5D3YA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
151
structure length
136
Chain Sequence
ALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus 40
structure length 136
sequence length 151
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3yA00
4P7IA 1U5FA 2L2IA 3X23A 1WGQA 2YRYA 3FSSA 2CRFA 2DHKA 1TXDA 1RJ2A 2LG1A 3WA0A 1WVHA 2IFSA 5L81A 2VRWB 3DXCA 1EAZA 1UNPA 2RUKB 1FAOA 4YONA 1U5EA 2NZ8B 3MDBC 3D8DA 1V88A 1IRSA 5C5BA 4GPTB 1M7EA 3CIKA 5KCVA 1LB1A 3QIJA 4ZRIA 1V89A 5KQ4A 3SUZA 2YF0A 2COAA 1WI1A 2HTHB 2YS3A 2Z0PA 3G9WA 2RVBB 4KHAA 1ISNA 1DDWA 4IAPA 4KHOA 1NTVA 5D3YA 4HDOA 1XODA 2K2JA 2COFA 3SV1A 1X1FA 1E5WA 3SO6A 1XCGA 2LYDA 3KZ1A 3ML4A 5HE0A 3TVVA 2YT0A 3PSCA 1MIZB 1J0WA 2KCJA 3SNHA 2P0DA 1XKEA 3ZDTA 2J59M 1P3RA 2DX5A 3N7CA 2I1JA 4NSWA 5EFXA 3FM8C 1FGYA 2ELBA 2Q13A 5DI9B 1SHCA 1ZM0A 1ZC4B 1EVHA 4GZUA 3P6AA 4HB4B 2E2XA 1UNQA 2HE7A 2J0JA 1DDMA 1B55A 1ZVRA 2Y8FA 3O96A 4GMVA 4IOYX 2DLWA 1GG3A 2K00A 2P0HA 5GOWB 1H4RA 4H8SA 4K81A 4DX90 2CAYA 2BCJA 3D8FA 3IVFA 3PVWA 5LONB 3M1IB 2M38A 1WJ1A 2D9XA 4HAZB 2YVCA 3HQCA 4HAXB 1MK9B 4NY0A 5J3TA 2RNRB 3U8ZA 3SYXA 4HB2B 4TYZA 4MY6A 4F7HA 1X1GA 1DYNA 3QWMA 2H7EA 2OQBA 4A6KA 3GYOA 2DKQA 1MPHA 1V5PA 2K2UA 2D9YA 1W1DA 2L1CA 2MFQA 3U7DA 2ZPYA 1NI2A 3KY9A 1DDVA 4L6EA 4C0AA 2I5CA 3KSYA 4Z2MB 1EF1A 3FEHA 1I2HA 2GS0A 2AEHA 2DKPA 3TW1A 3VIAA 1BAKA 1QQGA 5JLJB 2D11A 2QKMA 1ZSQA 2VSZA 1FOEA 4A5KA 3BJIA 2YS5A 1U5GA 1WJMA 2LOXA 5JHGA 1MKEA 1SGHA 2V76A 4CYEA 1TJ6A 1KI1B 2CODA 3PVLA 4KVGB 2XQNM 2LKOA 5CLQB 1V5MA 4ZRJA 5D3VA 4EKUA 2KUPA 2NMBA 5HE3A 4GMXB 2MDXA 1I7AA 2EC1A 2DA0A 3PG7A 1Y19B 1FB8A 2LULA 2D9ZA 1U2BA 2DX1A 1GC6A 4GN1A 5HE1A 1UNRA 2X18A 1M7RA 1J19A 4HAVB 4D0NB 2JP2A 4CHMA 2D9WA 2UZRA 1BTNA 2GCLA 2RSGA 2VKIA 3VOQA 2DYNA 1GC7A 4CHJA 2DTCA 5FI0A 2W2XC 4GXBA 4DXAB 4Z2NA 3DXEA 1V5UA 3ODOA 4KAXB 3BINA 1UEFA 2H7DA 4XWXA 4F7GA 4HDQA 2Y7BA 3A8PA 3F5RA 4PQ0A 4HAYB 2N23A 5DHFB 5C16A 3UZTA 2GCJA 3PEGA 3AJ4A 4Y94A 4BBKA 3OANA 5J3QA 3V5WA 1P6SA 2YT1A 2EMSA 1BTKA 4HATB 2UVMA 1U5DA 1H10A 3MPXA 3CXBB 1FGZA 2W2WA 3PZDA 1W1HA 3AU4A 3ODWA 1WGUA 5HE2A 2ADZA 3P7ZA 2D2QA 2P0FA 4ZRKA 1X05A 2R09A 3F0WA 1XD4A 4HB0B 1Z87A 4PNKA 1Y5OA 2EJ8A 1FHXA 1AQCA 1LW3A 1DBHA 1X11A 1NTYA 2DHIA 4A6HA 2N0YA 4YL8A 4A6FB 4B6HA 1MK7B 1ZC3B 3A98B 4HB3B 4TKNA 1X86A 2IYBA 1K5DB 2R0DA 3T06A 1DROA 1OMWA 5FI1A 3D8EA 1K5GB 1W1GA 1QC6A 5KQ1A 1EGXA 2YSZA 2CY5A 3WYFB 1Q67A 1MAIA 3HK0A 3PP2A 3ZVRA 2M14A 2I1KA 5C79A 3QBVB 3KRWA 3TO1A 3ULBA 2GJYA 2RLOA 5C5BB 1UPRA 2UZSA 2FJLA 1OQNA 2DYQA 1U29A 1FHOA 2COCA 3TFMA 1WG7A 2KGXB 1AWEA 4WVFB 2D4QA 2ELAA 5JHHA 5C6RA 2OTXA 2J0MA 3KRXA 4DX8A 2YS1A 5DH9B 4KHBB 1V61A 2P8VA 2D10A 1N3HA 3TCAA 2J0KA 2Z0OA 3RCPA 1KZGA 4F7UP 3NSUA 4MK0A 4WSFA 2DHJA 3AU5A 5DIFB 4HHVA 2I5FA 1NU2A 4K2PA 2G35A 2QKLA 5D27A 2Z0QA 1XX0A 1UPQA 2EMTA 3DXDA 5D3XA 4IFSA 1PFJA 5CLLB 2LOZA 1PLSA 2RGNB 3LJUX 3ULCA 1P5TA 2DN6A 1KZ7A 2MWNB 1FHWA 2DFKA 1MIXA 3A8QA 4EMOA 2Y8GA 2AL6A 5DHAB 1PMSA 4K2OA 2CY4A 4HAWB 4DBBA 3ODXA 2D9VA 1BWNA 1XR0B 4HAUB 4WJ7A 5J3YA 2MKRA 3GYPA 4A6FA 2W2XD 1TQZA 4EJNA 5LOPB 3PVUA 4MT7A 1RRPB 2ROZB 2ROVA 1OY2A 4K17A 1U27A 5D3WA 5JP4A 3HW2B 2PZ1A
