 1UJOA 5A37A 2EE7A 3CO1A 1WIXA 5A4BA 1UEGA 1DXXA 1SH5A 2WA5A 2VZGB 1WYPA 2VZDA 2K3SA 1AOAA 1PA7A 2VZIB 3FERA 1V5KA 3JAKM 3HOPA 2WFNA 1BHDA 5J8EA 2VZCA 2EYNA 2YRNA 3HORA 4B7LA 3KMWB 2E9KA 3JALM 2L3GA 1WYLA 5BVRA 4TXIA 2DK9A 3KY9A 3JARM 1WKUA 5A36A 2EYIA 3I6XA 3KMUB 4EDLA 1BKRA 2R8UA 1WYOA 2D86A 1MB8A 2QJXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WA6 A;  4Q58 A;  1WYQ A;  4TXK A;  3HOC A;  1PXY A;  1P5S A;  1H67 A;  1P2X A;  1AA2 A;  2R0O A;  1TJT A;  2K2R A;  4Q57 B;  4EDN A;  2D85 A;  2D88 A;  1RT8 A;  3REP B;  2D89 A;  4EDM A;  1WJO A;  2WA7 A;  1WYN A;  5L0O A;  1QAG A;  1WYR A;  2JV9 A;  1SH6 A;  2QJZ A;  1WYM A;  2RR8 A;  4Q59 A;  3F7P A;  5A38 A;  2D87 A;  1VKA A;  1UJO A;  5A37 A;  2EE7 A;  3CO1 A;  1WIX A;  5A4B A;  1UEG A;  1DXX A;  1SH5 A;  2WA5 A;  2VZG B;  1WYP A;  2VZD A;  2K3S A;  1AOA A;  1PA7 A;  2VZI B;  3FER A;  1V5K A;  3JAK M;  3HOP A;  2WFN A;  1BHD A;  5J8E A;  2VZC A;  2EYN A;  2YRN A;  3HOR A;  4B7L A;  3KMW B;  2E9K A;  3JAL M;  2L3G A;  1WYL A;  5BVR A;  4TXI A;  2DK9 A;  3KY9 A;  3JAR M;  1WKU A;  5A36 A;  2EYI A;  3I6X A;  3KMU B;  4EDL A;  1BKR A;  2R8U A;  1WYO A;  2D86 A;  1MB8 A;  2QJX A; 
#chains in the Genus database with same CATH topology
 2WA6 A;  4Q58 A;  1WYQ A;  5FMU A;  4TXK A;  5FMT A;  3HOC A;  1PXY A;  1P5S A;  1H67 A;  2WE6 A;  1P2X A;  1AA2 A;  2R0O A;  3VP7 A;  1TJT A;  2K2R A;  4Q57 B;  4EDN A;  2D85 A;  2D88 A;  1RT8 A;  3REP B;  2D89 A;  4EDM A;  1WJO A;  2WA7 A;  1WYN A;  5L0O A;  1QAG A;  1WYR A;  2JV9 A;  1SH6 A;  2QJZ A;  4LVR A;  1WYM A;  2RR8 A;  4DDP A;  2HL9 A;  4LVP A;  4Q59 A;  3F7P A;  5A38 A;  2D87 A;  1VKA A;  1UJO A;  5A37 A;  2EE7 A;  2HL8 A;  3CO1 A;  1WIX A;  5A4B A;  1UEG A;  1DXX A;  1SH5 A;  2HKP A;  2VE7 A;  2WA5 A;  2VZG B;  1WYP A;  2VZD A;  1EUV A;  1AOA A;  2K3S A;  1PA7 A;  2VZI B;  3FER A;  1V5K A;  3JAK M;  3EAY A;  3HOP A;  2WFN A;  1BHD A;  5J8E A;  2VZC A;  2EYN A;  2YRN A;  3HOR A;  4B7L A;  3KMW B;  2EQO A;  2E9K A;  3JAL M;  2L3G A;  1WYL A;  5BVR A;  4TXI A;  2DK9 A;  3KY9 A;  3JAR M;  1WKU A;  5A36 A;  2EYI A;  3I6X A;  3KMU B;  4EDL A;  1BKR A;  2WDT A;  2R8U A;  2IGP A;  1WYO A;  2D86 A;  1MB8 A;  2VE7 C;  2QJX A; 
#chains in the Genus database with same CATH homology
 2WA6 A;  4Q58 A;  1WYQ A;  4TXK A;  3HOC A;  1PXY A;  1P5S A;  1H67 A;  1P2X A;  1AA2 A;  2R0O A;  1TJT A;  2K2R A;  4Q57 B;  4EDN A;  2D85 A;  2D88 A;  1RT8 A;  3REP B;  2D89 A;  4EDM A;  1WJO A;  2WA7 A;  1WYN A;  5L0O A;  1QAG A;  1WYR A;  2JV9 A;  1SH6 A;  2QJZ A;  1WYM A;  2RR8 A;  4Q59 A;  3F7P A;  5A38 A;  2D87 A;  1VKA A;  1UJO A;  5A37 A;  2EE7 A;  3CO1 A;  1WIX A;  5A4B A;  1UEG A;  1DXX A;  1SH5 A;  2WA5 A;  2VZG B;  1WYP A;  2VZD A;  2K3S A;  1AOA A;  1PA7 A;  2VZI B;  3FER A;  1V5K A;  3JAK M;  3HOP A;  2WFN A;  1BHD A;  5J8E A;  2VZC A;  2EYN A;  2YRN A;  3HOR A;  4B7L A;  3KMW B;  2E9K A;  3JAL M;  2L3G A;  1WYL A;  5BVR A;  4TXI A;  2DK9 A;  3KY9 A;  3JAR M;  1WKU A;  5A36 A;  2EYI A;  3I6X A;  3KMU B;  4EDL A;  1BKR A;  2R8U A;  1WYO A;  2D86 A;  1MB8 A;  2QJX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...