5L3LA

D11 bound igf-ii
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3lA00
2L29B 2KQPA 2DSRI 1IGLA 1TGRA 2KJIA 2DSQC 3LRIA 5L3MA 1PMXA 2DSPI 2LWZA 5L3LA 1H59A 3GF1A 6INSE 1ZEIA 1H02B 1SJUA 1GZYB 4XSSB 5L3NA 1BQTA 1WQJI 2GF1A 1GZZB 1GZRB 1B9GA 1EFEA 1IMXA 3KR3D 2JZQA
chains in the Genus database with same CATH superfamily
2L29B 2KQPA 2DSRI 1IGLA 1TGRA 2KJIA 2DSQC 3LRIA 3F2DA 3F2CA 5L3MA 1PMXA 2DSPI 2LWZA 5L3LA 1H59A 3GF1A 6INSE 1ZEIA 1H02B 1SJUA 1GZYB 4XSSB 5L3NA 1BQTA 1WQJI 2L14B 2GF1A 1GZZB 1GZRB 1B9GA 3F2BA 1EFEA 1IMXA 3KR3D 2JZQA
chains in the Genus database with same CATH topology
2L29B 2KQPA 2DSRI 1IGLA 1TGRA 2KJIA 2DSQC 3LRIA 5L3MA 1PMXA 2DSPI 2LWZA 5L3LA 1H59A 3GF1A 6INSE 1ZEIA 1H02B 1SJUA 1GZYB 4XSSB 5L3NA 1BQTA 1WQJI 2GF1A 1GZZB 1GZRB 1B9GA 1EFEA 1IMXA 3KR3D 2JZQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L29 B;  2KQP A;  2DSR I;  1IGL A;  1TGR A;  2KJI A;  2DSQ C;  3LRI A;  5L3M A;  1PMX A;  2DSP I;  2LWZ A;  5L3L A;  1H59 A;  3GF1 A;  6INS E;  1ZEI A;  1H02 B;  1SJU A;  1GZY B;  4XSS B;  5L3N A;  1BQT A;  1WQJ I;  2GF1 A;  1GZZ B;  1GZR B;  1B9G A;  1EFE A;  1IMX A;  3KR3 D;  2JZQ A; 
#chains in the Genus database with same CATH topology
 2L29 B;  2KQP A;  2DSR I;  1IGL A;  1TGR A;  2KJI A;  2DSQ C;  3LRI A;  3F2D A;  3F2C A;  5L3M A;  1PMX A;  2DSP I;  2LWZ A;  5L3L A;  1H59 A;  3GF1 A;  6INS E;  1ZEI A;  1H02 B;  1SJU A;  1GZY B;  4XSS B;  5L3N A;  1BQT A;  1WQJ I;  2L14 B;  2GF1 A;  1GZZ B;  1GZR B;  1B9G A;  3F2B A;  1EFE A;  1IMX A;  3KR3 D;  2JZQ A; 
#chains in the Genus database with same CATH homology
 2L29 B;  2KQP A;  2DSR I;  1IGL A;  1TGR A;  2KJI A;  2DSQ C;  3LRI A;  5L3M A;  1PMX A;  2DSP I;  2LWZ A;  5L3L A;  1H59 A;  3GF1 A;  6INS E;  1ZEI A;  1H02 B;  1SJU A;  1GZY B;  4XSS B;  5L3N A;  1BQT A;  1WQJ I;  2GF1 A;  1GZZ B;  1GZR B;  1B9G A;  1EFE A;  1IMX A;  3KR3 D;  2JZQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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