5TDHG

The crystal structure of the dominant negative mutant g protein alpha(i)-1-beta-1-gamma-2 g203a/a326s
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
55
structure length
55
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Guanine nucleotide-binding protein G(i) subunit alpha-1
publication title The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 55
sequence length 55
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5tdhG00
3PVWG 2PBIA 5HE1G 2BCJG 1B9XB 3PSCG 3SN6G 5HE0G 2TRCG 4PNKG 1OMWG 1B9YB 3KRWG 1GOTG 1TBGE 1GG2G 1XHMB 3CIKG 4KFMG 3V5WG 5TDHG 3AH8G 1GP2G 5HE3G 1A0RG 5KDOG 4MK0G 5HE2G 3KRXG 3PVUG
chains in the Genus database with same CATH superfamily
2PBIA 5HE1G 2BCJG 1B9XB 3PSCG 3SN6G 5HE0G 2TRCG 4PNKG 1OMWG 1B9YB 3KRWG 1GOTG 1TBGE 1GG2G 1XHMB 3CIKG 4KFMG 3V5WG 5TDHG 3AH8G 1GP2G 1HFES 5HE3G 3PVUG 1A0RG 5KDOG 4MK0G 5HE2G 3KRXG 3PVWG 1IOJA
chains in the Genus database with same CATH topology
3PVWG 2PBIA 5HE1G 2BCJG 1B9XB 3PSCG 3SN6G 5HE0G 2TRCG 4PNKG 1OMWG 1B9YB 3KRWG 1GOTG 1TBGE 1GG2G 1XHMB 3CIKG 4KFMG 3V5WG 5TDHG 3AH8G 1GP2G 5HE3G 1A0RG 5KDOG 4MK0G 5HE2G 3KRXG 3PVUG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVW G;  2PBI A;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  3SN6 G;  5HE0 G;  2TRC G;  4PNK G;  1OMW G;  1B9Y B;  3KRW G;  1GOT G;  1TBG E;  1GG2 G;  1XHM B;  3CIK G;  4KFM G;  3V5W G;  5TDH G;  3AH8 G;  1GP2 G;  5HE3 G;  1A0R G;  5KDO G;  4MK0 G;  5HE2 G;  3KRX G;  3PVU G; 
#chains in the Genus database with same CATH topology
 2PBI A;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  3SN6 G;  5HE0 G;  2TRC G;  4PNK G;  1OMW G;  1B9Y B;  3KRW G;  1GOT G;  1TBG E;  1GG2 G;  1XHM B;  3CIK G;  4KFM G;  3V5W G;  5TDH G;  3AH8 G;  1GP2 G;  1HFE S;  5HE3 G;  3PVU G;  1A0R G;  5KDO G;  4MK0 G;  5HE2 G;  3KRX G;  3PVW G;  1IOJ A; 
#chains in the Genus database with same CATH homology
 3PVW G;  2PBI A;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  3SN6 G;  5HE0 G;  2TRC G;  4PNK G;  1OMW G;  1B9Y B;  3KRW G;  1GOT G;  1TBG E;  1GG2 G;  1XHM B;  3CIK G;  4KFM G;  3V5W G;  5TDH G;  3AH8 G;  1GP2 G;  5HE3 G;  1A0R G;  5KDO G;  4MK0 G;  5HE2 G;  3KRX G;  3PVU G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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