chains in the Genus database with same CATH superfamily
4P7IA 1U5FA 2L2IA 3X23A 1WGQA 2YRYA 3FSSA 2CRFA 2DHKA 1TXDA 1RJ2A 2LG1A 4QJ4B 2R2YA 3WA0A 1WVHA 2IFSA 5L81A 2VRWB 3DXCA 1EAZA 1UNPA 2RUKB 1FAOA 4YONA 1U5EA 2NZ8B 2Z13A 3D8DA 3MDBC 1V88A 1IRSA 5C5BA 4GPTB 1M7EA 3CIKA 5KCVA 1LB1A 3QIJA 4ZRIA 1V89A 5KQ4A 3SUZA 2YF0A 2COAA 2Z14A 3HSAA 1WI1A 2HTHB 2YS3A 2Z0PA 3G9WA 2RVBB 4KHAA 1ISNA 1DDWA 4IAPA 4KHOA 1NTVA 5D3YA 4HDOA 1XODA 2K2JA 2COFA 3SV1A 4KHBA 1X1FA 1E5WA 3SO6A 1XCGA 4L1RA 2K49A 2LYDA 3KZ1A 3ML4A 5HE0A 3TVVA 2YT0A 3PSCA 3NWDA 1MIZB 1J0WA 2GUMA 2KCJA 3SNHA 2P0DA 1XKEA 3ZDTA 2J59M 1P3RA 2DX5A 3N7CA 2I1JA 4NSWA 5EFXA 3HIEA 3FM8C 1FGYA 2ELBA 2Q13A 5DI9B 1SHCA 1ZM0A 1ZC4B 1EVHA 4GZUA 4CSQA 3P6AA 4HB4B 2E2XA 1UNQA 2HE7A 2J0JA 1DDMA 1B55A 1ZVRA 2Y8FA 3O96A 4GMVA 4IOYX 2DLWA 1GG3A 2K00A 2P0HA 5GOWB 1H4RA 4H8SA 4K81A 4DX90 2CAYA 2BCJA 3D8FA 3IVFA 3PVWA 5LONB 3M1IB 2M38A 1WJ1A 2D9XA 4HAZB 2YVCA 3HQCA 4HAXB 1MK9B 4NY0A 5J3TA 2RNRB 3U8ZA 3SYXA 4HB2B 4TYZA 4MY6A 2KR0A 4F7HA 1X1GA 1DYNA 3QWMA 2H7EA 2OQBA 4A6KA 3GYOA 2DKQA 1MPHA 1V5PA 2K2UA 1MI1A 1W1DA 2D9YA 2L1CA 2MFQA 3U7DA 2ZPYA 1NI2A 3KY9A 1DDVA 4L6EA 4C0AA 2I5CA 3KSYA 4Z2MB 1EF1A 3FEHA 1I2HA 2GS0A 2AEHA 2DKPA 2FJUB 5LG4B 3TW1A 4QJ5B 3VIAA 1BAKA 1QQGA 5JLJB 2D11A 2QKMA 1ZSQA 2VSZA 1FOEA 4A5KA 3BJIA 2YS5A 1U5GA 1WJMA 2LOXA 5JHGA 1MKEA 1SGHA 2K8EA 2V76A 4CYEA 1TJ6A 1KI1B 2CODA 3PVLA 4KVGB 2XQNM 2LKOA 5CLQB 1V5MA 4ZRJA 5D3VA 4EKUA 2KUPA 2NMBA 3A58A 4D6WA 4GNKB 5HE3A 4GMXB 5M4YB 2MDXA 1I7AA 2EC1A 2DA0A 3PG7A 1Y19B 1FB8A 2LULA 2D9ZA 1U2BA 2DX1A 4OSNA 1GC6A 4GN1A 5HE1A 1UNRA 2X18A 1M7RA 1J19A 4HAVB 4D0NB 4QXAB 2JP2A 4CHMA 2D9WA 2UZRA 1BTNA 2GCLA 2RSGA 2VKIA 3VOQA 2DYNA 1GC7A 4CHJA 2DTCA 5FI0A 2W2XC 4GXBA 4DXAB 4Z2NA 3DCXA 3DXEA 1V5UA 3ODOA 4KAXB 3BINA 1UEFA 2H7DA 4XWXA 4F7GA 4HDQA 2Y7BA 3A8PA 3F5RA 4PQ0A 4HAYB 2N23A 5DHFB 5C16A 2YT2A 3UZTA 2GCJA 3PEGA 3AJ4A 4Y94A 4BBKA 3OANA 5J3QA 3V5WA 1P6SA 2YT1A 2EMSA 1BTKA 4HATB 2UVMA 1U5DA 1H10A 3MPXA 3CXBB 1FGZA 1ZYIA 2W2WA 3NWFA 1W1HA 3AU4A 3PZDA 3ODWA 2KIGA 4GOUA 1WGUA 5HE2A 2ADZA 3P7ZA 2D2QA 2P0FA 4ZRKA 1X05A 2R09A 3F0WA 1XD4A 4HB0B 1Z87A 4PNKA 1Y5OA 2KIEA 2EJ8A 1FHXA 1AQCA 1LW3A 1DBHA 1X11A 1NTYA 2DHIA 4A6HA 2N0YA 4YL8A 4A6FB 3B77A 4B6HA 1MK7B 1ZC3B 3A98B 4HB3B 4TKNA 1X86A 2IYBA 1K5DB 2R0DA 3T06A 1DROA 1OMWA 3NW8A 5FI1A 3D8EA 2RRFA 1K5GB 1W1GA 1QC6A 5IRSA 5KQ1A 1EGXA 2YSZA 2CY5A 3WYFB 1Q67A 1MAIA 4HSIA 3HK0A 5I2MA 2NBVA 3PP2A 3ZVRA 2M14A 2I1KA 5C79A 3QBVB 3KRWA 5I2SA 3TO1A 3ULBA 2GJYA 2RLOA 5C5BB 1UPRA 2UZSA 2FJLA 1OQNA 2DYQA 1U29A 1FHOA 2COCA 3TFMA 1T77A 1WG7A 2KGXB 1AWEA 