5IFOA

X-ray structure of hsa-myr-kp1019
Total Genus 200
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
200
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 200
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2016-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA05
4HGMB 3LU8A 4G04A 1E7AA 2BXDA 4IW1A 1BM0A 3B9LA 2BXFA 4F5VA 4Z69A 4E99A 4N0FD 2BXQA 2I30A 1E7FA 4K2CA 1E7BA 2BXIA 5IIHA 4K71A 4N0UD 1HA2A 2BXEA 2XVQA 2VUFA 3A73A 1E7HA 3TDLA 3LU7A 1HK2A 5IFOA 1E7EA 5ID7A 5IIXA 1E7IA 1MA9A 4EMXA 1KW2A 2BXAA 4F5UA 4G03A 4L9KA 1H9ZA 2BXMA 2BXPA 1HK3A 3LU6A 1E78A 3V08A 4ZBQA 2VUEA 1J78A 5ID9A 1E7CA 4L8UA 5IIUA 2XSIA 2XVVA 4BKEA 5IJEA 1UORA 4HGKA 4F5TA 3JQZA 2XW1A 2BXHA 3JRYA 5IJFA 2BXLA 2BXGA 4IW2A 5GHKA 2XW0A 1GNJA 1HK4A 4LB9A 4ZBRA 4LA0A 4JK4A 1TF0A 4J2VA 2BXOA 1N5UA 2BX8A 1LOTA 2VDBA 1KXPD 1BJ5A 1O9XA 2BXBA 4S1YA 1HK5A 5HOZA 3CX9A 4LB2A 1BKEA 1GNIA 2XVWA 4LUHA 2YDFA 4OR0A 3V09A 5FUOA 1AO6A 2BXNA 4OT2A 2XVUA 2BXCA 3V03A 2I2ZA 1E7GA 4LUFA 1HK1A 5DQFA 1J7EA 5IJ5A 2BXKA 4PO0A 3B9MA 4F5SA 3SQJA 3UIVA 4L9QA 5DBYA
chains in the Genus database with same CATH superfamily
4FIPB 4HGMB 5GINA 3LU8A 4M70B 2GUTA 3FWCC 1MIVA 4G04A 4DHXB 1E7AA 2BXDA 1IJGA 3SIUB 4G01A 4IW1A 3A75A 2LQIA 2V36A 2DBXA 3NMUA 4I9OA 1BM0A 3B9LA 2BXFA 3NVMA 3ICXA 4F5VA 3GQXA 4OTUA 4E99A 4Z69A 4N0FD 2LQHA 3W1SA 3M99C 2BXQA 2I30A 4C31B 1E7FA 3PLAA 4K2CA 1E7BA 2BXIA 5IIHA 2Z8KA 3FNMA 3BPJA 4BY9C 4K71A 4N0UD 1HA2A 2BXEA 2XVQA 2VUFA 3A73A 1E7HA 2EFHA 2LXTA 2Z8JA 3TDLA 3LU7A 1HK2A 5IFOA 3VQIA 1E7EA 4GDXA 2XMOA 3G9KD 3KJLA 5ID7A 5IIXA 3MHSB 1E7IA 1MA9A 4OTTA 1MIYA 4EMXA 1KW2A 4GG2A 2BXAA 4F5UA 4G03A 2AJEA 2Z8IA 4MBEC 4ZCGA 2EFEA 4L9KA 2DBUA 1H9ZA 2BXMA 5GIPA 2DYOA 2BXPA 2AGHB 1HK3A 4ZC6A 2ROHA 4W4UB 3LU6A 2CKXA 2NQOA 1E78A 3V08A 4ZBQA 2VUEA 1J78A 4D7XA 5ID9A 3ECPA 2OZBB 1E7CA 1TXUA 4L8UA 3FWBC 3WHRA 5IIUA 2XSIA 4ZBKA 2DYMA 2XVVA 4GDLB 4BKEA 3WHQA 5IJEA 1JNBA 1UORA 2KBZA 4HGKA 1MUHA 4N3ZA 4F5TA 1FOUA 5GIOA 4DM0A 1VFIA 3JQZA 