5E66A

The complex structure of hemagglutinin-esterase-fusion mutant protein from the influenza d virus with receptor analog 9-n-ac-sia
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
427
structure length
424
Chain Sequence
ELICIVQRVNESFSLHSGFGGNVYSMKTEPMTGFTNVTKGASVINQKDWIGFGDSRTDLTNDQFPASSDVPLAVAKKFRSLSGASLMLSAFGPPGKVDYLYQGCGKEKVFYEGVNWSPEAGIDCFGSNWTQTKKDFYSRIYEAARSSTCMTLVNSLDTKISSTTATAGTASSCSSSWMKSPLWYAESSVNPPQVCGTEQSATFTLPTSFGIYKCNKHVVQLCYFVYENKAKFNTFGCGDYYQNYYDGNGNLIGGMDNRVAAYRGIANAGVKIECPSKILNPGTYSIKSTPRFLLVPKRSYCFDTDGGYPIQVVQSEWSASRRSDNATEEACLQTEGCIFIKKTTPYVGEADDNHGDIEMRQLLSGLGNNDTVCVSQSGYTKGETPFVKDYLSPPKYGRCQLKTDSGRIPTLPSGLIIPQAGTDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
pubmed doi rcsb
molecule tags Hydrolase
source organism Influenza d virus (d/swine/oklahoma/1334/2011)
molecule keywords Hemagglutinin-esterase
total genus 109
structure length 424
sequence length 427
ec nomenclature
pdb deposition date 2015-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02710 Hema_HEFG Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein
A PF03996 Hema_esterase Hemagglutinin esterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.20 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 5e66A01
5E65A 5E64A 1FLCA 5E5WA 5E62A 5E66A
chains in the Genus database with same CATH superfamily
3KAHA 3L4HA 3MCBB 2DWVA 2JMFA 3KAGA 2DMVA 2ITKA 3LKXB 2ZQUA 5E5WA 2ZR6A 1YW5A 4A0TA 2MDIA 3TDBA 1NMVA 2BA1A 2RE3A 2XP7A 2JV4A 3KADA 4E5RA 5U47A 2LAJA 3KAIA 2DK1A 3KAFA 5E66A 2ZR4A 5E64A 2OWOA 3FSBA 3PQHA 5CQ2A 2ZQSA 2XP8A 2KXQA 2XP6A 2XPAA 3MQGA 3WH0A 2JXWA 1K9RA 2WAEA 2XP9A 1K9QA 2M8IA 3KCEA 2F21A 5AHTA 1F8AB 2ZQTA 1I5HW 2XP5A 2ZAJA 2M8JA 3OOBA 2Y8NB 2XP4A 3NTPA 2YSFA 1TR8A 2XPBA 3LKXA 4U84A 3FS8A 3TC5A 1WR7A 3M85A 2YSBA 3CNGA 4U86A 2EZ5W 5E65A 4A0UA 1O6WA 2DK7A 3MQHA 3FSCA 2ZQVA 1WMVA 3M7NA 1JMQA 1RP5A 4QIBA 2Q5AA 3ODKA 2YAJB 2M3OW 1ZCNA 3LE4A 1EG4A 3MCBA 3TCZA 2JX8A 4GLXA 1PINA 1FLCA 2DJYA 2YSIA 2L4JA 2YSHA 1TK7A 2ZR5A 4REXA 2XP3A 2E45A 2YSGA 4U85A 2WADA 2QRVA 1EG3A 3KABA 5E62A
chains in the Genus database with same CATH topology
3KAHA 3L4HA 3MCBB 2DWVA 2JMFA 3KAGA 2DMVA 2ITKA 3LKXB 2ZQUA 5E5WA 2ZR6A 1YW5A 4A0TA 2MDIA 3TDBA 1NMVA 2BA1A 2RE3A 2XP7A 2JV4A 3KADA 4E5RA 5U47A 2LAJA 3KAIA 2DK1A 3KAFA 5E66A 2ZR4A 5E64A 2OWOA 3FSBA 3PQHA 5CQ2A 2ZQSA 2XP8A 2KXQA 2XP6A 2XPAA 3MQGA 3WH0A 2JXWA 1K9RA 2WAEA 2XP9A 1K9QA 2M8IA 3KCEA 2F21A 5AHTA 1F8AB 2ZQTA 1I5HW 2XP5A 2ZAJA 2M8JA 3OOBA 2Y8NB 2XP4A 3NTPA 2YSFA 1TR8A 2XPBA 3LKXA 4U84A 3FS8A 3TC5A 1WR7A 3M85A 2YSBA 3CNGA 4U86A 2EZ5W 5E65A 4A0UA 1O6WA 2DK7A 3MQHA 3FSCA 2ZQVA 1WMVA 3M7NA 1JMQA 1RP5A 4QIBA 2Q5AA 3ODKA 2YAJB 2M3OW 1ZCNA 3LE4A 1EG4A 3MCBA 3TCZA 2JX8A 4GLXA 1PINA 1FLCA 2DJYA 2YSIA 2L4JA 2YSHA 1TK7A 2ZR5A 4REXA 2XP3A 2E45A 2YSGA 4U85A 2WADA 2QRVA 1EG3A 3KABA 5E62A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E65 A;  5E64 A;  1FLC A;  5E5W A;  5E62 A;  5E66 A; 
