5KA8A

Protein tyrosine phosphatase 1b l192a mutant, open state
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
289
structure length
289
Chain Sequence
GHMASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFANFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 105
structure length 289
sequence length 289
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka8A00
3QCNA 2CJZA 3V0DA 4GE6A 2PT0A 3O4SA 1D5RA 4WOHA 3V0IA 5IBMA 1T49A 1XM2A 2QDCA 1G7FA 2QDPA 3D44A 5K9WA 4KYRA 1T48A 4R0SA 4ERCA 3M4UA 1LQFA 4IKCA 2NLKA 2B3OA 5LXQB 3QCMA 4ZRTA 1OEUA 2RF6A 1L8KA 5MMZB 3QCIA 2J17A 3RGOA 4ICZA 4JNBA 4QAHA 2CM8A 2F70A 3D1OA 1G4US 2FH7A 2HNPA 4GS0A 4GFUA 2BGDA 4J51A 2J16B 3BRHA 4JMKA 1OHCA 3O5XA 4ZN5A 1YGUA 2NZ6A 2I3UA 5K9VA 3V0JA 2IMGA 4BJOA 4WU2A 2I6JA 1NWLA 2R0BA 1KAKA 1V3AA 2H4GA 2F6ZA 4GRYA 1PTVA 5I6VA 3ZV2A 1NO6A 1KAVA 1Q1MA 4NWFA 3BLUA 3QCJA 3U96A 2WGPA 4QBEA 5KA2A 2M3VA 3QCGA 5K24A 4DGXA 2B4OA 2ZMMA 4GFVA 2I75A 3S3HA 4TVVA 3QCDA 2CFVA 2HB1A 2F6FA 1C87A 1L8GA 3QCLA 4RH5A 2C46A 2H03A 2CM2A 2HCMA 1RPMA 1YWFA 1ZZWA 4KI9A 5EHPA 1ZCLA 3RZ2A 3A5JA 3D9CA 1VHRA 2FJNA 1RXDA 5J8RA 2QBPA 5BUGA 3V0EA 2C7SA 5KACA 2I4EA 2B4UA 1U24A 5KAAA 5KA9A 4WU3A 3EZZA 5KA4A 2NTAA 3PS5A 1X24A 4OHDA 5BX1A 1WAXA 1ECVA 1OEVA 5HDEA 1WCHA 3RGQA 3S3EA 4OHEA 2QCJA 2CMBA 2DXPA 2CM7A 3QKQA 1I57A 4NYHA 1Q6TA 3QCKA 4HJPA 4JBCA 2CNGA 1C84A 1J4XA 3EU0A 1XXVA 2H02A 3S4EA 2QDMA 2F6WA 3V0GA 3V0FA 1PTUA 2Y96A 4B04A 2GJTA 4PYHA 3F9AA 3GXHA 2G59A 2OZ5A 2I4GA 4YR8B 1NZ7A 2I5XA 3QCFA 2QBQA 2GWOA 1G7GA 3LJ8A 4ZI4A 3QCCA 2BV5A 5KADA 3V0HA 2MBCA 3EAXA 4WTYA 2A3KA 4GWFA 4I8NA 1XBOA 2HC2A 1EENA 1LARA 4RI4A 2CM3A 3I80A 2QCTA 1G4WR 3AWGA 2CMAA 3O3LA 1P15A 5IBSA 3NMEA 2Y2FA 3F99A 4DGPA 5KA7A 1A5YA 2QEPA 1FPRA 3F81A 1Q6SA 4QUMA 4KYQA 2CNFA 3EB1A 4NX8A 2HC1A 4MBBA 2F6VA 5BZZA 4S0GA 4PVGA 5KABA 3BLTA 3D42A 1YN9A 2H04A 3SR9A 1JLNA 4R30A 1QXKA 4H1OA 2BIJA 1OETA 5AWXA 1U25A 1YTNA 2HVLA 4R0TA 2OOQA 1BZHA 2PI7A 2CNIA 2ESBA 4AZ1A 4RI5A 1EEOA 2I6PA 1YGRA 2FJMA 1NL9A 2I6OA 2AHSA 5K23A 2VEVA 1ONYA 4QAPA 4NWGA 1SUGA 4RDDA 3ZM0A 3I36A 1NNYA 2YDUA 1G1HA 1BZJA 1G1FA 2H4KA 1PTYA 4RKKA 1NWEA 1ZCKA 4D3RA 2CNEA 4Z6BA 1PA1A 4OHHA 4GRZA 3ZM1A 2PBNA 4BPCA 5K25A 5KA1A 1PXHA 1PTTA 4GE2A 5K22A 4NNDA 1M3GA 3D1QA 1I9TA 1LYVA 3CM3A 2F71A 1OEOX 4H34A 2I3RA 3S3KA 3AWEA 4OHIA 4D3PA 2NT2A 5EHRA 1BZCA 2JJDA 2PA5A 4OHLA 1PA9A 1XRIA 2I6IA 2PSZA 2VEWA 3CWEA 2PQ5A 3S4OA 2I4HA 4Y2EA 1MKPA 1ONZA 2P4DA 3QKPA 5KA3A 4HJQA 2QBSA 5M43A 2VEUA 1OHDA 4RH9A 1YPTA 1C88A 2HY3A 4D3QA 3QCBA 3EMUA 1I9SA 2H4VA 2GP0A 2QBRA 5GTJA 4HRFA 2VEYA 3F41A 1GFYA 1QZ0A 1JF7A 2NV5A 3O4TA 3S3FA 2A8BA 3BM8A 2F46A 2F6TA 1G1GA 2B4PA 2I1YA 1Q6MA 3MOZA 3MOWA 3MMJA 2B4SA 3RO1A 3D1HA 2OUDA 3ZMQA 2AZRA 3OLRA 3SMEA 4GE5A 3I7ZA 1C83A 2B49A 2I6MA 2G6ZA 1OESA 1Q6PA 1WRMA 3N0AA 3OMHA 3ZM3A 3F9BA 1XXPA 3H2XA 1YZ4A 1FQ1A 3AWFA 2HXPA 4QBWA 1ZC0A 1Q6JA 2I42A 2Q47A 3ZM2A 3B7OA 1U26A 1YTWA 1YTSA 2P6XA 2SHPA 3QCEA 2CMCA 2HNQA 4Y14A 2BGEA 1OHEA 3GXGA 4RHGA 1PH0A 5KA0A 2BZLA 1AAXA 2CNHA 2J16A 3ZMPA 1C86A 4YAAA 1C85A 1R6HA 2B07A 1Q6NA 4QUNA 2VEXA 2E0TA 2OC3A 1FPZA 2F6YA 2ZN7A 2Q05A 3O4UA 1GWZA 1T4JA 2NT7A 1PYNA 1YFOA 5KA8A 4JMJA 5BZXA 1OEMX 3A5KA 3QCHA
