5TVOA

Crystal structure of trypanosoma brucei adometdc-delta26 monomer
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
270
structure length
254
Chain Sequence
SLFVMKDRVILITCGTITLLNCVPLICEAVSTVCGEVEWVSFMHKNYSFPWEHLSMAEEFKTLRSHFPPFIFGPIDSDHYFLYFHSDAQLSMTMYGLDRNQTKHWYSDKMLPTGPETAVIREATGLSEVVDDSWILHDLQYEPCGYSINAIRGSEYQTIHITPEEHCSFASYETNTCALNYSKCICGVLRVFDPERFSVIVFIDPDSAVGKSYHSGGTIGVEPEYYPNYEAHHRTVNEYTPGHWVLKVNYVKRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
pubmed doi rcsb
molecule tags Lyase
source organism Trypanosoma brucei brucei (strain 927/4 gutat10.1)
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 69
structure length 254
sequence length 270
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2016-11-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 5tvoA00
3EPAA 1MHMA 3DZ7A 3EP8A 3DZ3A 3H0WA 1I72A 1VR7A 3EPBA 1I7BA 3EP4A 3DZ5A 3EP5A 3EP3A 3H0VA 5TVOA 1TMIA 1JENA 1JL0A 2IIIA 3EP7A 3EP9A 1MSVA 3DZ4A 1I7MA 1I79A 3DZ2A 1TLUA 1I7CA 3EP6A 3DZ6A
chains in the Genus database with same CATH superfamily
3EPAA 1MHMA 3DZ7A 3EP8A 3DZ3A 3H0WA 1I72A 1VR7A 3EPBA 1I7BA 3EP4A 3DZ5A 3EP5A 3EP3A 3H0VA 5TVOA 1TMIA 1JENA 1JL0A 2IIIA 3EP7A 3EP9A 1MSVA 3DZ4A 1I7MA 1I79A 3DZ2A 1TLUA 1I7CA 3EP6A 3DZ6A
chains in the Genus database with same CATH topology
3EPAA 3EPAB 1MHMA 1MHMB 3DZ7A 3DZ7B 3EP8A 3DZ3A 1I72B 3DZ3B 3EP8B 3H0WA 3H0WB 1I72A 1VR7A 3EPBA 3EPBB 3EP4B 3DZ5B 3EP3B 1I7BA 3EP4A 1I7BB 3DZ5A 3EP3A 3EP5B 3EP5A 3H0VB 3H0VA 1TMIA 5TVOA 1JENA 5TVOB 1JENB 1JL0A 3EP7B 3EP9B 2IIIA 3EP7A 3EP9A 1MSVA 3DZ4B 1I7MB 1I79A 1I7MA 1I79B 3DZ4A 3DZ2A 1I7CB 3DZ2B 1TLUA 1I7CA 3EP6B 3EP6A 3DZ6A 3DZ6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EPA A;  1MHM A;  3DZ7 A;  3EP8 A;  3DZ3 A;  3H0W A;  1I72 A;  1VR7 A;  3EPB A;  1I7B A;  3EP4 A;  3DZ5 A;  3EP5 A;  3EP3 A;  3H0V A;  5TVO A;  1TMI A;  1JEN A;  1JL0 A;  2III A;  3EP7 A;  3EP9 A;  1MSV A;  3DZ4 A;  1I7M A;  1I79 A;  3DZ2 A;  1TLU A;  1I7C A;  3EP6 A;  3DZ6 A; 
#chains in the Genus database with same CATH topology
 3EPA A;  1MHM A;  3DZ7 A;  3EP8 A;  3DZ3 A;  3H0W A;  1I72 A;  1VR7 A;  3EPB A;  1I7B A;  3EP4 A;  3DZ5 A;  3EP5 A;  3EP3 A;  3H0V A;  5TVO A;  1TMI A;  1JEN A;  1JL0 A;  2III A;  3EP7 A;  3EP9 A;  1MSV A;  3DZ4 A;  1I7M A;  1I79 A;  3DZ2 A;  1TLU A;  1I7C A;  3EP6 A;  3DZ6 A; 
#chains in the Genus database with same CATH homology
 3EPA A;  3EPA B;  1MHM A;  1MHM B;  3DZ7 A;  3DZ7 B;  3EP8 A;  3DZ3 A;  1I72 B;  3DZ3 B;  3EP8 B;  3H0W A;  3H0W B;  1I72 A;  1VR7 A;  3EPB A;  3EPB B;  3EP4 B;  3DZ5 B;  3EP3 B;  1I7B A;  3EP4 A;  1I7B B;  3DZ5 A;  3EP3 A;  3EP5 B;  3EP5 A;  3H0V B;  3H0V A;  1TMI A;  5TVO A;  1JEN A;  5TVO B;  1JEN B;  1JL0 A;  3EP7 B;  3EP9 B;  2III A;  3EP7 A;  3EP9 A;  1MSV A;  3DZ4 B;  1I7M B;  1I79 A;  1I7M A;  1I79 B;  3DZ4 A;  3DZ2 A;  1I7C B;  3DZ2 B;  1TLU A;  1I7C A;  3EP6 B;  3EP6 A;  3DZ6 A;  3DZ6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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