5FCFA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and mn bound
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
397
structure length
397
Chain Sequence
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 136
structure length 397
sequence length 397
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fcfA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fcfA02
2Q94A 1WN1A 3TAVA 3CB5A 4U71A 3PKAA 1QZYA 4FLIA 5D6EA 4PNCA 2GGBA 2Q8KA 3I7MA 2Q92A 2BHAA 2BHDA 4ZWPA 1PV9A 3PKEA 2Q96A 2BWSA 2V3XA 2B3LA 1WBQA 3IG4A 3PN9A 5FCFA 1XGSA 4A6WA 4FUKA 1XNZA 4PV4A 1CHMA 3QOCA 1C23A 2GG2A 4IPAA 2Q95A 4FO7A 2NQ7A 2GG9A 1KQ0A 3BITA 4QR8A 4EGEA 2NQ6A 2ZSGA 3IU7A 4JUQA 2BWTA 4ZNGA 2B3HA 2DFIA 2HOWA 4U6WA 3TB5A 2BH3A 5CLSA 1WL6A 1R58A 2GU5A 5JHUA 4IECA 2GG8A 3BIPA 1KP0A 2GG0A 2BWYA 5CE6A 5CIKA 1XGMA 1R5HA 3IU8A 4MATA 2BHCA 2OAZA 5E2CA 1O0XA 2P9AA 4U6JA 2EA2A 3MATA 4FLJA 2MATA 1YVMA 2V6CA 4RZYA 2B3KA 3IU9A 4U70A 1C27A 4B28A 2GA2A 2BWVA 3L7GA 4KM3A 2BN7A 2BWWA 3D27A 2GU7A 2BWUA 4R60A 4FLLA 4S00A 1W2MA 1BN5A 1YJ3A 1QXWA 4U69A 1A16A 3IL0A 5FCHA 1WL9A 4ZWUA 1KQ9A 4FLKA 2EVOA 4IKUA 5D6FA 3OVKA 4S2RP 2GG3A 1B59A 2GU4A 4IDYA 4RZZA 2GU6A 1W7VA 2V3ZA 3CB6A 2EVCA 1N51A 1JAWA 4ZWOA 2P99A 3MX6A 4U6CA 2Q93A 1XGOA 2BB7A 1WKMA 3RORA 1C22A 4U1BA 2GTXA 4IKRA 1YW7A 3FMQA 4U76A 2P98A 5CDEA 4U6ZA 2V3YA 2BWXA 1C21A 1YW9A 2EA4A 3PKDA 4HXXA 3RVAA 3PKCA 5JFRA 3OOOA 1BOAA 4S01A 1R5GA 2GGCA 1WY2A 4RGZ1 5CDLA 2BHBA 3Q6DA 4S2TP 2OKNA 2ADUA 2GG7A 5JI6A 1YW8A 3FM3A 4OOKA 1QXYA 1B6AA 4IU6A 2EVMA 2GZ5A 1C24A 4U6EA 2GG5A 4Z7MA 5CDVA 5E5BA 3FMRA 2IW2A 4FKCA 3L24A 3MR1A 3PKBA 1XGNA 4IKTA 3S6BA 4U75A 4U73A 1WLRA 3CTZA 3PEBA 4FO8A 4A6VA 1QXZA 3O5VA 1M35A 4IF7A 4IKSA 1MATA 1Y1NA 5CNXA 2G6PA 3BIQA
chains in the Genus database with same CATH superfamily
2Q94A 1WN1A 3TAVA 3CB5A 4U71A 3PKAA 1QZYA 4FLIA 5D6EA 4PNCA 2GGBA 2Q8KA 3I7MA 2Q92A 2BHAA 2BHDA 4ZWPA 1PV9A 3PKEA 2Q96A 2BWSA 2V3XA 2B3LA 1WBQA 3IG4A 3PN9A 5FCFA 1XGSA 4A6WA 4FUKA 1XNZA 4PV4A 1CHMA 3QOCA 1C23A 2GG2A 4IPAA 2Q95A 4FO7A 2NQ7A 2GG9A 1KQ0A 3BITA 4QR8A 4EGEA 2NQ6A 2ZSGA 3IU7A 4JUQA 2BWTA 4ZNGA 2B3HA 2DFIA 2HOWA 4U6WA 3TB5A 2BH3A 5CLSA 1WL6A 1R58A 2GU5A 