5I4ZA

Structure of apo omomyc
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
74
structure length
74
Chain Sequence
RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Myc proto-oncogene protein
total genus 30
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i4zA00
5I4ZA 4ATKA 2QL2A 1AN4A 1HLOA 5I50A 1AN2A 2MH3A 4F3LB 1AM9A 4ATHA 4H10B 2YPAA 4ATIA 4F3LA 4H10A 1UKLC 1A0AA 1MDYA 2YPBB 1NLWB 1R05A 1NKPB 2YPBA 2LFHA 1MDYB 4AYAA 2YPAB 1NKPA 3MUJA 1NLWA 2QL2B 5EYOA 3U5VA
chains in the Genus database with same CATH superfamily
5I4ZA 4ATKA 2QL2A 1AN4A 1HLOA 5I50A 1K1FA 1AN2A 2MH3A 4F3LB 1AM9A 4ATHA 4H10B 2YPAA 4ATIA 4F3LA 4H10A 1UKLC 1A0AA 1MDYA 2YPBB 1NLWB 1R05A 1NKPB 2YPBA 1ZZAA 2LFHA 4AYAA 1MDYB 2YPAB 1NKPA 3MUJA 1NLWA 2QL2B 5EYOA 3U5VA
chains in the Genus database with same CATH topology
5I4ZA 4ATKA 2QL2A 1AN4A 1HLOA 5I50A 1AN2A 2MH3A 4F3LB 1AM9A 4ATHA 4H10B 2YPAA 4ATIA 4F3LA 4H10A 1UKLC 1A0AA 1MDYA 2YPBB 1NLWB 1R05A 1NKPB 2YPBA 2LFHA 1MDYB 4AYAA 2YPAB 1NKPA 3MUJA 1NLWA 2QL2B 5EYOA 3U5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I4Z A;  4ATK A;  2QL2 A;  1AN4 A;  1HLO A;  5I50 A;  1AN2 A;  2MH3 A;  4F3L B;  1AM9 A;  4ATH A;  4H10 B;  2YPA A;  4ATI A;  4F3L A;  4H10 A;  1UKL C;  1A0A A;  1MDY A;  2YPB B;  1NLW B;  1R05 A;  1NKP B;  2YPB A;  2LFH A;  1MDY B;  4AYA A;  2YPA B;  1NKP A;  3MUJ A;  1NLW A;  2QL2 B;  5EYO A;  3U5V A; 
#chains in the Genus database with same CATH topology
 5I4Z A;  4ATK A;  2QL2 A;  1AN4 A;  1HLO A;  5I50 A;  1K1F A;  1AN2 A;  2MH3 A;  4F3L B;  1AM9 A;  4ATH A;  4H10 B;  2YPA A;  4ATI A;  4F3L A;  4H10 A;  1UKL C;  1A0A A;  1MDY A;  2YPB B;  1NLW B;  1R05 A;  1NKP B;  2YPB A;  1ZZA A;  2LFH A;  4AYA A;  1MDY B;  2YPA B;  1NKP A;  3MUJ A;  1NLW A;  2QL2 B;  5EYO A;  3U5V A; 
#chains in the Genus database with same CATH homology
 5I4Z A;  4ATK A;  2QL2 A;  1AN4 A;  1HLO A;  5I50 A;  1AN2 A;  2MH3 A;  4F3L B;  1AM9 A;  4ATH A;  4H10 B;  2YPA A;  4ATI A;  4F3L A;  4H10 A;  1UKL C;  1A0A A;  1MDY A;  2YPB B;  1NLW B;  1R05 A;  1NKP B;  2YPB A;  2LFH A;  1MDY B;  4AYA A;  2YPA B;  1NKP A;  3MUJ A;  1NLW A;  2QL2 B;  5EYO A;  3U5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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