5HDEA

Crystal structure of ptpn12 catalytic domain
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
300
structure length
299
Chain Sequence
EQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of PTPN12 Catalytic Domain
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 12
total genus 108
structure length 299
sequence length 300
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5hdeA00
2NT2A 3D44A 1BZCA 2F6FA 3MOWA 3V0HA 4GE5A 4GFVA 1KAVA 1NL9A 2NV5A 4WOHA 2BV5A 4ZRTA 4NYHA 4OHHA 1GWZA 2QBSA 2B4SA 4QAHA 4H1OA 2MBCA 3EZZA 4D3RA 2I6JA 5BZZA 1M3GA 4GRYA 1SUGA 1ZC0A 4J51A 2CJZA 5KA9A 1P15A 1Q6SA 3N0AA 3RO1A 3D1OA 2VEYA 2GP0A 1G1FA 3S3FA 2JJDA 4BPCA 4I8NA 4JNBA 4AZ1A 3F9BA 4YR8B 4PVGA 1MKPA 2F6VA 2I4GA 2QDMA 3ZM2A 3D9CA 1Q6PA 3U96A 1FQ1A 4PYHA 1EENA 1Q1MA 4Z6BA 4BJOA 4Y2EA 1PTTA 2ZN7A 5BZXA 1Q6NA 2A3KA 2QDPA 3ZMPA 2J17A 5K9WA 1KAKA 5K9VA 1WAXA 2I42A 3BLUA 4TVVA 3BRHA 5EHPA 4GRZA 2OOQA 2CMCA 2B07A 3O4UA 1RPMA 1T49A 1XRIA 2VEVA 2RF6A 1PYNA 4R30A 2I4HA 5AWXA 1OESA 2CMBA 2HNPA 5BX1A 4OHEA 2QBPA 1YTSA 2CM7A 2CNEA 2H4VA 1U26A 4NWFA 1EEOA 2OZ5A 1G4WR 3M4UA 3SR9A 1J4XA 1ECVA 1ZZWA 2FJMA 3CWEA 1C86A 2QEPA 2QDCA 1YWFA 1Q6MA 4KI9A 3OMHA 2E0TA 1I57A 3V0GA 2F6WA 1I9SA 3LJ8A 4OHLA 2HC1A 1C87A 1JF7A 5K22A 1I9TA 1L8GA 1A5YA 1NZ7A 1PA9A 3QCEA 5KA2A 2BGEA 3GXHA 4HJQA 2I4EA 4S0GA 4QBEA 2B4OA 2CNIA 2H03A 4D3QA 1T4JA 1C84A 1YTWA 2HB1A 3F41A 2J16A 2CNFA 2DXPA 5J8RA 2GJTA 3QCBA 1GFYA 2G59A 2PI7A 5I6VA 3QCFA 3V0JA 3MOZA 1U24A 2BZLA 2YDUA 2PBNA 5KAAA 3I80A 2I6PA 1YGRA 1C83A 3RZ2A 1QZ0A 4ZI4A 3D1HA 4ZN5A 4Y14A 5KA3A 3EMUA 2B4UA 3EB1A 1OEVA 2CM8A 2QBQA 4HRFA 2HXPA 2FJNA 2C46A 3O4SA 5KA4A 3S3HA 2BIJA 4RHGA 5LXQB 1PTVA 1YGUA 2PA5A 1LARA 4ICZA 4RI4A 1JLNA 4WTYA 2VEUA 4JMKA 5KA8A 1WRMA 3SMEA 1U25A 2B4PA 5IBMA 1Q6TA 1NO6A 3PS5A 3QCGA 3NMEA 3ZV2A 3A5JA 1L8KA 2H4KA 2I3UA 1LYVA 1YN9A 2J16B 4OHDA 1G7FA 3AWFA 2CFVA 4RI5A 4JBCA 5MMZB 4QUNA 3QCCA 3V0FA 2I6IA 2QCJA 1G1GA 4YAAA 2HY3A 1R6HA 4H34A 4RDDA 1PTUA 3A5KA 2NTAA 3S4EA 2P4DA 1NNYA 2Q05A 3RGQA 3F9AA 2F70A 3OLRA 2Y2FA 4B04A 2PT0A 2CNGA 3QCLA 5KA0A 4IKCA 1NWEA 1ONZA 3D1QA 3BLTA 5K23A 2HVLA 3ZMQA 5K24A 1Q6JA 2PQ5A 3V0IA 1PH0A 3QCKA 4JMJA 3I7ZA 4GWFA 4QUMA 3ZM3A 2I1YA 3B7OA 2ESBA 2OUDA 3QCHA 4KYQA 1OHCA 1PA1A 2VEXA 4HJPA 1YTNA 3S3KA 2NLKA 5KACA 1PXHA 1OHEA 4NWGA 3EAXA 1T48A 3O3LA 1WCHA 3S3EA 3RGOA 2F71A 1OHDA 4DGXA 2SHPA 2HC2A 2G6ZA 1AAXA 2WGPA 3F99A 4GE2A 1V3AA 1RXDA 2PSZA 1FPRA 2VEWA 3ZM1A 2Q47A 1XBOA 3QCDA 2NZ6A 3H2XA 4WU3A 1D5RA 2H4GA 1ZCKA 2CNHA 5IBSA 5KADA 4RH9A 2AHSA 3O4TA 2H04A 1C85A 5M43A 3GXGA 1G4US 1YZ4A 1NWLA 4NX8A 2M3VA 2FH7A 1LQFA 2OC3A 2F6TA 2I75A 4DGPA 2I5XA 4ERCA 4GE6A 5HDEA 1G7GA 2IMGA 1C88A 1G1HA 4WU2A 1ZCLA 1YPTA 4R0SA 4R0TA 1QXKA 3EU0A 5GTJA 2CMAA 2HNQA 3O5XA 3QCNA 2QBRA 3QKPA 5KABA 2HCMA 2B3OA 4GFUA 3F81A 1XM2A 1YFOA 2F6ZA 2QCTA 1X24A 1OEMX 3MMJA 3V0DA 4RKKA 1XXVA 3QCMA 3QCJA 2I3RA 3D42A 3V0EA 2CM3A 2F46A 5BUGA 2Y96A 3QKQA 2R0BA 4RH5A 5KA1A 4NNDA 1FPZA 2A8BA 3CM3A 2H02A 1OEUA 1BZJA 2I6MA 2BGDA 5KA7A 2NT7A 3BM8A 4GS0A 3I36A 3S4OA 1OEOX 1XXPA 2B49A 2AZRA 2P6XA 4MBBA 3QCIA 2F6YA 4OHIA 1OETA 4D3PA 2C7SA 1VHRA 4QAPA 5EHRA 2CM2A 4KYRA 1PTYA 4QBWA 2ZMMA 1ONYA 2GWOA 5K25A 2I6OA 3AWEA 1BZHA 3AWGA 3ZM0A