5JHUA 4IECA 2GG8A 3BIPA 1KP0A 2GG0A 2BWYA 5CE6A 5CIKA 1XGMA 1R5HA 3IU8A 4MATA 2BHCA 2OAZA 5E2CA 1O0XA 2P9AA 4U6JA 2EA2A 3MATA 4FLJA 2MATA 1YVMA 2V6CA 4RZYA 2B3KA 3IU9A 4U70A 1C27A 4B28A 2GA2A 2BWVA 3L7GA 4KM3A 2BN7A 2BWWA 3D27A 2GU7A 2BWUA 4R60A 4FLLA 4S00A 1W2MA 1BN5A 1YJ3A 1QXWA 4U69A 1A16A 3IL0A 5FCHA 1WL9A 4ZWUA 1KQ9A 4FLKA 2EVOA 4IKUA 5D6FA 3OVKA 4S2RP 2GG3A 1B59A 2GU4A 4IDYA 4RZZA 2GU6A 1W7VA 2V3ZA 3CB6A 2EVCA 1N51A 1JAWA 4ZWOA 2P99A 3MX6A 4U6CA 2Q93A 1XGOA 2BB7A 1WKMA 3RORA 1C22A 4U1BA 2GTXA 4IKRA 1YW7A 3FMQA 4U76A 2P98A 5CDEA 4U6ZA 2V3YA 2BWXA 1C21A 1YW9A 2EA4A 3PKDA 4HXXA 3RVAA 3PKCA 5JFRA 3OOOA 1BOAA 4S01A 1R5GA 2GGCA 1WY2A 4RGZ1 5CDLA 2BHBA 3Q6DA 4S2TP 2OKNA 2ADUA 2GG7A 5JI6A 1YW8A 3FM3A 4OOKA 1QXYA 1B6AA 4IU6A 2EVMA 2GZ5A 1C24A 4U6EA 2GG5A 4Z7MA 5CDVA 5E5BA 3FMRA 2IW2A 4FKCA 3L24A 3MR1A 3PKBA 1XGNA 4IKTA 3S6BA 4U75A 4U73A 1WLRA 3CTZA 3PEBA 4FO8A 4A6VA 1QXZA 3O5VA 1M35A 4IF7A 4IKSA 1MATA 1Y1NA 5CNXA 2G6PA 3BIQA
chains in the Genus database with same CATH topology
2Q94A 1WN1A 3TAVA 3CB5A 4U71A 3PKAA 1QZYA 4FLIA 5D6EA 4PNCA 2GGBA 2Q8KA 3I7MA 2Q92A 2BHAA 2BHDA 4ZWPA 1PV9A 3PKEA 2Q96A 2BWSA 2V3XA 2B3LA 1WBQA 3IG4A 3PN9A 5FCFA 1XGSA 4A6WA 4FUKA 1XNZA 4PV4A 1CHMA 3QOCA 1C23A 2GG2A 4IPAA 2Q95A 4FO7A 2NQ7A 2GG9A 1KQ0A 3BITA 4QR8A 4EGEA 2NQ6A 2ZSGA 3IU7A 4JUQA 2BWTA 4ZNGA 2B3HA 2DFIA 2HOWA 4U6WA 3TB5A 2BH3A 5CLSA 1WL6A 1R58A 2GU5A 5JHUA 4IECA 2GG8A 3BIPA 1KP0A 2GG0A 2BWYA 5CE6A 5CIKA 1XGMA 1R5HA 3IU8A 4MATA 2BHCA 2OAZA 5E2CA 1O0XA 2P9AA 4U6JA 2EA2A 3MATA 4FLJA 2MATA 1YVMA 2V6CA 4RZYA 2B3KA 3IU9A 4U70A 1C27A 4B28A 2GA2A 2BWVA 3L7GA 4KM3A 2BN7A 2BWWA 3D27A 2GU7A 2BWUA 4R60A 4FLLA 4S00A 1W2MA 1BN5A 1YJ3A 1QXWA 4U69A 1A16A 3IL0A 5FCHA 1WL9A 4ZWUA 1KQ9A 4FLKA 2EVOA 4IKUA 5D6FA 3OVKA 4S2RP 2GG3A 1B59A 2GU4A 4IDYA 4RZZA 2GU6A 1W7VA 2V3ZA 3CB6A 2EVCA 1N51A 1JAWA 4ZWOA 2P99A 3MX6A 4U6CA 2Q93A 1XGOA 2BB7A 1WKMA 3RORA 1C22A 4U1BA 2GTXA 4IKRA 1YW7A 3FMQA 4U76A 2P98A 5CDEA 4U6ZA 2V3YA 2BWXA 1C21A 1YW9A 2EA4A 3PKDA 4HXXA 3RVAA 3PKCA 5JFRA 3OOOA 1BOAA 4S01A 1R5GA 2GGCA 1WY2A 4RGZ1 5CDLA 2BHBA 3Q6DA 4S2TP 2OKNA 2ADUA 2GG7A 5JI6A 1YW8A 3FM3A 4OOKA 1QXYA 1B6AA 4IU6A 2EVMA 2GZ5A 