5JA3A

Mycobacterium tuberculosis dihydrofolate reductase complexed with beta- nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-b iphenyl]-4-carboxylic acid (ucp1106)
Total Genus 43
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
total genus 43
structure length 159
sequence length 159
chains with identical sequence B, C, D
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2016-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5ja3A00
3EEKA 1RX7A 4CD2A 1QZFA 5HPBA 3K2HA 1DRFA 3D84X 1DRHA 1KLKA 1E26A 3IA5A 3UM6A 1DRAA 4M7UA 1U72A 2O7PA 2CIGA 3QLZA 3SRRX 3IRMA 4H97A 4PSYA 4QLFA 4ELEA 3SA2A 3FS6A 5EAJA 3I3RA 4QLEA 3I8AX 4HOFA 1RX5A 1ZDRA 3JSUA 4RGCA 1IA2A 2G6VA 4H95A 3NZAX 3F0SX 3KJRA 1BOZA 3FL9A 3NXYA 5U27A 3EEMA 1RA8A 1OHKA 1LY4A 4HOGA 3NXVA 1D1GA 4PTJA 3N0HA 4Q0DA 3HBBA 3FY9X 1HFQA 3TQBA 4IXED 5CCCA 6DFRA 4KJLA 5DFRA 2C2TA 3R33A 5HUIA 3UM5A 4Q0EA 4KJKA 2OIPA 3FQCA 1RX8A 1RA1A 1DR3A 7DFRA 5HSUA 3CD2A 5U26A 1DAJA 3E0BA 4DDRA 1MVSA 4PSSA 1DHIA 1IA4A 3FRAX 4FHBA 2FZJA 1DHJA 3QLYA 3NXTA 3QGTA 3FYVX 3F8YA 1BZFA 4M6LA 4M2XA 5HT5A 1TDRA 4PDJA 1DR6A 2HQPA 4KEBA 1RA2A 3FYWX 3LG4A 3SRWX 5JA3A 3ZPGA 2BL9A 4KM0A 4KYAA 3F0BX 3OCHA 3K74A 4DP3A 5HF2X 1CZ3A 3DAUA 1DISA 1DDSA 1DR4A 1M79A 3FQZA 2W3AA 1J3IA 2JYBA 1DYRA 1VDRA 4XECX 1M78A 1PD8A 3L3RA 1DR2A 1PDBA 1RA3A 1RX4A 3SRQX 3DL6A 3S7AA 1IA3A 4XT4A 1RC4A 3SRSX 3EEJA 3CLBA 3QYOA 1RB2A 1JOLA 3KGYA 4KAKA 5E8QA 2FZIA 1RX6A 3SAIA 4M7VA 3QLXA 2W3WA 5FDAA 2W3BA 3F91A 4HA9A 3OAFA 4NX7A 4EILA 3TQ9A 4XE6X 5HI6A 1U70A 2ANOA 1DLSA 1DYIA 3Q1HA 3JTWA 3NU0A 3QFXA 4Q67A 3SA1A 1RX9A 1AO8A 1J3JA 3SGYA 3IX9A 1MVTA 3IRNA 4QHVA 3S9UA 3F0XX 3CSEA 4GH8A 1RG7A 4DPHA 1YHOA 1DHFA 3IROA 2BLBA 2QK8A 3SH2A 3NZDA 4KL9A 2W3VA 3NXOA 3SQYX 1RX2A 3JW5A 4KJJA 4FGGA 2HXVA 4P66A 3VCOA 2FZHA 3S3VA 4HA7A 3TD8A 1LY3A 1RA9A 3FQVA 3EX8A 2KGKA 4DFRA 4EIGA 4KM2A 4ELBA 3EELA 4IXGX 4X5IA 4QJCA 1VJ3A 5JG0X 2BLCA 3DL5A 3HJ3A 3QYLA 4G8ZX 1DF7A 4EJ1A 2W9TA 1DYHA 5HSRA 3JVXA 4KBNA 5HT4A 4NX6A 3KJSA 1IA1A 2C2SA 4LAHX 3QLWA 2L28A 4IXFX 4PTHA 2GD9A 3NZ6X 4X5GA 4H96A 3SRUX 2HM9A 5CC9A 3NTZA 4KY8A 3ROAA 3IA4A 4TU5X 3RO9A 1AI9A 1DRBA 2D5NA 1DIUA 3TQ8A 3SR5X 1U71A 4X5HA 4P3RA 1HFPA 3JWCA 1RX3A 3F0VX 3TQAA 2D0KA 2ITHA 4P68A 3FREX 3ZPCA 4X5FA 3FL8A 2INQA 3FQ0A 1KMSA 3QL0A 1RE7A 4Q6AA 3KFYA 1S3WA 4LAGX 1KMVA 1DG8A 4OR7A 2ZZAA 2H2QA 3F8ZA 4XT5A 3EIGA 3DFRA 4EIZA 4HOEA 3NXXA 1S3VA 2W9SA 1DG7A 2W9HA 4KFJA 1HFRA 4ELGA 2DHFA 4ELFA 4LEKX 1RF7A 5HQZA 4M6JA 4QI9A 4QJZD 1SEJA 5HVEA 1DLRA 4FGHA 1PD9A 4XT8A 2CD2A 1RH3A 3JW3A 2OBCA 4DPDA 2DRCA 3GHWA 5DXVA 3JWFA 5HQYA 2XW7A 4OSGA 3K45A 3DATA 3NZ9X 