5D3WA

Crystal structure of the p-rex1 ph domain with sulfate bound
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus 45
structure length 151
sequence length 166
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3wA00
4DBBA 3KY9A 2P0HA 1KI1B 1X86A 1X11A 3D8FA 4EJNA 5C79A 2ADZA 4PNKA 4HB2B 3ODWA 1UPRA 2EMTA 1KZGA 4ZRIA 3ULBA 3F0WA 2LG1A 2YT0A 3PEGA 2YVCA 3AU5A 2Y8GA 1ISNA 2R09A 1DYNA 3LJUX 5CLLB 1MIZB 1AQCA 1OQNA 1W1HA 2YT1A 2Y8FA 3PG7A 2RUKB 4K2PA 3MDBC 2R0DA 3DXCA 1GC7A 4KHBB 2Q13A 2LOXA 1QC6A 1ZM0A 4BBKA 5C16A 1V88A 1EAZA 3A8PA 2DN6A 2DLWA 2RSGA 5DHAB 2CY4A 4ZRJA 1XX0A 3CIKA 2K2JA 4DX90 4KHAA 5J3QA 2LKOA 2D4QA 1E5WA 5DHFB 3WA0A 4EKUA 1ZC4B 4HAZB 5J3TA 4KAXB 3FEHA 2I1JA 2D9WA 2HE7A 2OQBA 2H7DA 1BAKA 1J0WA 1WVHA 2V76A 2QKMA 2ELBA 2FJLA 2L1CA 1P3RA 2YF0A 3TVVA 4IAPA 1DROA 1H10A 4GZUA 1DBHA 2VSZA 3KRXA 5LONB 1H4RA 3AJ4A 2H7EA 5GOWB 2EMSA 1SGHA 2COAA 2VKIA 1I7AA 2D10A 4WVFB 4GXBA 2W2XC 1U5DA 1TQZA 1WG7A 3KZ1A 1PLSA 1EF1A 1K5GB 3ZDTA 1EVHA 4K2OA 1XODA 2PZ1A 1Y5OA 2LYDA 1DDMA 3TCAA 4GN1A 1IRSA 2E2XA 3G9WA 1U5GA 2COFA 4F7HA 2YS1A 5D3WA 2J0MA 4TYZA 3TW1A 3VIAA 2I5FA 3T06A 4Y94A 5DH9B 1OY2A 2Y7BA 4CHMA 1MK7B 1N3HA 2RVBB 2X18A 1OMWA 3NSUA 2D9ZA 3PZDA 5LOPB 2XQNM 2ROVA 2DFKA 1MKEA 3TFMA 2Z0PA 2GS0A 2D9YA 2VRWB 1TXDA 1GC6A 4A5KA 5HE1A 4IOYX 2DKQA 2HTHB 5DIFB 2YS5A 4GMXB 2G35A 1J19A 1Q67A 2D9XA 1FOEA 5L81A 4MK0A 3DXDA 3KSYA 5FI1A 5FI0A 2ELAA 3TO1A 1XR0B 1I2HA 4HB4B 4KVGB 2AEHA 1RJ2A 2ROZB 4L6EA 4A6FB 1FHXA 1X1GA 5D3YA 1V5UA 4DX8A 4GMVA 1Y19B 3PVLA 1K5DB 4WSFA 3BINA 1TJ6A 2MDXA 2P0FA 1M7RA 3D8DA 1B55A 1W1GA 2GJYA 3SV1A 4NY0A 1EGXA 2CY5A 1V89A 1PMSA 1FB8A 2CODA 4HAYB 3ZVRA 4F7GA 5C6RA 1ZSQA 2COCA 4MY6A 2DKPA 1U29A 3ODOA 2IFSA 1XCGA 4HB3B 2W2XD 4MT7A 5KCVA 4GPTB 2GCLA 4WJ7A 3X23A 1ZC3B 5DI9B 3O96A 2YSZA 1FHOA 3A8QA 3P6AA 4TKNA 1WGUA 2MWNB 1UNQA 1M7EA 2NZ8B 1V5MA 1AWEA 1W1DA 3ULCA 4EMOA 2UZSA 1FHWA 5HE0A 1U5EA 5EFXA 2CAYA 3WYFB 3HW2B 4YL8A 1UPQA 1UNPA 1WGQA 2N23A 2KGXB 4HAXB 1XKEA 3DXEA 4ZRKA 3VOQA 2K00A 1MIXA 4B6HA 1FAOA 2EJ8A 3RCPA 4HATB 2DHKA 2Z0OA 1FGZA 2JP2A 3PP2A 3KRWA 3P7ZA 5D3XA 3HK0A 3SYXA 5HE2A 4XWXA 4IFSA 1WI1A 3PVUA 1NTYA 1RRPB 2EC1A 2CRFA 1GG3A 2N0YA 1Z87A 1LW3A 1DDVA 2RGNB 2K2UA 1SHCA 1XD4A 3F5RA 2YRYA 1PFJA 4K81A 1WJMA 2MKRA 1MK9B 4NSWA 4Z2NA 2KUPA 2DYQA 3PSCA 3QIJA 5C5BB 4DXAB 1X1FA 2LULA 3MPXA 1V61A 5JHGA 3FM8C 3SNHA 1LB1A 2P0DA 2J59M 2DTCA 3CXBB 3UZTA 4Z2MB 5KQ4A 5JP4A 3QWMA 1BTKA 1U5FA 1UNRA 2KCJA 2Z0QA 4P7IA 5D3VA 2DHJA 4CHJA 2AL6A 2I5CA 2J0JA 5JHHA 2GCJA 4YONA 2DX1A 4HAWB 1MPHA 4A6HA 4CYEA 4HDOA 2M14A 1BTNA 4A6KA 2QKLA 3GYPA 3IVFA 2D2QA 2UVMA 5J3YA 4HAVB 1WJ1A 2RNRB 2BCJA 2W2WA 3GYOA 3HQCA 1UEFA 4HAUB 2DA0A 2P8VA 2ZPYA 2I1KA 5D27A 1P6SA 4K17A 3SO6A 2L2IA 3ODXA 2OTXA 3U7DA 4C0AA 1NTVA 3A98B 2RLOA 5JLJB 2D11A 3QBVB 2J0KA 5HE3A 3M1IB 3SUZA 3V5WA 3N7CA 1DDWA 4D0NB 1X05A 2D9VA 1QQGA 3BJIA 3AU4A 5KQ1A 2YS3A 4PQ0A 2DHIA 2UZRA 1U2BA 1BWNA 2M38A 1NI2A 2MFQA 4H8SA 1KZ7A 1P5TA 3PVWA 2LOZA 2DX5A 2DYNA 4HHVA 3ML4A 1MAIA 3FSSA 1U27A 4KHOA 4HDQA 3OANA 3U8ZA 2NMBA 3D8EA 2IYBA 1V5PA 4F7UP 5CLQB 5C5BA 1NU2A 4A6FA 1ZVRA 1FGYA 4HB0B