4WVFB 2D4QA 2ELAA 3FVCA 5JHHA 5C6RA 2OTXA 2J0MA 3KRXA 2KUQA 4DX8A 2YS1A 3NWAA 3U12A 5DH9B 4KHBB 2Z4DA 1V61A 2P8VA 2D10A 1N3HA 3TCAA 2Z59A 2J0KA 2Z0OA 3RCPA 1KZGA 4F7UP 3NSUA 4MK0A 4WSFA 2DHJA 3AU5A 5DIFB 4HHVA 2I5FA 1NU2A 4K2PA 2G35A 2QKLA 5D27A 2Z0QA 1XX0A 1UPQA 2EMTA 3DXDA 5D3XA 4IFSA 1PFJA 5CLLB 2LOZA 1PLSA 2RGNB 3LJUX 3ULCA 1P5TA 2DN6A 1KZ7A 2MWNB 1FHWA 2DFKA 1MIXA 3A8QA 4EMOA 2Y8GA 2AL6A 4OT1A 5DHAB 4DIXA 1PMSA 4K2OA 2CY4A 4HAWB 4DBBA 3ODXA 2D9VA 4QJ3B 1BWNA 1XR0B 4HAUB 4WJ7A 5J3YA 2MKRA 2ZKMX 3GYPA 4A6FA 3OHMB 2W2XD 1TQZA 4EJNA 5LOPB 3PVUA 4MT7A 1RRPB 2ROZB 2ROVA 1OY2A 4K17A 1U27A 5D3WA 5JP4A 3HW2B 2PZ1A
chains in the Genus database with same CATH topology
4P7IA 1U5FA 2L2IA 3X23A 1WGQA 2YRYA 3FSSA 2CRFA 2DHKA 1TXDA 1RJ2A 2LG1A 3WA0A 1WVHA 2IFSA 5L81A 2VRWB 3DXCA 1EAZA 1UNPA 2RUKB 1FAOA 4YONA 1U5EA 2NZ8B 3MDBC 3D8DA 1V88A 1IRSA 5C5BA 4GPTB 1M7EA 3CIKA 5KCVA 1LB1A 3QIJA 4ZRIA 1V89A 5KQ4A 3SUZA 2YF0A 2COAA 1WI1A 2HTHB 2YS3A 2Z0PA 3G9WA 2RVBB 4KHAA 1ISNA 1DDWA 4IAPA 4KHOA 1NTVA 5D3YA 4HDOA 1XODA 2K2JA 2COFA 3SV1A 1X1FA 1E5WA 3SO6A 1XCGA 2LYDA 3KZ1A 3ML4A 5HE0A 3TVVA 2YT0A 3PSCA 1MIZB 1J0WA 2KCJA 3SNHA 2P0DA 1XKEA 3ZDTA 2J59M 1P3RA 2DX5A 3N7CA 2I1JA 4NSWA 5EFXA 3FM8C 1FGYA 2ELBA 2Q13A 5DI9B 1SHCA 1ZM0A 1ZC4B 1EVHA 4GZUA 3P6AA 4HB4B 2E2XA 1UNQA 2HE7A 2J0JA 1DDMA 1B55A 1ZVRA 2Y8FA 3O96A 4GMVA 4IOYX 2DLWA 1GG3A 2K00A 2P0HA 5GOWB 1H4RA 4H8SA 4K81A 4DX90 2CAYA 2BCJA 3D8FA 3IVFA 3PVWA 5LONB 3M1IB 2M38A 1WJ1A 2D9XA 4HAZB 2YVCA 3HQCA 4HAXB 1MK9B 4NY0A 5J3TA 2RNRB 3U8ZA 3SYXA 4HB2B 4TYZA 4MY6A 4F7HA 1X1GA 1DYNA 3QWMA 2H7EA 2OQBA 4A6KA 3GYOA 2DKQA 1MPHA 1V5PA 2K2UA 2D9YA 1W1DA 2L1CA 2MFQA 3U7DA 2ZPYA 1NI2A 3KY9A 1DDVA 4L6EA 4C0AA 2I5CA 3KSYA 4Z2MB 1EF1A 3FEHA 1I2HA 2GS0A 2AEHA 2DKPA 3TW1A 3VIAA 1BAKA 1QQGA 5JLJB 2D11A 2QKMA 1ZSQA 2VSZA 1FOEA 4A5KA 3BJIA 2YS5A 1U5GA 1WJMA 2LOXA 5JHGA 1MKEA 1SGHA 2V76A 4CYEA 1TJ6A 1KI1B 2CODA 3PVLA 4KVGB 2XQNM 2LKOA 5CLQB 1V5MA 4ZRJA 5D3VA 4EKUA 2KUPA 2NMBA 5HE3A 4GMXB 2MDXA 1I7AA 2EC1A 2DA0A 3PG7A 1Y19B 1FB8A 2LULA 2D9ZA 1U2BA 2DX1A 1GC6A 4GN1A 5HE1A 1UNRA 2X18A 1M7RA 1J19A 4HAVB 4D0NB 2JP2A 4CHMA 2D9WA 2UZRA 1BTNA 2GCLA 2RSGA 2VKIA 3VOQA 2DYNA 1GC7A 4CHJA 2DTCA 5FI0A 2W2XC 4GXBA 4DXAB 4Z2NA 3DXEA 1V5UA 3ODOA 4KAXB 3BINA 1UEFA 2H7DA 4XWXA 4F7GA 4HDQA 2Y7BA 3A8PA 3F5RA 4PQ0A 4HAYB 2N23A 5DHFB 5C16A 3UZTA 2GCJA 3PEGA 3AJ4A 4Y94A 4BBKA 3OANA 5J3QA 3V5WA 1P6SA 2YT1A 2EMSA 1BTKA 4HATB 2UVMA 1U5DA 1H10A 3MPXA 3CXBB 1FGZA 2W2WA 3PZDA 1W1HA 3AU4A 3ODWA 1WGUA 5HE2A 2ADZA 3P7ZA 2D2QA 2P0FA 4ZRKA 1X05A 2R09A 3F0WA 1XD4A 4HB0B 1Z87A 4PNKA 1Y5OA 2EJ8A 1FHXA 1AQCA 1LW3A 1DBHA 1X11A 1NTYA 2DHIA 4A6HA 2N0YA 4YL8A 4A6FB 4B6HA 1MK7B 1ZC3B 3A98B 4HB3B 4TKNA 1X86A 2IYBA 1K5DB 2R0DA 3T06A 1DROA 1OMWA 5FI1A 3D8EA 1K5GB 1W1GA 1QC6A 5KQ1A 1EGXA 2YSZA 2CY5A 3WYFB 1Q67A 1MAIA 3HK0A 3PP2A 3ZVRA 2M14A 2I1KA 