2ANQA 1DYJA 3QLRA 4KY4A 4H98A 1M7AA 1JUVA 3DGAA 3FRBX 4X5JA 4KD7A 4XT7A 3GYFA 3UM8A 1JOMA 3GHCA 2W9GA 3CL9A 4KLXA 4M6KA 1S3YA 1DR5A 1DDRA 3GI2A 2P4GA 1DREA 5ECXA 3NZBX 1LUDA 3F0UX 1RD7A 3D80A 5HVBA 4XRBA 1RB3A 2LF1A 3QG2A 4I13A 4ELHA 8DFRA 3JWMA 3K47A 4ECKA 3RG9A 2W3MA 3DG8A 2BLAA 1CD2A 3FY8X 3QL3A 3JWKA 3FRDX 4LAEX 4PSTA 5HF0X 1DR7A 1AOEA 3NZCX 3QLSA 4G95A 4G3MA 2B3ZA 5ECCA 1RX1A 3F0QX 3NRRA 1DG5A 3FRFX 4KNEA 3FQFA 3GHVA 3NXRA 4I1NA 3INVA 3M09A 4XT6A 4P3QA 1S3UA 3DRCA 4QLGA 1J3KA 2AZNA 1OHJA 3KY8A 3M08A 1DR1A 3FQOA
chains in the Genus database with same CATH superfamily
3EEKA 1RX7A 4CD2A 1QZFA 5HPBA 3K2HA 1DRFA 3D84X 1DRHA 1KLKA 1E26A 3IA5A 3UM6A 1DRAA 4M7UA 1U72A 2O7PA 2CIGA 3QLZA 3SRRX 3IRMA 4H97A 4PSYA 4QLFA 4ELEA 3SA2A 3FS6A 5EAJA 3I3RA 4QLEA 3I8AX 4HOFA 1RX5A 1ZDRA 3JSUA 4RGCA 1IA2A 2G6VA 4H95A 3NZAX 3F0SX 3KJRA 1BOZA 3FL9A 3NXYA 5U27A 3EEMA 1RA8A 1OHKA 1LY4A 4HOGA 3NXVA 1D1GA 4PTJA 3N0HA 4Q0DA 3HBBA 3FY9X 1HFQA 3TQBA 4IXED 5CCCA 6DFRA 4KJLA 5DFRA 2C2TA 3R33A 5HUIA 3UM5A 4Q0EA 4KJKA 2OIPA 3FQCA 1RX8A 1RA1A 1DR3A 7DFRA 5HSUA 3CD2A 5U26A 1DAJA 3E0BA 4DDRA 1MVSA 4PSSA 1DHIA 1IA4A 3FRAX 4FHBA 2FZJA 1DHJA 3QLYA 3NXTA 3QGTA 3FYVX 3F8YA 1BZFA 4M6LA 4M2XA 5HT5A 1TDRA 4PDJA 1DR6A 2HQPA 4KEBA 1RA2A 3FYWX 3LG4A 3SRWX 5JA3A 3ZPGA 2BL9A 4KM0A 4KYAA 3F0BX 3OCHA 3K74A 4DP3A 5HF2X 1CZ3A 3DAUA 1DISA 1DDSA 1DR4A 1M79A 3FQZA 2W3AA 1J3IA 2JYBA 1DYRA 1VDRA 4XECX 1M78A 1PD8A 3L3RA 1DR2A 1PDBA 1RA3A 1RX4A 3SRQX 3DL6A 3S7AA 1IA3A 4XT4A 1RC4A 3SRSX 3EEJA 3CLBA 3QYOA 1RB2A 1JOLA 3KGYA 4KAKA 5E8QA 2FZIA 1RX6A 3SAIA 4M7VA 3QLXA 2W3WA 5FDAA 2W3BA 3F91A 4HA9A 3OAFA 4NX7A 4EILA 3TQ9A 4XE6X 5HI6A 1U70A 2ANOA 1DLSA 1DYIA 3Q1HA 3JTWA 3NU0A 3QFXA 4Q67A 3SA1A 1RX9A 1AO8A 1J3JA 3SGYA 3IX9A 1MVTA 3IRNA 4QHVA 3S9UA 3F0XX 3CSEA 4GH8A 1RG7A 4DPHA 1YHOA 1DHFA 3IROA 2BLBA 2QK8A 3SH2A 3NZDA 4KL9A 2W3VA 3NXOA 3SQYX 1RX2A 3JW5A 4KJJA 4FGGA 2HXVA 4P66A 3VCOA 2FZHA 3S3VA 4HA7A 3TD8A 1LY3A 1RA9A 3FQVA 3EX8A 2KGKA 4DFRA 4EIGA 4KM2A 4ELBA 3EELA 4IXGX 4X5IA 4QJCA 1VJ3A 5JG0X 2BLCA 3DL5A 3HJ3A 3QYLA 4G8ZX 1DF7A 4EJ1A 2W9TA 1DYHA 5HSRA 3JVXA 4KBNA 5HT4A 4NX6A 3KJSA 1IA1A 2C2SA 4LAHX 3QLWA 2L28A 4IXFX 4PTHA 2GD9A 3NZ6X 4X5GA 4H96A 3SRUX 2HM9A 5CC9A 3NTZA 4KY8A 3ROAA 3IA4A 4TU5X 3RO9A 1AI9A 1DRBA 2D5NA 1DIUA 3TQ8A 3SR5X 1U71A 4X5HA 4P3RA 1HFPA 3JWCA 1RX3A 3F0VX 3TQAA 2D0KA 2ITHA 4P68A 3FREX 3ZPCA 4X5FA 3FL8A 2INQA 3FQ0A 1KMSA 3QL0A 1RE7A 4Q6AA 3KFYA 1S3WA 4LAGX 1KMVA 1DG8A 4OR7A 2ZZAA 2H2QA 3F8ZA 4XT5A 3EIGA 3DFRA 4EIZA 4HOEA 3NXXA 1S3VA 2W9SA 1DG7A 2W9HA 4KFJA 1HFRA 4ELGA 2DHFA 4ELFA 4LEKX 1RF7A 5HQZA 4M6JA 4QI9A 4QJZD 1SEJA 