chains in the Genus database with same CATH superfamily
4DBBA 3KY9A 2P0HA 1KI1B 1X86A 1X11A 3D8FA 4EJNA 4HSIA 5C79A 2ADZA 4PNKA 4HB2B 3ODWA 1UPRA 2EMTA 2K8EA 1KZGA 4ZRIA 3ULBA 3F0WA 2LG1A 2YT0A 3PEGA 2YVCA 3AU5A 2Y8GA 1ISNA 2R09A 1DYNA 3LJUX 5CLLB 1MIZB 1AQCA 1OQNA 1W1HA 2YT1A 2Y8FA 3PG7A 2RUKB 4K2PA 3MDBC 2R0DA 3DXCA 1GC7A 4KHBB 2Q13A 2LOXA 1QC6A 1ZM0A 4BBKA 5C16A 1V88A 2Z59A 1EAZA 3A8PA 2DN6A 2R2YA 2DLWA 2RSGA 4QXAB 5DHAB 2CY4A 4ZRJA 1XX0A 3CIKA 2K2JA 4DX90 4KHAA 5J3QA 2LKOA 2D4QA 5I2MA 1E5WA 5DHFB 3WA0A 4EKUA 1ZC4B 4HAZB 5J3TA 4KAXB 3FEHA 2I1JA 2D9WA 4L1RA 2HE7A 2OQBA 2H7DA 1BAKA 1J0WA 1WVHA 2V76A 2QKMA 3NW8A 2ELBA 2FJLA 2L1CA 1P3RA 2YF0A 3TVVA 4IAPA 1DROA 1H10A 4GZUA 1DBHA 2VSZA 3KRXA 5LONB 1H4RA 3AJ4A 2H7EA 5GOWB 2EMSA 1SGHA 2COAA 2VKIA 1I7AA 2D10A 4WVFB 4GXBA 2Z4DA 2W2XC 1U5DA 1TQZA 1WG7A 3KZ1A 1PLSA 4OT1A 1EF1A 1K5GB 3ZDTA 1EVHA 4K2OA 1XODA 2PZ1A 1Y5OA 2LYDA 1DDMA 3TCAA 4GN1A 1IRSA 2E2XA 3NWDA 3G9WA 1U5GA 4KHBA 2COFA 4CSQA 4F7HA 2YS1A 5D3WA 2J0MA 4TYZA 3TW1A 3VIAA 2I5FA 3T06A 4Y94A 5DH9B 1OY2A 2Y7BA 4CHMA 1MK7B 1N3HA 2RVBB 2X18A 1OMWA 3NSUA 2D9ZA 3PZDA 5LOPB 2XQNM 2RRFA 2ROVA 2DFKA 1MKEA 3TFMA 2Z0PA 2GS0A 2D9YA 2VRWB 1TXDA 1GC6A 4A5KA 5HE1A 2KUQA 4IOYX 2DKQA 2HTHB 5DIFB 2YS5A 4GMXB 2G35A 1J19A 1Q67A 2D9XA 1FOEA 5L81A 4MK0A 3DXDA 3KSYA 5FI1A 5FI0A 2ELAA 3TO1A 1XR0B 1I2HA 4HB4B 4KVGB 2AEHA 1RJ2A 2ROZB 4L6EA 4A6FB 1FHXA 1X1GA 5D3YA 4QJ5B 2NBVA 1V5UA 4DX8A 4GMVA 1Y19B 3PVLA 1K5DB 4WSFA 3BINA 1TJ6A 2MDXA 2P0FA 1M7RA 3D8DA 1B55A 1W1GA 2GJYA 3SV1A 4NY0A 1EGXA 2CY5A 1V89A 1PMSA 2GUMA 1FB8A 2CODA 3U12A 4HAYB 3ZVRA 4F7GA 5C6RA 1ZSQA 2COCA 4MY6A 2DKPA 1U29A 3ODOA 2IFSA 1XCGA 4HB3B 2W2XD 4MT7A 5KCVA 4GPTB 2GCLA 4WJ7A 3X23A 1ZC3B 5DI9B 3O96A 2YSZA 1FHOA 3A8QA 2Z13A 3P6AA 4GNKB 4TKNA 1WGUA 2MWNB 1UNQA 1M7EA 2NZ8B 1T77A 1V5MA 1AWEA 1W1DA 3ULCA 4EMOA 2UZSA 1FHWA 5HE0A 1U5EA 5EFXA 2CAYA 3WYFB 2KIEA 3HW2B 4YL8A 1UPQA 1UNPA 2K49A 1WGQA 2N23A 2KGXB 4HAXB 1XKEA 3DXEA 4ZRKA 5I2SA 3VOQA 3DCXA 2K00A 1MIXA 4B6HA 1FAOA 2EJ8A 3RCPA 4HATB 2DHKA 2Z0OA 1FGZA 2JP2A 3PP2A 3KRWA 3P7ZA 5D3XA 3HK0A 2KR0A 3SYXA 5HE2A 4XWXA 4IFSA 1WI1A 3PVUA 3OHMB 1NTYA 1RRPB 2EC1A 2CRFA 1GG3A 2N0YA 1Z87A 1LW3A 3B77A 1DDVA 2RGNB 5IRSA 2K2UA 1SHCA 1XD4A 3F5RA 2YRYA 1PFJA 4K81A 1WJMA 2MKRA 1MK9B 4NSWA 4Z2NA 2KUPA 4GOUA 2DYQA 3PSCA 3QIJA 5C5BB 4DXAB 1X1FA 2LULA 3MPXA 1V61A 5JHGA 3FM8C 3SNHA 1LB1A 2P0DA 2J59M 2DTCA 3CXBB 3UZTA 4Z2MB 5KQ4A 5LG4B 5JP4A 3QWMA 1BTKA 1U5FA 1UNRA 2KCJA 2Z0QA 4P7IA 5D3VA 2Z14A 2DHJA 2YT2A 2AL6A 2I5CA 2J0JA 4CHJA 5JHHA 2GCJA 4YONA 3NWFA 2KIGA 2DX1A 3HIEA 4HAWB 1MPHA 4A6HA 4CYEA 4HDOA 2M14A 1BTNA 4A6KA 