6LTDA

Crystal structure of nonribosomal peptide synthetases (nrps), fmoa3 (s1046a)-alpha-methyl-l-serine-amp bound form
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
966
structure length
883
Chain Sequence
AAELPPLVPEPGDAGQPFPLTPTQQALWVGRAYGYFEWERPELDLARYRRAWERLVAHHPGLRTVVRPDGTQHVLERPGPVPITVEDLRQDPDAVRRLEESRLDPGTWPMFDLRVVLLSGRVRVQLGIDLQLMDASSLFLNLFSDLVTLYDDPDAALASQKLAFRDFARWLEEDVRGGARWRADWAYWQERLDGLPPAPDLPAARKFERCMVRCPAEEFALLRERALAHGLTETELLVGAFAEVLRGWSSDPAFTLNVPVFQRFDVPGIEDVIGDYTNPILLEARPEGRTVAERIVALAARLRADTRHASVNGVEVLRELARRRGLAAAAMPVVVTSLLGLPSAARSITEFGTEVHSITQTPQVSLDFQIRPEDGELRLVWDHRSGAFAPGVVEGAFEAFLDLVGRMLADEPGHGVWEAPFADMRSRRDRAVWNETNDTAEPVPAVLLQERFFAQARRTPDAEAVVASGLRLTYDELARHAYRIGNTLRERGVRPGDLVGVVMEKGWEQYAAVYGILAAGGAYLPIDAASPRGRVARLLESAGAGIVLTQSRLRDELDLPAGTTVLRADTDFETASTAPLTPVQGPDDPAYVIYTGEPKGVVVAHRGVANLVRDVRRRFAVTPADRLLALSGLHFDASVYDVFGPLACGATVVVPPPFRRAEPDVWAELVRDERVTFWNSVPVLLELLVGEAESRDDRPLATLRLAVVSGDWIPLDLPGRARAQAPGLRVVGSGGPTETICWSLFHPIDAVDPQWTSIPYGKPIANQRYYIVDRDLRPRPTWARGEMAVASPLGLALGYLNDPERTAAKFVTLPGTGERAYLTGDFGRLLPDGGIEILGREDFQGQRIELGEIGVRAAADVVRRLLPELPLTANGKVDRLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Biosynthetic protein
molecule keywords Nonribosomal peptide synthetase
publication title Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-alpha-methyl-L-serine-AMP bound form
rcsb
source organism Streptomyces sp. sp080513ge-23
total genus 193
structure length 883
sequence length 966
chains with identical sequence B
ec nomenclature
pdb deposition date 2020-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00501 AMP-binding AMP-binding enzyme
A PF00550 PP-binding Phosphopantetheine attachment site
A PF00668 Condensation Condensation domain
A PF13193 AMP-binding_C AMP-binding enzyme C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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