chains in the Genus database with same CATH superfamily
2NT2A 3D44A 1BZCA 2F6FA 3MOWA 3V0HA 4GE5A 4GFVA 1KAVA 1NL9A 2NV5A 4WOHA 2BV5A 4ZRTA 4NYHA 4OHHA 1GWZA 2QBSA 2B4SA 4QAHA 4H1OA 2MBCA 2VORA 3EZZA 4D3RA 2I6JA 5BZZA 1M3GA 4GRYA 1GQQA 1SUGA 1ZC0A 4J51A 2CJZA 5KA9A 1P15A 1Q6SA 3N0AA 3RO1A 3D1OA 2VEYA 2GP0A 3PYZA 1G1FA 3S3FA 2JJDA 4BPCA 4I8NA 4JNBA 4AZ1A 3F9BA 4YR8B 4PVGA 1MKPA 2F6VA 2GCAA 2I4GA 2QDMA 3ZM2A 3D9CA 1Q6PA 3U96A 1FQ1A 4PYHA 1EENA 4ZIYA 1Q1MA 1E0DA 4HV4A 4Z6BA 4BJOA 4Y2EA 1PTTA 2ZN7A 5BZXA 1Q6NA 2A3KA 2QDPA 2GC6A 3ZMPA 2J17A 5K9WA 1KAKA 5K9VA 1WAXA 2JFHA 2I42A 3BLUA 4TVVA 3BRHA 5EHPA 2VTEA 4GRZA 2OOQA 2CMCA 2B07A 3O4UA 1RPMA 1T49A 1XRIA 2VOSA 2VEVA 2RF6A 1PYNA 4R30A 2I4HA 2GCBA 5AWXA 1OESA 2CMBA 1E8CA 2HNPA 5BX1A 4OHEA 2QBPA 1YTSA 2CM7A 2CNEA 2H4VA 1U26A 4NWFA 2Y68A 1GQYA 1EEOA 2UUPA 2OZ5A 1G4WR 3M4UA 3SR9A 1J4XA 4CVKA 1ECVA 1ZZWA 2FJMA 3CWEA 1C86A 2QEPA 2QDCA 1YWFA 1Q6MA 4KI9A 3OMHA 2E0TA 1I57A 3V0GA 2F6WA 1I9SA 3LJ8A 3ZM5A 4OHLA 2JFGA 2HC1A 1C87A 1JF7A 5K22A 1I9TA 1L8GA 1A5YA 1NZ7A 1PA9A 3QCEA 2Y66A 4BUBA 5KA2A 2BGEA 3GXHA 4HJQA 2I4EA 1P31A 2UUOA 4S0GA 4QBEA 2B4OA 2CNIA 2H03A 4D3QA 1T4JA 1C84A 1YTWA 2HB1A 3F41A 2J16A 2CNFA 2DXPA 5J8RA 2GJTA 3QCBA 1GFYA 2G59A 2PI7A 5I6VA 4QF5A 3QCFA 3V0JA 3MOZA 1U24A 2BZLA 2YDUA 2PBNA 2X5OA 5KAAA 3I80A 2I6PA 1YGRA 1C83A 3RZ2A 1QZ0A 4ZI4A 3D1HA 4ZN5A 3LK7A 2WJPA 4Y14A 5KA3A 3EMUA 2B4UA 3EB1A 1OEVA 2CM8A 2QBQA 4HRFA 2HXPA 2FJNA 2C46A 1W78A 3O4SA 5KA4A 3S3HA 2BIJA 4RHGA 5LXQB 4QDIA 1PTVA 1YGUA 2PA5A 1LARA 4ICZA 4RI4A 1JLNA 4WTYA 2VEUA 4JMKA 5KA8A 1WRMA 1P3DA 1U25A 2B4PA 3SMEA 5IBMA 1Q6TA 1NO6A 3PS5A 1JBVA 3QCGA 2F00A 3NMEA 3ZV2A 3A5JA 1L8KA 2H4KA 2I3UA 1LYVA 1YN9A 2J16B 4OHDA 1G7FA 3AWFA 2CFVA 4RI5A 4JBCA 5MMZB 4QUNA 3QCCA 3V0FA 3ZM6A 2I6IA 2QCJA 1G1GA 4YAAA 2HY3A 1R6HA 4H34A 4RDDA 1PTUA 3A5KA 2NTAA 2Y67A 2P4DA 3S4EA 1NNYA 2Q05A 3RGQA 2GC5A 1JBWA 3F9AA 2F70A 3OLRA 2Y2FA 4B04A 2PT0A 2CNGA 3QCLA 5KA0A 4IKCA 1NWEA 1ONZA 3D1QA 3BLTA 5K23A 2HVLA 3ZMQA 3MVNA 5K24A 1Q6JA 2PQ5A 3V0IA 1PH0A 3QCKA 2VTDA 4JMJA 3I7ZA 4GWFA 4QUMA 3ZM3A 2I1YA 3B7OA 2ESBA 2OUDA 3QCHA 5A5FA 4KYQA 1OHCA 1PA1A 2VEXA 4HJPA 1YTNA 3S3KA 2NLKA 5KACA 1PXHA 1OHEA 4NWGA 4C12A 3EAXA 1W7KA 1T48A 3O3LA 1WCHA 3S3EA 3RGOA 2F71A 1OHDA 4DGXA 4CVLA 2SHPA 2UAGA 2HC2A 2G6ZA 1AAXA 2WGPA 2AM2A 1FGSA 3F99A 4GE2A 1V3AA 1RXDA 2PSZA 1FPRA 2VEWA 3HN7A 3ZM1A 2Q47A 2XJAA 1XBOA 2NZ6A 3H2XA 3QCDA 4WU3A 1D5RA 2H4GA 1ZCKA 2CNHA 3QCZA 5IBSA 5KADA 4RH9A 2AHSA 3O4TA 2H04A 1C85A 