5HUIA

6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl)
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human dihydrofolate reductase ternary complex with a series of 6-substituted pyrido[3,2]pyrimidine-6-(4'-trifluoromethoxypheny)-2,4-diamines
rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
total genus 53
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2016-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5huiA00
5U26A 2HM9A 3KJRA 1RA2A 2W3MA 3IRMA 3GYFA 1DG5A 3ROAA 1RX1A 4ECKA 2L28A 4OSGA 2C2SA 3DL5A 4HA9A 1CD2A 1LY4A 4KEBA 3JWFA 1RX7A 1JOMA 3JWKA 3EEMA 4QJZD 3TQAA 3DRCA 1RX9A 3D84X 1IA3A 3F0BX 5HUIA 2W9TA 3FYWX 1D1GA 3SA1A 2W3WA 1IA1A 1DR7A 1DR2A 1RA8A 1RF7A 1VDRA 3TD8A 1RA1A 2HXVA 3NZ6X 3M09A 4H98A 3SA2A 2INQA 1DR1A 4P3QA 1BOZA 4XECX 1DYJA 4IXGX 5DXVA 4PDJA 4X5GA 3F0UX 1PD9A 5HF0X 3SAIA 5HVBA 3CSEA 3QG2A 3R33A 3CD2A 3K74A 4TU5X 1U70A 4KY4A 8DFRA 1SEJA 4P3RA 3KJSA 3F0QX 3NXYA 1AOEA 5HPBA 3QLXA 4M6KA 2QK8A 2FZIA 4LAEX 4M7UA 1IA2A 4XE6X 3NZBX 3SR5X 3M08A 3QGTA 3RO9A 3DAUA 3EELA 3L3RA 1DG8A 1DRFA 1HFPA 3FY9X 4ELEA 1DLRA 1DHFA 1S3WA 1DR4A 2FZJA 3LG4A 3SRRX 5HF2X 1DG7A 4X5IA 3UM6A 5HQZA 4M6LA 3QLSA 2W9GA 2ANOA 2G6VA 3N0HA 2H2QA 3E0BA 1HFQA 1IA4A 3NZCX 3DG8A 5HQYA 2HQPA 1DDSA 3QLYA 1RG7A 1KMSA 4DP3A 4KJLA 4Q0EA 4HOGA 2P4GA 4PSTA 5HVEA 1RX3A 4G3MA 1DYIA 3F8ZA 3KGYA 3EEJA 3IA5A 4DPHA 5DFRA 2ZZAA 4M6JA 1J3KA 1S3UA 4H95A 4Q0DA 1YHOA 2O7PA 4XRBA 3QFXA 3FREX 4KJJA 3CLBA 1DDRA 3I3RA 4PTJA 3SRQX 1U71A 4I1NA 3IRNA 4EJ1A 3RG9A 1DR3A 3GHVA 4XT6A 3EEKA 2BLAA 3F91A 3FS6A 2ANQA 4PTHA 1S3VA 2BLCA 2LF1A 4QLEA 1OHKA 1DREA 5E8QA 1U72A 1JOLA 2GD9A 1DHIA 4NX6A 3IROA 4M2XA 3NRRA 3FY8X 3K2HA 3NXVA 4KY8A 1DIUA 5HT4A 1BZFA 3S7AA 1DRAA 4ELGA 3TQBA 3DL6A 1AO8A 3FL9A 3SRWX 4XT5A 1RX8A 4I13A 1E26A 3INVA 3QYOA 2DRCA 2W3BA 3FYVX 4FGGA 3I8AX 3HJ3A 5HSRA 1RX2A 3UM5A 1M78A 3VCOA 3NXRA 1S3YA 3JWMA 3NZDA 1RX4A 1M79A 4HOFA 1TDRA 3FQFA 3JSUA 3FRBX 1LY3A 4KM2A 1VJ3A 3OCHA 7DFRA 4CD2A 3FQOA 3K47A 1DAJA 4H97A 1DHJA 2OBCA 3QL3A 4QJCA 3SQYX 3GHWA 5JA3A 4EIZA 3EX8A 3JTWA 3FQZA 5ECXA 3NZ9X 4ELBA 3D80A 3EIGA 4G8ZX 3CL9A 3FRAX 4X5FA 4XT4A 1RX6A 4FHBA 1RA3A 3NXXA 4KLXA 4X5HA 3NU0A 1DF7A 4PSSA 3QLRA 2W9HA 5HSUA 5JG0X 3QLWA 1J3IA 4QHVA 3NXOA 4IXED 1DRBA 2W9SA 3DATA 3KFYA 6DFRA 3S3VA 4FGHA 4QLGA 1DR6A 3F8YA 5EAJA 4KM0A 4DFRA 4QLFA 3ZPGA 3QYLA 1M7AA 2B3ZA 3F0XX 1PDBA 4KYAA 3FL8A 4LAHX 4OR7A 1DISA 3S9UA 3FQ0A 2BL9A 2W3VA 3JW3A 4IXFX 3ZPCA 4M7VA 3JW5A 1RA9A 3K45A 4HA7A 4EILA 3GHCA 4GH8A 4KFJA 4DDRA 4XT8A 5ECCA 5FDAA 1CZ3A 3GI2A 4H96A 4Q6AA 4QI9A 3FRFX 3JWCA 2JYBA 1DYHA 3DFRA 3F0VX 5U27A 4XT7A 1JUVA 1J3JA 1RB2A 