5LU1A

Human 14-3-3 sigma clu3 mutant complexed with short hspb6 phosphopeptide
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
230
structure length
225
Chain Sequence
ERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEAGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 95
structure length 225
sequence length 230
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2016-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5lu1A00
4E2EA 4N7YA 3P1OA 4DHRA 1O9EA 1YZ5A 3P1PA 3IQJA 4Y3BA 4JDDA 1A4OA 2WH0A 5D3EA 1O9DA 3MHRA 4J6SA 5F74A 2O02A 2C63A 4DHMA 4IEAA 1A37A 5EXAA 3O8IA 4WRQA 4F7RA 1QJBA 5D2DA 4FJ3A 1A38A 4JC3A 3NKXA 4DX0A 3LW1A 3SMNA 3U9XA 5LU1A 3CU8A 4IHLA 3P1SA 3UZDA 3AXYC 2BTPA 3P1RA 4N84A 3UX0A 2BR9A 5LVZA 2V7DA 5HF3A 2BQ0A 4Y32A 3P1NA 5D3FA 3RDHA 3SMKA 2C23A 4N7GA 3SMLA 4FL5A 3T0LA 5IQPA 4FR3A 5J31A 1O9FA 5LU2A 4QLIA 2C1NA 4ZQ0A 4DAUA 3UBWA 3IQVA 4O46A 4ZDRA 3SP5A 1YWTA 3UALA 4Y5IA 2NPMA 4HKCA 4DHUA 5BY9A 2O98A 3E6YA 5EWZA 4DHOA 3IQUA 4DHTA 4DHPA 4DHQA 5BTVA 2O8PA 4DATA 5LHOA 2B05A 4BG6A 1O9CA 3EFZA 1IB1A 2C1JA 3SMOA 4GNTA 3SPRA 4DHSA 3M50A 3T0MA 4DHNA 4DNKA 2C74A 3M51A 5LX2A 3P1QA 3SMMA 1QJAA
chains in the Genus database with same CATH superfamily
4E2EA 4N7YA 3P1OA 1S2XA 4DHRA 4W8JA 1O9EA 1YZ5A 3P1PA 4QX2A 3IQJA 4Y3BA 4JDDA 1A4OA 2WH0A 5D3EA 1O9DA 3MHRA 1DLCA 3CQCA 4J6SA 5F74A 4QX1A 2O02A 2C63A 4DHMA 4IEAA 1A37A 5EXAA 3O8IA 4WRQA 4F7RA 1QJBA 4FJ3A 5D2DA 1A38A 4JC3A 3NKXA 4DX0A 3LW1A 3SMNA 3U9XA 5LU1A 3CU8A 4IHLA 3P1SA 3UZDA 3AXYC 2BTPA 3X0UA 3P1RA 4N84A 4ARXA 1CIYA 3UX0A 2BR9A 3I4RA 5LVZA 2V7DA 4QX0A 5HF3A 4QX3A 2BQ0A 4D8MA 4Y32A 3P1NA 5D3FA 3RDHA 3SMKA 2C23A 4N7GA 3SMLA 4FL5A 3T0LA 5IQPA 4FR3A 5J31A 1O9FA 3CQGA 5LU2A 4QLIA 2C1NA 4ZQ0A 4DAUA 3UBWA 3IQVA 4O46A 4ZDRA 3SP5A 1URJA 4ARYA 1YWTA 3UALA 4Y5IA 2NPMA 4HKCA 4DHUA 1JI6A 2C9KA 5BY9A 2O98A 3E6YA 5EWZA 4DHOA 3IQUA 4DHTA 4DHPA 4DHQA 3EB7A 5BTVA 2O8PA 4DATA 5LHOA 2B05A 4BG6A 1O9CA 3ZHEB 3EFZA 4MOAA 1IB1A 2C1JA 3SMOA 4GNTA 3SPRA 4DHSA 3M50A 3T0MA 4DHNA 1W99A 4DNKA 2C74A 3M51A 5LX2A 3P1QA 3SMMA 1I5PA 1QJAA
chains in the Genus database with same CATH topology