2QKLA 3GYPA 4DIXA 3HSAA 3IVFA 2D2QA 2UVMA 5J3YA 4HAVB 1WJ1A 2RNRB 2BCJA 2W2WA 3GYOA 4QJ3B 3HQCA 1UEFA 4HAUB 2DA0A 2P8VA 2ZPYA 4OSNA 2I1KA 5D27A 1P6SA 4K17A 3SO6A 2L2IA 3ODXA 2OTXA 1ZYIA 3U7DA 4C0AA 1NTVA 3A98B 2RLOA 5JLJB 2D11A 3QBVB 2J0KA 5HE3A 3M1IB 3SUZA 3V5WA 3N7CA 1DDWA 4D0NB 1X05A 2D9VA 1QQGA 3BJIA 3AU4A 3FVCA 5KQ1A 2YS3A 4PQ0A 2DHIA 2UZRA 1U2BA 1BWNA 2M38A 1NI2A 2MFQA 4H8SA 1KZ7A 1P5TA 3PVWA 2LOZA 2ZKMX 2DX5A 2DYNA 4QJ4B 1MI1A 4HHVA 3A58A 3ML4A 1MAIA 3FSSA 1U27A 4KHOA 4HDQA 3OANA 3U8ZA 2NMBA 3D8EA 2IYBA 1V5PA 3NWAA 4F7UP 5CLQB 5C5BA 1NU2A 2FJUB 4D6WA 4A6FA 5M4YB 1ZVRA 1FGYA 4HB0B
chains in the Genus database with same CATH topology
4DBBA 3KY9A 2P0HA 1KI1B 1X86A 1X11A 3D8FA 4EJNA 5C79A 2ADZA 4PNKA 4HB2B 3ODWA 1UPRA 2EMTA 1KZGA 4ZRIA 3ULBA 3F0WA 2LG1A 2YT0A 3PEGA 2YVCA 3AU5A 2Y8GA 1ISNA 2R09A 1DYNA 3LJUX 5CLLB 1MIZB 1AQCA 1OQNA 1W1HA 2YT1A 2Y8FA 3PG7A 2RUKB 4K2PA 3MDBC 2R0DA 3DXCA 1GC7A 4KHBB 2Q13A 2LOXA 1QC6A 1ZM0A 4BBKA 5C16A 1V88A 1EAZA 3A8PA 2DN6A 2DLWA 2RSGA 5DHAB 2CY4A 4ZRJA 1XX0A 3CIKA 2K2JA 4DX90 4KHAA 5J3QA 2LKOA 2D4QA 1E5WA 5DHFB 3WA0A 4EKUA 1ZC4B 4HAZB 5J3TA 4KAXB 3FEHA 2I1JA 2D9WA 2HE7A 2OQBA 2H7DA 1BAKA 1J0WA 1WVHA 2V76A 2QKMA 2ELBA 2FJLA 2L1CA 1P3RA 2YF0A 3TVVA 4IAPA 1DROA 1H10A 4GZUA 1DBHA 2VSZA 3KRXA 5LONB 1H4RA 3AJ4A 2H7EA 5GOWB 2EMSA 1SGHA 2COAA 2VKIA 1I7AA 2D10A 4WVFB 4GXBA 2W2XC 1U5DA 1TQZA 1WG7A 3KZ1A 1PLSA 1EF1A 1K5GB 3ZDTA 1EVHA 4K2OA 1XODA 2PZ1A 1Y5OA 2LYDA 1DDMA 3TCAA 4GN1A 1IRSA 2E2XA 3G9WA 1U5GA 2COFA 4F7HA 2YS1A 5D3WA 2J0MA 4TYZA 3TW1A 3VIAA 2I5FA 3T06A 4Y94A 5DH9B 1OY2A 2Y7BA 4CHMA 1MK7B 1N3HA 2RVBB 2X18A 1OMWA 3NSUA 2D9ZA 3PZDA 5LOPB 2XQNM 2ROVA 2DFKA 1MKEA 3TFMA 2Z0PA 2GS0A 2D9YA 2VRWB 1TXDA 1GC6A 4A5KA 5HE1A 4IOYX 2DKQA 2HTHB 5DIFB 2YS5A 4GMXB 2G35A 1J19A 1Q67A 2D9XA 1FOEA 5L81A 4MK0A 3DXDA 3KSYA 5FI1A 5FI0A 2ELAA 3TO1A 1XR0B 1I2HA 4HB4B 4KVGB 2AEHA 1RJ2A 2ROZB 4L6EA 4A6FB 1FHXA 1X1GA 5D3YA 1V5UA 4DX8A 4GMVA 1Y19B 3PVLA 1K5DB 4WSFA 3BINA 1TJ6A 2MDXA 2P0FA 1M7RA 3D8DA 1B55A 1W1GA 2GJYA 3SV1A 4NY0A 1EGXA 2CY5A 1V89A 1PMSA 1FB8A 2CODA 4HAYB 3ZVRA 4F7GA 5C6RA 1ZSQA 2COCA 4MY6A 2DKPA 1U29A 3ODOA 2IFSA 1XCGA 4HB3B 2W2XD 4MT7A 5KCVA 4GPTB 2GCLA 4WJ7A 3X23A 1ZC3B 5DI9B 3O96A 2YSZA 1FHOA 3A8QA 3P6AA 4TKNA 1WGUA 2MWNB 1UNQA 1M7EA 2NZ8B 1V5MA 1AWEA 1W1DA 3ULCA 4EMOA 2UZSA 1FHWA 5HE0A 1U5EA 5EFXA 2CAYA 3WYFB 3HW2B 4YL8A 1UPQA 1UNPA 1WGQA 2N23A 2KGXB 4HAXB 1XKEA 3DXEA 4ZRKA 3VOQA 2K00A 1MIXA 4B6HA 1FAOA 2EJ8A 3RCPA 4HATB 2DHKA 2Z0OA 1FGZA 2JP2A 3PP2A 3KRWA 3P7ZA 5D3XA 3HK0A 3SYXA 5HE2A 4XWXA 4IFSA 1WI1A 3PVUA 1NTYA 1RRPB 2EC1A 2CRFA 1GG3A 2N0YA 1Z87A 1LW3A 1DDVA 2RGNB 2K2UA 1SHCA 1XD4A 3F5RA 2YRYA 1PFJA 4K81A 1WJMA 2MKRA 1MK9B 4NSWA 4Z2NA 2KUPA 2DYQA 3PSCA 3QIJA 5C5BB 4DXAB 1X1FA 2LULA 3MPXA 1V61A 5JHGA 3FM8C 3SNHA 1LB1A 2P0DA 2J59M 2DTCA 3CXBB 3UZTA 4Z2MB 5KQ4A 5JP4A 3QWMA 1BTKA 