4LEKX 4KAKA 1RX5A 4X5JA 4HOEA 2C2TA 3FRDX 3SH2A 2XW7A 3SRUX 2DHFA 4KJKA 3TQ9A 2D0KA 3SGYA 1MVSA 2OIPA 3KY8A 3QL0A 1RB3A 1RH3A 2ITHA 3IX9A 1LUDA 1OHJA 4P66A 2CD2A 4KBNA 5HI6A 1HFRA 1DLSA 4ELHA 4KL9A 3F0SX 4ELFA 1KLKA 4P68A 2D5NA 2BLBA 3Q1HA 3OAFA 3FQCA 1AI9A 3NZAX 3NTZA 4G95A 1RC4A 3TQ8A 1RE7A 3IA4A 4RGCA 1DYRA 2AZNA 3NXTA 1ZDRA 1PD8A 4EIGA 4DPDA 1DRHA 2CIGA 4PSYA 2KGKA 5CC9A 5HT5A 3DGAA 4KD7A 3JVXA 3HBBA 1QZFA 5CCCA 2W3AA 1RD7A 4Q67A 3QLZA 3SRSX 4LAGX 3FQVA 1KMVA 1DR5A 4KNEA 4NX7A 3UM8A 1MVTA 2FZHA
chains in the Genus database with same CATH superfamily
5U26A 2HM9A 3KJRA 1RA2A 2W3MA 3IRMA 3GYFA 1DG5A 3ROAA 1RX1A 4ECKA 2L28A 4OSGA 2C2SA 3DL5A 4HA9A 1CD2A 1LY4A 4KEBA 3JWFA 1RX7A 1JOMA 3JWKA 3EEMA 4QJZD 3TQAA 3DRCA 1RX9A 3D84X 1IA3A 3F0BX 5HUIA 2W9TA 3FYWX 1D1GA 3SA1A 2W3WA 1IA1A 1DR7A 1DR2A 1RA8A 1RF7A 1VDRA 3TD8A 1RA1A 2HXVA 3NZ6X 3M09A 4H98A 3SA2A 2INQA 1DR1A 4P3QA 1BOZA 4XECX 1DYJA 4IXGX 5DXVA 4PDJA 4X5GA 3F0UX 1PD9A 5HF0X 3SAIA 5HVBA 3CSEA 3QG2A 3R33A 3CD2A 3K74A 4TU5X 1U70A 4KY4A 8DFRA 1SEJA 4P3RA 3KJSA 3F0QX 3NXYA 1AOEA 5HPBA 3QLXA 4M6KA 2QK8A 2FZIA 4LAEX 4M7UA 1IA2A 4XE6X 3NZBX 3SR5X 3M08A 3QGTA 3RO9A 3DAUA 3EELA 3L3RA 1DG8A 1DRFA 1HFPA 3FY9X 4ELEA 1DLRA 1DHFA 1S3WA 1DR4A 2FZJA 3LG4A 3SRRX 5HF2X 1DG7A 4X5IA 3UM6A 5HQZA 4M6LA 3QLSA 2W9GA 2ANOA 2G6VA 3N0HA 2H2QA 3E0BA 1HFQA 1IA4A 3NZCX 3DG8A 5HQYA 2HQPA 1DDSA 3QLYA 1RG7A 1KMSA 4DP3A 4KJLA 4Q0EA 4HOGA 2P4GA 4PSTA 5HVEA 1RX3A 4G3MA 1DYIA 3F8ZA 3KGYA 3EEJA 3IA5A 4DPHA 5DFRA 2ZZAA 4M6JA 1J3KA 1S3UA 4H95A 4Q0DA 1YHOA 2O7PA 4XRBA 3QFXA 3FREX 4KJJA 3CLBA 1DDRA 3I3RA 4PTJA 3SRQX 1U71A 4I1NA 3IRNA 4EJ1A 3RG9A 1DR3A 3GHVA 4XT6A 3EEKA 2BLAA 3F91A 3FS6A 2ANQA 4PTHA 1S3VA 2BLCA 2LF1A 4QLEA 1OHKA 1DREA 5E8QA 1U72A 1JOLA 2GD9A 1DHIA 4NX6A 3IROA 4M2XA 3NRRA 3FY8X 3K2HA 3NXVA 4KY8A 1DIUA 5HT4A 1BZFA 3S7AA 1DRAA 4ELGA 3TQBA 3DL6A 1AO8A 3FL9A 3SRWX 4XT5A 1RX8A 4I13A 1E26A 3INVA 3QYOA 2DRCA 2W3BA 3FYVX 4FGGA 3I8AX 3HJ3A 5HSRA 1RX2A 3UM5A 1M78A 3VCOA 3NXRA 1S3YA 3JWMA 3NZDA 1RX4A 1M79A 4HOFA 1TDRA 3FQFA 3JSUA 3FRBX 1LY3A 4KM2A 1VJ3A 3OCHA 7DFRA 4CD2A 3FQOA 3K47A 1DAJA 4H97A 1DHJA 2OBCA 3QL3A 4QJCA 3SQYX 3GHWA 5JA3A 4EIZA 3EX8A 3JTWA 3FQZA 5ECXA 3NZ9X 4ELBA 3D80A 3EIGA 4G8ZX 3CL9A 3FRAX 4X5FA 4XT4A 1RX6A 4FHBA 1RA3A 3NXXA 4KLXA 4X5HA 3NU0A 1DF7A 4PSSA 3QLRA 2W9HA 5HSUA 5JG0X 3QLWA 1J3IA 4QHVA 3NXOA 4IXED 1DRBA 2W9SA 3DATA 3KFYA 6DFRA 3S3VA 4FGHA 4QLGA 1DR6A 3F8YA 5EAJA 4KM0A 4DFRA 4QLFA 3ZPGA 3QYLA 1M7AA 2B3ZA 3F0XX 1PDBA 4KYAA 3FL8A 4LAHX 4OR7A 1DISA 3S9UA 3FQ0A 2BL9A 2W3VA 3JW3A 4IXFX 3ZPCA 4M7VA 3JW5A 1RA9A 3K45A 4HA7A 4EILA 3GHCA 4GH8A 4KFJA 