5M43A 3GXGA 1G4US 1YZ4A 1NWLA 4UAGA 4NX8A 2M3VA 2FH7A 1LQFA 2OC3A 2F6TA 2I75A 4DGPA 2I5XA 4ERCA 4GE6A 5HDEA 1G7GA 2IMGA 1C88A 1G1HA 1EEHA 4WU2A 1ZCLA 1YPTA 4R0SA 4R0TA 1QXKA 3EU0A 5GTJA 2CMAA 2HNQA 3O5XA 3QCNA 2QBRA 3QKPA 5KABA 2HCMA 1GG4A 2B3OA 4GFUA 3F81A 1XM2A 1YFOA 1O5ZA 2F6ZA 2QCTA 1X24A 1OEMX 3MMJA 2XPCA 3V0DA 4BUCA 4RKKA 1XXVA 3QCMA 3QCJA 2I3RA 3D42A 3V0EA 2CM3A 2F46A 5BUGA 3NRSA 2Y96A 2AM1A 2WTZA 3QKQA 1J6UA 2R0BA 2JFFA 3ZL8A 4RH5A 5KA1A 4NNDA 1FPZA 2A8BA 3CM3A 2H02A 4CVMA 3UAGA 1OEUA 1BZJA 2I6MA 2BGDA 5KA7A 2NT7A 3BM8A 4GS0A 3I36A 3S4OA 1OEOX 1XXPA 2B49A 2AZRA 1UAGA 2P6XA 4MBBA 3QCIA 2F6YA 4OHIA 1OETA 4D3PA 2C7SA 1VHRA 4QAPA 5EHRA 2CM2A 4KYRA 1PTYA 4QBWA 2ZMMA 1ONYA 2GWOA 3N2AA 2Y1OA 5A5EA 5K25A 2I6OA 3AWEA 1BZHA 4C13A 3AWGA 3ZM0A
chains in the Genus database with same CATH topology
2NT2A 3D44A 1BZCA 2F6FA 3MOWA 3V0HA 4GE5A 4GFVA 1KAVA 1NL9A 2NV5A 4WOHA 2BV5A 4ZRTA 4NYHA 4OHHA 1GWZA 2QBSA 2B4SA 4QAHA 4H1OA 2MBCA 3EZZA 4D3RA 2I6JA 5BZZA 1M3GA 4GRYA 1SUGA 1ZC0A 4J51A 2CJZA 5KA9A 1P15A 1Q6SA 3N0AA 3RO1A 3D1OA 2VEYA 2GP0A 1G1FA 3S3FA 2JJDA 4BPCA 4I8NA 4JNBA 4AZ1A 3F9BA 4YR8B 4PVGA 1MKPA 2F6VA 2I4GA 2QDMA 3ZM2A 3D9CA 1Q6PA 3U96A 1FQ1A 4PYHA 1EENA 1Q1MA 4Z6BA 4BJOA 4Y2EA 1PTTA 2ZN7A 5BZXA 1Q6NA 2A3KA 2QDPA 3ZMPA 2J17A 5K9WA 1KAKA 5K9VA 1WAXA 2I42A 3BLUA 4TVVA 3BRHA 5EHPA 4GRZA 2OOQA 2CMCA 2B07A 3O4UA 1RPMA 1T49A 1XRIA 2VEVA 2RF6A 1PYNA 4R30A 2I4HA 5AWXA 1OESA 2CMBA 2HNPA 5BX1A 4OHEA 2QBPA 1YTSA 2CM7A 2CNEA 2H4VA 1U26A 4NWFA 1EEOA 2OZ5A 1G4WR 3M4UA 3SR9A 1J4XA 1ECVA 1ZZWA 2FJMA 3CWEA 1C86A 2QEPA 2QDCA 1YWFA 1Q6MA 4KI9A 3OMHA 2E0TA 1I57A 3V0GA 2F6WA 1I9SA 3LJ8A 4OHLA 2HC1A 1C87A 1JF7A 5K22A 1I9TA 1L8GA 1A5YA 1NZ7A 1PA9A 3QCEA 5KA2A 2BGEA 3GXHA 4HJQA 2I4EA 4S0GA 4QBEA 2B4OA 2CNIA 2H03A 4D3QA 1T4JA 1C84A 1YTWA 2HB1A 3F41A 2J16A 2CNFA 2DXPA 5J8RA 2GJTA 3QCBA 1GFYA 2G59A 2PI7A 5I6VA 3QCFA 3V0JA 3MOZA 1U24A 2BZLA 2YDUA 2PBNA 5KAAA 3I80A 2I6PA 1YGRA 1C83A 3RZ2A 1QZ0A 4ZI4A 3D1HA 4ZN5A 4Y14A 5KA3A 3EMUA 2B4UA 3EB1A 1OEVA 2CM8A 2QBQA 4HRFA 2HXPA 2FJNA 2C46A 3O4SA 5KA4A 3S3HA 2BIJA 4RHGA 5LXQB 1PTVA 1YGUA 2PA5A 1LARA 4ICZA 4RI4A 1JLNA 4WTYA 2VEUA 4JMKA 5KA8A 1WRMA 3SMEA 1U25A 2B4PA 5IBMA 1Q6TA 1NO6A 3PS5A 3QCGA 3NMEA 3ZV2A 3A5JA 1L8KA 2H4KA 2I3UA 1LYVA 1YN9A 2J16B 4OHDA 1G7FA 3AWFA 2CFVA 4RI5A 4JBCA 5MMZB 4QUNA 3QCCA 3V0FA 2I6IA 2QCJA 1G1GA 4YAAA 2HY3A 1R6HA 4H34A 4RDDA 1PTUA 3A5KA 2NTAA 3S4EA 2P4DA 1NNYA 2Q05A 3RGQA 3F9AA 2F70A 3OLRA 2Y2FA 4B04A 2PT0A 2CNGA 3QCLA 5KA0A 4IKCA 1NWEA 1ONZA 3D1QA 3BLTA 5K23A 2HVLA 3ZMQA 5K24A 1Q6JA 2PQ5A 3V0IA 1PH0A 3QCKA 4JMJA 3I7ZA 4GWFA 4QUMA 3ZM3A 2I1YA 3B7OA 2ESBA 2OUDA 3QCHA 4KYQA 1OHCA 1PA1A 2VEXA 4HJPA 1YTNA 3S3KA 2NLKA 5KACA 1PXHA 1OHEA 4NWGA 3EAXA 1T48A 3O3LA 1WCHA 3S3EA 3RGOA 2F71A 1OHDA 4DGXA 2SHPA 2HC2A 2G6ZA 1AAXA 2WGPA 3F99A 4GE2A 1V3AA 1RXDA 2PSZA 1FPRA 