1U5FA 1UNRA 2KCJA 2Z0QA 4P7IA 5D3VA 2DHJA 4CHJA 2AL6A 2I5CA 2J0JA 5JHHA 2GCJA 4YONA 2DX1A 4HAWB 1MPHA 4A6HA 4CYEA 4HDOA 2M14A 1BTNA 4A6KA 2QKLA 3GYPA 3IVFA 2D2QA 2UVMA 5J3YA 4HAVB 1WJ1A 2RNRB 2BCJA 2W2WA 3GYOA 3HQCA 1UEFA 4HAUB 2DA0A 2P8VA 2ZPYA 2I1KA 5D27A 1P6SA 4K17A 3SO6A 2L2IA 3ODXA 2OTXA 3U7DA 4C0AA 1NTVA 3A98B 2RLOA 5JLJB 2D11A 3QBVB 2J0KA 5HE3A 3M1IB 3SUZA 3V5WA 3N7CA 1DDWA 4D0NB 1X05A 2D9VA 1QQGA 3BJIA 3AU4A 5KQ1A 2YS3A 4PQ0A 2DHIA 2UZRA 1U2BA 1BWNA 2M38A 1NI2A 2MFQA 4H8SA 1KZ7A 1P5TA 3PVWA 2LOZA 2DX5A 2DYNA 4HHVA 3ML4A 1MAIA 3FSSA 1U27A 4KHOA 4HDQA 3OANA 3U8ZA 2NMBA 3D8EA 2IYBA 1V5PA 4F7UP 5CLQB 5C5BA 1NU2A 4A6FA 1ZVRA 1FGYA 4HB0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DBB A;  3KY9 A;  2P0H A;  1KI1 B;  1X86 A;  1X11 A;  3D8F A;  4EJN A;  5C79 A;  2ADZ A;  4PNK A;  4HB2 B;  3ODW A;  1UPR A;  2EMT A;  1KZG A;  4ZRI A;  3ULB A;  3F0W A;  2LG1 A;  2YT0 A;  3PEG A;  2YVC A;  3AU5 A;  2Y8G A;  1ISN A;  2R09 A;  1DYN A;  3LJU X;  5CLL B;  1MIZ B;  1AQC A;  1OQN A;  1W1H A;  2YT1 A;  2Y8F A;  3PG7 A;  2RUK B;  4K2P A;  3MDB C;  2R0D A;  3DXC A;  1GC7 A;  4KHB B;  2Q13 A;  2LOX A;  1QC6 A;  1ZM0 A;  4BBK A;  5C16 A;  1V88 A;  1EAZ A;  3A8P A;  2DN6 A;  2DLW A;  2RSG A;  5DHA B;  2CY4 A;  4ZRJ A;  1XX0 A;  3CIK A;  2K2J A;  4DX9 0;  4KHA A;  5J3Q A;  2LKO A;  2D4Q A;  1E5W A;  5DHF B;  3WA0 A;  4EKU A;  1ZC4 B;  4HAZ B;  5J3T A;  4KAX B;  3FEH A;  2I1J A;  2D9W A;  2HE7 A;  2OQB A;  2H7D A;  1BAK A;  1J0W A;  1WVH A;  2V76 A;  2QKM A;  2ELB A;  2FJL A;  2L1C A;  1P3R A;  2YF0 A;  3TVV A;  4IAP A;  1DRO A;  1H10 A;  4GZU A;  1DBH A;  2VSZ A;  3KRX A;  5LON B;  1H4R A;  3AJ4 A;  2H7E A;  5GOW B;  2EMS A;  1SGH A;  2COA A;  2VKI A;  1I7A A;  2D10 A;  4WVF B;  4GXB A;  2W2X C;  1U5D A;  1TQZ A;  1WG7 A;  3KZ1 A;  1PLS A;  1EF1 A;  1K5G B;  3ZDT A;  1EVH A;  4K2O A;  1XOD A;  2PZ1 A;  1Y5O A;  2LYD A;  1DDM A;  3TCA A;  4GN1 A;  1IRS A;  2E2X A;  3G9W A;  1U5G A;  2COF A;  4F7H A;  2YS1 A;  5D3W A;  2J0M A;  4TYZ A;  3TW1 A;  3VIA A;  2I5F A;  3T06 A;  4Y94 A;  5DH9 B;  1OY2 A;  2Y7B A;  4CHM A;  1MK7 B;  1N3H A;  2RVB B;  2X18 A;  1OMW A;  3NSU A;  2D9Z A;  3PZD A;  5LOP B;  2XQN M;  2ROV A;  2DFK A;  1MKE A;  3TFM A;  2Z0P A;  2GS0 A;  2D9Y A;  2VRW B;  1TXD A;  1GC6 A;  4A5K A;  5HE1 A;  4IOY X;  2DKQ A;  2HTH B;  5DIF B;  2YS5 A;  4GMX B;  2G35 A;  1J19 A;  1Q67 A;  2D9X A;  1FOE A;  5L81 A;  4MK0 A;  3DXD A;  3KSY A;  5FI1 A;  5FI0 A;  2ELA A;  3TO1 A;  1XR0 B;  1I2H A;  4HB4 B;  4KVG B;  2AEH A;  1RJ2 A;  2ROZ B;  4L6E A;  4A6F B;  1FHX A;  1X1G A;  5D3Y A;  1V5U A;  4DX8 A;  4GMV A;  1Y19 B;  3PVL A;  1K5D B;  4WSF A;  3BIN A;  1TJ6 A;  2MDX A;  2P0F A;  1M7R A;  3D8D A;  1B55 A;  1W1G A;  2GJY A;  3SV1 A;  4NY0 A;  1EGX A;  2CY5 A;  1V89 A;  1PMS A;  1FB8 A;  2COD A;  4HAY B;  3ZVR A;  