4E2EA 4N7YA 3P1OA 4DHRA 1O9EA 1YZ5A 3P1PA 3IQJA 4Y3BA 4JDDA 1A4OA 2WH0A 5D3EA 1O9DA 3MHRA 4J6SA 5F74A 2O02A 2C63A 4DHMA 4IEAA 1A37A 5EXAA 3O8IA 4WRQA 4F7RA 1QJBA 5D2DA 4FJ3A 1A38A 4JC3A 3NKXA 4DX0A 3LW1A 3SMNA 3U9XA 5LU1A 3CU8A 4IHLA 3P1SA 3UZDA 3AXYC 2BTPA 3P1RA 4N84A 3UX0A 2BR9A 5LVZA 2V7DA 5HF3A 2BQ0A 4Y32A 3P1NA 5D3FA 3RDHA 3SMKA 2C23A 4N7GA 3SMLA 4FL5A 3T0LA 5IQPA 4FR3A 5J31A 1O9FA 5LU2A 4QLIA 2C1NA 4ZQ0A 4DAUA 3UBWA 3IQVA 4O46A 4ZDRA 3SP5A 1YWTA 3UALA 4Y5IA 2NPMA 4HKCA 4DHUA 5BY9A 2O98A 3E6YA 5EWZA 4DHOA 3IQUA 4DHTA 4DHPA 4DHQA 5BTVA 2O8PA 4DATA 5LHOA 2B05A 4BG6A 1O9CA 3EFZA 1IB1A 2C1JA 3SMOA 4GNTA 3SPRA 4DHSA 3M50A 3T0MA 4DHNA 4DNKA 2C74A 3M51A 5LX2A 3P1QA 3SMMA 1QJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E2E A;  4N7Y A;  3P1O A;  4DHR A;  1O9E A;  1YZ5 A;  3P1P A;  3IQJ A;  4Y3B A;  4JDD A;  1A4O A;  2WH0 A;  5D3E A;  1O9D A;  3MHR A;  4J6S A;  5F74 A;  2O02 A;  2C63 A;  4DHM A;  4IEA A;  1A37 A;  5EXA A;  3O8I A;  4WRQ A;  4F7R A;  1QJB A;  5D2D A;  4FJ3 A;  1A38 A;  4JC3 A;  3NKX A;  4DX0 A;  3LW1 A;  3SMN A;  3U9X A;  5LU1 A;  3CU8 A;  4IHL A;  3P1S A;  3UZD A;  3AXY C;  2BTP A;  3P1R A;  4N84 A;  3UX0 A;  2BR9 A;  5LVZ A;  2V7D A;  5HF3 A;  2BQ0 A;  4Y32 A;  3P1N A;  5D3F A;  3RDH A;  3SMK A;  2C23 A;  4N7G A;  3SML A;  4FL5 A;  3T0L A;  5IQP A;  4FR3 A;  5J31 A;  1O9F A;  5LU2 A;  4QLI A;  2C1N A;  4ZQ0 A;  4DAU A;  3UBW A;  3IQV A;  4O46 A;  4ZDR A;  3SP5 A;  1YWT A;  3UAL A;  4Y5I A;  2NPM A;  4HKC A;  4DHU A;  5BY9 A;  2O98 A;  3E6Y A;  5EWZ A;  4DHO A;  3IQU A;  4DHT A;  4DHP A;  4DHQ A;  5BTV A;  2O8P A;  4DAT A;  5LHO A;  2B05 A;  4BG6 A;  1O9C A;  3EFZ A;  1IB1 A;  2C1J A;  3SMO A;  4GNT A;  3SPR A;  4DHS A;  3M50 A;  3T0M A;  4DHN A;  4DNK A;  2C74 A;  3M51 A;  5LX2 A;  3P1Q A;  3SMM A;  1QJA A; 
#chains in the Genus database with same CATH topology