chains in the Genus database with same CATH superfamily
3QCNA 2CJZA 3V0DA 3UAGA 4GE6A 2PT0A 3O4SA 1D5RA 4WOHA 3V0IA 5IBMA 1T49A 1XM2A 5A5FA 2F00A 2QDCA 1G7FA 2QDPA 3D44A 5K9WA 4KYRA 1T48A 4R0SA 4ERCA 3M4UA 3N2AA 1LQFA 2AM1A 4IKCA 2NLKA 2B3OA 5LXQB 4QF5A 2GCAA 3QCMA 1OEUA 4ZRTA 4CVKA 2RF6A 1L8KA 5MMZB 3QCIA 2J17A 3RGOA 4ICZA 4JNBA 2XJAA 4QAHA 2UAGA 2CM8A 2F70A 3D1OA 1G4US 2FH7A 2HNPA 4C13A 4GS0A 4GFUA 2BGDA 4J51A 2J16B 3BRHA 1E0DA 2VORA 4JMKA 1OHCA 3O5XA 4ZN5A 1YGUA 2NZ6A 2I3UA 5K9VA 3V0JA 2IMGA 4BJOA 4WU2A 2I6JA 1NWLA 2R0BA 1KAKA 1V3AA 2H4GA 2F6ZA 4GRYA 1PTVA 1UAGA 5I6VA 3ZV2A 1NO6A 1KAVA 1Q1MA 4NWFA 3BLUA 3QCJA 3U96A 2WGPA 4QBEA 5KA2A 2X5OA 2M3VA 3QCGA 5K24A 4DGXA 2B4OA 2ZMMA 4GFVA 2I75A 3S3HA 4TVVA 3QCDA 2CFVA 1GQQA 2HB1A 2F6FA 1C87A 1L8GA 3QCLA 1JBWA 4RH5A 2C46A 1W78A 2AM2A 2H03A 2CM2A 2WJPA 2HCMA 1RPMA 1YWFA 1ZZWA 2Y66A 4KI9A 5EHPA 1ZCLA 3RZ2A 3A5JA 3ZL8A 3D9CA 1VHRA 2FJNA 2Y67A 1RXDA 5J8RA 1P3DA 2QBPA 5BUGA 3V0EA 2C7SA 5KACA 2I4EA 2B4UA 1U24A 5KAAA 5KA9A 4WU3A 3EZZA 5KA4A 2NTAA 2GC6A 3PS5A 1X24A 4OHDA 5BX1A 1WAXA 1ECVA 1OEVA 5HDEA 1WCHA 2Y1OA 2GC5A 3RGQA 3S3EA 4OHEA 2QCJA 2CMBA 2DXPA 2CM7A 3QKQA 1I57A 4NYHA 1Q6TA 3QCKA 4BUBA 4HJPA 4JBCA 2CNGA 1C84A 1J4XA 3EU0A 1XXVA 2H02A 1J6UA 1FGSA 3S4EA 2QDMA 2F6WA 3V0GA 3V0FA 1PTUA 2Y96A 4B04A 4HV4A 2GJTA 4PYHA 3F9AA 3GXHA 2G59A 2OZ5A 2I4GA 4YR8B 1NZ7A 2I5XA 3QCFA 2QBQA 2GWOA 2UUOA 1G7GA 3LJ8A 4ZI4A 3QCCA 2BV5A 5KADA 3V0HA 2MBCA 3EAXA 4WTYA 2A3KA 4GWFA 4I8NA 1XBOA 2HC2A 1EENA 1LARA 4RI4A 2CM3A 3I80A 2QCTA 1G4WR 3LK7A 3AWGA 3PYZA 2CMAA 2UUPA 3O3LA 1P15A 5IBSA 3NMEA 2Y2FA 3F99A 4DGPA 5KA7A 1A5YA 2QEPA 1FPRA 3F81A 1Q6SA 4QUMA 4KYQA 2CNFA 3EB1A 4NX8A 2HC1A 4MBBA 2F6VA 5BZZA 2XPCA 4S0GA 4PVGA 4BUCA 5KABA 3BLTA 3D42A 1YN9A 2H04A 5A5EA 3SR9A 1JLNA 4R30A 1E8CA 1QXKA 4H1OA 2BIJA 1OETA 5AWXA 1U25A 1YTNA 2HVLA 4R0TA 2OOQA 1BZHA 1GQYA 2PI7A 2CNIA 2ESBA 4AZ1A 4RI5A 1EEOA 2I6PA 1YGRA 2FJMA 1NL9A 2I6OA 2AHSA 4CVMA 5K23A 2VEVA 1ONYA 4QAPA 4NWGA 1SUGA 4RDDA 3ZM0A 3I36A 1NNYA 1W7KA 1G1HA 2YDUA 4CVLA 3ZM5A 1BZJA 1G1FA 2H4KA 1GG4A 1PTYA 4RKKA 1NWEA 1ZCKA 4D3RA 2CNEA 4Z6BA 1PA1A 4OHHA 2JFGA 4GRZA 3ZM1A 2PBNA 4BPCA 5K25A 5KA1A 1PXHA 1PTTA 4GE2A 5K22A 4NNDA 1M3GA 3D1QA 3ZM6A 1I9TA 1LYVA 3CM3A 2F71A 1OEOX 4H34A 2I3RA 3S3KA 3AWEA 4OHIA 4D3PA 1O5ZA 3NRSA 2NT2A 5EHRA 1BZCA 2JJDA 2PA5A 1P31A 4OHLA 1PA9A 1XRIA 2I6IA 2PSZA 2VEWA 3CWEA 3QCZA 2PQ5A 3S4OA 1EEHA 2I4HA 4C12A 4Y2EA 1MKPA 1ONZA 2P4DA 3QKPA 5KA3A 4HJQA 2Y68A 4ZIYA 2QBSA 5M43A 2VEUA 1OHDA 4QDIA 4RH9A 