6KN9D

Crystal structure of human interleukin 18 receptor beta extracellular domain in complex with an antagonistic scfv
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
252
structure length
220
Chain Sequence
GPLDPEVQLVESGGGLVQPGGSLRLSCAASGFNLYYSSMHWVRQAPGKGLEWVASIYSSYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSSFSHGYGWYGLDYWGQGTLVTVPSSLSASVGDRVTITCRASSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYGYAGLITFGQGTKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytokine
molecule keywords Interleukin-18 receptor accessory protein
publication title A Synthetic Human Antibody Antagonizes IL-18R beta Signaling Through an Allosteric Mechanism.
pubmed doi rcsb
source organism Homo sapiens
total genus 43
structure length 220
sequence length 252
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2019-08-05
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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