5CNXA

Crystal structure of xaa-pro aminopeptidase from escherichia coli k12
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
360
structure length
360
Chain Sequence
STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords Aminopeptidase YpdF
total genus 121
structure length 360
sequence length 360
chains with identical sequence B, C
ec nomenclature ec 3.4.11.-:
pdb deposition date 2015-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5cnxA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5cnxA02
1C21A 2HOWA 2GU6A 5CDVA 3IU9A 2Q94A 2GG9A 2Q95A 5CLSA 1XGOA 4HXXA 1C24A 1YW7A 1QXYA 1KQ0A 5JFRA 1PV9A 2GTXA 4U1BA 2ADUA 3TB5A 1WBQA 1QXZA 3IL0A 4MATA 3FM3A 1YW8A 2DFIA 3Q6DA 2GGBA 2BWYA 4PV4A 1YVMA 2GA2A 4ZNGA 4FUKA 4Z7MA 5CIKA 3PN9A 2Q92A 4U6ZA 4U70A 2BWXA 4B28A 2GG3A 2BHAA 2GU5A 4OOKA 3MR1A 4U75A 3TAVA 3RVAA 4PNCA 3MX6A 4IKSA 4A6WA 1KP0A 4FO8A 2BWWA 2IW2A 1R58A 5CE6A 2GG8A 3BIQA 1XGNA 2B3LA 3BIPA 4R60A 2MATA 4S2RP 1JAWA 2EA2A 4IKUA 4U76A 2P9AA 4IDYA 1M35A 2BH3A 3D27A 1C22A 3BITA 4ZWOA 1C27A 5E5BA 1WKMA 2BHDA 1R5GA 2Q93A 1W2MA 2BHBA 3FMRA 2EA4A 4ZWUA 4EGEA 3O5VA 3PEBA 4RZYA 5CDEA 1W7VA 1Y1NA 2GZ5A 4U6CA 3I7MA 1YJ3A 3RORA 1KQ9A 2V3ZA 4S2TP 4A6VA 3L7GA 3PKAA 4JUQA 3OVKA 1YW9A 1BN5A 3FMQA 2B3HA 4U6WA 4FKCA 2BWVA 1QZYA 2Q8KA 3QOCA 1BOAA 4FLKA 5JHUA 2GG0A 1O0XA 2BWTA 5D6FA 3PKBA 4ZWPA 4IKTA 2V3XA 2NQ7A 4KM3A 2ZSGA 2B3KA 4IPAA 4U73A 4FLJA 4QR8A 3PKCA 5D6EA 2V6CA 4S01A 4IF7A 2BWSA 3CB5A 5CNXA 2GG5A 2Q96A 1QXWA 1R5HA 2EVOA 3IG4A 3MATA 4U6EA 3CTZA 1XNZA 4FLIA 2G6PA 1B59A 2OAZA 1N51A 2GGCA 5E2CA 2BN7A 2P99A 4IKRA 2BHCA 1XGSA 2OKNA 1WL6A 1WN1A 3CB6A 4U69A 3OOOA 5CDLA 1WY2A 1WL9A 3PKDA 5FCFA 3IU8A 4FO7A 1XGMA 4U6JA 2GG7A 4FLLA 1C23A 1B6AA 2BWUA 4U71A 3S6BA 2GU7A 3IU7A 1CHMA 4S00A 2GU4A 3L24A 4IU6A 2GG2A 2EVCA 5JI6A 4RGZ1 5FCHA 2P98A 4IECA 2NQ6A 4RZZA 1MATA 2EVMA 1A16A 1WLRA 3PKEA 2BB7A 2V3YA
chains in the Genus database with same CATH superfamily
