5VK0B

Crystal structure of human mdm2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor pmi
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
12
structure length
11
Chain Sequence
TSFAEYWLLSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase/ligase inhibitor
molecule keywords E3 ubiquitin-protein ligase Mdm2
publication title Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
pubmed doi rcsb
total genus 2
structure length 11
sequence length 12
chains with identical sequence D, F, H, J, L, N, P, R, T, V, X
ec nomenclature
pdb deposition date 2017-04-20
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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