2VEWA 3ZM1A 2Q47A 1XBOA 3QCDA 2NZ6A 3H2XA 4WU3A 1D5RA 2H4GA 1ZCKA 2CNHA 5IBSA 5KADA 4RH9A 2AHSA 3O4TA 2H04A 1C85A 5M43A 3GXGA 1G4US 1YZ4A 1NWLA 4NX8A 2M3VA 2FH7A 1LQFA 2OC3A 2F6TA 2I75A 4DGPA 2I5XA 4ERCA 4GE6A 5HDEA 1G7GA 2IMGA 1C88A 1G1HA 4WU2A 1ZCLA 1YPTA 4R0SA 4R0TA 1QXKA 3EU0A 5GTJA 2CMAA 2HNQA 3O5XA 3QCNA 2QBRA 3QKPA 5KABA 2HCMA 2B3OA 4GFUA 3F81A 1XM2A 1YFOA 2F6ZA 2QCTA 1X24A 1OEMX 3MMJA 3V0DA 4RKKA 1XXVA 3QCMA 3QCJA 2I3RA 3D42A 3V0EA 2CM3A 2F46A 5BUGA 2Y96A 3QKQA 2R0BA 4RH5A 5KA1A 4NNDA 1FPZA 2A8BA 3CM3A 2H02A 1OEUA 1BZJA 2I6MA 2BGDA 5KA7A 2NT7A 3BM8A 4GS0A 3I36A 3S4OA 1OEOX 1XXPA 2B49A 2AZRA 2P6XA 4MBBA 3QCIA 2F6YA 4OHIA 1OETA 4D3PA 2C7SA 1VHRA 4QAPA 5EHRA 2CM2A 4KYRA 1PTYA 4QBWA 2ZMMA 1ONYA 2GWOA 5K25A 2I6OA 3AWEA 1BZHA 3AWGA 3ZM0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NT2 A;  3D44 A;  1BZC A;  2F6F A;  3MOW A;  3V0H A;  4GE5 A;  4GFV A;  1KAV A;  1NL9 A;  2NV5 A;  4WOH A;  2BV5 A;  4ZRT A;  4NYH A;  4OHH A;  1GWZ A;  2QBS A;  2B4S A;  4QAH A;  4H1O A;  2MBC A;  3EZZ A;  4D3R A;  2I6J A;  5BZZ A;  1M3G A;  4GRY A;  1SUG A;  1ZC0 A;  4J51 A;  2CJZ A;  5KA9 A;  1P15 A;  1Q6S A;  3N0A A;  3RO1 A;  3D1O A;  2VEY A;  2GP0 A;  1G1F A;  3S3F A;  2JJD A;  4BPC A;  4I8N A;  4JNB A;  4AZ1 A;  3F9B A;  4YR8 B;  4PVG A;  1MKP A;  2F6V A;  2I4G A;  2QDM A;  3ZM2 A;  3D9C A;  1Q6P A;  3U96 A;  1FQ1 A;  4PYH A;  1EEN A;  1Q1M A;  4Z6B A;  4BJO A;  4Y2E A;  1PTT A;  2ZN7 A;  5BZX A;  1Q6N A;  2A3K A;  2QDP A;  3ZMP A;  2J17 A;  5K9W A;  1KAK A;  5K9V A;  1WAX A;  2I42 A;  3BLU A;  4TVV A;  3BRH A;  5EHP A;  4GRZ A;  2OOQ A;  2CMC A;  2B07 A;  3O4U A;  1RPM A;  1T49 A;  1XRI A;  2VEV A;  2RF6 A;  1PYN A;  4R30 A;  2I4H A;  5AWX A;  1OES A;  2CMB A;  2HNP A;  5BX1 A;  4OHE A;  2QBP A;  1YTS A;  2CM7 A;  2CNE A;  2H4V A;  1U26 A;  4NWF A;  1EEO A;  2OZ5 A;  1G4W R;  3M4U A;  3SR9 A;  1J4X A;  1ECV A;  1ZZW A;  2FJM A;  3CWE A;  1C86 A;  2QEP A;  2QDC A;  1YWF A;  1Q6M A;  4KI9 A;  3OMH A;  2E0T A;  1I57 A;  3V0G A;  2F6W A;  1I9S A;  3LJ8 A;  4OHL A;  2HC1 A;  1C87 A;  1JF7 A;  5K22 A;  1I9T A;  1L8G A;  1A5Y A;  1NZ7 A;  1PA9 A;  3QCE A;  5KA2 A;  2BGE A;  3GXH A;  4HJQ A;  2I4E A;  4S0G A;  4QBE A;  2B4O A;  2CNI A;  2H03 A;  4D3Q A;  1T4J A;  1C84 A;  1YTW A;  2HB1 A;  3F41 A;  2J16 A;  2CNF A;  2DXP A;  5J8R A;  2GJT A;  3QCB A;  1GFY A;  2G59 A;  2PI7 A;  5I6V A;  3QCF A;  3V0J A;  3MOZ A;  1U24 A;  2BZL A;  2YDU A;  2PBN A;  5KAA A;  3I80 A;  2I6P A;  1YGR A;  1C83 A;  3RZ2 A;  1QZ0 A;  4ZI4 A;  3D1H A;  4ZN5 A;  4Y14 A;  5KA3 A;  3EMU A;  2B4U A;  3EB1 A;  1OEV A;  2CM8 A;  2QBQ A;  4HRF A;  2HXP A;  2FJN A;  2C46 A;  3O4S A;  5KA4 A;  3S3H A;  2BIJ A;  4RHG A;  5LXQ B;  1PTV A;  1YGU A;  2PA5 A;  1LAR A;  4ICZ A;  4RI4 A;  1JLN A;  4WTY A;  2VEU A;  4JMK A;  5KA8 A;  1WRM A;  3SME