5C79A 3QBVB 3KRWA 3TO1A 3ULBA 2GJYA 2RLOA 5C5BB 1UPRA 2UZSA 2FJLA 1OQNA 2DYQA 1U29A 1FHOA 2COCA 3TFMA 1WG7A 2KGXB 1AWEA 4WVFB 2D4QA 2ELAA 5JHHA 5C6RA 2OTXA 2J0MA 3KRXA 4DX8A 2YS1A 5DH9B 4KHBB 1V61A 2P8VA 2D10A 1N3HA 3TCAA 2J0KA 2Z0OA 3RCPA 1KZGA 4F7UP 3NSUA 4MK0A 4WSFA 2DHJA 3AU5A 5DIFB 4HHVA 2I5FA 1NU2A 4K2PA 2G35A 2QKLA 5D27A 2Z0QA 1XX0A 1UPQA 2EMTA 3DXDA 5D3XA 4IFSA 1PFJA 5CLLB 2LOZA 1PLSA 2RGNB 3LJUX 3ULCA 1P5TA 2DN6A 1KZ7A 2MWNB 1FHWA 2DFKA 1MIXA 3A8QA 4EMOA 2Y8GA 2AL6A 5DHAB 1PMSA 4K2OA 2CY4A 4HAWB 4DBBA 3ODXA 2D9VA 1BWNA 1XR0B 4HAUB 4WJ7A 5J3YA 2MKRA 3GYPA 4A6FA 2W2XD 1TQZA 4EJNA 5LOPB 3PVUA 4MT7A 1RRPB 2ROZB 2ROVA 1OY2A 4K17A 1U27A 5D3WA 5JP4A 3HW2B 2PZ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P7I A;  1U5F A;  2L2I A;  3X23 A;  1WGQ A;  2YRY A;  3FSS A;  2CRF A;  2DHK A;  1TXD A;  1RJ2 A;  2LG1 A;  3WA0 A;  1WVH A;  2IFS A;  5L81 A;  2VRW B;  3DXC A;  1EAZ A;  1UNP A;  2RUK B;  1FAO A;  4YON A;  1U5E A;  2NZ8 B;  3MDB C;  3D8D A;  1V88 A;  1IRS A;  5C5B A;  4GPT B;  1M7E A;  3CIK A;  5KCV A;  1LB1 A;  3QIJ A;  4ZRI A;  1V89 A;  5KQ4 A;  3SUZ A;  2YF0 A;  2COA A;  1WI1 A;  2HTH B;  2YS3 A;  2Z0P A;  3G9W A;  2RVB B;  4KHA A;  1ISN A;  1DDW A;  4IAP A;  4KHO A;  1NTV A;  5D3Y A;  4HDO A;  1XOD A;  2K2J A;  2COF A;  3SV1 A;  1X1F A;  1E5W A;  3SO6 A;  1XCG A;  2LYD A;  3KZ1 A;  3ML4 A;  5HE0 A;  3TVV A;  2YT0 A;  3PSC A;  1MIZ B;  1J0W A;  2KCJ A;  3SNH A;  2P0D A;  1XKE A;  3ZDT A;  2J59 M;  1P3R A;  2DX5 A;  3N7C A;  2I1J A;  4NSW A;  5EFX A;  3FM8 C;  1FGY A;  2ELB A;  2Q13 A;  5DI9 B;  1SHC A;  1ZM0 A;  1ZC4 B;  1EVH A;  4GZU A;  3P6A A;  4HB4 B;  2E2X A;  1UNQ A;  2HE7 A;  2J0J A;  1DDM A;  1B55 A;  1ZVR A;  2Y8F A;  3O96 A;  4GMV A;  4IOY X;  2DLW A;  1GG3 A;  2K00 A;  2P0H A;  5GOW B;  1H4R A;  4H8S A;  4K81 A;  4DX9 0;  2CAY A;  2BCJ A;  3D8F A;  3IVF A;  3PVW A;  5LON B;  3M1I B;  2M38 A;  1WJ1 A;  2D9X A;  4HAZ B;  2YVC A;  3HQC A;  4HAX B;  1MK9 B;  4NY0 A;  5J3T A;  2RNR B;  3U8Z A;  3SYX A;  4HB2 B;  4TYZ A;  4MY6 A;  4F7H A;  1X1G A;  1DYN A;  3QWM A;  2H7E A;  2OQB A;  4A6K A;  3GYO A;  2DKQ A;  1MPH A;  1V5P A;  2K2U A;  2D9Y A;  1W1D A;  2L1C A;  2MFQ A;  3U7D A;  2ZPY A;  1NI2 A;  3KY9 A;  1DDV A;  4L6E A;  4C0A A;  2I5C A;  3KSY A;  4Z2M B;  1EF1 A;  3FEH A;  1I2H A;  2GS0 A;  2AEH A;  2DKP A;  3TW1 A;  3VIA A;  1BAK A;  1QQG A;  5JLJ B;  2D11 A;  2QKM A;  1ZSQ A;  2VSZ A;  1FOE A;  4A5K A;  3BJI A;  2YS5 A;  1U5G A;  1WJM A;  2LOX A;  5JHG A;  1MKE A;  1SGH A;  2V76 A;  4CYE A;  1TJ6 A;  1KI1 B;  2COD A;  3PVL A;  4KVG B;  2XQN M;  2LKO A;  5CLQ B;  1V5M A;  4ZRJ A;  5D3V A;  4EKU A;  2KUP A;  2NMB A;  5HE3 A;  4GMX B;  2MDX A;  1I7A A;  2EC1 A;  2DA0 A;  3PG7 A;  1Y19 B;  1FB8 A;  2LUL A;  2D9Z A;  1U2B A;  2DX1 A;  1GC6 A;  4GN1 A;  5HE1 A;  1UNR A;  2X18 A;  1M7R A;  1J19 