1C21A 2HOWA 2GU6A 5CDVA 3IU9A 2Q94A 2GG9A 2Q95A 5CLSA 1XGOA 4HXXA 1C24A 1YW7A 1QXYA 1KQ0A 5JFRA 1PV9A 2GTXA 4U1BA 2ADUA 3TB5A 1WBQA 1QXZA 3IL0A 4MATA 3FM3A 1YW8A 2DFIA 3Q6DA 2GGBA 2BWYA 4PV4A 1YVMA 2GA2A 4ZNGA 4FUKA 4Z7MA 5CIKA 3PN9A 2Q92A 4U6ZA 4U70A 2BWXA 4B28A 2GG3A 2BHAA 2GU5A 4OOKA 3MR1A 4U75A 3TAVA 3RVAA 4PNCA 3MX6A 4IKSA 4A6WA 1KP0A 4FO8A 2BWWA 2IW2A 1R58A 5CE6A 2GG8A 3BIQA 1XGNA 2B3LA 3BIPA 4R60A 2MATA 4S2RP 1JAWA 2EA2A 4IKUA 4U76A 2P9AA 4IDYA 1M35A 2BH3A 3D27A 1C22A 3BITA 4ZWOA 1C27A 5E5BA 1WKMA 2BHDA 1R5GA 2Q93A 1W2MA 2BHBA 3FMRA 2EA4A 4ZWUA 4EGEA 3O5VA 3PEBA 4RZYA 5CDEA 1W7VA 1Y1NA 2GZ5A 4U6CA 3I7MA 1YJ3A 3RORA 1KQ9A 2V3ZA 4S2TP 4A6VA 3L7GA 3PKAA 4JUQA 3OVKA 1YW9A 1BN5A 3FMQA 2B3HA 4U6WA 4FKCA 2BWVA 1QZYA 2Q8KA 3QOCA 1BOAA 4FLKA 5JHUA 2GG0A 1O0XA 2BWTA 5D6FA 3PKBA 4ZWPA 4IKTA 2V3XA 2NQ7A 4KM3A 2ZSGA 2B3KA 4IPAA 4U73A 4FLJA 4QR8A 3PKCA 5D6EA 2V6CA 4S01A 4IF7A 2BWSA 3CB5A 5CNXA 2GG5A 2Q96A 1QXWA 1R5HA 2EVOA 3IG4A 3MATA 4U6EA 3CTZA 1XNZA 4FLIA 2G6PA 1B59A 2OAZA 1N51A 2GGCA 5E2CA 2BN7A 2P99A 4IKRA 2BHCA 1XGSA 2OKNA 1WL6A 1WN1A 3CB6A 4U69A 3OOOA 5CDLA 1WY2A 1WL9A 3PKDA 5FCFA 3IU8A 4FO7A 1XGMA 4U6JA 2GG7A 4FLLA 1C23A 1B6AA 2BWUA 4U71A 3S6BA 2GU7A 3IU7A 1CHMA 4S00A 2GU4A 3L24A 4IU6A 2GG2A 2EVCA 5JI6A 4RGZ1 5FCHA 2P98A 4IECA 2NQ6A 4RZZA 1MATA 2EVMA 1A16A 1WLRA 3PKEA 2BB7A 2V3YA
chains in the Genus database with same CATH topology
1C21A 2HOWA 2GU6A 5CDVA 3IU9A 2Q94A 2GG9A 2Q95A 5CLSA 1XGOA 4HXXA 1C24A 1YW7A 1QXYA 1KQ0A 5JFRA 1PV9A 2GTXA 4U1BA 2ADUA 3TB5A 1WBQA 1QXZA 3IL0A 4MATA 3FM3A 1YW8A 2DFIA 3Q6DA 2GGBA 2BWYA 4PV4A 1YVMA 2GA2A 4ZNGA 4FUKA 4Z7MA 5CIKA 3PN9A 2Q92A 4U6ZA 4U70A 2BWXA 4B28A 2GG3A 2BHAA 2GU5A 4OOKA 3MR1A 4U75A 3TAVA 3RVAA 4PNCA 3MX6A 4IKSA 4A6WA 1KP0A 4FO8A 2BWWA 2IW2A 1R58A 5CE6A 2GG8A 3BIQA 1XGNA 2B3LA 3BIPA 4R60A 2MATA 4S2RP 1JAWA 2EA2A 4IKUA 4U76A 2P9AA 4IDYA 1M35A 2BH3A 3D27A 1C22A 3BITA 4ZWOA 1C27A 5E5BA 1WKMA 2BHDA 1R5GA 2Q93A 1W2MA 2BHBA 3FMRA 2EA4A 4ZWUA 4EGEA 3O5VA 3PEBA 4RZYA 5CDEA 1W7VA 1Y1NA 2GZ5A 4U6CA 3I7MA 1YJ3A 3RORA 1KQ9A 2V3ZA 4S2TP 4A6VA 3L7GA 3PKAA 4JUQA 3OVKA 1YW9A 1BN5A 3FMQA 2B3HA 4U6WA 4FKCA 2BWVA 1QZYA 2Q8KA 3QOCA 1BOAA 4FLKA 5JHUA 2GG0A 1O0XA 2BWTA 5D6FA 3PKBA 4ZWPA 4IKTA 2V3XA 2NQ7A 4KM3A 2ZSGA 2B3KA 4IPAA 4U73A 4FLJA 4QR8A 3PKCA 5D6EA 2V6CA 4S01A 4IF7A 2BWSA 3CB5A 5CNXA 2GG5A 2Q96A 1QXWA 1R5HA 2EVOA 3IG4A 3MATA 4U6EA 3CTZA 1XNZA 4FLIA 2G6PA 1B59A 2OAZA 1N51A 2GGCA 5E2CA 2BN7A 2P99A 4IKRA 2BHCA 1XGSA 