5HVEA 1DLRA 4FGHA 1PD9A 4XT8A 2CD2A 1RH3A 3JW3A 2OBCA 4DPDA 2DRCA 3GHWA 5DXVA 3JWFA 5HQYA 2XW7A 4OSGA 3K45A 3DATA 3NZ9X 2ANQA 1DYJA 3QLRA 4KY4A 4H98A 1M7AA 1JUVA 3DGAA 3FRBX 4X5JA 4KD7A 4XT7A 3GYFA 3UM8A 1JOMA 3GHCA 2W9GA 3CL9A 4KLXA 4M6KA 1S3YA 1DR5A 1DDRA 3GI2A 2P4GA 1DREA 5ECXA 3NZBX 1LUDA 3F0UX 1RD7A 3D80A 5HVBA 4XRBA 1RB3A 2LF1A 3QG2A 4I13A 4ELHA 8DFRA 3JWMA 3K47A 4ECKA 3RG9A 2W3MA 3DG8A 2BLAA 1CD2A 3FY8X 3QL3A 3JWKA 3FRDX 4LAEX 4PSTA 5HF0X 1DR7A 1AOEA 3NZCX 3QLSA 4G95A 4G3MA 2B3ZA 5ECCA 1RX1A 3F0QX 3NRRA 1DG5A 3FRFX 4KNEA 3FQFA 3GHVA 3NXRA 4I1NA 3INVA 3M09A 4XT6A 4P3QA 1S3UA 3DRCA 4QLGA 1J3KA 2AZNA 1OHJA 3KY8A 3M08A 1DR1A 3FQOA
chains in the Genus database with same CATH topology
3EEKA 1RX7A 4CD2A 1QZFA 5HPBA 3K2HA 1DRFA 3D84X 1DRHA 1KLKA 1E26A 3IA5A 3UM6A 1DRAA 4M7UA 1U72A 2O7PA 2CIGA 3QLZA 3SRRX 3IRMA 4H97A 4PSYA 4QLFA 4ELEA 3SA2A 3FS6A 5EAJA 3I3RA 4QLEA 3I8AX 4HOFA 1RX5A 1ZDRA 3JSUA 4RGCA 1IA2A 2G6VA 4H95A 3NZAX 3F0SX 3KJRA 1BOZA 3FL9A 3NXYA 5U27A 3EEMA 1RA8A 1OHKA 1LY4A 4HOGA 3NXVA 1D1GA 4PTJA 3N0HA 4Q0DA 3HBBA 3FY9X 1HFQA 3TQBA 4IXED 5CCCA 6DFRA 4KJLA 5DFRA 2C2TA 3R33A 5HUIA 3UM5A 4Q0EA 4KJKA 2OIPA 3FQCA 1RX8A 1RA1A 1DR3A 7DFRA 5HSUA 3CD2A 5U26A 1DAJA 3E0BA 4DDRA 1MVSA 4PSSA 1DHIA 1IA4A 3FRAX 4FHBA 2FZJA 1DHJA 3QLYA 3NXTA 3QGTA 3FYVX 3F8YA 1BZFA 4M6LA 4M2XA 5HT5A 1TDRA 4PDJA 1DR6A 2HQPA 4KEBA 1RA2A 3FYWX 3LG4A 3SRWX 5JA3A 3ZPGA 2BL9A 4KM0A 4KYAA 3F0BX 3OCHA 3K74A 4DP3A 5HF2X 1CZ3A 3DAUA 1DISA 1DDSA 1DR4A 1M79A 3FQZA 2W3AA 1J3IA 2JYBA 1DYRA 1VDRA 4XECX 1M78A 1PD8A 3L3RA 1DR2A 1PDBA 1RA3A 1RX4A 3SRQX 3DL6A 3S7AA 1IA3A 4XT4A 1RC4A 3SRSX 3EEJA 3CLBA 3QYOA 1RB2A 1JOLA 3KGYA 4KAKA 5E8QA 2FZIA 1RX6A 3SAIA 4M7VA 3QLXA 2W3WA 5FDAA 2W3BA 3F91A 4HA9A 3OAFA 4NX7A 4EILA 3TQ9A 4XE6X 5HI6A 1U70A 2ANOA 1DLSA 1DYIA 3Q1HA 3JTWA 3NU0A 3QFXA 4Q67A 3SA1A 1RX9A 1AO8A 1J3JA 3SGYA 3IX9A 1MVTA 3IRNA 4QHVA 3S9UA 3F0XX 3CSEA 4GH8A 1RG7A 4DPHA 1YHOA 1DHFA 3IROA 2BLBA 2QK8A 3SH2A 3NZDA 4KL9A 2W3VA 3NXOA 3SQYX 1RX2A 3JW5A 4KJJA 4FGGA 2HXVA 4P66A 3VCOA 2FZHA 3S3VA 4HA7A 3TD8A 1LY3A 1RA9A 3FQVA 3EX8A 2KGKA 4DFRA 4EIGA 4KM2A 4ELBA 3EELA 4IXGX 4X5IA 4QJCA 1VJ3A 5JG0X 2BLCA 3DL5A 3HJ3A 3QYLA 4G8ZX 1DF7A 4EJ1A 2W9TA 1DYHA 5HSRA 3JVXA 4KBNA 5HT4A 4NX6A 3KJSA 1IA1A 2C2SA 4LAHX 3QLWA 2L28A 4IXFX 4PTHA 2GD9A 3NZ6X 4X5GA 4H96A 3SRUX 2HM9A 5CC9A 3NTZA 4KY8A 3ROAA 3IA4A 4TU5X 3RO9A 1AI9A 1DRBA 2D5NA 1DIUA 3TQ8A 3SR5X 1U71A 4X5HA 4P3RA 1HFPA 3JWCA 1RX3A 3F0VX 3TQAA 2D0KA 2ITHA 4P68A 3FREX 3ZPCA 4X5FA 3FL8A 2INQA 3FQ0A 1KMSA 3QL0A 1RE7A 4Q6AA 3KFYA 1S3WA 4LAGX 1KMVA 1DG8A 4OR7A 2ZZAA 2H2QA 3F8ZA 4XT5A 3EIGA 