A;  4HAV B;  4D0N B;  2JP2 A;  4CHM A;  2D9W A;  2UZR A;  1BTN A;  2GCL A;  2RSG A;  2VKI A;  3VOQ A;  2DYN A;  1GC7 A;  4CHJ A;  2DTC A;  5FI0 A;  2W2X C;  4GXB A;  4DXA B;  4Z2N A;  3DXE A;  1V5U A;  3ODO A;  4KAX B;  3BIN A;  1UEF A;  2H7D A;  4XWX A;  4F7G A;  4HDQ A;  2Y7B A;  3A8P A;  3F5R A;  4PQ0 A;  4HAY B;  2N23 A;  5DHF B;  5C16 A;  3UZT A;  2GCJ A;  3PEG A;  3AJ4 A;  4Y94 A;  4BBK A;  3OAN A;  5J3Q A;  3V5W A;  1P6S A;  2YT1 A;  2EMS A;  1BTK A;  4HAT B;  2UVM A;  1U5D A;  1H10 A;  3MPX A;  3CXB B;  1FGZ A;  2W2W A;  3PZD A;  1W1H A;  3AU4 A;  3ODW A;  1WGU A;  5HE2 A;  2ADZ A;  3P7Z A;  2D2Q A;  2P0F A;  4ZRK A;  1X05 A;  2R09 A;  3F0W A;  1XD4 A;  4HB0 B;  1Z87 A;  4PNK A;  1Y5O A;  2EJ8 A;  1FHX A;  1AQC A;  1LW3 A;  1DBH A;  1X11 A;  1NTY A;  2DHI A;  4A6H A;  2N0Y A;  4YL8 A;  4A6F B;  4B6H A;  1MK7 B;  1ZC3 B;  3A98 B;  4HB3 B;  4TKN A;  1X86 A;  2IYB A;  1K5D B;  2R0D A;  3T06 A;  1DRO A;  1OMW A;  5FI1 A;  3D8E A;  1K5G B;  1W1G A;  1QC6 A;  5KQ1 A;  1EGX A;  2YSZ A;  2CY5 A;  3WYF B;  1Q67 A;  1MAI A;  3HK0 A;  3PP2 A;  3ZVR A;  2M14 A;  2I1K A;  5C79 A;  3QBV B;  3KRW A;  3TO1 A;  3ULB A;  2GJY A;  2RLO A;  5C5B B;  1UPR A;  2UZS A;  2FJL A;  1OQN A;  2DYQ A;  1U29 A;  1FHO A;  2COC A;  3TFM A;  1WG7 A;  2KGX B;  1AWE A;  4WVF B;  2D4Q A;  2ELA A;  5JHH A;  5C6R A;  2OTX A;  2J0M A;  3KRX A;  4DX8 A;  2YS1 A;  5DH9 B;  4KHB B;  1V61 A;  2P8V A;  2D10 A;  1N3H A;  3TCA A;  2J0K A;  2Z0O A;  3RCP A;  1KZG A;  4F7U P;  3NSU A;  4MK0 A;  4WSF A;  2DHJ A;  3AU5 A;  5DIF B;  4HHV A;  2I5F A;  1NU2 A;  4K2P A;  2G35 A;  2QKL A;  5D27 A;  2Z0Q A;  1XX0 A;  1UPQ A;  2EMT A;  3DXD A;  5D3X A;  4IFS A;  1PFJ A;  5CLL B;  2LOZ A;  1PLS A;  2RGN B;  3LJU X;  3ULC A;  1P5T A;  2DN6 A;  1KZ7 A;  2MWN B;  1FHW A;  2DFK A;  1MIX A;  3A8Q A;  4EMO A;  2Y8G A;  2AL6 A;  5DHA B;  1PMS A;  4K2O A;  2CY4 A;  4HAW B;  4DBB A;  3ODX A;  2D9V A;  1BWN A;  1XR0 B;  4HAU B;  4WJ7 A;  5J3Y A;  2MKR A;  3GYP A;  4A6F A;  2W2X D;  1TQZ A;  4EJN A;  5LOP B;  3PVU A;  4MT7 A;  1RRP B;  2ROZ B;  2ROV A;  1OY2 A;  4K17 A;  1U27 A;  5D3W A;  5JP4 A;  3HW2 B;  2PZ1 A; 
#chains in the Genus database with same CATH topology
 4P7I A;  1U5F A;  2L2I A;  3X23 A;  1WGQ A;  2YRY A;  3FSS A;  2CRF A;  2DHK A;  1TXD A;  1RJ2 A;  2LG1 A;  4QJ4 B;  2R2Y A;  3WA0 A;  1WVH A;  2IFS A;  5L81 A;  2VRW B;  3DXC A;  1EAZ A;  1UNP A;  2RUK B;  1FAO A;  4YON A;  1U5E A;  2NZ8 B;  2Z13 A;  3D8D A;  3MDB C;  1V88 A;  1IRS A;  5C5B A;  4GPT B;  1M7E A;  3CIK A;  5KCV A;  1LB1 A;  3QIJ A;  4ZRI A;  1V89 A;  5KQ4 A;  3SUZ A;  2YF0 A;  2COA A;  2Z14 A;  3HSA A;  1WI1 A;  2HTH B;  2YS3 A;  2Z0P A;  3G9W A;  2RVB B;  4KHA A;  1ISN A;  1DDW A;  4IAP A;  4KHO A;  1NTV A;  5D3Y A;  4HDO A;  1XOD A;  2K2J A;  2COF A;  3SV1 A;  4KHB A;  1X1F A;  1E5W