5LVZA

Crystal structure of yeast 14-3-3 protein from lachancea thermotolerans
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
235
structure length
235
Chain Sequence
SREDSVYLAKLAEQAERYEEMVDSMKAVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEEAKDKSEHQVKLIRDYRSKIETELTKICDDILSVLDTHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGEVRDKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Lachancea thermotolerans (strain atcc 56472 / cbs 6340 / nrrl y-8284)
molecule keywords KLTH0G14146p
total genus 110
structure length 235
sequence length 235
ec nomenclature
pdb deposition date 2016-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5lvzA00
4DHMA 5HF3A 1O9FA 3AXYC 2BR9A 3IQJA 1A4OA 3LW1A 2O98A 3CU8A 2C23A 4FR3A 5EWZA 4DAUA 5J31A 3P1QA 3P1PA 4WRQA 3SP5A 1A38A 3T0MA 4F7RA 4FL5A 3M51A 2O02A 1QJBA 4JDDA 5LVZA 5D3FA 4N7YA 3UALA 5D2DA 5LHOA 3SMKA 3SMLA 5F74A 4Y3BA 3UX0A 3EFZA 3U9XA 2V7DA 1QJAA 4JC3A 2C74A 3UZDA 3IQUA 5BTVA 4N7GA 2B05A 5D3EA 4J6SA 2NPMA 1A37A 3UBWA 1YWTA 1YZ5A 4DHNA 2WH0A 3SMOA 4BG6A 4DHQA 1O9CA 3P1RA 2O8PA 5IQPA 3SPRA 3P1OA 5LX2A 2BQ0A 4DHPA 5LU1A 4O46A 2C1NA 4QLIA 4N84A 3RDHA 4DHRA 4DHTA 1IB1A 4HKCA 3P1NA 3SMNA 3M50A 4Y32A 4DX0A 3O8IA 5LU2A 4Y5IA 4DNKA 4ZQ0A 3NKXA 4GNTA 4E2EA 3E6YA 3SMMA 3P1SA 4IEAA 4ZDRA 2BTPA 1O9DA 4DATA 4FJ3A 5EXAA 3IQVA 2C1JA 1O9EA 4DHOA 4DHSA 2C63A 3T0LA 4IHLA 5BY9A 3MHRA 4DHUA
chains in the Genus database with same CATH superfamily
4DHMA 5HF3A 1O9FA 4ARYA 1JI6A 3AXYC 2BR9A 3IQJA 1A4OA 3LW1A 2O98A 3CU8A 4QX2A 2C23A 4FR3A 5EWZA 4DAUA 5J31A 3P1QA 3P1PA 4WRQA 3SP5A 1A38A 2C9KA 4MOAA 3T0MA 4F7RA 4FL5A 3M51A 2O02A 4D8MA 1QJBA 4JDDA 5LVZA 5D3FA 4N7YA 3UALA 5D2DA 5LHOA 3SMKA 3SMLA 5F74A 4Y3BA 3UX0A 3EFZA 3U9XA 2V7DA 1QJAA 4JC3A 2C74A 4QX0A 3UZDA 1URJA 3IQUA 4ARXA 5BTVA 4N7GA 2B05A 1W99A 1DLCA 3EB7A 5D3EA 4J6SA 2NPMA 1A37A 3UBWA 1YWTA 1YZ5A 4DHNA 2WH0A 3SMOA 4BG6A 4DHQA 1CIYA 1O9CA 3P1RA 2O8PA 5IQPA 3SPRA 3P1OA 5LX2A 2BQ0A 4DHPA 5LU1A 4O46A 2C1NA 4QLIA 4N84A 3RDHA 4DHRA 3I4RA 4DHTA 1IB1A 4HKCA 3P1NA 3SMNA 3M50A 4Y32A 4DX0A 3O8IA 5LU2A 4W8JA 4Y5IA 4DNKA 4ZQ0A 3NKXA 4GNTA 4E2EA 1I5PA 3E6YA 3SMMA 3CQCA 3P1SA 4QX1A 1S2XA 4IEAA 4ZDRA 2BTPA 1O9DA 4DATA 4FJ3A 3X0UA 5EXAA 3IQVA 3ZHEB 2C1JA 1O9EA 4DHOA 4DHSA 2C63A 4QX3A 3T0LA 3CQGA 4IHLA 5BY9A 3MHRA 4DHUA