 4E2E A;  4N7Y A;  3P1O A;  1S2X A;  4DHR A;  4W8J A;  1O9E A;  1YZ5 A;  3P1P A;  4QX2 A;  3IQJ A;  4Y3B A;  4JDD A;  1A4O A;  2WH0 A;  5D3E A;  1O9D A;  3MHR A;  1DLC A;  3CQC A;  4J6S A;  5F74 A;  4QX1 A;  2O02 A;  2C63 A;  4DHM A;  4IEA A;  1A37 A;  5EXA A;  3O8I A;  4WRQ A;  4F7R A;  1QJB A;  4FJ3 A;  5D2D A;  1A38 A;  4JC3 A;  3NKX A;  4DX0 A;  3LW1 A;  3SMN A;  3U9X A;  5LU1 A;  3CU8 A;  4IHL A;  3P1S A;  3UZD A;  3AXY C;  2BTP A;  3X0U A;  3P1R A;  4N84 A;  4ARX A;  1CIY A;  3UX0 A;  2BR9 A;  3I4R A;  5LVZ A;  2V7D A;  4QX0 A;  5HF3 A;  4QX3 A;  2BQ0 A;  4D8M A;  4Y32 A;  3P1N A;  5D3F A;  3RDH A;  3SMK A;  2C23 A;  4N7G A;  3SML A;  4FL5 A;  3T0L A;  5IQP A;  4FR3 A;  5J31 A;  1O9F A;  3CQG A;  5LU2 A;  4QLI A;  2C1N A;  4ZQ0 A;  4DAU A;  3UBW A;  3IQV A;  4O46 A;  4ZDR A;  3SP5 A;  1URJ A;  4ARY A;  1YWT A;  3UAL A;  4Y5I A;  2NPM A;  4HKC A;  4DHU A;  1JI6 A;  2C9K A;  5BY9 A;  2O98 A;  3E6Y A;  5EWZ A;  4DHO A;  3IQU A;  4DHT A;  4DHP A;  4DHQ A;  3EB7 A;  5BTV A;  2O8P A;  4DAT A;  5LHO A;  2B05 A;  4BG6 A;  1O9C A;  3ZHE B;  3EFZ A;  4MOA A;  1IB1 A;  2C1J A;  3SMO A;  4GNT A;  3SPR A;  4DHS A;  3M50 A;  3T0M A;  4DHN A;  1W99 A;  4DNK A;  2C74 A;  3M51 A;  5LX2 A;  3P1Q A;  3SMM A;  1I5P A;  1QJA A; 
#chains in the Genus database with same CATH homology
 4E2E A;  4N7Y A;  3P1O A;  4DHR A;  1O9E A;  1YZ5 A;  3P1P A;  3IQJ A;  4Y3B A;  4JDD A;  1A4O A;  2WH0 A;  5D3E A;  1O9D A;  3MHR A;  4J6S A;  5F74 A;  2O02 A;  2C63 A;  4DHM A;  4IEA A;  1A37 A;  5EXA A;  3O8I A;  4WRQ A;  4F7R A;  1QJB A;  5D2D A;  4FJ3 A;  1A38 A;  4JC3 A;  3NKX A;  4DX0 A;  3LW1 A;  3SMN A;  3U9X A;  5LU1 A;  3CU8 A;  4IHL A;  3P1S A;  3UZD A;  3AXY C;  2BTP A;  3P1R A;  4N84 A;  3UX0 A;  2BR9 A;  5LVZ A;  2V7D A;  5HF3 A;  2BQ0 A;  4Y32 A;  3P1N A;  5D3F A;  3RDH A;  3SMK A;  2C23 A;  4N7G A;  3SML A;  4FL5 A;  3T0L A;  5IQP A;  4FR3 A;  5J31 A;  1O9F A;  5LU2 A;  4QLI A;  2C1N A;  4ZQ0 A;  4DAU A;  3UBW A;  3IQV A;  4O46 A;  4ZDR A;  3SP5 A;  1YWT A;  3UAL A;  4Y5I A;  2NPM A;  4HKC A;  4DHU A;  5BY9 A;  2O98 A;  3E6Y A;  5EWZ A;  4DHO A;  3IQU A;  4DHT A;  4DHP A;  4DHQ A;  5BTV A;  2O8P A;  4DAT A;  5LHO A;  2B05 A;  4BG6 A;  1O9C A;  3EFZ A;  1IB1 A;  2C1J A;  3SMO A;  4GNT A;  3SPR A;  4DHS A;  3M50 A;  3T0M A;  4DHN A;  4DNK A;  2C74 A;  3M51 A;  5LX2 A;  3P1Q A;  3SMM A;  1QJA A; 
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