1YPTA 1C88A 2HY3A 4D3QA 3QCBA 2JFHA 3EMUA 1I9SA 2H4VA 2GP0A 1JBVA 2QBRA 5GTJA 4HRFA 2VEYA 3F41A 3MVNA 1GFYA 1QZ0A 1JF7A 2NV5A 3O4TA 3S3FA 2A8BA 3BM8A 2F46A 3HN7A 2F6TA 2JFFA 1G1GA 2B4PA 2I1YA 1Q6MA 3MOZA 3MOWA 3MMJA 2B4SA 3RO1A 3D1HA 2OUDA 3ZMQA 2AZRA 2GCBA 3OLRA 3SMEA 4GE5A 2VTDA 3I7ZA 1C83A 2B49A 2I6MA 2G6ZA 1OESA 1Q6PA 1WRMA 3N0AA 3OMHA 3ZM3A 3F9BA 1XXPA 3H2XA 1YZ4A 1FQ1A 2WTZA 3AWFA 2HXPA 4QBWA 1ZC0A 1Q6JA 2I42A 2Q47A 2VOSA 3ZM2A 3B7OA 1U26A 1YTWA 1YTSA 2P6XA 2SHPA 3QCEA 2CMCA 2HNQA 4Y14A 2BGEA 1OHEA 3GXGA 4RHGA 1PH0A 5KA0A 2BZLA 1AAXA 2CNHA 2J16A 3ZMPA 1C86A 4YAAA 1C85A 1R6HA 2B07A 1Q6NA 4QUNA 2VEXA 2E0TA 2OC3A 1FPZA 2F6YA 2ZN7A 4UAGA 2Q05A 3O4UA 1GWZA 1T4JA 2NT7A 1PYNA 1YFOA 5KA8A 4JMJA 5BZXA 1OEMX 3A5KA 3QCHA 2VTEA
chains in the Genus database with same CATH topology
3QCNA 2CJZA 3V0DA 4GE6A 2PT0A 3O4SA 1D5RA 4WOHA 3V0IA 5IBMA 1T49A 1XM2A 2QDCA 1G7FA 2QDPA 3D44A 5K9WA 4KYRA 1T48A 4R0SA 4ERCA 3M4UA 1LQFA 4IKCA 2NLKA 2B3OA 5LXQB 3QCMA 4ZRTA 1OEUA 2RF6A 1L8KA 5MMZB 3QCIA 2J17A 3RGOA 4ICZA 4JNBA 4QAHA 2CM8A 2F70A 3D1OA 1G4US 2FH7A 2HNPA 4GS0A 4GFUA 2BGDA 4J51A 2J16B 3BRHA 4JMKA 1OHCA 3O5XA 4ZN5A 1YGUA 2NZ6A 2I3UA 5K9VA 3V0JA 2IMGA 4BJOA 4WU2A 2I6JA 1NWLA 2R0BA 1KAKA 1V3AA 2H4GA 2F6ZA 4GRYA 1PTVA 5I6VA 3ZV2A 1NO6A 1KAVA 1Q1MA 4NWFA 3BLUA 3QCJA 3U96A 2WGPA 4QBEA 5KA2A 2M3VA 3QCGA 5K24A 4DGXA 2B4OA 2ZMMA 4GFVA 2I75A 3S3HA 4TVVA 3QCDA 2CFVA 2HB1A 2F6FA 1C87A 1L8GA 3QCLA 4RH5A 2C46A 2H03A 2CM2A 2HCMA 1RPMA 1YWFA 1ZZWA 4KI9A 5EHPA 1ZCLA 3RZ2A 3A5JA 3D9CA 1VHRA 2FJNA 1RXDA 5J8RA 2QBPA 5BUGA 3V0EA 2C7SA 5KACA 2I4EA 2B4UA 1U24A 5KAAA 5KA9A 4WU3A 3EZZA 5KA4A 2NTAA 3PS5A 1X24A 4OHDA 5BX1A 1WAXA 1ECVA 1OEVA 5HDEA 1WCHA 3RGQA 3S3EA 4OHEA 2QCJA 2CMBA 2DXPA 2CM7A 3QKQA 1I57A 4NYHA 1Q6TA 3QCKA 4HJPA 4JBCA 2CNGA 1C84A 1J4XA 3EU0A 1XXVA 2H02A 3S4EA 2QDMA 2F6WA 3V0GA 3V0FA 1PTUA 2Y96A 4B04A 2GJTA 4PYHA 3F9AA 3GXHA 2G59A 2OZ5A 2I4GA 4YR8B 1NZ7A 2I5XA 3QCFA 2QBQA 2GWOA 1G7GA 3LJ8A 4ZI4A 3QCCA 2BV5A 5KADA 3V0HA 2MBCA 3EAXA 4WTYA 2A3KA 4GWFA 4I8NA 1XBOA 2HC2A 1EENA 1LARA 4RI4A 2CM3A 3I80A 2QCTA 1G4WR 3AWGA 2CMAA 3O3LA 1P15A 5IBSA 3NMEA 2Y2FA 3F99A 4DGPA 5KA7A 1A5YA 2QEPA 1FPRA 3F81A 1Q6SA 4QUMA 4KYQA 2CNFA 3EB1A 4NX8A 2HC1A 4MBBA 2F6VA 5BZZA 4S0GA 4PVGA 5KABA 3BLTA 3D42A 1YN9A 2H04A 3SR9A 1JLNA 4R30A 1QXKA 4H1OA 2BIJA 1OETA 5AWXA 1U25A 1YTNA 2HVLA 4R0TA 2OOQA 1BZHA 2PI7A 2CNIA 2ESBA 4AZ1A 4RI5A 1EEOA 2I6PA 1YGRA 2FJMA 1NL9A 2I6OA 2AHSA 5K23A 2VEVA 1ONYA 4QAPA 4NWGA 1SUGA 4RDDA 3ZM0A 3I36A 1NNYA 2YDUA 1G1HA 1BZJA 1G1FA 2H4KA 1PTYA 4RKKA 1NWEA 1ZCKA 4D3RA 2CNEA 4Z6BA 1PA1A 4OHHA 4GRZA 3ZM1A 2PBNA 4BPCA 5K25A 5KA1A 1PXHA 1PTTA 4GE2A 5K22A 4NNDA 1M3GA 3D1QA 1I9TA 1LYVA 3CM3A 2F71A 1OEOX 4H34A 2I3RA 3S3KA 3AWEA 4OHIA 4D3PA 2NT2A 5EHRA 1BZCA 2JJDA 2PA5A 4OHLA 1PA9A 1XRIA 2I6IA 2PSZA 2VEWA 3CWEA 2PQ5A 3S4OA 2I4HA 