4F7G A;  5C6R A;  1ZSQ A;  2COC A;  4MY6 A;  2DKP A;  1U29 A;  3ODO A;  2IFS A;  1XCG A;  4HB3 B;  2W2X D;  4MT7 A;  5KCV A;  4GPT B;  2GCL A;  4WJ7 A;  3X23 A;  1ZC3 B;  5DI9 B;  3O96 A;  2YSZ A;  1FHO A;  3A8Q A;  3P6A A;  4TKN A;  1WGU A;  2MWN B;  1UNQ A;  1M7E A;  2NZ8 B;  1V5M A;  1AWE A;  1W1D A;  3ULC A;  4EMO A;  2UZS A;  1FHW A;  5HE0 A;  1U5E A;  5EFX A;  2CAY A;  3WYF B;  3HW2 B;  4YL8 A;  1UPQ A;  1UNP A;  1WGQ A;  2N23 A;  2KGX B;  4HAX B;  1XKE A;  3DXE A;  4ZRK A;  3VOQ A;  2K00 A;  1MIX A;  4B6H A;  1FAO A;  2EJ8 A;  3RCP A;  4HAT B;  2DHK A;  2Z0O A;  1FGZ A;  2JP2 A;  3PP2 A;  3KRW A;  3P7Z A;  5D3X A;  3HK0 A;  3SYX A;  5HE2 A;  4XWX A;  4IFS A;  1WI1 A;  3PVU A;  1NTY A;  1RRP B;  2EC1 A;  2CRF A;  1GG3 A;  2N0Y A;  1Z87 A;  1LW3 A;  1DDV A;  2RGN B;  2K2U A;  1SHC A;  1XD4 A;  3F5R A;  2YRY A;  1PFJ A;  4K81 A;  1WJM A;  2MKR A;  1MK9 B;  4NSW A;  4Z2N A;  2KUP A;  2DYQ A;  3PSC A;  3QIJ A;  5C5B B;  4DXA B;  1X1F A;  2LUL A;  3MPX A;  1V61 A;  5JHG A;  3FM8 C;  3SNH A;  1LB1 A;  2P0D A;  2J59 M;  2DTC A;  3CXB B;  3UZT A;  4Z2M B;  5KQ4 A;  5JP4 A;  3QWM A;  1BTK A;  1U5F A;  1UNR A;  2KCJ A;  2Z0Q A;  4P7I A;  5D3V A;  2DHJ A;  4CHJ A;  2AL6 A;  2I5C A;  2J0J A;  5JHH A;  2GCJ A;  4YON A;  2DX1 A;  4HAW B;  1MPH A;  4A6H A;  4CYE A;  4HDO A;  2M14 A;  1BTN A;  4A6K A;  2QKL A;  3GYP A;  3IVF A;  2D2Q A;  2UVM A;  5J3Y A;  4HAV B;  1WJ1 A;  2RNR B;  2BCJ A;  2W2W A;  3GYO A;  3HQC A;  1UEF A;  4HAU B;  2DA0 A;  2P8V A;  2ZPY A;  2I1K A;  5D27 A;  1P6S A;  4K17 A;  3SO6 A;  2L2I A;  3ODX A;  2OTX A;  3U7D A;  4C0A A;  1NTV A;  3A98 B;  2RLO A;  5JLJ B;  2D11 A;  3QBV B;  2J0K A;  5HE3 A;  3M1I B;  3SUZ A;  3V5W A;  3N7C A;  1DDW A;  4D0N B;  1X05 A;  2D9V A;  1QQG A;  3BJI A;  3AU4 A;  5KQ1 A;  2YS3 A;  4PQ0 A;  2DHI A;  2UZR A;  1U2B A;  1BWN A;  2M38 A;  1NI2 A;  2MFQ A;  4H8S A;  1KZ7 A;  1P5T A;  3PVW A;  2LOZ A;  2DX5 A;  2DYN A;  4HHV A;  3ML4 A;  1MAI A;  3FSS A;  1U27 A;  4KHO A;  4HDQ A;  3OAN A;  3U8Z A;  2NMB A;  3D8E A;  2IYB A;  1V5P A;  4F7U P;  5CLQ B;  5C5B A;  1NU2 A;  4A6F A;  1ZVR A;  1FGY A;  4HB0 B; 
#chains in the Genus database with same CATH topology
 4DBB A;  3KY9 A;  2P0H A;  1KI1 B;  1X86 A;  1X11 A;  3D8F A;  4EJN A;  4HSI A;  5C79 A;  2ADZ A;  4PNK A;  4HB2 B;  3ODW A;  1UPR A;  2EMT A;  2K8E A;  1KZG A;  4ZRI A;  3ULB A;  3F0W A;  2LG1 A;  2YT0 A;  3PEG A;  2YVC A;  3AU5 A;  2Y8G A;  1ISN A;  2R09 A;  1DYN A;  3LJU X;  5CLL B;  1MIZ B;  1AQC A;  1OQN A;  1W1H A;  2YT1 A;  2Y8F A;  3PG7 A;  2RUK B;  4K2P A;  3MDB C;  2R0D A;  3DXC A;  1GC7 A;  4KHB B;  2Q13 A;  2LOX A;  1QC6 A;  1ZM0 A;  4BBK A;  5C16 A;  1V88 A;  2Z59 A;  1EAZ A;  3A8P A;  2DN6 A;  2R2Y A;  2DLW A;  2RSG A;  4QXA B;  5DHA B;  2CY4 A;  4ZRJ A;  1XX0 A;  3CIK A;  2K2J A;  4DX9 0;  4KHA A;  