A;  3SO6 A;  1XCG A;  4L1R A;  2K49 A;  2LYD A;  3KZ1 A;  3ML4 A;  5HE0 A;  3TVV A;  2YT0 A;  3PSC A;  3NWD A;  1MIZ B;  1J0W A;  2GUM A;  2KCJ A;  3SNH A;  2P0D A;  1XKE A;  3ZDT A;  2J59 M;  1P3R A;  2DX5 A;  3N7C A;  2I1J A;  4NSW A;  5EFX A;  3HIE A;  3FM8 C;  1FGY A;  2ELB A;  2Q13 A;  5DI9 B;  1SHC A;  1ZM0 A;  1ZC4 B;  1EVH A;  4GZU A;  4CSQ A;  3P6A A;  4HB4 B;  2E2X A;  1UNQ A;  2HE7 A;  2J0J A;  1DDM A;  1B55 A;  1ZVR A;  2Y8F A;  3O96 A;  4GMV A;  4IOY X;  2DLW A;  1GG3 A;  2K00 A;  2P0H A;  5GOW B;  1H4R A;  4H8S A;  4K81 A;  4DX9 0;  2CAY A;  2BCJ A;  3D8F A;  3IVF A;  3PVW A;  5LON B;  3M1I B;  2M38 A;  1WJ1 A;  2D9X A;  4HAZ B;  2YVC A;  3HQC A;  4HAX B;  1MK9 B;  4NY0 A;  5J3T A;  2RNR B;  3U8Z A;  3SYX A;  4HB2 B;  4TYZ A;  4MY6 A;  2KR0 A;  4F7H A;  1X1G A;  1DYN A;  3QWM A;  2H7E A;  2OQB A;  4A6K A;  3GYO A;  2DKQ A;  1MPH A;  1V5P A;  2K2U A;  1MI1 A;  1W1D A;  2D9Y A;  2L1C A;  2MFQ A;  3U7D A;  2ZPY A;  1NI2 A;  3KY9 A;  1DDV A;  4L6E A;  4C0A A;  2I5C A;  3KSY A;  4Z2M B;  1EF1 A;  3FEH A;  1I2H A;  2GS0 A;  2AEH A;  2DKP A;  2FJU B;  5LG4 B;  3TW1 A;  4QJ5 B;  3VIA A;  1BAK A;  1QQG A;  5JLJ B;  2D11 A;  2QKM A;  1ZSQ A;  2VSZ A;  1FOE A;  4A5K A;  3BJI A;  2YS5 A;  1U5G A;  1WJM A;  2LOX A;  5JHG A;  1MKE A;  1SGH A;  2K8E A;  2V76 A;  4CYE A;  1TJ6 A;  1KI1 B;  2COD A;  3PVL A;  4KVG B;  2XQN M;  2LKO A;  5CLQ B;  1V5M A;  4ZRJ A;  5D3V A;  4EKU A;  2KUP A;  2NMB A;  3A58 A;  4D6W A;  4GNK B;  5HE3 A;  4GMX B;  5M4Y B;  2MDX A;  1I7A A;  2EC1 A;  2DA0 A;  3PG7 A;  1Y19 B;  1FB8 A;  2LUL A;  2D9Z A;  1U2B A;  2DX1 A;  4OSN A;  1GC6 A;  4GN1 A;  5HE1 A;  1UNR A;  2X18 A;  1M7R A;  1J19 A;  4HAV B;  4D0N B;  4QXA B;  2JP2 A;  4CHM A;  2D9W A;  2UZR A;  1BTN A;  2GCL A;  2RSG A;  2VKI A;  3VOQ A;  2DYN A;  1GC7 A;  4CHJ A;  2DTC A;  5FI0 A;  2W2X C;  4GXB A;  4DXA B;  4Z2N A;  3DCX A;  3DXE A;  1V5U A;  3ODO A;  4KAX B;  3BIN A;  1UEF A;  2H7D A;  4XWX A;  4F7G A;  4HDQ A;  2Y7B A;  3A8P A;  3F5R A;  4PQ0 A;  4HAY B;  2N23 A;  5DHF B;  5C16 A;  2YT2 A;  3UZT A;  2GCJ A;  3PEG A;  3AJ4 A;  4Y94 A;  4BBK A;  3OAN A;  5J3Q A;  3V5W A;  1P6S A;  2YT1 A;  2EMS A;  1BTK A;  4HAT B;  2UVM A;  1U5D A;  1H10 A;  3MPX A;  3CXB B;  1FGZ A;  1ZYI A;  2W2W A;  3NWF A;  1W1H A;  3AU4 A;  3PZD A;  3ODW A;  2KIG A;  4GOU A;  1WGU A;  5HE2 A;  2ADZ A;  3P7Z A;  2D2Q A;  2P0F A;  4ZRK A;  1X05 A;  2R09 A;  3F0W A;  1XD4 A;  4HB0 B;  1Z87 A;  4PNK A;  1Y5O A;  2KIE A;  2EJ8 A;  1FHX A;  1AQC A;  1LW3 A;  1DBH A;  1X11 A;  1NTY A;  2DHI A;  4A6H A;  2N0Y A;  4YL8 A;  4A6F B;  3B77 A;  4B6H A;  1MK7 B;  1ZC3 B;  3A98 B;  4HB3 B;  4TKN A;  1X86 A;  2IYB A;  1K5D B;  2R0D A;  3T06 A;  1DRO A;  1OMW A;  3NW8 A;  5FI1 A;  3D8E A;  2RRF A;  1K5G B;  1W1G A;  1QC6 A;  5IRS A;  5KQ1 A;  1EGX A;  2YSZ A;  2CY5 