5GO1A

Structural, functional characterization and discovery of novel inhibitors of leishmania amazonensis nucleoside diphosphatase kinase (ndk)
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
138
structure length
112
Chain Sequence
SERTFIAVKPDGVQRGLAGEVICRFERKGYKLVALKMLQPSGPIVCMVWEGKNVVKGGRMLLGATNPADSHPGTIRGDFAVDMGRNVCHGSDSVESAEREIAFWFKADELAC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Nucleoside diphosphate kinase
publication title Discovery of novel inhibitors for Leishmania nucleoside diphosphatase kinase (NDK) based on its structural and functional characterization.
pubmed doi rcsb
source organism Leishmania amazonensis
total genus 27
structure length 112
sequence length 138
ec nomenclature ec 2.7.4.6: Nucleoside-diphosphate kinase.
pdb deposition date 2016-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00334 NDK Nucleoside diphosphate kinase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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