5LU2A

Human 14-3-3 sigma complexed with long hspb6 phosphopeptide
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
230
structure length
230
Chain Sequence
ERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 96
structure length 230
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5lu2A00
3NKXA 3IQVA 2NPMA 3P1RA 5F74A 1YZ5A 4DHPA 2C63A 2BQ0A 3IQUA 3CU8A 3UZDA 4Y5IA 3SMKA 3M50A 3SMLA 3P1OA 3U9XA 4FJ3A 4N7YA 3P1QA 2V7DA 2C1NA 5LHOA 2O02A 4DHOA 5BY9A 4DNKA 2O8PA 3AXYC 4DX0A 3SPRA 1O9CA 2C23A 3UALA 4F7RA 1YWTA 2O98A 3P1PA 4IEAA 4DHRA 4ZQ0A 3P1SA 3LW1A 3T0MA 3E6YA 4Y32A 4DHSA 4FL5A 4N84A 1O9DA 3IQJA 5D3FA 5EXAA 4DHMA 4O46A 4DHNA 4DATA 2B05A 4QLIA 4JC3A 3M51A 4WRQA 1O9FA 1A38A 2WH0A 4JDDA 4BG6A 1QJAA 1A4OA 2BR9A 5D2DA 3SMOA 4ZDRA 5BTVA 5LU2A 3SMMA 5LX2A 2C74A 1IB1A 3EFZA 1O9EA 3UX0A 4IHLA 1A37A 5IQPA 3RDHA 3T0LA 4DAUA 5EWZA 4J6SA 3UBWA 2BTPA 4E2EA 4N7GA 3SP5A 3MHRA 4HKCA 5HF3A 4DHTA 1QJBA 4DHUA 5LVZA 4GNTA 4Y3BA 5J31A 3SMNA 3O8IA 5D3EA 3P1NA 4FR3A 5LU1A 2C1JA 4DHQA
chains in the Genus database with same CATH superfamily
3NKXA 3IQVA 1S2XA 2NPMA 3P1RA 4QX0A 5F74A 1YZ5A 4DHPA 2C63A 2BQ0A 3IQUA 3CU8A 2C9KA 3UZDA 4Y5IA 3SMKA 3M50A 3SMLA 3P1OA 3U9XA 4FJ3A 4N7YA 3P1QA 2V7DA 2C1NA 5LHOA 2O02A 4DHOA 5BY9A 3I4RA 4DNKA 2O8PA 3AXYC 4DX0A 3SPRA 1I5PA 1O9CA 2C23A 3UALA 4F7RA 1YWTA 2O98A 3P1PA 4IEAA 4DHRA 1DLCA 4ZQ0A 3P1SA 3LW1A 3T0MA 3E6YA 1W99A 4Y32A 4ARYA 4DHSA 4FL5A 4N84A 1O9DA 3IQJA 5D3FA 4QX3A 5EXAA 3X0UA 4DHMA 4O46A 4DHNA 4DATA 2B05A 4QLIA 4JC3A 3M51A 4WRQA 1O9FA 1A38A 2WH0A 4JDDA 4BG6A 1QJAA 1A4OA 2BR9A 5D2DA 3SMOA 4ZDRA 5BTVA 5LU2A 3SMMA 5LX2A 2C74A 3EB7A 1IB1A 3EFZA 4MOAA 1O9EA 3UX0A 4IHLA 1CIYA 1A37A 4D8MA 5IQPA 3RDHA 3T0LA 4DAUA 3CQGA 5EWZA 4J6SA 3UBWA 1URJA 2BTPA 4E2EA 4N7GA 3SP5A 3MHRA 4HKCA 4QX2A 5HF3A 4QX1A 4ARXA 4DHTA 1QJBA 4W8JA 4DHUA 4GNTA 5LVZA 3CQCA 4Y3BA 5J31A 3SMNA 3O8IA 5D3EA 1JI6A 3P1NA 4FR3A 5LU1A 2C1JA 3ZHEB 4DHQA
chains in the Genus database with same CATH topology