2OKNA 1WL6A 1WN1A 3CB6A 4U69A 3OOOA 5CDLA 1WY2A 1WL9A 3PKDA 5FCFA 3IU8A 4FO7A 1XGMA 4U6JA 2GG7A 4FLLA 1C23A 1B6AA 2BWUA 4U71A 3S6BA 2GU7A 3IU7A 1CHMA 4S00A 2GU4A 3L24A 4IU6A 2GG2A 2EVCA 5JI6A 4RGZ1 5FCHA 2P98A 4IECA 2NQ6A 4RZZA 1MATA 2EVMA 1A16A 1WLRA 3PKEA 2BB7A 2V3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C21 A;  2HOW A;  2GU6 A;  5CDV A;  3IU9 A;  2Q94 A;  2GG9 A;  2Q95 A;  5CLS A;  1XGO A;  4HXX A;  1C24 A;  1YW7 A;  1QXY A;  1KQ0 A;  5JFR A;  1PV9 A;  2GTX A;  4U1B A;  2ADU A;  3TB5 A;  1WBQ A;  1QXZ A;  3IL0 A;  4MAT A;  3FM3 A;  1YW8 A;  2DFI A;  3Q6D A;  2GGB A;  2BWY A;  4PV4 A;  1YVM A;  2GA2 A;  4ZNG A;  4FUK A;  4Z7M A;  5CIK A;  3PN9 A;  2Q92 A;  4U6Z A;  4U70 A;  2BWX A;  4B28 A;  2GG3 A;  2BHA A;  2GU5 A;  4OOK A;  3MR1 A;  4U75 A;  3TAV A;  3RVA A;  4PNC A;  3MX6 A;  4IKS A;  4A6W A;  1KP0 A;  4FO8 A;  2BWW A;  2IW2 A;  1R58 A;  5CE6 A;  2GG8 A;  3BIQ A;  1XGN A;  2B3L A;  3BIP A;  4R60 A;  2MAT A;  4S2R P;  1JAW A;  2EA2 A;  4IKU A;  4U76 A;  2P9A A;  4IDY A;  1M35 A;  2BH3 A;  3D27 A;  1C22 A;  3BIT A;  4ZWO A;  1C27 A;  5E5B A;  1WKM A;  2BHD A;  1R5G A;  2Q93 A;  1W2M A;  2BHB A;  3FMR A;  2EA4 A;  4ZWU A;  4EGE A;  3O5V A;  3PEB A;  4RZY A;  5CDE A;  1W7V A;  1Y1N A;  2GZ5 A;  4U6C A;  3I7M A;  1YJ3 A;  3ROR A;  1KQ9 A;  2V3Z A;  4S2T P;  4A6V A;  3L7G A;  3PKA A;  4JUQ A;  3OVK A;  1YW9 A;  1BN5 A;  3FMQ A;  2B3H A;  4U6W A;  4FKC A;  2BWV A;  1QZY A;  2Q8K A;  3QOC A;  1BOA A;  4FLK A;  5JHU A;  2GG0 A;  1O0X A;  2BWT A;  5D6F A;  3PKB A;  4ZWP A;  4IKT A;  2V3X A;  2NQ7 A;  4KM3 A;  2ZSG A;  2B3K A;  4IPA A;  4U73 A;  4FLJ A;  4QR8 A;  3PKC A;  5D6E A;  2V6C A;  4S01 A;  4IF7 A;  2BWS A;  3CB5 A;  5CNX A;  2GG5 A;  2Q96 A;  1QXW A;  1R5H A;  2EVO A;  3IG4 A;  3MAT A;  4U6E A;  3CTZ A;  1XNZ A;  4FLI A;  2G6P A;  1B59 A;  2OAZ A;  1N51 A;  2GGC A;  5E2C A;  2BN7 A;  2P99 A;  4IKR A;  2BHC A;  1XGS A;  2OKN A;  1WL6 A;  1WN1 A;  3CB6 A;  4U69 A;  3OOO A;  5CDL A;  1WY2 A;  1WL9 A;  3PKD A;  5FCF A;  3IU8 A;  4FO7 A;  1XGM A;  4U6J A;  2GG7 A;  4FLL A;  1C23 A;  1B6A A;  2BWU A;  4U71 A;  3S6B A;  2GU7 A;  3IU7 A;  1CHM A;  4S00 A;  2GU4 A;  3L24 A;  4IU6 A;  2GG2 A;  2EVC A;  5JI6 A;  4RGZ 1;  5FCH A;  2P98 A;  4IEC A;  2NQ6 A;  4RZZ A;  1MAT A;  2EVM A;  1A16 A;  1WLR A;  3PKE A;  2BB7 A;  2V3Y A; 