A;  1U25 A;  2B4P A;  5IBM A;  1Q6T A;  1NO6 A;  3PS5 A;  3QCG A;  3NME A;  3ZV2 A;  3A5J A;  1L8K A;  2H4K A;  2I3U A;  1LYV A;  1YN9 A;  2J16 B;  4OHD A;  1G7F A;  3AWF A;  2CFV A;  4RI5 A;  4JBC A;  5MMZ B;  4QUN A;  3QCC A;  3V0F A;  2I6I A;  2QCJ A;  1G1G A;  4YAA A;  2HY3 A;  1R6H A;  4H34 A;  4RDD A;  1PTU A;  3A5K A;  2NTA A;  3S4E A;  2P4D A;  1NNY A;  2Q05 A;  3RGQ A;  3F9A A;  2F70 A;  3OLR A;  2Y2F A;  4B04 A;  2PT0 A;  2CNG A;  3QCL A;  5KA0 A;  4IKC A;  1NWE A;  1ONZ A;  3D1Q A;  3BLT A;  5K23 A;  2HVL A;  3ZMQ A;  5K24 A;  1Q6J A;  2PQ5 A;  3V0I A;  1PH0 A;  3QCK A;  4JMJ A;  3I7Z A;  4GWF A;  4QUM A;  3ZM3 A;  2I1Y A;  3B7O A;  2ESB A;  2OUD A;  3QCH A;  4KYQ A;  1OHC A;  1PA1 A;  2VEX A;  4HJP A;  1YTN A;  3S3K A;  2NLK A;  5KAC A;  1PXH A;  1OHE A;  4NWG A;  3EAX A;  1T48 A;  3O3L A;  1WCH A;  3S3E A;  3RGO A;  2F71 A;  1OHD A;  4DGX A;  2SHP A;  2HC2 A;  2G6Z A;  1AAX A;  2WGP A;  3F99 A;  4GE2 A;  1V3A A;  1RXD A;  2PSZ A;  1FPR A;  2VEW A;  3ZM1 A;  2Q47 A;  1XBO A;  3QCD A;  2NZ6 A;  3H2X A;  4WU3 A;  1D5R A;  2H4G A;  1ZCK A;  2CNH A;  5IBS A;  5KAD A;  4RH9 A;  2AHS A;  3O4T A;  2H04 A;  1C85 A;  5M43 A;  3GXG A;  1G4U S;  1YZ4 A;  1NWL A;  4NX8 A;  2M3V A;  2FH7 A;  1LQF A;  2OC3 A;  2F6T A;  2I75 A;  4DGP A;  2I5X A;  4ERC A;  4GE6 A;  5HDE A;  1G7G A;  2IMG A;  1C88 A;  1G1H A;  4WU2 A;  1ZCL A;  1YPT A;  4R0S A;  4R0T A;  1QXK A;  3EU0 A;  5GTJ A;  2CMA A;  2HNQ A;  3O5X A;  3QCN A;  2QBR A;  3QKP A;  5KAB A;  2HCM A;  2B3O A;  4GFU A;  3F81 A;  1XM2 A;  1YFO A;  2F6Z A;  2QCT A;  1X24 A;  1OEM X;  3MMJ A;  3V0D A;  4RKK A;  1XXV A;  3QCM A;  3QCJ A;  2I3R A;  3D42 A;  3V0E A;  2CM3 A;  2F46 A;  5BUG A;  2Y96 A;  3QKQ A;  2R0B A;  4RH5 A;  5KA1 A;  4NND A;  1FPZ A;  2A8B A;  3CM3 A;  2H02 A;  1OEU A;  1BZJ A;  2I6M A;  2BGD A;  5KA7 A;  2NT7 A;  3BM8 A;  4GS0 A;  3I36 A;  3S4O A;  1OEO X;  1XXP A;  2B49 A;  2AZR A;  2P6X A;  4MBB A;  3QCI A;  2F6Y A;  4OHI A;  1OET A;  4D3P A;  2C7S A;  1VHR A;  4QAP A;  5EHR A;  2CM2 A;  4KYR A;  1PTY A;  4QBW A;  2ZMM A;  1ONY A;  2GWO A;  5K25 A;  2I6O A;  3AWE A;  1BZH A;  3AWG A;  3ZM0 A; 
#chains in the Genus database with same CATH topology
 2NT2 A;  3D44 A;  1BZC A;  2F6F A;  3MOW A;  3V0H A;  4GE5 A;  4GFV A;  1KAV A;  1NL9 A;  2NV5 A;  4WOH A;  2BV5 A;  4ZRT A;  4NYH A;  4OHH A;  1GWZ A;  2QBS A;  2B4S A;  4QAH A;  4H1O A;  2MBC A;  2VOR A;  3EZZ A;  4D3R A;  2I6J A;  5BZZ A;  1M3G A;  4GRY A;  1GQQ A;  1SUG A;  1ZC0 A;  4J51 A;  2CJZ A;  5KA9 A;  1P15 A;  1Q6S A;  3N0A A;  3RO1 A;  3D1O A;  2VEY A;  2GP0 A;  3PYZ A;  1G1F A;  3S3F A;  2JJD A;  4BPC A;  4I8N A;  4JNB A;  4AZ1 A;  3F9B A;  4YR8 B;  4PVG A;  1MKP A;  2F6V A;  2GCA A;  2I4G A;  2QDM A;  3ZM2 A;  3D9C A;  1Q6P A;  3U96 A;  1FQ1 A;  4PYH A;  1EEN A;  4ZIY A;  