5HE1G

Human grk2 in complex with gbetagamma subunits and ccg224062
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
62
structure length
62
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 17
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he1G00
1B9YB 5HE1G 3KRWG 1B9XB 5HE0G 3SN6G 5KDOG 3KRXG 2BCJG 3AH8G 3PVWG 5HE2G 1GG2G 1GOTG 4KFMG 1XHMB 3CIKG 2PBIA 4PNKG 2TRCG 1OMWG 1GP2G 3V5WG 5TDHG 5HE3G 1TBGE 3PSCG 4MK0G 1A0RG 3PVUG
chains in the Genus database with same CATH superfamily
1B9YB 5HE1G 3KRWG 1B9XB 5HE0G 3SN6G 5KDOG 3KRXG 2BCJG 3AH8G 3PVWG 5HE2G 1GG2G 1GOTG 4KFMG 1XHMB 1IOJA 3CIKG 2PBIA 4PNKG 2TRCG 1OMWG 1GP2G 3V5WG 5TDHG 5HE3G 1TBGE 3PSCG 1HFES 4MK0G 1A0RG 3PVUG
chains in the Genus database with same CATH topology
1B9YB 5HE1G 3KRWG 1B9XB 5HE0G 3SN6G 5KDOG 3KRXG 2BCJG 3AH8G 3PVWG 5HE2G 1GG2G 1GOTG 4KFMG 1XHMB 3CIKG 2PBIA 4PNKG 2TRCG 1OMWG 1GP2G 3V5WG 5TDHG 5HE3G 1TBGE 3PSCG 4MK0G 1A0RG 3PVUG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B9Y B;  5HE1 G;  3KRW G;  1B9X B;  5HE0 G;  3SN6 G;  5KDO G;  3KRX G;  2BCJ G;  3AH8 G;  3PVW G;  5HE2 G;  1GG2 G;  1GOT G;  4KFM G;  1XHM B;  3CIK G;  2PBI A;  4PNK G;  2TRC G;  1OMW G;  1GP2 G;  3V5W G;  5TDH G;  5HE3 G;  1TBG E;  3PSC G;  4MK0 G;  1A0R G;  3PVU G; 
#chains in the Genus database with same CATH topology
 1B9Y B;  5HE1 G;  3KRW G;  1B9X B;  5HE0 G;  3SN6 G;  5KDO G;  3KRX G;  2BCJ G;  3AH8 G;  3PVW G;  5HE2 G;  1GG2 G;  1GOT G;  4KFM G;  1XHM B;  1IOJ A;  3CIK G;  2PBI A;  4PNK G;  2TRC G;  1OMW G;  1GP2 G;  3V5W G;  5TDH G;  5HE3 G;  1TBG E;  3PSC G;  1HFE S;  4MK0 G;  1A0R G;  3PVU G; 
#chains in the Genus database with same CATH homology
 1B9Y B;  5HE1 G;  3KRW G;  1B9X B;  5HE0 G;  3SN6 G;  5KDO G;  3KRX G;  2BCJ G;  3AH8 G;  3PVW G;  5HE2 G;  1GG2 G;  1GOT G;  4KFM G;  1XHM B;  3CIK G;  2PBI A;  4PNK G;  2TRC G;  1OMW G;  1GP2 G;  3V5W G;  5TDH G;  5HE3 G;  1TBG E;  3PSC G;  4MK0 G;  1A0R G;  3PVU G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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