4Y2EA 1MKPA 1ONZA 2P4DA 3QKPA 5KA3A 4HJQA 2QBSA 5M43A 2VEUA 1OHDA 4RH9A 1YPTA 1C88A 2HY3A 4D3QA 3QCBA 3EMUA 1I9SA 2H4VA 2GP0A 2QBRA 5GTJA 4HRFA 2VEYA 3F41A 1GFYA 1QZ0A 1JF7A 2NV5A 3O4TA 3S3FA 2A8BA 3BM8A 2F46A 2F6TA 1G1GA 2B4PA 2I1YA 1Q6MA 3MOZA 3MOWA 3MMJA 2B4SA 3RO1A 3D1HA 2OUDA 3ZMQA 2AZRA 3OLRA 3SMEA 4GE5A 3I7ZA 1C83A 2B49A 2I6MA 2G6ZA 1OESA 1Q6PA 1WRMA 3N0AA 3OMHA 3ZM3A 3F9BA 1XXPA 3H2XA 1YZ4A 1FQ1A 3AWFA 2HXPA 4QBWA 1ZC0A 1Q6JA 2I42A 2Q47A 3ZM2A 3B7OA 1U26A 1YTWA 1YTSA 2P6XA 2SHPA 3QCEA 2CMCA 2HNQA 4Y14A 2BGEA 1OHEA 3GXGA 4RHGA 1PH0A 5KA0A 2BZLA 1AAXA 2CNHA 2J16A 3ZMPA 1C86A 4YAAA 1C85A 1R6HA 2B07A 1Q6NA 4QUNA 2VEXA 2E0TA 2OC3A 1FPZA 2F6YA 2ZN7A 2Q05A 3O4UA 1GWZA 1T4JA 2NT7A 1PYNA 1YFOA 5KA8A 4JMJA 5BZXA 1OEMX 3A5KA 3QCHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCN A;  2CJZ A;  3V0D A;  4GE6 A;  2PT0 A;  3O4S A;  1D5R A;  4WOH A;  3V0I A;  5IBM A;  1T49 A;  1XM2 A;  2QDC A;  1G7F A;  2QDP A;  3D44 A;  5K9W A;  4KYR A;  1T48 A;  4R0S A;  4ERC A;  3M4U A;  1LQF A;  4IKC A;  2NLK A;  2B3O A;  5LXQ B;  3QCM A;  4ZRT A;  1OEU A;  2RF6 A;  1L8K A;  5MMZ B;  3QCI A;  2J17 A;  3RGO A;  4ICZ A;  4JNB A;  4QAH A;  2CM8 A;  2F70 A;  3D1O A;  1G4U S;  2FH7 A;  2HNP A;  4GS0 A;  4GFU A;  2BGD A;  4J51 A;  2J16 B;  3BRH A;  4JMK A;  1OHC A;  3O5X A;  4ZN5 A;  1YGU A;  2NZ6 A;  2I3U A;  5K9V A;  3V0J A;  2IMG A;  4BJO A;  4WU2 A;  2I6J A;  1NWL A;  2R0B A;  1KAK A;  1V3A A;  2H4G A;  2F6Z A;  4GRY A;  1PTV A;  5I6V A;  3ZV2 A;  1NO6 A;  1KAV A;  1Q1M A;  4NWF A;  3BLU A;  3QCJ A;  3U96 A;  2WGP A;  4QBE A;  5KA2 A;  2M3V A;  3QCG A;  5K24 A;  4DGX A;  2B4O A;  2ZMM A;  4GFV A;  2I75 A;  3S3H A;  4TVV A;  3QCD A;  2CFV A;  2HB1 A;  2F6F A;  1C87 A;  1L8G A;  3QCL A;  4RH5 A;  2C46 A;  2H03 A;  2CM2 A;  2HCM A;  1RPM A;  1YWF A;  1ZZW A;  4KI9 A;  5EHP A;  1ZCL A;  3RZ2 A;  3A5J A;  3D9C A;  1VHR A;  2FJN A;  1RXD A;  5J8R A;  2QBP A;  5BUG A;  3V0E A;  2C7S A;  5KAC A;  2I4E A;  2B4U A;  1U24 A;  5KAA A;  5KA9 A;  4WU3 A;  3EZZ A;  5KA4 A;  2NTA A;  3PS5 A;  1X24 A;  4OHD A;  5BX1 A;  1WAX A;  1ECV A;  1OEV A;  5HDE A;  1WCH A;  3RGQ A;  3S3E A;  4OHE A;  2QCJ A;  2CMB A;  2DXP A;  2CM7 A;  3QKQ A;  1I57 A;  4NYH A;  1Q6T A;  3QCK A;  4HJP A;  4JBC A;  2CNG A;  1C84 A;  1J4X A;  3EU0 A;  1XXV A;  2H02 A;  3S4E A;  2QDM A;  2F6W A;  3V0G A;  3V0F A;  1PTU A;  2Y96 A;  4B04 A;  2GJT A;  4PYH A;  3F9A A;  3GXH A;  2G59 A;  2OZ5 A;  2I4G A;  4YR8 B;  1NZ7 A;  2I5X A;  3QCF A;  2QBQ A;  2GWO A;  1G7G A;  3LJ8 A;  4ZI4 A;  3QCC A;  2BV5 A;  5KAD A;  3V0H A;  2MBC A;  3EAX A;  4WTY A;  2A3K A;  4GWF A;  4I8N A;  1XBO A;  2HC2 A;  1EEN A;  1LAR A;  4RI4 A;  2CM3 A;  3I80 A;  2QCT A;  1G4W R;  3AWG A;  2CMA A;  3O3L A;  1P15 A;  5IBS A;  3NME A;  2Y2F A;  3F99 A;  4DGP A;  5KA7 A;  1A5Y A;  2QEP A;  