5VOFL

Desgla-xas195a bound to aptamer 11f7t and rivaroxaban
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
51
structure length
51
Chain Sequence
LCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor/rna
molecule keywords Coagulation factor X
publication title Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.
pubmed doi rcsb
source organism Homo sapiens
total genus 11
structure length 51
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2017-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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