3DFRA 4EIZA 4HOEA 3NXXA 1S3VA 2W9SA 1DG7A 2W9HA 4KFJA 1HFRA 4ELGA 2DHFA 4ELFA 4LEKX 1RF7A 5HQZA 4M6JA 4QI9A 4QJZD 1SEJA 5HVEA 1DLRA 4FGHA 1PD9A 4XT8A 2CD2A 1RH3A 3JW3A 2OBCA 4DPDA 2DRCA 3GHWA 5DXVA 3JWFA 5HQYA 2XW7A 4OSGA 3K45A 3DATA 3NZ9X 2ANQA 1DYJA 3QLRA 4KY4A 4H98A 1M7AA 1JUVA 3DGAA 3FRBX 4X5JA 4KD7A 4XT7A 3GYFA 3UM8A 1JOMA 3GHCA 2W9GA 3CL9A 4KLXA 4M6KA 1S3YA 1DR5A 1DDRA 3GI2A 2P4GA 1DREA 5ECXA 3NZBX 1LUDA 3F0UX 1RD7A 3D80A 5HVBA 4XRBA 1RB3A 2LF1A 3QG2A 4I13A 4ELHA 8DFRA 3JWMA 3K47A 4ECKA 3RG9A 2W3MA 3DG8A 2BLAA 1CD2A 3FY8X 3QL3A 3JWKA 3FRDX 4LAEX 4PSTA 5HF0X 1DR7A 1AOEA 3NZCX 3QLSA 4G95A 4G3MA 2B3ZA 5ECCA 1RX1A 3F0QX 3NRRA 1DG5A 3FRFX 4KNEA 3FQFA 3GHVA 3NXRA 4I1NA 3INVA 3M09A 4XT6A 4P3QA 1S3UA 3DRCA 4QLGA 1J3KA 2AZNA 1OHJA 3KY8A 3M08A 1DR1A 3FQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EEK A;  1RX7 A;  4CD2 A;  1QZF A;  5HPB A;  3K2H A;  1DRF A;  3D84 X;  1DRH A;  1KLK A;  1E26 A;  3IA5 A;  3UM6 A;  1DRA A;  4M7U A;  1U72 A;  2O7P A;  2CIG A;  3QLZ A;  3SRR X;  3IRM A;  4H97 A;  4PSY A;  4QLF A;  4ELE A;  3SA2 A;  3FS6 A;  5EAJ A;  3I3R A;  4QLE A;  3I8A X;  4HOF A;  1RX5 A;  1ZDR A;  3JSU A;  4RGC A;  1IA2 A;  2G6V A;  4H95 A;  3NZA X;  3F0S X;  3KJR A;  1BOZ A;  3FL9 A;  3NXY A;  5U27 A;  3EEM A;  1RA8 A;  1OHK A;  1LY4 A;  4HOG A;  3NXV A;  1D1G A;  4PTJ A;  3N0H A;  4Q0D A;  3HBB A;  3FY9 X;  1HFQ A;  3TQB A;  4IXE D;  5CCC A;  6DFR A;  4KJL A;  5DFR A;  2C2T A;  3R33 A;  5HUI A;  3UM5 A;  4Q0E A;  4KJK A;  2OIP A;  3FQC A;  1RX8 A;  1RA1 A;  1DR3 A;  7DFR A;  5HSU A;  3CD2 A;  5U26 A;  1DAJ A;  3E0B A;  4DDR A;  1MVS A;  4PSS A;  1DHI A;  1IA4 A;  3FRA X;  4FHB A;  2FZJ A;  1DHJ A;  3QLY A;  3NXT A;  3QGT A;  3FYV X;  3F8Y A;  1BZF A;  4M6L A;  4M2X A;  5HT5 A;  1TDR A;  4PDJ A;  1DR6 A;  2HQP A;  4KEB A;  1RA2 A;  3FYW X;  3LG4 A;  3SRW X;  5JA3 A;  3ZPG A;  2BL9 A;  4KM0 A;  4KYA A;  3F0B X;  3OCH A;  3K74 A;  4DP3 A;  5HF2 X;  1CZ3 A;  3DAU A;  1DIS A;  1DDS A;  1DR4 A;  1M79 A;  3FQZ A;  2W3A A;  1J3I A;  2JYB A;  1DYR A;  1VDR A;  4XEC X;  1M78 A;  1PD8 A;  3L3R A;  1DR2 A;  1PDB A;  1RA3 A;  1RX4 A;  3SRQ X;  3DL6 A;  3S7A A;  1IA3 A;  4XT4 A;  1RC4 A;  3SRS X;  3EEJ A;  3CLB A;  3QYO A;  1RB2 A;  1JOL A;  3KGY A;  4KAK A;  5E8Q A;  2FZI A;  1RX6 A;  3SAI A;  4M7V A;  3QLX A;  2W3W A;  5FDA A;  2W3B A;  3F91 A;  4HA9 A;  3OAF A;  4NX7 A;  4EIL A;  3TQ9 A;  4XE6 X;  5HI6 A;  1U70 A;  2ANO A;  1DLS A;  1DYI A;  3Q1H A;  3JTW A;  3NU0 A;  3QFX A;  4Q67 A;  3SA1 A;  1RX9 A;  1AO8 A;  1J3J A;  3SGY A;  3IX9 A;  1MVT A;  3IRN A;  4QHV A;  3S9U A;  3F0X X;  3CSE