1C24A 4U6EA 2GG5A 4Z7MA 5CDVA 5E5BA 3FMRA 2IW2A 4FKCA 3L24A 3MR1A 3PKBA 1XGNA 4IKTA 3S6BA 4U75A 4U73A 1WLRA 3CTZA 3PEBA 4FO8A 4A6VA 1QXZA 3O5VA 1M35A 4IF7A 4IKSA 1MATA 1Y1NA 5CNXA 2G6PA 3BIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q94 A;  1WN1 A;  3TAV A;  3CB5 A;  4U71 A;  3PKA A;  1QZY A;  4FLI A;  5D6E A;  4PNC A;  2GGB A;  2Q8K A;  3I7M A;  2Q92 A;  2BHA A;  2BHD A;  4ZWP A;  1PV9 A;  3PKE A;  2Q96 A;  2BWS A;  2V3X A;  2B3L A;  1WBQ A;  3IG4 A;  3PN9 A;  5FCF A;  1XGS A;  4A6W A;  4FUK A;  1XNZ A;  4PV4 A;  1CHM A;  3QOC A;  1C23 A;  2GG2 A;  4IPA A;  2Q95 A;  4FO7 A;  2NQ7 A;  2GG9 A;  1KQ0 A;  3BIT A;  4QR8 A;  4EGE A;  2NQ6 A;  2ZSG A;  3IU7 A;  4JUQ A;  2BWT A;  4ZNG A;  2B3H A;  2DFI A;  2HOW A;  4U6W A;  3TB5 A;  2BH3 A;  5CLS A;  1WL6 A;  1R58 A;  2GU5 A;  5JHU A;  4IEC A;  2GG8 A;  3BIP A;  1KP0 A;  2GG0 A;  2BWY A;  5CE6 A;  5CIK A;  1XGM A;  1R5H A;  3IU8 A;  4MAT A;  2BHC A;  2OAZ A;  5E2C A;  1O0X A;  2P9A A;  4U6J A;  2EA2 A;  3MAT A;  4FLJ A;  2MAT A;  1YVM A;  2V6C A;  4RZY A;  2B3K A;  3IU9 A;  4U70 A;  1C27 A;  4B28 A;  2GA2 A;  2BWV A;  3L7G A;  4KM3 A;  2BN7 A;  2BWW A;  3D27 A;  2GU7 A;  2BWU A;  4R60 A;  4FLL A;  4S00 A;  1W2M A;  1BN5 A;  1YJ3 A;  1QXW A;  4U69 A;  1A16 A;  3IL0 A;  5FCH A;  1WL9 A;  4ZWU A;  1KQ9 A;  4FLK A;  2EVO A;  4IKU A;  5D6F A;  3OVK A;  4S2R P;  2GG3 A;  1B59 A;  2GU4 A;  4IDY A;  4RZZ A;  2GU6 A;  1W7V A;  2V3Z A;  3CB6 A;  2EVC A;  1N51 A;  1JAW A;  4ZWO A;  2P99 A;  3MX6 A;  4U6C A;  2Q93 A;  1XGO A;  2BB7 A;  1WKM A;  3ROR A;  1C22 A;  4U1B A;  2GTX A;  4IKR A;  1YW7 A;  3FMQ A;  4U76 A;  2P98 A;  5CDE A;  4U6Z A;  2V3Y A;  2BWX A;  1C21 A;  1YW9 A;  2EA4 A;  3PKD A;  4HXX A;  3RVA A;  3PKC A;  5JFR A;  3OOO A;  1BOA A;  4S01 A;  1R5G A;  2GGC A;  1WY2 A;  4RGZ 1;  5CDL A;  2BHB A;  3Q6D A;  4S2T P;  2OKN A;  2ADU A;  2GG7 A;  5JI6 A;  1YW8 A;  3FM3 A;  4OOK A;  1QXY A;  1B6A A;  4IU6 A;  2EVM A;  2GZ5 A;  1C24 A;  4U6E A;  2GG5 A;  4Z7M A;  5CDV A;  5E5B A;  3FMR A;  2IW2 A;  4FKC A;  3L24 A;  3MR1 A;  3PKB A;  1XGN A;  4IKT A;  3S6B A;  4U75 A;  4U73 A;  1WLR A;  3CTZ A;  3PEB A;  4FO8 A;  4A6V A;  1QXZ A;  3O5V A;  1M35 A;  4IF7 A;  4IKS A;  1MAT A;  1Y1N A;  5CNX A;  2G6P A;  3BIQ A; 