5J3Q A;  2LKO A;  2D4Q A;  5I2M A;  1E5W A;  5DHF B;  3WA0 A;  4EKU A;  1ZC4 B;  4HAZ B;  5J3T A;  4KAX B;  3FEH A;  2I1J A;  2D9W A;  4L1R A;  2HE7 A;  2OQB A;  2H7D A;  1BAK A;  1J0W A;  1WVH A;  2V76 A;  2QKM A;  3NW8 A;  2ELB A;  2FJL A;  2L1C A;  1P3R A;  2YF0 A;  3TVV A;  4IAP A;  1DRO A;  1H10 A;  4GZU A;  1DBH A;  2VSZ A;  3KRX A;  5LON B;  1H4R A;  3AJ4 A;  2H7E A;  5GOW B;  2EMS A;  1SGH A;  2COA A;  2VKI A;  1I7A A;  2D10 A;  4WVF B;  4GXB A;  2Z4D A;  2W2X C;  1U5D A;  1TQZ A;  1WG7 A;  3KZ1 A;  1PLS A;  4OT1 A;  1EF1 A;  1K5G B;  3ZDT A;  1EVH A;  4K2O A;  1XOD A;  2PZ1 A;  1Y5O A;  2LYD A;  1DDM A;  3TCA A;  4GN1 A;  1IRS A;  2E2X A;  3NWD A;  3G9W A;  1U5G A;  4KHB A;  2COF A;  4CSQ A;  4F7H A;  2YS1 A;  5D3W A;  2J0M A;  4TYZ A;  3TW1 A;  3VIA A;  2I5F A;  3T06 A;  4Y94 A;  5DH9 B;  1OY2 A;  2Y7B A;  4CHM A;  1MK7 B;  1N3H A;  2RVB B;  2X18 A;  1OMW A;  3NSU A;  2D9Z A;  3PZD A;  5LOP B;  2XQN M;  2RRF A;  2ROV A;  2DFK A;  1MKE A;  3TFM A;  2Z0P A;  2GS0 A;  2D9Y A;  2VRW B;  1TXD A;  1GC6 A;  4A5K A;  5HE1 A;  2KUQ A;  4IOY X;  2DKQ A;  2HTH B;  5DIF B;  2YS5 A;  4GMX B;  2G35 A;  1J19 A;  1Q67 A;  2D9X A;  1FOE A;  5L81 A;  4MK0 A;  3DXD A;  3KSY A;  5FI1 A;  5FI0 A;  2ELA A;  3TO1 A;  1XR0 B;  1I2H A;  4HB4 B;  4KVG B;  2AEH A;  1RJ2 A;  2ROZ B;  4L6E A;  4A6F B;  1FHX A;  1X1G A;  5D3Y A;  4QJ5 B;  2NBV A;  1V5U A;  4DX8 A;  4GMV A;  1Y19 B;  3PVL A;  1K5D B;  4WSF A;  3BIN A;  1TJ6 A;  2MDX A;  2P0F A;  1M7R A;  3D8D A;  1B55 A;  1W1G A;  2GJY A;  3SV1 A;  4NY0 A;  1EGX A;  2CY5 A;  1V89 A;  1PMS A;  2GUM A;  1FB8 A;  2COD A;  3U12 A;  4HAY B;  3ZVR A;  4F7G A;  5C6R A;  1ZSQ A;  2COC A;  4MY6 A;  2DKP A;  1U29 A;  3ODO A;  2IFS A;  1XCG A;  4HB3 B;  2W2X D;  4MT7 A;  5KCV A;  4GPT B;  2GCL A;  4WJ7 A;  3X23 A;  1ZC3 B;  5DI9 B;  3O96 A;  2YSZ A;  1FHO A;  3A8Q A;  2Z13 A;  3P6A A;  4GNK B;  4TKN A;  1WGU A;  2MWN B;  1UNQ A;  1M7E A;  2NZ8 B;  1T77 A;  1V5M A;  1AWE A;  1W1D A;  3ULC A;  4EMO A;  2UZS A;  1FHW A;  5HE0 A;  1U5E A;  5EFX A;  2CAY A;  3WYF B;  2KIE A;  3HW2 B;  4YL8 A;  1UPQ A;  1UNP A;  2K49 A;  1WGQ A;  2N23 A;  2KGX B;  4HAX B;  1XKE A;  3DXE A;  4ZRK A;  5I2S A;  3VOQ A;  3DCX A;  2K00 A;  1MIX A;  4B6H A;  1FAO A;  2EJ8 A;  3RCP A;  4HAT B;  2DHK A;  2Z0O A;  1FGZ A;  2JP2 A;  3PP2 A;  3KRW A;  3P7Z A;  5D3X A;  3HK0 A;  2KR0 A;  3SYX A;  5HE2 A;  4XWX A;  4IFS A;  1WI1 A;  3PVU A;  3OHM B;  1NTY A;  1RRP B;  2EC1 A;  2CRF A;  1GG3 A;  2N0Y A;  1Z87 A;  1LW3 A;  3B77 A;  1DDV A;  2RGN B;  5IRS A;  2K2U A;  1SHC A;  1XD4 A;  3F5R A;  2YRY A;  1PFJ A;  4K81 A;  1WJM A;  2MKR A;  1MK9 B;  4NSW A;  4Z2N A;  2KUP A;  4GOU A;  2DYQ A;  3PSC A;  3QIJ A;  5C5B B;  4DXA B;  1X1F A;  2LUL A;  3MPX A;  1V61 A;  5JHG A;  3FM8 C;  3SNH A;  1LB1 A;  2P0D A;  2J59 M;  2DTC