4DDRA 4XT8A 5ECCA 5FDAA 1CZ3A 3GI2A 4H96A 4Q6AA 4QI9A 3FRFX 3JWCA 2JYBA 1DYHA 3DFRA 3F0VX 5U27A 4XT7A 1JUVA 1J3JA 1RB2A 4LEKX 4KAKA 1RX5A 4X5JA 4HOEA 2C2TA 3FRDX 3SH2A 2XW7A 3SRUX 2DHFA 4KJKA 3TQ9A 2D0KA 3SGYA 1MVSA 2OIPA 3KY8A 3QL0A 1RB3A 1RH3A 2ITHA 3IX9A 1LUDA 1OHJA 4P66A 2CD2A 4KBNA 5HI6A 1HFRA 1DLSA 4ELHA 4KL9A 3F0SX 4ELFA 1KLKA 4P68A 2D5NA 2BLBA 3Q1HA 3OAFA 3FQCA 1AI9A 3NZAX 3NTZA 4G95A 1RC4A 3TQ8A 1RE7A 3IA4A 4RGCA 1DYRA 2AZNA 3NXTA 1ZDRA 1PD8A 4EIGA 4DPDA 1DRHA 2CIGA 4PSYA 2KGKA 5CC9A 5HT5A 3DGAA 4KD7A 3JVXA 3HBBA 1QZFA 5CCCA 2W3AA 1RD7A 4Q67A 3QLZA 3SRSX 4LAGX 3FQVA 1KMVA 1DR5A 4KNEA 4NX7A 3UM8A 1MVTA 2FZHA
chains in the Genus database with same CATH topology
5U26A 2HM9A 3KJRA 1RA2A 2W3MA 3IRMA 3GYFA 1DG5A 3ROAA 1RX1A 4ECKA 2L28A 4OSGA 2C2SA 3DL5A 4HA9A 1CD2A 1LY4A 4KEBA 3JWFA 1RX7A 1JOMA 3JWKA 3EEMA 4QJZD 3TQAA 3DRCA 1RX9A 3D84X 1IA3A 3F0BX 5HUIA 2W9TA 3FYWX 1D1GA 3SA1A 2W3WA 1IA1A 1DR7A 1DR2A 1RA8A 1RF7A 1VDRA 3TD8A 1RA1A 2HXVA 3NZ6X 3M09A 4H98A 3SA2A 2INQA 1DR1A 4P3QA 1BOZA 4XECX 1DYJA 4IXGX 5DXVA 4PDJA 4X5GA 3F0UX 1PD9A 5HF0X 3SAIA 5HVBA 3CSEA 3QG2A 3R33A 3CD2A 3K74A 4TU5X 1U70A 4KY4A 8DFRA 1SEJA 4P3RA 3KJSA 3F0QX 3NXYA 1AOEA 5HPBA 3QLXA 4M6KA 2QK8A 2FZIA 4LAEX 4M7UA 1IA2A 4XE6X 3NZBX 3SR5X 3M08A 3QGTA 3RO9A 3DAUA 3EELA 3L3RA 1DG8A 1DRFA 1HFPA 3FY9X 4ELEA 1DLRA 1DHFA 1S3WA 1DR4A 2FZJA 3LG4A 3SRRX 5HF2X 1DG7A 4X5IA 3UM6A 5HQZA 4M6LA 3QLSA 2W9GA 2ANOA 2G6VA 3N0HA 2H2QA 3E0BA 1HFQA 1IA4A 3NZCX 3DG8A 5HQYA 2HQPA 1DDSA 3QLYA 1RG7A 1KMSA 4DP3A 4KJLA 4Q0EA 4HOGA 2P4GA 4PSTA 5HVEA 1RX3A 4G3MA 1DYIA 3F8ZA 3KGYA 3EEJA 3IA5A 4DPHA 5DFRA 2ZZAA 4M6JA 1J3KA 1S3UA 4H95A 4Q0DA 1YHOA 2O7PA 4XRBA 3QFXA 3FREX 4KJJA 3CLBA 1DDRA 3I3RA 4PTJA 3SRQX 1U71A 4I1NA 3IRNA 4EJ1A 3RG9A 1DR3A 3GHVA 4XT6A 3EEKA 2BLAA 3F91A 3FS6A 2ANQA 4PTHA 1S3VA 2BLCA 2LF1A 4QLEA 1OHKA 1DREA 5E8QA 1U72A 1JOLA 2GD9A 1DHIA 4NX6A 3IROA 4M2XA 3NRRA 3FY8X 3K2HA 3NXVA 4KY8A 1DIUA 5HT4A 1BZFA 3S7AA 1DRAA 4ELGA 3TQBA 3DL6A 1AO8A 3FL9A 3SRWX 4XT5A 1RX8A 4I13A 1E26A 3INVA 3QYOA 2DRCA 2W3BA 3FYVX 4FGGA 3I8AX 3HJ3A 5HSRA 1RX2A 3UM5A 1M78A 3VCOA 3NXRA 1S3YA 3JWMA 3NZDA 1RX4A 1M79A 4HOFA 1TDRA 3FQFA 3JSUA 3FRBX 1LY3A 4KM2A 1VJ3A 3OCHA 7DFRA 4CD2A 3FQOA 3K47A 1DAJA 4H97A 1DHJA 2OBCA 3QL3A 4QJCA 3SQYX 3GHWA 5JA3A 4EIZA 3EX8A 3JTWA 3FQZA 5ECXA 3NZ9X 4ELBA 3D80A 3EIGA 4G8ZX 3CL9A 3FRAX 4X5FA 4XT4A 1RX6A 4FHBA 1RA3A 3NXXA 4KLXA 4X5HA 3NU0A 1DF7A 4PSSA 3QLRA 2W9HA 5HSUA 5JG0X 3QLWA 1J3IA 4QHVA 3NXOA 4IXED 1DRBA 2W9SA 3DATA 3KFYA 6DFRA 3S3VA 4FGHA 4QLGA 1DR6A 3F8YA 5EAJA 4KM0A 4DFRA 4QLFA 3ZPGA 3QYLA 1M7AA 2B3ZA 3F0XX 1PDBA 4KYAA 3FL8A 4LAHX 