chains in the Genus database with same CATH topology
4DHMA 5HF3A 1O9FA 3AXYC 2BR9A 3IQJA 1A4OA 3LW1A 2O98A 3CU8A 2C23A 4FR3A 5EWZA 4DAUA 5J31A 3P1QA 3P1PA 4WRQA 3SP5A 1A38A 3T0MA 4F7RA 4FL5A 3M51A 2O02A 1QJBA 4JDDA 5LVZA 5D3FA 4N7YA 3UALA 5D2DA 5LHOA 3SMKA 3SMLA 5F74A 4Y3BA 3UX0A 3EFZA 3U9XA 2V7DA 1QJAA 4JC3A 2C74A 3UZDA 3IQUA 5BTVA 4N7GA 2B05A 5D3EA 4J6SA 2NPMA 1A37A 3UBWA 1YWTA 1YZ5A 4DHNA 2WH0A 3SMOA 4BG6A 4DHQA 1O9CA 3P1RA 2O8PA 5IQPA 3SPRA 3P1OA 5LX2A 2BQ0A 4DHPA 5LU1A 4O46A 2C1NA 4QLIA 4N84A 3RDHA 4DHRA 4DHTA 1IB1A 4HKCA 3P1NA 3SMNA 3M50A 4Y32A 4DX0A 3O8IA 5LU2A 4Y5IA 4DNKA 4ZQ0A 3NKXA 4GNTA 4E2EA 3E6YA 3SMMA 3P1SA 4IEAA 4ZDRA 2BTPA 1O9DA 4DATA 4FJ3A 5EXAA 3IQVA 2C1JA 1O9EA 4DHOA 4DHSA 2C63A 3T0LA 4IHLA 5BY9A 3MHRA 4DHUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DHM A;  5HF3 A;  1O9F A;  3AXY C;  2BR9 A;  3IQJ A;  1A4O A;  3LW1 A;  2O98 A;  3CU8 A;  2C23 A;  4FR3 A;  5EWZ A;  4DAU A;  5J31 A;  3P1Q A;  3P1P A;  4WRQ A;  3SP5 A;  1A38 A;  3T0M A;  4F7R A;  4FL5 A;  3M51 A;  2O02 A;  1QJB A;  4JDD A;  5LVZ A;  5D3F A;  4N7Y A;  3UAL A;  5D2D A;  5LHO A;  3SMK A;  3SML A;  5F74 A;  4Y3B A;  3UX0 A;  3EFZ A;  3U9X A;  2V7D A;  1QJA A;  4JC3 A;  2C74 A;  3UZD A;  3IQU A;  5BTV A;  4N7G A;  2B05 A;  5D3E A;  4J6S A;  2NPM A;  1A37 A;  3UBW A;  1YWT A;  1YZ5 A;  4DHN A;  2WH0 A;  3SMO A;  4BG6 A;  4DHQ A;  1O9C A;  3P1R A;  2O8P A;  5IQP A;  3SPR A;  3P1O A;  5LX2 A;  2BQ0 A;  4DHP A;  5LU1 A;  4O46 A;  2C1N A;  4QLI A;  4N84 A;  3RDH A;  4DHR A;  4DHT A;  1IB1 A;  4HKC A;  3P1N A;  3SMN A;  3M50 A;  4Y32 A;  4DX0 A;  3O8I A;  5LU2 A;  4Y5I A;  4DNK A;  4ZQ0 A;  3NKX A;  4GNT A;  4E2E A;  3E6Y A;  3SMM A;  3P1S A;  4IEA A;  4ZDR A;  2BTP A;  1O9D A;  4DAT A;  4FJ3 A;  5EXA A;  3IQV A;  2C1J A;  1O9E A;  4DHO A;  4DHS A;  2C63 A;  3T0L A;  4IHL A;  5BY9 A;  3MHR A;  4DHU A; 
#chains in the Genus database with same CATH topology