A;  4GH8 A;  1RG7 A;  4DPH A;  1YHO A;  1DHF A;  3IRO A;  2BLB A;  2QK8 A;  3SH2 A;  3NZD A;  4KL9 A;  2W3V A;  3NXO A;  3SQY X;  1RX2 A;  3JW5 A;  4KJJ A;  4FGG A;  2HXV A;  4P66 A;  3VCO A;  2FZH A;  3S3V A;  4HA7 A;  3TD8 A;  1LY3 A;  1RA9 A;  3FQV A;  3EX8 A;  2KGK A;  4DFR A;  4EIG A;  4KM2 A;  4ELB A;  3EEL A;  4IXG X;  4X5I A;  4QJC A;  1VJ3 A;  5JG0 X;  2BLC A;  3DL5 A;  3HJ3 A;  3QYL A;  4G8Z X;  1DF7 A;  4EJ1 A;  2W9T A;  1DYH A;  5HSR A;  3JVX A;  4KBN A;  5HT4 A;  4NX6 A;  3KJS A;  1IA1 A;  2C2S A;  4LAH X;  3QLW A;  2L28 A;  4IXF X;  4PTH A;  2GD9 A;  3NZ6 X;  4X5G A;  4H96 A;  3SRU X;  2HM9 A;  5CC9 A;  3NTZ A;  4KY8 A;  3ROA A;  3IA4 A;  4TU5 X;  3RO9 A;  1AI9 A;  1DRB A;  2D5N A;  1DIU A;  3TQ8 A;  3SR5 X;  1U71 A;  4X5H A;  4P3R A;  1HFP A;  3JWC A;  1RX3 A;  3F0V X;  3TQA A;  2D0K A;  2ITH A;  4P68 A;  3FRE X;  3ZPC A;  4X5F A;  3FL8 A;  2INQ A;  3FQ0 A;  1KMS A;  3QL0 A;  1RE7 A;  4Q6A A;  3KFY A;  1S3W A;  4LAG X;  1KMV A;  1DG8 A;  4OR7 A;  2ZZA A;  2H2Q A;  3F8Z A;  4XT5 A;  3EIG A;  3DFR A;  4EIZ A;  4HOE A;  3NXX A;  1S3V A;  2W9S A;  1DG7 A;  2W9H A;  4KFJ A;  1HFR A;  4ELG A;  2DHF A;  4ELF A;  4LEK X;  1RF7 A;  5HQZ A;  4M6J A;  4QI9 A;  4QJZ D;  1SEJ A;  5HVE A;  1DLR A;  4FGH A;  1PD9 A;  4XT8 A;  2CD2 A;  1RH3 A;  3JW3 A;  2OBC A;  4DPD A;  2DRC A;  3GHW A;  5DXV A;  3JWF A;  5HQY A;  2XW7 A;  4OSG A;  3K45 A;  3DAT A;  3NZ9 X;  2ANQ A;  1DYJ A;  3QLR A;  4KY4 A;  4H98 A;  1M7A A;  1JUV A;  3DGA A;  3FRB X;  4X5J A;  4KD7 A;  4XT7 A;  3GYF A;  3UM8 A;  1JOM A;  3GHC A;  2W9G A;  3CL9 A;  4KLX A;  4M6K A;  1S3Y A;  1DR5 A;  1DDR A;  3GI2 A;  2P4G A;  1DRE A;  5ECX A;  3NZB X;  1LUD A;  3F0U X;  1RD7 A;  3D80 A;  5HVB A;  4XRB A;  1RB3 A;  2LF1 A;  3QG2 A;  4I13 A;  4ELH A;  8DFR A;  3JWM A;  3K47 A;  4ECK A;  3RG9 A;  2W3M A;  3DG8 A;  2BLA A;  1CD2 A;  3FY8 X;  3QL3 A;  3JWK A;  3FRD X;  4LAE X;  4PST A;  5HF0 X;  1DR7 A;  1AOE A;  3NZC X;  3QLS A;  4G95 A;  4G3M A;  2B3Z A;  5ECC A;  1RX1 A;  3F0Q X;  3NRR A;  1DG5 A;  3FRF X;  4KNE A;  3FQF A;  3GHV A;  3NXR A;  4I1N A;  3INV A;  3M09 A;  4XT6 A;  4P3Q A;  1S3U A;  3DRC A;  4QLG A;  1J3K A;  2AZN A;  1OHJ A;  3KY8 A;  3M08 A;  1DR1 A;  3FQO A; 
#chains in the Genus database with same CATH topology