4OR7A 1DISA 3S9UA 3FQ0A 2BL9A 2W3VA 3JW3A 4IXFX 3ZPCA 4M7VA 3JW5A 1RA9A 3K45A 4HA7A 4EILA 3GHCA 4GH8A 4KFJA 4DDRA 4XT8A 5ECCA 5FDAA 1CZ3A 3GI2A 4H96A 4Q6AA 4QI9A 3FRFX 3JWCA 2JYBA 1DYHA 3DFRA 3F0VX 5U27A 4XT7A 1JUVA 1J3JA 1RB2A 4LEKX 4KAKA 1RX5A 4X5JA 4HOEA 2C2TA 3FRDX 3SH2A 2XW7A 3SRUX 2DHFA 4KJKA 3TQ9A 2D0KA 3SGYA 1MVSA 2OIPA 3KY8A 3QL0A 1RB3A 1RH3A 2ITHA 3IX9A 1LUDA 1OHJA 4P66A 2CD2A 4KBNA 5HI6A 1HFRA 1DLSA 4ELHA 4KL9A 3F0SX 4ELFA 1KLKA 4P68A 2D5NA 2BLBA 3Q1HA 3OAFA 3FQCA 1AI9A 3NZAX 3NTZA 4G95A 1RC4A 3TQ8A 1RE7A 3IA4A 4RGCA 1DYRA 2AZNA 3NXTA 1ZDRA 1PD8A 4EIGA 4DPDA 1DRHA 2CIGA 4PSYA 2KGKA 5CC9A 5HT5A 3DGAA 4KD7A 3JVXA 3HBBA 1QZFA 5CCCA 2W3AA 1RD7A 4Q67A 3QLZA 3SRSX 4LAGX 3FQVA 1KMVA 1DR5A 4KNEA 4NX7A 3UM8A 1MVTA 2FZHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5U26 A;  2HM9 A;  3KJR A;  1RA2 A;  2W3M A;  3IRM A;  3GYF A;  1DG5 A;  3ROA A;  1RX1 A;  4ECK A;  2L28 A;  4OSG A;  2C2S A;  3DL5 A;  4HA9 A;  1CD2 A;  1LY4 A;  4KEB A;  3JWF A;  1RX7 A;  1JOM A;  3JWK A;  3EEM A;  4QJZ D;  3TQA A;  3DRC A;  1RX9 A;  3D84 X;  1IA3 A;  3F0B X;  5HUI A;  2W9T A;  3FYW X;  1D1G A;  3SA1 A;  2W3W A;  1IA1 A;  1DR7 A;  1DR2 A;  1RA8 A;  1RF7 A;  1VDR A;  3TD8 A;  1RA1 A;  2HXV A;  3NZ6 X;  3M09 A;  4H98 A;  3SA2 A;  2INQ A;  1DR1 A;  4P3Q A;  1BOZ A;  4XEC X;  1DYJ A;  4IXG X;  5DXV A;  4PDJ A;  4X5G A;  3F0U X;  1PD9 A;  5HF0 X;  3SAI A;  5HVB A;  3CSE A;  3QG2 A;  3R33 A;  3CD2 A;  3K74 A;  4TU5 X;  1U70 A;  4KY4 A;  8DFR A;  1SEJ A;  4P3R A;  3KJS A;  3F0Q X;  3NXY A;  1AOE A;  5HPB A;  3QLX A;  4M6K A;  2QK8 A;  2FZI A;  4LAE X;  4M7U A;  1IA2 A;  4XE6 X;  3NZB X;  3SR5 X;  3M08 A;  3QGT A;  3RO9 A;  3DAU A;  3EEL A;  3L3R A;  1DG8 A;  1DRF A;  1HFP A;  3FY9 X;  4ELE A;  1DLR A;  1DHF A;  1S3W A;  1DR4 A;  2FZJ A;  3LG4 A;  3SRR X;  5HF2 X;  1DG7 A;  4X5I A;  3UM6 A;  5HQZ A;  4M6L A;  3QLS A;  2W9G A;  2ANO A;  2G6V A;  3N0H A;  2H2Q A;  3E0B A;  1HFQ A;  1IA4 A;  3NZC X;  3DG8 A;  5HQY A;  2HQP A;  1DDS A;  3QLY A;  1RG7 A;  1KMS A;  4DP3 A;  4KJL A;  4Q0E A;  4HOG A;  2P4G A;  4PST A;  5HVE A;  1RX3 A;  4G3M A;  1DYI A;  3F8Z A;  3KGY A;  3EEJ A;  3IA5 A;  4DPH A;  5DFR A;  2ZZA A;  4M6J A;  1J3K A;  1S3U A;  4H95 A;  4Q0D A;  1YHO A;  2O7P A;  4XRB A;  3QFX A;  3FRE X;  4KJJ A;  3CLB A;  1DDR A;  3I3R A;  4PTJ A;  3SRQ X;  1U71 A;  4I1N A;  3IRN A;  4EJ1 A;  3RG9 A;  1DR3 A;  3GHV A;  4XT6 A;  3EEK A;  2BLA A;  3F91 A;  3FS6 A;  2ANQ A;  4PTH A;  1S3V A;  2BLC A;  2LF1 A;  4QLE A;  1OHK A;  1DRE A;  5E8Q A;  1U72 A;  1JOL A;  2GD9 A;  1DHI A;  4NX6 A;  3IRO A;  4M2X A;  3NRR