5XJCb

Cryo-em structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
86
structure length
86
Chain Sequence
GKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Splicing
molecule keywords Pre-mRNA-processing-splicing factor 8
publication title An Atomic Structure of the Human Spliceosome
pubmed doi rcsb
total genus 12
structure length 86
sequence length 86
chains with identical sequence i
ec nomenclature
pdb deposition date 2017-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
b PF01423 LSM LSM domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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