1FPR A;  3F81 A;  1Q6S A;  4QUM A;  4KYQ A;  2CNF A;  3EB1 A;  4NX8 A;  2HC1 A;  4MBB A;  2F6V A;  5BZZ A;  4S0G A;  4PVG A;  5KAB A;  3BLT A;  3D42 A;  1YN9 A;  2H04 A;  3SR9 A;  1JLN A;  4R30 A;  1QXK A;  4H1O A;  2BIJ A;  1OET A;  5AWX A;  1U25 A;  1YTN A;  2HVL A;  4R0T A;  2OOQ A;  1BZH A;  2PI7 A;  2CNI A;  2ESB A;  4AZ1 A;  4RI5 A;  1EEO A;  2I6P A;  1YGR A;  2FJM A;  1NL9 A;  2I6O A;  2AHS A;  5K23 A;  2VEV A;  1ONY A;  4QAP A;  4NWG A;  1SUG A;  4RDD A;  3ZM0 A;  3I36 A;  1NNY A;  2YDU A;  1G1H A;  1BZJ A;  1G1F A;  2H4K A;  1PTY A;  4RKK A;  1NWE A;  1ZCK A;  4D3R A;  2CNE A;  4Z6B A;  1PA1 A;  4OHH A;  4GRZ A;  3ZM1 A;  2PBN A;  4BPC A;  5K25 A;  5KA1 A;  1PXH A;  1PTT A;  4GE2 A;  5K22 A;  4NND A;  1M3G A;  3D1Q A;  1I9T A;  1LYV A;  3CM3 A;  2F71 A;  1OEO X;  4H34 A;  2I3R A;  3S3K A;  3AWE A;  4OHI A;  4D3P A;  2NT2 A;  5EHR A;  1BZC A;  2JJD A;  2PA5 A;  4OHL A;  1PA9 A;  1XRI A;  2I6I A;  2PSZ A;  2VEW A;  3CWE A;  2PQ5 A;  3S4O A;  2I4H A;  4Y2E A;  1MKP A;  1ONZ A;  2P4D A;  3QKP A;  5KA3 A;  4HJQ A;  2QBS A;  5M43 A;  2VEU A;  1OHD A;  4RH9 A;  1YPT A;  1C88 A;  2HY3 A;  4D3Q A;  3QCB A;  3EMU A;  1I9S A;  2H4V A;  2GP0 A;  2QBR A;  5GTJ A;  4HRF A;  2VEY A;  3F41 A;  1GFY A;  1QZ0 A;  1JF7 A;  2NV5 A;  3O4T A;  3S3F A;  2A8B A;  3BM8 A;  2F46 A;  2F6T A;  1G1G A;  2B4P A;  2I1Y A;  1Q6M A;  3MOZ A;  3MOW A;  3MMJ A;  2B4S A;  3RO1 A;  3D1H A;  2OUD A;  3ZMQ A;  2AZR A;  3OLR A;  3SME A;  4GE5 A;  3I7Z A;  1C83 A;  2B49 A;  2I6M A;  2G6Z A;  1OES A;  1Q6P A;  1WRM A;  3N0A A;  3OMH A;  3ZM3 A;  3F9B A;  1XXP A;  3H2X A;  1YZ4 A;  1FQ1 A;  3AWF A;  2HXP A;  4QBW A;  1ZC0 A;  1Q6J A;  2I42 A;  2Q47 A;  3ZM2 A;  3B7O A;  1U26 A;  1YTW A;  1YTS A;  2P6X A;  2SHP A;  3QCE A;  2CMC A;  2HNQ A;  4Y14 A;  2BGE A;  1OHE A;  3GXG A;  4RHG A;  1PH0 A;  5KA0 A;  2BZL A;  1AAX A;  2CNH A;  2J16 A;  3ZMP A;  1C86 A;  4YAA A;  1C85 A;  1R6H A;  2B07 A;  1Q6N A;  4QUN A;  2VEX A;  2E0T A;  2OC3 A;  1FPZ A;  2F6Y A;  2ZN7 A;  2Q05 A;  3O4U A;  1GWZ A;  1T4J A;  2NT7 A;  1PYN A;  1YFO A;  5KA8 A;  4JMJ A;  5BZX A;  1OEM X;  3A5K A;  3QCH A; 
#chains in the Genus database with same CATH topology
 3QCN A;  2CJZ A;  3V0D A;  3UAG A;  4GE6 A;  2PT0 A;  3O4S A;  1D5R A;  4WOH A;  3V0I A;  5IBM A;  1T49 A;  1XM2 A;  5A5F A;  2F00 A;  2QDC A;  1G7F A;  2QDP A;  3D44 A;  5K9W A;  4KYR A;  1T48 A;  4R0S A;  4ERC A;  3M4U A;  3N2A A;  1LQF A;  2AM1 A;  4IKC A;  2NLK A;  2B3O A;  5LXQ B;  4QF5 A;  2GCA A;  3QCM A;  1OEU A;  4ZRT A;  4CVK A;  2RF6 A;  1L8K A;  5MMZ B;  3QCI A;  2J17 A;  3RGO A;  4ICZ A;  4JNB A;  2XJA A;  4QAH A;  2UAG A;  2CM8 A;  2F70 A;  3D1O A;  1G4U S;  2FH7 A;  2HNP A;  4C13 A;  4GS0 A;  4GFU A;  2BGD A;  4J51 A;  2J16 B;  3BRH A;  1E0D A;  2VOR A;  4JMK A;  1OHC A;  3O5X A;  4ZN5 