6INSE

X-ray analysis of the single chain b29-a1 peptide-linked insulin molecule. a completely inactive analogue
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
50
structure length
50
Chain Sequence
FVNQHLCGSHLVEALYLVCGERGFFYTPKGIVEQCCTSICSLYQLENYCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hormone
molecule keywords INSULIN
publication title X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
pubmed doi rcsb
source organism Sus scrofa
total genus 3
structure length 50
sequence length 50
chains with identical sequence F
ec nomenclature
pdb deposition date 1992-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 6insE00
5L3NA 1GZRB 4XSSB 1GZZB 5L3MA 2GF1A 5L3LA 1EFEA 2L29B 1IGLA 3GF1A 1IMXA 1H02B 1PMXA 1B9GA 2KQPA 2DSRI 1TGRA 1ZEIA 1H59A 1WQJI 2JZQA 6INSE 2LWZA 3KR3D 1BQTA 2KJIA 1GZYB 2DSPI 1SJUA 3LRIA 2DSQC
chains in the Genus database with same CATH superfamily
5L3NA 1GZRB 4XSSB 1GZZB 5L3MA 3F2DA 2GF1A 5L3LA 3F2CA 1EFEA 2L14B 2L29B 1IGLA 3GF1A 1IMXA 1H02B 1PMXA 3F2BA 1B9GA 2KQPA 2DSRI 1TGRA 1ZEIA 1H59A 1WQJI 2JZQA 6INSE 2LWZA 3KR3D 1BQTA 2KJIA 1GZYB 2DSPI 1SJUA 3LRIA 2DSQC
chains in the Genus database with same CATH topology
5L3NA 1GZRB 4XSSB 1GZZB 5L3MA 2GF1A 5L3LA 1EFEA 2L29B 1IGLA 3GF1A 1IMXA 1H02B 1PMXA 1B9GA 2KQPA 2DSRI 1TGRA 1ZEIA 1H59A 1WQJI 2JZQA 6INSE 2LWZA 3KR3D 1BQTA 2KJIA 1GZYB 2DSPI 1SJUA 3LRIA 2DSQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L3N A;  1GZR B;  4XSS B;  1GZZ B;  5L3M A;  2GF1 A;  5L3L A;  1EFE A;  2L29 B;  1IGL A;  3GF1 A;  1IMX A;  1H02 B;  1PMX A;  1B9G A;  2KQP A;  2DSR I;  1TGR A;  1ZEI A;  1H59 A;  1WQJ I;  2JZQ A;  6INS E;  2LWZ A;  3KR3 D;  1BQT A;  2KJI A;  1GZY B;  2DSP I;  1SJU A;  3LRI A;  2DSQ C; 
#chains in the Genus database with same CATH topology
 5L3N A;  1GZR B;  4XSS B;  1GZZ B;  5L3M A;  3F2D A;  2GF1 A;  5L3L A;  3F2C A;  1EFE A;  2L14 B;  2L29 B;  1IGL A;  3GF1 A;  1IMX A;  1H02 B;  1PMX A;  3F2B A;  1B9G A;  2KQP A;  2DSR I;  1TGR A;  1ZEI A;  1H59 A;  1WQJ I;  2JZQ A;  6INS E;  2LWZ A;  3KR3 D;  1BQT A;  2KJI A;  1GZY B;  2DSP I;  1SJU A;  3LRI A;  2DSQ C; 
#chains in the Genus database with same CATH homology
 5L3N A;  1GZR B;  4XSS B;  1GZZ B;  5L3M A;  2GF1 A;  5L3L A;  1EFE A;  2L29 B;  1IGL A;  3GF1 A;  1IMX A;  1H02 B;  1PMX A;  1B9G A;  2KQP A;  2DSR I;  1TGR A;  1ZEI A;  1H59 A;  1WQJ I;  2JZQ A;  6INS E;  2LWZ A;  3KR3 D;  1BQT A;  2KJI A;  1GZY B;  2DSP I;  1SJU A;  3LRI A;  2DSQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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