3GA9L 2KWFA 2XW1A 2DG5A 2QHBA 3SIVB 2BXHA 3JRYA 5IJFA 4FK5B 1LNSA 2BXLA 2BXGA 2DBWA 5D7GA 2OT3A 4IW2A 5GHKA 2XW0A 1GNJA 1HK4A 2QM6A 4LB9A 4NAWB 4ZBRA 4LA0A 3MHHB 4JK4A 5BPKA 1TF0A 4J2VA 3NVIA 4TQ1A 2BXOA 1N5UA 2BX8A 1LOTA 2VDBA 4Z9OA 1KXPD 1BJ5A 1O9XA 4GDKB 2BXBA 3H3AA 1MUSA 1KDXA 4S1YA 1HK5A 1AO6A 2JUHA 2K0NA 4FJCB 5HOZA 1MM8A 2EFCA 3CX9A 4LB2A 1BKEA 2LXSA 1VZSA 3WHSA 4ZUXV 1GNIA 2E0YA 2LOQA 4TQ0A 3KIKA 1SB0A 2XVWA 2QMCA 2YDFA 4LUHA 4OR0A 3V09A 2EFDA 2BXNA 4OT2A 5FUOA 2XVUA 3GQUA 2BXCA 3V03A 5B5TA 2I2ZA 1E7GA 2E0XA 4LUFA 1HK1A 5DQFA 1J7EA 5IJ5A 1MIWA 2BXKA 4PO0A 3NVKA 3B9MA 1NT2B 2NNWA 1H5WA 4WA6B 4F5SA 3H37A 3SQJA 3UIVA 4L9QA 5DBYA
chains in the Genus database with same CATH topology
4FIPB 4HGMB 5GINA 3LU8A 4M70B 3FWCC 1MIVA 4G04A 4DHXB 1E7AA 2BXDA 1IJGA 3SIUB 4G01A 4IW1A 3A75A 2V36A 2DBXA 3NMUA 1BM0A 3B9LA 2BXFA 3NVMA 3ICXA 4F5VA 3GQXA 4OTUA 4E99A 4Z69A 4N0FD 3W1SA 3M99C 2BXQA 2I30A 4C31B 1E7FA 3PLAA 4K2CA 1E7BA 2BXIA 5IIHA 2Z8KA 3FNMA 4BY9C 4K71A 4N0UD 1HA2A 2BXEA 2XVQA 2VUFA 3A73A 1E7HA 2EFHA 2Z8JA 3TDLA 3VQIA 3LU7A 1HK2A 5IFOA 1E7EA 4GDXA 2XMOA 3G9KD 3KJLA 5ID7A 5IIXA 3MHSB 1E7IA 1MA9A 4OTTA 1MIYA 4EMXA 1KW2A 4GG2A 2BXAA 4F5UA 4G03A 2AJEA 2Z8IA 4MBEC 4ZCGA 2EFEA 4L9KA 2DBUA 1H9ZA 2BXMA 5GIPA 2DYOA 2BXPA 1HK3A 4ZC6A 2ROHA 4W4UB 3LU6A 2CKXA 2NQOA 1E78A 3V08A 4ZBQA 2VUEA 1J78A 2OZBB 5ID9A 1E7CA 1TXUA 4L8UA 3FWBC 3WHRA 5IIUA 2XSIA 4ZBKA 2DYMA 2XVVA 4GDLB 4BKEA 3WHQA 5IJEA 1JNBA 1UORA 2KBZA 4HGKA 4N3ZA 4F5TA 1FOUA 5GIOA 1VFIA 3JQZA 3GA9L 2XW1A 2DG5A 2QHBA 3SIVB 2BXHA 3JRYA 5IJFA 4FK5B 1LNSA 2BXLA 2BXGA 2DBWA 5D7GA 2OT3A 4IW2A 5GHKA 2XW0A 1GNJA 1HK4A 2QM6A 4LB9A 4NAWB 4ZBRA 4LA0A 3MHHB 4JK4A 5BPKA 1TF0A 4J2VA 3NVIA 4TQ1A 2BXOA 1N5UA 2BX8A 1LOTA 2VDBA 4Z9OA 1KXPD 1BJ5A 1O9XA 4GDKB 2BXBA 3H3AA 4S1YA 1HK5A 1AO6A 2JUHA 4FJCB 5HOZA 2EFCA 3CX9A 4LB2A 1BKEA 1VZSA 3WHSA 4ZUXV 1GNIA 2E0YA 2LOQA 4TQ0A 3KIKA 2XVWA 2QMCA 2YDFA 4LUHA 4OR0A 3V09A 2EFDA 2BXNA 4OT2A 5FUOA 2XVUA 3GQUA 2BXCA 3V03A 5B5TA 2I2ZA 