#chains in the Genus database with same CATH topology
 1C21 A;  2HOW A;  2GU6 A;  5CDV A;  3IU9 A;  2Q94 A;  2GG9 A;  2Q95 A;  5CLS A;  1XGO A;  4HXX A;  1C24 A;  1YW7 A;  1QXY A;  1KQ0 A;  5JFR A;  1PV9 A;  2GTX A;  4U1B A;  2ADU A;  3TB5 A;  1WBQ A;  1QXZ A;  3IL0 A;  4MAT A;  3FM3 A;  1YW8 A;  2DFI A;  3Q6D A;  2GGB A;  2BWY A;  4PV4 A;  1YVM A;  2GA2 A;  4ZNG A;  4FUK A;  4Z7M A;  5CIK A;  3PN9 A;  2Q92 A;  4U6Z A;  4U70 A;  2BWX A;  4B28 A;  2GG3 A;  2BHA A;  2GU5 A;  4OOK A;  3MR1 A;  4U75 A;  3TAV A;  3RVA A;  4PNC A;  3MX6 A;  4IKS A;  4A6W A;  1KP0 A;  4FO8 A;  2BWW A;  2IW2 A;  1R58 A;  5CE6 A;  2GG8 A;  3BIQ A;  1XGN A;  2B3L A;  3BIP A;  4R60 A;  2MAT A;  4S2R P;  1JAW A;  2EA2 A;  4IKU A;  4U76 A;  2P9A A;  4IDY A;  1M35 A;  2BH3 A;  3D27 A;  1C22 A;  3BIT A;  4ZWO A;  1C27 A;  5E5B A;  1WKM A;  2BHD A;  1R5G A;  2Q93 A;  1W2M A;  2BHB A;  3FMR A;  2EA4 A;  4ZWU A;  4EGE A;  3O5V A;  3PEB A;  4RZY A;  5CDE A;  1W7V A;  1Y1N A;  2GZ5 A;  4U6C A;  3I7M A;  1YJ3 A;  3ROR A;  1KQ9 A;  2V3Z A;  4S2T P;  4A6V A;  3L7G A;  3PKA A;  4JUQ A;  3OVK A;  1YW9 A;  1BN5 A;  3FMQ A;  2B3H A;  4U6W A;  4FKC A;  2BWV A;  1QZY A;  2Q8K A;  3QOC A;  1BOA A;  4FLK A;  5JHU A;  2GG0 A;  1O0X A;  2BWT A;  5D6F A;  3PKB A;  4ZWP A;  4IKT A;  2V3X A;  2NQ7 A;  4KM3 A;  2ZSG A;  2B3K A;  4IPA A;  4U73 A;  4FLJ A;  4QR8 A;  3PKC A;  5D6E A;  2V6C A;  4S01 A;  4IF7 A;  2BWS A;  3CB5 A;  5CNX A;  2GG5 A;  2Q96 A;  1QXW A;  1R5H A;  2EVO A;  3IG4 A;  3MAT A;  4U6E A;  3CTZ A;  1XNZ A;  4FLI A;  2G6P A;  1B59 A;  2OAZ A;  1N51 A;  2GGC A;  5E2C A;  2BN7 A;  2P99 A;  4IKR A;  2BHC A;  1XGS A;  2OKN A;  1WL6 A;  1WN1 A;  3CB6 A;  4U69 A;  3OOO A;  5CDL A;  1WY2 A;  1WL9 A;  3PKD A;  5FCF A;  3IU8 A;  4FO7 A;  1XGM A;  4U6J A;  2GG7 A;  4FLL A;  1C23 A;  1B6A A;  2BWU A;  4U71 A;  3S6B A;  2GU7 A;  3IU7 A;  1CHM A;  4S00 A;  2GU4 A;  3L24 A;  4IU6 A;  2GG2 A;  2EVC A;  5JI6 A;  4RGZ 1;  5FCH A;  2P98 A;  4IEC A;  2NQ6 A;  4RZZ A;  1MAT A;  2EVM A;  1A16 A;  1WLR A;  3PKE A;  2BB7 A;  2V3Y A; 