 4DHM A;  5HF3 A;  1O9F A;  4ARY A;  1JI6 A;  3AXY C;  2BR9 A;  3IQJ A;  1A4O A;  3LW1 A;  2O98 A;  3CU8 A;  4QX2 A;  2C23 A;  4FR3 A;  5EWZ A;  4DAU A;  5J31 A;  3P1Q A;  3P1P A;  4WRQ A;  3SP5 A;  1A38 A;  2C9K A;  4MOA A;  3T0M A;  4F7R A;  4FL5 A;  3M51 A;  2O02 A;  4D8M A;  1QJB A;  4JDD A;  5LVZ A;  5D3F A;  4N7Y A;  3UAL A;  5D2D A;  5LHO A;  3SMK A;  3SML A;  5F74 A;  4Y3B A;  3UX0 A;  3EFZ A;  3U9X A;  2V7D A;  1QJA A;  4JC3 A;  2C74 A;  4QX0 A;  3UZD A;  1URJ A;  3IQU A;  4ARX A;  5BTV A;  4N7G A;  2B05 A;  1W99 A;  1DLC A;  3EB7 A;  5D3E A;  4J6S A;  2NPM A;  1A37 A;  3UBW A;  1YWT A;  1YZ5 A;  4DHN A;  2WH0 A;  3SMO A;  4BG6 A;  4DHQ A;  1CIY A;  1O9C A;  3P1R A;  2O8P A;  5IQP A;  3SPR A;  3P1O A;  5LX2 A;  2BQ0 A;  4DHP A;  5LU1 A;  4O46 A;  2C1N A;  4QLI A;  4N84 A;  3RDH A;  4DHR A;  3I4R A;  4DHT A;  1IB1 A;  4HKC A;  3P1N A;  3SMN A;  3M50 A;  4Y32 A;  4DX0 A;  3O8I A;  5LU2 A;  4W8J A;  4Y5I A;  4DNK A;  4ZQ0 A;  3NKX A;  4GNT A;  4E2E A;  1I5P A;  3E6Y A;  3SMM A;  3CQC A;  3P1S A;  4QX1 A;  1S2X A;  4IEA A;  4ZDR A;  2BTP A;  1O9D A;  4DAT A;  4FJ3 A;  3X0U A;  5EXA A;  3IQV A;  3ZHE B;  2C1J A;  1O9E A;  4DHO A;  4DHS A;  2C63 A;  4QX3 A;  3T0L A;  3CQG A;  4IHL A;  5BY9 A;  3MHR A;  4DHU A; 
#chains in the Genus database with same CATH homology
 4DHM A;  5HF3 A;  1O9F A;  3AXY C;  2BR9 A;  3IQJ A;  1A4O A;  3LW1 A;  2O98 A;  3CU8 A;  2C23 A;  4FR3 A;  5EWZ A;  4DAU A;  5J31 A;  3P1Q A;  3P1P A;  4WRQ A;  3SP5 A;  1A38 A;  3T0M A;  4F7R A;  4FL5 A;  3M51 A;  2O02 A;  1QJB A;  4JDD A;  5LVZ A;  5D3F A;  4N7Y A;  3UAL A;  5D2D A;  5LHO A;  3SMK A;  3SML A;  5F74 A;  4Y3B A;  3UX0 A;  3EFZ A;  3U9X A;  2V7D A;  1QJA A;  4JC3 A;  2C74 A;  3UZD A;  3IQU A;  5BTV A;  4N7G A;  2B05 A;  5D3E A;  4J6S A;  2NPM A;  1A37 A;  3UBW A;  1YWT A;  1YZ5 A;  4DHN A;  2WH0 A;  3SMO A;  4BG6 A;  4DHQ A;  1O9C A;  3P1R A;  2O8P A;  5IQP A;  3SPR A;  3P1O A;  5LX2 A;  2BQ0 A;  4DHP A;  5LU1 A;  4O46 A;  2C1N A;  4QLI A;  4N84 A;  3RDH A;  4DHR A;  4DHT A;  1IB1 A;  4HKC A;  3P1N A;  3SMN A;  3M50 A;  4Y32 A;  4DX0 A;  3O8I A;  5LU2 A;  4Y5I A;  4DNK A;  4ZQ0 A;  3NKX A;  4GNT A;  4E2E A;  3E6Y A;  3SMM A;  3P1S A;  4IEA A;  4ZDR A;  2BTP A;  1O9D A;  4DAT A;  4FJ3 A;  5EXA A;  3IQV A;  2C1J A;  1O9E A;  4DHO A;  4DHS A;  2C63 A;  3T0L A;  4IHL A;  5BY9 A;  3MHR A;  4DHU A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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