A;  3CXB B;  3UZT A;  4Z2M B;  5KQ4 A;  5LG4 B;  5JP4 A;  3QWM A;  1BTK A;  1U5F A;  1UNR A;  2KCJ A;  2Z0Q A;  4P7I A;  5D3V A;  2Z14 A;  2DHJ A;  2YT2 A;  2AL6 A;  2I5C A;  2J0J A;  4CHJ A;  5JHH A;  2GCJ A;  4YON A;  3NWF A;  2KIG A;  2DX1 A;  3HIE A;  4HAW B;  1MPH A;  4A6H A;  4CYE A;  4HDO A;  2M14 A;  1BTN A;  4A6K A;  2QKL A;  3GYP A;  4DIX A;  3HSA A;  3IVF A;  2D2Q A;  2UVM A;  5J3Y A;  4HAV B;  1WJ1 A;  2RNR B;  2BCJ A;  2W2W A;  3GYO A;  4QJ3 B;  3HQC A;  1UEF A;  4HAU B;  2DA0 A;  2P8V A;  2ZPY A;  4OSN A;  2I1K A;  5D27 A;  1P6S A;  4K17 A;  3SO6 A;  2L2I A;  3ODX A;  2OTX A;  1ZYI A;  3U7D A;  4C0A A;  1NTV A;  3A98 B;  2RLO A;  5JLJ B;  2D11 A;  3QBV B;  2J0K A;  5HE3 A;  3M1I B;  3SUZ A;  3V5W A;  3N7C A;  1DDW A;  4D0N B;  1X05 A;  2D9V A;  1QQG A;  3BJI A;  3AU4 A;  3FVC A;  5KQ1 A;  2YS3 A;  4PQ0 A;  2DHI A;  2UZR A;  1U2B A;  1BWN A;  2M38 A;  1NI2 A;  2MFQ A;  4H8S A;  1KZ7 A;  1P5T A;  3PVW A;  2LOZ A;  2ZKM X;  2DX5 A;  2DYN A;  4QJ4 B;  1MI1 A;  4HHV A;  3A58 A;  3ML4 A;  1MAI A;  3FSS A;  1U27 A;  4KHO A;  4HDQ A;  3OAN A;  3U8Z A;  2NMB A;  3D8E A;  2IYB A;  1V5P A;  3NWA A;  4F7U P;  5CLQ B;  5C5B A;  1NU2 A;  2FJU B;  4D6W A;  4A6F A;  5M4Y B;  1ZVR A;  1FGY A;  4HB0 B; 
#chains in the Genus database with same CATH homology
 4DBB A;  3KY9 A;  2P0H A;  1KI1 B;  1X86 A;  1X11 A;  3D8F A;  4EJN A;  5C79 A;  2ADZ A;  4PNK A;  4HB2 B;  3ODW A;  1UPR A;  2EMT A;  1KZG A;  4ZRI A;  3ULB A;  3F0W A;  2LG1 A;  2YT0 A;  3PEG A;  2YVC A;  3AU5 A;  2Y8G A;  1ISN A;  2R09 A;  1DYN A;  3LJU X;  5CLL B;  1MIZ B;  1AQC A;  1OQN A;  1W1H A;  2YT1 A;  2Y8F A;  3PG7 A;  2RUK B;  4K2P A;  3MDB C;  2R0D A;  3DXC A;  1GC7 A;  4KHB B;  2Q13 A;  2LOX A;  1QC6 A;  1ZM0 A;  4BBK A;  5C16 A;  1V88 A;  1EAZ A;  3A8P A;  2DN6 A;  2DLW A;  2RSG A;  5DHA B;  2CY4 A;  4ZRJ A;  1XX0 A;  3CIK A;  2K2J A;  4DX9 0;  4KHA A;  5J3Q A;  2LKO A;  2D4Q A;  1E5W A;  5DHF B;  3WA0 A;  4EKU A;  1ZC4 B;  4HAZ B;  5J3T A;  4KAX B;  3FEH A;  2I1J A;  2D9W A;  2HE7 A;  2OQB A;  2H7D A;  1BAK A;  1J0W A;  1WVH A;  2V76 A;  2QKM A;  2ELB A;  2FJL A;  2L1C A;  1P3R A;  2YF0 A;  3TVV A;  4IAP A;  1DRO A;  1H10 A;  4GZU A;  1DBH A;  2VSZ A;  3KRX A;  5LON B;  1H4R A;  3AJ4 A;  2H7E A;  5GOW B;  2EMS A;  1SGH A;  2COA A;  2VKI A;  1I7A A;  2D10 A;  4WVF B;  4GXB A;  2W2X C;  1U5D A;  1TQZ A;  1WG7 A;  3KZ1 A;  1PLS A;  1EF1 A;  1K5G B;  3ZDT A;  1EVH A;  4K2O A;  1XOD A;  2PZ1 A;  1Y5O A;  2LYD A;  1DDM A;  3TCA A;  4GN1 A;  1IRS A;  2E2X A;  3G9W A;  1U5G A;  2COF A;  4F7H A;  2YS1 A;  5D3W A;  2J0M A;  4TYZ A;  3TW1 A;  3VIA A;  2I5F A;  3T06 A;  4Y94 A;  5DH9 B;  1OY2 A;  2Y7B A;  4CHM A;  1MK7 B;  1N3H A;  2RVB B;  2X18 A;  1OMW A;  3NSU A;  2D9Z A;  3PZD A;  5LOP B;  2XQN M;  2ROV A;  2DFK A;  1MKE A;  3TFM A;  2Z0P A;  2GS0 