A;  3FY8 X;  3K2H A;  3NXV A;  4KY8 A;  1DIU A;  5HT4 A;  1BZF A;  3S7A A;  1DRA A;  4ELG A;  3TQB A;  3DL6 A;  1AO8 A;  3FL9 A;  3SRW X;  4XT5 A;  1RX8 A;  4I13 A;  1E26 A;  3INV A;  3QYO A;  2DRC A;  2W3B A;  3FYV X;  4FGG A;  3I8A X;  3HJ3 A;  5HSR A;  1RX2 A;  3UM5 A;  1M78 A;  3VCO A;  3NXR A;  1S3Y A;  3JWM A;  3NZD A;  1RX4 A;  1M79 A;  4HOF A;  1TDR A;  3FQF A;  3JSU A;  3FRB X;  1LY3 A;  4KM2 A;  1VJ3 A;  3OCH A;  7DFR A;  4CD2 A;  3FQO A;  3K47 A;  1DAJ A;  4H97 A;  1DHJ A;  2OBC A;  3QL3 A;  4QJC A;  3SQY X;  3GHW A;  5JA3 A;  4EIZ A;  3EX8 A;  3JTW A;  3FQZ A;  5ECX A;  3NZ9 X;  4ELB A;  3D80 A;  3EIG A;  4G8Z X;  3CL9 A;  3FRA X;  4X5F A;  4XT4 A;  1RX6 A;  4FHB A;  1RA3 A;  3NXX A;  4KLX A;  4X5H A;  3NU0 A;  1DF7 A;  4PSS A;  3QLR A;  2W9H A;  5HSU A;  5JG0 X;  3QLW A;  1J3I A;  4QHV A;  3NXO A;  4IXE D;  1DRB A;  2W9S A;  3DAT A;  3KFY A;  6DFR A;  3S3V A;  4FGH A;  4QLG A;  1DR6 A;  3F8Y A;  5EAJ A;  4KM0 A;  4DFR A;  4QLF A;  3ZPG A;  3QYL A;  1M7A A;  2B3Z A;  3F0X X;  1PDB A;  4KYA A;  3FL8 A;  4LAH X;  4OR7 A;  1DIS A;  3S9U A;  3FQ0 A;  2BL9 A;  2W3V A;  3JW3 A;  4IXF X;  3ZPC A;  4M7V A;  3JW5 A;  1RA9 A;  3K45 A;  4HA7 A;  4EIL A;  3GHC A;  4GH8 A;  4KFJ A;  4DDR A;  4XT8 A;  5ECC A;  5FDA A;  1CZ3 A;  3GI2 A;  4H96 A;  4Q6A A;  4QI9 A;  3FRF X;  3JWC A;  2JYB A;  1DYH A;  3DFR A;  3F0V X;  5U27 A;  4XT7 A;  1JUV A;  1J3J A;  1RB2 A;  4LEK X;  4KAK A;  1RX5 A;  4X5J A;  4HOE A;  2C2T A;  3FRD X;  3SH2 A;  2XW7 A;  3SRU X;  2DHF A;  4KJK A;  3TQ9 A;  2D0K A;  3SGY A;  1MVS A;  2OIP A;  3KY8 A;  3QL0 A;  1RB3 A;  1RH3 A;  2ITH A;  3IX9 A;  1LUD A;  1OHJ A;  4P66 A;  2CD2 A;  4KBN A;  5HI6 A;  1HFR A;  1DLS A;  4ELH A;  4KL9 A;  3F0S X;  4ELF A;  1KLK A;  4P68 A;  2D5N A;  2BLB A;  3Q1H A;  3OAF A;  3FQC A;  1AI9 A;  3NZA X;  3NTZ A;  4G95 A;  1RC4 A;  3TQ8 A;  1RE7 A;  3IA4 A;  4RGC A;  1DYR A;  2AZN A;  3NXT A;  1ZDR A;  1PD8 A;  4EIG A;  4DPD A;  1DRH A;  2CIG A;  4PSY A;  2KGK A;  5CC9 A;  5HT5 A;  3DGA A;  4KD7 A;  3JVX A;  3HBB A;  1QZF A;  5CCC A;  2W3A A;  1RD7 A;  4Q67 A;  3QLZ A;  3SRS X;  4LAG X;  3FQV A;  1KMV A;  1DR5 A;  4KNE A;  4NX7 A;  3UM8 A;  1MVT A;  2FZH A; 
#chains in the Genus database with same CATH topology