 3EEK A;  1RX7 A;  4CD2 A;  1QZF A;  5HPB A;  3K2H A;  1DRF A;  3D84 X;  1DRH A;  1KLK A;  1E26 A;  3IA5 A;  3UM6 A;  1DRA A;  4M7U A;  1U72 A;  2O7P A;  2CIG A;  3QLZ A;  3SRR X;  3IRM A;  4H97 A;  4PSY A;  4QLF A;  4ELE A;  3SA2 A;  3FS6 A;  5EAJ A;  3I3R A;  4QLE A;  3I8A X;  4HOF A;  1RX5 A;  1ZDR A;  3JSU A;  4RGC A;  1IA2 A;  2G6V A;  4H95 A;  3NZA X;  3F0S X;  3KJR A;  1BOZ A;  3FL9 A;  3NXY A;  5U27 A;  3EEM A;  1RA8 A;  1OHK A;  1LY4 A;  4HOG A;  3NXV A;  1D1G A;  4PTJ A;  3N0H A;  4Q0D A;  3HBB A;  3FY9 X;  1HFQ A;  3TQB A;  4IXE D;  5CCC A;  6DFR A;  4KJL A;  5DFR A;  2C2T A;  3R33 A;  5HUI A;  3UM5 A;  4Q0E A;  4KJK A;  2OIP A;  3FQC A;  1RX8 A;  1RA1 A;  1DR3 A;  7DFR A;  5HSU A;  3CD2 A;  5U26 A;  1DAJ A;  3E0B A;  4DDR A;  1MVS A;  4PSS A;  1DHI A;  1IA4 A;  3FRA X;  4FHB A;  2FZJ A;  1DHJ A;  3QLY A;  3NXT A;  3QGT A;  3FYV X;  3F8Y A;  1BZF A;  4M6L A;  4M2X A;  5HT5 A;  1TDR A;  4PDJ A;  1DR6 A;  2HQP A;  4KEB A;  1RA2 A;  3FYW X;  3LG4 A;  3SRW X;  5JA3 A;  3ZPG A;  2BL9 A;  4KM0 A;  4KYA A;  3F0B X;  3OCH A;  3K74 A;  4DP3 A;  5HF2 X;  1CZ3 A;  3DAU A;  1DIS A;  1DDS A;  1DR4 A;  1M79 A;  3FQZ A;  2W3A A;  1J3I A;  2JYB A;  1DYR A;  1VDR A;  4XEC X;  1M78 A;  1PD8 A;  3L3R A;  1DR2 A;  1PDB A;  1RA3 A;  1RX4 A;  3SRQ X;  3DL6 A;  3S7A A;  1IA3 A;  4XT4 A;  1RC4 A;  3SRS X;  3EEJ A;  3CLB A;  3QYO A;  1RB2 A;  1JOL A;  3KGY A;  4KAK A;  5E8Q A;  2FZI A;  1RX6 A;  3SAI A;  4M7V A;  3QLX A;  2W3W A;  5FDA A;  2W3B A;  3F91 A;  4HA9 A;  3OAF A;  4NX7 A;  4EIL A;  3TQ9 A;  4XE6 X;  5HI6 A;  1U70 A;  2ANO A;  1DLS A;  1DYI A;  3Q1H A;  3JTW A;  3NU0 A;  3QFX A;  4Q67 A;  3SA1 A;  1RX9 A;  1AO8 A;  1J3J A;  3SGY A;  3IX9 A;  1MVT A;  3IRN A;  4QHV A;  3S9U A;  3F0X X;  3CSE A;  4GH8 A;  1RG7 A;  4DPH A;  1YHO A;  1DHF A;  3IRO A;  2BLB A;  2QK8 A;  3SH2 A;  3NZD A;  4KL9 A;  2W3V A;  3NXO A;  3SQY X;  1RX2 A;  3JW5 A;  4KJJ A;  4FGG A;  2HXV A;  4P66 A;  3VCO A;  2FZH A;  3S3V A;  4HA7 A;  3TD8 A;  1LY3 A;  1RA9 A;  3FQV A;  3EX8 A;  2KGK A;  4DFR A;  4EIG A;  4KM2 A;  4ELB A;  3EEL A;  4IXG X;  4X5I A;  4QJC A;  1VJ3 A;  5JG0 X;  2BLC A;  3DL5 A;  3HJ3 A;  3QYL A;  4G8Z X;  1DF7 A;  4EJ1 A;  2W9T A;  1DYH A;  5HSR A;  3JVX A;  4KBN A;  5HT4 A;  4NX6 A;  3KJS A;  1IA1 A;  2C2S A;  4LAH X;  3QLW A;  2L28 A;  4IXF X;  4PTH A;  2GD9 A;  3NZ6 X;  4X5G A;  4H96 A;  3SRU X;  2HM9 A;  5CC9 A;  3NTZ A;  4KY8 A;  3ROA A;  3IA4 A;  4TU5 X;  3RO9 A;  1AI9 A;  1DRB A;  2D5N A;  1DIU A;  3TQ8 A;  3SR5 X;  1U71 A;  4X5H A;  4P3R A;  1HFP A;  3JWC A;  1RX3 A;  3F0V X;  3TQA A;  2D0K A;  2ITH A;  4P68 A;  3FRE X;  3ZPC A;  4X5F A;  3FL8 A;  2INQ A;  3FQ0 A;  1KMS A;  3QL0 A;  1RE7 A;  4Q6A A;  3KFY A;  1S3W A;  4LAG X;  1KMV A;  1DG8 A;  4OR7 A;  2ZZA A;  2H2Q A;  3F8Z A;  4XT5 A;  3EIG A;  3DFR A;  4EIZ A;  4HOE A;  3NXX A;  1S3V A;  2W9S A;  1DG7 A;  2W9H A;  4KFJ A;  1HFR