1Q1M A;  1E0D A;  4HV4 A;  4Z6B A;  4BJO A;  4Y2E A;  1PTT A;  2ZN7 A;  5BZX A;  1Q6N A;  2A3K A;  2QDP A;  2GC6 A;  3ZMP A;  2J17 A;  5K9W A;  1KAK A;  5K9V A;  1WAX A;  2JFH A;  2I42 A;  3BLU A;  4TVV A;  3BRH A;  5EHP A;  2VTE A;  4GRZ A;  2OOQ A;  2CMC A;  2B07 A;  3O4U A;  1RPM A;  1T49 A;  1XRI A;  2VOS A;  2VEV A;  2RF6 A;  1PYN A;  4R30 A;  2I4H A;  2GCB A;  5AWX A;  1OES A;  2CMB A;  1E8C A;  2HNP A;  5BX1 A;  4OHE A;  2QBP A;  1YTS A;  2CM7 A;  2CNE A;  2H4V A;  1U26 A;  4NWF A;  2Y68 A;  1GQY A;  1EEO A;  2UUP A;  2OZ5 A;  1G4W R;  3M4U A;  3SR9 A;  1J4X A;  4CVK A;  1ECV A;  1ZZW A;  2FJM A;  3CWE A;  1C86 A;  2QEP A;  2QDC A;  1YWF A;  1Q6M A;  4KI9 A;  3OMH A;  2E0T A;  1I57 A;  3V0G A;  2F6W A;  1I9S A;  3LJ8 A;  3ZM5 A;  4OHL A;  2JFG A;  2HC1 A;  1C87 A;  1JF7 A;  5K22 A;  1I9T A;  1L8G A;  1A5Y A;  1NZ7 A;  1PA9 A;  3QCE A;  2Y66 A;  4BUB A;  5KA2 A;  2BGE A;  3GXH A;  4HJQ A;  2I4E A;  1P31 A;  2UUO A;  4S0G A;  4QBE A;  2B4O A;  2CNI A;  2H03 A;  4D3Q A;  1T4J A;  1C84 A;  1YTW A;  2HB1 A;  3F41 A;  2J16 A;  2CNF A;  2DXP A;  5J8R A;  2GJT A;  3QCB A;  1GFY A;  2G59 A;  2PI7 A;  5I6V A;  4QF5 A;  3QCF A;  3V0J A;  3MOZ A;  1U24 A;  2BZL A;  2YDU A;  2PBN A;  2X5O A;  5KAA A;  3I80 A;  2I6P A;  1YGR A;  1C83 A;  3RZ2 A;  1QZ0 A;  4ZI4 A;  3D1H A;  4ZN5 A;  3LK7 A;  2WJP A;  4Y14 A;  5KA3 A;  3EMU A;  2B4U A;  3EB1 A;  1OEV A;  2CM8 A;  2QBQ A;  4HRF A;  2HXP A;  2FJN A;  2C46 A;  1W78 A;  3O4S A;  5KA4 A;  3S3H A;  2BIJ A;  4RHG A;  5LXQ B;  4QDI A;  1PTV A;  1YGU A;  2PA5 A;  1LAR A;  4ICZ A;  4RI4 A;  1JLN A;  4WTY A;  2VEU A;  4JMK A;  5KA8 A;  1WRM A;  1P3D A;  1U25 A;  2B4P A;  3SME A;  5IBM A;  1Q6T A;  1NO6 A;  3PS5 A;  1JBV A;  3QCG A;  2F00 A;  3NME A;  3ZV2 A;  3A5J A;  1L8K A;  2H4K A;  2I3U A;  1LYV A;  1YN9 A;  2J16 B;  4OHD A;  1G7F A;  3AWF A;  2CFV A;  4RI5 A;  4JBC A;  5MMZ B;  4QUN A;  3QCC A;  3V0F A;  3ZM6 A;  2I6I A;  2QCJ A;  1G1G A;  4YAA A;  2HY3 A;  1R6H A;  4H34 A;  4RDD A;  1PTU A;  3A5K A;  2NTA A;  2Y67 A;  2P4D A;  3S4E A;  1NNY A;  2Q05 A;  3RGQ A;  2GC5 A;  1JBW A;  3F9A A;  2F70 A;  3OLR A;  2Y2F A;  4B04 A;  2PT0 A;  2CNG A;  3QCL A;  5KA0 A;  4IKC A;  1NWE A;  1ONZ A;  3D1Q A;  3BLT A;  5K23 A;  2HVL A;  3ZMQ A;  3MVN A;  5K24 A;  1Q6J A;  2PQ5 A;  3V0I A;  1PH0 A;  3QCK A;  2VTD A;  4JMJ A;  3I7Z A;  4GWF A;  4QUM A;  3ZM3 A;  2I1Y A;  3B7O A;  2ESB A;  2OUD A;  3QCH A;  5A5F A;  4KYQ A;  1OHC A;  1PA1 A;  2VEX A;  4HJP A;  1YTN A;  3S3K A;  2NLK A;  5KAC A;  1PXH A;  1OHE A;  4NWG A;  4C12 A;  3EAX A;  1W7K A;  1T48 A;  3O3L A;  1WCH A;  3S3E A;  3RGO A;  2F71 A;  1OHD A;  4DGX A;  4CVL A;  2SHP A;  2UAG A;  2HC2 A;  2G6Z A;  1AAX A;  2WGP A;  2AM2 A;  1FGS A;  3F99 A;  4GE2 A;  1V3A A;  1RXD A;  2PSZ A;  1FPR A;  2VEW A;  3HN7 A;  3ZM1 A;  