3NKXA 3IQVA 2NPMA 3P1RA 5F74A 1YZ5A 4DHPA 2C63A 2BQ0A 3IQUA 3CU8A 3UZDA 4Y5IA 3SMKA 3M50A 3SMLA 3P1OA 3U9XA 4FJ3A 4N7YA 3P1QA 2V7DA 2C1NA 5LHOA 2O02A 4DHOA 5BY9A 4DNKA 2O8PA 3AXYC 4DX0A 3SPRA 1O9CA 2C23A 3UALA 4F7RA 1YWTA 2O98A 3P1PA 4IEAA 4DHRA 4ZQ0A 3P1SA 3LW1A 3T0MA 3E6YA 4Y32A 4DHSA 4FL5A 4N84A 1O9DA 3IQJA 5D3FA 5EXAA 4DHMA 4O46A 4DHNA 4DATA 2B05A 4QLIA 4JC3A 3M51A 4WRQA 1O9FA 1A38A 2WH0A 4JDDA 4BG6A 1QJAA 1A4OA 2BR9A 5D2DA 3SMOA 4ZDRA 5BTVA 5LU2A 3SMMA 5LX2A 2C74A 1IB1A 3EFZA 1O9EA 3UX0A 4IHLA 1A37A 5IQPA 3RDHA 3T0LA 4DAUA 5EWZA 4J6SA 3UBWA 2BTPA 4E2EA 4N7GA 3SP5A 3MHRA 4HKCA 5HF3A 4DHTA 1QJBA 4DHUA 5LVZA 4GNTA 4Y3BA 5J31A 3SMNA 3O8IA 5D3EA 3P1NA 4FR3A 5LU1A 2C1JA 4DHQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKX A;  3IQV A;  2NPM A;  3P1R A;  5F74 A;  1YZ5 A;  4DHP A;  2C63 A;  2BQ0 A;  3IQU A;  3CU8 A;  3UZD A;  4Y5I A;  3SMK A;  3M50 A;  3SML A;  3P1O A;  3U9X A;  4FJ3 A;  4N7Y A;  3P1Q A;  2V7D A;  2C1N A;  5LHO A;  2O02 A;  4DHO A;  5BY9 A;  4DNK A;  2O8P A;  3AXY C;  4DX0 A;  3SPR A;  1O9C A;  2C23 A;  3UAL A;  4F7R A;  1YWT A;  2O98 A;  3P1P A;  4IEA A;  4DHR A;  4ZQ0 A;  3P1S A;  3LW1 A;  3T0M A;  3E6Y A;  4Y32 A;  4DHS A;  4FL5 A;  4N84 A;  1O9D A;  3IQJ A;  5D3F A;  5EXA A;  4DHM A;  4O46 A;  4DHN A;  4DAT A;  2B05 A;  4QLI A;  4JC3 A;  3M51 A;  4WRQ A;  1O9F A;  1A38 A;  2WH0 A;  4JDD A;  4BG6 A;  1QJA A;  1A4O A;  2BR9 A;  5D2D A;  3SMO A;  4ZDR A;  5BTV A;  5LU2 A;  3SMM A;  5LX2 A;  2C74 A;  1IB1 A;  3EFZ A;  1O9E A;  3UX0 A;  4IHL A;  1A37 A;  5IQP A;  3RDH A;  3T0L A;  4DAU A;  5EWZ A;  4J6S A;  3UBW A;  2BTP A;  4E2E A;  4N7G A;  3SP5 A;  3MHR A;  4HKC A;  5HF3 A;  4DHT A;  1QJB A;  4DHU A;  5LVZ A;  4GNT A;  4Y3B A;  5J31 A;  3SMN A;  3O8I A;  5D3E A;  3P1N A;  4FR3 A;  5LU1 A;  2C1J A;  4DHQ A; 
#chains in the Genus database with same CATH topology
 3NKX A;  3IQV A;  1S2X A;  2NPM A;  3P1R A;  4QX0 A;  5F74 A;  1YZ5 A;  4DHP A;  2C63 A;  2BQ0 A;  3IQU A;  3CU8 A;  2C9K A;  3UZD A;  4Y5I A;  3SMK A;  3M50 A;  3SML A;  3P1O A;  3U9X A;  4FJ3 A;  4N7Y A;  3P1Q A;  2V7D A;  2C1N A;  5LHO A;  2O02 A;  4DHO A;  5BY9 A;  3I4R A;  4DNK A;  2O8P A;  3AXY C;  4DX0 A;  3SPR A;  1I5P A;  