A;  4ELG A;  2DHF A;  4ELF A;  4LEK X;  1RF7 A;  5HQZ A;  4M6J A;  4QI9 A;  4QJZ D;  1SEJ A;  5HVE A;  1DLR A;  4FGH A;  1PD9 A;  4XT8 A;  2CD2 A;  1RH3 A;  3JW3 A;  2OBC A;  4DPD A;  2DRC A;  3GHW A;  5DXV A;  3JWF A;  5HQY A;  2XW7 A;  4OSG A;  3K45 A;  3DAT A;  3NZ9 X;  2ANQ A;  1DYJ A;  3QLR A;  4KY4 A;  4H98 A;  1M7A A;  1JUV A;  3DGA A;  3FRB X;  4X5J A;  4KD7 A;  4XT7 A;  3GYF A;  3UM8 A;  1JOM A;  3GHC A;  2W9G A;  3CL9 A;  4KLX A;  4M6K A;  1S3Y A;  1DR5 A;  1DDR A;  3GI2 A;  2P4G A;  1DRE A;  5ECX A;  3NZB X;  1LUD A;  3F0U X;  1RD7 A;  3D80 A;  5HVB A;  4XRB A;  1RB3 A;  2LF1 A;  3QG2 A;  4I13 A;  4ELH A;  8DFR A;  3JWM A;  3K47 A;  4ECK A;  3RG9 A;  2W3M A;  3DG8 A;  2BLA A;  1CD2 A;  3FY8 X;  3QL3 A;  3JWK A;  3FRD X;  4LAE X;  4PST A;  5HF0 X;  1DR7 A;  1AOE A;  3NZC X;  3QLS A;  4G95 A;  4G3M A;  2B3Z A;  5ECC A;  1RX1 A;  3F0Q X;  3NRR A;  1DG5 A;  3FRF X;  4KNE A;  3FQF A;  3GHV A;  3NXR A;  4I1N A;  3INV A;  3M09 A;  4XT6 A;  4P3Q A;  1S3U A;  3DRC A;  4QLG A;  1J3K A;  2AZN A;  1OHJ A;  3KY8 A;  3M08 A;  1DR1 A;  3FQO A; 
#chains in the Genus database with same CATH homology
 3EEK A;  1RX7 A;  4CD2 A;  1QZF A;  5HPB A;  3K2H A;  1DRF A;  3D84 X;  1DRH A;  1KLK A;  1E26 A;  3IA5 A;  3UM6 A;  1DRA A;  4M7U A;  1U72 A;  2O7P A;  2CIG A;  3QLZ A;  3SRR X;  3IRM A;  4H97 A;  4PSY A;  4QLF A;  4ELE A;  3SA2 A;  3FS6 A;  5EAJ A;  3I3R A;  4QLE A;  3I8A X;  4HOF A;  1RX5 A;  1ZDR A;  3JSU A;  4RGC A;  1IA2 A;  2G6V A;  4H95 A;  3NZA X;  3F0S X;  3KJR A;  1BOZ A;  3FL9 A;  3NXY A;  5U27 A;  3EEM A;  1RA8 A;  1OHK A;  1LY4 A;  4HOG A;  3NXV A;  1D1G A;  4PTJ A;  3N0H A;  4Q0D A;  3HBB A;  3FY9 X;  1HFQ A;  3TQB A;  4IXE D;  5CCC A;  6DFR A;  4KJL A;  5DFR A;  2C2T A;  3R33 A;  5HUI A;  3UM5 A;  4Q0E A;  4KJK A;  2OIP A;  3FQC A;  1RX8 A;  1RA1 A;  1DR3 A;  7DFR A;  5HSU A;  3CD2 A;  5U26 A;  1DAJ A;  3E0B A;  4DDR A;  1MVS A;  4PSS A;  1DHI A;  1IA4 A;  3FRA X;  4FHB A;  2FZJ A;  1DHJ A;  3QLY A;  3NXT A;  3QGT A;  3FYV X;  3F8Y A;  1BZF A;  4M6L A;  4M2X A;  5HT5 A;  1TDR A;  4PDJ A;  1DR6 A;  2HQP A;  4KEB A;  1RA2 A;  3FYW X;  3LG4 A;  3SRW X;  5JA3 A;  3ZPG A;  2BL9 A;  4KM0 A;  4KYA A;  3F0B X;  3OCH A;  3K74 A;  4DP3 A;  5HF2 X;  1CZ3 A;  3DAU A;  1DIS A;  1DDS A;  1DR4 A;  1M79 A;  3FQZ A;  2W3A A;  1J3I A;  2JYB A;  1DYR A;  1VDR A;  4XEC X;  1M78 A;  1PD8 A;  3L3R A;  1DR2 A;  1PDB A;  1RA3 A;  1RX4 A;  3SRQ X;  3DL6 A;  3S7A A;  1IA3 A;  4XT4 A;  1RC4 A;  3SRS X;  3EEJ A;  3CLB A;  3QYO A;  1RB2 A;  1JOL A;  3KGY A;  4KAK A;  5E8Q A;  2FZI A;  1RX6 A;  3SAI