1E7GA 2E0XA 4LUFA 1HK1A 5DQFA 1J7EA 5IJ5A 1MIWA 2BXKA 4PO0A 3NVKA 3B9MA 1NT2B 2NNWA 1H5WA 4WA6B 4F5SA 3H37A 3SQJA 3UIVA 4L9QA 5DBYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HGM B;  3LU8 A;  4G04 A;  1E7A A;  2BXD A;  4IW1 A;  1BM0 A;  3B9L A;  2BXF A;  4F5V A;  4Z69 A;  4E99 A;  4N0F D;  2BXQ A;  2I30 A;  1E7F A;  4K2C A;  1E7B A;  2BXI A;  5IIH A;  4K71 A;  4N0U D;  1HA2 A;  2BXE A;  2XVQ A;  2VUF A;  3A73 A;  1E7H A;  3TDL A;  3LU7 A;  1HK2 A;  5IFO A;  1E7E A;  5ID7 A;  5IIX A;  1E7I A;  1MA9 A;  4EMX A;  1KW2 A;  2BXA A;  4F5U A;  4G03 A;  4L9K A;  1H9Z A;  2BXM A;  2BXP A;  1HK3 A;  3LU6 A;  1E78 A;  3V08 A;  4ZBQ A;  2VUE A;  1J78 A;  5ID9 A;  1E7C A;  4L8U A;  5IIU A;  2XSI A;  2XVV A;  4BKE A;  5IJE A;  1UOR A;  4HGK A;  4F5T A;  3JQZ A;  2XW1 A;  2BXH A;  3JRY A;  5IJF A;  2BXL A;  2BXG A;  4IW2 A;  5GHK A;  2XW0 A;  1GNJ A;  1HK4 A;  4LB9 A;  4ZBR A;  4LA0 A;  4JK4 A;  1TF0 A;  4J2V A;  2BXO A;  1N5U A;  2BX8 A;  1LOT A;  2VDB A;  1KXP D;  1BJ5 A;  1O9X A;  2BXB A;  4S1Y A;  1HK5 A;  5HOZ A;  3CX9 A;  4LB2 A;  1BKE A;  1GNI A;  2XVW A;  4LUH A;  2YDF A;  4OR0 A;  3V09 A;  5FUO A;  1AO6 A;  2BXN A;  4OT2 A;  2XVU A;  2BXC A;  3V03 A;  2I2Z A;  1E7G A;  4LUF A;  1HK1 A;  5DQF A;  1J7E A;  5IJ5 A;  2BXK A;  4PO0 A;  3B9M A;  4F5S A;  3SQJ A;  3UIV A;  4L9Q A;  5DBY A; 
#chains in the Genus database with same CATH topology
 4FIP B;  4HGM B;  5GIN A;  3LU8 A;  4M70 B;  2GUT A;  3FWC C;  1MIV A;  4G04 A;  4DHX B;  1E7A A;  2BXD A;  1IJG A;  3SIU B;  4G01 A;  4IW1 A;  3A75 A;  2LQI A;  2V36 A;  2DBX A;  3NMU A;  4I9O A;  1BM0 A;  3B9L A;  2BXF A;  3NVM A;  3ICX A;  4F5V A;  3GQX A;  4OTU A;  4E99 A;  4Z69 A;  4N0F D;  2LQH A;  3W1S A;  3M99 C;  2BXQ A;  2I30 A;  4C31 B;  1E7F A;  3PLA A;  4K2C A;  1E7B A;  2BXI A;  5IIH A;  2Z8K A;  3FNM A;  3BPJ A;  4BY9 C;  4K71 A;  4N0U D;  1HA2 A;  2BXE A;  2XVQ A;  2VUF A;  3A73 A;  1E7H A;  2EFH A;  2LXT A;  2Z8J A;  3TDL A;  3LU7 A;  