A;  1YGU A;  2NZ6 A;  2I3U A;  5K9V A;  3V0J A;  2IMG A;  4BJO A;  4WU2 A;  2I6J A;  1NWL A;  2R0B A;  1KAK A;  1V3A A;  2H4G A;  2F6Z A;  4GRY A;  1PTV A;  1UAG A;  5I6V A;  3ZV2 A;  1NO6 A;  1KAV A;  1Q1M A;  4NWF A;  3BLU A;  3QCJ A;  3U96 A;  2WGP A;  4QBE A;  5KA2 A;  2X5O A;  2M3V A;  3QCG A;  5K24 A;  4DGX A;  2B4O A;  2ZMM A;  4GFV A;  2I75 A;  3S3H A;  4TVV A;  3QCD A;  2CFV A;  1GQQ A;  2HB1 A;  2F6F A;  1C87 A;  1L8G A;  3QCL A;  1JBW A;  4RH5 A;  2C46 A;  1W78 A;  2AM2 A;  2H03 A;  2CM2 A;  2WJP A;  2HCM A;  1RPM A;  1YWF A;  1ZZW A;  2Y66 A;  4KI9 A;  5EHP A;  1ZCL A;  3RZ2 A;  3A5J A;  3ZL8 A;  3D9C A;  1VHR A;  2FJN A;  2Y67 A;  1RXD A;  5J8R A;  1P3D A;  2QBP A;  5BUG A;  3V0E A;  2C7S A;  5KAC A;  2I4E A;  2B4U A;  1U24 A;  5KAA A;  5KA9 A;  4WU3 A;  3EZZ A;  5KA4 A;  2NTA A;  2GC6 A;  3PS5 A;  1X24 A;  4OHD A;  5BX1 A;  1WAX A;  1ECV A;  1OEV A;  5HDE A;  1WCH A;  2Y1O A;  2GC5 A;  3RGQ A;  3S3E A;  4OHE A;  2QCJ A;  2CMB A;  2DXP A;  2CM7 A;  3QKQ A;  1I57 A;  4NYH A;  1Q6T A;  3QCK A;  4BUB A;  4HJP A;  4JBC A;  2CNG A;  1C84 A;  1J4X A;  3EU0 A;  1XXV A;  2H02 A;  1J6U A;  1FGS A;  3S4E A;  2QDM A;  2F6W A;  3V0G A;  3V0F A;  1PTU A;  2Y96 A;  4B04 A;  4HV4 A;  2GJT A;  4PYH A;  3F9A A;  3GXH A;  2G59 A;  2OZ5 A;  2I4G A;  4YR8 B;  1NZ7 A;  2I5X A;  3QCF A;  2QBQ A;  2GWO A;  2UUO A;  1G7G A;  3LJ8 A;  4ZI4 A;  3QCC A;  2BV5 A;  5KAD A;  3V0H A;  2MBC A;  3EAX A;  4WTY A;  2A3K A;  4GWF A;  4I8N A;  1XBO A;  2HC2 A;  1EEN A;  1LAR A;  4RI4 A;  2CM3 A;  3I80 A;  2QCT A;  1G4W R;  3LK7 A;  3AWG A;  3PYZ A;  2CMA A;  2UUP A;  3O3L A;  1P15 A;  5IBS A;  3NME A;  2Y2F A;  3F99 A;  4DGP A;  5KA7 A;  1A5Y A;  2QEP A;  1FPR A;  3F81 A;  1Q6S A;  4QUM A;  4KYQ A;  2CNF A;  3EB1 A;  4NX8 A;  2HC1 A;  4MBB A;  2F6V A;  5BZZ A;  2XPC A;  4S0G A;  4PVG A;  4BUC A;  5KAB A;  3BLT A;  3D42 A;  1YN9 A;  2H04 A;  5A5E A;  3SR9 A;  1JLN A;  4R30 A;  1E8C A;  1QXK A;  4H1O A;  2BIJ A;  1OET A;  5AWX A;  1U25 A;  1YTN A;  2HVL A;  4R0T A;  2OOQ A;  1BZH A;  1GQY A;  2PI7 A;  2CNI A;  2ESB A;  4AZ1 A;  4RI5 A;  1EEO A;  2I6P A;  1YGR A;  2FJM A;  1NL9 A;  2I6O A;  2AHS A;  4CVM A;  5K23 A;  2VEV A;  1ONY A;  4QAP A;  4NWG A;  1SUG A;  4RDD A;  3ZM0 A;  3I36 A;  1NNY A;  1W7K A;  1G1H A;  2YDU A;  4CVL A;  3ZM5 A;  1BZJ A;  1G1F A;  2H4K A;  1GG4 A;  1PTY A;  4RKK A;  1NWE A;  1ZCK A;  4D3R A;  2CNE A;  4Z6B A;  1PA1 A;  4OHH A;  2JFG A;  4GRZ A;  3ZM1 A;  2PBN A;  4BPC A;  5K25 A;  5KA1 A;  1PXH A;  1PTT A;  4GE2 A;  5K22 A;  4NND A;  1M3G A;  3D1Q A;  3ZM6 A;  1I9T A;  1LYV A;  3CM3 A;  2F71 A;  1OEO X;  4H34 A;  2I3R A;  3S3K A;  3AWE A;  4OHI A;  4D3P A;  1O5Z A;  3NRS A;  2NT2 A;  5EHR A;  1BZC A;  2JJD A;  2PA5 A;  1P31 A;  4OHL A;  1PA9 A;  1XRI A;  2I6I A;  2PSZ A;  2VEW A;  3CWE