A;  4M7V A;  3QLX A;  2W3W A;  5FDA A;  2W3B A;  3F91 A;  4HA9 A;  3OAF A;  4NX7 A;  4EIL A;  3TQ9 A;  4XE6 X;  5HI6 A;  1U70 A;  2ANO A;  1DLS A;  1DYI A;  3Q1H A;  3JTW A;  3NU0 A;  3QFX A;  4Q67 A;  3SA1 A;  1RX9 A;  1AO8 A;  1J3J A;  3SGY A;  3IX9 A;  1MVT A;  3IRN A;  4QHV A;  3S9U A;  3F0X X;  3CSE A;  4GH8 A;  1RG7 A;  4DPH A;  1YHO A;  1DHF A;  3IRO A;  2BLB A;  2QK8 A;  3SH2 A;  3NZD A;  4KL9 A;  2W3V A;  3NXO A;  3SQY X;  1RX2 A;  3JW5 A;  4KJJ A;  4FGG A;  2HXV A;  4P66 A;  3VCO A;  2FZH A;  3S3V A;  4HA7 A;  3TD8 A;  1LY3 A;  1RA9 A;  3FQV A;  3EX8 A;  2KGK A;  4DFR A;  4EIG A;  4KM2 A;  4ELB A;  3EEL A;  4IXG X;  4X5I A;  4QJC A;  1VJ3 A;  5JG0 X;  2BLC A;  3DL5 A;  3HJ3 A;  3QYL A;  4G8Z X;  1DF7 A;  4EJ1 A;  2W9T A;  1DYH A;  5HSR A;  3JVX A;  4KBN A;  5HT4 A;  4NX6 A;  3KJS A;  1IA1 A;  2C2S A;  4LAH X;  3QLW A;  2L28 A;  4IXF X;  4PTH A;  2GD9 A;  3NZ6 X;  4X5G A;  4H96 A;  3SRU X;  2HM9 A;  5CC9 A;  3NTZ A;  4KY8 A;  3ROA A;  3IA4 A;  4TU5 X;  3RO9 A;  1AI9 A;  1DRB A;  2D5N A;  1DIU A;  3TQ8 A;  3SR5 X;  1U71 A;  4X5H A;  4P3R A;  1HFP A;  3JWC A;  1RX3 A;  3F0V X;  3TQA A;  2D0K A;  2ITH A;  4P68 A;  3FRE X;  3ZPC A;  4X5F A;  3FL8 A;  2INQ A;  3FQ0 A;  1KMS A;  3QL0 A;  1RE7 A;  4Q6A A;  3KFY A;  1S3W A;  4LAG X;  1KMV A;  1DG8 A;  4OR7 A;  2ZZA A;  2H2Q A;  3F8Z A;  4XT5 A;  3EIG A;  3DFR A;  4EIZ A;  4HOE A;  3NXX A;  1S3V A;  2W9S A;  1DG7 A;  2W9H A;  4KFJ A;  1HFR A;  4ELG A;  2DHF A;  4ELF A;  4LEK X;  1RF7 A;  5HQZ A;  4M6J A;  4QI9 A;  4QJZ D;  1SEJ A;  5HVE A;  1DLR A;  4FGH A;  1PD9 A;  4XT8 A;  2CD2 A;  1RH3 A;  3JW3 A;  2OBC A;  4DPD A;  2DRC A;  3GHW A;  5DXV A;  3JWF A;  5HQY A;  2XW7 A;  4OSG A;  3K45 A;  3DAT A;  3NZ9 X;  2ANQ A;  1DYJ A;  3QLR A;  4KY4 A;  4H98 A;  1M7A A;  1JUV A;  3DGA A;  3FRB X;  4X5J A;  4KD7 A;  4XT7 A;  3GYF A;  3UM8 A;  1JOM A;  3GHC A;  2W9G A;  3CL9 A;  4KLX A;  4M6K A;  1S3Y A;  1DR5 A;  1DDR A;  3GI2 A;  2P4G A;  1DRE A;  5ECX A;  3NZB X;  1LUD A;  3F0U X;  1RD7 A;  3D80 A;  5HVB A;  4XRB A;  1RB3 A;  2LF1 A;  3QG2 A;  4I13 A;  4ELH A;  8DFR A;  3JWM A;  3K47 A;  4ECK A;  3RG9 A;  2W3M A;  3DG8 A;  2BLA A;  1CD2 A;  3FY8 X;  3QL3 A;  3JWK A;  3FRD X;  4LAE X;  4PST A;  5HF0 X;  1DR7 A;  1AOE A;  3NZC X;  3QLS A;  4G95 A;  4G3M A;  2B3Z A;  5ECC A;  1RX1 A;  3F0Q X;  3NRR A;  1DG5 A;  3FRF X;  4KNE A;  3FQF A;  3GHV A;  3NXR A;  4I1N A;  3INV A;  3M09 A;  4XT6 A;  4P3Q A;  1S3U A;  3DRC A;  4QLG A;  1J3K A;  2AZN A;  1OHJ A;  3KY8 A;  3M08 A;  1DR1 A;  3FQO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...