1HK2 A;  5IFO A;  3VQI A;  1E7E A;  4GDX A;  2XMO A;  3G9K D;  3KJL A;  5ID7 A;  5IIX A;  3MHS B;  1E7I A;  1MA9 A;  4OTT A;  1MIY A;  4EMX A;  1KW2 A;  4GG2 A;  2BXA A;  4F5U A;  4G03 A;  2AJE A;  2Z8I A;  4MBE C;  4ZCG A;  2EFE A;  4L9K A;  2DBU A;  1H9Z A;  2BXM A;  5GIP A;  2DYO A;  2BXP A;  2AGH B;  1HK3 A;  4ZC6 A;  2ROH A;  4W4U B;  3LU6 A;  2CKX A;  2NQO A;  1E78 A;  3V08 A;  4ZBQ A;  2VUE A;  1J78 A;  4D7X A;  5ID9 A;  3ECP A;  2OZB B;  1E7C A;  1TXU A;  4L8U A;  3FWB C;  3WHR A;  5IIU A;  2XSI A;  4ZBK A;  2DYM A;  2XVV A;  4GDL B;  4BKE A;  3WHQ A;  5IJE A;  1JNB A;  1UOR A;  2KBZ A;  4HGK A;  1MUH A;  4N3Z A;  4F5T A;  1FOU A;  5GIO A;  4DM0 A;  1VFI A;  3JQZ A;  3GA9 L;  2KWF A;  2XW1 A;  2DG5 A;  2QHB A;  3SIV B;  2BXH A;  3JRY A;  5IJF A;  4FK5 B;  1LNS A;  2BXL A;  2BXG A;  2DBW A;  5D7G A;  2OT3 A;  4IW2 A;  5GHK A;  2XW0 A;  1GNJ A;  1HK4 A;  2QM6 A;  4LB9 A;  4NAW B;  4ZBR A;  4LA0 A;  3MHH B;  4JK4 A;  5BPK A;  1TF0 A;  4J2V A;  3NVI A;  4TQ1 A;  2BXO A;  1N5U A;  2BX8 A;  1LOT A;  2VDB A;  4Z9O A;  1KXP D;  1BJ5 A;  1O9X A;  4GDK B;  2BXB A;  3H3A A;  1MUS A;  1KDX A;  4S1Y A;  1HK5 A;  1AO6 A;  2JUH A;  2K0N A;  4FJC B;  5HOZ A;  1MM8 A;  2EFC A;  3CX9 A;  4LB2 A;  1BKE A;  2LXS A;  1VZS A;  3WHS A;  4ZUX V;  1GNI A;  2E0Y A;  2LOQ A;  4TQ0 A;  3KIK A;  1SB0 A;  2XVW A;  2QMC A;  2YDF A;  4LUH A;  4OR0 A;  3V09 A;  2EFD A;  2BXN A;  4OT2 A;  5FUO A;  2XVU A;  3GQU A;  2BXC A;  3V03 A;  5B5T A;  2I2Z A;  1E7G A;  2E0X A;  4LUF A;  1HK1 A;  5DQF A;  1J7E A;  5IJ5 A;  1MIW A;  2BXK A;  4PO0 A;  3NVK A;  3B9M A;  1NT2 B;  2NNW A;  1H5W A;  4WA6 B;  4F5S A;  3H37 A;  3SQJ A;  3UIV A;  4L9Q A;  5DBY A; 
#chains in the Genus database with same CATH homology