#chains in the Genus database with same CATH topology
 2Q94 A;  1WN1 A;  3TAV A;  3CB5 A;  4U71 A;  3PKA A;  1QZY A;  4FLI A;  5D6E A;  4PNC A;  2GGB A;  2Q8K A;  3I7M A;  2Q92 A;  2BHA A;  2BHD A;  4ZWP A;  1PV9 A;  3PKE A;  2Q96 A;  2BWS A;  2V3X A;  2B3L A;  1WBQ A;  3IG4 A;  3PN9 A;  5FCF A;  1XGS A;  4A6W A;  4FUK A;  1XNZ A;  4PV4 A;  1CHM A;  3QOC A;  1C23 A;  2GG2 A;  4IPA A;  2Q95 A;  4FO7 A;  2NQ7 A;  2GG9 A;  1KQ0 A;  3BIT A;  4QR8 A;  4EGE A;  2NQ6 A;  2ZSG A;  3IU7 A;  4JUQ A;  2BWT A;  4ZNG A;  2B3H A;  2DFI A;  2HOW A;  4U6W A;  3TB5 A;  2BH3 A;  5CLS A;  1WL6 A;  1R58 A;  2GU5 A;  5JHU A;  4IEC A;  2GG8 A;  3BIP A;  1KP0 A;  2GG0 A;  2BWY A;  5CE6 A;  5CIK A;  1XGM A;  1R5H A;  3IU8 A;  4MAT A;  2BHC A;  2OAZ A;  5E2C A;  1O0X A;  2P9A A;  4U6J A;  2EA2 A;  3MAT A;  4FLJ A;  2MAT A;  1YVM A;  2V6C A;  4RZY A;  2B3K A;  3IU9 A;  4U70 A;  1C27 A;  4B28 A;  2GA2 A;  2BWV A;  3L7G A;  4KM3 A;  2BN7 A;  2BWW A;  3D27 A;  2GU7 A;  2BWU A;  4R60 A;  4FLL A;  4S00 A;  1W2M A;  1BN5 A;  1YJ3 A;  1QXW A;  4U69 A;  1A16 A;  3IL0 A;  5FCH A;  1WL9 A;  4ZWU A;  1KQ9 A;  4FLK A;  2EVO A;  4IKU A;  5D6F A;  3OVK A;  4S2R P;  2GG3 A;  1B59 A;  2GU4 A;  4IDY A;  4RZZ A;  2GU6 A;  1W7V A;  2V3Z A;  3CB6 A;  2EVC A;  1N51 A;  1JAW A;  4ZWO A;  2P99 A;  3MX6 A;  4U6C A;  2Q93 A;  1XGO A;  2BB7 A;  1WKM A;  3ROR A;  1C22 A;  4U1B A;  2GTX A;  4IKR A;  1YW7 A;  3FMQ A;  4U76 A;  2P98 A;  5CDE A;  4U6Z A;  2V3Y A;  2BWX A;  1C21 A;  1YW9 A;  2EA4 A;  3PKD A;  4HXX A;  3RVA A;  3PKC A;  5JFR A;  3OOO A;  1BOA A;  4S01 A;  1R5G A;  2GGC A;  1WY2 A;  4RGZ 1;  5CDL A;  2BHB A;  3Q6D A;  4S2T P;  2OKN A;  2ADU A;  2GG7 A;  5JI6 A;  1YW8 A;  3FM3 A;  4OOK A;  1QXY A;  1B6A A;  4IU6 A;  2EVM A;  2GZ5 A;  1C24 A;  4U6E A;  2GG5 A;  4Z7M A;  5CDV A;  5E5B A;  3FMR A;  2IW2 A;  4FKC A;  3L24 A;  3MR1 A;  3PKB A;  1XGN A;  4IKT A;  3S6B A;  4U75 A;  4U73 A;  1WLR A;  3CTZ A;  3PEB A;  4FO8 A;  4A6V A;  1QXZ A;  3O5V A;  1M35 A;  4IF7 A;  4IKS A;  1MAT A;  1Y1N A;  5CNX A;  2G6P A;  3BIQ A; 
