5XJCI

Cryo-em structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Total Genus 181
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
664
structure length
566
Chain Sequence
LRSHPLPETAVFLKLSPESAEEYYLKSSDRLDEAAQRLATVNDERFVSKAGKSNYHELCDLISQNPDKQSLNVDAIIRGGLTRFTQLGKLWCSLADYYISGHFEKARDVYEEAITVMTVRDFTQVFDSYEESMIAAKMETASEEEEDDVDLELRLARFELISRRPLLLNSVLLRQNHHVHEWHKRVALGRPREIINTYTEAVQPFKATGKPHTLWKFYEDNGQLDDARVIATKVNFKQVDDLASVWCCGELELRHENYDEALRLLRKATLPARRAEYFDGSEPVQNRVYKSLKWSMLADLEESLGTFQSYDRILDLRIATPQIVINYAFLEEHKYFEESFKAYESLFKWPNVSDIWSTYLGGRKLERARDLFLDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIAEIYGVTHTRGIYQHAREMCLRFADMECGEIDRARAIYSTWKDFEVRHGNEDTIKEMLRIRRSVQATYFMASQMLKVSGSATGTVAPGQSGMDDMKLLEQRLAAEAERDQPLRAQSKLFVRSDASREELAELAQQVNPEEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title An Atomic Structure of the Human Spliceosome
pubmed doi rcsb
molecule tags Splicing
molecule keywords Pre-mRNA-processing-splicing factor 8
total genus 181
structure length 566
sequence length 664
ec nomenclature
pdb deposition date 2017-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF13181 TPR_8 Tetratricopeptide repeat
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...