 5U26 A;  2HM9 A;  3KJR A;  1RA2 A;  2W3M A;  3IRM A;  3GYF A;  1DG5 A;  3ROA A;  1RX1 A;  4ECK A;  2L28 A;  4OSG A;  2C2S A;  3DL5 A;  4HA9 A;  1CD2 A;  1LY4 A;  4KEB A;  3JWF A;  1RX7 A;  1JOM A;  3JWK A;  3EEM A;  4QJZ D;  3TQA A;  3DRC A;  1RX9 A;  3D84 X;  1IA3 A;  3F0B X;  5HUI A;  2W9T A;  3FYW X;  1D1G A;  3SA1 A;  2W3W A;  1IA1 A;  1DR7 A;  1DR2 A;  1RA8 A;  1RF7 A;  1VDR A;  3TD8 A;  1RA1 A;  2HXV A;  3NZ6 X;  3M09 A;  4H98 A;  3SA2 A;  2INQ A;  1DR1 A;  4P3Q A;  1BOZ A;  4XEC X;  1DYJ A;  4IXG X;  5DXV A;  4PDJ A;  4X5G A;  3F0U X;  1PD9 A;  5HF0 X;  3SAI A;  5HVB A;  3CSE A;  3QG2 A;  3R33 A;  3CD2 A;  3K74 A;  4TU5 X;  1U70 A;  4KY4 A;  8DFR A;  1SEJ A;  4P3R A;  3KJS A;  3F0Q X;  3NXY A;  1AOE A;  5HPB A;  3QLX A;  4M6K A;  2QK8 A;  2FZI A;  4LAE X;  4M7U A;  1IA2 A;  4XE6 X;  3NZB X;  3SR5 X;  3M08 A;  3QGT A;  3RO9 A;  3DAU A;  3EEL A;  3L3R A;  1DG8 A;  1DRF A;  1HFP A;  3FY9 X;  4ELE A;  1DLR A;  1DHF A;  1S3W A;  1DR4 A;  2FZJ A;  3LG4 A;  3SRR X;  5HF2 X;  1DG7 A;  4X5I A;  3UM6 A;  5HQZ A;  4M6L A;  3QLS A;  2W9G A;  2ANO A;  2G6V A;  3N0H A;  2H2Q A;  3E0B A;  1HFQ A;  1IA4 A;  3NZC X;  3DG8 A;  5HQY A;  2HQP A;  1DDS A;  3QLY A;  1RG7 A;  1KMS A;  4DP3 A;  4KJL A;  4Q0E A;  4HOG A;  2P4G A;  4PST A;  5HVE A;  1RX3 A;  4G3M A;  1DYI A;  3F8Z A;  3KGY A;  3EEJ A;  3IA5 A;  4DPH A;  5DFR A;  2ZZA A;  4M6J A;  1J3K A;  1S3U A;  4H95 A;  4Q0D A;  1YHO A;  2O7P A;  4XRB A;  3QFX A;  3FRE X;  4KJJ A;  3CLB A;  1DDR A;  3I3R A;  4PTJ A;  3SRQ X;  1U71 A;  4I1N A;  3IRN A;  4EJ1 A;  3RG9 A;  1DR3 A;  3GHV A;  4XT6 A;  3EEK A;  2BLA A;  3F91 A;  3FS6 A;  2ANQ A;  4PTH A;  1S3V A;  2BLC A;  2LF1 A;  4QLE A;  1OHK A;  1DRE A;  5E8Q A;  1U72 A;  1JOL A;  2GD9 A;  1DHI A;  4NX6 A;  3IRO A;  4M2X A;  3NRR A;  3FY8 X;  3K2H A;  3NXV A;  4KY8 A;  1DIU A;  5HT4 A;  1BZF A;  3S7A A;  1DRA A;  4ELG A;  3TQB A;  3DL6 A;  1AO8 A;  3FL9 A;  3SRW X;  4XT5 A;  1RX8 A;  4I13 A;  1E26 A;  3INV A;  3QYO A;  2DRC A;  2W3B A;  3FYV X;  4FGG A;  3I8A X;  3HJ3 A;  5HSR A;  1RX2 A;  3UM5 A;  1M78 A;  3VCO A;  3NXR A;  1S3Y A;  3JWM A;  3NZD A;  1RX4 A;  1M79 A;  4HOF A;  1TDR A;  3FQF A;  3JSU A;  3FRB X;  1LY3 A;  4KM2 A;  1VJ3 A;  3OCH A;  7DFR A;  4CD2 A;  3FQO A;  3K47 A;  1DAJ A;  4H97 A;  1DHJ A;  2OBC A;  3QL3 A;  4QJC A;  3SQY X;  3GHW A;  5JA3 A;  4EIZ A;  3EX8 A;  3JTW A;  3FQZ A;  5ECX A;  3NZ9 X;  4ELB A;  3D80 A;  3EIG A;  4G8Z X;  3CL9 A;  3FRA X;  4X5F A;  4XT4 A;  1RX6 A;  4FHB A;  1RA3 A;  3NXX A;  4KLX A;  4X5H A;  3NU0 A;  1DF7 A;  4PSS A;  3QLR A;  2W9H A;  5HSU A;  5JG0 X;  3QLW A;  1J3I A;  4QHV A;  3NXO A;  4IXE D;  1DRB A;  2W9S A;  3DAT A;  3KFY A;  6DFR A;  3S3V A;  4FGH A;  4QLG A;  1DR6 A;  3F8Y A;  5EAJ A;  4KM0 A;  4DFR A;  4QLF A;  3ZPG A;  3QYL A;  1M7A A;  2B3Z A;  3F0X X;  1PDB A;  4KYA A;  3FL8 A;  4LAH X;  4OR7 A;  1DIS A;  3S9U A;  3FQ0 A;  2BL9 A;  2W3V A;  3JW3 A;  4IXF X;  3ZPC A;  