#chains in the Genus database with same CATH topology
 3KAH A;  3L4H A;  3MCB B;  2DWV A;  2JMF A;  3KAG A;  2DMV A;  2ITK A;  3LKX B;  2ZQU A;  5E5W A;  2ZR6 A;  1YW5 A;  4A0T A;  2MDI A;  3TDB A;  1NMV A;  2BA1 A;  2RE3 A;  2XP7 A;  2JV4 A;  3KAD A;  4E5R A;  5U47 A;  2LAJ A;  3KAI A;  2DK1 A;  3KAF A;  5E66 A;  2ZR4 A;  5E64 A;  2OWO A;  3FSB A;  3PQH A;  5CQ2 A;  2ZQS A;  2XP8 A;  2KXQ A;  2XP6 A;  2XPA A;  3MQG A;  3WH0 A;  2JXW A;  1K9R A;  2WAE A;  2XP9 A;  1K9Q A;  2M8I A;  3KCE A;  2F21 A;  5AHT A;  1F8A B;  2ZQT A;  1I5H W;  2XP5 A;  2ZAJ A;  2M8J A;  3OOB A;  2Y8N B;  2XP4 A;  3NTP A;  2YSF A;  1TR8 A;  2XPB A;  3LKX A;  4U84 A;  3FS8 A;  3TC5 A;  1WR7 A;  3M85 A;  2YSB A;  3CNG A;  4U86 A;  2EZ5 W;  5E65 A;  4A0U A;  1O6W A;  2DK7 A;  3MQH A;  3FSC A;  2ZQV A;  1WMV A;  3M7N A;  1JMQ A;  1RP5 A;  4QIB A;  2Q5A A;  3ODK A;  2YAJ B;  2M3O W;  1ZCN A;  3LE4 A;  1EG4 A;  3MCB A;  3TCZ A;  2JX8 A;  4GLX A;  1PIN A;  1FLC A;  2DJY A;  2YSI A;  2L4J A;  2YSH A;  1TK7 A;  2ZR5 A;  4REX A;  2XP3 A;  2E45 A;  2YSG A;  4U85 A;  2WAD A;  2QRV A;  1EG3 A;  3KAB A;  5E62 A; 
#chains in the Genus database with same CATH homology
 3KAH A;  3L4H A;  3MCB B;  2DWV A;  2JMF A;  3KAG A;  2DMV A;  2ITK A;  3LKX B;  2ZQU A;  5E5W A;  2ZR6 A;  1YW5 A;  4A0T A;  2MDI A;  3TDB A;  1NMV A;  2BA1 A;  2RE3 A;  2XP7 A;  2JV4 A;  3KAD A;  4E5R A;  5U47 A;  2LAJ A;  3KAI A;  2DK1 A;  3KAF A;  5E66 A;  2ZR4 A;  5E64 A;  2OWO A;  3FSB A;  3PQH A;  5CQ2 A;  2ZQS A;  2XP8 A;  2KXQ A;  2XP6 A;  2XPA A;  3MQG A;  3WH0 A;  2JXW A;  1K9R A;  2WAE A;  2XP9 A;  1K9Q A;  2M8I A;  3KCE A;  2F21 A;  5AHT A;  1F8A B;  2ZQT A;  1I5H W;  2XP5 A;  2ZAJ A;  2M8J A;  3OOB A;  2Y8N B;  2XP4 A;  3NTP A;  2YSF A;  1TR8 A;  2XPB A;  3LKX A;  4U84 A;  3FS8 A;  3TC5 A;  1WR7 A;  3M85 A;  2YSB A;  3CNG A;  4U86 A;  2EZ5 W;  5E65 A;  4A0U A;  1O6W A;  2DK7 A;  3MQH A;  3FSC A;  2ZQV A;  1WMV A;  3M7N A;  1JMQ A;  1RP5 A;  4QIB A;  2Q5A A;  3ODK A;  2YAJ B;  2M3O W;  1ZCN A;  3LE4 A;  1EG4 A;  3MCB A;  3TCZ A;  2JX8 A;  4GLX A;  1PIN A;  1FLC A;  2DJY A;  2YSI A;  2L4J A;  2YSH A;  1TK7 A;  2ZR5 A;  4REX A;  2XP3 A;  2E45 A;  2YSG A;  4U85 A;  2WAD A;  2QRV A;  1EG3 A;  3KAB A;  5E62 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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