A;  2D9Y A;  2VRW B;  1TXD A;  1GC6 A;  4A5K A;  5HE1 A;  4IOY X;  2DKQ A;  2HTH B;  5DIF B;  2YS5 A;  4GMX B;  2G35 A;  1J19 A;  1Q67 A;  2D9X A;  1FOE A;  5L81 A;  4MK0 A;  3DXD A;  3KSY A;  5FI1 A;  5FI0 A;  2ELA A;  3TO1 A;  1XR0 B;  1I2H A;  4HB4 B;  4KVG B;  2AEH A;  1RJ2 A;  2ROZ B;  4L6E A;  4A6F B;  1FHX A;  1X1G A;  5D3Y A;  1V5U A;  4DX8 A;  4GMV A;  1Y19 B;  3PVL A;  1K5D B;  4WSF A;  3BIN A;  1TJ6 A;  2MDX A;  2P0F A;  1M7R A;  3D8D A;  1B55 A;  1W1G A;  2GJY A;  3SV1 A;  4NY0 A;  1EGX A;  2CY5 A;  1V89 A;  1PMS A;  1FB8 A;  2COD A;  4HAY B;  3ZVR A;  4F7G A;  5C6R A;  1ZSQ A;  2COC A;  4MY6 A;  2DKP A;  1U29 A;  3ODO A;  2IFS A;  1XCG A;  4HB3 B;  2W2X D;  4MT7 A;  5KCV A;  4GPT B;  2GCL A;  4WJ7 A;  3X23 A;  1ZC3 B;  5DI9 B;  3O96 A;  2YSZ A;  1FHO A;  3A8Q A;  3P6A A;  4TKN A;  1WGU A;  2MWN B;  1UNQ A;  1M7E A;  2NZ8 B;  1V5M A;  1AWE A;  1W1D A;  3ULC A;  4EMO A;  2UZS A;  1FHW A;  5HE0 A;  1U5E A;  5EFX A;  2CAY A;  3WYF B;  3HW2 B;  4YL8 A;  1UPQ A;  1UNP A;  1WGQ A;  2N23 A;  2KGX B;  4HAX B;  1XKE A;  3DXE A;  4ZRK A;  3VOQ A;  2K00 A;  1MIX A;  4B6H A;  1FAO A;  2EJ8 A;  3RCP A;  4HAT B;  2DHK A;  2Z0O A;  1FGZ A;  2JP2 A;  3PP2 A;  3KRW A;  3P7Z A;  5D3X A;  3HK0 A;  3SYX A;  5HE2 A;  4XWX A;  4IFS A;  1WI1 A;  3PVU A;  1NTY A;  1RRP B;  2EC1 A;  2CRF A;  1GG3 A;  2N0Y A;  1Z87 A;  1LW3 A;  1DDV A;  2RGN B;  2K2U A;  1SHC A;  1XD4 A;  3F5R A;  2YRY A;  1PFJ A;  4K81 A;  1WJM A;  2MKR A;  1MK9 B;  4NSW A;  4Z2N A;  2KUP A;  2DYQ A;  3PSC A;  3QIJ A;  5C5B B;  4DXA B;  1X1F A;  2LUL A;  3MPX A;  1V61 A;  5JHG A;  3FM8 C;  3SNH A;  1LB1 A;  2P0D A;  2J59 M;  2DTC A;  3CXB B;  3UZT A;  4Z2M B;  5KQ4 A;  5JP4 A;  3QWM A;  1BTK A;  1U5F A;  1UNR A;  2KCJ A;  2Z0Q A;  4P7I A;  5D3V A;  2DHJ A;  4CHJ A;  2AL6 A;  2I5C A;  2J0J A;  5JHH A;  2GCJ A;  4YON A;  2DX1 A;  4HAW B;  1MPH A;  4A6H A;  4CYE A;  4HDO A;  2M14 A;  1BTN A;  4A6K A;  2QKL A;  3GYP A;  3IVF A;  2D2Q A;  2UVM A;  5J3Y A;  4HAV B;  1WJ1 A;  2RNR B;  2BCJ A;  2W2W A;  3GYO A;  3HQC A;  1UEF A;  4HAU B;  2DA0 A;  2P8V A;  2ZPY A;  2I1K A;  5D27 A;  1P6S A;  4K17 A;  3SO6 A;  2L2I A;  3ODX A;  2OTX A;  3U7D A;  4C0A A;  1NTV A;  3A98 B;  2RLO A;  5JLJ B;  2D11 A;  3QBV B;  2J0K A;  5HE3 A;  3M1I B;  3SUZ A;  3V5W A;  3N7C A;  1DDW A;  4D0N B;  1X05 A;  2D9V A;  1QQG A;  3BJI A;  3AU4 A;  5KQ1 A;  2YS3 A;  4PQ0 A;  2DHI A;  2UZR A;  1U2B A;  1BWN A;  2M38 A;  1NI2 A;  2MFQ A;  4H8S A;  1KZ7 A;  1P5T A;  3PVW A;  2LOZ A;  2DX5 A;  2DYN A;  4HHV A;  3ML4 A;  1MAI A;  3FSS A;  1U27 A;  4KHO A;  4HDQ A;  3OAN A;  3U8Z A;  2NMB A;  3D8E A;  2IYB A;  1V5P A;  4F7U P;  5CLQ B;  5C5B A;  1NU2 A;  4A6F A;  1ZVR A;  1FGY A;  4HB0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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