#chains in the Genus database with same CATH homology
 2Q94 A;  1WN1 A;  3TAV A;  3CB5 A;  4U71 A;  3PKA A;  1QZY A;  4FLI A;  5D6E A;  4PNC A;  2GGB A;  2Q8K A;  3I7M A;  2Q92 A;  2BHA A;  2BHD A;  4ZWP A;  1PV9 A;  3PKE A;  2Q96 A;  2BWS A;  2V3X A;  2B3L A;  1WBQ A;  3IG4 A;  3PN9 A;  5FCF A;  1XGS A;  4A6W A;  4FUK A;  1XNZ A;  4PV4 A;  1CHM A;  3QOC A;  1C23 A;  2GG2 A;  4IPA A;  2Q95 A;  4FO7 A;  2NQ7 A;  2GG9 A;  1KQ0 A;  3BIT A;  4QR8 A;  4EGE A;  2NQ6 A;  2ZSG A;  3IU7 A;  4JUQ A;  2BWT A;  4ZNG A;  2B3H A;  2DFI A;  2HOW A;  4U6W A;  3TB5 A;  2BH3 A;  5CLS A;  1WL6 A;  1R58 A;  2GU5 A;  5JHU A;  4IEC A;  2GG8 A;  3BIP A;  1KP0 A;  2GG0 A;  2BWY A;  5CE6 A;  5CIK A;  1XGM A;  1R5H A;  3IU8 A;  4MAT A;  2BHC A;  2OAZ A;  5E2C A;  1O0X A;  2P9A A;  4U6J A;  2EA2 A;  3MAT A;  4FLJ A;  2MAT A;  1YVM A;  2V6C A;  4RZY A;  2B3K A;  3IU9 A;  4U70 A;  1C27 A;  4B28 A;  2GA2 A;  2BWV A;  3L7G A;  4KM3 A;  2BN7 A;  2BWW A;  3D27 A;  2GU7 A;  2BWU A;  4R60 A;  4FLL A;  4S00 A;  1W2M A;  1BN5 A;  1YJ3 A;  1QXW A;  4U69 A;  1A16 A;  3IL0 A;  5FCH A;  1WL9 A;  4ZWU A;  1KQ9 A;  4FLK A;  2EVO A;  4IKU A;  5D6F A;  3OVK A;  4S2R P;  2GG3 A;  1B59 A;  2GU4 A;  4IDY A;  4RZZ A;  2GU6 A;  1W7V A;  2V3Z A;  3CB6 A;  2EVC A;  1N51 A;  1JAW A;  4ZWO A;  2P99 A;  3MX6 A;  4U6C A;  2Q93 A;  1XGO A;  2BB7 A;  1WKM A;  3ROR A;  1C22 A;  4U1B A;  2GTX A;  4IKR A;  1YW7 A;  3FMQ A;  4U76 A;  2P98 A;  5CDE A;  4U6Z A;  2V3Y A;  2BWX A;  1C21 A;  1YW9 A;  2EA4 A;  3PKD A;  4HXX A;  3RVA A;  3PKC A;  5JFR A;  3OOO A;  1BOA A;  4S01 A;  1R5G A;  2GGC A;  1WY2 A;  4RGZ 1;  5CDL A;  2BHB A;  3Q6D A;  4S2T P;  2OKN A;  2ADU A;  2GG7 A;  5JI6 A;  1YW8 A;  3FM3 A;  4OOK A;  1QXY A;  1B6A A;  4IU6 A;  2EVM A;  2GZ5 A;  1C24 A;  4U6E A;  2GG5 A;  4Z7M A;  5CDV A;  5E5B A;  3FMR A;  2IW2 A;  4FKC A;  3L24 A;  3MR1 A;  3PKB A;  1XGN A;  4IKT A;  3S6B A;  4U75 A;  4U73 A;  1WLR A;  3CTZ A;  3PEB A;  4FO8 A;  4A6V A;  1QXZ A;  3O5V A;  1M35 A;  4IF7 A;  4IKS A;  1MAT A;  1Y1N A;  5CNX A;  2G6P A;  3BIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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