2Q47 A;  2XJA A;  1XBO A;  2NZ6 A;  3H2X A;  3QCD A;  4WU3 A;  1D5R A;  2H4G A;  1ZCK A;  2CNH A;  3QCZ A;  5IBS A;  5KAD A;  4RH9 A;  2AHS A;  3O4T A;  2H04 A;  1C85 A;  5M43 A;  3GXG A;  1G4U S;  1YZ4 A;  1NWL A;  4UAG A;  4NX8 A;  2M3V A;  2FH7 A;  1LQF A;  2OC3 A;  2F6T A;  2I75 A;  4DGP A;  2I5X A;  4ERC A;  4GE6 A;  5HDE A;  1G7G A;  2IMG A;  1C88 A;  1G1H A;  1EEH A;  4WU2 A;  1ZCL A;  1YPT A;  4R0S A;  4R0T A;  1QXK A;  3EU0 A;  5GTJ A;  2CMA A;  2HNQ A;  3O5X A;  3QCN A;  2QBR A;  3QKP A;  5KAB A;  2HCM A;  1GG4 A;  2B3O A;  4GFU A;  3F81 A;  1XM2 A;  1YFO A;  1O5Z A;  2F6Z A;  2QCT A;  1X24 A;  1OEM X;  3MMJ A;  2XPC A;  3V0D A;  4BUC A;  4RKK A;  1XXV A;  3QCM A;  3QCJ A;  2I3R A;  3D42 A;  3V0E A;  2CM3 A;  2F46 A;  5BUG A;  3NRS A;  2Y96 A;  2AM1 A;  2WTZ A;  3QKQ A;  1J6U A;  2R0B A;  2JFF A;  3ZL8 A;  4RH5 A;  5KA1 A;  4NND A;  1FPZ A;  2A8B A;  3CM3 A;  2H02 A;  4CVM A;  3UAG A;  1OEU A;  1BZJ A;  2I6M A;  2BGD A;  5KA7 A;  2NT7 A;  3BM8 A;  4GS0 A;  3I36 A;  3S4O A;  1OEO X;  1XXP A;  2B49 A;  2AZR A;  1UAG A;  2P6X A;  4MBB A;  3QCI A;  2F6Y A;  4OHI A;  1OET A;  4D3P A;  2C7S A;  1VHR A;  4QAP A;  5EHR A;  2CM2 A;  4KYR A;  1PTY A;  4QBW A;  2ZMM A;  1ONY A;  2GWO A;  3N2A A;  2Y1O A;  5A5E A;  5K25 A;  2I6O A;  3AWE A;  1BZH A;  4C13 A;  3AWG A;  3ZM0 A; 
#chains in the Genus database with same CATH homology
 2NT2 A;  3D44 A;  1BZC A;  2F6F A;  3MOW A;  3V0H A;  4GE5 A;  4GFV A;  1KAV A;  1NL9 A;  2NV5 A;  4WOH A;  2BV5 A;  4ZRT A;  4NYH A;  4OHH A;  1GWZ A;  2QBS A;  2B4S A;  4QAH A;  4H1O A;  2MBC A;  3EZZ A;  4D3R A;  2I6J A;  5BZZ A;  1M3G A;  4GRY A;  1SUG A;  1ZC0 A;  4J51 A;  2CJZ A;  5KA9 A;  1P15 A;  1Q6S A;  3N0A A;  3RO1 A;  3D1O A;  2VEY A;  2GP0 A;  1G1F A;  3S3F A;  2JJD A;  4BPC A;  4I8N A;  4JNB A;  4AZ1 A;  3F9B A;  4YR8 B;  4PVG A;  1MKP A;  2F6V A;  2I4G A;  2QDM A;  3ZM2 A;  3D9C A;  1Q6P A;  3U96 A;  1FQ1 A;  4PYH A;  1EEN A;  1Q1M A;  4Z6B A;  4BJO A;  4Y2E A;  1PTT A;  2ZN7 A;  5BZX A;  1Q6N A;  2A3K A;  2QDP A;  3ZMP A;  2J17 A;  5K9W A;  1KAK A;  5K9V A;  1WAX A;  2I42 A;  3BLU A;  4TVV A;  3BRH A;  5EHP A;  4GRZ A;  2OOQ A;  2CMC A;  2B07 A;  3O4U A;  1RPM A;  1T49 A;  1XRI A;  2VEV A;  2RF6 A;  1PYN A;  4R30 A;  2I4H A;  5AWX A;  1OES A;  2CMB A;  2HNP A;  5BX1 A;  4OHE A;  2QBP A;  1YTS A;  2CM7 A;  2CNE A;  2H4V A;  1U26 A;  4NWF A;  1EEO A;  2OZ5 A;  1G4W R;  3M4U A;  3SR9 A;  1J4X A;  1ECV A;  1ZZW A;  2FJM A;  3CWE A;  1C86 A;  2QEP A;  2QDC A;  1YWF A;  1Q6M A;  4KI9 A;  3OMH A;  2E0T A;  1I57 A;  3V0G A;  2F6W A;  1I9S A;  3LJ8 A;  4OHL A;  2HC1 A;  1C87 A;  1JF7 A;  5K22 A;  1I9T A;  1L8G A;  1A5Y A;  1NZ7 A;  1PA9 A;  3QCE A;  5KA2 A;  2BGE A;  3GXH A;  4HJQ A;  2I4E A;  4S0G A;  4QBE A;  2B4O A;  2CNI A;  2H03 A;  4D3Q A;  1T4J A;  1C84 