 4FIP B;  4HGM B;  5GIN A;  3LU8 A;  4M70 B;  3FWC C;  1MIV A;  4G04 A;  4DHX B;  1E7A A;  2BXD A;  1IJG A;  3SIU B;  4G01 A;  4IW1 A;  3A75 A;  2V36 A;  2DBX A;  3NMU A;  1BM0 A;  3B9L A;  2BXF A;  3NVM A;  3ICX A;  4F5V A;  3GQX A;  4OTU A;  4E99 A;  4Z69 A;  4N0F D;  3W1S A;  3M99 C;  2BXQ A;  2I30 A;  4C31 B;  1E7F A;  3PLA A;  4K2C A;  1E7B A;  2BXI A;  5IIH A;  2Z8K A;  3FNM A;  4BY9 C;  4K71 A;  4N0U D;  1HA2 A;  2BXE A;  2XVQ A;  2VUF A;  3A73 A;  1E7H A;  2EFH A;  2Z8J A;  3TDL A;  3VQI A;  3LU7 A;  1HK2 A;  5IFO A;  1E7E A;  4GDX A;  2XMO A;  3G9K D;  3KJL A;  5ID7 A;  5IIX A;  3MHS B;  1E7I A;  1MA9 A;  4OTT A;  1MIY A;  4EMX A;  1KW2 A;  4GG2 A;  2BXA A;  4F5U A;  4G03 A;  2AJE A;  2Z8I A;  4MBE C;  4ZCG A;  2EFE A;  4L9K A;  2DBU A;  1H9Z A;  2BXM A;  5GIP A;  2DYO A;  2BXP A;  1HK3 A;  4ZC6 A;  2ROH A;  4W4U B;  3LU6 A;  2CKX A;  2NQO A;  1E78 A;  3V08 A;  4ZBQ A;  2VUE A;  1J78 A;  2OZB B;  5ID9 A;  1E7C A;  1TXU A;  4L8U A;  3FWB C;  3WHR A;  5IIU A;  2XSI A;  4ZBK A;  2DYM A;  2XVV A;  4GDL B;  4BKE A;  3WHQ A;  5IJE A;  1JNB A;  1UOR A;  2KBZ A;  4HGK A;  4N3Z A;  4F5T A;  1FOU A;  5GIO A;  1VFI A;  3JQZ A;  3GA9 L;  2XW1 A;  2DG5 A;  2QHB A;  3SIV B;  2BXH A;  3JRY A;  5IJF A;  4FK5 B;  1LNS A;  2BXL A;  2BXG A;  2DBW A;  5D7G A;  2OT3 A;  4IW2 A;  5GHK A;  2XW0 A;  1GNJ A;  1HK4 A;  2QM6 A;  4LB9 A;  4NAW B;  4ZBR A;  4LA0 A;  3MHH B;  4JK4 A;  5BPK A;  1TF0 A;  4J2V A;  3NVI A;  4TQ1 A;  2BXO A;  1N5U A;  2BX8 A;  1LOT A;  2VDB A;  4Z9O A;  1KXP D;  1BJ5 A;  1O9X A;  4GDK B;  2BXB A;  3H3A A;  4S1Y A;  1HK5 A;  1AO6 A;  2JUH A;  4FJC B;  5HOZ A;  2EFC A;  3CX9 A;  4LB2 A;  1BKE A;  1VZS A;  3WHS A;  4ZUX V;  1GNI A;  2E0Y A;  2LOQ A;  4TQ0 A;  3KIK A;  2XVW A;  2QMC A;  2YDF A;  4LUH A;  4OR0 A;  3V09 A;  2EFD A;  2BXN A;  4OT2 A;  5FUO A;  2XVU A;  3GQU A;  2BXC A;  3V03 A;  5B5T A;  2I2Z A;  1E7G A;  2E0X A;  4LUF A;  1HK1 A;  5DQF A;  1J7E A;  5IJ5 A;  1MIW A;  2BXK A;  4PO0 A;  3NVK A;  3B9M A;  1NT2 B;  2NNW A;  1H5W A;  4WA6 B;  4F5S A;  3H37 A;  3SQJ A;  3UIV A;  4L9Q A;  5DBY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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