A;  3QCZ A;  2PQ5 A;  3S4O A;  1EEH A;  2I4H A;  4C12 A;  4Y2E A;  1MKP A;  1ONZ A;  2P4D A;  3QKP A;  5KA3 A;  4HJQ A;  2Y68 A;  4ZIY A;  2QBS A;  5M43 A;  2VEU A;  1OHD A;  4QDI A;  4RH9 A;  1YPT A;  1C88 A;  2HY3 A;  4D3Q A;  3QCB A;  2JFH A;  3EMU A;  1I9S A;  2H4V A;  2GP0 A;  1JBV A;  2QBR A;  5GTJ A;  4HRF A;  2VEY A;  3F41 A;  3MVN A;  1GFY A;  1QZ0 A;  1JF7 A;  2NV5 A;  3O4T A;  3S3F A;  2A8B A;  3BM8 A;  2F46 A;  3HN7 A;  2F6T A;  2JFF A;  1G1G A;  2B4P A;  2I1Y A;  1Q6M A;  3MOZ A;  3MOW A;  3MMJ A;  2B4S A;  3RO1 A;  3D1H A;  2OUD A;  3ZMQ A;  2AZR A;  2GCB A;  3OLR A;  3SME A;  4GE5 A;  2VTD A;  3I7Z A;  1C83 A;  2B49 A;  2I6M A;  2G6Z A;  1OES A;  1Q6P A;  1WRM A;  3N0A A;  3OMH A;  3ZM3 A;  3F9B A;  1XXP A;  3H2X A;  1YZ4 A;  1FQ1 A;  2WTZ A;  3AWF A;  2HXP A;  4QBW A;  1ZC0 A;  1Q6J A;  2I42 A;  2Q47 A;  2VOS A;  3ZM2 A;  3B7O A;  1U26 A;  1YTW A;  1YTS A;  2P6X A;  2SHP A;  3QCE A;  2CMC A;  2HNQ A;  4Y14 A;  2BGE A;  1OHE A;  3GXG A;  4RHG A;  1PH0 A;  5KA0 A;  2BZL A;  1AAX A;  2CNH A;  2J16 A;  3ZMP A;  1C86 A;  4YAA A;  1C85 A;  1R6H A;  2B07 A;  1Q6N A;  4QUN A;  2VEX A;  2E0T A;  2OC3 A;  1FPZ A;  2F6Y A;  2ZN7 A;  4UAG A;  2Q05 A;  3O4U A;  1GWZ A;  1T4J A;  2NT7 A;  1PYN A;  1YFO A;  5KA8 A;  4JMJ A;  5BZX A;  1OEM X;  3A5K A;  3QCH A;  2VTE A; 
#chains in the Genus database with same CATH homology
 3QCN A;  2CJZ A;  3V0D A;  4GE6 A;  2PT0 A;  3O4S A;  1D5R A;  4WOH A;  3V0I A;  5IBM A;  1T49 A;  1XM2 A;  2QDC A;  1G7F A;  2QDP A;  3D44 A;  5K9W A;  4KYR A;  1T48 A;  4R0S A;  4ERC A;  3M4U A;  1LQF A;  4IKC A;  2NLK A;  2B3O A;  5LXQ B;  3QCM A;  4ZRT A;  1OEU A;  2RF6 A;  1L8K A;  5MMZ B;  3QCI A;  2J17 A;  3RGO A;  4ICZ A;  4JNB A;  4QAH A;  2CM8 A;  2F70 A;  3D1O A;  1G4U S;  2FH7 A;  2HNP A;  4GS0 A;  4GFU A;  2BGD A;  4J51 A;  2J16 B;  3BRH A;  4JMK A;  1OHC A;  3O5X A;  4ZN5 A;  1YGU A;  2NZ6 A;  2I3U A;  5K9V A;  3V0J A;  2IMG A;  4BJO A;  4WU2 A;  2I6J A;  1NWL A;  2R0B A;  1KAK A;  1V3A A;  2H4G A;  2F6Z A;  4GRY A;  1PTV A;  5I6V A;  3ZV2 A;  1NO6 A;  1KAV A;  1Q1M A;  4NWF A;  3BLU A;  3QCJ A;  3U96 A;  2WGP A;  4QBE A;  5KA2 A;  2M3V A;  3QCG A;  5K24 A;  4DGX A;  2B4O A;  2ZMM A;  4GFV A;  2I75 A;  3S3H A;  4TVV A;  3QCD A;  2CFV A;  2HB1 A;  2F6F A;  1C87 A;  1L8G A;  3QCL A;  4RH5 A;  2C46 A;  2H03 A;  2CM2 A;  2HCM A;  1RPM A;  1YWF A;  1ZZW A;  4KI9 A;  5EHP A;  1ZCL A;  3RZ2 A;  3A5J A;  3D9C A;  1VHR A;  2FJN A;  1RXD A;  5J8R A;  2QBP A;  5BUG A;  3V0E A;  2C7S A;  5KAC A;  2I4E A;  2B4U A;  1U24 A;  5KAA A;  5KA9 A;  4WU3 A;  3EZZ A;  5KA4 A;  2NTA A;  3PS5 A;  1X24 A;  4OHD A;  5BX1 A;  1WAX A;  1ECV A;  1OEV A;  5HDE A;  1WCH A;  3RGQ A;  3S3E A;  4OHE A;  2QCJ A;  2CMB A;  2DXP A;  2CM7 A;  3QKQ A;  1I57 A;  4NYH A;  1Q6T A;  3QCK A;  4HJP A;  