A;  1YTW A;  2HB1 A;  3F41 A;  2J16 A;  2CNF A;  2DXP A;  5J8R A;  2GJT A;  3QCB A;  1GFY A;  2G59 A;  2PI7 A;  5I6V A;  3QCF A;  3V0J A;  3MOZ A;  1U24 A;  2BZL A;  2YDU A;  2PBN A;  5KAA A;  3I80 A;  2I6P A;  1YGR A;  1C83 A;  3RZ2 A;  1QZ0 A;  4ZI4 A;  3D1H A;  4ZN5 A;  4Y14 A;  5KA3 A;  3EMU A;  2B4U A;  3EB1 A;  1OEV A;  2CM8 A;  2QBQ A;  4HRF A;  2HXP A;  2FJN A;  2C46 A;  3O4S A;  5KA4 A;  3S3H A;  2BIJ A;  4RHG A;  5LXQ B;  1PTV A;  1YGU A;  2PA5 A;  1LAR A;  4ICZ A;  4RI4 A;  1JLN A;  4WTY A;  2VEU A;  4JMK A;  5KA8 A;  1WRM A;  3SME A;  1U25 A;  2B4P A;  5IBM A;  1Q6T A;  1NO6 A;  3PS5 A;  3QCG A;  3NME A;  3ZV2 A;  3A5J A;  1L8K A;  2H4K A;  2I3U A;  1LYV A;  1YN9 A;  2J16 B;  4OHD A;  1G7F A;  3AWF A;  2CFV A;  4RI5 A;  4JBC A;  5MMZ B;  4QUN A;  3QCC A;  3V0F A;  2I6I A;  2QCJ A;  1G1G A;  4YAA A;  2HY3 A;  1R6H A;  4H34 A;  4RDD A;  1PTU A;  3A5K A;  2NTA A;  3S4E A;  2P4D A;  1NNY A;  2Q05 A;  3RGQ A;  3F9A A;  2F70 A;  3OLR A;  2Y2F A;  4B04 A;  2PT0 A;  2CNG A;  3QCL A;  5KA0 A;  4IKC A;  1NWE A;  1ONZ A;  3D1Q A;  3BLT A;  5K23 A;  2HVL A;  3ZMQ A;  5K24 A;  1Q6J A;  2PQ5 A;  3V0I A;  1PH0 A;  3QCK A;  4JMJ A;  3I7Z A;  4GWF A;  4QUM A;  3ZM3 A;  2I1Y A;  3B7O A;  2ESB A;  2OUD A;  3QCH A;  4KYQ A;  1OHC A;  1PA1 A;  2VEX A;  4HJP A;  1YTN A;  3S3K A;  2NLK A;  5KAC A;  1PXH A;  1OHE A;  4NWG A;  3EAX A;  1T48 A;  3O3L A;  1WCH A;  3S3E A;  3RGO A;  2F71 A;  1OHD A;  4DGX A;  2SHP A;  2HC2 A;  2G6Z A;  1AAX A;  2WGP A;  3F99 A;  4GE2 A;  1V3A A;  1RXD A;  2PSZ A;  1FPR A;  2VEW A;  3ZM1 A;  2Q47 A;  1XBO A;  3QCD A;  2NZ6 A;  3H2X A;  4WU3 A;  1D5R A;  2H4G A;  1ZCK A;  2CNH A;  5IBS A;  5KAD A;  4RH9 A;  2AHS A;  3O4T A;  2H04 A;  1C85 A;  5M43 A;  3GXG A;  1G4U S;  1YZ4 A;  1NWL A;  4NX8 A;  2M3V A;  2FH7 A;  1LQF A;  2OC3 A;  2F6T A;  2I75 A;  4DGP A;  2I5X A;  4ERC A;  4GE6 A;  5HDE A;  1G7G A;  2IMG A;  1C88 A;  1G1H A;  4WU2 A;  1ZCL A;  1YPT A;  4R0S A;  4R0T A;  1QXK A;  3EU0 A;  5GTJ A;  2CMA A;  2HNQ A;  3O5X A;  3QCN A;  2QBR A;  3QKP A;  5KAB A;  2HCM A;  2B3O A;  4GFU A;  3F81 A;  1XM2 A;  1YFO A;  2F6Z A;  2QCT A;  1X24 A;  1OEM X;  3MMJ A;  3V0D A;  4RKK A;  1XXV A;  3QCM A;  3QCJ A;  2I3R A;  3D42 A;  3V0E A;  2CM3 A;  2F46 A;  5BUG A;  2Y96 A;  3QKQ A;  2R0B A;  4RH5 A;  5KA1 A;  4NND A;  1FPZ A;  2A8B A;  3CM3 A;  2H02 A;  1OEU A;  1BZJ A;  2I6M A;  2BGD A;  5KA7 A;  2NT7 A;  3BM8 A;  4GS0 A;  3I36 A;  3S4O A;  1OEO X;  1XXP A;  2B49 A;  2AZR A;  2P6X A;  4MBB A;  3QCI A;  2F6Y A;  4OHI A;  1OET A;  4D3P A;  2C7S A;  1VHR A;  4QAP A;  5EHR A;  2CM2 A;  4KYR A;  1PTY A;  4QBW A;  2ZMM A;  1ONY A;  2GWO A;  5K25 A;  2I6O A;  3AWE A;  1BZH A;  3AWG A;  3ZM0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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