A;  3WYF B;  1Q67 A;  1MAI A;  4HSI A;  3HK0 A;  5I2M A;  2NBV A;  3PP2 A;  3ZVR A;  2M14 A;  2I1K A;  5C79 A;  3QBV B;  3KRW A;  5I2S A;  3TO1 A;  3ULB A;  2GJY A;  2RLO A;  5C5B B;  1UPR A;  2UZS A;  2FJL A;  1OQN A;  2DYQ A;  1U29 A;  1FHO A;  2COC A;  3TFM A;  1T77 A;  1WG7 A;  2KGX B;  1AWE A;  4WVF B;  2D4Q A;  2ELA A;  3FVC A;  5JHH A;  5C6R A;  2OTX A;  2J0M A;  3KRX A;  2KUQ A;  4DX8 A;  2YS1 A;  3NWA A;  3U12 A;  5DH9 B;  4KHB B;  2Z4D A;  1V61 A;  2P8V A;  2D10 A;  1N3H A;  3TCA A;  2Z59 A;  2J0K A;  2Z0O A;  3RCP A;  1KZG A;  4F7U P;  3NSU A;  4MK0 A;  4WSF A;  2DHJ A;  3AU5 A;  5DIF B;  4HHV A;  2I5F A;  1NU2 A;  4K2P A;  2G35 A;  2QKL A;  5D27 A;  2Z0Q A;  1XX0 A;  1UPQ A;  2EMT A;  3DXD A;  5D3X A;  4IFS A;  1PFJ A;  5CLL B;  2LOZ A;  1PLS A;  2RGN B;  3LJU X;  3ULC A;  1P5T A;  2DN6 A;  1KZ7 A;  2MWN B;  1FHW A;  2DFK A;  1MIX A;  3A8Q A;  4EMO A;  2Y8G A;  2AL6 A;  4OT1 A;  5DHA B;  4DIX A;  1PMS A;  4K2O A;  2CY4 A;  4HAW B;  4DBB A;  3ODX A;  2D9V A;  4QJ3 B;  1BWN A;  1XR0 B;  4HAU B;  4WJ7 A;  5J3Y A;  2MKR A;  2ZKM X;  3GYP A;  4A6F A;  3OHM B;  2W2X D;  1TQZ A;  4EJN A;  5LOP B;  3PVU A;  4MT7 A;  1RRP B;  2ROZ B;  2ROV A;  1OY2 A;  4K17 A;  1U27 A;  5D3W A;  5JP4 A;  3HW2 B;  2PZ1 A; 
#chains in the Genus database with same CATH homology
 4P7I A;  1U5F A;  2L2I A;  3X23 A;  1WGQ A;  2YRY A;  3FSS A;  2CRF A;  2DHK A;  1TXD A;  1RJ2 A;  2LG1 A;  3WA0 A;  1WVH A;  2IFS A;  5L81 A;  2VRW B;  3DXC A;  1EAZ A;  1UNP A;  2RUK B;  1FAO A;  4YON A;  1U5E A;  2NZ8 B;  3MDB C;  3D8D A;  1V88 A;  1IRS A;  5C5B A;  4GPT B;  1M7E A;  3CIK A;  5KCV A;  1LB1 A;  3QIJ A;  4ZRI A;  1V89 A;  5KQ4 A;  3SUZ A;  2YF0 A;  2COA A;  1WI1 A;  2HTH B;  2YS3 A;  2Z0P A;  3G9W A;  2RVB B;  4KHA A;  1ISN A;  1DDW A;  4IAP A;  4KHO A;  1NTV A;  5D3Y A;  4HDO A;  1XOD A;  2K2J A;  2COF A;  3SV1 A;  1X1F A;  1E5W A;  3SO6 A;  1XCG A;  2LYD A;  3KZ1 A;  3ML4 A;  5HE0 A;  3TVV A;  2YT0 A;  3PSC A;  1MIZ B;  1J0W A;  2KCJ A;  3SNH A;  2P0D A;  1XKE A;  3ZDT A;  2J59 M;  1P3R A;  2DX5 A;  3N7C A;  2I1J A;  4NSW A;  5EFX A;  3FM8 C;  1FGY A;  2ELB A;  2Q13 A;  5DI9 B;  1SHC A;  1ZM0 A;  1ZC4 B;  1EVH A;  4GZU A;  3P6A A;  4HB4 B;  2E2X A;  1UNQ A;  2HE7 A;  2J0J A;  1DDM A;  1B55 A;  1ZVR A;  2Y8F A;  3O96 A;  4GMV A;  4IOY X;  2DLW A;  1GG3 A;  2K00 A;  2P0H A;  5GOW B;  1H4R A;  4H8S A;  4K81 A;  4DX9 0;  2CAY A;  2BCJ A;  3D8F A;  3IVF A;  3PVW A;  5LON B;  3M1I B;  2M38 A;  1WJ1 A;  2D9X A;  4HAZ B;  2YVC A;  3HQC A;  4HAX B;  1MK9 B;  4NY0 A;  5J3T A;  2RNR B;  3U8Z A;  3SYX A;  4HB2 B;  4TYZ A;  4MY6 A;  4F7H A;  1X1G A;  1DYN A;  3QWM A;  2H7E A;  2OQB A;  4A6K A;  3GYO A;  2DKQ A;  1MPH A;  1V5P A;  2K2U A;  2D9Y A;  1W1D A;  2L1C A;  2MFQ A;  3U7D A;  2ZPY A;  1NI2 A;  3KY9 A;  1DDV A;  4L6E A;  4C0A A;  2I5C A;  