#chains in the Genus database with same CATH homology
 1C21 A;  2HOW A;  2GU6 A;  5CDV A;  3IU9 A;  2Q94 A;  2GG9 A;  2Q95 A;  5CLS A;  1XGO A;  4HXX A;  1C24 A;  1YW7 A;  1QXY A;  1KQ0 A;  5JFR A;  1PV9 A;  2GTX A;  4U1B A;  2ADU A;  3TB5 A;  1WBQ A;  1QXZ A;  3IL0 A;  4MAT A;  3FM3 A;  1YW8 A;  2DFI A;  3Q6D A;  2GGB A;  2BWY A;  4PV4 A;  1YVM A;  2GA2 A;  4ZNG A;  4FUK A;  4Z7M A;  5CIK A;  3PN9 A;  2Q92 A;  4U6Z A;  4U70 A;  2BWX A;  4B28 A;  2GG3 A;  2BHA A;  2GU5 A;  4OOK A;  3MR1 A;  4U75 A;  3TAV A;  3RVA A;  4PNC A;  3MX6 A;  4IKS A;  4A6W A;  1KP0 A;  4FO8 A;  2BWW A;  2IW2 A;  1R58 A;  5CE6 A;  2GG8 A;  3BIQ A;  1XGN A;  2B3L A;  3BIP A;  4R60 A;  2MAT A;  4S2R P;  1JAW A;  2EA2 A;  4IKU A;  4U76 A;  2P9A A;  4IDY A;  1M35 A;  2BH3 A;  3D27 A;  1C22 A;  3BIT A;  4ZWO A;  1C27 A;  5E5B A;  1WKM A;  2BHD A;  1R5G A;  2Q93 A;  1W2M A;  2BHB A;  3FMR A;  2EA4 A;  4ZWU A;  4EGE A;  3O5V A;  3PEB A;  4RZY A;  5CDE A;  1W7V A;  1Y1N A;  2GZ5 A;  4U6C A;  3I7M A;  1YJ3 A;  3ROR A;  1KQ9 A;  2V3Z A;  4S2T P;  4A6V A;  3L7G A;  3PKA A;  4JUQ A;  3OVK A;  1YW9 A;  1BN5 A;  3FMQ A;  2B3H A;  4U6W A;  4FKC A;  2BWV A;  1QZY A;  2Q8K A;  3QOC A;  1BOA A;  4FLK A;  5JHU A;  2GG0 A;  1O0X A;  2BWT A;  5D6F A;  3PKB A;  4ZWP A;  4IKT A;  2V3X A;  2NQ7 A;  4KM3 A;  2ZSG A;  2B3K A;  4IPA A;  4U73 A;  4FLJ A;  4QR8 A;  3PKC A;  5D6E A;  2V6C A;  4S01 A;  4IF7 A;  2BWS A;  3CB5 A;  5CNX A;  2GG5 A;  2Q96 A;  1QXW A;  1R5H A;  2EVO A;  3IG4 A;  3MAT A;  4U6E A;  3CTZ A;  1XNZ A;  4FLI A;  2G6P A;  1B59 A;  2OAZ A;  1N51 A;  2GGC A;  5E2C A;  2BN7 A;  2P99 A;  4IKR A;  2BHC A;  1XGS A;  2OKN A;  1WL6 A;  1WN1 A;  3CB6 A;  4U69 A;  3OOO A;  5CDL A;  1WY2 A;  1WL9 A;  3PKD A;  5FCF A;  3IU8 A;  4FO7 A;  1XGM A;  4U6J A;  2GG7 A;  4FLL A;  1C23 A;  1B6A A;  2BWU A;  4U71 A;  3S6B A;  2GU7 A;  3IU7 A;  1CHM A;  4S00 A;  2GU4 A;  3L24 A;  4IU6 A;  2GG2 A;  2EVC A;  5JI6 A;  4RGZ 1;  5FCH A;  2P98 A;  4IEC A;  2NQ6 A;  4RZZ A;  1MAT A;  2EVM A;  1A16 A;  1WLR A;  3PKE A;  2BB7 A;  2V3Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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