1O9C A;  2C23 A;  3UAL A;  4F7R A;  1YWT A;  2O98 A;  3P1P A;  4IEA A;  4DHR A;  1DLC A;  4ZQ0 A;  3P1S A;  3LW1 A;  3T0M A;  3E6Y A;  1W99 A;  4Y32 A;  4ARY A;  4DHS A;  4FL5 A;  4N84 A;  1O9D A;  3IQJ A;  5D3F A;  4QX3 A;  5EXA A;  3X0U A;  4DHM A;  4O46 A;  4DHN A;  4DAT A;  2B05 A;  4QLI A;  4JC3 A;  3M51 A;  4WRQ A;  1O9F A;  1A38 A;  2WH0 A;  4JDD A;  4BG6 A;  1QJA A;  1A4O A;  2BR9 A;  5D2D A;  3SMO A;  4ZDR A;  5BTV A;  5LU2 A;  3SMM A;  5LX2 A;  2C74 A;  3EB7 A;  1IB1 A;  3EFZ A;  4MOA A;  1O9E A;  3UX0 A;  4IHL A;  1CIY A;  1A37 A;  4D8M A;  5IQP A;  3RDH A;  3T0L A;  4DAU A;  3CQG A;  5EWZ A;  4J6S A;  3UBW A;  1URJ A;  2BTP A;  4E2E A;  4N7G A;  3SP5 A;  3MHR A;  4HKC A;  4QX2 A;  5HF3 A;  4QX1 A;  4ARX A;  4DHT A;  1QJB A;  4W8J A;  4DHU A;  4GNT A;  5LVZ A;  3CQC A;  4Y3B A;  5J31 A;  3SMN A;  3O8I A;  5D3E A;  1JI6 A;  3P1N A;  4FR3 A;  5LU1 A;  2C1J A;  3ZHE B;  4DHQ A; 
#chains in the Genus database with same CATH homology
 3NKX A;  3IQV A;  2NPM A;  3P1R A;  5F74 A;  1YZ5 A;  4DHP A;  2C63 A;  2BQ0 A;  3IQU A;  3CU8 A;  3UZD A;  4Y5I A;  3SMK A;  3M50 A;  3SML A;  3P1O A;  3U9X A;  4FJ3 A;  4N7Y A;  3P1Q A;  2V7D A;  2C1N A;  5LHO A;  2O02 A;  4DHO A;  5BY9 A;  4DNK A;  2O8P A;  3AXY C;  4DX0 A;  3SPR A;  1O9C A;  2C23 A;  3UAL A;  4F7R A;  1YWT A;  2O98 A;  3P1P A;  4IEA A;  4DHR A;  4ZQ0 A;  3P1S A;  3LW1 A;  3T0M A;  3E6Y A;  4Y32 A;  4DHS A;  4FL5 A;  4N84 A;  1O9D A;  3IQJ A;  5D3F A;  5EXA A;  4DHM A;  4O46 A;  4DHN A;  4DAT A;  2B05 A;  4QLI A;  4JC3 A;  3M51 A;  4WRQ A;  1O9F A;  1A38 A;  2WH0 A;  4JDD A;  4BG6 A;  1QJA A;  1A4O A;  2BR9 A;  5D2D A;  3SMO A;  4ZDR A;  5BTV A;  5LU2 A;  3SMM A;  5LX2 A;  2C74 A;  1IB1 A;  3EFZ A;  1O9E A;  3UX0 A;  4IHL A;  1A37 A;  5IQP A;  3RDH A;  3T0L A;  4DAU A;  5EWZ A;  4J6S A;  3UBW A;  2BTP A;  4E2E A;  4N7G A;  3SP5 A;  3MHR A;  4HKC A;  5HF3 A;  4DHT A;  1QJB A;  4DHU A;  5LVZ A;  4GNT A;  4Y3B A;  5J31 A;  3SMN A;  3O8I A;  5D3E A;  3P1N A;  4FR3 A;  5LU1 A;  2C1J A;  4DHQ A; 
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