4JBC A;  2CNG A;  1C84 A;  1J4X A;  3EU0 A;  1XXV A;  2H02 A;  3S4E A;  2QDM A;  2F6W A;  3V0G A;  3V0F A;  1PTU A;  2Y96 A;  4B04 A;  2GJT A;  4PYH A;  3F9A A;  3GXH A;  2G59 A;  2OZ5 A;  2I4G A;  4YR8 B;  1NZ7 A;  2I5X A;  3QCF A;  2QBQ A;  2GWO A;  1G7G A;  3LJ8 A;  4ZI4 A;  3QCC A;  2BV5 A;  5KAD A;  3V0H A;  2MBC A;  3EAX A;  4WTY A;  2A3K A;  4GWF A;  4I8N A;  1XBO A;  2HC2 A;  1EEN A;  1LAR A;  4RI4 A;  2CM3 A;  3I80 A;  2QCT A;  1G4W R;  3AWG A;  2CMA A;  3O3L A;  1P15 A;  5IBS A;  3NME A;  2Y2F A;  3F99 A;  4DGP A;  5KA7 A;  1A5Y A;  2QEP A;  1FPR A;  3F81 A;  1Q6S A;  4QUM A;  4KYQ A;  2CNF A;  3EB1 A;  4NX8 A;  2HC1 A;  4MBB A;  2F6V A;  5BZZ A;  4S0G A;  4PVG A;  5KAB A;  3BLT A;  3D42 A;  1YN9 A;  2H04 A;  3SR9 A;  1JLN A;  4R30 A;  1QXK A;  4H1O A;  2BIJ A;  1OET A;  5AWX A;  1U25 A;  1YTN A;  2HVL A;  4R0T A;  2OOQ A;  1BZH A;  2PI7 A;  2CNI A;  2ESB A;  4AZ1 A;  4RI5 A;  1EEO A;  2I6P A;  1YGR A;  2FJM A;  1NL9 A;  2I6O A;  2AHS A;  5K23 A;  2VEV A;  1ONY A;  4QAP A;  4NWG A;  1SUG A;  4RDD A;  3ZM0 A;  3I36 A;  1NNY A;  2YDU A;  1G1H A;  1BZJ A;  1G1F A;  2H4K A;  1PTY A;  4RKK A;  1NWE A;  1ZCK A;  4D3R A;  2CNE A;  4Z6B A;  1PA1 A;  4OHH A;  4GRZ A;  3ZM1 A;  2PBN A;  4BPC A;  5K25 A;  5KA1 A;  1PXH A;  1PTT A;  4GE2 A;  5K22 A;  4NND A;  1M3G A;  3D1Q A;  1I9T A;  1LYV A;  3CM3 A;  2F71 A;  1OEO X;  4H34 A;  2I3R A;  3S3K A;  3AWE A;  4OHI A;  4D3P A;  2NT2 A;  5EHR A;  1BZC A;  2JJD A;  2PA5 A;  4OHL A;  1PA9 A;  1XRI A;  2I6I A;  2PSZ A;  2VEW A;  3CWE A;  2PQ5 A;  3S4O A;  2I4H A;  4Y2E A;  1MKP A;  1ONZ A;  2P4D A;  3QKP A;  5KA3 A;  4HJQ A;  2QBS A;  5M43 A;  2VEU A;  1OHD A;  4RH9 A;  1YPT A;  1C88 A;  2HY3 A;  4D3Q A;  3QCB A;  3EMU A;  1I9S A;  2H4V A;  2GP0 A;  2QBR A;  5GTJ A;  4HRF A;  2VEY A;  3F41 A;  1GFY A;  1QZ0 A;  1JF7 A;  2NV5 A;  3O4T A;  3S3F A;  2A8B A;  3BM8 A;  2F46 A;  2F6T A;  1G1G A;  2B4P A;  2I1Y A;  1Q6M A;  3MOZ A;  3MOW A;  3MMJ A;  2B4S A;  3RO1 A;  3D1H A;  2OUD A;  3ZMQ A;  2AZR A;  3OLR A;  3SME A;  4GE5 A;  3I7Z A;  1C83 A;  2B49 A;  2I6M A;  2G6Z A;  1OES A;  1Q6P A;  1WRM A;  3N0A A;  3OMH A;  3ZM3 A;  3F9B A;  1XXP A;  3H2X A;  1YZ4 A;  1FQ1 A;  3AWF A;  2HXP A;  4QBW A;  1ZC0 A;  1Q6J A;  2I42 A;  2Q47 A;  3ZM2 A;  3B7O A;  1U26 A;  1YTW A;  1YTS A;  2P6X A;  2SHP A;  3QCE A;  2CMC A;  2HNQ A;  4Y14 A;  2BGE A;  1OHE A;  3GXG A;  4RHG A;  1PH0 A;  5KA0 A;  2BZL A;  1AAX A;  2CNH A;  2J16 A;  3ZMP A;  1C86 A;  4YAA A;  1C85 A;  1R6H A;  2B07 A;  1Q6N A;  4QUN A;  2VEX A;  2E0T A;  2OC3 A;  1FPZ A;  2F6Y A;  2ZN7 A;  2Q05 A;  3O4U A;  1GWZ A;  1T4J A;  2NT7 A;  1PYN A;  1YFO A;  5KA8 A;  4JMJ A;  5BZX A;  1OEM X;  3A5K A;  3QCH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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