6DCWH

Crystal structure of human anti-tau antibody cbtau-27.1 fab in complex with a human tau peptide
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
223
structure length
223
Chain Sequence
QVQLVESGPEMRKPGESLKISCKTSGYIFSDYWTAWVRQLPGKGLQWMGIIYSGDSDTRYHPSVQGHVTMSTDSSLTTAYLQWSSLKASDTGIYYCARLDARVDAGWQLDSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Light chain of CBTAU27.1 Fab
total genus 37
structure length 223
sequence length 223
ec nomenclature
pdb deposition date 2018-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF07654 C1-set Immunoglobulin C1-set domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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