4M7V A;  3JW5 A;  1RA9 A;  3K45 A;  4HA7 A;  4EIL A;  3GHC A;  4GH8 A;  4KFJ A;  4DDR A;  4XT8 A;  5ECC A;  5FDA A;  1CZ3 A;  3GI2 A;  4H96 A;  4Q6A A;  4QI9 A;  3FRF X;  3JWC A;  2JYB A;  1DYH A;  3DFR A;  3F0V X;  5U27 A;  4XT7 A;  1JUV A;  1J3J A;  1RB2 A;  4LEK X;  4KAK A;  1RX5 A;  4X5J A;  4HOE A;  2C2T A;  3FRD X;  3SH2 A;  2XW7 A;  3SRU X;  2DHF A;  4KJK A;  3TQ9 A;  2D0K A;  3SGY A;  1MVS A;  2OIP A;  3KY8 A;  3QL0 A;  1RB3 A;  1RH3 A;  2ITH A;  3IX9 A;  1LUD A;  1OHJ A;  4P66 A;  2CD2 A;  4KBN A;  5HI6 A;  1HFR A;  1DLS A;  4ELH A;  4KL9 A;  3F0S X;  4ELF A;  1KLK A;  4P68 A;  2D5N A;  2BLB A;  3Q1H A;  3OAF A;  3FQC A;  1AI9 A;  3NZA X;  3NTZ A;  4G95 A;  1RC4 A;  3TQ8 A;  1RE7 A;  3IA4 A;  4RGC A;  1DYR A;  2AZN A;  3NXT A;  1ZDR A;  1PD8 A;  4EIG A;  4DPD A;  1DRH A;  2CIG A;  4PSY A;  2KGK A;  5CC9 A;  5HT5 A;  3DGA A;  4KD7 A;  3JVX A;  3HBB A;  1QZF A;  5CCC A;  2W3A A;  1RD7 A;  4Q67 A;  3QLZ A;  3SRS X;  4LAG X;  3FQV A;  1KMV A;  1DR5 A;  4KNE A;  4NX7 A;  3UM8 A;  1MVT A;  2FZH A; 
#chains in the Genus database with same CATH homology
 5U26 A;  2HM9 A;  3KJR A;  1RA2 A;  2W3M A;  3IRM A;  3GYF A;  1DG5 A;  3ROA A;  1RX1 A;  4ECK A;  2L28 A;  4OSG A;  2C2S A;  3DL5 A;  4HA9 A;  1CD2 A;  1LY4 A;  4KEB A;  3JWF A;  1RX7 A;  1JOM A;  3JWK A;  3EEM A;  4QJZ D;  3TQA A;  3DRC A;  1RX9 A;  3D84 X;  1IA3 A;  3F0B X;  5HUI A;  2W9T A;  3FYW X;  1D1G A;  3SA1 A;  2W3W A;  1IA1 A;  1DR7 A;  1DR2 A;  1RA8 A;  1RF7 A;  1VDR A;  3TD8 A;  1RA1 A;  2HXV A;  3NZ6 X;  3M09 A;  4H98 A;  3SA2 A;  2INQ A;  1DR1 A;  4P3Q A;  1BOZ A;  4XEC X;  1DYJ A;  4IXG X;  5DXV A;  4PDJ A;  4X5G A;  3F0U X;  1PD9 A;  5HF0 X;  3SAI A;  5HVB A;  3CSE A;  3QG2 A;  3R33 A;  3CD2 A;  3K74 A;  4TU5 X;  1U70 A;  4KY4 A;  8DFR A;  1SEJ A;  4P3R A;  3KJS A;  3F0Q X;  3NXY A;  1AOE A;  5HPB A;  3QLX A;  4M6K A;  2QK8 A;  2FZI A;  4LAE X;  4M7U A;  1IA2 A;  4XE6 X;  3NZB X;  3SR5 X;  3M08 A;  3QGT A;  3RO9 A;  3DAU A;  3EEL A;  3L3R A;  1DG8 A;  1DRF A;  1HFP A;  3FY9 X;  4ELE A;  1DLR A;  1DHF A;  1S3W A;  1DR4 A;  2FZJ A;  3LG4 A;  3SRR X;  5HF2 X;  1DG7 A;  4X5I A;  3UM6 A;  5HQZ A;  4M6L A;  3QLS A;  2W9G A;  2ANO A;  2G6V A;  3N0H A;  2H2Q A;  3E0B A;  1HFQ A;  1IA4 A;  3NZC X;  3DG8 A;  5HQY A;  2HQP A;  1DDS A;  3QLY A;  1RG7 A;  1KMS A;  4DP3 A;  4KJL A;  4Q0E A;  4HOG A;  2P4G A;  4PST A;  5HVE A;  1RX3 A;  4G3M A;  1DYI A;  3F8Z A;  3KGY A;  3EEJ A;  3IA5 A;  4DPH A;  5DFR A;  2ZZA A;  4M6J A;  1J3K A;  1S3U A;  4H95 A;  4Q0D A;  1YHO A;  2O7P A;  4XRB A;  3QFX A;  3FRE X;  4KJJ A;  3CLB A;  1DDR