5L3NA

D11 bound [n29, s39_pq]-igf-ii
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
69
structure length
69
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFNRPASRVSRRSPQRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 69
sequence length 69
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3nA00
1SJUA 1IGLA 1GZRB 2KQPA 1IMXA 3GF1A 2L29B 1GZYB 1ZEIA 3LRIA 2DSPI 2LWZA 5L3MA 1TGRA 1H02B 1B9GA 3KR3D 1EFEA 2KJIA 1GZZB 1BQTA 1H59A 2DSRI 1WQJI 4XSSB 2DSQC 2JZQA 6INSE 1PMXA 2GF1A 5L3LA 5L3NA
chains in the Genus database with same CATH superfamily
1SJUA 1IGLA 1GZRB 2KQPA 1IMXA 3GF1A 2L14B 2L29B 1GZYB 1ZEIA 3LRIA 2DSPI 2LWZA 5L3MA 1TGRA 3F2BA 1H02B 3F2DA 1B9GA 3KR3D 1EFEA 2KJIA 1GZZB 1BQTA 1H59A 2DSRI 1WQJI 4XSSB 2DSQC 2JZQA 6INSE 3F2CA 1PMXA 2GF1A 5L3LA 5L3NA
chains in the Genus database with same CATH topology
1SJUA 1IGLA 1GZRB 2KQPA 1IMXA 3GF1A 2L29B 1GZYB 1ZEIA 3LRIA 2DSPI 2LWZA 5L3MA 1TGRA 1H02B 1B9GA 3KR3D 1EFEA 2KJIA 1GZZB 1BQTA 1H59A 2DSRI 1WQJI 4XSSB 2DSQC 2JZQA 6INSE 1PMXA 2GF1A 5L3LA 5L3NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SJU A;  1IGL A;  1GZR B;  2KQP A;  1IMX A;  3GF1 A;  2L29 B;  1GZY B;  1ZEI A;  3LRI A;  2DSP I;  2LWZ A;  5L3M A;  1TGR A;  1H02 B;  1B9G A;  3KR3 D;  1EFE A;  2KJI A;  1GZZ B;  1BQT A;  1H59 A;  2DSR I;  1WQJ I;  4XSS B;  2DSQ C;  2JZQ A;  6INS E;  1PMX A;  2GF1 A;  5L3L A;  5L3N A; 
#chains in the Genus database with same CATH topology
 1SJU A;  1IGL A;  1GZR B;  2KQP A;  1IMX A;  3GF1 A;  2L14 B;  2L29 B;  1GZY B;  1ZEI A;  3LRI A;  2DSP I;  2LWZ A;  5L3M A;  1TGR A;  3F2B A;  1H02 B;  3F2D A;  1B9G A;  3KR3 D;  1EFE A;  2KJI A;  1GZZ B;  1BQT A;  1H59 A;  2DSR I;  1WQJ I;  4XSS B;  2DSQ C;  2JZQ A;  6INS E;  3F2C A;  1PMX A;  2GF1 A;  5L3L A;  5L3N A; 
#chains in the Genus database with same CATH homology
 1SJU A;  1IGL A;  1GZR B;  2KQP A;  1IMX A;  3GF1 A;  2L29 B;  1GZY B;  1ZEI A;  3LRI A;  2DSP I;  2LWZ A;  5L3M A;  1TGR A;  1H02 B;  1B9G A;  3KR3 D;  1EFE A;  2KJI A;  1GZZ B;  1BQT A;  1H59 A;  2DSR I;  1WQJ I;  4XSS B;  2DSQ C;  2JZQ A;  6INS E;  1PMX A;  2GF1 A;  5L3L A;  5L3N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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