3KSY A;  4Z2M B;  1EF1 A;  3FEH A;  1I2H A;  2GS0 A;  2AEH A;  2DKP A;  3TW1 A;  3VIA A;  1BAK A;  1QQG A;  5JLJ B;  2D11 A;  2QKM A;  1ZSQ A;  2VSZ A;  1FOE A;  4A5K A;  3BJI A;  2YS5 A;  1U5G A;  1WJM A;  2LOX A;  5JHG A;  1MKE A;  1SGH A;  2V76 A;  4CYE A;  1TJ6 A;  1KI1 B;  2COD A;  3PVL A;  4KVG B;  2XQN M;  2LKO A;  5CLQ B;  1V5M A;  4ZRJ A;  5D3V A;  4EKU A;  2KUP A;  2NMB A;  5HE3 A;  4GMX B;  2MDX A;  1I7A A;  2EC1 A;  2DA0 A;  3PG7 A;  1Y19 B;  1FB8 A;  2LUL A;  2D9Z A;  1U2B A;  2DX1 A;  1GC6 A;  4GN1 A;  5HE1 A;  1UNR A;  2X18 A;  1M7R A;  1J19 A;  4HAV B;  4D0N B;  2JP2 A;  4CHM A;  2D9W A;  2UZR A;  1BTN A;  2GCL A;  2RSG A;  2VKI A;  3VOQ A;  2DYN A;  1GC7 A;  4CHJ A;  2DTC A;  5FI0 A;  2W2X C;  4GXB A;  4DXA B;  4Z2N A;  3DXE A;  1V5U A;  3ODO A;  4KAX B;  3BIN A;  1UEF A;  2H7D A;  4XWX A;  4F7G A;  4HDQ A;  2Y7B A;  3A8P A;  3F5R A;  4PQ0 A;  4HAY B;  2N23 A;  5DHF B;  5C16 A;  3UZT A;  2GCJ A;  3PEG A;  3AJ4 A;  4Y94 A;  4BBK A;  3OAN A;  5J3Q A;  3V5W A;  1P6S A;  2YT1 A;  2EMS A;  1BTK A;  4HAT B;  2UVM A;  1U5D A;  1H10 A;  3MPX A;  3CXB B;  1FGZ A;  2W2W A;  3PZD A;  1W1H A;  3AU4 A;  3ODW A;  1WGU A;  5HE2 A;  2ADZ A;  3P7Z A;  2D2Q A;  2P0F A;  4ZRK A;  1X05 A;  2R09 A;  3F0W A;  1XD4 A;  4HB0 B;  1Z87 A;  4PNK A;  1Y5O A;  2EJ8 A;  1FHX A;  1AQC A;  1LW3 A;  1DBH A;  1X11 A;  1NTY A;  2DHI A;  4A6H A;  2N0Y A;  4YL8 A;  4A6F B;  4B6H A;  1MK7 B;  1ZC3 B;  3A98 B;  4HB3 B;  4TKN A;  1X86 A;  2IYB A;  1K5D B;  2R0D A;  3T06 A;  1DRO A;  1OMW A;  5FI1 A;  3D8E A;  1K5G B;  1W1G A;  1QC6 A;  5KQ1 A;  1EGX A;  2YSZ A;  2CY5 A;  3WYF B;  1Q67 A;  1MAI A;  3HK0 A;  3PP2 A;  3ZVR A;  2M14 A;  2I1K A;  5C79 A;  3QBV B;  3KRW A;  3TO1 A;  3ULB A;  2GJY A;  2RLO A;  5C5B B;  1UPR A;  2UZS A;  2FJL A;  1OQN A;  2DYQ A;  1U29 A;  1FHO A;  2COC A;  3TFM A;  1WG7 A;  2KGX B;  1AWE A;  4WVF B;  2D4Q A;  2ELA A;  5JHH A;  5C6R A;  2OTX A;  2J0M A;  3KRX A;  4DX8 A;  2YS1 A;  5DH9 B;  4KHB B;  1V61 A;  2P8V A;  2D10 A;  1N3H A;  3TCA A;  2J0K A;  2Z0O A;  3RCP A;  1KZG A;  4F7U P;  3NSU A;  4MK0 A;  4WSF A;  2DHJ A;  3AU5 A;  5DIF B;  4HHV A;  2I5F A;  1NU2 A;  4K2P A;  2G35 A;  2QKL A;  5D27 A;  2Z0Q A;  1XX0 A;  1UPQ A;  2EMT A;  3DXD A;  5D3X A;  4IFS A;  1PFJ A;  5CLL B;  2LOZ A;  1PLS A;  2RGN B;  3LJU X;  3ULC A;  1P5T A;  2DN6 A;  1KZ7 A;  2MWN B;  1FHW A;  2DFK A;  1MIX A;  3A8Q A;  4EMO A;  2Y8G A;  2AL6 A;  5DHA B;  1PMS A;  4K2O A;  2CY4 A;  4HAW B;  4DBB A;  3ODX A;  2D9V A;  1BWN A;  1XR0 B;  4HAU B;  4WJ7 A;  5J3Y A;  2MKR A;  3GYP A;  4A6F A;  2W2X D;  1TQZ A;  4EJN A;  5LOP B;  3PVU A;  4MT7 A;  1RRP B;  2ROZ B;  2ROV A;  1OY2 A;  4K17 A;  1U27 A;  5D3W A;  5JP4 A;  3HW2 B;  2PZ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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