A;  3I3R A;  4PTJ A;  3SRQ X;  1U71 A;  4I1N A;  3IRN A;  4EJ1 A;  3RG9 A;  1DR3 A;  3GHV A;  4XT6 A;  3EEK A;  2BLA A;  3F91 A;  3FS6 A;  2ANQ A;  4PTH A;  1S3V A;  2BLC A;  2LF1 A;  4QLE A;  1OHK A;  1DRE A;  5E8Q A;  1U72 A;  1JOL A;  2GD9 A;  1DHI A;  4NX6 A;  3IRO A;  4M2X A;  3NRR A;  3FY8 X;  3K2H A;  3NXV A;  4KY8 A;  1DIU A;  5HT4 A;  1BZF A;  3S7A A;  1DRA A;  4ELG A;  3TQB A;  3DL6 A;  1AO8 A;  3FL9 A;  3SRW X;  4XT5 A;  1RX8 A;  4I13 A;  1E26 A;  3INV A;  3QYO A;  2DRC A;  2W3B A;  3FYV X;  4FGG A;  3I8A X;  3HJ3 A;  5HSR A;  1RX2 A;  3UM5 A;  1M78 A;  3VCO A;  3NXR A;  1S3Y A;  3JWM A;  3NZD A;  1RX4 A;  1M79 A;  4HOF A;  1TDR A;  3FQF A;  3JSU A;  3FRB X;  1LY3 A;  4KM2 A;  1VJ3 A;  3OCH A;  7DFR A;  4CD2 A;  3FQO A;  3K47 A;  1DAJ A;  4H97 A;  1DHJ A;  2OBC A;  3QL3 A;  4QJC A;  3SQY X;  3GHW A;  5JA3 A;  4EIZ A;  3EX8 A;  3JTW A;  3FQZ A;  5ECX A;  3NZ9 X;  4ELB A;  3D80 A;  3EIG A;  4G8Z X;  3CL9 A;  3FRA X;  4X5F A;  4XT4 A;  1RX6 A;  4FHB A;  1RA3 A;  3NXX A;  4KLX A;  4X5H A;  3NU0 A;  1DF7 A;  4PSS A;  3QLR A;  2W9H A;  5HSU A;  5JG0 X;  3QLW A;  1J3I A;  4QHV A;  3NXO A;  4IXE D;  1DRB A;  2W9S A;  3DAT A;  3KFY A;  6DFR A;  3S3V A;  4FGH A;  4QLG A;  1DR6 A;  3F8Y A;  5EAJ A;  4KM0 A;  4DFR A;  4QLF A;  3ZPG A;  3QYL A;  1M7A A;  2B3Z A;  3F0X X;  1PDB A;  4KYA A;  3FL8 A;  4LAH X;  4OR7 A;  1DIS A;  3S9U A;  3FQ0 A;  2BL9 A;  2W3V A;  3JW3 A;  4IXF X;  3ZPC A;  4M7V A;  3JW5 A;  1RA9 A;  3K45 A;  4HA7 A;  4EIL A;  3GHC A;  4GH8 A;  4KFJ A;  4DDR A;  4XT8 A;  5ECC A;  5FDA A;  1CZ3 A;  3GI2 A;  4H96 A;  4Q6A A;  4QI9 A;  3FRF X;  3JWC A;  2JYB A;  1DYH A;  3DFR A;  3F0V X;  5U27 A;  4XT7 A;  1JUV A;  1J3J A;  1RB2 A;  4LEK X;  4KAK A;  1RX5 A;  4X5J A;  4HOE A;  2C2T A;  3FRD X;  3SH2 A;  2XW7 A;  3SRU X;  2DHF A;  4KJK A;  3TQ9 A;  2D0K A;  3SGY A;  1MVS A;  2OIP A;  3KY8 A;  3QL0 A;  1RB3 A;  1RH3 A;  2ITH A;  3IX9 A;  1LUD A;  1OHJ A;  4P66 A;  2CD2 A;  4KBN A;  5HI6 A;  1HFR A;  1DLS A;  4ELH A;  4KL9 A;  3F0S X;  4ELF A;  1KLK A;  4P68 A;  2D5N A;  2BLB A;  3Q1H A;  3OAF A;  3FQC A;  1AI9 A;  3NZA X;  3NTZ A;  4G95 A;  1RC4 A;  3TQ8 A;  1RE7 A;  3IA4 A;  4RGC A;  1DYR A;  2AZN A;  3NXT A;  1ZDR A;  1PD8 A;  4EIG A;  4DPD A;  1DRH A;  2CIG A;  4PSY A;  2KGK A;  5CC9 A;  5HT5 A;  3DGA A;  4KD7 A;  3JVX A;  3HBB A;  1QZF A;  5CCC A;  2W3A A;  1RD7 A;  4Q67 A;  3QLZ A;  3SRS X;  4LAG X;  3FQV A;  1KMV A;  1DR5 A;  4KNE A;  4NX7 A;  3UM8 A;  1MVT A;  2FZH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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